#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
368	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
369	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
857	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Plaisance V (2006)	16831872	145324	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
858	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
859	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
860	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Torii S (2004)	15028737	172189	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
861	125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	unknown	target	Gomi H (2005)	16216924	172188	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
3436	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Horia E (2007)	17052999	173829	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3437	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Ramakers JD (2007)	17610002	173828	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3438	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Selvaraj RK (2006)	16702329	173830	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3439	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Chambrier C (2002)	12055328	173831	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3440	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Iwata Y (2001)	11552681	173832	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3718	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3719	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3747	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3748	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
4143	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4144	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Demetri GD (1999)	10097144	174284	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4145	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Petrova TV (1999)	10200320	174285	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4146	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Kitamura S (1999)	10076568	174286	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4147	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Baek SJ (2003)	12475986	174281	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4148	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Camp HS (1999)	10214942	174282	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4149	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Satoh T (1999)	10222233	174283	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4451	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Matchett GA (2009)	19298752	174518	221	Enflurane	Efrane|Enflurane|Alyrane|Ethrane|Enflurano|2-chloro-1,1,2-trifluoroethyl difluoromethyl ether|Enfluranum|Methylflurether	enflurane|ethrane liq inh|ethr	DRUGBANK	DB00228	C3H2ClF5O	small molecule	N01AB04	13838-16-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPGQOUSTVILISH-UHFFFAOYSA-N
4693	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Desreumaux P (2006)	16939423	174608	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4694	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Schwab M (2008)	18544567	174605	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4695	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Linard C (2008)	18077625	174606	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4696	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Rousseaux C (2005)	15824083	174607	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
5080	109954	3752	RP4-773A18.7	KCND3	KCND3L|KCND3S|KSHIVB|KV4.3|SCA19|SCA22	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	273	Disopyramide	Disopyramidum|Disopiramida	rythmodan cap 150mg|norpace ca	DRUGBANK	DB00280	C21H29N3O	small molecule	C01BA03	3737-09-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVTNFZQICZKOEM-UHFFFAOYNA-N
5081	109953	3751	-	KCND2	KV4.2|RK5	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	273	Disopyramide	Disopyramidum|Disopiramida	rythmodan cap 150mg|norpace ca	DRUGBANK	DB00280	C21H29N3O	small molecule	C01BA03	3737-09-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVTNFZQICZKOEM-UHFFFAOYNA-N
5543	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inhibitor	target	Punke MA (2007)	17456683	175184	314	Amitriptyline	3-(10,11-dihydro-5H-Dibenzo[a,D]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene|Amitriptylinum|Amitriptilina|3-(10,11-dihydro-5H-Dibenzo(a,D)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine|10,11-dihydro-5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,D)cycloheptene|Amitriptyline|10,11-dihydro-N,N-Dimethyl-5H-dibenzo(a,D)heptalene-delta(5),gamma-propylamine|5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,D][1,4]cycloheptadiene|Amitriptylin|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptatriene	amitriptyline hydrochloride|ip	DRUGBANK	DB00321	C20H23N	small molecule	N06AA09|N06CA01	50-48-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRMDCWKBEZIMAB-UHFFFAOYSA-N
5546	109954	3752	RP4-773A18.7	KCND3	KCND3L|KCND3S|KSHIVB|KV4.3|SCA19|SCA22	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	314	Amitriptyline	3-(10,11-dihydro-5H-Dibenzo[a,D]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene|Amitriptylinum|Amitriptilina|3-(10,11-dihydro-5H-Dibenzo(a,D)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine|10,11-dihydro-5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,D)cycloheptene|Amitriptyline|10,11-dihydro-N,N-Dimethyl-5H-dibenzo(a,D)heptalene-delta(5),gamma-propylamine|5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,D][1,4]cycloheptadiene|Amitriptylin|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptatriene	amitriptyline hydrochloride|ip	DRUGBANK	DB00321	C20H23N	small molecule	N06AA09|N06CA01	50-48-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRMDCWKBEZIMAB-UHFFFAOYSA-N
5547	109953	3751	-	KCND2	KV4.2|RK5	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	314	Amitriptyline	3-(10,11-dihydro-5H-Dibenzo[a,D]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene|Amitriptylinum|Amitriptilina|3-(10,11-dihydro-5H-Dibenzo(a,D)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine|10,11-dihydro-5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,D)cycloheptene|Amitriptyline|10,11-dihydro-N,N-Dimethyl-5H-dibenzo(a,D)heptalene-delta(5),gamma-propylamine|5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,D][1,4]cycloheptadiene|Amitriptylin|5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptatriene	amitriptyline hydrochloride|ip	DRUGBANK	DB00321	C20H23N	small molecule	N06AA09|N06CA01	50-48-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRMDCWKBEZIMAB-UHFFFAOYSA-N
5606	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	activator	target	Cho MC (2003)	12689521	175243	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5607	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	activator	target	Lehmann JM (1997)	9013583	175242	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
6629	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Johnson BA (2000)	10764590	175913	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
6630	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Camp HS (2000)	10871190	175912	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
6631	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Rieusset J (1999)	10548525	175911	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
6632	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Kameda N (2000)	10707565	175910	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
6633	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
6634	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Su JL (1999)	10475242	175909	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
7118	109954	3752	RP4-773A18.7	KCND3	KCND3L|KCND3S|KSHIVB|KV4.3|SCA19|SCA22	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	450	Imipramine	N-(-dimethylaminopropyl)iminodibenzyl|Imipraminum|Antideprin|3-(5H-DIBENZO[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine|10,11-dihydro-N,N-Dimethyl-5H-dibenz[b,F]azepine-5-propanamine|Irmin|Imipramine|Imizine|5-[3-(dimethylamino)Propyl]-10,11-dihydro-5H-dibenz[b,F]azepine|Melipramine|N-(gamma-Dimethylaminopropyl)iminodibenzyl|Imipramin	tofranil|imipramine tab 25mg|i	DRUGBANK	DB00458	C19H24N2	small molecule	N06AA02	50-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCGWQEUPMDMJNV-UHFFFAOYSA-N
7119	109953	3751	-	KCND2	KV4.2|RK5	9606	Homo sapiens	inhibitor	target	Casis O (1998)	9781919	174867	450	Imipramine	N-(-dimethylaminopropyl)iminodibenzyl|Imipraminum|Antideprin|3-(5H-DIBENZO[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine|10,11-dihydro-N,N-Dimethyl-5H-dibenz[b,F]azepine-5-propanamine|Irmin|Imipramine|Imizine|5-[3-(dimethylamino)Propyl]-10,11-dihydro-5H-dibenz[b,F]azepine|Melipramine|N-(gamma-Dimethylaminopropyl)iminodibenzyl|Imipramin	tofranil|imipramine tab 25mg|i	DRUGBANK	DB00458	C19H24N2	small molecule	N06AA02	50-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCGWQEUPMDMJNV-UHFFFAOYSA-N
7366	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Zhu YX (2013)	22966948	176371	472	Lenalidomide	1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline|IMid-1|CC-5013|IMiD3|Revlimid|3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione|CDC 501	revlimid	DRUGBANK	DB00480	C13H13N3O3	small molecule	L04AX04	191732-72-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GOTYRUGSSMKFNF-UHFFFAOYSA-N
9928	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Scarsi M (2007)	17082235	178076	721	Nateglinide	-	starlix|starlix 180mg|nateglin	DRUGBANK	DB00731	C19H27NO3	small molecule	A10BX03	105816-04-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OELFLUMRDSZNSF-YJEKIOLLSA-N
10117	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Imming P (2006)	17016423	171742	743	Isoflurane	1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether|Forene|Aerrane|Forane|Ethane|Isofluranum|Isoflurano|Isoflurane	isoflurane usp|terrell|isoflur	DRUGBANK	DB00753	C3H2ClF5O	small molecule	N01AB06	26675-46-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PIWKPBJCKXDKJR-UHFFFAOYSA-N
10118	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Overington JP (2006)	17139284	171741	743	Isoflurane	1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether|Forene|Aerrane|Forane|Ethane|Isofluranum|Isoflurano|Isoflurane	isoflurane usp|terrell|isoflur	DRUGBANK	DB00753	C3H2ClF5O	small molecule	N01AB06	26675-46-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PIWKPBJCKXDKJR-UHFFFAOYSA-N
10119	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Matchett GA (2009)	19298752	174518	743	Isoflurane	1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether|Forene|Aerrane|Forane|Ethane|Isofluranum|Isoflurano|Isoflurane	isoflurane usp|terrell|isoflur	DRUGBANK	DB00753	C3H2ClF5O	small molecule	N01AB06	26675-46-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PIWKPBJCKXDKJR-UHFFFAOYSA-N
10549	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Desreumaux P (2006)	16939423	174608	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10550	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Schwab M (2008)	18544567	174605	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10551	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Linard C (2008)	18077625	174606	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10552	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Rousseaux C (2005)	15824083	174607	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
11859	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Scarsi M (2007)	17082235	178076	902	Repaglinide	Repaglinidum|Surepost|AG-EE 388 ZW|Prandin|Repaglinida|AG-EE 623 ZW	apo-repaglinide|repaglinide an	DRUGBANK	DB00912	C27H36N2O4	small molecule	A10BD14|A10BX02	135062-02-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAEKWTJYAYMJKF-QHCPKHFHSA-N
12352	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Yamagishi S (2004)	15617852	179382	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12353	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Yamagishi S (2007)	17691961	179383	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12354	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Kurtz TW (2008)	18580862	179381	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12355	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Kurtz TW (2005)	15868121	179386	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12356	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Imayama I (2006)	16938288	179384	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12357	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Yamagishi S (2005)	16154710	179385	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12358	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	partial agonist	target	Tagami T (2009)	19147680	171006	956	Telmisartan	4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid|4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid|Telmisartan|4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid|Micardis|BIBR 277|4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid	telmisartan/hctz|telmisartan|t	DRUGBANK	DB00966	C33H30N4O2	small molecule	C09DA07|C09CA07|C09DB04	144701-48-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMMXLENWKUUMAY-UHFFFAOYSA-N
12739	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Desreumaux P (2006)	16939423	174608	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12740	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Iacucci M (2010)	20151072	179657	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12741	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Tursi A (2009)	19708827	179658	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12742	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Linard C (2008)	18077625	174606	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12937	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Imming P (2006)	17016423	171742	1017	Methoxyflurane	Penthrane|Methoflurane|Methoxyfluranum|Methoxyfluran|Methyl 1,1-difluoro-2,2-dichloroethyl ether|Methoxyfluoran|Metoxiflurano	-	DRUGBANK	DB01028	C3H4Cl2F2O	small molecule	N02BG09	76-38-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFKMCNOHBTXSMU-UHFFFAOYSA-N
12938	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Overington JP (2006)	17139284	171741	1017	Methoxyflurane	Penthrane|Methoflurane|Methoxyfluranum|Methoxyfluran|Methyl 1,1-difluoro-2,2-dichloroethyl ether|Methoxyfluoran|Metoxiflurano	-	DRUGBANK	DB01028	C3H4Cl2F2O	small molecule	N02BG09	76-38-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFKMCNOHBTXSMU-UHFFFAOYSA-N
12939	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Elliott JR (1992)	1336744	179767	1017	Methoxyflurane	Penthrane|Methoflurane|Methoxyfluranum|Methoxyfluran|Methyl 1,1-difluoro-2,2-dichloroethyl ether|Methoxyfluoran|Metoxiflurano	-	DRUGBANK	DB01028	C3H4Cl2F2O	small molecule	N02BG09	76-38-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFKMCNOHBTXSMU-UHFFFAOYSA-N
13097	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Zhu YX (2013)	22966948	176371	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13284	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	activator	target	Dill J (2010)	20089905	179904	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13403	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Scarsi M (2007)	17082235	178076	1055	Glipizide	Glican|Glucotrol|Gluco-rite|Glibetin|Glipizida|Minidiab|Mindiab|Glipizidum|Glydiazinamide|Aldiab|Glucolip|Melizide|Dipazide|CP-28,720|Glibenese|Glidiab|Glipid|Glupitel|Minodiab|CP 28,720|CP 28720|Sucrazide|Glyde|1-Cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea|Napizide|Glucozide|Glupizide|Minidab|Digrin|Ozidia|N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-n'-cyclohexylurea|K 4024	glucotrol|glipizide|glipizidee	DRUGBANK	DB01067	C21H27N5O4S	small molecule	A10BB07	29094-61-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZJJXGWJIGJFDTL-UHFFFAOYSA-N
13914	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inhibitor	target	Bett GC (2008)	18096604	180229	1103	Nifedipine	Adalat|Nifedipine|4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester|Nifedipres|Nifecard|Nifedipino|Coracten|Nifecor|Procardia|Nifedipinum|Adapine	nifedipine|adalat xl plus|adal	DRUGBANK	DB01115	C17H18N2O6	small molecule	C08CA55|C08CA05|C08GA01	21829-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYIMSNHJOBLJNT-UHFFFAOYSA-N
14035	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Miyazaki Y (2004)	15356026	180300	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14036	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14037	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Lehmann JM (1995)	7768881	180298	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14038	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Willson TM (1996)	8576907	180299	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14039	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Sugii S (2009)	20018750	180296	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14040	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Spiegelman BM (1998)	9568680	180297	1120	Pioglitazone	Pioglitazonum|Pioglitazona|(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione|Pioglitazone	phl-pioglitazone|pms-pioglitaz	DRUGBANK	DB01132	C19H20N2O3S	small molecule	A10BD12|A10BG03|A10BD09|A10BD05|A10BD06	111025-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYAFETHFCAUJAY-UHFFFAOYSA-N
14624	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Imming P (2006)	17016423	171742	1177	Desflurane	(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether|Desflurano|Desflurane|Suprane|1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane|Desfluranum|Difluoromethyl 1,2,2,2-tetrafluoroethyl ether	desflurane|suprane	DRUGBANK	DB01189	C3H2F6O	small molecule	N01AB07	57041-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPYMFVXJLLWWEU-UHFFFAOYSA-N
14625	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Overington JP (2006)	17139284	171741	1177	Desflurane	(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether|Desflurano|Desflurane|Suprane|1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane|Desfluranum|Difluoromethyl 1,2,2,2-tetrafluoroethyl ether	desflurane|suprane	DRUGBANK	DB01189	C3H2F6O	small molecule	N01AB07	57041-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPYMFVXJLLWWEU-UHFFFAOYSA-N
14626	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Matchett GA (2009)	19298752	174518	1177	Desflurane	(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether|Desflurano|Desflurane|Suprane|1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane|Desfluranum|Difluoromethyl 1,2,2,2-tetrafluoroethyl ether	desflurane|suprane	DRUGBANK	DB01189	C3H2F6O	small molecule	N01AB07	57041-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPYMFVXJLLWWEU-UHFFFAOYSA-N
15206	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Imming P (2006)	17016423	171742	1224	Sevoflurane	Sevoflurano|Sevoflurane|1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane|Sevofluran|Sevofluranum	ultane|sevorane af|sevoflurane	DRUGBANK	DB01236	C4H3F7O	small molecule	N01AB08	28523-86-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFEYYRMXOJXZRJ-UHFFFAOYSA-N
15207	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	inducer	target	Overington JP (2006)	17139284	171741	1224	Sevoflurane	Sevoflurano|Sevoflurane|1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane|Sevofluran|Sevofluranum	ultane|sevorane af|sevoflurane	DRUGBANK	DB01236	C4H3F7O	small molecule	N01AB08	28523-86-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFEYYRMXOJXZRJ-UHFFFAOYSA-N
15394	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Scarsi M (2007)	17082235	178076	1240	Mitiglinide	-	-	DRUGBANK	DB01252	C19H25NO3	small molecule	A10BX08	145375-43-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WPGGHFDDFPHPOB-BBWFWOEESA-N
16372	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Tenenbaum A (2005)	16168052	181267	1343	Bezafibrate	2-(P-(2-(P-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid|Befizal|Bezatol sr (tn)|Bezafibratum|Bezafibrato|Cedur|Bezafibrat|Bezalip	pms-bezafibrate|bezalip tab 20	DRUGBANK	DB01393	C19H20ClNO4	small molecule	C10AB02	41859-67-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IIBYAHWJQTYFKB-UHFFFAOYSA-N
16859	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Maneckjee R (1988)	2828423	181475	1442	Etorphine	Etorphinum	-	DRUGBANK	DB01497	C25H33NO4	small molecule	-	14521-96-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAHCBJPUTCKATP-HBDRVVKHSA-N
16860	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Audigier Y (1980)	6247160	181474	1442	Etorphine	Etorphinum	-	DRUGBANK	DB01497	C25H33NO4	small molecule	-	14521-96-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAHCBJPUTCKATP-HBDRVVKHSA-N
16861	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Pfeiffer A (1982)	6124875	181473	1442	Etorphine	Etorphinum	-	DRUGBANK	DB01497	C25H33NO4	small molecule	-	14521-96-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAHCBJPUTCKATP-HBDRVVKHSA-N
16862	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Stojilkovic SS (1987)	3036471	181472	1442	Etorphine	Etorphinum	-	DRUGBANK	DB01497	C25H33NO4	small molecule	-	14521-96-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAHCBJPUTCKATP-HBDRVVKHSA-N
16863	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Pesce G (1987)	3037028	181471	1442	Etorphine	Etorphinum	-	DRUGBANK	DB01497	C25H33NO4	small molecule	-	14521-96-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAHCBJPUTCKATP-HBDRVVKHSA-N
16918	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	unknown	target	Law PY (1985)	2982865	181499	1488	Diprenorphine	Diprenorfin	-	DRUGBANK	DB01548	C26H35NO4	small molecule	-	14357-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OIJXLIIMXHRJJH-KNLIIKEYSA-N
16919	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	unknown	target	Pfeiffer A (1982)	6287305	181498	1488	Diprenorphine	Diprenorfin	-	DRUGBANK	DB01548	C26H35NO4	small molecule	-	14357-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OIJXLIIMXHRJJH-KNLIIKEYSA-N
16920	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	unknown	target	Cvejic S (1996)	8626742	181500	1488	Diprenorphine	Diprenorfin	-	DRUGBANK	DB01548	C26H35NO4	small molecule	-	14357-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OIJXLIIMXHRJJH-KNLIIKEYSA-N
16921	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	unknown	target	Pfeiffer A (1982)	6124875	181473	1488	Diprenorphine	Diprenorfin	-	DRUGBANK	DB01548	C26H35NO4	small molecule	-	14357-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OIJXLIIMXHRJJH-KNLIIKEYSA-N
16922	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	unknown	target	Chang KJ (1981)	6270660	181497	1488	Diprenorphine	Diprenorfin	-	DRUGBANK	DB01548	C26H35NO4	small molecule	-	14357-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OIJXLIIMXHRJJH-KNLIIKEYSA-N
16983	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Koman A (1987)	2855368	181514	1505	Dihydromorphine	-	-	DRUGBANK	DB01565	C17H21NO3	small molecule	-	509-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJVCSMSMFSCRME-KBQPJGBKSA-N
16984	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Ho CL (1985)	2985086	181515	1505	Dihydromorphine	-	-	DRUGBANK	DB01565	C17H21NO3	small molecule	-	509-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJVCSMSMFSCRME-KBQPJGBKSA-N
16985	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Maneckjee R (1988)	2828423	181475	1505	Dihydromorphine	-	-	DRUGBANK	DB01565	C17H21NO3	small molecule	-	509-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJVCSMSMFSCRME-KBQPJGBKSA-N
16986	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Ishizuka Y (1987)	2835832	181512	1505	Dihydromorphine	-	-	DRUGBANK	DB01565	C17H21NO3	small molecule	-	509-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJVCSMSMFSCRME-KBQPJGBKSA-N
16987	115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	agonist	target	Liebmann C (1991)	1654566	181513	1505	Dihydromorphine	-	-	DRUGBANK	DB01565	C17H21NO3	small molecule	-	509-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJVCSMSMFSCRME-KBQPJGBKSA-N
17705	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1684	Naphthalen-1-Yl-Acetic Acid	-	-	DRUGBANK	DB01750	C12H10O2	small molecule	-	86-87-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PRPINYUDVPFIRX-UHFFFAOYSA-N
18891	109942	3739	-	KCNA4	HBK4|HK1|HPCN2|HUKII|KCNA4L|KCNA8|KV1.4|PCN2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2206	Arginineamide	-	-	DRUGBANK	DB02299	C6H16N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ULEBESPCVWBNIF-BYPYZUCNSA-O
18892	109942	3739	-	KCNA4	HBK4|HK1|HPCN2|HUKII|KCNA4L|KCNA8|KV1.4|PCN2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2206	Arginineamide	-	-	DRUGBANK	DB02299	C6H16N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ULEBESPCVWBNIF-BYPYZUCNSA-O
18893	109942	3739	-	KCNA4	HBK4|HK1|HPCN2|HUKII|KCNA4L|KCNA8|KV1.4|PCN2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2206	Arginineamide	-	-	DRUGBANK	DB02299	C6H16N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ULEBESPCVWBNIF-BYPYZUCNSA-O
19162	113170	7322	-	UBE2D2	E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2321	(R,R)-2,3-Butanediol	-	-	DRUGBANK	DB02418	C4H10O2	small molecule	-	24347-58-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWBTYPJTUOEWEK-ZXZARUISSA-N
19163	113170	7322	-	UBE2D2	E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2321	(R,R)-2,3-Butanediol	-	-	DRUGBANK	DB02418	C4H10O2	small molecule	-	24347-58-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWBTYPJTUOEWEK-ZXZARUISSA-N
19164	113170	7322	-	UBE2D2	E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2321	(R,R)-2,3-Butanediol	-	-	DRUGBANK	DB02418	C4H10O2	small molecule	-	24347-58-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWBTYPJTUOEWEK-ZXZARUISSA-N
19428	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19429	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19430	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19433	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Xu WS (2007)	17694093	181632	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
19570	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2520	1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide	-	-	DRUGBANK	DB02628	C25H38N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JUJIMRZGUBTJRV-NASSWSRMSA-N
19571	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2520	1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide	-	-	DRUGBANK	DB02628	C25H38N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JUJIMRZGUBTJRV-NASSWSRMSA-N
19572	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2520	1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide	-	-	DRUGBANK	DB02628	C25H38N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JUJIMRZGUBTJRV-NASSWSRMSA-N
19691	107582	1163	RP11-307C12.6	CKS1B	CKS1|PNAS-16|PNAS-18|ckshs1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2571	Meta Vanadate	-	-	DRUGBANK	DB02681	O19V7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONZDNYIINYVFKD-UHFFFAOYSA-N
19692	107582	1163	RP11-307C12.6	CKS1B	CKS1|PNAS-16|PNAS-18|ckshs1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2571	Meta Vanadate	-	-	DRUGBANK	DB02681	O19V7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONZDNYIINYVFKD-UHFFFAOYSA-N
19693	107582	1163	RP11-307C12.6	CKS1B	CKS1|PNAS-16|PNAS-18|ckshs1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2571	Meta Vanadate	-	-	DRUGBANK	DB02681	O19V7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONZDNYIINYVFKD-UHFFFAOYSA-N
20059	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2754	Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone	-	-	DRUGBANK	DB02872	C31H34Br2N4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVRYEWOXWGDQHA-FQLXRVMXSA-N
20060	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2754	Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone	-	-	DRUGBANK	DB02872	C31H34Br2N4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVRYEWOXWGDQHA-FQLXRVMXSA-N
20953	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3181	1,4-Diethylene Dioxide	-	-	DRUGBANK	DB03316	C4H8O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYHBNJHYFVUHQT-UHFFFAOYSA-N
20954	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3181	1,4-Diethylene Dioxide	-	-	DRUGBANK	DB03316	C4H8O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYHBNJHYFVUHQT-UHFFFAOYSA-N
20955	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3181	1,4-Diethylene Dioxide	-	-	DRUGBANK	DB03316	C4H8O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYHBNJHYFVUHQT-UHFFFAOYSA-N
21126	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3258	D-Myo-Inositol-1,4,5-Triphosphate	-	-	DRUGBANK	DB03401	C6H15O15P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MMWCIQZXVOZEGG-WZWPATEWSA-N
21127	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3258	D-Myo-Inositol-1,4,5-Triphosphate	-	-	DRUGBANK	DB03401	C6H15O15P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MMWCIQZXVOZEGG-WZWPATEWSA-N
21128	118965	29924	-	EPN1	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3258	D-Myo-Inositol-1,4,5-Triphosphate	-	-	DRUGBANK	DB03401	C6H15O15P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MMWCIQZXVOZEGG-WZWPATEWSA-N
21600	111073	5034	-	P4HB	DSI|ERBA2L|GIT|P4Hbeta|PDI|PDIA1|PHDB|PO4DB|PO4HB|PROHB	9606	Homo sapiens	unknown	target	Horibe T (2001)	11741285	181782	3463	Ribostamycin	Xylostasin|Vistamycin|RIO|Xylostacin|5-Amino-2-Aminomethyl-6-[4,6-Diamino-2-(3,4-Dihydroxy-5-Hydroxymethyl-Tetrahydro-Furan-2-Yloxy)-3-Hydroxy-Cyclohexyloxy]-Tetrahydro-Pyran-3,4-Diol|Ribastamin	-	DRUGBANK	DB03615	C17H34N4O10	small molecule	J01GB10	25546-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NSKGQURZWSPSBC-NLZFXWNVSA-N
22597	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22598	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22599	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3951	Hexatantalum Dodecabromide	-	-	DRUGBANK	DB04119	Br12Ta6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJVLLWDZYINSDB-UHFFFAOYSA-N
22685	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22686	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22687	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22926	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4097	(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid	-	-	DRUGBANK	DB04270	C25H25NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUZIMDSVRIBNNI-DEOSSOPVSA-N
22956	114593	9146	-	HGS	HRS	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
23215	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4189	Debromohymenialdisine	-	-	DRUGBANK	DB04367	C11H10N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
23216	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4189	Debromohymenialdisine	-	-	DRUGBANK	DB04367	C11H10N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
23274	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23499	113164	7316	-	UBC	HMG20	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4278	N-Formylmethionine	-	-	DRUGBANK	DB04464	C6H11NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYUSHNKNPOHWEZ-YFKPBYRVSA-N
24243	116934	23352	RP5-1126H10.1	UBR4	RBAF600|ZUBR1|p600	9606	Homo sapiens	unknown	target	Huh KW (2005)	16061792	145574	4753	HspE7	HPV E7 Peptide Epitope Vaccine|HPV 16 E7/HSP65 Vaccine	-	DRUGBANK	DB04959	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24596	109954	3752	RP4-773A18.7	KCND3	KCND3L|KCND3S|KSHIVB|KV4.3|SCA19|SCA22	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24597	109944	3742	-	KCNA6	HBK2|KV1.6|PPP1R96	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24598	109945	3743	-	KCNA7	HAK6|KV1.7	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24599	109940	3737	RP11-284N8.1	KCNA2	HBK5|HK4|HUKIV|KV1.2|MK2|NGK1|RBK2	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24600	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24601	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24602	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24603	109950	3748	-	KCNC3	KSHIIID|KV3.3|SCA13	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24604	109949	3747	-	KCNC2	KV3.2	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24605	109952	3750	-	KCND1	KV4.1	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24606	109947	3745	-	KCNB1	DRK1|EIEE26|KV2.1|h-DRK1	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24607	109946	3744	-	KCNA10	Kcn1|Kv1.8	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24608	109948	3746	-	KCNC1	KV3.1|KV4|NGK2	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24609	114724	9312	-	KCNB2	KV2.2	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24610	109942	3739	-	KCNA4	HBK4|HK1|HPCN2|HUKII|KCNA4L|KCNA8|KV1.4|PCN2	9606	Homo sapiens	antagonist	target	Judge SI (2006)	16472864	181930	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24611	109953	3751	-	KCND2	KV4.2|RK5	9606	Homo sapiens	antagonist	target	Goodman AD (2013)	23184313	182218	5565	Dalfampridine	Ampyra|4-Pyridylamine|Fampridinum|4-Pyridinamine|N07XX07|P-Aminopyridine|4-AP|EL-970|gamma-Aminopyridine|Dalfampridine|Avitrol|Fampridine-SR|Fampridine|4-Aminopyridine|Fampridina	fampyra|ampyra	DRUGBANK	DB06637	C5H6N2	small molecule	N07XX07	504-24-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NUKYPUAOHBNCPY-UHFFFAOYSA-N
24933	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5727	(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID	-	-	DRUGBANK	DB06908	C24H23ClN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAWOPJKHTZCKMT-QFIPXVFZSA-N
24949	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5745	(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid	-	-	DRUGBANK	DB06926	C18H32O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HNICUWMFWZBIFP-IRQZEAMPSA-N
24994	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5798	(2S)-2-(1H-indol-3-yl)hexanoic acid	-	-	DRUGBANK	DB06980	C14H17NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCBHCHBXRBYJGU-NSHDSACASA-N
24995	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5799	(2S)-2-(1H-indol-3-yl)pentanoic acid	-	-	DRUGBANK	DB06981	C13H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QRCBLBWFQJDFJQ-JTQLQIEISA-N
24996	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5800	(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid	-	-	DRUGBANK	DB06982	C21H30N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWVCKFLATUTBCX-INIZCTEOSA-N
25059	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5871	2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID	-	-	DRUGBANK	DB07053	C24H23F3N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWVYNPULGKGJOS-UHFFFAOYSA-N
25120	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5929	(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid	-	-	DRUGBANK	DB07111	C22H32O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IFRKCNPQVIJFAQ-HBUOOPIGSA-N
25180	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5989	(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid	-	-	DRUGBANK	DB07172	C20H30O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FTAGQROYQYQRHF-CBVHGRPESA-N
25213	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6025	(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid	-	-	DRUGBANK	DB07208	C18H30O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OJFOOCZBVPQYRS-PSDPTOBYSA-N
25214	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6026	(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid	-	-	DRUGBANK	DB07209	C18H30O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLHUENSFQCPBQH-ZBKJIUGYSA-N
25309	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6118	(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid	-	-	DRUGBANK	DB07302	C18H32O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NPDSHTNEKLQQIJ-UINYOVNOSA-N
25455	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6248	1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE	-	-	DRUGBANK	DB07435	C20H16O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GFANZDFKCCJYRF-NSISKUIASA-N
25530	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6320	difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron	-	-	DRUGBANK	DB07509	C22H31BF2N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNKJCLYKBRBEKW-UHFFFAOYSA-N
25574	111661	5688	RP5-1005F21.4	PSMA7	C6|HSPC|RC6-1|XAPC7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6367	ALLN	2-ACETYLAMINO-4-METHYL-PENTANOIC ACID [1-(1-FORMYL-PENTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE|Calpain Inhibitor I|110044-82-1|MG-101|Acetylleucyl-Leucyl-Norleucinal|Calpain Inhibitor I	-	DRUGBANK	DB07558	C20H37N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMYKJLXRRQTBOR-BZSNNMDCSA-N
25656	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6458	1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE	-	-	DRUGBANK	DB07652	C12H15F2O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMMWBGNJJMNAIJ-QJPTWQEYSA-N
25682	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6481	Ragaglitazar	NN-622|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID(-) DRF 2725|Q27088511|DRF-2725|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID|NNC-61-0029|(2S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YLETHOXY)PHENYL]PROPANOIC ACID|1NYX|DRF|(-)-DRF-2725|DRF2725|(S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID|DB07675|RAGAGLITAZAR|GTPL2664|BDBM50109551	-	DRUGBANK	DB07675	C25H25NO5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMUIIGVAWPWQAW-DEOSSOPVSA-N
25728	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6526	3-(5-methoxy-1H-indol-3-yl)propanoic acid	-	-	DRUGBANK	DB07723	C12H13NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZLSZCJIWILJKMR-UHFFFAOYSA-N
25731	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6527	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	-	-	DRUGBANK	DB07724	C19H19NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YMPALHOKRBVHOJ-UHFFFAOYSA-N
25866	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6639	(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid	-	-	DRUGBANK	DB07842	C17H18O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CJMVTSLLWMPEKQ-INIZCTEOSA-N
25900	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6660	2-chloro-5-nitro-N-phenylbenzamide	-	-	DRUGBANK	DB07863	C13H9ClN2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNTSIBUQMRRYIU-UHFFFAOYSA-N
25978	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6745	1H-INDOL-3-YLACETIC ACID	-	-	DRUGBANK	DB07950	C10H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SEOVTRFCIGRIMH-UHFFFAOYSA-N
26140	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6913	(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid	-	-	DRUGBANK	DB08121	C21H18O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZTPJJNNACUQQR-FQEVSTJZSA-N
26215	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6978	(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE	-	-	DRUGBANK	DB08186	C13H13NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYQBFAGILCNRB-BQYQJAHWSA-N
26276	115402	10095	-	ARPC1B	ARC41|p40-ARC|p41-ARC	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7025	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide	-	-	DRUGBANK	DB08235	C16H16N2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACAKNPKRLPMONU-UHFFFAOYSA-N
26283	115402	10095	-	ARPC1B	ARC41|p40-ARC|p41-ARC	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7026	(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one	-	-	DRUGBANK	DB08236	C15H11BrClNO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KEGQNJITMFBVAC-HNNXBMFYSA-N
26290	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7027	2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)	-	-	DRUGBANK	DB08237	C21H22N5O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	COMPKRGNHXOXMN-GVDBMIGSSA-N
26329	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7078	N-(3-AMINOPROPYL)-2-NITROBENZENAMINE	-	-	DRUGBANK	DB08291	C9H13N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVGDDEYVTBKACE-UHFFFAOYSA-N
26341	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7089	3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid	-	-	DRUGBANK	DB08302	C16H15NO5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IRHZCQDCMUWUKV-RAXLEYEMSA-N
26450	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7186	2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID	-	-	DRUGBANK	DB08402	C18H11Cl2N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VNDRRWBKNSHALL-UHFFFAOYSA-N
26475	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7217	(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid	-	-	DRUGBANK	DB08435	C20H28O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VHRUMKCAEVRUBK-XOVNXQNQSA-N
26553	111664	5691	-	PSMB3	HC10-II	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26554	111661	5688	RP5-1005F21.4	PSMA7	C6|HSPC|RC6-1|XAPC7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26555	111660	5687	-	PSMA6	IOTA|PROS27|p27K	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26556	111659	5686	-	PSMA5	PSC5|ZETA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26557	111658	5685	-	PSMA4	HC9|HsT17706|PSC9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26558	111657	5684	-	PSMA3	HC8|PSC3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26559	111656	5683	-	PSMA2	HC3|MU|PMSA2|PSC2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26560	111655	5682	-	PSMA1	HC2|HEL-S-275|NU|PROS30	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26561	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26562	111662	5689	-	PSMB1	HC5|PMSB1|PSC5	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26563	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26564	111665	5692	-	PSMB4	HN3|HsN3|PROS-26|PROS26	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26565	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26566	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7294	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	-	-	DRUGBANK	DB08515	C15H21NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVABESCRHMBHJD-FUQNVFFISA-N
26601	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7338	3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE	-	-	DRUGBANK	DB08560	C19H13F2N3O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GULUFDCOGAXLEP-UHFFFAOYSA-N
26672	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7429	9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE	-	-	DRUGBANK	DB08655	C14H13NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MIGJEXKBUJPKJF-UHFFFAOYSA-N
26761	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7533	(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid	-	-	DRUGBANK	DB08760	C15H13ClO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPBLTMSKPQDJPW-AWEZNQCLSA-N
26955	111662	5689	-	PSMB1	HC5|PMSB1|PSC5	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26956	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26957	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kortuem KM (2013)	23393020	182229	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26958	111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26959	111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26960	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
26983	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	binder	target	Oh CJ (2012)	23056222	182212	7652	Dimethyl fumarate	trans-1,2-Ethylenedicarboxylic acid dimethyl ester|trans-Butenedioic acid dimethyl ester|Tecfidera|(e)-But-2-enedioic acid dimethyl ester|BG-12|1,2-Bis(methoxycarbonyl)-trans-ethylene|Fumaric acid, dimethyl ester|dimethyl (E) butenedioate|Dimethyl trans-ethylenedicarboxylate	tecfidera	DRUGBANK	DB08908	-	small molecule	N07XX09	624-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26985	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	McCurdy AR (2013)	23730498	182252	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
26986	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Lopez-Girona A (2012)	22552008	150660	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
26987	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Ito T (2010)	20223979	126437	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
26995	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Berman HM (2000)	10592235	172122	7659	Aleglitazar	-	-	DRUGBANK	DB08915	C24H23NO5S	small molecule	-	475479-34-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DAYKLWSKQJBGCS-NRFANRHFSA-N
26996	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	agonist	target	Cavender MA (2010)	20653327	182161	7659	Aleglitazar	-	-	DRUGBANK	DB08915	C24H23NO5S	small molecule	-	475479-34-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DAYKLWSKQJBGCS-NRFANRHFSA-N
27698	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Beckers T (2007)	17455259	182004	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27822	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	VanderMolen KM (2011)	21587264	196007	8066	Romidepsin	chromodax|istodax	istodax	DRUGBANK	DB06176	C24H36N4O6S2	small molecule	L01XX39	128517-07-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QDBHDZETSA-N
27866	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Geng L (2006)	17145876	195973	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
28012	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8426	Bivalent ligand 1	Bivalent_ligand_1|SNIPER 11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 11(cIAP1:BE04 --- AR:DHT)	-
28014	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2010)	20369832	125335	8428	Bivalent ligand 2	Bivalent_ligand_2|Compound 4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	107772	1381	-	CRABP1	CRABP|CRABP-I|CRABPI|RBP5	9606	Homo sapiens	target	Standardized BVL Name: Compound 4b(cIAP1:methyl bestatin --- CRABPI/II:ATRA)	-
28016	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang W (2017)	28542609	211389	8428	Bivalent ligand 2	Bivalent_ligand_2|Compound 4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 4b(cIAP1:methyl bestatin --- CRABP-I/II:ATRA)	-
28018	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8427	Bivalent ligand 3	Bivalent_ligand_3|SNIPER 13	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 13(cIAP1:BE04 --- ER:estrone)	-
28020	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8423	Bivalent ligand 4	Bivalent_ligand_4|SNIPER 9	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	111849	5914	-	RARA	NR1B1|RAR	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 9(cIAP1:BE04 --- RAR:Ch55)	-
28022	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2014)	25375378	206180	8422	Bivalent ligand 5	Bivalent_ligand_5|SNIPER(TACC3)-1/SNIPER(TACC3)-2|SNIPER(TACC3)-1|SNIPER(TACC3)-2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(TACC3)-1(cIAP1:bestatin --- TACC3:KHS108)	-
28024	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Henning RK (2016)	26880702	211388	8425	Bivalent ligand 6	Bivalent_ligand_6|CPP-tri_a-PR	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: CPP-tri_a-PR(VHL:HIF1a peptide --- Akt:synthetic peptide)	-
28026	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	degradation	recruited E3 ligase	Sakamoto KM (2003)	14525958	111475	8424	Bivalent ligand 7	Bivalent_ligand_7|Protac-3|Protac 3	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Protac-3(Beta-TrCP:IkBalpha phosphopeptide --- AR:DHT)	-
28028	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Schneekloth JS (2004)	15038727	211349	8421	Bivalent ligand 8	Bivalent_ligand_8|PROTAC 5|Protac-5	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-5 (VHL:HIF1a-polyarginine peptide sequence --- AR:DHT)	-
28030	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited E3 ligase	Schneekloth AR (2008)	18752944	85706	8420	Bivalent ligand 9	Bivalent_ligand_9|PROTAC 14|Protac-14	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 14(MDM2:nutlin-3 --- AR:SARM)	-
28032	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Lee H (2007)	17907127	211396	8450	Bivalent ligand 10	Bivalent_ligand_10|Api-Protac-II	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106699	196	-	AHR	bHLHe76	9606	Homo sapiens	target	Standardized BVL Name: ApiProtac-II(VHL:HIF1a pentapeptide --- AR:apigenin)	-
28034	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Lai AC (2016)	26593377	191787	8449	Bivalent ligand 11	Bivalent_ligand_11|DAS-VHL	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DAS-VHL(VHL:HIF-1alpha hydroxyproline derived small molecule --- c-ABL:dasatinib)	-
28036	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Lai AC (2016)	26593377	191787	8452	Bivalent ligand 12	Bivalent_ligand_12|DAS-CRBN	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DAS-CRBN(CRBN:pomalidomide --- BCR-ABL:dasatinib)	-
28038	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Lai AC (2016)	26593377	191787	8402	Bivalent ligand 43	Bivalent_ligand_43|BOS-CRBN	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: BOS-CRBN(CRBN:pomalidomide --- BCR-ABL:bosutinib)	-
28040	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Demizu Y (2016)	27666635	199362	8451	Bivalent ligand 13	Bivalent_ligand_13|SNIPER(ABL)2,3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ABL)2,3(cIAP1:methyl bestatin --- BCR-ABL:imatinib derivative)	-
28042	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD2:triazolo-diazepine acetamide BET-binding moiety)	-
28044	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD3:triazolo-diazepine acetamide BET-binding moiety)	-
28046	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD4:triazolo-diazepine acetamide BET-binding moiety)	-
28048	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD2:JQ1)	-
28050	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- -BRD3:JQ1)	-
28052	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28054	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Winter GE (2015)	25999370	211411	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28056	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Lu J (2015)	26051217	211422	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28058	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2015)	26075522	211358	8448	Bivalent ligand 16	Bivalent_ligand_16|PROTAC_ERRa	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108405	2101	-	ESRRA	ERR1|ERRa|ERRalpha|ESRL1|NR3B1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC_ERRalpha(VHL:HIF-1alpha hydroxyproline derived small molecule --- ERRa:thiazolidinedione-based compound 29)	-
28060	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	degradation	recruited E3 ligase	Sakamoto KM (2003)	14525958	111475	8447	Bivalent ligand 17	Bivalent_ligand_17|Protac-2|Protac 2	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: Protac-2(Beta-TrCP:IkBalpha phosphopeptide --- ER:estradiol)	-
28062	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8458	Bivalent ligand 18	Bivalent_ligand_18|Protac-B	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: Protac-B(VHL:HIF1a pentapeptide --- ER:estradiol)	-
28064	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Cyrus K (2010)	20572252	211420	8457	Bivalent ligand 19	Bivalent_ligand_19|PROTAC 5	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5(VHL:HIF1a pentapeptide --- ER:estradiol (2 molecules))	-
28066	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Demizu Y (2012)	22277276	211397	8412	Bivalent ligand 20	Bivalent_ligand_20|SNIPER (ER) 5,6,7	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER (ER) 5,6,7(cIAP1:bestatin --- ER:4-hydroxytamoxifen)	-
28068	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2013)	23992566	211367	8413	Bivalent ligand 21	Bivalent_ligand_21|SNIPER(ER)-3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ER)-3(cIAP1:methyl bestatin  --- ER:4-hydroxytamoxifen)	-
28070	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2012)	22658364	211406	8414	Bivalent ligand 22	Bivalent_ligand_22|Compound 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 6(IAP pan-ligand:MV-1  --- CRABP-II:ATRA)	-
28072	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2012)	22658364	211406	8414	Bivalent ligand 22	Bivalent_ligand_22|Compound 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 6(IAP pan-ligand:MV-1  --- CRABP-II: ATRA)	-
28074	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2012)	22658364	211406	8414	Bivalent ligand 22	Bivalent_ligand_22|Compound 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 6(IAP pan-ligand:MV-1 --- CRABP-II: ATRA)	-
28076	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2017)	28154167	211362	8415	Bivalent ligand 23	Bivalent_ligand_23|SNIPER(ER)-87	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ER)-87(XIAP:LCL161 --- ER:4-hydroxytamoxifen)	-
28078	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2017)	28154167	211362	8416	Bivalent ligand 24	Bivalent_ligand_24|SNIPER(BRD4)-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(BRD4)-1(XIAP:LCL161 --- BRD4:JQ1)	-
28080	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2017)	28154167	211362	8417	Bivalent ligand 25	Bivalent_ligand_25|SNIPER(ABL)-38	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ABL)-38(XIAP:LCL161 --- BCR-ABL:dasatinib)	-
28082	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2017)	28154167	211362	8418	Bivalent ligand 26	Bivalent_ligand_26|SNIPER(PDE4)-9	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111167	5141	-	PDE4A	DPDE2|PDE4|PDE46	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(PDE4)-9(XIAP:LCL161 --- PDE4:PDE4 inhibitor)	-
28084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8419	Bivalent ligand 27	Bivalent_ligand_27|Protac-A	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Protac-A(VHL:HIF1a pentapeptide --- AR:DHT)	-
28086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8409	Bivalent ligand 28	Bivalent_ligand_28|Protac-AA	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Protac-AA(VHL:HIF1a pentapeptide+a polyarginine tail and two glycine residues  --- AR:DHT)	-
28088	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Winter GE (2015)	25999370	211411	8410	Bivalent ligand 29	Bivalent_ligand_29|dFKBP-1|dFKBP-2|dFKBP-1/dFKBP-2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: dFKBP-1/dFKBP-2(CRBN:thalidomide --- FKBP12:SLF)	-
28090	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Hines J (2013)	23674677	194582	8460	Bivalent ligand 30	Bivalent_ligand_30|TrkAPPFRS2a|phosphoPROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116031	10818	-	FRS2	FRS2A|FRS2alpha|SNT|SNT-1|SNT1	9606	Homo sapiens	target	Standardized BVL Name: TrkAPPFRS2alpha(VHL:HIF1alpha septapeptide --- FRS2a:phosphorylated TrkA-derived decapeptide sequence)	-
28092	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	degradation	recruited E3 ligase	Sakamoto KM (2001)	11438690	115955	8459	Bivalent ligand 31	Bivalent_ligand_31|Protac-1	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116184	10988	-	METAP2	MAP2|MNPEP|p67|p67eIF2	9606	Homo sapiens	target	Standardized BVL Name: Protac-1(Beta-TrCP:IkBalpha phosphopeptide peptide --- MetAP-2:ovalicin)	-
28094	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang D (2004)	14741260	211348	8432	Bivalent ligand 32	Bivalent_ligand_32|Fu-SMPI	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116184	10988	-	METAP2	MAP2|MNPEP|p67|p67eIF2	9606	Homo sapiens	target	Standardized BVL Name: Fu-SMPI(VHL:HIF-1alpha octapeptide --- MetAP-2:fumagillol)	-
28096	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang D (2004)	14741260	211348	8411	Bivalent ligand 33	Bivalent_ligand_33|E2-SMPI/E2-octa|E2-SMPI|E2-octa	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: E2-SMPI/E2-octa(VHL:HIF-1alpha octapeptide --- ER:estradiol)	-
28098	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bargagna-Mohan P (2005)	15876533	211350	8456	Bivalent ligand 34	Bivalent_ligand_34|E2-penta	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: E2-penta(VHL:HIF-1alpha pentapeptide --- ER:estradiol)	-
28100	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Hines J (2013)	23674677	194582	8455	Bivalent ligand 35	Bivalent_ligand_35|ErbB2PPPI3K|phosphoPROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111313	5295	-	PIK3R1	AGM7|GRB1|IMD36|p85|p85-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: ErbB2PPPI3K(VHL:HIF1alpha septapeptide --- PI3K:ErbB3 peptide)	-
28102	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2015)	26075522	211358	8454	Bivalent ligand 36	Bivalent_ligand_36|PROTAC_RIPK2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC_RIPK2(VHL: HIF-1alpha hydroxyproline derived small molecule --- RIPK2:vandetanib)	-
28104	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Chu TT (2016)	27105281	211375	8453	Bivalent ligand 37	Bivalent_ligand_37|TH006	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: TH006(VHL:HIF1a peptide --- Tau:Beta-tubulin peptide)	-
28106	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	21515062	211395	8404	Bivalent ligand 38	Bivalent_ligand_38|SNIPER 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107772	1381	-	CRABP1	CRABP|CRABP-I|CRABPI|RBP5	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 6(cIAP-I:BE04- --- CRABP-I:ATRA)	-
28108	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Wang X (2016)	27473774	211351	8403	Bivalent ligand 40	Bivalent_ligand_40|PROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110263	4088	-	SMAD3	HSPC193|HsT17436|JV15-2|LDS1C|LDS3|MADH3	9606	Homo sapiens	target	Standardized BVL Name: (VHL:HIF1a peptide --- SMAD3:#8 SMC (EN300-72284))	-
28110	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8436	Bivalent ligand 41	Bivalent_ligand_41|SNIPER(CRABP)-4	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-4(cIAP1:methyl bestatin --- CRABP-II:ATRA)	-
28112	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8401	Bivalent ligand 42	Bivalent_ligand_42|SNIPER(CRABP)-11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	-
28114	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8401	Bivalent ligand 42	Bivalent_ligand_42|SNIPER(CRABP)-11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	-
28116	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8401	Bivalent ligand 42	Bivalent_ligand_42|SNIPER(CRABP)-11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	-
28118	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2015)	26338696	191691	8399	Bivalent ligand 48	Bivalent_ligand_48|compound 1b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	107775	1385	-	CREB1	CREB	9606	Homo sapiens	target	Standardized BVL Name: compound 1b(cIAP1:BE04 --- HaloTag-CREB1)	-
28120	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2015)	26338696	191691	8399	Bivalent ligand 48	Bivalent_ligand_48|compound 1b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	target	Standardized BVL Name: compound 1b(cIAP1:BE04 --- HaloTag-c-jun)	-
28122	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2016)	27236416	205947	8400	Bivalent ligand 49	Bivalent_ligand_49|Compound 4a/4b|Compound 4a|Compound 4b|4a|4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	target	Standardized BVL Name: Compound 4a/4b(IAP pan-ligand:MV1 --- HaloTag-TNFalpha)	-
28124	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2016)	27236416	205947	8400	Bivalent ligand 49	Bivalent_ligand_49|Compound 4a/4b|Compound 4a|Compound 4b|4a|4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	107433	998	RP1-224A6.5	CDC42	CDC42Hs|G25K	9606	Homo sapiens	target	Standardized BVL Name: Compound 4a/4b(IAP pan-ligand:MV1 --- HaloTag-Cdc42)	-
28126	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-ERK1)	-
28128	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-MEK1)	-
28130	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Buhimschi AD (2018)	29851337	211398	8437	Bivalent ligand 51	Bivalent_ligand_51|MT-540|MT-541|MT-781|MT-802	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: MT-540/MT-541/MT-781/ MT-802 (CRBN:pomalidomide --- BTK:Ibrutinib)	-
28132	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang C (2018)	29627725	211374	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: MS4077/MS4078(CRBN:pomalidimide --- ALK:ceritinib)	-
28134	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang X (2018)	29581547	211371	8443	Bivalent ligand 57	Bivalent_ligand_57|ARV-763	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-763 (VHL: :HIF-1alpha hydroxyproline derived small molecule --- BRD4:OTX015)	-
28136	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Robb CM (2017)	28636052	211400	8444	Bivalent ligand 56	Bivalent_ligand_56|PROTAC 3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3(CRBN:thalidomide --- CDK9:aminopyrazole analog)	-
28138	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 1(VHL:Ligand 9 --- EGFR:lapatinib)	-
28140	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8439	Bivalent ligand 53	Bivalent_ligand_53|COMPOUND 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 3(VHL:Ligand 9 --- EGFR:gefitinib)	-
28142	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8442	Bivalent ligand 54	Bivalent_ligand_54|COMPOUND 3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 4(VHL:Ligand 9 --- EGFR:afatinib)	-
28144	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108376	2064	-	ERBB2	CD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1	9606	Homo sapiens	target	Standardized BVL Name: compound 1(VHL:Ligand 9--- HER2:lapatinib)	-
28146	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8441	Bivalent ligand 55	Bivalent_ligand_55|Compound 7	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: compound 7(VHL:Ligand 9 --- c-Met:foretinib)	-
28148	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Jiang Y (2018)	29271628	211419	8405	Bivalent ligand 60	Bivalent_ligand_60|TD-PROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: TD-PROTAC(VHL:HIF1a pentapeptide --- ER: stabilized peptide TD-PERM)	-
28150	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited E3 ligase	Lu M (2018)	29407955	211357	8435	Bivalent ligand 58	Bivalent_ligand_58|Peptide 1	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: Peptide 1(Keap1:peptide Ac-LDPETGEYL-OH --- Tau:b-tubulin derived peptide)	-
28152	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Maniaci C (2017)	29018234	209238	8434	Bivalent ligand 59	Bivalent_ligand_59|CM9|CM10|CM11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: CM9/CM10/CM11(VHL:Ligand 7 --- VHL:Ligand 7)	-
28154	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Winter GE (2017)	28673542	211369	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: dBET6(CRBN:thalidomide --- BRD4:JQ1)	-
28156	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Schiedel M (2018)	28379698	211385	8406	Bivalent ligand 61	Bivalent_ligand_61|SirReal-based PROTAC (12)	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: SirReal-based PROTAC (12)(CRBN:thalidomide --- SIRT2:SirReal3b)	-
28158	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Gadd MS (2017)	28288108	210014	8430	Bivalent ligand 62	Bivalent_ligand_62|AT-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: AT-1 (VHL:modified VH032 --- BRD4:JQ1)	-
28160	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1 (VHL: VHL ligand --- RIPK2: foretinib)	-
28162	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPK14:foretinib)	-
28164	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122928	79837	-	PIP4K2C	PIP5K2C	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- PIP4K2C:foretinib)	-
28166	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MET:foretinib)	-
28168	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- EPHB2:foretinib)	-
28170	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MARK4:foretinib)	-
28172	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108364	2050	-	EPHB4	HTK|MYK1|TYRO11	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- EPHB4:foretinib)	-
28174	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK3:foretinib)	-
28176	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	570722	645745	-	MT1HL1	MT1P2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MT1HL1:foretinib)	-
28178	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110447	4301	-	MLLT4	AF6	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MLLT4:foretinib)	-
28180	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124910	92106	-	OXNAD1	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- OXNAD1:foretinib)	-
28182	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109905	3699	-	ITIH3	H3P	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ITIH3:foretinib)	-
28184	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108336	2021	-	ENDOG	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ENDOG:foretinib)	-
28186	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124429	85014	-	TMEM141	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- TMEM141:foretinib)	-
28188	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108176	1843	-	DUSP1	CL100|HVH1|MKP-1|MKP1|PTPN10	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- DUSP1:foretinib)	-
28190	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122671	79446	-	WDR25	C14orf67	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- WDR25:foretinib)	-
28192	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122312	64834	CGI-88	ELOVL1	Ssc1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ELOVL1:foretinib)	-
28194	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114837	9447	RP11-520H16.3	AIM2	PYHIN4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- AIM2:foretinib)	-
28196	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK2:foretinib)	-
28198	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABL2:foretinib)	-
28200	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAP4K5:foretinib)	-
28202	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113703	7994	-	KAT6A	MOZ|MYST3|RUNXBP2|ZC2HC6A|ZNF220	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- KAT6A:foretinib)	-
28204	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121967	63874	-	ABHD4	ABH4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABHD4:foretinib)	-
28206	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127816	162417	-	NAGS	AGAS|ARGA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- NAGS:foretinib)	-
28208	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121661	57614	-	KIAA1468	HsT3308|HsT885	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- KIAA1468:foretinib)	-
28210	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109833	3621	RP11-8D7.1	ING1	p24ING1c|p33|p33ING1|p33ING1b|p47|p47ING1a	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ING1:foretinib)	-
28212	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109212	2957	-	GTF2A1	TF2A1|TFIIA|TFIIA-42|TFIIAL	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- GTF2A1:foretinib)	-
28214	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABL1:foretinib)	-
28216	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124728	90522	hCG_1785221	YIF1B	FinGER8	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- YIF1B:foretinib)	-
28218	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120295	54957	-	TXNL4B	DLP|Dim2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- TXNL4B:foretinib)	-
28220	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122589	79172	-	CENPO	CENP-O|ICEN-36|MCM21R	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- CENPO:foretinib)	-
28222	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- RIPK2:foretinib)	-
28224	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MET:foretinib)	-
28226	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- EPHB2:foretinib)	-
28228	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121262	56937	RP4-718J7.3	PMEPA1	STAG1|TMEPAI	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- PMEPA1:foretinib)	-
28230	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114138	8569	RP11-49P4.3	MKNK1	MNK1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MKNK1:foretinib)	-
28232	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ABL2:foretinib)	-
28234	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125430	115361	-	GBP4	Mpa2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- GBP4:foretinib)	-
28236	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106832	335	-	APOA1	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- APOA1:foretinib)	-
28238	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108288	1969	-	EPHA2	ARCC2|CTPA|CTPP1|CTRCT6|ECK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- EPHA2:foretinib)	-
28240	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108908	2638	-	GC	DBP|DBP/GC|GRD3|HEL-S-51|VDBG|VDBP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- GC:foretinib)	-
28242	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- CSK:foretinib)	-
28244	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- FER:foretinib)	-
28246	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106682	174	-	AFP	AFPD|FETA|HPAFP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- AFP:foretinib)	-
28248	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117221	23708	-	GSPT2	ERF3B|GST2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- GSPT2:foretinib)	-
28250	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- GSPT1:foretinib)	-
28252	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ZFP91:foretinib)	-
28254	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110607	4501	-	MT1X	MT-1l|MT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MT1X:foretinib)	-
28256	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106953	462	PRO0309	SERPINC1	AT3|AT3D|ATIII|THPH7	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- SERPINC1:foretinib)	-
28258	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ABL1:foretinib)	-
28260	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109905	3699	-	ITIH3	H3P	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ITIH3:foretinib)	-
28262	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122671	79446	-	WDR25	C14orf67	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- WDR25:foretinib)	-
28266	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116278	11097	-	NUPL2	CG1|NLP-1|NLP_1|hCG1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- NUPL2:foretinib)	-
28268	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110018	3818	-	KLKB1	KLK3|PPK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- KLKB1:foretinib)	-
28270	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119555	51465	CGI-76	UBE2J1	HSPC153|HSPC205|HSU93243|NCUBE-1|NCUBE1|UBC6|Ubc6p	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- UBE2J1:foretinib)	-
28272	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115986	10767	RP11-349J5.1	HBS1L	EF-1a|ERFS|HBS1|HSPC276|eRF3c	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- HBS1L:foretinib)	-
28274	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107196	735	-	C9	ARMD15|C9D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- C9:foretinib)	-
28276	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109289	3039	-	HBA1	HBA-T3|HBH	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- HBA1:foretinib)	-
28278	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109906	3700	PRO1851	ITIH4	GP120|H4P|IHRP|ITI-HC4|ITIHL1|PK-120|PK120	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ITIH4:foretinib)	-
28280	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108486	2192	CTA-941F9.7	FBLN1	FBLN|FIBL1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- FBLN1:foretinib)	-
28282	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109295	3045	-	HBD	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- HBD:foretinib)	-
28284	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112978	7123	-	CLEC3B	TN|TNA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- CLEC3B:foretinib)	-
28286	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110238	4060	-	LUM	LDC|SLRR2D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- LUM:foretinib)	-
28288	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111202	5176	PIG35	SERPINF1	EPC-1|OI12|OI6|PEDF	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- SERPINF1:foretinib)	-
28290	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109459	3219	-	HOXB9	HOX-2.5|HOX2|HOX2E	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- HOXB9:foretinib)	-
28292	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107706	1311	-	COMP	EDM1|EPD1|MED|PSACH|THBS5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- COMP:foretinib)	-
28294	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107171	710	-	SERPING1	C1IN|C1INH|C1NH|HAE1|HAE2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- SERPING1:foretinib)	-
28296	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107179	718	-	C3	AHUS5|ARMD9|ASP|C3a|C3b|CPAMD1|HEL-S-62p	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- C3:foretinib)	-
28298	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107181	720	DAMC-258G8.6	C4A	C4|C4A2|C4A3|C4A4|C4A6|C4AD|C4S|CO4|CPAMD2|RG	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- C4A:foretinib)	-
28300	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120295	54957	-	TXNL4B	DLP|Dim2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- TXNL4B:foretinib)	-
28302	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106524	2	-	A2M	A2MD|CPAMD5|FWP007|S863-7	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- A2M:foretinib)	-
28304	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111360	5345	-	SERPINF2	A2AP|AAP|ALPHA-2-PI|API|PLI	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- SERPINF2:foretinib)	-
28306	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109904	3698	RP11-264C14.2	ITIH2	H2P|SHAP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ITIH2:foretinib)	-
28308	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108447	2147	-	F2	PT|RPRGL2|THPH1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- F2:foretinib)	-
28310	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118900	29767	-	TMOD2	N-TMOD|NTMOD	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- TMOD2:foretinib)	-
28312	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115875	10631	RP11-412K4.1	POSTN	OSF-2|OSF2|PDLPOSTN|PN|periostin	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- POSTN:foretinib)	-
28314	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	570722	645745	-	MT1HL1	MT1P2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MT1HL1:foretinib)	-
28316	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110678	4591	-	TRIM37	MUL|POB1|TEF3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- TRIM37:foretinib)	-
28318	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108364	2050	-	EPHB4	HTK|MYK1|TYRO11	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- EPHB4:foretinib)	-
28320	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124429	85014	-	TMEM141	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- TMEM141:foretinib)	-
28324	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115331	10014	-	HDAC5	HD5|NY-CO-9	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- HDAC5:foretinib)	-
28326	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109676	3454	-	IFNAR1	AVP|IFN-alpha-REC|IFNAR|IFNBR|IFRC	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- IFNAR1:foretinib)	-
28328	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117585	26154	-	ABCA12	ARCI4A|ARCI4B|ICR2B|LI2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ABCA12:foretinib)	-
28330	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	937002	100188893	-	TOMM6	OBTP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- TOMM6:foretinib)	-
28332	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114355	8828	-	NRP2	NP2|NPN2|PRO2714|VEGF165R2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- NRP2:foretinib)	-
28334	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MLTK:foretinib)	-
28336	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119311	51124	HSPC039	IER3IP1	MEDS|PRO2309	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- IER3IP1:foretinib)	-
28338	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127816	162417	-	NAGS	AGAS|ARGA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- NAGS:foretinib)	-
28340	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126476	137392	-	FAM92A1	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- FAM92A1:foretinib)	-
28346	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Boselli M (2017)	28972160	211413	8325	IU1-47	Ethanone, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)-|1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone	-	CHEMSPIDER	588237	C19H23ClN2O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VXQIPRWKLACSKZ-UHFFFAOYSA-N
28347	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Zhao C (2017)	28086217	211382	8326	ZnPT, zinc pyrithione	Pyrithione zinc|Zinc bis(pyridine-2-thiolate 1-oxide)|2295|R953O2RHZ5|2-Pyridinethiol, 1-oxide, zinc salt (2:1)|Zinc bis(2-pyridinethiolate 1-oxide)	-	CHEMSPIDER	24255	C10H8N2O2S2Zn	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTPSWLRZXRHDNX-UHFFFAOYSA-L
28348	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Zhao C (2017)	28086217	211382	8326	ZnPT, zinc pyrithione	Pyrithione zinc|Zinc bis(pyridine-2-thiolate 1-oxide)|2295|R953O2RHZ5|2-Pyridinethiol, 1-oxide, zinc salt (2:1)|Zinc bis(2-pyridinethiolate 1-oxide)	-	CHEMSPIDER	24255	C10H8N2O2S2Zn	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTPSWLRZXRHDNX-UHFFFAOYSA-L
28349	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28350	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28351	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28352	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28353	113867	8239	RP5-1172N10.4	USP9X	DFFRX|FAF|FAM|MRX99	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28354	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28355	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28356	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28357	132019	377630	-	USP17L2	DUB-3|DUB3|USP17	9606	Homo sapiens	inhibitor	target	Wu Y (2017)	28198361	199410	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28358	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	8330	GW7647	GW7647|Propanoic acid, 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methyl-|2-[(4-{2-[(4-Cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid	-	CHEMSPIDER	2637470	C29H46N2O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PKNYXWMTHFMHKD-UHFFFAOYSA-N
28359	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	8330	GW7647	GW7647|Propanoic acid, 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methyl-|2-[(4-{2-[(4-Cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid	-	CHEMSPIDER	2637470	C29H46N2O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PKNYXWMTHFMHKD-UHFFFAOYSA-N
28360	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	1088	Pimozide	Orap|Halomonth|Pimozida|Pimozide|Opiran|Pimozidum|Neoperidole	orap|pms-pimozide|orap tab 10m	DRUGBANK	DB01100	C28H29F2N3O	small molecule	N05AG02	2062-78-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YVUQSNJEYSNKRX-UHFFFAOYSA-N
28361	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	1088	Pimozide	Orap|Halomonth|Pimozida|Pimozide|Opiran|Pimozidum|Neoperidole	orap|pms-pimozide|orap tab 10m	DRUGBANK	DB01100	C28H29F2N3O	small molecule	N05AG02	2062-78-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YVUQSNJEYSNKRX-UHFFFAOYSA-N
28362	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Dexheimer TS (2014)	25229643	211355	8331	ML323	ML323|N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine|4-Pyrimidinamine, 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-|2-(2-Isopropylphenyl)-5-methyl-N-[4-(1H-1,2,3-triazol-1-yl)benzyl]-4-pyrimidinamine	-	CHEMSPIDER	30646677	C23H24N6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VUIRVWPJNKZOSS-UHFFFAOYSA-N
28363	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Dexheimer TS (2014)	25229643	211355	8331	ML323	ML323|N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine|4-Pyrimidinamine, 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-|2-(2-Isopropylphenyl)-5-methyl-N-[4-(1H-1,2,3-triazol-1-yl)benzyl]-4-pyrimidinamine	-	CHEMSPIDER	30646677	C23H24N6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VUIRVWPJNKZOSS-UHFFFAOYSA-N
28364	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Pozhidaeva A (2017)	29056420	211409	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28365	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Pozhidaeva A (2017)	29056420	211409	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28366	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Tian Z (2014)	24319254	211391	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28367	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Tian Z (2014)	24319254	211391	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28368	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	An T (2017)	28216017	211393	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
28369	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2016)	27264969	211363	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28370	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2016)	27264969	211363	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28371	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Lee BH (2010)	20829789	211386	8335	IU1	1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone|Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-	-	CHEMSPIDER	588197	C18H21FN2O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JUWDSDKJBMFLHE-UHFFFAOYSA-N
28372	113194	7347	RP11-173B14.3	UCHL3	UCH-L3	9606	Homo sapiens	inhibitor	target	Liu Y (2003)	14522054	211347	8336	TCID	TCID|compound 6 [PMID: 17948018]|4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione|1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro-	-	CHEMSPIDER	2011008	C9H2Cl4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IDLAOWFFKWRNHB-UHFFFAOYSA-N
28373	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Liu Y (2003)	14522054	211347	8337	C30	1H-Indole-2,3-dione, 5-chloro-1-[(2,5-dichlorophenyl)methyl]-, 3-(O-acetyloxime), (3Z)-|(3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one|LDN57444|LDN-57444|LDN 57444|	-	CHEMSPIDER	21395767	C17H11Cl3N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OPQRFPHLZZPCCH-PGMHBOJBSA-N
28374	113194	7347	RP11-173B14.3	UCHL3	UCH-L3	9606	Homo sapiens	inhibitor	target	Liu Y (2003)	14522054	211347	8337	C30	1H-Indole-2,3-dione, 5-chloro-1-[(2,5-dichlorophenyl)methyl]-, 3-(O-acetyloxime), (3Z)-|(3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one|LDN57444|LDN-57444|LDN 57444|	-	CHEMSPIDER	21395767	C17H11Cl3N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OPQRFPHLZZPCCH-PGMHBOJBSA-N
28375	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Reverdy C (2012)	22520753	131069	8338	HBX 19818	2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-|N-{3-[Benzyl(methyl)amino]propyl}-9-chloro-5,6,7,8-tetrahydro-2-acridinecarboxamide	-	CHEMSPIDER	30814431	C25H28ClN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZCALMLVWZSQGGR-UHFFFAOYSA-N
28376	115508	10213	-	PSMD14	PAD1|POH1|RPN11	9606	Homo sapiens	inhibitor	target	Li J (2017)	28244987	211399	8339	Capzimin	8-Sulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]-3-quinolinecarboxamide|3-Quinolinecarboxamide, 8-mercapto-N-[2-(2-thiazolyl)ethyl]-	-	CHEMSPIDER	61729338	C15H13N3OS2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MYNGHZGMRXNEEH-UHFFFAOYSA-N
28377	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28378	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Yang Y (2007)	17909057	211378	8340	PYR-41	PYR-41|Ethyl 4-{(4Z)-4-[(5-nitro-2-furyl)methylene]-3,5-dioxo-1-pyrazolidinyl}benzoate|Benzoic acid, 4-[(4Z)-4-[(5-nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]-, ethyl ester	-	CHEMSPIDER	4492747	C17H13N3O7	small molecule	-	418805-02-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ARGIPZKQJGFSGQ-LCYFTJDESA-N
28379	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	An H (2015)	28717502	211368	8341	ABP-A3	N-(3-Ethynylphenyl)-5'-O-sulfamoyladenosine|Adenosine, 5'-O-(aminosulfonyl)-N-(3-ethynylphenyl)-	-	CHEMSPIDER	57643654	C18H18N6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZNFQRSVDZCPTR-SCFUHWHPSA-N
28380	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Xu GW (2010)	20075161	211377	8342	PYZD-4409	3,5-Pyrazolidinedione, 1-(3-chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-, (4E)-|(4E)-1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furyl)methylene]-3,5-pyrazolidinedione	-	CHEMSPIDER	29394292	C14H7ClFN3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MSYMKEYWUWVZQY-RMKNXTFCSA-N
28381	113182	7334	-	UBE2N	HEL-S-71|UBC13|UBCHBEN; UBC13|UbcH-ben|UbcH13	9606	Homo sapiens	inhibitor	target	Hodge CD (2015)	25909880	186087	8343	NSC697923	2-[(4-Methylphenyl)sulfonyl]-5-nitrofuran|Furan, 2-[(4-methylphenyl)sulfonyl]-5-nitro-	-	CHEMSPIDER	349633	C11H9NO5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GAUHIPWCDXOLCZ-UHFFFAOYSA-N
28382	113182	7334	-	UBE2N	HEL-S-71|UBC13|UBCHBEN; UBC13|UbcH-ben|UbcH13	9606	Homo sapiens	inhibitor	target	Hodge CD (2015)	25909880	186087	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28383	107432	997	-	CDC34	E2-CDC34|UBC3|UBCH3|UBE2R1	9606	Homo sapiens	inhibitor	target	Ceccarelli DF (2011)	21683433	124394	8345	CC0651	L-Arabinonic acid, 4,5-dideoxy-5-(3',5'-dichloro[1,1'-biphenyl]-4-yl)-4-[(2-methoxyacetyl)amino]-|4,5-Dideoxy-5-(3',5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-Arabinonic Acid|(2R,3S,4S)-5-(3',5'-Dichloro-[1,1'-biphenyl]-4-yl)-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid|4,5-Dideoxy-5-(3',5'-dichloro-4-biphenylyl)-4-[(methoxyacetyl)amino]-L-arabinonic acid	-	CHEMSPIDER	26329232	C20H21Cl2NO6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NTCBTNCWNRCBGX-YTQUADARSA-N
28384	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Uehara T (2017)	28437394	211360	8346	E7820	3-Cyano-N-(3-cyano-4-methyl-1H-indole-7-yl)benzensulfonamide|Benzenesulfonamide, 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)-|3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide|E-7820	-	CHEMSPIDER	170592	C17H12N4O2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LWGUASZLXHYWIV-UHFFFAOYSA-N
28385	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Uehara T (2017)	28437394	211360	8347	indisulam	indisulam|N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide|8199|WJ98J3NM90|1,4-Benzenedisulfonamide, N~1~-(3-chloro-1H-indol-7-yl)-|N-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide	-	CHEMSPIDER	187608	C14H12ClN3O4S2	small molecule	-	165668-41-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SETFNECMODOHTO-UHFFFAOYSA-N
28386	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Uehara T (2017)	28437394	211360	8348	Chlorsulfaquinoxaline	O0408QB48D|Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-|4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide|NSC-339004	-	CHEMSPIDER	65384	C14H11ClN4O2S	small molecule	-	97919-22-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CTSNHMQGVWXIEG-UHFFFAOYSA-N
28388	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Han T (2017)	28302793	209322	8349	tasisulam	Tasisulam|1YC4W9MSLJ|9030|Benzamide, N-[(5-bromo-2-thienyl)sulfonyl]-2,4-dichloro-|N-[(5-Bromo-2-thienyl)sulfonyl]-2,4-dichlorobenzamide|5-Bromo-N-(2,4-dichlorobenzoyl)-2-thiophenesulfonamide	-	CHEMSPIDER	8335746	C11H6BrCl2NO3S2	small molecule	-	519055-62-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WWONFUQGBVOKOF-UHFFFAOYSA-N
28389	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Han T (2017)	28302793	209322	8348	Chlorsulfaquinoxaline	O0408QB48D|Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-|4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide|NSC-339004	-	CHEMSPIDER	65384	C14H11ClN4O2S	small molecule	-	97919-22-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CTSNHMQGVWXIEG-UHFFFAOYSA-N
28390	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	inhibitor	target	Bennett J (2015)	25974391	190207	8350	compound 34	compound 34 [PMID: 25974391]|Benzenesulfonamide, N-[2,3-dihydro-6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl]-3,4-dimethoxy-|3,4-Dimethoxy-N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]benzenesulfonamide	-	CHEMSPIDER	29068819	C24H25N3O7S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KNVIUMWNYXDULF-UHFFFAOYSA-N
28391	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Yoshizaki Y (2017)	28638054	207216	8351	chlorophyllin sodium copper salt	Cuprate(3-), [18-carboxy-20-(carboxymethyl)-8-ethenyl-13-ethyl-3,7,12,17-tetramethyl-21H,23H-porphine-2-propanoato(5-)-kappaN~21~,kappaN~23~]-, sodium (1:3)|Trisodium [18-(2-carboxyethyl)-20-(carboxymethyl)-7-ethyl-3,8,13,17-tetramethyl-12-vinyl-2-porphyrincarboxylato(5-)-kappa~2~N,N']cuprate(3-)	-	CHEMSPIDER	32035047	C34H29CuN4Na3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QDAAKTODRKELHM-PJABRTMHSA-I
28392	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Yoshizaki Y (2017)	28638054	207216	8352	bonaphton	1,2-Naphthalenedione, 6-bromo-|6-Bromo-1,2-naphthalenedione	-	CHEMSPIDER	21868	C10H5BrO2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MXWZRRPNVLCHMY-UHFFFAOYSA-N
28393	114503	9039	-	UBA3	NAE2|UBE1C|hUBA3	9606	Homo sapiens	inhibitor	target	Soucy TA (2009)	19360080	209255	8353	Pevonedistat	MLN4924|MLN 4924|[(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl]methyl sulfamate|Pevonedistat|[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate|S3AZD8D215|9605|MLN4924	-	CHEMSPIDER	17625129	C21H25N5O4S	small molecule	-	905579-51-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MPUQHZXIXSTTDU-QXGSTGNESA-N
28394	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Soucy TA (2009)	19360080	209255	8353	Pevonedistat	MLN4924|MLN 4924|[(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl]methyl sulfamate|Pevonedistat|[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate|S3AZD8D215|9605|MLN4924	-	CHEMSPIDER	17625129	C21H25N5O4S	small molecule	-	905579-51-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MPUQHZXIXSTTDU-QXGSTGNESA-N
28395	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	modulator	target	Matyskiela ME (2018)	28425720	207534	8354	Iberdomide, compound 6	Iberdomide|8V66F27X44|10632|UNII:8V66F27X44|CC-220|2,6-Piperidinedione, 3-[1,3-dihydro-4-[[4-(4-morpholinylmethyl)phenyl]methoxy]-1-oxo-2H-isoindol-2-yl]-, (3S)-|(3S)-3-(4-{[4-(4-Morpholinylmethyl)benzyl]oxy}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-piperidinedione	-	CHEMSPIDER	52085251	C25H27N3O5	small molecule	-	1323403-33-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IXZOHGPZAQLIBH-NRFANRHFSA-N
28398	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24900784	211364	8355	RO5353	Spiro[pyrrolidine-3,6'-[6H]thieno[3,2-b]pyrrole]-5-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-4',5'-dihydro-5'-oxo-, (2S,3R,4R,5R)-|(2S,3R,4R,5R)-N-(4-Carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide	-	CHEMSPIDER	31135029	C29H29Cl2FN4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UOVSZRTTWLJPHE-HNXAPSNLSA-N
28399	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24900784	211364	8356	RO2468	(2S,3R,4S,5R)-N-(4-Carbamoyl-2-methoxyphenyl)-6'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-2'-oxo-1',2'-dihydrospiro[pyrrolidine-3,3'-pyrrolo[3,2-c]pyridine]-5-carboxamide	-	CHEMSPIDER	31135031	C30H30Cl2FN5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CGCOPBXAGSCZNX-FNQJWKMRSA-N
28400	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Tan G (2017)	28549433	207226	8357	JS-K	Ethyl 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-1-piperazinecarboxylate|1-Piperazinecarboxylic acid, 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-, ethyl ester	-	CHEMSPIDER	24684273	C13H16N6O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DNJRNBYZLPKSHV-XMHGGMMESA-N
28401	112373	6478	-	SIAH2	hSiah2	9606	Homo sapiens	inhibitor	target	Tan G (2017)	28549433	207226	8357	JS-K	Ethyl 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-1-piperazinecarboxylate|1-Piperazinecarboxylic acid, 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-, ethyl ester	-	CHEMSPIDER	24684273	C13H16N6O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DNJRNBYZLPKSHV-XMHGGMMESA-N
28402	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	modulator	target	Ramkumar KM (2013)	23826874	211390	8358	Pterostilbene	4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]phenol|Phenol, 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-|26R60S6A5I|3,5-dimethoxy-4'-hydroxystilbene|Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-|4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol|4-Stilbenol, 3',5'-dimethoxy-, (E)-|3,5-Dimethoxy-4'-hydroxy-trans-stilbene|3',5'-Dimethoxy-4-stilbenol|Pterostilbene|4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol|(E)-pterostilbene	-	CHEMSPIDER	4445042	C16H16O3	small molecule	-	537-42-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VLEUZFDZJKSGMX-ONEGZZNKSA-N
28403	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	modulator	target	Huang HL (2012)	22389469	211417	8359	Oridonin	Oridonin|(1alpha,5beta,6beta,7alpha,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-Tetrahydroxy-7,20-epoxykaur-16-en-15-one	-	CHEMSPIDER	23326877	C20H28O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SDHTXBWLVGWJFT-BAFGBBEMSA-N
28404	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	modulator	target	Matyskiela ME (2016)	27338790	199780	8360	CC-885	2,6-Piperidinedione, 3-[5-[[[(1Z)-[(3-chloro-4-methylphenyl)amino]hydroxymethylene]amino]methyl]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-|N-(3-Chloro-4-methylphenyl)-N'-{[2-(2,6-dioxo-3-piperidinyl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl]methyl}carbamimidic acid	-	CHEMSPIDER	59718492	C22H21ClN4O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEVCIHTTTYVCC-UHFFFAOYSA-N
28405	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	modulator	target	Han T (2017)	28302793	209322	8347	indisulam	indisulam|N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide|8199|WJ98J3NM90|1,4-Benzenedisulfonamide, N~1~-(3-chloro-1H-indol-7-yl)-|N-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide	-	CHEMSPIDER	187608	C14H12ClN3O4S2	small molecule	-	165668-41-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SETFNECMODOHTO-UHFFFAOYSA-N
28406	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Nepal M (2012)	22760073	211412	8361	Bavachinin	2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one|4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-|2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-on|2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one|2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydro-4H-chromen-4-one|Bavachinin A	-	CHEMSPIDER	109499	C21H22O4	small molecule	-	19879-30-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VOCGSQHKPZSIKB-UHFFFAOYSA-N
28407	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	22369643	131566	8362	(4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE	(4r)-4-Hydroxy-1-[(3-Methylisoxazol-5-Yl)acetyl]-N-[4-(1,3-Oxazol-5-Yl)benzyl]-L-Prolinamide|2-Pyrrolidinecarboxamide, 4-hydroxy-1-[2-(3-methyl-5-isoxazolyl)acetyl]-N-[[4-(5-oxazolyl)phenyl]methyl]-, (2S,4R)-|(4R)-4-Hydroxy-1-[(3-methyl-1,2-oxazol-5-yl)acetyl]-N-[4-(1,3-oxazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	31133666	C21H22N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HFCLIEBJTGJKSV-AEFFLSMTSA-N
28408	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Galdeano C (2014)	25166285	167549	8363	(2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	L-Prolinamide, N-acetyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-|N-Acetyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	35035176	C24H32N4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFVIEZBZIUKYOG-SVFBPWRDSA-N
28409	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Soares P (2018)	28853884	211366	8364	VH298	-	-	CHEMSPIDER	58804244	C54H66N10O8S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GYJMGEJLYDLYLJ-IUVJQGSXSA-N
28410	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Frost J (2016)	27811928	211370	8364	VH298	-	-	CHEMSPIDER	58804244	C54H66N10O8S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GYJMGEJLYDLYLJ-IUVJQGSXSA-N
28411	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	23065727	148591	8365	(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide	(2s,4r)-1-(2-Chlorophenyl)carbonyl-N-[(4-Chlorophenyl)methyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide|2-Pyrrolidinecarboxamide, 1-(2-chlorobenzoyl)-N-[(4-chlorophenyl)methyl]-4-hydroxy-, (2S,4R)-|(4R)-1-(2-Chlorobenzoyl)-N-(4-chlorobenzyl)-4-hydroxy-L-prolinamide	-	CHEMSPIDER	35034462	C19H18Cl2N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	POSPLUDREYFAQC-PBHICJAKSA-N
28412	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	23065727	148591	8366	(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	(2s,4r)-1-(3-Amino-2-Methylbenzoyl)-4-Hydroxy-N-(4-(4-Methylthiazol-5-Yl)benzyl)pyrrolidine-2-Carboxamide|2-Pyrrolidinecarboxamide, 1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-|(4R)-1-(3-Amino-2-methylbenzoyl)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	34258861	C24H26N4O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AFUSGLDYQSDIEU-NQIIRXRSSA-N
28413	122265	64750	-	SMURF2	-	9606	Homo sapiens	inhibitor	target	Mund T (2014)	25385595	170019	8367	heclin	2-Propenamide, N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)-, (2E)-|(2E)-N-(4-Acetylphenyl)-3-(5-ethyl-2-furyl)acrylamide	-	CHEMSPIDER	5783743	C17H17NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SPTWXRJNCFIDRQ-ZHACJKMWSA-N
28414	110811	4734	PIG53	NEDD4	NEDD4-1|RPF1	9606	Homo sapiens	inhibitor	target	Mund T (2014)	25385595	170019	8367	heclin	2-Propenamide, N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)-, (2E)-|(2E)-N-(4-Acetylphenyl)-3-(5-ethyl-2-furyl)acrylamide	-	CHEMSPIDER	5783743	C17H17NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SPTWXRJNCFIDRQ-ZHACJKMWSA-N
28415	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Mund T (2014)	25385595	170019	8367	heclin	2-Propenamide, N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)-, (2E)-|(2E)-N-(4-Acetylphenyl)-3-(5-ethyl-2-furyl)acrylamide	-	CHEMSPIDER	5783743	C17H17NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SPTWXRJNCFIDRQ-ZHACJKMWSA-N
28416	123747	83737	-	ITCH	ADMFD|AIF4|AIP4|NAPP1|dJ468O1.1	9606	Homo sapiens	inhibitor	target	Rossi M (2014)	24787015	211402	1230	Clomipramine	Clomipraminum|3-Chloroimipramine|Monochlorimipramine|3-(3-chloro-10,11-dihydro-5H-Dibenzo[b,F]azepin-5-yl)-N,N-dimethyl-1-propanamine|Clomipramine|Clomipramina|g 34586|Chlorimipramine|3-(3-CHLORO-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine	gen-clomipramine - tab 50mg|pm	DRUGBANK	DB01242	C19H23ClN2	small molecule	N06AA04	303-49-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GDLIGKIOYRNHDA-UHFFFAOYSA-N
28417	113185	7337	-	UBE3A	ANCR|AS|E6-AP|EPVE6AP|HPVE6A	9606	Homo sapiens	inhibitor	target	Rossi M (2014)	24787015	211402	1230	Clomipramine	Clomipraminum|3-Chloroimipramine|Monochlorimipramine|3-(3-chloro-10,11-dihydro-5H-Dibenzo[b,F]azepin-5-yl)-N,N-dimethyl-1-propanamine|Clomipramine|Clomipramina|g 34586|Chlorimipramine|3-(3-CHLORO-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine	gen-clomipramine - tab 50mg|pm	DRUGBANK	DB01242	C19H23ClN2	small molecule	N06AA04	303-49-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GDLIGKIOYRNHDA-UHFFFAOYSA-N
28418	107427	991	-	CDC20	CDC20A|bA276H19.3|p55CDC	9606	Homo sapiens	inhibitor	target	Sackton KL (2014)	25156254	168402	8368	apcin	Carbamic acid, N-[2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester|2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]carbamate	-	CHEMSPIDER	2108234	C13H14Cl3N7O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZEXHXVOGJFGTRX-UHFFFAOYSA-N
28419	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Chan CH (2013)	23911321	209204	8369	SZL-P1-41	SZL-P1-41|4H-1-Benzopyran-4-one, 3-(2-benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-|3-(1,3-benzothiazol-2-yl)-6-ethyl-7-hydroxy-8-(piperidin-1-ylmethyl)-4H-chromen-4-one|3-(1,3-Benzothiazol-2-yl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-chromen-4-one	-	CHEMSPIDER	1079391	C24H24N2O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JKIXLEKBXHMXTN-UHFFFAOYSA-N
28420	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	inhibitor	target	Liu YQ (2015)	26474281	191844	8370	6-OAP	(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-butenoate|2-Butenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester, (2Z)-	-	CHEMSPIDER	21246838	C20H26O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KUPPZVXLWANEJJ-UXPPPGSFSA-N
28421	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Chen Q (2008)	18305219	211404	8371	Compound A	4-({[3-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylbutyl]amino}methyl)-N,N-dimethylaniline|2H-Pyran-4-propanamine, N-[[4-(dimethylamino)phenyl]methyl]tetrahydro-2,2-dimethyl-gamma-(phenylmethyl)-	-	CHEMSPIDER	2647927	C26H38N2O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BHBPSUYHNUDVJC-UHFFFAOYSA-N
28422	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Wu L (2012)	23261596	150374	8372	SKP2E3LI-C5	(4-Bromo-2-{(Z)-[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)acetic acid|Acetic acid, 2-[4-bromo-2-[(Z)-[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]-	-	CHEMSPIDER	4666286	C18H13BrN2O4S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IYCJJVVXEHZJHE-CHHVJCJISA-N
28423	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Wu L (2012)	23261596	150374	8373	SKP2E3LI-C16	[4-({3-[2-(4-Chlorophenyl)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}methyl)phenoxy]acetic acid|Acetic acid, 2-[4-[[3-[2-(4-chlorophenyl)-2-oxoethyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]-	-	CHEMSPIDER	2186424	C20H14ClNO6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PROYNXVBTGKBIR-UHFFFAOYSA-N
28424	117657	26273	-	FBXO3	FBA|FBX3	9606	Homo sapiens	inhibitor	target	Chen BB (2013)	23542741	211387	8374	BC-1215	N,N'-Bis[4-(2-pyridinyl)benzyl]-1,2-ethanediamine|1,2-Ethanediamine, N~1~,N~2~-bis[[4-(2-pyridinyl)phenyl]methyl]-	-	CHEMSPIDER	35293716	C26H26N4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IXEPQJQQSLMESJ-UHFFFAOYSA-N
28425	117355	25827	-	FBXL2	FBL2|FBL3	9606	Homo sapiens	activator	target	Chen BB (2013)	23928698	194960	8375	BC-1258	1,2-Ethanediamine, N~1~,N~2~-bis[[4-(2-thiazolyl)phenyl]methyl]-|N,N'-Bis[4-(1,3-thiazol-2-yl)benzyl]-1,2-ethanediamine	-	CHEMSPIDER	35293709	C22H22N4S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FRTSLZJCGAFSET-UHFFFAOYSA-N
28426	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	inhibitor	target	Nakajima H (2008)	18275844	211408	8376	GS143	Benzoic acid, 4-[(4E)-4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-|4-[(4E)-3-Benzyl-4-{[5-(2-fluorophenyl)-2-furyl]methylene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid	-	CHEMSPIDER	35517727	C28H19FN2O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IZPMWFSVTDOCDI-HAVVHWLPSA-N
28427	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Rico-Bautista E (2010)	21182779	211354	8377	SMIP004	N-(4-Butyl-2-methylphenyl)acetamide|Acetamide, N-(4-butyl-2-methylphenyl)-	-	CHEMSPIDER	2029029	C13H19NO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZFVMECVBUGMWIX-UHFFFAOYSA-N
28429	107116	648	RP11-573G6.1	BMI1	FLVI2/BMI1|PCGF4|RNF51	9606	Homo sapiens	inhibitor	target	Alchanati I (2009)	19956605	124271	8378	PRT4165	2-Pyridin-3-ylmethylene-indan-1,3-dione|PRT-4165|J625FJL5DX|2-(Pyridin-3-ylmethylene)-1H-indene-1,3(2H)-dione|1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-|2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione	-	CHEMSPIDER	180156	C15H9NO2	small molecule	-	31083-55-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OMHZFEWYVFWVLI-UHFFFAOYSA-N
28430	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Tovar C (2013)	23400593	211352	8379	RG7112	RO-5045337|Q8MI0X869M|{(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}{4-[3-(methylsulfonyl)propyl]-1-piperazinyl}methanone|Methanone, [(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]-	-	CHEMSPIDER	28189760	C38H48Cl2N4O4S	small molecule	-	939981-39-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBGKPEROWUKSBK-QPPIDDCLSA-N
28431	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ding Q (2013)	23808545	211356	8380	RG7388	idasanutlin|4-{[(3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-D-prolyl]amino}-3-methoxybenzoic acid|Benzoic acid, 4-[[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxy-	-	CHEMSPIDER	30831264	C31H29Cl2F2N3O4	small molecule	-	1229705-06-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TVTXCJFHQKSQQM-LJQIRTBHSA-N
28432	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Bill KL (2016)	26475335	211379	8381	SAR405838	8570LZ3RCA|SAR-405838|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	30811498	C29H34Cl2FN3O3	small molecule	-	1303607-60-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IDKAKZRYYDCJDU-HBMMIIHUSA-N
28433	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Shangary S (2008)	18316739	208243	8382	MI-219	(2'R,3R,4'R,5'R)-6-Chloro-4'-(3-chlorophenyl)-N-[(3S)-3,4-dihydroxybutyl]-5-fluoro-2'-(2-methyl-2-propanyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chlorophenyl)-N-[(3S)-3,4-dihydroxybutyl]-2'-(1,1-dimethylethyl)-5-fluoro-1,2-dihydro-2-oxo-, (2'R,3R,4'R,5'R)-	-	CHEMSPIDER	59695355	C26H30Cl2FN3O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KUMSTKUNLHZBEQ-MWFJYFKBSA-N
28434	121411	57154	-	SMURF1	-	9606	Homo sapiens	inhibitor	target	Cao Y (2014)	24828823	164649	8383	A01	Methanone, [4-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]-|(4-{[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinyl)[4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone	-	CHEMSPIDER	11146868	C22H20ClF3N4O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QFYLTUDRXBNZFQ-UHFFFAOYSA-N
28435	121411	57154	-	SMURF1	-	9606	Homo sapiens	inhibitor	target	Cao Y (2014)	24828823	164649	8384	A17	1-Ethyl-6-fluoro-4-oxo-7-[4-(3-phenylpropanoyl)-1-piperazinyl]-1,4-dihydro-3-quinolinecarboxylic acid|3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(1-oxo-3-phenylpropyl)-1-piperazinyl]-	-	CHEMSPIDER	10931084	C25H26FN3O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WSMQLUAQZNPXFD-UHFFFAOYSA-N
28437	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	An H (2015)	28717502	211368	8341	ABP-A3	N-(3-Ethynylphenyl)-5'-O-sulfamoyladenosine|Adenosine, 5'-O-(aminosulfonyl)-N-(3-ethynylphenyl)-	-	CHEMSPIDER	57643654	C18H18N6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZNFQRSVDZCPTR-SCFUHWHPSA-N
28438	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Adams J (1999)	10363983	211346	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
28439	114214	8665	-	EIF3F	EIF3S5|eIF3-p47	9606	Homo sapiens	unknown	target	Wang RE (2011)	21798748	146659	4044	Quercetin	3,5,7,3',4'-Pentahydroxyflavone	-	DRUGBANK	DB04216	C15H10O7	small molecule	-	117-39-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	REFJWTPEDVJJIY-UHFFFAOYSA-N
28440	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Tang Y (2017)	28807012	211380	8385	HBX 41,108	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile|9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 7-chloro-9-oxo-	-	CHEMSPIDER	17225370	C13H3ClN4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BIGPXXAUSQLTQR-UHFFFAOYSA-N
28441	113221	7375	-	USP4	UNP|Unph	9606	Homo sapiens	inhibitor	target	Okada K (2013)	23791076	211401	8386	Vialinin A	Vialinin A|Benzeneacetic acid, 4,4'',5',6'-tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl ester|4,4'',5',6'-Tetrahydroxy-1,1':4',1''-terphenyl-2',3'-diyl bis(phenylacetate)	-	CHEMSPIDER	9737907	C34H26O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NOJUKCRPSUMHQQ-UHFFFAOYSA-N
28442	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Okada K (2013)	23791076	211401	8386	Vialinin A	Vialinin A|Benzeneacetic acid, 4,4'',5',6'-tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl ester|4,4'',5',6'-Tetrahydroxy-1,1':4',1''-terphenyl-2',3'-diyl bis(phenylacetate)	-	CHEMSPIDER	9737907	C34H26O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NOJUKCRPSUMHQQ-UHFFFAOYSA-N
28443	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Okada K (2013)	23791076	211401	8386	Vialinin A	Vialinin A|Benzeneacetic acid, 4,4'',5',6'-tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl ester|4,4'',5',6'-Tetrahydroxy-1,1':4',1''-terphenyl-2',3'-diyl bis(phenylacetate)	-	CHEMSPIDER	9737907	C34H26O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NOJUKCRPSUMHQQ-UHFFFAOYSA-N
28444	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Yan C (2018)	29462615	211405	8387	NSC 632839	4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, hydrochloride (1:1)|3,5-Bis(4-methylbenzylidene)piperidin-4-one hydrochloride (1:1)|3,5-Bis(4-methylbenzylidene)-4-piperidinone hydrochloride (1:1)	-	CHEMSPIDER	324262	C21H22ClNO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZOKZLTXPTLIWOJ-UHFFFAOYSA-N
28445	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Chen X (2018)	29098502	211361	8388	Pyrithione cadmium	Cadmium bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, cadmium salt (2:1)	-	CHEMSPIDER	178371	C10H8CdN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YSWAWAYOPDDQJN-UHFFFAOYSA-N
28446	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Chen X (2018)	29098502	211361	8388	Pyrithione cadmium	Cadmium bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, cadmium salt (2:1)	-	CHEMSPIDER	178371	C10H8CdN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YSWAWAYOPDDQJN-UHFFFAOYSA-N
28447	115508	10213	-	PSMD14	PAD1|POH1|RPN11	9606	Homo sapiens	inhibitor	target	Song Y (2017)	28581522	211353	2270	1,10-Phenanthroline	-	-	DRUGBANK	DB02365	C12H8N2	small molecule	-	66-71-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DGEZNRSVGBDHLK-UHFFFAOYSA-N
28448	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28449	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28450	113221	7375	-	USP4	UNP|Unph	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28451	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28452	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28453	114555	9101	-	USP8	HumORF8|SPG59|UBPY	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28454	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28455	116077	10868	-	USP20	LSFR3A|VDU2|hVDU2	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28456	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28457	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28458	125956	126119	SBBI54	JOSD2	-	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28459	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28460	113194	7347	RP11-173B14.3	UCHL3	UCH-L3	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28461	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28462	125819	123228	FKSG8	SENP8	DEN1|NEDP1|PRSC2	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28463	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24977961	211418	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
28464	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24977961	211418	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
28465	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Coughlin K (2014)	24727327	211407	8390	RA-9	(3E,5E)-3,5-Bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (3E,5E)-|(3E,5E)-3,5-bis(4-nitrobenzylidene)piperidin-4-one|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (E,E)-|NSC685125|(3E,5E)-3,5-Bis[(4-nitrophenyl)methylidene]piperidin-4-one	-	CHEMSPIDER	4579802	C19H15N3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YUYPWAMLWZVHAE-KAVGSWPWSA-N
28466	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Coughlin K (2014)	24727327	211407	8390	RA-9	(3E,5E)-3,5-Bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (3E,5E)-|(3E,5E)-3,5-bis(4-nitrobenzylidene)piperidin-4-one|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (E,E)-|NSC685125|(3E,5E)-3,5-Bis[(4-nitrophenyl)methylidene]piperidin-4-one	-	CHEMSPIDER	4579802	C19H15N3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YUYPWAMLWZVHAE-KAVGSWPWSA-N
28467	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Tian X (2011)	21133675	211365	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28468	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Zhou B (2013)	23696216	211384	8391	AC17	1H-Indole-2-sulfonic acid, 5-[2-(aminocarbonyl)hydrazinylidene]-2,3,5,6-tetrahydro-1-methyl-6-oxo-, sodium salt (1:1)|Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate	-	CHEMSPIDER	21161414	C10H11N4NaO5S	small molecule	-	51460-26-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HLFCZZKCHVSOAP-UHFFFAOYSA-M
28469	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Zhou B (2013)	23696216	211384	8391	AC17	1H-Indole-2-sulfonic acid, 5-[2-(aminocarbonyl)hydrazinylidene]-2,3,5,6-tetrahydro-1-methyl-6-oxo-, sodium salt (1:1)|Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate	-	CHEMSPIDER	21161414	C10H11N4NaO5S	small molecule	-	51460-26-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HLFCZZKCHVSOAP-UHFFFAOYSA-M
28470	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28471	116914	23326	-	USP22	USP3L	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28472	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28473	114555	9101	-	USP8	HumORF8|SPG59|UBPY	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28474	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28475	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28476	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Swords RT (2010)	20203261	211410	8353	Pevonedistat	MLN4924|MLN 4924|[(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl]methyl sulfamate|Pevonedistat|[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate|S3AZD8D215|9605|MLN4924	-	CHEMSPIDER	17625129	C21H25N5O4S	small molecule	-	905579-51-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MPUQHZXIXSTTDU-QXGSTGNESA-N
28477	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Kawamura S (2014)	24524217	211421	8393	compund 4a	N~2~-Acetyl-N~4~-{4-(benzyloxy)-3-[(benzyloxy)methyl]butyl}-N~1~-{(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}-L-aspartamide|L-Aspartamide, N~2~-acetyl-N~1~-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-N~4~-[4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]butyl]-	-	CHEMSPIDER	34237644	C40H58BN3O7	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OGQMVFMKRZZEEH-JVCXTPEFSA-N
28478	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Kawamura S (2014)	24524217	211421	8394	compound 11a	L-Aspartamide, N~2~-acetyl-N~1~-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-N~4~-[4-(phenylmethoxy)butyl]-|N~2~-Acetyl-N~4~-[4-(benzyloxy)butyl]-N~1~-{(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}-L-aspartamide	-	CHEMSPIDER	34237654	C32H50BN3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ODIWGDQSSAWSIL-GKWCIWIWSA-N
28479	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Kawamura S (2014)	24524217	211421	8393	compund 4a	N~2~-Acetyl-N~4~-{4-(benzyloxy)-3-[(benzyloxy)methyl]butyl}-N~1~-{(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}-L-aspartamide|L-Aspartamide, N~2~-acetyl-N~1~-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-N~4~-[4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]butyl]-	-	CHEMSPIDER	34237644	C40H58BN3O7	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OGQMVFMKRZZEEH-JVCXTPEFSA-N
28480	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Kawamura S (2014)	24524217	211421	8394	compound 11a	L-Aspartamide, N~2~-acetyl-N~1~-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-N~4~-[4-(phenylmethoxy)butyl]-|N~2~-Acetyl-N~4~-[4-(benzyloxy)butyl]-N~1~-{(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}-L-aspartamide	-	CHEMSPIDER	34237654	C32H50BN3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ODIWGDQSSAWSIL-GKWCIWIWSA-N
28481	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Kawamura S (2014)	24524217	211421	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
28483	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Sodji Q (2014)	25240614	211381	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
28487	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Roccaro AM (2010)	20110419	211392	8397	Oprozomib	ONX 0912|MZ37792Y8J|9597|Oprozomib|D-erythro-3-Pentulose, 4,5-anhydro-1,2-dideoxy-4-C-methyl-2-[[O-methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-L-seryl]amino]-1-phenyl-|4,5-Anhydro-1,2-dideoxy-4-methyl-2-({O-methyl-N-[(2-methyl-1,3-thiazol-5-yl)carbonyl]-L-seryl-O-methyl-L-seryl}amino)-1-phenyl-D-erythro-pent-3-ulose	-	CHEMSPIDER	28528375	C25H32N4O7S	small molecule	-	935888-69-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SWZXEVABPLUDIO-WSZYKNRRSA-N
28488	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Roccaro AM (2010)	20110419	211392	8397	Oprozomib	ONX 0912|MZ37792Y8J|9597|Oprozomib|D-erythro-3-Pentulose, 4,5-anhydro-1,2-dideoxy-4-C-methyl-2-[[O-methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-L-seryl]amino]-1-phenyl-|4,5-Anhydro-1,2-dideoxy-4-methyl-2-({O-methyl-N-[(2-methyl-1,3-thiazol-5-yl)carbonyl]-L-seryl-O-methyl-L-seryl}amino)-1-phenyl-D-erythro-pent-3-ulose	-	CHEMSPIDER	28528375	C25H32N4O7S	small molecule	-	935888-69-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SWZXEVABPLUDIO-WSZYKNRRSA-N
28490	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24912524	211415	8578	CuPT	Copper(2+) bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, copper(2+) salt (2:1)	-	CHEMSPIDER	76402	C10H8CuN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XDUPUJNNHFTMQS-UHFFFAOYSA-N
28491	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24912524	211415	8578	CuPT	Copper(2+) bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, copper(2+) salt (2:1)	-	CHEMSPIDER	76402	C10H8CuN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XDUPUJNNHFTMQS-UHFFFAOYSA-N
28492	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Yan C (2018)	29462615	211405	8337	C30	1H-Indole-2,3-dione, 5-chloro-1-[(2,5-dichlorophenyl)methyl]-, 3-(O-acetyloxime), (3Z)-|(3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one|LDN57444|LDN-57444|LDN 57444|	-	CHEMSPIDER	21395767	C17H11Cl3N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OPQRFPHLZZPCCH-PGMHBOJBSA-N
28493	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Davis MI (2016)	27681596	198526	8596	ML364	Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-|2-{[(4-Methylphenyl)sulfonyl]amino}-N-(4-phenyl-1,3-thiazol-2-yl)-4-(trifluoromethyl)benzamide	-	CHEMSPIDER	30917317	C24H18F3N3O3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QZUGMNXETPARLI-UHFFFAOYSA-N
28494	107427	991	-	CDC20	CDC20A|bA276H19.3|p55CDC	9606	Homo sapiens	inhibitor	target	Zeng X (2010)	20951947	139860	8463	TAMe	TAME|tosyl-arginine methyl ester|tosyl-L-arginine methyl ester|Ts-Arg-OMe|p-toluensulfonyl-L-arginine methyl ester|Nalpha-p-tosyl-L-arginine methyl ester|methyl N2-(p-tosyl)-L-argininate|methyl N2-(p-toluenenesulfonyl)-L-argininate|methyl N2-[(p-tolyl)sulphonyl]-L-argininate|N2-(p-tolylsulfonyl)-L-arginine methyl ester|methyl N2-[(4-methylphenyl)sulfonyl]-L-argininate	-	CHEBI	62167	C14H22N4O4S	small molecule	-	1784-03-08	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FKMJXALNHKIDOD-LBPRGKRZSA-N
28495	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	inhibitor	target	Zeng X (2010)	20951947	139860	8463	TAMe	TAME|tosyl-arginine methyl ester|tosyl-L-arginine methyl ester|Ts-Arg-OMe|p-toluensulfonyl-L-arginine methyl ester|Nalpha-p-tosyl-L-arginine methyl ester|methyl N2-(p-tosyl)-L-argininate|methyl N2-(p-toluenenesulfonyl)-L-argininate|methyl N2-[(p-tolyl)sulphonyl]-L-argininate|N2-(p-tolylsulfonyl)-L-arginine methyl ester|methyl N2-[(4-methylphenyl)sulfonyl]-L-argininate	-	CHEBI	62167	C14H22N4O4S	small molecule	-	1784-03-08	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FKMJXALNHKIDOD-LBPRGKRZSA-N
28496	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Lamberto I (2017)	29056421	211372	8464	9QD	XL188|N-[3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-4-oxoquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide|N-[3-({4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl}methyl)-4-oxo-3,4-dihydroquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide|SCHEMBL20856972|(R)-N-(3-((4-Hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)-3-(4-methylpiperazin-1-yl)propanamide|2305045-76-3	-	PDB	9QD	C32H42N6O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QLBYDWATOPNXBG-XMMPIXPASA-N
28498	107076	604	-	BCL6	BCL5|BCL6A|LAZ3|ZBTB27|ZNF51	9606	Homo sapiens	inhibitor	target	Cardenas MG (2016)	27482887	212314	8583	FX1	FX1|3-Thiazolidinepropanoic acid, 5-(5-chloro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-, (5Z)-|3-[(5Z)-5-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoic acid	-	CHEMSPIDER	28612733	C14H9ClN2O4S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VISHSGZPGQKEFX-KHPPLWFESA-N
28499	107076	604	-	BCL6	BCL5|BCL6A|LAZ3|ZBTB27|ZNF51	9606	Homo sapiens	inhibitor	target	Cerchietti LC (2010)	20385364	218656	8462	79-6	(2R)-2-[(5Z)-5-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanedioic acid|(2R)-2-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]succinic acid|Butanedioic acid, 2-[(5Z)-5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]-, (2R)-	-	CHEMSPIDER	25057870	C15H9BrN2O6S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QGNRETMYLHRUBB-OZEWEUHLSA-N
28500	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	inhibitor	target	Anchoori RK (2013)	24332045	163442	8573	RA190	(3Z,5Z)-1-[(2S)-2-Amino-3-phenylpropanoyl]-3,5-bis(3,4-dichlorobenzylidene)-4-piperidinone hydrochloride (1:1)|4-Piperidinone, 1-[(2S)-2-amino-1-oxo-3-phenylpropyl]-3,5-bis[(3,4-dichlorophenyl)methylene]-, (3Z,5Z)-, hydrochloride (1:1)	-	CHEMSPIDER	67896519	C28H23Cl5N2O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UMWXLEVUBFNYIK-VCCJZKHWSA-N
28501	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	activator	target	Sievers QL (2018)	30385546	212829	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
28502	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Zhou B (2018)	30473361	212965	6528	TBHQ	2-tert-butylbenzene-1,4-diol|tert-butylhydroquinone|MTBHQ|MX4375000|1-t-Butyl-1,4-dihydroxybenzene|1948-33-0|Hydroquinone, tert-butyl-|1,4-Benzenediol, 2-(1,1-dimethylethyl)-|2-(2-Methyl-2-propanyl)-1,4-benzenediol	-	DRUGBANK	DB07726	C10H14O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	tBHQ is shown to disrupt the interaction between KEAP1 and NFE2L2 preventing ubiquitination by KEAP1	BGNXCDMCOKJUMV-UHFFFAOYSA-N
28503	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Zhou B (2018)	30473361	212965	315	Floxuridine	beta-5-Fluoro-2'-deoxyuridine|Floxuridin|1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil|Floxuridinum|5-Fluorouracil deoxyriboside|5-Fluorodeoxyuridine|Deoxyfluorouridine|5-Fluoro-2-desoxyuridine|Floxiridina|Fluoruridine Deoxyribose|2'-Deoxy-5-fluorouridine|FdU|Floxuridine|Fluorodeoxyuridine|5-Fluorouracil 2'-deoxyriboside|5FDU|1beta-D-2'-Deoxyribofuranosyl-5-flurouracil|1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil|FUDR	floxuridine	DRUGBANK	DB00322	C9H11FN2O5	small molecule	-	50-91-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	F-dUrd is shown to disrupt the interaction between KEAP1 and NFE2L2 preventing ubiquitination by KEAP1	ODKNJVUHOIMIIZ-RRKCRQDMSA-N
28504	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Mills EL (2018)	29590092	212817	8585	4-octyl Itaconate	Butanedioic acid, 2-methylene-, 4-octyl ester|2-Methylene-4-(octyloxy)-4-oxobutanoic acid	-	CHEMSPIDER	68003917	C13H22O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KBASUIDPDITQHT-UHFFFAOYSA-N
28505	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhou Y (2018)	29670376	212575	8591	Butein	Butein|Chalcone, 2',3,4,4'-tetrahydroxy- (7CI,8CI)|2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one|(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one|2056928|4WVS5M0LGF|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one[	-	CHEMSPIDER	4444634	C15H12O5	small molecule	-	487-52-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AYMYWHCQALZEGT-ORCRQEGFSA-N
28506	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Ward SJ (2018)	30228188	213502	1192	Mitoxantrone	Mitoxantrona|Mitoxantronum|Mitoxantrone|1,4-DIHYDROXY-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-anthracenedione	mitoxantrone injection|mitoxan	DRUGBANK	DB01204	C22H28N4O6	small molecule	L01DB07	65271-80-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KKZJGLLVHKMTCM-UHFFFAOYSA-N
28507	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Mori T (2018)	29358579	213956	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
28508	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Ito T (2010)	20223979	126437	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
28509	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Chuang SJ (2018)	29449607	213957	344	Tioguanine	2-Amino-6-mercaptopurine|2-Amino-6-purinethiol|Tioguanin|2-aminopurine-6-thiol|6-TG|Tioguanine|2-amino-1,9-Dihydropurine-6-thione|2-Amino-1,7-dihydro-6H-purine-6-thione|6-Thioguanine|Thioguanine|2-Aminopurin-6-thiol|6-Mercaptoguanine|2-Amino 6mp|2-amino-1H-purine-6(7H)-thione|Tioguanina|ThG|TG|Tioguaninum|2-Amino-6-merkaptopurin|2-Aminopurine-6(1H)-thione|6-Mercapto-2-aminopurine|6-thioguanine	tabloid|lanvis	DRUGBANK	DB00352	C5H5N5S	small molecule	L01BB03	154-42-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WYWHKKSPHMUBEB-UHFFFAOYSA-N
28510	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	inhibitor	target	Wong DPW (2018)	30273379	213993	8600	andrographolide	[1R-[1a[E(S*)],4ab,5a,6a,8aa]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone|3a,14,15,18-Tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic Acid g-Lactone|Chuanxinlian|Kalmegh|(3E)-4-Hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone|2(3H)-Furanone, 3-[2-[(1R,4aS,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E)-|(3E)-4-Hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylendecahydro-1-naphthalenyl]ethyliden}dihydro-2(3H)-furanon|(3E)-4-hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one|(3E)-4-Hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl]ethylidene}dihydrofuran-2(3H)-one	-	CHEMSPIDER	16735664	C20H30O5	small molecule	-	5508-58-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BOJKULTULYSRAS-FNTFRYDESA-N
28511	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Gavory G (2018)	29200206	213952	8576	3-[4-(Aminomethyl)phenyl]-6-{[4-hydroxy-1-(4,4,4-trifluoro-3-phenylbutanoyl)-4-piperidinyl]methyl}-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one	7H-Pyrazolo[4,3-d]pyrimidin-7-one, 3-[4-(aminomethyl)phenyl]-2,6-dihydro-6-[[4-hydroxy-1-(4,4,4-trifluoro-1-oxo-3-phenylbutyl)-4-piperidinyl]methyl]-2-methyl-|3-[4-(Aminomethyl)phenyl]-6-{[4-hydroxy-1-(4,4,4-trifluoro-3-phenylbutanoyl)-4-piperidinyl]methyl}-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one	-	CHEMSPIDER	65324406	C29H31F3N6O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	PDB ID 5N9T	RLPQYKGBXQQARM-UHFFFAOYSA-N
28512	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Gavory G (2018)	29200206	213952	8575	7-bromanyl-3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	7-Bromo-3-{[4-hydroxy-1-(3-phenylbutanoyl)-4-piperidinyl]methyl}thieno[3,2-d]pyrimidin-4(3H)-one|Thieno[3,2-d]pyrimidin-4(3H)-one, 7-bromo-3-[[4-hydroxy-1-(1-oxo-3-phenylbutyl)-4-piperidinyl]methyl]-	-	CHEMSPIDER	65324407	C22H24BrN3O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	PDB ID 5N9R	NRRXSEFLOFZNSO-UHFFFAOYSA-N
28513	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Barghout SH (2019)	29884901	214627	8580	TAK-243	V9GGV0YCDI|TAK-243|Sulfamic acid, [(1R,2R,3S,4R)-2,3-dihydroxy-4-[[2-[3-[(trifluoromethyl)thio]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl ester|{(1R,2R,3S,4R)-2,3-Dihydroxy-4-[(2-{3-[(trifluoromethyl)sulfanyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)amino]cyclopentyl}methyl sulfamate	-	CHEMSPIDER	58828173	C19H20F3N5O5S2	small molecule	-	1450833-55-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KJDAGXLMHXUAGV-DGWLBADLSA-N
28514	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8620	4,4'-Dimethyl-2,2',5,5'-biphenyltetrol	4,4'-dimethyl[1,1'-biphenyl]-2,2',5,5'-tetrol|4,4'-Dimethyl-2,2',5,5'-biphenyltetrol|[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-	-	CHEMSPIDER	191018	C14H14O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 1 (NSC2805); Targets WWP2, WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	DSVRCBOSZSZMRX-UHFFFAOYSA-N
28515	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8588	N-[(Z)-2-(2,5-Dihydroxyphenyl)vinyl]formamide	N-[(Z)-2-(2,5-Dihydroxyphenyl)vinyl]formamide|Formamide, N-[(Z)-2-(2,5-dihydroxyphenyl)ethenyl]-	-	CHEMSPIDER	4578295	C9H9NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 2 (NSC650438); Targets WWP2, WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	SIHZWGODIRRSRA-ARJAWSKDSA-N
28516	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8595	4-Nitro-7-[(1-oxido-2-pyridinyl)sulfanyl]-2,1,3-benzoxadiazole	4-Nitro-7-[(1-oxido-2-pyridinyl)sulfanyl]-2,1,3-benzoxadiazole|2,1,3-Benzoxadiazole, 4-nitro-7-[(1-oxido-2-pyridinyl)thio]-	-	CHEMSPIDER	277406	C11H6N4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 7 (NSC228155); Increased inhibition towards WWP2 and Nedd4 over WWP1; Showed no STD NMR experiment signal but could not be excluded as a binder to WWP2 HECT catalytic domain.	ICCFXXDUYSPKOL-UHFFFAOYSA-N
28517	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8605	3,5-Bis(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid	3,5-Bis(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid|Benzoic acid, 3,5-bis(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-	-	CHEMSPIDER	209302	C15H8N2O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 12 (NSC44750); Targets WWP2, WWP1 and Nedd4; No positive binding results in STD NMR experiment likley due to solubility issues.	RCBGGBMZYJSLJE-UHFFFAOYSA-N
28518	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8611	2-(3-Nitrophenyl)-3-nitrosoimidazo[1,2-a]pyrimidine	2-(3-Nitro-phenyl)-3-nitroso-imidazo[1,2-a]pyrimidine|2-(3-Nitrophenyl)-3-nitrosoimidazo[1,2-a]pyrimidine|Imidazo[1,2-a]pyrimidine, 2-(3-nitrophenyl)-3-nitroso-	-	CHEMSPIDER	301406	C12H7N5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 16 (NSC369066); Increased inhibition towards WWP2 over WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	QPWJAIUKYMKWGA-UHFFFAOYSA-N
28519	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8597	7,8-Dimethyl-10-(2-Acetoxyethyl)Isoalloxazine	7,8-Dimethyl-10-(2-Acetoxyethyl)Isoalloxazine|Benzo[g]pteridine-2,4(3H,10H)-dione, 10-[2-(acetyloxy)ethyl]-7,8-dimethyl-|2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl acetate	-	CHEMSPIDER	21222	C16H16N4O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 17 (NSC3064); Increased inhibition towards WWP2 over WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	PVRDHKBVCDWVPD-UHFFFAOYSA-N
28520	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8610	S-[(2Z)-2-Amino-2-{[(6,6-dimethylbicyclo[3.1.1]hept-2-yl)methyl]imino}ethyl] hydrogen sulfurothioate	Thiosulfuric acid (H_2_S_2_O_3_), S-[(2Z)-2-amino-2-[[(6,6-dimethylbicyclo[3.1.1]hept-2-yl)methyl]imino]ethyl] ester|S-[(2Z)-2-Amino-2-{[(6,6-dimethylbicyclo[3.1.1]hept-2-yl)methyl]imino}ethyl] hydrogen sulfurothioate	-	CHEMSPIDER	268720	C12H22N2O3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 18 (NSC194308); Increased inhibition towards WWP2 over WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	VOOABHIKMGRJFC-UHFFFAOYSA-N
28521	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8592	4-[(4-Methylphenyl)sulfinyl]-7-nitro-2,1,3-benzoxadiazole	4-[(4-Methylphenyl)sulfinyl]-7-nitro-2,1,3-benzoxadiazole|2,1,3-Benzoxadiazole, 4-[(4-methylphenyl)sulfinyl]-7-nitro-	-	CHEMSPIDER	277401	C13H9N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 19 (NSC228150); Increased inhibition towards WWP2 and Nedd4 over WWP1; No positive binding results in STD NMR experiment likley due to solubility issues.	FRBRHPUZSWIODD-UHFFFAOYSA-N
28522	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8604	10-(2-Methoxyethyl)-3-phenylbenzo[g]pteridine-2,4(3H,10H)-dione	10-(2-Methoxyethyl)-3-phenylbenzo[g]pteridine-2,4(3H,10H)-dione|Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl-	-	CHEMSPIDER	287083	C19H16N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 20 (NSC288387); Increased inhibition towards WWP2 over WWP1 and Nedd4; Ligandbased NMR confirmed binding of compound to the WWP2 HECT catalytic domain.	VBIVGEJXWFOZBG-UHFFFAOYSA-N
28523	116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	inhibitor	target	Watt JE (2018)	30207403	215624	8601	Methylium, tris(4-(diethylamino)phenyl)-	Methylium, tris(4-(diethylamino)phenyl)-|Methylium, tris(p-(diethylamino)phenyl)-|Ethanaminium, N-(4-(bis(4-(diethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-ethyl-|Ethanaminium, N-[4-[bis[4-(diethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-|4-{Bis[4-(diethylamino)phenyl]methylene}-N,N-diethyl-2,5-cyclohexadien-1-iminium	-	CHEMSPIDER	16065	C31H42N3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Compound 21 (NSC8675); Increased inhibition towards WWP2 over WWP1 and Nedd4; No positive binding results in STD NMR experiment likley due to solubility issues.	VYYRJGKHDDYUGK-UHFFFAOYSA-N
28524	124238	84749	-	USP30	-	9606	Homo sapiens	inhibitor	target	Kluge AF (2018)	29935771	216210	8598	Na-(Cyclohexylcarbonyl)-N-{5-[(2-methyl-2-propanyl)sulfamoyl]-1-naphthyl}-L-phenylalaninamide	Benzenepropanamide, alpha-[(cyclohexylcarbonyl)amino]-N-[5-[[(1,1-dimethylethyl)amino]sulfonyl]-1-naphthalenyl]-, (alphaS)-|Nalpha-(Cyclohexylcarbonyl)-N-{5-[(2-methyl-2-propanyl)sulfamoyl]-1-naphthyl}-L-phenylalaninamide	-	CHEMSPIDER	72380119	C30H37N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DQXORJHBZHLLTE-SANMLTNESA-N
28525	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Lu J (2016)	27764791	216708	8381	SAR405838	8570LZ3RCA|SAR-405838|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	30811498	C29H34Cl2FN3O3	small molecule	-	1303607-60-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IDKAKZRYYDCJDU-HBMMIIHUSA-N
28529	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Sznarkowska A (2019)	30603043	218393	2193	Protoporphyrin Ix	protoporphyrin IX|protoporphyrin|553-12-8|Ooporphyrin|Protoporpyrin IX|ppIX|Porphyrinogen IX|Protoporphyrin IX disodium|Kammerers prophyrin	-	DRUGBANK	DB02285	C34H33N4O4	small molecule	-	553-12-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	PpIX ablates TAp73/MDM2, TAp73/MDMX and TAp73/Itch complexes	-
28530	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Sznarkowska A (2019)	30603043	218393	2193	Protoporphyrin Ix	protoporphyrin IX|protoporphyrin|553-12-8|Ooporphyrin|Protoporpyrin IX|ppIX|Porphyrinogen IX|Protoporphyrin IX disodium|Kammerers prophyrin	-	DRUGBANK	DB02285	C34H33N4O4	small molecule	-	553-12-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	PpIX ablates TAp73/MDM2, TAp73/MDMX and TAp73/Itch complexes	-
28531	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Potts BC (2011)	21247382	218714	8396	Marizomib	(1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-3-hydroxy-5-methyl-6-oxa-2-azabicyclo[3.2.0]hept-2-en-7-one|(1R,4R,5S)-4-(2-Chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-yl(hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione|(-)-salinosporamide A|marizomib|6-Oxa-2-azabicyclo[3.2.0]heptane-3,7-dione, 4-(2-chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-ylhydroxymethyl]-5-methyl-, (1R,4R,5S)-|Salinosporamide A|9205|703P9YDP7F|BDBM50398608	-	CHEMSPIDER	9522473	C15H20ClNO4	small molecule	-	437742-34-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NGWSFRIPKNWYAO-SHTIJGAHSA-N
28532	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2011)	21343295	220329	8618	MNS	MNS|3,4-Methylenedioxy-.beta.-nitrostyrene|3,4-Methylenedioxy-beta-nitrostyrene|1,3-Benzodioxole, 5- (2-nitroethenyl)-|5-[(E)-2-Nitrovinyl]-1,3-benzodioxole|1,3-Benzodioxole, 5-[(E)-2-nitroethenyl]-|Syk Inhibitor III|MFCD00014575|WL5270000|5-(2-NITRO-VINYL)-BENZO(1,3)DIOXOLE	-	CHEMSPIDER	585303	C9H7NO4	small molecule	-	1485-00-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KFLWBZPSJQPRDD-ONEGZZNKSA-N
28533	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2011)	21383145	220330	8574	DBeQ	2,4-dibenzylaminoquinazoline|2,4-Quinazolinediamine, N~2~,N~4~-bis(phenylmethyl)-|DBeQ|N2,N4-dibenzylquinazoline-2,4-diamine|N,N'-Dibenzyl-2,4-quinazolinediamine|MFCD03691820|JRF 12	-	CHEMSPIDER	589082	C22H20N4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QAIMUUJJAJBPCL-UHFFFAOYSA-N
28534	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Magnaghi P (2013)	23892893	220331	8581	NMS-873	Pyridine, 3-[3-(cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-|NMS-873|MFCD28009371|3-[3-Cyclopentylsulfanyl-5-(4'-methanesulfonyl-2-methylbiphenyl-4-yloxymethyl)-[1,2,4]triazol-4-yl]-pyridine|3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-pyridine|3-[3-(Cyclopentylsulfanyl)-5-({[2-methyl-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-4H-1,2,4-triazol-4-yl]pyridine	-	CHEMSPIDER	29398603	C27H28N4O3S2	small molecule	-	1418013-75-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UJGTUKMAJVCBIS-UHFFFAOYSA-N
28535	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	modulator	target	Hagner PR (2015)	26002965	185946	8616	avadomide	2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-|3-(5-Amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione|3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione|10599|28DZS29F59|UNII:28DZS29F59|avadomide	-	CHEMSPIDER	35521266	C14H14N4O3	small molecule	-	1015474-32-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	CC-122 recruits Aiolos and Ikaros and induces their ubiquitination by the CRL4CRBN E3 ubiquitin ligase complex	RSNPAKAFCAAMBH-UHFFFAOYSA-N
28536	118895	29761	-	USP25	USP21	9606	Homo sapiens	inhibitor	target	Wrigley JD (2017)	29131570	207318	8579	AZ1	Ethanol, 2-[[[5-bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]-|2-[(5-Bromo-2-{[4-fluoro-3-(trifluoromethyl)benzyl]oxy}benzyl)amino]ethanol	-	CHEMSPIDER	78316098	C17H16BrF4NO2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ITHSFXDGKQYOED-UHFFFAOYSA-N
28537	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Wrigley JD (2017)	29131570	207318	8579	AZ1	Ethanol, 2-[[[5-bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]-|2-[(5-Bromo-2-{[4-fluoro-3-(trifluoromethyl)benzyl]oxy}benzyl)amino]ethanol	-	CHEMSPIDER	78316098	C17H16BrF4NO2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ITHSFXDGKQYOED-UHFFFAOYSA-N
28540	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Lain S (2008)	18455128	78113	8621	Tenovin-1	N-[4-({[(4-tert-butylbenzoyl)amino]carbothioyl}amino)phenyl]acetamide|Tenovin-1|N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide|Benzamide, N-[[[4-(acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-|N-[(4-Acetamidophenyl)carbamothioyl]-4-(2-methyl-2-propanyl)benzamide|N-[(4-acetamidoanilino)-sulfanylidenemethyl]-4-tert-butylbenzamide|BIQ6AID2B7	-	CHEMSPIDER	875023	C20H23N3O2S	small molecule	-	380315-80-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	Tenovin-1 protects against MDM2-mediated p53 degradation and inhibits the protein deacetylating activities of SirT1 and SirT2.	WOWJIWFCOPZFGV-UHFFFAOYSA-N
28541	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Thompson T (2010)	20406950	223663	8606	Serdemetan	Serdemetan|1,4-Benzenediamine, N~1~-[2-(1H-indol-3-yl)ethyl]-N~4~-4-pyridinyl-|N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine|9161|ID6YB4W3V8	-	CHEMSPIDER	9784341	C21H20N4	small molecule	-	881202-45-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CEGSUKYESLWKJP-UHFFFAOYSA-N
28542	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Wang H (2011)	21075910	223664	8619	7-(4-Methyl-1-piperazinyl)-4-nitro-2,1,3-benzoxadiazole 1-oxide	7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide|2,1,3-Benzoxadiazole, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide|7-(4-Methyl-1-piperazinyl)-4-nitro-2,1,3-benzoxadiazole 1-oxide	-	CHEMSPIDER	38890	C11H13N5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MWFZDJLPWDCQIL-UHFFFAOYSA-N
28543	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Issaeva N (2004)	15558054	144968	8582	RITA (NSC 652287)	(Furan-2,5-diyldithiene-5,2-diyl)dimethanol|2-Thiophenemethanol, 5,5'-(2,5-furandiyl)bis-|RITA (NSC 652287)|(2,5-Furandiyldi-5,2-thienediyl)dimethanol|[5-[5-[5-(hydroxymethyl)-2-thiophenyl]-2-furanyl]-2-thiophenyl]methanol	-	CHEMSPIDER	332269	C14H12O3S2	small molecule	-	213261-59-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	RITA binds to p53 and blocks the p53MDM2 interaction	KZENBFUSKMWCJF-UHFFFAOYSA-N
28544	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ma T (2012)	22166212	220337	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
28545	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8594	BI8622	N-[4-(Aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-4-pyrimidinecarboxamide|4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-	-	CHEMSPIDER	75533993	C25H26N6O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IJHAXMJRQQTBPL-UHFFFAOYSA-N
28546	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8617	BI8626	1,3-Benzenedimethanamine, N~1~-[8-[4-(phenylmethyl)-1-piperazinyl]pyrimido[5,4-d]pyrimidin-4-yl]-|N-[3-(Aminomethyl)benzyl]-8-(4-benzyl-1-piperazinyl)pyrimido[5,4-d]pyrimidin-4-amine	-	CHEMSPIDER	75533990	C25H28N8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DZDNGSNKWIORRZ-UHFFFAOYSA-N
28547	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Senisterra G (2018)	29562800	213633	8584	NV03	Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-|N-[3-(Diethylamino)propyl]-2-(5,9-dimethyl-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)acetamide	-	CHEMSPIDER	78316460	C19H27N5O2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	NV03 is an antagonist of the UHRF1 - H3K9me3 interaction	KNZQAVKYBBYDKV-UHFFFAOYSA-N
28548	113168	7320	-	UBE2B	E2-17kDa|HHR6B|HR6B|RAD6B|UBC2	9606	Homo sapiens	inhibitor	target	Sanders MA (2013)	23339190	150227	8622	TZ9	1,3,5-Triazine-2-methanol, 4-amino-6-(phenylamino)-, 4-nitrobenzoate (ester)|(4-Amino-6-anilino-1,3,5-triazin-2-yl)methyl 4-nitrobenzoate	-	CHEMSPIDER	5909766	C17H14N6O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RRRDZFQRNJTKHL-UHFFFAOYSA-N
28549	110811	4734	PIG53	NEDD4	NEDD4-1|RPF1	9606	Homo sapiens	inhibitor	target	Aronchik I (2014)	25009292	166927	8623	Indole-3-carbidol	Indole-3-carbinol|indole-3-methanol|1H-Indol-3-ylmethanol|1H-Indole-3-methanol|3-Indolemethanol|Indole-3-carbidol	-	CHEMSPIDER	3581	C9H9NO	small molecule	-	700-06-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IVYPNXXAYMYVSP-UHFFFAOYSA-N
28550	116243	11059	-	WWP1	AIP5|Tiul1|hSDRP1	9606	Homo sapiens	inhibitor	target	Lee YR (2019)	31097636	223666	8623	Indole-3-carbidol	Indole-3-carbinol|indole-3-methanol|1H-Indol-3-ylmethanol|1H-Indole-3-methanol|3-Indolemethanol|Indole-3-carbidol	-	CHEMSPIDER	3581	C9H9NO	small molecule	-	700-06-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IVYPNXXAYMYVSP-UHFFFAOYSA-N
28551	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	inhibitor	target	Nooka AK (2019)	30694856	223667	8465	CC-92480	4-[4-[[4-[[2-[(3S)-2,6-Dioxopiperidin-3-yl]-1-oxo-3H-isoindol-4-yl]oxymethyl]phenyl]methyl]piperazin-1-yl]-3-fluorobenzonitrile|SCHEMBL20608563|BCP32805|HY-129395|CC92480|CC 92480|CS-0105182|2259648-80-9	-	PUBCHEM	137379043	C32H30FN5O4	small molecule	-	2259648-80-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YTINZZFBHWSAGL-NDEPHWFRSA-N
28552	113169	7321	-	UBE2D1	E2(17)KB1|SFT|UBC4/5|UBCH5|UBCH5A	9606	Homo sapiens	inhibitor	target	Chen H (2017)	28696694	208509	8572	UbcH5c-IN-1	(3aS,9bR)-8-[(2-Bromobenzyl)oxy]-6,9-dimethyl-3-methylene-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one|Naphtho[1,2-b]furan-2(3H)-one, 8-[(2-bromophenyl)methoxy]-3a,4,5,9b-tetrahydro-6,9-dimethyl-3-methylene-, (3aS,9bR)-	-	CHEMSPIDER	71061570	C22H21BrO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IRBNWCSCHCJSLT-LAUBAEHRSA-N
28553	114554	9100	-	USP10	UBPO	9606	Homo sapiens	inhibitor	target	Shao S (2014)	24585095	223668	8614	Spautin-1	MFCD16962292|4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-|6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine|6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine|Spautin-1|C43	-	CHEMSPIDER	25199963	C15H11F2N3	small molecule	-	1262888-28-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AWIVHRPYFSSVOG-UHFFFAOYSA-N
28554	114465	8975	-	USP13	ISOT3|IsoT-3	9606	Homo sapiens	inhibitor	target	Shao S (2014)	24585095	223668	8614	Spautin-1	MFCD16962292|4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-|6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine|6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine|Spautin-1|C43	-	CHEMSPIDER	25199963	C15H11F2N3	small molecule	-	1262888-28-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AWIVHRPYFSSVOG-UHFFFAOYSA-N
28555	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Davies CW (2012)	22617491	132031	8615	Z-VAD(OMe)-FMK	Z-VAD-FMK|L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-|N-[(Benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide|N-[(Benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxo-3-pentanyl]-L-alaninamide	-	CHEMSPIDER	4593742	C22H30FN3O7	small molecule	-	187389-52-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MIFGOLAMNLSLGH-QOKNQOGYSA-N
28556	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Mermerian AH (2007)	17449248	139107	8603	LDN-91946	3-Amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acid|Thieno[2,3-b]pyridine-5-carboxylic acid, 3-amino-2-benzoyl-6,7-dihydro-6-oxo-|LDN-91946	-	CHEMSPIDER	826088	C15H10N2O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OJHMDRZMENMQFP-UHFFFAOYSA-N
28557	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Colombo M (2010)	20186914	223669	8593	DUBs-IN-1	DUBs-IN-1|(9E)-9-[(Benzyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile|9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]-, (9E)-	-	CHEMSPIDER	17225091	C20H11N5O	small molecule	-	924296-18-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GKOWDIBLCDZJHF-NCELDCMTSA-N
28558	114555	9101	-	USP8	HumORF8|SPG59|UBPY	9606	Homo sapiens	inhibitor	target	Colombo M (2010)	20186914	223669	8593	DUBs-IN-1	DUBs-IN-1|(9E)-9-[(Benzyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile|9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]-, (9E)-	-	CHEMSPIDER	17225091	C20H11N5O	small molecule	-	924296-18-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GKOWDIBLCDZJHF-NCELDCMTSA-N
28559	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28560	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28561	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	inhibitor	target	Spradlin JN (2019)	31209351	220371	8586	Nimbolide	methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(furan-3-yl)-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b'c']difuran-6-yl]acetate|2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b'c']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-|GY2370000|Methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(3-furyl)-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[b]furo[2',3',4':4,5]naphtho[2,3-d]furan-6-yl]acetate|nimbolide	-	CHEMSPIDER	10320669	C27H30O7	small molecule	-	25990-37-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JZIQWNPPBKFOPT-LSYMHUITSA-N
28562	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Kategaya L (2017)	29045385	208946	8608	GNE-6640	4-[2-Amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]phenol|Phenol, 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]-	-	CHEMSPIDER	61716303	C20H18N4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZHYXJQQBKROZDX-UHFFFAOYSA-N
28563	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Kategaya L (2017)	29045385	208946	8609	GNE-6776	[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-|6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-3,3'-bipyridine-6-carboxamide	-	CHEMSPIDER	61716302	C20H20N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UCYSSYGGXOFJKK-UHFFFAOYSA-N
28564	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Turnbull AP (2017)	29045389	220338	8607	FT671	4H-Pyrazolo[3,4-d]pyrimidin-4-one, 5-[[1-[(3S)-4,4-difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-|5-({1-[(3S)-4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)butanoyl]-4-hydroxy-4-piperidinyl}methyl)-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one	-	CHEMSPIDER	61709033	C24H23F4N7O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BLSNYSFLZAWBIV-SFHVURJKSA-N
28565	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Ritorto MS (2014)	25159004	223671	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28566	117950	27005	RP11-297K8.3	USP21	USP16|USP23	9606	Homo sapiens	inhibitor	target	Ritorto MS (2014)	25159004	223671	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28567	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Koszela J (2018)	30097011	214402	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28568	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	De Cesare V (2018)	30017913	216529	786	Candesartan	2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid|Candesartan cilexetil|CV-11974|2-Ethoxy-1-(P-(O-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid|Blopress|2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid	auro-candesartan|atacand plus|	DRUGBANK	DB00796	C24H20N6O3	small molecule	C09DB07|C09DA06|C09CA06	139481-59-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Positive hit in high screen assay validated by IC-50 determination.	HTQMVQVXFRQIKW-UHFFFAOYSA-N
28569	120389	55072	-	RNF31	HOIP|ZIBRA	9606	Homo sapiens	inhibitor	target	De Cesare V (2018)	30017913	216529	8091	Bendamustine	Ribomustine	treanda|bendeka	DRUGBANK	DB06769	C16H21Cl2N3O2	small molecule	L01AA09	16506-27-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Positive hit in high screen assay validated by IC-50 determination.	YTKUWDBFDASYHO-UHFFFAOYSA-N
28570	121411	57154	-	SMURF1	-	9606	Homo sapiens	inhibitor	target	Tian M (2019)	30587574	216560	8602	HS-152	4-Chloro-N-({3-[(4-methyl-1-piperazinyl)carbonyl]phenyl}carbamoyl)benzamide|Benzamide, 4-chloro-N-[[[3-[(4-methyl-1-piperazinyl)carbonyl]phenyl]amino]carbonyl]-	-	CHEMSPIDER	88296224	C20H21ClN4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTPUQDJJEKBVQM-UHFFFAOYSA-N
28572	122265	64750	-	SMURF2	-	9606	Homo sapiens	inhibitor	target	Tian M (2019)	30587574	216560	8602	HS-152	4-Chloro-N-({3-[(4-methyl-1-piperazinyl)carbonyl]phenyl}carbamoyl)benzamide|Benzamide, 4-chloro-N-[[[3-[(4-methyl-1-piperazinyl)carbonyl]phenyl]amino]carbonyl]-	-	CHEMSPIDER	88296224	C20H21ClN4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Likely antagonist of the catalytic activity of the HECT domain in SMURF1/2.	OTPUQDJJEKBVQM-UHFFFAOYSA-N
28573	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang Y (2018)	30254335	212629	8589	IU1-248	Benzonitrile, 4-[3-[2-(4-hydroxy-1-piperidinyl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-|4-{3-[(4-Hydroxy-1-piperidinyl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile	-	CHEMSPIDER	88296270	C20H23N3O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WFOUOZGIXDMUJU-UHFFFAOYSA-N
28574	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang Y (2018)	30254335	212629	8587	IU1-206	Ethanone, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxy-1-piperidinyl)-|1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxy-1-piperidinyl)ethanone	-	CHEMSPIDER	30575231	C19H23ClN2O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ORYIJHQLVLSPRM-UHFFFAOYSA-N
28575	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Li H (2018)	30181285	215711	8612	D19	2-[(E)-(1,3-Benzothiazol-2-ylhydrazono)methyl]-1-benzothiophene-3-ol|Benzo[b]thiophene-2-carboxaldehyde, 3-hydroxy-, 2-(2-benzothiazolyl)hydrazone	-	CHEMSPIDER	88294931	C16H11N3OS2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NJUBGVFAHILBQL-RQZCQDPDSA-N
28576	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou B (2018)	28339196	211345	8466	Bivalent ligand 39	BETd-260|Bivalent_ligand_39	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: BETd-260(CRBN:thalidomide --- BDR4:HJB97 (compound 8))	-
28578	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou B (2018)	28339196	211345	8466	Bivalent ligand 39	BETd-260|Bivalent_ligand_39	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: BETd-260(CRBN:thalidomide --- BDR2:HJB97 (compound 8))	-
28580	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou B (2018)	28339196	211345	8466	Bivalent ligand 39	BETd-260|Bivalent_ligand_39	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: BETd-260(CRBN:thalidomide --- BDR3:HJB97 (compound 8))	-
28582	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yang K (2018)	29871848	223608	8529	Bivalent ligand 46	dHDAC6|Bivalent_ligand_46	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: dHDAC6(CRBN:pomalidomide --- HDAC6:pan-HDAC inhibitor AB3)	-
28584	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2018)	29875397	223609	8530	Bivalent ligand 47	P13|Bivalent_ligand_47	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: P13I(CRBN:pomalidomide --- BTK:Ibrutinib)	-
28586	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Testa A (2018)	29949369	213521	8431	Bivalent ligand 65	Bivalent_ligand_65|PROTAC 15a	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 15a (VHL: F-Hyp-containing HIF-1 epitope peptide --- BRD4:JQ1)	-
28588	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zorba A (2018)	30012605	215437	8496	Bivalent ligand 66	PROTAC9|PROTAC10|Bivalent_ligand_66	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 9/10 (CRBN:pomalidomide --- BTK:phenyl-pyrazole derivative analog)	-
28590	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qin C (2018)	30019901	215015	8497	Bivalent ligand 67	QCA570|Bivalent_ligand_67	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: QCA570 (CRBN:thalidomide --- BDR4: QCA276 (BET inhibitor 22))	-
28592	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qin C (2018)	30019901	215015	8497	Bivalent ligand 67	QCA570|Bivalent_ligand_67	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: QCA570 (CRBN:thalidomide --- BDR2: QCA276 (BET inhibitor 22))	-
28594	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qin C (2018)	30019901	215015	8497	Bivalent ligand 67	QCA570|Bivalent_ligand_67	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: QCA570 (CRBN:thalidomide --- BDR3: QCA276 (BET inhibitor 22))	-
28596	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Song Y (2019)	30962579	220135	8498	Bivalent ligand 68	WL40|Bivalent_ligand_68	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	target	Standardized BVL Name: WL40 (CRBN:thalidomide --- RPN13:RA190)	-
28598	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2019)	30672516	223610	8510	Bivalent ligand 71	CRBN-6-5-5-VHL|Bivalent_ligand_71	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: (VHL:VH298 ---CRBN:pomalidomide)	-
28600	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	8512	Bivalent ligand 72	SJFa PROTAC|Bivalent_ligand_72	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	target	SJFalpha PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28602	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	8511	Bivalent ligand 73	SJFd PROTAC|Bivalent_ligand_73	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	target	SJFDelta PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28604	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2019)	30629437	223611	8514	Bivalent ligand 74	ARD-69|Bivalent_ligand_74	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	ARD-69|Standardized BVL Name: (VHL:VHL-e ---AR:enzalutamide)	-
28606	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Krajcovicova S (2019)	30601480	214852	8513	Bivalent ligand 75	8c|Bivalent_ligand_75	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	8c|Standardized BVL Name: (CRBN:thalidomide ---BTK:Despropenoylibrutinib)	-
28608	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Brand M (2019)	30595531	214853	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	BSJ-03-123|Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28610	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bian J (2018)	30196207	214922	8515	Bivalent ligand 77	compund 11c|Bivalent_ligand_77	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	11c|Standardized BVL Name: (CRBN:pomalidomide ---CDK9:wogonin)	-
28612	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Rana S (2019)	30935795	215476	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28614	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	DeMars KM (2019)	30872008	215612	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28616	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Hines J (2019)	30385614	215621	8518	Bivalent ligand 78	A1874|Bivalent_ligand_78	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: A1874(MDM2:idasanutlin --- BRD4:JQ1)	-
28618	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Tinworth CP (2019)	30807093	215660	8517	Bivalent ligand 79	Protac 3|Bivalent_ligand_79	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3 ( CIAP1:piperazine --- BTK:ibrutinib)	-
28620	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li Y (2019)	30525597	223612	8490	Bivalent ligand 82	MD-224|Bivalent_ligand_82	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: MD-224 (CRBN:lenalidomide --- MDM2:MI-1061)	-
28622	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Olson CM (2018)	29251720	214651	8491	Bivalent ligand 83	THAL-SNS-032|Bivalent_ligand_83	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: THAL-SNS-032 (CRBN: thalidomide --- CDK9:SNS-032)	-
28624	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8492	Bivalent ligand 84	Compound 1|Bivalent_ligand_84	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL: compound 15 --- EGFR:lapatinib)	-
28626	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8492	Bivalent ligand 84	Compound 1|Bivalent_ligand_84	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108376	2064	-	ERBB2	CD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1(VHL: compound 15 --- ERBB2:lapitinib)	-
28628	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8468	Bivalent ligand 85	Compound 7|Bivalent_ligand_85	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 7 (VHL: compound 15 --- MET:foretinib)	-
28630	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gechijian LN (2018)	29507391	223613	8494	Bivalent ligand 86	dTRIM24|Bivalent_ligand_86	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	target	Standardized BVL Name: dTRIM24 (VHL:VL-269 --- TRIM24:IACS-7e)	-
28632	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen H (2019)	30901674	215477	8495	Bivalent ligand 87	Compound 2|Bivalent_ligand_87	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: Compound 2 (CRBN:pomalidomide ---BRAF: BRAF ligand)	-
28634	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2018)	30118587	223614	8484	Bivalent ligand 88	Compound 15a|Bivalent_ligand_88	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: Compound 15a (CRBN:pomalidomide ---CRBN:pomalidomide)	-
28636	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- SMARCA2:SMARCABD ligand)	-
28638	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- SMARCA4:SMARCABD ligand)	-
28640	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120490	55193	-	PBRM1	BAF180|PB1	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- PBRM1:SMARCABD ligand)	-
28642	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Popow J (2019)	30739444	223616	8546	Bivalent ligand 90	BI-3663|Bivalent_ligand_90	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: BI-3663 (CRBN:pomalidomide --- PTK2:BI-4464)	-
28644	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang X (2019)	31209349	220534	8545	Bivalent ligand 91	KB02-SLF|Bivalent_ligand_91	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	small molecule|Standardized BVL Name: KB02-SLF (DCAF16:KB02 --- FKBP12:SLF)	-
28646	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang X (2019)	31209349	220534	8544	Bivalent ligand 92	KB02-JQ1|Bivalent_ligand_92	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	small molecule|Standardized BVL Name: KB02-JQ1 (DCAF16:KB02 --- BRD4:JQ1)	-
28648	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	30978004	220718	8543	Bivalent ligand 93	HaloPROTAC-E|Bivalent_ligand_93	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HaloTag7-SGK3)	-
28650	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	30978004	220718	8543	Bivalent ligand 93	HaloPROTAC-E|Bivalent_ligand_93	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111307	5289	-	PIK3C3	VPS34|hVps34	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HaloTag7-PIK3C3)	-
28652	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Z (2019)	31389699	220719	8542	Bivalent ligand 94	PROTAC C3|Bivalent_ligand_94	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110338	4170	-	MCL1	BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT	9606	Homo sapiens	target	Standardized BVL Name: PROTAC C3 (CRBN:pomalidomide ---MCL1:Nap-1)	-
28654	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Z (2019)	31389699	220719	8504	Bivalent ligand 95	PROTAC C5|Bivalent_ligand_95	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	target	Standardized BVL Name: PROTAC C5 (CRBN:pomalidomide ---BCL2:S1-6)	-
28656	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Remillard D (2017)	28418626	207027	8503	Bivalent ligand 96	dBRD9|Bivalent_ligand_96	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: Compound 6 (dBRD9) (CRBN:pomalidomide --- BRD9:GSK-3)	-
28658	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Q (2019)	31539241	220727	8502	Bivalent ligand 97	SIAIS178|Bivalent_ligand_97	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SIAIS178 (VHL:VHL1 --- BCR-ABL:dasatinib)	-
28660	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Posternak G (2020)	32778845	223178	8501	Bivalent ligand 98	P4B|Bivalent_ligand_98	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: P4B(CRBN:pomalidomide --- BRAF:BI 882370)	-
28662	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2019)	31311809	223347	8506	Bivalent ligand 100	GMB-475|Bivalent_ligand_100	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: GMB-475(VHL:VHL1 --- BCR-ABL1:GNF-5)	-
28664	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	30427680	223617	8507	Bivalent ligand 101	FLT-3 PROTAC|Bivalent_ligand_101	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: FLT-3 PROTAC(VHL:VHL1 --- FLT3:quizartinib)	-
28666	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2019)	31730343	223618	8508	Bivalent ligand 102	MS432N|Bivalent_ligand_102	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS432N(VHL:VHL1 --- MAP2K1:PD0325901)	-
28668	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2019)	31730343	223618	8508	Bivalent ligand 102	MS432N|Bivalent_ligand_102	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS432N(VHL:VHL1 --- MAP2K2:PD0325901)	-
28670	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hatcher JM (2018)	29937979	223355	8509	Bivalent ligand 103	JH-XI-10-02|Bivalent_ligand_103	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107458	1024	-	CDK8	K35	9606	Homo sapiens	target	Standardized BVL Name: JH-XI-10-02 (CRBN:pomalidomide --- CDK8:JH-VIII-49)	-
28672	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	31461270	222512	8483	Bivalent ligand 104	SGK3-PROTAC1|Bivalent_ligand_104	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: SGK3-PROTAC1 (VHL:VH032 --- SGK3:308-R)	-
28674	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cromm PM (2018)	30444612	223619	8557	Bivalent ligand 105	PROTAC-3|Bivalent_ligand_105	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-3 (VHL:SAR --- PTK2:defactinib)	-
28676	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chan KH (2018)	28595007	223620	8539	Bivalent ligand 106	MZP-54|MZP-55|Bivalent_ligand_106	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: MZP-55 (VHL: --- BRD4:I-BET726)	-
28678	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chan KH (2018)	28595007	223620	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28680	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chan KH (2018)	28595007	223620	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28682	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Q (2019)	30540295	223621	8505	Bivalent ligand 107	compound-3|Bivalent_ligand_107	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: compound-3 (MDM2:nutlin-3 --- PARP1:niraparib)	-
28684	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Khan S (2019)	31792461	223622	8499	Bivalent ligand 108	DT2216|Bivalent_ligand_108	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: DT2216 (VHL:VHL-L --- BCL2L1:ABT263)	-
28686	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang F (2020)	31813613	223623	8500	Bivalent ligand 109	compound 21|Bivalent_ligand_109	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 21 (CRBN:pomalidomide --- BRD4:compound 5)	-
28688	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yang J (2019)	31560543	223624	8470	Bivalent ligand 110	MG-277|Bivalent_ligand_110	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: MG-277 (CRBN:lenalidomide --- GSPT1:MI-2103)	-
28690	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chi JJ (2019)	31669221	222989	8469	Bivalent ligand 111	CP5V|Bivalent_ligand_111	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107427	991	-	CDC20	CDC20A|bA276H19.3|p55CDC	9606	Homo sapiens	target	Standardized BVL Name: CP5V (VHL:VHL1 --- CDC20:apcin-A)	-
28692	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zoppi V (2019)	30540463	223625	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD9: BRDL1)	-
28694	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zoppi V (2019)	30540463	223625	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118883	29117	-	BRD7	BP75|CELTIX1|NAG4	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD7: BRDL1)	-
28696	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bai L (2019)	31715132	223626	8467	Bivalent ligand 113	SD-36|Bivalent_ligand_113	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	target	Standardized BVL Name: SD-36 (CRBN:lenalidomide --- STAT3:SI-109)	-
28698	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Papatzimas JW (2019)	31117518	220896	8571	Bivalent ligand 114	dMCL1-2|Bivalent_ligand_114	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110338	4170	-	MCL1	BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT	9606	Homo sapiens	target	Standardized BVL Name: dMCL1-2 (CRBN:4-hydroxythalidomide --- MCL1:A-1210477)	-
28700	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kim K (2019)	31873151	223627	8570	Bivalent ligand 115	TD-165|Bivalent_ligand_115	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: TD-165 (VHL:VHL032 --- CRBN:pomalidomide)	-
28702	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen H (2019)	30901674	215477	8569	Bivalent ligand 116	compound 2|Bivalent_ligand_116	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: compound 2 (CRBN:pomalidomide --- B-RAF:B-RAF ligand)	-
28704	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	BasuRay S (2019)	31019090	223628	8568	Bivalent ligand 117	PROTAC3|Bivalent_ligand_117	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	228103	116939	-	Pnpla3	Adpn	10090	Mus musculus	target	Standardized BVL Name: PROTAC3 (VHL:hydroxyproline derivative  --- Pnpla3:HaloTag)	-
28706	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2019)	30858551	223629	8487	Bivalent ligand 118	L18I|Bivalent_ligand_118	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: L18I (CRBN:lenalidomide --- BTK:ibrutinib)	-
28708	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Nunes J (2019)	31312412	223630	8486	Bivalent ligand 119	compound 9|Bivalent_ligand_119	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (VHL:VHL ligand --- IRAK4: PF-06650833)	-
28710	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- PTK2B:TL13-87)	-
28712	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- AURKA:TL13-87)	-
28714	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- PTK2:TL13-87)	-
28716	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- BTK:TL13-87)	-
28718	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- TEC:TL13-87)	-
28720	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- FLT3:TL13-87)	-
28722	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108533	2242	-	FES	FPS	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- FES:TL13-87)	-
28724	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- AAK1:TL13-87)	-
28726	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- ULK1:TL13-87)	-
28728	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK12:TL13-87)	-
28730	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- FER:TL13-87)	-
28732	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- AURKB:TL13-87)	-
28734	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK13:TL13-87)	-
28736	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- MARK2:TL13-87)	-
28738	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- WEE1:TL13-87)	-
28740	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK7:TL13-87)	-
28742	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK17:TL13-87)	-
28744	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- GAK:TL13-87)	-
28746	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK5:TL13-87)	-
28748	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
28750	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
28752	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK9:TL13-87)	-
28754	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
28756	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- PRKAA1:TL13-87)	-
28758	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- LIMK2:TL13-87)	-
28760	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- BLK:TL13-87)	-
28762	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- ITK:TL13-87)	-
28764	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- LCK:TL13-87)	-
28766	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8538	Bivalent ligand 121	TL13-117|Bivalent_ligand_121	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: TL13-117 (CRBN:pomalidomide --- FLT3:AC220)	-
28768	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8535	Bivalent ligand 122	CJH-005-067|Bivalent_ligand_122	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: CJH-005-067 (CRBN:pomalidomide --- BTK:bosutinib)	-
28770	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang HT (2018)	29129717	211728	8536	Bivalent ligand 123	DD-04-015|Bivalent_ligand_123	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DD-04-015 (CRBN:pomalidomide --- BTK:RN486)	-
28772	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qiu X (2019)	31066567	223631	8533	Bivalent ligand 124	SIAIS213110|Bivalent_ligand_124	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: SIAIS213110 (CRBN:lenalidomide --- BRD2:JQ1-acid)	-
28774	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qiu X (2019)	31066567	223631	8533	Bivalent ligand 124	SIAIS213110|Bivalent_ligand_124	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: SIAIS213110 (CRBN:lenalidomide --- BRD3:JQ1-acid)	-
28776	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qiu X (2019)	31066567	223631	8533	Bivalent ligand 124	SIAIS213110|Bivalent_ligand_124	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: SIAIS213110 (CRBN:lenalidomide --- BRD4:JQ1-acid)	-
28778	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lebraud H (2016)	28058282	223632	8534	Bivalent ligand 125	JQ1-CLIPTAC|Bivalent_ligand_125	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: JQ1-CLIPTAC (CRBN:Tz-thalidomide --- BRD4:JQ1)	-
28780	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	target	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK3:Probe 1)	-
28782	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	target	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK1:Probe 1)	-
28784	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2020)	32840532	223633	8532	Bivalent ligand 127	XZ9002|Bivalent_ligand_127	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: XZ9002 (VHL:VH032 --- HDAC3:SR-3558)	-
28786	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	de Wispelaere M (2019)	31371704	223634	8540	Bivalent ligand 128	DGY-08-097|Bivalent_ligand_128	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205534	951475	HCVgp1	HCVgp1	-	11103	Hepatitus C Virus	target	Standardized BVL Name: DGY-08-097(CRBN:tricyclic imide --- NS3/4A:telaprevir; Coronavirus Project; Target UniProt ID P0C045 (NS3/4A))	-
28788	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Degorce SL (2020)	32803978	223635	8541	Bivalent ligand 129	PROTAC 23|Bivalent_ligand_129	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116382	11213	-	IRAK3	ASRT5|IRAKM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 23 (CRBN:W2 --- IRAK3:compound 5)	-
28790	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC1:CI-994)	-
28792	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC2:CI-994)	-
28794	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC3:CI-994)	-
28840	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang M (2020)	32437146	223641	8528	Bivalent ligand 138	SHP2-D26|Bivalent_ligand_138	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: SHP2-D26 (VHL:VHL-1 ligand 6 --- PTPN11:compound 5)	-
28842	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Sun N (2020)	32179332	223642	8527	Bivalent ligand 139	SIAIS117|Bivalent_ligand_139	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: SIAIS117 (VHL:VHL-1 --- ALK:brigatinib)	-
28844	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	McCoull W (2018)	30335946	223643	8558	Bivalent ligand 140	PROTAC 15|Bivalent_ligand_140	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107076	604	-	BCL6	BCL5|BCL6A|LAZ3|ZBTB27|ZNF51	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 15 (CRBN:thalidomide --- BCL6:BCL6 ligand)	-
28846	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Mu X (2020)	31708096	223603	8559	Bivalent ligand 141	HBL-4|Bivalent_ligand_141	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: HBL-4  (CRBN:thalidomide --- BRD4:BI2536)	-
28848	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Mu X (2020)	31708096	223603	8559	Bivalent ligand 141	HBL-4|Bivalent_ligand_141	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: HBL-4  (CRBN:thalidomide --- PLK1:BI2536)	-
28850	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZFP91:pomalidomide)	-
28852	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---ZFP91:lenalidomide)	-
28854	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:thalidomide ---ZFP91:thalidomide)	-
28856	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	124982	92822	-	ZNF276	CENP-Z|CENPZ|ZADT|ZFP276|ZNF477	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZNF276:pomalidomide)	-
28858	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	125464	115950	-	ZNF653	E430039K05Rik|ZIP67	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZNF653:pomalidomide)	-
28860	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	125464	115950	-	ZNF653	E430039K05Rik|ZIP67	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---ZNF653:lenalidomide)	-
28862	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZNF692:pomalidomide)	-
28864	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---ZNF692:lenalidomide)	-
28866	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:thalidomide ---ZNF692:thalidomide)	-
28868	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	127447	152485	-	ZNF827	-	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZNF827:pomalidomide)	-
28870	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	127447	152485	-	ZNF827	-	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---ZNF827:lenalidomide)	-
28872	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	127447	152485	-	ZNF827	-	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:thalidomide ---ZNF827:thalidomide)	-
28874	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---IKZF3:pomalidomide)	-
28876	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---IKZF3:lenalidomide)	-
28878	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---IKZF1:pomalidomide)	-
28880	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---IKZF1:lenalidomide)	-
28882	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121845	58525	-	WIZ	ZNF803	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---WIZ:lenalidomide)	-
28884	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sievers QL (2018)	30385546	212829	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121845	58525	-	WIZ	ZNF803	9606	Homo sapiens	target	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:CC-122 ---WIZ:CC-122)	-
28886	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Crew AP (2018)	28692295	217494	8488	Bivalent ligand 80	PROTAC 3i|Bivalent_ligand_80	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3i (VHL:VHL ligand 2 ---TBK1:ligand 1b)	-
28888	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li Z (2020)	31735695	223644	8489	Bivalent ligand 81	Bivalent_ligand_81	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:pomalidomide ---Wee1:ZNL-02-096)	-
28890	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Shan Y (2020)	32750566	223645	8563	Bivalent ligand 145	PROTAC 5|Bivalent_ligand_145	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5(VHL:VH032 ---KDR:ABT-869)	-
28892	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	degradation	recruited e3 ligase	Li L (2020)	32713946	223646	8564	Bivalent ligand 146	DP1|Bivalent_ligand_146	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: DP1(DCAF15:E7820 --- BRD4:JQ1)	-
28894	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Y (2020)	32717479	223647	8565	Bivalent ligand 147	Compound 11|Bivalent_ligand_147	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118953	29904	-	EEF2K	HSU93850|eEF-2K	9606	Homo sapiens	target	Standardized BVL Name: Compound 11l (CRBN:thalidomide --- EEF2K:A484954)	-
28896	111105	5071	KB-152G3.1	PARK2	AR-JP|LPRS2|PDJ|PRKN	9606	Homo sapiens	degradation	recruited e3 ligase	Schiedel M (2020)	32672888	223648	8566	Bivalent ligand 148	chloroalkylated SirReal 11|Bivalent_ligand_148	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: chloroalkylated SirReal 11 (HaloTag-PRKN--- SIRT2:SirReal3)	-
28898	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- ULK1-GFP:GFP-HaloTag)	-
28900	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	123547	81610	-	FAM83D	C20orf129|CHICA|dJ616B8.3	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- FAM83D-GFP:GFP-HaloTag)	-
28902	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- SGK3-GFP:GFP-HaloTag)	-
28904	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HRAS:RASabHaloTag)	-
28906	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- KRAS:RASabHaloTag)	-
28908	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Barrios AM (2020)	32615037	223650	8550	Bivalent ligand 150	compound 26|Bivalent_ligand_150	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: compound 26 (VHL:VHL ligand --- PTPN11:SHP099)	-
28910	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cheng J (2020)	32603594	223651	8549	Bivalent ligand 151	compound 17f|Bivalent_ligand_151	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111173	5147	-	PDE6D	JBTS22|PDED	9606	Homo sapiens	target	Standardized BVL Name: compound 17f (CRBN:pomalidomide --- PDE6D:deltazinone)	-
28912	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK14:PH-797804)	-
28914	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111586	5600	-	MAPK11	P38B|P38BETA2|PRKM11|SAPK2|SAPK2B|p38-2|p38Beta	9606	Homo sapiens	target	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK11:PH-797804)	-
28916	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	degradation	recruited e3 ligase	Tong B (2020)	32568522	223653	8547	Bivalent ligand 153	BT1|Bivalent_ligand_153	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: BT1 (RNF114:nimbolide --- BCR-ABL:dasatinib)	-
28918	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liao H (2020)	32550000	223654	8554	Bivalent ligand 154	xStAx-VHLL|Bivalent_ligand_154	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	target	Standardized BVL Name: xStAx-VHLL (VHL:VHL ligand --- CTNNB1:xStAx)	-
28920	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2020)	32519703	223655	8553	Bivalent ligand 155	GMB-805|Bivalent_ligand_155	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: GMB-805 (VHL:VHL1 --- BCR-ABL:ABL001)	-
28922	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Field SD (2020)	32501609	223656	8552	Bivalent ligand 156	Degrader 3|Bivalent_ligand_156	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116444	11313	RP5-886K2.5	LYPLA2	APT-2|DJ886K2.4	9606	Homo sapiens	target	Standardized BVL Name: Degrader 3 (CRBN:pomalidomide --- LYPLA2:fluorophosphonate reactive group)	-
28924	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gao H (2020)	32451721	223657	8551	Bivalent ligand 157	FAK-PROTAC|Bivalent_ligand_157	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199587	14083	-	Ptk2	FAK|FRNK|Fadk|mKIAA4203|p125FAK	10090	Mus musculus	target	Standardized BVL Name: FC-11 (CRBN:pomalidomide --- Ptk2:PF562271)	-
28928	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jaime-Figueroa S (2020)	31879210	223659	8555	Bivalent ligand 159	SJF620|Bivalent_ligand_159	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: SJF620 (CRBN:lenalidomide --- BTK:Ibrutinib)	-
28930	111974	6047	RES4-26	RNF4	SLX5|SNURF	9606	Homo sapiens	degradation	recruited e3 ligase	Ward CC (2019)	31059647	220118	8477	Bivalent ligand 160	CCW 28-3|Bivalent_ligand_160	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CCW 28-3 (RNF4:CCW 16 --- BRD4:JQ1)	-
28932	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	degradation	recruited e3 ligase	Spradlin JN (2019)	31209351	220371	8478	Bivalent ligand 161	XH2|Bivalent_ligand_161	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: XH2 (RNF114:nimbolide --- BRD4:JQ1)	-
28934	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Silva MC (2019)	30907729	219824	8475	Bivalent ligand 162	QC-01x96175|Bivalent_ligand_162	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: QC-01175 (CRBN:pomalidomide --- MAPT:T807)	-
28936	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK4:palbociclib)	-
28938	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK6:palbociclib)	-
28940	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK4:ribociclib)	-
28942	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK6:ribociclib)	-
28944	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK4:abemaciclib)	-
28946	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK6:abemaciclib)	-
28948	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK9:abemaciclib)	-
28950	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8479	Bivalent ligand 166	BSJ-01-187|Bivalent_ligand_166	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ01187 (CRBN:thalidomide --- CDK4:ribociclib)	-
28952	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8480	Bivalent ligand 167	YKL-06-102|Bivalent_ligand_167	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: YKL06102 (CRBN:thalidomide --- CDK6:palbociclib)	-
28954	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8479	Bivalent ligand 166	BSJ-01-187|Bivalent_ligand_166	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: BSJ01187 (CRBN:thalidomide --- IKZF1:ribociclib)	-
28956	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8480	Bivalent ligand 167	YKL-06-102|Bivalent_ligand_167	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: YKL06102 (CRBN:thalidomide --- IZKF1:palbociclib)	-
28958	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- IZKF1:palbociclib)	-
28960	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8479	Bivalent ligand 166	BSJ-01-187|Bivalent_ligand_166	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: BSJ01187 (CRBN:thalidomide --- IKZF3:ribociclib)	-
28962	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8480	Bivalent ligand 167	YKL-06-102|Bivalent_ligand_167	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: YKL06102 (CRBN:thalidomide --- IZKF3:palbociclib)	-
28964	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: BSJ02162  (CRBN:thalidomide --- IZKF3:palbociclib)	-
28966	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK4:palbociclib)	-
28968	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK6:palbociclib)	-
28970	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8474	Bivalent ligand 169	BSJ-04-132|Bivalent_ligand_169	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ04132 (CRBN:thalidomide --- CDK4:ribociclib)	-
28972	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2019)	30802347	223660	8472	Bivalent ligand 170	BSJ-03-123|Bivalent_ligand_170	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ03123 (CRBN:thalidomide --- CDK6:palbociclib)	-
28974	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	target	Standardized BVL Name: peptide 5 (BIRC2:MV1 --- NOTCH1:CSL)	-
28976	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	target	Standardized BVL Name: peptide 5 (BIRC3:MV1 --- NOTCH1:CSL)	-
28978	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	target	Standardized BVL Name: peptide 5 (XIAP1:MV1 --- NOTCH1:CSL)	-
29118	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9188	(1R,2As,4S,7S,10S,13S,19S,22S,25S,28S,31R,36R,39S,45R,48S,51S,54S,57R,60S,63S,66S,69S,72S,75S,78S,81S,84S,87S,90R,93S,96S,99S)-10,51,75,87-tetrakis(4-aminobutyl)-31-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-93-(3-amino-3-oxopropyl)-60,96-dibenzyl-19,28-bis[(2S)-butan-2-yl]-4,54,69-tris(3-carbamimidamidopropyl)-25-(carboxymethyl)-2a,22,39,48-tetrakis[(1R)-1-hydroxyethyl]-7,63,81-tris(hydroxymethyl)-72-[(4-hydroxyphenyl)methyl]-84-(1H-imidazol-5-ylmethyl)-99-methyl-66-(2-methylpropyl)-78-(2-methylsulfanylethyl)-1a,3,4a,6,9,12,18,21,24,27,30,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-dotriacontaoxo-6a,7a,10a,11a,33,34-hexathia-a,2,3a,5,8,11,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-dotriacontazatetracyclo[55.47.4.445,90.013,17]dodecahectane-36-carboxylic acid	BDBM50115771	-	PUBCHEM	122187344	C169H274N54O48S7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GVRGDWHECZKHIP-CINJXCJGSA-N
29119	109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9189	(1R,2As,4S,7S,10S,13S,19S,22S,25S,28S,31R,36R,39S,45R,48S,51S,54S,57R,60S,63S,66S,69S,72S,75S,78S,81S,84S,87S,90R,93S,96S,99S)-10,51,75,87-tetrakis(4-aminobutyl)-31-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-93-(3-amino-3-oxopropyl)-60,96-dibenzyl-19,28-bis[(2S)-butan-2-yl]-78-butyl-4,54,69-tris(3-carbamimidamidopropyl)-25-(carboxymethyl)-2a,22,39,48-tetrakis[(1R)-1-hydroxyethyl]-7,63,81-tris(hydroxymethyl)-72-[(4-hydroxyphenyl)methyl]-84-(1H-imidazol-5-ylmethyl)-99-methyl-66-(2-methylpropyl)-1a,3,4a,6,9,12,18,21,24,27,30,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-dotriacontaoxo-6a,7a,10a,11a,33,34-hexathia-a,2,3a,5,8,11,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-dotriacontazatetracyclo[55.47.4.445,90.013,17]dodecahectane-36-carboxylic acid	BDBM50115767	-	PUBCHEM	122187340	C170H276N54O48S6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCAVQHJGLXITPN-HMILKZLESA-N
29120	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9190	CID 122187346	BDBM50115773	-	PUBCHEM	122187346	C184H295N56O56PS7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IUXTUGDAYSHYDJ-UYSYBMGHSA-N
29121	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9191	(1R,2As,4S,7S,10S,13S,19S,22S,25S,28S,31R,36R,39S,45R,48S,51S,54S,57R,60S,63S,66S,69S,72S,75S,78S,81S,84S,87S,90R,93S,96S,99S)-10,51,87-tris(4-aminobutyl)-31-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-75-(aminomethyl)-93-(3-amino-3-oxopropyl)-60,96-dibenzyl-19,28-bis[(2S)-butan-2-yl]-4,54,69-tris(3-carbamimidamidopropyl)-25-(carboxymethyl)-2a,22,39,48-tetrakis[(1R)-1-hydroxyethyl]-7,63,81-tris(hydroxymethyl)-72-[(4-hydroxyphenyl)methyl]-84-(1H-imidazol-5-ylmethyl)-99-methyl-66-(2-methylpropyl)-78-(2-methylsulfanylethyl)-1a,3,4a,6,9,12,18,21,24,27,30,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-dotriacontaoxo-6a,7a,10a,11a,33,34-hexathia-a,2,3a,5,8,11,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-dotriacontazatetracyclo[55.47.4.445,90.013,17]dodecahectane-36-carboxylic acid	BDBM50115772	-	PUBCHEM	122187345	C166H268N54O48S7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PFWOJTLVNOZSGQ-RIMJLNMDSA-N
29122	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9188	(1R,2As,4S,7S,10S,13S,19S,22S,25S,28S,31R,36R,39S,45R,48S,51S,54S,57R,60S,63S,66S,69S,72S,75S,78S,81S,84S,87S,90R,93S,96S,99S)-10,51,75,87-tetrakis(4-aminobutyl)-31-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-93-(3-amino-3-oxopropyl)-60,96-dibenzyl-19,28-bis[(2S)-butan-2-yl]-4,54,69-tris(3-carbamimidamidopropyl)-25-(carboxymethyl)-2a,22,39,48-tetrakis[(1R)-1-hydroxyethyl]-7,63,81-tris(hydroxymethyl)-72-[(4-hydroxyphenyl)methyl]-84-(1H-imidazol-5-ylmethyl)-99-methyl-66-(2-methylpropyl)-78-(2-methylsulfanylethyl)-1a,3,4a,6,9,12,18,21,24,27,30,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-dotriacontaoxo-6a,7a,10a,11a,33,34-hexathia-a,2,3a,5,8,11,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-dotriacontazatetracyclo[55.47.4.445,90.013,17]dodecahectane-36-carboxylic acid	BDBM50115771	-	PUBCHEM	122187344	C169H274N54O48S7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GVRGDWHECZKHIP-CINJXCJGSA-N
29123	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Murray JK (2015)	26288216	224769	9189	(1R,2As,4S,7S,10S,13S,19S,22S,25S,28S,31R,36R,39S,45R,48S,51S,54S,57R,60S,63S,66S,69S,72S,75S,78S,81S,84S,87S,90R,93S,96S,99S)-10,51,75,87-tetrakis(4-aminobutyl)-31-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-93-(3-amino-3-oxopropyl)-60,96-dibenzyl-19,28-bis[(2S)-butan-2-yl]-78-butyl-4,54,69-tris(3-carbamimidamidopropyl)-25-(carboxymethyl)-2a,22,39,48-tetrakis[(1R)-1-hydroxyethyl]-7,63,81-tris(hydroxymethyl)-72-[(4-hydroxyphenyl)methyl]-84-(1H-imidazol-5-ylmethyl)-99-methyl-66-(2-methylpropyl)-1a,3,4a,6,9,12,18,21,24,27,30,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-dotriacontaoxo-6a,7a,10a,11a,33,34-hexathia-a,2,3a,5,8,11,17,20,23,26,29,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97-dotriacontazatetracyclo[55.47.4.445,90.013,17]dodecahectane-36-carboxylic acid	BDBM50115767	-	PUBCHEM	122187340	C170H276N54O48S6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCAVQHJGLXITPN-HMILKZLESA-N
29124	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Zhang Y (2015)	26191364	212887	9192	(8S,11S,14S,17S,28S,31S,34S,37R)-37-(Cyclopropylsulfonylamino)-10,30-bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,34-bis(naphthalen-2-ylmethyl)-12,15,32,35-tetraoxo-2,23-dioxa-5,6,7,10,13,16,30,33,36-nonazahexacyclo[37.2.2.219,22.14,7.18,11.128,31]octatetraconta-1(42),4(48),5,19,21,39(43),40,45-octaene-17-carboxylic acid	BDBM50112346	-	PUBCHEM	122187534	C83H106N14O14S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MLQVQPMTZJBGEY-VGEDNRJQSA-N
29125	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Zhang Y (2015)	26191364	212887	9192	(8S,11S,14S,17S,28S,31S,34S,37R)-37-(Cyclopropylsulfonylamino)-10,30-bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,34-bis(naphthalen-2-ylmethyl)-12,15,32,35-tetraoxo-2,23-dioxa-5,6,7,10,13,16,30,33,36-nonazahexacyclo[37.2.2.219,22.14,7.18,11.128,31]octatetraconta-1(42),4(48),5,19,21,39(43),40,45-octaene-17-carboxylic acid	BDBM50112346	-	PUBCHEM	122187534	C83H106N14O14S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MLQVQPMTZJBGEY-VGEDNRJQSA-N
29126	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Holzer P (2015)	26181851	224770	9193	Nvp-cgm097	ZINC253387855|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-[METHYL-[[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-7-PROPAN-2-YLOXY-1,4-DIHYDROISOQUINOLIN-3-ONE|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-[METHYL[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)-TRANS-CYCLOHEXYLMETHYL]AMINO]PHENYL)-1,4-DIHYDRO-2H-ISOQUINOLIN-3-ONE|4UF6MSL0ZH|NVP-CGM-097|KS-00000TSY|CCG-270337|US9051279, 106|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-(METHYL{[TRANS-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL}AMINO)PHENYL]-7-(PROPAN-2-YLOXY)-1,4-DIHYDROISOQUINOLIN-3(2H)-ONE|EX-A1059|CS-3138|HY-15954|NVP-CGM097 (CGM-097)|NVP-CGM097|Q27454942|NCGC00390552-01|W5747|4T4|NVP CGM097|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-{4-[METHYL({[(1R,4R)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL})AMINO]PHENYL}-7-(PROPAN-2-YLOXY)-1,2,3,4-TETRAHYDROISOQUINOLIN-3-ONE|C38H47CLN4O4|1313363-54-0|(1S)-1-(4-CHLOROPHENYL)-1,4-DIHYDRO-6-METHOXY-7-(1-METHYLETHOXY)-2-[4-[METHYL[[TRANS-4-(4-METHYL-3-OXO-1-PIPERAZINYL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-3(2H)-ISOQUINOLINONE|CGM-097|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-(METHYL(((1R,4S)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL)METHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE|UNII-4UF6MSL0ZH|A16326|AS-75288|S7875|CGM097|J3.509.326E|CGM 097|BCP18308|AKOS030526402|BDBM162123	-	PUBCHEM	53240420	C38H47ClN4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CLRSLRWKONPSRQ-CPOWQTMSSA-N
29127	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9194	N-[6-[3-(5-Aminopentoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	NCCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C=2N=CN(C=2)C)C=C(C=1)OCCC|BDBM50150822	-	PUBCHEM	118896579	C27H36N6O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KYGTZHDLDHFQHW-UHFFFAOYSA-N
29128	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9195	N-[6-[3-(4-Aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	NCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C=2N=CN(C=2)C)C=C(C=1)OCCC|BDBM50150821	-	PUBCHEM	118896387	C26H34N6O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QVUCXHDGQWWKCE-UHFFFAOYSA-N
29129	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9196	N-[6-[3-(4-Aminobutoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	NCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C2=CC(=C(C=C2)OC)OC)C=C(C=1)OCCC|BDBM50150820	-	PUBCHEM	118896486	C30H38N4O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QPZLILYRGDXDKP-UHFFFAOYSA-N
29130	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9197	N-[6-[3-(3-Aminopropoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	NCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C2=CC(=C(C=C2)OC)OC)C=C(C=1)OCCC|BDBM50150819	-	PUBCHEM	118896529	C29H36N4O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FUPXEMIBURHODB-UHFFFAOYSA-N
29131	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9198	N-[6-[3-[4-(Dimethylamino)butoxy]-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	1800477-30-8|Q27454585|N-[6-[3-[4-(DIMETHYLAMINO)BUTOXY]-5-PROPOXYPHENOXY]-1,3-DIMETHYL-2-OXOBENZIMIDAZOL-5-YL]-3,4-DIMETHOXYBENZENESULFONAMIDE|IACS-9571|4C1|CS-7640|HY-102000|J3.601.427J|N-(6-{3-[4-(DIMETHYLAMINO)BUTOXY]-5-PROPOXYPHENOXY}-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-5-YL)-3,4-DIMETHOXYBENZENESULFONAMIDE|BDBM50150818	-	PUBCHEM	91808039	C32H42N4O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HYQBRUSSCIAOOD-UHFFFAOYSA-N
29132	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9199	N-[1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	CN1C(N(C2=C1C=C(C(=C2)NS(=O)(=O)C1=CC(=C(C=C1)OC)OC)OC1=CC(=CC=C1)OCCC)C)=O|BDBM50150812	-	PUBCHEM	118896778	C26H29N3O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DYNNLYLIKZTWRT-UHFFFAOYSA-N
29133	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9200	N-[1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)benzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	CN1C(N(C2=C1C=C(C(=C2)NS(=O)(=O)C=1N=C(N(C=1)C)C)OC1=CC(=CC=C1)OCCC)C)=O|BDBM50150811	-	PUBCHEM	118896759	C23H27N5O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LSCCJMMALWILLE-UHFFFAOYSA-N
29134	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9201	N-[1,3-Dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxobenzimidazol-5-yl]-1,2-dimethylimidazole-4-sulfonamide	N-{1,3-DIMETHYL-6-[3-(2-METHYLPROPOXY)PHENOXY]-2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL}-1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONAMIDE|N-[1,3-DIMETHYL-6-[3-(2-METHYLPROPOXY)PHENOXY]-2-OXOBENZIMIDAZOL-5-YL]-1,2-DIMETHYLIMIDAZOLE-4-SULFONAMIDE|Q27454574|N-{1,3-DIMETHYL-6-[3-(2-METHYLPROPOXY)PHENOXY]-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-5-YL}-1,2-DIMETHYL-1H-IMIDAZOLE-4-SULFONAMIDE|4BK|BDBM50150808	-	PUBCHEM	91808037	C24H29N5O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QYVGOEVQCUQELI-UHFFFAOYSA-N
29135	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9202	N-[1,3-Dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]benzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	CN1C(N(C2=C1C=C(C(=C2)NS(=O)(=O)C=1N=CN(C=1)C)OC1=CC(=CC=C1)OCC1COCC1)C)=O|BDBM50150761	-	PUBCHEM	118896487	C24H27N5O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XUYARXQUNNANMN-UHFFFAOYSA-N
29136	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9203	N-[6-[3-(6-Aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	N-(6-(3-((6-AMINOHEXYL)OXY)-5-PROPOXYPHENOXY)-1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE|NCCCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C=2N=CN(C=2)C)C=C(C=1)OCCC|BDBM50150758	-	PUBCHEM	118896376	C28H38N6O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZKGVLQRSNIMICL-UHFFFAOYSA-N
29137	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9204	N-[6-[3-(6-Hydroxyhexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-1-methylimidazole-4-sulfonamide	OCCCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C=2N=CN(C=2)C)C=C(C=1)OCCC|BDBM50150757	-	PUBCHEM	118896640	C28H37N5O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KVQHINMFWSWVOJ-UHFFFAOYSA-N
29138	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	unknown	target	Palmer WS (2016)	26061247	224771	9205	N-[6-[3-(6-Aminohexoxy)-5-propoxyphenoxy]-1,3-dimethyl-2-oxobenzimidazol-5-yl]-3,4-dimethoxybenzenesulfonamide	NCCCCCCOC=1C=C(OC=2C(=CC3=C(N(C(N3C)=O)C)C=2)NS(=O)(=O)C2=CC(=C(C=C2)OC)OC)C=C(C=1)OCCC|BDBM50150756	-	PUBCHEM	118896472	C32H42N4O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CKWMQEHOKHQQEY-UHFFFAOYSA-N
29139	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9206	[(2S,4R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-4-fluoropyrrolidin-2-yl]-[(6R)-6-ethyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	BDBM50069632	-	PUBCHEM	46840822	C34H38Cl2F2N6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QUYOIFDRHGZSFZ-YABFKZQLSA-N
29140	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9207	[(2S,4R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-4-fluoropyrrolidin-2-yl]-[(6S)-6-methyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	[(2S,4R)-1-[(5R,6S)-5-(4-CHLORO-3-FLUOROPHENYL)-6-(6-CHLOROPYRIDIN-3-YL)-6-METHYL-3-PROPAN-2-YL-5H-IMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBONYL]-4-FLUOROPYRROLIDIN-2-YL]-[(6S)-6-METHYL-4,7-DIAZASPIRO[2.5]OCTAN-7-YL]METHANONE|(6S)-7-[(4R)-1-{[(5R,6S)-5-(4-CHLORO-3-FLUOROPHENYL)-6-(6-CHLOROPYRIDIN-3-YL)-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOL-2-YL]CARBONYL}-4-FLUORO-L-PROLYL]-6-METHYL-4,7-DIAZASPIRO[2.5]OCTANE|BDBM50069631	-	PUBCHEM	46840819	C33H36Cl2F2N6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OKIDBNYMCUVSLU-QSSUNTQZSA-N
29141	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9208	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-[(6S)-6-methyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	BDBM50069630	-	PUBCHEM	87252803	C34H39Cl2FN6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KUZMUIBQNCSWPP-BYJYTBDMSA-N
29142	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9209	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069629	-	PUBCHEM	87252745	C33H37Cl2FN6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FZPRQVYQBJKIQG-KERGWKIMSA-N
29143	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9210	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069628	-	PUBCHEM	67058381	C34H38Cl2FN5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LIFXVTDIRXSOPW-ZNGXGWPMSA-N
29144	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9211	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069627	-	PUBCHEM	44596000	C34H39Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XLBQSMBISPUIMT-MAMXRPNDSA-N
29145	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9212	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4-methyl-4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069626	-	PUBCHEM	67058380	C35H41Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZCAFJDRQRAWKAO-GRZVAKJNSA-N
29146	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9213	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-[(3R)-3,4-dimethylpiperazin-1-yl]methanone	(5R,6S)-5,6-BIS(4-CHLOROPHENYL)-2-[((2S,5R)-2-{[(3R)-3,4-DIMETHYLPIPERAZIN-1-YL]CARBONYL}-5-METHYLPYRROLIDIN-1-YL)CARBONYL]-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE|[(2S,5R)-1-[(5R,6S)-5,6-BIS(4-CHLOROPHENYL)-6-METHYL-3-PROPAN-2-YL-5H-IMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBONYL]-5-METHYLPYRROLIDIN-2-YL]-[(3R)-3,4-DIMETHYLPIPERAZIN-1-YL]METHANONE|BDBM50069625	-	PUBCHEM	58007373	C34H41Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZEYRMSIQYBSOGW-KBVCYFDGSA-N
29147	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Lawrence HR (2015)	25699576	224773	9214	BDBM98282	-	-	CHEMBL	CHEMBL2325940	C24H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PILAMBNAJPBLFA-RWXRFDSASA-N
29148	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Lawrence HR (2015)	25699576	224773	9215	5-Chloro-2-N-[4-(4-methylpiperazin-1-yl)phenyl]-4-N-[[(2S)-oxolan-2-yl]methyl]pyrimidine-2,4-diamine	BDBM50084465	-	PUBCHEM	117859438	C20H27ClN6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MMJSYUQCKWEFRW-KRWDZBQOSA-N
29149	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Lawrence HR (2015)	25699576	224773	9216	5-Chloro-2-N-[4-(4-methylpiperazin-1-yl)phenyl]-4-N-[[(2R)-oxolan-2-yl]methyl]pyrimidine-2,4-diamine	J3.522.184K|N-[[(R)-TETRAHYDROFURAN-2-YL]METHYL]-5-CHLORO-2-[[4-(4-METHYL-1-PIPERAZINYL)PHENYL]AMINO]PYRIMIDINE-4-AMINE|5-CHLORO-2-N-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-4-N-[[(2R)-OXOLAN-2-YL]METHYL]PYRIMIDINE-2,4-DIAMINE|BDBM50084464	-	PUBCHEM	90479825	C20H27ClN6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MMJSYUQCKWEFRW-QGZVFWFLSA-N
29150	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Lawrence HR (2015)	25699576	224773	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
29151	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Lawrence HR (2015)	25699576	224773	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
29152	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9217	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078360	-	PUBCHEM	71582189	C80H96N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RPYLESOPIPCLOC-IJLYYPGQSA-N
29153	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9218	(2S,5S,8S,11S,17S,20S,23S,26S)-4,19-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-8,23-bis(naphthalen-2-ylmethyl)-6,9,21,24-tetraoxo-1,4,7,10,14,15,16,19,22,25,29,30-dodecazapentacyclo[26.2.1.12,5.113,16.117,20]tetratriaconta-13(33),14,28(31),29-tetraene-11,26-dicarboxylic acid	BDBM50078359	-	PUBCHEM	71582339	C64H80N16O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCYVAJKIAWNFPS-WBVBMDTLSA-N
29154	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9219	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078354	-	PUBCHEM	89569624	C84H100N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HZGOIKMHTUCXAI-KWEJKZBISA-N
29155	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9217	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078360	-	PUBCHEM	71582189	C80H96N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RPYLESOPIPCLOC-IJLYYPGQSA-N
29156	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9218	(2S,5S,8S,11S,17S,20S,23S,26S)-4,19-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-8,23-bis(naphthalen-2-ylmethyl)-6,9,21,24-tetraoxo-1,4,7,10,14,15,16,19,22,25,29,30-dodecazapentacyclo[26.2.1.12,5.113,16.117,20]tetratriaconta-13(33),14,28(31),29-tetraene-11,26-dicarboxylic acid	BDBM50078359	-	PUBCHEM	71582339	C64H80N16O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCYVAJKIAWNFPS-WBVBMDTLSA-N
29157	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9220	(10S,13S,16S,19S,33S,36S,39S,42S)-16,39-Dibenzyl-12,35-bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3,14,17,26,37,40-hexaoxo-2,7,8,9,12,15,18,25,30,31,32,35,38,41-tetradecazaheptacyclo[42.2.2.221,24.16,9.110,13.129,32.133,36]tetrapentaconta-1(47),6(54),7,21,23,29(50),30,44(48),45,51-decaene-19,42-dicarboxylic acid	BDBM50078358	-	PUBCHEM	71581702	C74H94N18O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LKZUGDULMRPQJR-PZOHCTHGSA-N
29158	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9221	(8S,11S,14S,17S,29S,32S,35S,38S)-14,35-Dibenzyl-10,31-bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078357	-	PUBCHEM	71581703	C70H88N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VLPFNQKFYWKXGS-JCDMWVPISA-N
29159	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9222	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-1-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078356	-	PUBCHEM	118732795	C78H92N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BUUIRUGUZNCDSQ-KCUAZDICSA-N
29160	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9223	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078355	-	PUBCHEM	71581838	C78H92N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSGZGDDJOKLCEY-PFFMIVSTSA-N
29161	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9219	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078354	-	PUBCHEM	89569624	C84H100N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HZGOIKMHTUCXAI-KWEJKZBISA-N
29163	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9224	CID 70677271	MI-1061|4-((3'R,4'S,5'R)-6''-CHLORO-4'-(3-CHLORO-2-FLUOROPHENYL)-2''-OXODISPIRO[CYCLOHEXANE-1,2'-PYRROLIDINE-3',3''-INDOLINE]-5'-CARBOXAMIDO)BENZOIC ACID|HY-125858|CS-0102051|1410737-34-6|BDBM50041086	-	PUBCHEM	70677271	C30H26Cl2FN3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BIDSEXPFIMKDMF-LOLKONATSA-N
29164	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9225	BDBM50041085	-	-	CHEMBL	CHEMBL3355429	C28H30Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CQRICESTNDBKIY-KUGUZAOFSA-N
29165	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9226	CID 118720818	BDBM50041081	-	PUBCHEM	118720818	C27H30Cl2FN3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UKYBEEZQFSEMPW-LPJWUPNOSA-N
29166	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9227	BDBM50041075	-	-	CHEMBL	CHEMBL3355417	C30H34Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVWMOYGSAUBCGS-WPUIHRAISA-N
29167	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9228	BDBM50041074	-	-	CHEMBL	CHEMBL3355416	C29H32Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QQOSBFYZJBKRMS-UAKSBLKBSA-N
29168	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9229	BDBM50041073	-	-	CHEMBL	CHEMBL3355415	C28H30Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQXQIUHXDOQUSV-XLKFOPSHSA-N
29169	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9230	BDBM50041031	-	-	CHEMBL	CHEMBL3355411	C28H32Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IRTYMVBGDAJRNN-XLKFOPSHSA-N
29170	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9231	CID 71023165	US8629141, 15|BDBM112748	-	PUBCHEM	71023165	C29H33Cl2FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZULOPCMLZWFEKU-ZLZBJJAKSA-N
29171	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Zhao Y (2015)	25396320	224776	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29172	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Rew Y (2014)	25384157	224777	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29173	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Rew Y (2014)	25384157	224777	9233	4-[[2-[(3R,5R,6S)-1-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetyl]amino]-2-methoxybenzoic acid	3UD|4WT2|US8952036, EX. 3|4-(2-((3R,5R,6S)-1-((S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL)-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETAMIDO)-2-METHOXYBENZOIC ACID|4-[[2-[(3R,5R,6S)-1-[(1S)-2-TERT-BUTYLSULFONYL-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETYL]AMINO]-2-METHOXYBENZOIC ACID|4-({[(3R,5R,6S)-1-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETYL}AMINO)-2-METHOXYBENZOIC ACID|Q27454148|BDBM144638	-	PUBCHEM	77108133	C37H41Cl2FN2O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGOICCMBEDDFCI-NXQGQTBASA-N
29174	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9234	4-N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030280	-	PUBCHEM	73506219	C63H82N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAKVXIUNQHYAPX-UPKUDDMJSA-N
29175	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9235	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methoxy]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030278	-	PUBCHEM	90089727	C63H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PXWQVOUQYPMEME-NMZKVUILSA-N
29176	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9236	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethynyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030275	-	PUBCHEM	90089572	C64H81N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MZOKCLGAIIRHDG-KHFWCYFCSA-N
29177	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9237	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030273	-	PUBCHEM	90089737	C64H85N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MRQUIOMXZIGPPW-KHFWCYFCSA-N
29178	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9238	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-benzothiazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030272	-	PUBCHEM	118497975	C64H81N11O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SYZOGRWMVSXFBX-OVCCXHLHSA-N
29179	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9239	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-oxazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030270	-	PUBCHEM	73507318	C60H79N11O9	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VYZMHQWZWYAOIA-QLYDQGARSA-N
29180	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9240	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030269	-	PUBCHEM	118323269	C63H83N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LDVMHSURAWAEBW-YUTDAYPPSA-N
29181	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9241	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-1-(2-fluorophenyl)ethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030268	-	PUBCHEM	73603510	C61H80FN9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SUVGZSPIXFUCLS-NQFXVQPCSA-N
29182	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9242	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030266	-	PUBCHEM	73603641	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-DFNGJWONSA-N
29183	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9243	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030265	-	PUBCHEM	118715865	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-UICOXBBFSA-N
29184	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9234	4-N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030280	-	PUBCHEM	73506219	C63H82N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAKVXIUNQHYAPX-UPKUDDMJSA-N
29185	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9235	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methoxy]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030278	-	PUBCHEM	90089727	C63H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PXWQVOUQYPMEME-NMZKVUILSA-N
29186	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9236	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethynyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030275	-	PUBCHEM	90089572	C64H81N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MZOKCLGAIIRHDG-KHFWCYFCSA-N
29187	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9237	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030273	-	PUBCHEM	90089737	C64H85N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MRQUIOMXZIGPPW-KHFWCYFCSA-N
29188	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9238	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-benzothiazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030272	-	PUBCHEM	118497975	C64H81N11O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SYZOGRWMVSXFBX-OVCCXHLHSA-N
29189	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9239	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-oxazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030270	-	PUBCHEM	73507318	C60H79N11O9	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VYZMHQWZWYAOIA-QLYDQGARSA-N
29190	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9240	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030269	-	PUBCHEM	118323269	C63H83N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LDVMHSURAWAEBW-YUTDAYPPSA-N
29191	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9241	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-1-(2-fluorophenyl)ethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030268	-	PUBCHEM	73603510	C61H80FN9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SUVGZSPIXFUCLS-NQFXVQPCSA-N
29192	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9244	(3S)-N-[(1S)-1-(2,3-Difluorophenyl)ethyl]-2-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030267	-	PUBCHEM	118715864	C61H79F2N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XKVHXUXRQUCUTL-XNSIXTBXSA-N
29193	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9242	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030266	-	PUBCHEM	73603641	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-DFNGJWONSA-N
29194	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9243	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030265	-	PUBCHEM	118715865	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-UICOXBBFSA-N
29195	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9245	4-N-[(3S)-2-[(2R)-3-[2-[3-[4-(3-Aminopropylamino)butylamino]propylamino]-2-oxoethyl]sulfanyl-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030264	-	PUBCHEM	118715866	C74H106N14O9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CIWSKTYTWYRRIW-ONVBUOODSA-N
29196	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9246	4-N-[(3S)-2-[(2R)-3-[2-[3-[3-[4-(3-Aminopropylamino)butylamino]propylamino]propylamino]-2-oxoethyl]sulfanyl-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030263	-	PUBCHEM	118715867	C77H113N15O9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZMXKIYQYKSPEKG-ZLUZKAKLSA-N
29197	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9247	4-N-[(3S)-2-[(2R)-3-[2-[3-[3-[4-(3-Aminopropylamino)butylamino]propyl-carbamimidoylamino]propylamino]-2-oxoethyl]sulfanyl-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030262	-	PUBCHEM	118715868	C78H115N17O9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GDKDASNHAMUPQR-ZLUZKAKLSA-N
29198	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9248	4-N-[(3S)-2-[(2R)-3-[2-[3-[Carbamimidoyl-[3-[carbamimidoyl-[4-[carbamimidoyl-[3-(diaminomethylideneamino)propyl]amino]butyl]amino]propyl]amino]propylamino]-2-oxoethyl]sulfanyl-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030261	-	PUBCHEM	118715869	C81H121N23O9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SLEYXAFJLKXZIB-ZLUZKAKLSA-N
29199	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2014)	25261927	224778	9249	N-[4-[3-Chloro-4-[(3S)-oxolan-3-yl]oxyanilino]thieno[2,3-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide	BDBM50102566	-	PUBCHEM	118715746	C24H28ClN5O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DHVTZWIWZWPIFU-INIZCTEOSA-N
29200	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2014)	25261927	224778	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29201	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2014)	25233084	224779	9250	8-Mercapto-octanoic acid phenylamide	8-MERCAPTO-OCTANOIC ACID PHENYLAMIDE|ZINC13609343|N-PHENYL-8-SULFANYLOCTANAMIDE|8-MERCAPTO-N-PHENYLOCTANAMIDE|BDBM50027601	-	PUBCHEM	11149404	C14H21NOS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VTVJPXWTXILBGK-UHFFFAOYSA-N
29202	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2014)	25233084	224779	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29203	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9251	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-morpholin-4-ylsulfonylethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-MORPHOLIN-4-YLSULFONYLETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053052	-	PUBCHEM	67999720	C29H34Cl2N2O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSZIUWBZPLMUNE-GCMXZSHTSA-N
29204	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9252	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-piperidin-1-ylsulfonylethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-PIPERIDIN-1-YLSULFONYLETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053051	-	PUBCHEM	67998850	C30H36Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HLRWFQSMFDJFQQ-QXMDYEBFSA-N
29205	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9253	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(methylsulfamoyl)ethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(METHYLSULFAMOYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053045	-	PUBCHEM	68000050	C26H30Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TUDCVMKUXPXOII-HLMLHLEXSA-N
29206	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9254	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(propan-2-ylsulfamoyl)ethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PROPAN-2-YLSULFAMOYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053040	-	PUBCHEM	68000097	C28H34Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OLQSAQIIKIWIRZ-YWCVFVGNSA-N
29207	111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	unknown	target	de Bruin G (2014)	25006746	224781	9255	(2S)-1-[(2S)-2-[(2-Azidoacetyl)amino]propanoyl]-N-[(2S)-1-[[(2S)-3-cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]-4,4-difluoropyrrolidine-2-carboxamide	BDBM50099953	-	PUBCHEM	118709680	C28H43F2N7O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BYGWQGGWZMNGGA-MDEFBCHOSA-N
29208	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	unknown	target	de Bruin G (2014)	25006746	224781	9256	N-[(2R)-1-[[(2S)-1-[[(2S)-3-Cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methyl-1H-indene-2-carboxamide	LU-035I|BDBM50099686	-	PUBCHEM	101874279	C36H45N3O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SIXKXOYWBKFIOX-CIEAOGCXSA-N
29209	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	unknown	target	de Bruin G (2014)	25006746	224781	9257	N-[(2R)-1-[[(2S)-1-[[(2S)-3-Cyclohexyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methyl-1H-indene-2-carboxamide	LU-015I|BDBM50099664	-	PUBCHEM	101874275	C37H44N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HCSMZVMWZMSHSC-LZNHGOJSSA-N
29210	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	unknown	target	de Bruin G (2014)	25006746	224781	9258	N-[(2R)-1-[[(2S)-3-(1H-Indol-3-yl)-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methyl-1H-indene-2-carboxamide	L-TRYPTOPHANAMIDE, N-((3-METHYL-1H-INDEN-2-YL)CARBONYL)-D-ALANYL-N-((1S)-2-((2R)-2-METHYL-2-OXIRANYL)-2-OXO-1-(PHENYLMETHYL)ETHYL)-|Q27295555|HY-123587|1416709-79-9|CS-0083586|UNII-ZI5ZER54A9|PR-924|ZI5ZER54A9|BDBM50099663	-	PUBCHEM	92135659	C37H38N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ADBUEVSHEJICCM-LZNHGOJSSA-N
29211	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	unknown	target	de Bruin G (2014)	25006746	224781	9259	Onx-0914 (PR-957)	C31H40N4O7|PR-957|Q27088204|SC-84030|HY-13207|(2S)-3-(4-METHOXYPHENYL)-N-[(2S)-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[(2S)-2-[2-(MORPHOLIN-4-YL)ACETAMIDO]PROPANAMIDO]PROPANAMIDE|(S)-3-(4-METHOXYPHENYL)-N-((S)-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)PROPANAMIDO)PROPANAMIDE|EX-A459|AS-35161|AKOS025404933|(2S)-N-[(1S)-1-BENZYL-2-[(2R)-2-METHYLOXIRAN-2-YL]-2-OXO-ETHYL]-3-(4-METHOXYPHENYL)-2-[[(2S)-2-[(2-MORPHOLINOACETYL)AMINO]PROPANOYL]AMINO]PROPANAMIDE|A12653|PR 957|ONX-0914 (PR-957)|960374-59-8|ONX 0914|ONX-0914|BCP07652|(2S)-3-(4-METHOXYPHENYL)-N-[(2S)-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]PROPANOYL]AMINO]PROPANAMIDE|CS-1625|GTPL9031|AOB87169|Y1243|S-7830|ZINC43207593|KS-00000XP8|BDBM50007203	-	PUBCHEM	23642227	C31H40N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WQAVPPWWLLVGFK-VTNASVEKSA-N
29212	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9260	[(2R,3S)-2-(2-Hydroxyethyl)-3-[4-[2-(2-methoxyethoxy)phenyl]piperazine-1-carbonyl]-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020151	-	PUBCHEM	90644648	C35H39ClF6N4O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GAWXPLJRMGISPF-AAYBCKPTSA-N
29213	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9261	[(2R,3S)-2-(2,3-Dihydroxypropyl)-3-[4-[2-(2-methoxyethoxy)phenyl]piperazine-1-carbonyl]-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020150	-	PUBCHEM	90644647	C36H41ClF6N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLKVYUYEIZLSOY-QAJMXTGNSA-N
29214	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9262	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-propyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020149	-	PUBCHEM	90644646	C36H41ClF6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOTYTBNHWCLYIW-BRMBYNPVSA-N
29215	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9263	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-prop-2-enyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone	BDBM50001929	-	PUBCHEM	23642310	C36H38F6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKOYVKQWXLFSPH-FJQKOURKSA-N
29216	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9264	2-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-5-methyl-1,3,4-oxadiazole	2-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-5-METHYL-1,3,4-OXADIAZOLE|BDBM50012598	-	PUBCHEM	67031670	C24H20Cl2F2N4O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WSYHJRPECYYALB-UHFFFAOYSA-N
29217	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9265	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazole-4-carboxamide	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOLE-4-CARBOXAMIDE|BDBM50012597	-	PUBCHEM	67032018	C22H19Cl2F2N3O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WCIBRTOQTDTZEH-UHFFFAOYSA-N
29218	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9266	1-(5-Chloro-2-methylphenyl)-5-(3-chlorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012596	-	PUBCHEM	67035866	C23H16Cl2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HGVSKSDYMUWDDZ-UHFFFAOYSA-N
29219	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9267	1-(5-Chloro-2-Methylphenyl)-5-(3-Chlorophenyl)-2-(3-Methylphenyl)-1h-Imidazole-4-Carboxylic Acid	1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-(3-METHYLPHENYL)IMIDAZOLE-4-CARBOXYLIC ACID|4OQ3|Q27453318|2V8|1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-(3-METHYLPHENYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012595	-	PUBCHEM	50996417	C24H18Cl2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UYJZPBBJELZWKZ-UHFFFAOYSA-N
29220	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9268	1-(3-Chloro-2-fluorophenyl)-5-(3-chlorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012594	-	PUBCHEM	67035746	C22H13Cl2FN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWKUHDIFHWGKSW-UHFFFAOYSA-N
29221	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9269	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-phenylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-PHENYLACETAMIDE|BDBM50012593	-	PUBCHEM	67954180	C31H26Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LVTCZQLXJGEKOF-UHFFFAOYSA-N
29222	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9270	5-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-1,3,4-oxadiazol-2-amine	5-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-1,3,4-OXADIAZOL-2-AMINE|BDBM50012592	-	PUBCHEM	67954546	C23H19Cl2F2N5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XPRXKGPGGKKGGT-UHFFFAOYSA-N
29223	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9271	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-methylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-METHYLACETAMIDE|2-{2-[4-(5-AMINO-[1,3,4]OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUORO-PHENYL)-2-CYCLOHEXYL-IMIDAZOL-1-YL]-4-CHLORO-3-FLUORO-PHENYL}-N-METHYL-ACETAMIDE|BDBM50012591	-	PUBCHEM	67032045	C26H24Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FXKYGUQUTHFCIZ-UHFFFAOYSA-N
29224	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9272	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012590	-	PUBCHEM	67954173	C22H18Cl2F2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OKZRWZNDCUYSPD-UHFFFAOYSA-N
29225	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9273	5-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-2H-tetrazole	5-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-2H-TETRAZOLE|BDBM50012589	-	PUBCHEM	67032499	C22H18Cl2F2N6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	APOKXFGOAIBPAE-UHFFFAOYSA-N
29226	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9274	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012588	-	PUBCHEM	67954174	C22H12Cl2F2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FQIJHXGZFVSBLN-UHFFFAOYSA-N
29227	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9275	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-tert-butylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-TERT-BUTYLACETAMIDE|BDBM50012587	-	PUBCHEM	60167943	C29H30Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZZSUOGVLVLJPR-UHFFFAOYSA-N
29228	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9276	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-cyclohexylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-CYCLOHEXYLACETAMIDE|BDBM50012586	-	PUBCHEM	67034825	C31H32Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SMUUKZTVPGSBEE-UHFFFAOYSA-N
29229	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Pan W (2014)	24656661	224784	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29230	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Pan W (2014)	24656661	224784	9263	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-prop-2-enyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone	BDBM50001929	-	PUBCHEM	23642310	C36H38F6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKOYVKQWXLFSPH-FJQKOURKSA-N
29231	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9277	(2S)-N-[(1S)-2-[(3Ar,7aS)-6-(2-phenylethyl)-3,3a,4,5,7,7a-hexahydro-2H-pyrrolo[2,3-c]pyridin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	CS-0006862|LBW242|867324-12-7|HY-15519|(2S)-N-[(1S)-2-[(3AR,7AS)-6-(2-PHENYLETHYL)-3,3A,4,5,7,7A-HEXAHYDRO-2H-PYRROLO[2,3-C]PYRIDIN-1-YL]-1-CYCLOHEXYL-2-OXOETHYL]-2-(METHYLAMINO)PROPANAMIDE|BDBM50364485	-	PUBCHEM	11503417	C27H42N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HCSMRSHIIKPNAK-LSAVBLLPSA-N
29232	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9278	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(2-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001139	-	PUBCHEM	90654412	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VUHJRMSITOPODU-JELQSWKKSA-N
29233	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9279	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Hydroxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001138	-	PUBCHEM	90654411	C24H36N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNEFKNCSOQRMCU-CRDRRFEFSA-N
29234	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9280	(2S)-N-[(2S,7R,9S,13S)-4-[2-(3-Methoxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001136	-	PUBCHEM	90654409	C25H38N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PTCUWTLAVOGZOF-YFVPBJFGSA-N
29235	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9281	(2S)-N-[(2S,7R,9S,13S)-4-[2-(2-Methoxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001135	-	PUBCHEM	90654408	C25H38N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NDQMUJBKPCHPFP-WFMNFSIZSA-N
29236	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9282	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Fluorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001134	-	PUBCHEM	90654407	C24H35FN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NPUNAPHKJPGXNY-ORDMVQLLSA-N
29237	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9283	(2S)-N-[(2S,7R,9S,13S)-4-[2-(2-Fluorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001133	-	PUBCHEM	90654406	C24H35FN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HPONQTAHVJCUCR-CRDRRFEFSA-N
29238	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9284	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Bromophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001132	-	PUBCHEM	90654405	C24H35BrN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCFKWSBDCRMWRK-ORDMVQLLSA-N
29239	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9285	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-(2-phenylethyl)-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001131	-	PUBCHEM	90654404	C24H36N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LTFVDAMNPLQBHE-WFMNFSIZSA-N
29240	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9286	(6S,9Ar)-2,2-dimethyl-6-[[(2S)-2-(methylamino)propanoyl]amino]-N-(5-methyl-2-phenylpyrazol-3-yl)-5-oxo-3,6,7,8,9,9a-hexahydro-[1,3]thiazolo[3,2-a]azepine-3-carboxamide	BDBM50001130	-	PUBCHEM	90654403	C25H34N6O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RBLGKKZTMVKMNE-CPCSJTIGSA-N
29241	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9287	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-[6-[2-[(2S,7R,9S,13S)-13-[[(2S)-2-(methylamino)propanoyl]amino]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-4-yl]-2-oxo-1-phenylethoxy]hexa-2,4-diynoxy]-2-phenylacetyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001129	-	PUBCHEM	86276147	C54H70N8O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CNHIJRXXUZNFIO-TXLCXPLDSA-N
29242	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9288	Phenyl (2S,7R,9S,13S)-13-[[(2S)-2-(methylamino)propanoyl]amino]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecane-4-carboxylate	BDBM50001125	-	PUBCHEM	90654399	C23H32N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	COOWRGHTGIMRRI-SQIBXOBRSA-N
29243	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9289	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-(2-phenylacetyl)-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001101	-	PUBCHEM	90654394	C24H34N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RMWMSAOQRVQSSL-DARKYYSBSA-N
29244	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9290	(2S)-N-[(2S,7R,9S,13S)-4-[2-(1H-Indol-3-yl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001083	-	PUBCHEM	90654382	C26H37N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NXKKLSUXQLAFFE-SOFANIRLSA-N
29245	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9291	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-[2-[4-(trifluoromethyl)phenyl]ethyl]-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001081	-	PUBCHEM	90654380	C25H35F3N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CBUKBSAVVSVBEX-ORDMVQLLSA-N
29246	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9292	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(4-nitrophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001080	-	PUBCHEM	90654379	C24H35N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AQTFKDCKLOSLNK-ORDMVQLLSA-N
29247	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9293	(2S)-N-[(2S,7R,9S,13S)-4-[2-(3,4-Dichlorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001079	-	PUBCHEM	90654378	C24H34Cl2N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FAPNSKGNSXRVLR-CBJPPDNLSA-N
29248	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9294	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Chlorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001078	-	PUBCHEM	90654377	C24H35ClN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DOFKWVQMIJUKCV-ORDMVQLLSA-N
29249	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9295	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(4-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001077	-	PUBCHEM	90654376	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AQFHGNZPIGAZGV-JELQSWKKSA-N
29250	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9296	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(3-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001076	-	PUBCHEM	90654375	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AVBZMSWFBFFJGJ-JELQSWKKSA-N
29251	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9287	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-[6-[2-[(2S,7R,9S,13S)-13-[[(2S)-2-(methylamino)propanoyl]amino]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-4-yl]-2-oxo-1-phenylethoxy]hexa-2,4-diynoxy]-2-phenylacetyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001129	-	PUBCHEM	86276147	C54H70N8O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CNHIJRXXUZNFIO-TXLCXPLDSA-N
29252	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Gonzalez AZ (2014)	24601644	224786	9297	2-[2-[[(3R,5R,6S)-1-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl]-1,3-thiazol-5-yl]acetic acid	(2-{[(3R,5R,6S)-1-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]METHYL}-1,3-THIAZOL-5-YL)ACETIC ACID|Q27453278|AM-6761|2U0|4ODE|BDBM50008748	-	PUBCHEM	73386675	C33H37Cl2FN2O5S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNLHOKSDTBAERS-CWIPYCOQSA-N
29253	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Gonzalez AZ (2014)	24548297	224787	9298	2-[(2R,5R,6R)-4-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid	Q27453272|CS-0012311|AM-8735|[(2R,5R,6R)-4-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-3-OXOMORPHOLIN-2-YL]ACETIC ACID|4OBA|2TW|2-[(2R,5R,6R)-4-[(1S)-2-TERT-BUTYLSULFONYL-1-CYCLOPROPYLETHYL]-6-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-3-OXOMORPHOLIN-2-YL]ACETIC ACID|HY-12734|BDBM50007638	-	PUBCHEM	71544420	C27H31Cl2NO6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZTMSSDQFJNEUNG-WMMXXEOUSA-N
29254	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Sun D (2014)	24456472	224788	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29255	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Sun D (2014)	24456472	224788	9299	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	Q27451341|AM-8553|{(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(2S,3S)-2-HYDROXYPENTAN-3-YL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(2S,3S)-2-HYDROXYPENTAN-3-YL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((2S,3S)-2-HYDROXYPENTAN-3-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|0R3|BDBM50388626	-	PUBCHEM	56965957	C25H29Cl2NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YUALYRLIFVPOHL-VPLUBSIMSA-N
29256	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Huang Q (2014)	24432909	224789	9300	Unii-76pnd635L1	PF-06439015|(2R)-2-[5-[6-AMINO-5-[(1R)-1-[5-FLUORO-2-(TRIAZOL-2-YL)PHENYL]ETHOXY]PYRIDIN-3-YL]-4-METHYL-1,3-THIAZOL-2-YL]PROPANE-1,2-DIOL.|(2R)-2-[5-[6-AMINO-5-[(1R)-1-[5-FLUORO-2-(TRIAZOL-2-YL)PHENYL]ETHOXY]PYRIDIN-3-YL]-4-METHYL-1,3-THIAZOL-2-YL]PROPANE-1,2-DIOL|4CD0|(2R)-2-(5-(6-AMINO-5-((1R)-1-(5-FLUORO-2-(2H-1,2,3-TRIAZOL-2-YL)PHENYL)ETHOXY)-3-PYRIDINYL)-4-METHYL-2-THIAZOLYL)-1,2-PROPANEDIOL|1549629-82-4|AWJ|P-355|Q27076827|76PND635L1|ZINC98050687|1,2-PROPANEDIOL, 2-(5-(6-AMINO-5-((1R)-1-(5-FLUORO-2-(2H-1,2,3-TRIAZOL-2-YL)PHENYL)ETHOXY)-3-PYRIDINYL)-4-METHYL-2-THIAZOLYL)-, (2R)-|PF 06439015|COMPOUND 8E [PMID: 24432909]|GTPL8137|NCGC00485046-01|UNII-76PND635L1|BDBM50448785	-	PUBCHEM	72710568	C22H23FN6O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DIXMBHMNEHPFCX-MCMMXHMISA-N
29257	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Blasdel LK (2013)	24269479	224790	9301	(1R,4R,5S)-4-(2-Chloroethyl)-1-[(S)-cyclohexyl(hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione	SALINOSPORAMIDE X1|BDBM50444464	-	PUBCHEM	11243977	C15H22ClNO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OJZFVOGTYOBPKD-GVARAGBVSA-N
29258	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Blasdel LK (2013)	24269479	224790	9302	(1R,4R,5S)-4-(3-Chloropropyl)-1-[(S)-cyclohexyl(hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione	BDBM50444463	-	PUBCHEM	72724741	C16H24ClNO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YQXBYNPDPJTCPP-APYUEPQZSA-N
29259	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Blasdel LK (2013)	24269479	224790	9303	(1R,4R,5S)-4-(2-Chloroethyl)-1-[(S)-cyclopropyl(hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione	BDBM50444462	-	PUBCHEM	72724804	C12H16ClNO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VKEICTONBXTKAQ-OSTYVCCYSA-N
29260	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Blasdel LK (2013)	24269479	224790	8396	Marizomib	(1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-3-hydroxy-5-methyl-6-oxa-2-azabicyclo[3.2.0]hept-2-en-7-one|(1R,4R,5S)-4-(2-Chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-yl(hydroxy)methyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione|(-)-salinosporamide A|marizomib|6-Oxa-2-azabicyclo[3.2.0]heptane-3,7-dione, 4-(2-chloroethyl)-1-[(S)-(1S)-2-cyclohexen-1-ylhydroxymethyl]-5-methyl-, (1R,4R,5S)-|Salinosporamide A|9205|703P9YDP7F|BDBM50398608	-	CHEMSPIDER	9522473	C15H20ClNO4	small molecule	-	437742-34-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NGWSFRIPKNWYAO-SHTIJGAHSA-N
29261	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Shiokawa Z (2013)	24169315	212886	9304	(3S,10As)-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)butanoyl]amino]acetyl]-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indole-3-carboxamide	Q27452924|(3S,10AS)-2-[(2S)-2-CYCLOHEXYL-2-[[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO]ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-3,4,10,10A-TETRAHYDRO-1H-PYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE|(3S,10AS)-2-[(2S)-2-CYCLOHEXYL-2-{[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO}ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-1,2,3,4,10,10A-HEXAHYDROPYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE|2DY|BDBM50443812	-	PUBCHEM	60198985	C34H45N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TYXHMZBEDPKUQY-HDFVOGAFSA-N
29262	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Shiokawa Z (2013)	24169315	212886	9305	(3S,10As)-8-cyano-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)butanoyl]amino]acetyl]-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indole-3-carboxamide	(3S,10AS)-8-CYANO-2-[(2S)-2-CYCLOHEXYL-2-[[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO]ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-3,4,10,10A-TETRAHYDRO-1H-PYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE|BDBM50443808	-	PUBCHEM	60198193	C35H44N6O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XIVQNOQUXQCLEI-NSKQSPGJSA-N
29263	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Shiokawa Z (2013)	24169315	212886	9306	(3S,10As)-8-chloro-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)butanoyl]amino]acetyl]-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indole-3-carboxamide	(3S,10AS)-8-CHLORO-2-[(2S)-2-CYCLOHEXYL-2-[[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO]ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-3,4,10,10A-TETRAHYDRO-1H-PYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE|(3S)-N-[(4R)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4BETA-YL]-2-[(S)-[(2S)-2-(METHYLAMINO)BUTANOYL]AMINOCYCLOHEXYLACETYL]-8-CHLORO-1,2,3,4,10,10AALPHA-HEXAHYDROPYRAZINO[1,2-A]INDOLE-3ALPHA-CARBOXAMIDE|BDBM50443807	-	PUBCHEM	60198300	C34H44ClN5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XDBOAVJEQWZFNY-HDFVOGAFSA-N
29264	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Shiokawa Z (2013)	24169315	212886	9307	(3S,10As)-6,8-dichloro-2-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)butanoyl]amino]acetyl]-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indole-3-carboxamide	(3S,10AS)-6,8-DICHLORO-2-[(2S)-2-CYCLOHEXYL-2-[[(2S)-2-(METHYLAMINO)BUTANOYL]AMINO]ACETYL]-N-[(4R)-3,4-DIHYDRO-2H-CHROMEN-4-YL]-3,4,10,10A-TETRAHYDRO-1H-PYRAZINO[1,2-A]INDOLE-3-CARBOXAMIDE|BDBM50443806	-	PUBCHEM	72736709	C34H43Cl2N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KSALHYXGSMEPIV-MYEJIDBFSA-N
29265	110309	4139	-	MARK1	MARK|Par-1c|Par1c	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29266	110309	4139	-	MARK1	MARK|Par-1c|Par1c	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29267	117727	26524	-	LATS2	KPM	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29268	117727	26524	-	LATS2	KPM	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29269	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29270	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29271	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
29272	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29273	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29274	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29275	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29276	114491	9024	HUSSY-12	BRSK2	C11orf7|PEN11B|SAD1|SADA|STK29	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29277	114491	9024	HUSSY-12	BRSK2	C11orf7|PEN11B|SAD1|SADA|STK29	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29278	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29279	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29280	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29281	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29282	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
29283	127260	150094	-	SIK1	MSK|SIK|SNF1LK	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29284	127260	150094	-	SIK1	MSK|SIK|SNF1LK	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29285	127260	150094	-	SIK1	MSK|SIK|SNF1LK	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
29286	110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29287	110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29288	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29289	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29290	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wells JA (2007)	18075579	224792	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29291	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wells JA (2007)	18075579	224792	9309	DI-Chloro-benzo-diazepine	BENZODIAZEPINEDIONE, 1|(2S)-(4-CHLOROPHENYL)[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ETHANOIC ACID|BMCL163310 COMPOUND 1|Q27459367|TDP-222669|(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|DIZ|(2S)-2-(4-CHLOROPHENYL)-2-[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,3-DIHYDRO-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|1T4E|JNJ-38732382|DI-CHLORO-BENZO-DIAZEPINE|BDBM31285	-	PUBCHEM	656933	C23H15Cl2IN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQEQUYKKMMKSSX-PMACEKPBSA-N
29292	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi Q (2007)	18029178	224793	9310	3-[4-[3-[(1R)-1-[(5-Chloro-3-methyl-1-benzothiophene-2-carbonyl)amino]ethyl]-5-fluorophenoxy]-2-ethylphenyl]propanoic acid	(R)-3-(4-(3-(1-(5-CHLORO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXAMIDO)ETHYL)-5-FLUOROPHENOXY)-2-ETHYLPHENYL)PROPANOIC ACID|BDBM50227754	-	PUBCHEM	44434362	C29H27ClFNO4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WQCJKMGDGUHOFD-QGZVFWFLSA-N
29293	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi Q (2007)	18029178	224793	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29294	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Rydzewski RM (2006)	16686537	132619	9311	Benzyl N-[(2S,3S)-1-[[(2S)-4-(2,2-dimethylpropylamino)-1-[[(2S)-1-[[(E,3S)-5-methyl-1-methylsulfonylhex-1-en-3-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamate	CBZ-ILE-NEOPENTYLASN-ALA-LEUVSME|BDBM50186721	-	PUBCHEM	11542118	C34H55N5O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LHKDGGRUJJWIPS-NBSSRRDYSA-N
29295	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Rydzewski RM (2006)	16686537	132619	9312	Tert-butyl (4S)-5-[[(2S)-1-[[(E,3S)-5-methyl-1-methylsulfonylhex-1-en-3-yl]amino]-1-oxopropan-2-yl]amino]-4-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate	CBZ-ILE-GLU(OTBU)-ALA-LEUVSME|BDBM50186709	-	PUBCHEM	11556651	C34H54N4O9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZUSJEPYDXSSIAZ-NHVLHDLVSA-N
29296	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Rydzewski RM (2006)	16686537	132619	9313	(2S)-N'-(2,2-Dimethylpropyl)-N-[(2S)-1-[[(E,3S)-5-methyl-1-methylsulfonylhex-1-en-3-yl]amino]-1-oxopropan-2-yl]-2-[(4-methylphenyl)sulfonylamino]butanediamide	PTOSYL-NEOPENTYLASN-ALA-LEUVSME|BDBM50186696	-	PUBCHEM	11671614	C27H44N4O7S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SJRZTCJLZWVMBR-FGXWTBHQSA-N
29297	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9314	2-[[2-[Acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[3-hydroxy-1-[[4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylpentanamide	AKOS032947211|134381-21-8|BDBM50370717	-	PUBCHEM	9915668	C28H50N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DOGIDQKFVLKMLQ-UHFFFAOYSA-N
29298	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9315	Benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(E,3S)-5-methyl-1-methylsulfonylhex-1-en-3-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate	HMS1362N19|NCGC00163486-01|BENZYL (S)-4-METHYL-1-((S)-4-METHYL-1-((S,E)-5-METHYL-1-(METHYLSULFONYL)HEX-1-EN-3-YLAMINO)-1-OXOPENTAN-2-YLAMINO)-1-OXOPENTAN-2-YLCARBAMATE|CARBOBENZYLOXY-LEU-LEU-LEU-VINYL SULFONE|BRD-K15935639-001-02-0|HMS3403N19|BCBCMAP01_000228|193482-47-2|Z-LEU3-VS|L-LEUCINAMIDE, N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N-[(1S)-3-METHYL-1-[(E)-2-(METHYLSULFONYL)ETHENYL]BUTYL]-|HMS1990N19|IDI1_002214|BSPBIO_001238|NCGC00163486-02|L-LEUCINAMIDE, N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N-[(1S)-3-METHYL-1-[(1E)-2-(METHYLSULFONYL)ETHENYL]BUTYL]- (9CI)|HMS1792N19|BDBM50185157	-	PUBCHEM	5497183	C28H45N3O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DHLFJZAIZCMWEO-JDGFICQVSA-N
29299	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Dropinski JF (2005)	16153845	224795	9316	1-(4-Tert-butylphenyl)-3-[3-(trifluoromethyl)phenoxy]indole-2-carboxylic acid	1-(4-TERT-BUTYL-PHENYL)-3-(3-TRIFLUOROMETHYL-PHENOXY)-1H-INDOLE-2-CARBOXYLIC ACID|BDBM50173359	-	PUBCHEM	11546956	C26H22F3NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QEDIKMQCSOVILD-UHFFFAOYSA-N
29300	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Grasberger BL (2005)	15715460	224796	9309	DI-Chloro-benzo-diazepine	BENZODIAZEPINEDIONE, 1|(2S)-(4-CHLOROPHENYL)[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ETHANOIC ACID|BMCL163310 COMPOUND 1|Q27459367|TDP-222669|(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|DIZ|(2S)-2-(4-CHLOROPHENYL)-2-[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,3-DIHYDRO-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|1T4E|JNJ-38732382|DI-CHLORO-BENZO-DIAZEPINE|BDBM31285	-	PUBCHEM	656933	C23H15Cl2IN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQEQUYKKMMKSSX-PMACEKPBSA-N
29301	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Bao J (2005)	15603971	224797	9317	[(1S,8R,9R,10S,12R,13R)-9,10-Diacetyloxy-8-[(1R)-1-acetyloxyethyl]-16-[(2R)-2-(2-ethoxyphenyl)propyl]-16-hydroxy-1,12,15-trimethyl-6-oxatetracyclo[9.8.0.02,8.012,17]nonadeca-3,14-dien-13-yl] acetate	ACETICACID(R)-1-{(4R,4AR,5S,6R,6AR,11BS)-4,5,6-TRIACETOXY-1-[2-((R)-2-ETHOXY-PHENYL)-PROPYL]-1-HYDROXY-2,4A,11B-TRIMETHYL-1,2,3,4,4A,4B,5,6,9,11A,11B,12,13,13A-TETRADECAHYDRO-8-OXA-CYCLOHEPTA[A]PHENANTHREN-6A-YL}-ETHYL ESTER|BDBM50158218	-	PUBCHEM	44388853	C42H58O11	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UGQIUGDLIPCZDN-CHRSBYMISA-N
29302	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Bao J (2005)	15603971	224797	9318	Correloid	CORRELOID|BDBM50158201	-	PUBCHEM	44389018	C40H52O16	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VKDXHXWBOARFPD-MDAQDJAWSA-N
29303	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Nikolovska-Coleska Z (2004)	15115387	212873	9319	2-[[(2S)-5-Amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]-6-[[2-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-6-(3-hydroxy-6-oxoxanthen-9-yl)benzoyl]amino]-3-methylhexanoic acid	BDBM50145772	-	PUBCHEM	44460525	C63H75N13O17	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PCMHILZLYCFWKH-LDZDWOFMSA-N
29304	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	unknown	target	Nikolovska-Coleska Z (2004)	15115387	212873	9320	(2S)-6-Amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2R)-1-[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid	6-AMINO-2-[(S)-2-((S)-2-{(S)-2-[((R)-{1-[(S)-2-((S)-2-AMINO-PROPIONYLAMINO)-5-GUANIDINO-1-OXO-PENTYL]-PYRROLIDIN-2-YL}-OXO-METHYL)-AMINO]-1-OXO-3-PHENYL-PROPYLAMINO}-1-OXO-PROPYLAMINO)-4-CARBAMOYL-1-OXO-BUTYLAMINO]-HEXANOIC ACID|BDBM50145770	-	PUBCHEM	44460459	C37H60N12O9	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CGCXTKPVWBLRRX-AGFHODQESA-N
29305	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Miao S (2003)	12643934	224798	9321	BDBM50125526	-	-	CHEMBL	CHEMBL16683	C25H31N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DWUAIAOAUXYSMK-WBANQOEISA-N
29306	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	unknown	target	He Y (2017)	28135237	224799	9322	A-395	(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine|2089148-72-9|GTPL9525|HY-101512|CS-0021615|J3.609.234C|(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]pyrrolidin-3-amine|rel-(3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine|rac-(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine (4)|BDBM223987|BDBM50241662	-	PUBCHEM	123132213	C26H35FN4O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CMZCLMBPMLFJJU-YVEFUNNKSA-N
29307	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	unknown	target	Qi W (2017)	28135235	224800	9323	N-(Furan-2-Ylmethyl)-8-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[4,3-C]pyrimidin-5-Amine	KS-00000U9I|N-(FURAN-2-YLMETHYL)-8-(4-(METHYLSULFONYL)PHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|S8496|AK684382|CS-6391|N-[(FURAN-2-YL)METHYL]-8-(4-METHANESULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|EX-A1724|AS-74203|N-(FURAN-2-YLMETHYL)-8-(4-METHYLSULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|EED-226|AKOS030632048|2083627-02-3|AC-29879|BCP19849|CCG-268284|MAK683(EED226/COMPOUND 43)|J3.609.221A|SB40406|ACN-051243|EED226|HY-101117|BDBM225230	-	PUBCHEM	123132228	C17H15N5O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DYIRSNMPIZZNBK-UHFFFAOYSA-N
29308	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nalawansha DA (2017)	27977115	224801	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29309	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nalawansha DA (2017)	27977115	224801	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29310	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Miyake Y (2016)	27454931	224802	9324	(2E,4S,5E)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,5-dienamide	S-TSA|BDBM197337	-	PUBCHEM	122198566	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ALCVRKZFLFWUAZ-CSFUQHBASA-N
29311	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Miyake Y (2016)	27454931	224802	9325	(2E,4R,5E)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,5-dienamide	R-TSA|BDBM197336	-	PUBCHEM	122198565	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ALCVRKZFLFWUAZ-LSSUCPAZSA-N
29312	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li J (2016)	27235003	224803	4802	Belinostat	UNII-F4H96P17NZ|NSC-726630|ZINC3818726|ABP000140|866323-14-0|SC-71101|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|SW219445-1|NSC726630|BELEODAQ|BCPP000351|EX-A180|PX 105684|QCR-181|BCP01741|BRD-K17743125-001-01-9|GTPL7496|(E)-N-HYDROXY-3-(3-(N-PHENYLSULFAMOYL)PHENYL)ACRYLAMIDE|BELINOSTAT - PXD101|SB16466|CC-489|AOB87787|BELINOSTAT|AX8144528|MLS006011091|AC-25046|AB0007889|BELINOSTAT (PXD101)|BELINOSTAT,PXD101, PX105684|W-5363|(E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|414864-00-9|D08870|(E)-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENEHYDROXAMIC ACID|BELINOSTAT [USAN:INN]|SMR004702879|Q4882925|E-BELINOSTAT|BELINOSTAT (PXD101)|PXD101|PXD 101|N-HYDROXY-3-(3-PHENYLSULPHAMOYLPHENYL)ACRYLAMIDE|API0003555|BELINOSTAT (USAN/INN)|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]ACRYLAMIDE|BELEODAQ (TN)|PUBCHEM22405|NCGC00263155-05|(E)-N-HYDROXY-3-(3-PHENYLSULFAMOYL-PHENYL)-ACRYLAMIDE|PXD-101|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PR|S1085|LS41098|PX-105684|BELINOSTAT PH3|N-HYDROXY-3-(3-PHENYLSULFAMOYLPHENYL)ACRYLAMIDE|EC-000.2286|BELINOSTAT/PXD101,PX105684/|5OG|DTXSID60194378|2-PROPENAMIDE, N-HYDROXY-3-(3-((PHENYLAMINO)SULFONYL)PHENYL)-, (2E)-|BCP9000386|PX105684|F4H96P17NZ|N-HYDROXY-3-[(PHENYLAMINO)SULFONYL]-TRANS-CINNAMAMIDE|AS-17068|BELINOSTAT(RANDOM CONFIGURATION)|A25012|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE|AKOS025401741|N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE|CCG-208758|2-PROPENAMIDE, N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-, (2E)-|DB05015|J-523584|BDBM25150	beleodaq	DRUGBANK	DB05015	C15H14N2O4S	small molecule	L01XX49	866323-14-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NCNRHFGMJRPRSK-MDZDMXLPSA-N
29313	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li J (2016)	27235003	224803	9326	(E)-N-Hydroxy-3-[3-[[(1S)-2-(naphthalen-1-ylamino)-2-oxo-1-phenylethyl]sulfamoyl]phenyl]prop-2-enamide	(S,E)-N-HYDROXY-3-(3-(N-(2-(NAPHTHALEN-1-YLAMINO)-2-OXO-1-PHENYLETHYL)SULFAMOYL)PHENYL)ACRYLAMIDE (10S)|BDBM198192	-	PUBCHEM	122198640	C27H23N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JCEFNCFZXQDHRY-ZOGILVBSSA-N
29314	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Sundberg TB (2016)	27224444	224804	9327	3-(2-Chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one	BCP20631|YKL-05-099 (5)|CS-6458|SB18778|YKL-05-099|1936529-65-5|HY-101147|ZINC669678976|BDBM192716	-	PUBCHEM	121596782	C32H34ClN7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VQINULODWGEVBB-UHFFFAOYSA-N
29315	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Sundberg TB (2016)	27224444	224804	9328	3-(2-Chloro-6-methylphenyl)-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one	YKL-05-096 (4)|BDBM192715	-	PUBCHEM	121596781	C31H33ClN8O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JPYJYNNIQRTRFF-UHFFFAOYSA-N
29316	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Sundberg TB (2016)	27224444	224804	9329	3-(2-Chloro-6-methylphenyl)-1-(5-methoxypyridin-2-yl)-7-[4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one	YKL-05-095 (3)|BDBM192714	-	PUBCHEM	121596780	C30H31ClN8O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VGLSPBMOSOBBBC-UHFFFAOYSA-N
29317	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Sundberg TB (2016)	27224444	224804	9330	3-(2-Chloro-6-methylphenyl)-1-(2,4-dimethoxyphenyl)-7-[4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one	HG-9-91-01 DERIVATIVE, 2|BDBM192713	-	PUBCHEM	121596779	C32H34ClN7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WBAFRLZXKALIGS-UHFFFAOYSA-N
29318	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Sundberg TB (2016)	27224444	224804	9331	CID 78357808	HG-9-91-01 (1)|HG-9-91-01 (SIK INHIBITOR 1)|HY-15776|S8393|NCGC00378591-01|EX-A1279|N-(2,4-DIMETHOXYPHENYL)-N'-(2,6-DIMETHYLPHENYL)-N-{6-[4-(4-METHYLPIPERAZIN-1-YL)ANILINO]PYRIMIDIN-4-YL}UREA|1-(2,4-DIMETHOXYPHENYL)-3-(2,6-DIMETHYLPHENYL)-1-[6-[4-(4-METHYLPIPERAZIN-1-YL)ANILINO]PYRIMIDIN-4-YL]UREA|SIK INHIBITOR 1; HG 9-91-01; HG9-91-01; HG99101; HG-99101; HG 99101|ZINC147474927|CS-1749|SIK INHIBITOR 1|1456858-58-4|GTPL8049|HG-9-91-01|BCP25041|Q27077982|1-(2,4-DIMETHOXYPHENYL)-3-(2,6-DIMETHYLPHENYL)-1-(6-((4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO)PYRIMIDIN-4-YL)UREA|BDBM192712	-	PUBCHEM	78357808	C32H37N7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UYUHRKLITDJEHB-UHFFFAOYSA-N
29319	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29320	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	9332	N-Hydroxy-4-[2-[(E)-2-phenylethenyl]-1,3-thiazol-4-yl]butanamide	ONC(CCCC=1N=C(SC=1)\C=C\C1=CC=CC=C1)=O|BDBM50156678	-	PUBCHEM	102514716	C15H16N2O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HJPIJALRLZVGMS-MDZDMXLPSA-N
29321	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29322	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Flick AC (2016)	27020685	224806	9333	Lobeglitazone sulfate	CKD 501|LOBEGLITAZONE SULFATE|CKD-501|2,4-THIAZOLIDINEDIONE, 5-((4-(2-((6-(4-METHOXYPHENOXY)-4- PYRIMIDINYL)METHYLAMINO)ETHOXY)PHENYL)METHYL)-, SULFATE (1:1)|SB16870|Q27271778|BDBM50152829	-	PUBCHEM	15951505	C24H26N4O9S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IFBYQAMJTBOBHB-UHFFFAOYSA-N
29323	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Waszkielewicz AM (2016)	26988801	224807	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29324	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9334	[(1S)-1-[[3-(3-Fluorophenyl)-3-[[(1S)-1,2,3,4-tetrahydronaphthalene-1-carbonyl]amino]propanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160869	-	PUBCHEM	127032443	C25H32BFN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GVCLUQUSDQUHGE-OCESARCHSA-N
29325	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9335	[(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-(5,6,7,8-tetrahydronaphthalene-1-carbonylamino)propanoyl]amino]butyl]boronic acid	BDBM50160868	-	PUBCHEM	44190247	C25H33BN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MZHTUAPXZCUHOQ-GOTSBHOMSA-N
29326	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9336	[(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-[[(1S)-1,2,3,4-tetrahydronaphthalene-1-carbonyl]amino]propanoyl]amino]butyl]boronic acid	BDBM50160867	-	PUBCHEM	44191199	C25H33BN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HLDAUCRRBXUURL-VABKMULXSA-N
29327	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9337	[(1R)-1-[[(2S)-2-(Cyclopentanecarbonylamino)-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160790	-	PUBCHEM	127032450	C20H31BN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HSLNJWMBARSHCF-ROUUACIJSA-N
29328	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9338	[(1R)-1-[[(2S)-2-(3,3-Dimethylbutanoylamino)-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160783	-	PUBCHEM	127031260	C20H33BN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JHFWWIFBVREJLE-IRXDYDNUSA-N
29329	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9339	[(1R)-1-[[(2S)-2-(Butanoylamino)-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160781	-	PUBCHEM	127032449	C18H29BN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HWPLIQKUQGRWFY-HOTGVXAUSA-N
29330	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9340	[(1R)-1-[[(2S)-2-(3-Methoxypropanoylamino)-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160780	-	PUBCHEM	127032448	C18H29BN2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HZJJGJFERHRLCB-HOTGVXAUSA-N
29331	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	9341	[(1R)-1-[[(2S)-2-[(2-Methoxyacetyl)amino]-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid	BDBM50160778	-	PUBCHEM	127032447	C17H27BN2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FYRGCNALHUEGIG-GJZGRUSLSA-N
29332	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Shi J (2016)	26965867	224808	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
29334	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Simov V (2016)	26927423	224809	9342	BDBM50152595	-	-	CHEMBL	CHEMBL3780091	C18H21N5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLWGOAGEDWMEBT-TXEJJXNPSA-N
29335	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Simov V (2016)	26927423	224809	9342	BDBM50152595	-	-	CHEMBL	CHEMBL3780091	C18H21N5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLWGOAGEDWMEBT-TXEJJXNPSA-N
29336	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Mariano M (2016)	26896709	224810	4571	5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione	5-(6-QUINOXALINYLMETHYLENE)-2,4-THIAZOLIDINEDIONE|ZINC12504504|S1410|2A5U|SR-02000000919|GTPL6023|(5Z)-5-(QUINOXALIN-6-YLMETHYLIDENE)-1,3-THIAZOLIDINE-2,4-DIONE|ABP000101|AOB3848|AS605240|NCGC00261632-01|BCP9000323|5-QUINOXALIN-6-YLMETHYLENETHIAZOLIDINE-2,4-DIONE|BCP02097|CCG-101300|1287651-14-2|J-516278|HMS3650I15|AS 605240,5-(6-QUINOXALINYLMETHYLENE)-2,4-THIAZOLIDINE-2,4-DIONE|(Z)-5-(QUINOXALIN-6-YLMETHYLENE)THIAZOLIDINE-2,4-DIONE|AS 605240|HMS3262N16|SDCCGSBI-0086699.P002|TOX21_500947|AS-605240/AS605240|CC-118|LP00947|5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE|Q27088381|PI 3-KGAMMA INHIBITOR|QYT|648450-29-7|DB04769|SR-02000000919-2|HY-10109|5-[(QUINOXALIN-6-YL)METHYLIDENE]-1,3-THIAZOLIDINE-2,4-DIONE|BRD-K76773351-001-01-9|(5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE|CS-0084|AS605240, >=98% (HPLC)|5-(6-QUINOXALINYLMETHYLENE)-2,4-THIAZOLIDINE-2,4-DIONE|5-(QUINOXALIN-6-YLMETHYLENE)THIAZOLIDINE-2,4-DIONE|SB19245|AKOS024457698|AS-16768|W-5475|NCGC00186030-01|AS-605240|PI 3-KG INHIBITOR|HMS3229I19|BDBM50324735	-	DRUGBANK	DB04769	C12H7N3O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SQWZFLMPDUSYGV-POHAHGRESA-N
29337	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Mariano M (2016)	26896709	224810	9343	(3E)-3-(1,3-Benzothiazol-6-ylmethylidene)oxolan-2-one	BDBM50154348	-	PUBCHEM	127032014	C12H9NO2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FMOOGIYSVBVFIT-WEVVVXLNSA-N
29338	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Mariano M (2016)	26896709	224810	9344	(5Z)-5-(Quinolin-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	5-[1-QUINOLIN-6-YL-METH-(Z)-YLIDENE]-2-THIOXO-THIAZOLIDIN-4-ONE|(5Z)-5-(QUINOLIN-6-YLMETHYLIDENE)-2-SULFANYLIDENE-1,3-THIAZOLIDIN-4-ONE|ZINC9908493|BDBM50154342	-	PUBCHEM	11666231	C13H8N2OS2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZFGAUFCQRUSRCF-XFFZJAGNSA-N
29339	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9345	5-Benzyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151283	-	PUBCHEM	126582837	C20H18F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JJZFDILZILDRTQ-UHFFFAOYSA-N
29340	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9346	5-Cyclopropyl-2-(5-methyl-1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151282	-	PUBCHEM	126582839	C17H18F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GJSCCYDUKNGSLB-UHFFFAOYSA-N
29341	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9347	5-Cyclopropyl-2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151281	-	PUBCHEM	126582843	C20H22F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZUPRHDPCDWVJDA-UHFFFAOYSA-N
29342	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9348	5-(2-Methylpropyl)-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151280	-	PUBCHEM	126582841	C17H20F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AZLBBFOVLFWKTC-UHFFFAOYSA-N
29343	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9349	5-Cyclopropyl-2-(1,3-thiazol-2-yl)-N-(5,5,5-trifluoro-4-oxopentyl)-1,3-thiazole-4-carboxamide	BDBM50151278	-	PUBCHEM	126582908	C15H14F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVCSQKKFUYQSGT-UHFFFAOYSA-N
29344	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9350	5-Cyclopropyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151277	-	PUBCHEM	91938063	C16H16F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OHRUWOKDVPCLPC-UHFFFAOYSA-N
29345	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9351	5-Cyclopropyl-N-[5-(hydroxyamino)-5-oxopentyl]-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide	BDBM50020897	-	PUBCHEM	71468161	C15H18N4O3S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MVJAEZIEZVJAFM-UHFFFAOYSA-N
29346	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9352	3-Pyrazin-2-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144216	-	PUBCHEM	127028943	C14H19N5OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GYWQCXUVPDWXRB-UHFFFAOYSA-N
29347	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9353	3-(1H-Indol-3-yl)-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144214	-	PUBCHEM	137174935	C18H22N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QTJRTUWSBZMZMT-UHFFFAOYSA-N
29348	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9354	N-(6-Sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144212	-	PUBCHEM	127026695	C10H17N3OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OJQALHBLSWWPHJ-UHFFFAOYSA-N
29349	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9355	3-Phenyl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144210	-	PUBCHEM	127027677	C16H21N3OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZTCVPCNBUBKBA-UHFFFAOYSA-N
29350	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9356	3-(3,4-Dimethoxyphenyl)-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144209	-	PUBCHEM	127027679	C18H25N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KATIKUFCGSOWFA-UHFFFAOYSA-N
29351	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9357	N-(6-Sulfanylhexyl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole-5-carboxamide	BDBM50144208	-	PUBCHEM	127027680	C19H27N3O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HIUNIEQHYXYXSL-UHFFFAOYSA-N
29352	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9358	3-Pyridin-4-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143997	-	PUBCHEM	127027995	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KYZMEJZVXICXQX-UHFFFAOYSA-N
29353	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9359	3-Pyridin-3-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143996	-	PUBCHEM	127025178	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UMHAIDYPJKYSES-UHFFFAOYSA-N
29354	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9360	3-Pyridin-2-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143995	-	PUBCHEM	127028973	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VRGLHLDCWONREK-UHFFFAOYSA-N
29355	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29356	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9361	7-Mercapto-heptanoic acid phenylamide	ZINC13609304|7-MERCAPTO-HEPTANOIC ACID PHENYLAMIDE|N-PHENYL-7-SULFANYLHEPTANAMIDE|THIOL-SAHA (T-SAHA)|BDBM152692	-	PUBCHEM	11379392	C13H19NOS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CFKBMXXDXYFDET-UHFFFAOYSA-N
29357	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ghosh B (2016)	26804233	224813	9362	N'-Hydroxy-N-[(E)-(4-pyridin-3-ylphenyl)methylideneamino]heptanediamide	BRD-K51966546-001-02-2|BDBM50143887	-	PUBCHEM	73707550	C19H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SOSXJHXYTVYMTE-FYJGNVAPSA-N
29358	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ghosh B (2016)	26804233	224813	9363	N'-Hydroxy-N-[(E)-(4-phenylphenyl)methylideneamino]heptanediamide	J3.581.861H|7-OXO-7-[2-[(Z)-(BIPHENYL-4-YL)METHYLENE]HYDRAZINO]HEPTANEHYDROXAMIC ACID|BRD-K35010406-001-01-1|BDBM50143884	-	PUBCHEM	25118059	C20H23N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AEIVDBATQVVQFS-RCCKNPSSSA-N
29359	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Peng FW (2016)	26741358	224814	9364	7-[4-(4-Bromoanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide	BDBM50142796	-	PUBCHEM	127028030	C22H25BrN4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BNWIAUUKBJSRSZ-UHFFFAOYSA-N
29360	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Ndubaku CO (2015)	26713112	224815	9365	BDBM50148921	-	-	CHEMBL	CHEMBL3770443	C25H25ClN6O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBCMHWUFWQFPLV-VVOJOOEHSA-N
29361	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Alverez C (2015)	26713109	224816	9366	1-[3-(5-Nitro-1H-indol-2-yl)phenyl]-N-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]piperidin-4-amine	J3.640.579A|C(C)(C)N1CCN(CC1)CCNC1CCN(CC1)C1=CC(=CC=C1)C=1NC2=CC=C(C=C2C=1)[N+](=O)[O-]|N-[2-(4-ISOPROPYLPIPERAZINO)ETHYL]-1-[3-(5-NITRO-1H-INDOLE-2-YL)PHENYL]PIPERIDINE-4-AMINE|BDBM50158905	-	PUBCHEM	127031857	C28H38N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QOGCSASIXKSUDD-UHFFFAOYSA-N
29362	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9367	2-(1-Methylimidazol-4-yl)-4-(2H-tetrazol-5-yl)pyridine	2-(1-METHYL-1H-IMIDAZOL-4-YL)-4- (2H-TETRAZOL-5-YL)PYRIDINE|2-(1-METHYL-1H-IMIDAZOL-4-YL)-4-(2H-TETRAZOL-5-YL)PYRIDINE|2-(1-METHYLIMIDAZOL-4-YL)-4-(2H-TETRAZOL-5-YL)PYRIDINE|US10273222, EXAMPLE 62|BDBM50158696	-	PUBCHEM	90407594	C10H9N7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JYEUQFOUZAUNTD-UHFFFAOYSA-N
29363	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9368	2-[5-[4-(Cyclopropylmethoxy)phenyl]-1-methylimidazol-4-yl]pyridine-4-carboxylic acid	2-[5-[4-(CYCLOPROPYLMETHOXY)PHENYL]-1-METHYLIMIDAZOL-4-YL]PYRIDINE-4-CARBOXYLIC ACID|BDBM50158695	-	PUBCHEM	90407841	C20H19N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWJQMQXBUJYTHO-UHFFFAOYSA-N
29364	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9369	2-[5-(4-Methoxyphenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acid	2-[5-(4-METHOXYPHENYL)-1-METHYLIMIDAZOL-4-YL]PYRIDINE-4-CARBOXYLIC ACID|NCGC00390841-01|BDBM50158694	-	PUBCHEM	90407809	C17H15N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XGBOARWPNSLLHZ-UHFFFAOYSA-N
29365	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9370	2-(1-Methylimidazol-4-yl)pyridine-4-carboxylic acid	2-(1-METHYLIMIDAZOL-4-YL)PYRIDINE-4-CARBOXYLIC ACID|2-(1-METHYL-1H-IMIDAZOL-4-YL)PYRIDINE-4-CARBOXYLIC ACID|BDBM50158693	-	PUBCHEM	86268882	C10H9N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CZNFQLDDPKKPMX-UHFFFAOYSA-N
29366	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9371	2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic Acid	2-(5-((4-CHLORO-2-METHYLBENZYL)OXY)-1HPYRAZOL-1-YL)ISONICOTINIC ACID (N19)|2-[5-[(4-CHLORO-2-METHYLPHENYL)METHOXY]PYRAZOL-1-YL]PYRIDINE-4-CARBOXYLIC ACID|NCGC00390881-02|6EP|QC-3611|2-{5-[(4-CHLORO-2-METHYLPHENYL)METHOXY]-1H-PYRAZOL-1-YL}PYRIDINE-4-CARBOXYLIC ACID|Q27456366|1613410-75-5|BDBM191600	-	PUBCHEM	74766595	C17H14ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PSOBPHXKKHPWMU-UHFFFAOYSA-N
29367	124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	unknown	target	McAllister TE (2016)	26710088	224817	9372	2-(((2-((2-(Dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid	2-(((2-((2-(DIMETHYLAMINO)ETHYL)(ETHYL)AMINO)-2-OXOETHYL)AMINO)METHYL)ISONICOTINIC ACID (KDM5-C49)|2-[[[2-[2-(DIMETHYLAMINO)ETHYL-ETHYLAMINO]-2-OXOETHYL]AMINO]METHYL]PYRIDINE-4-CARBOXYLIC ACID|2-[({2-[(2-(DIMETHYLAMINO)-ETHYL)(ETHYL)AMINO]-2-OXOETHYL}AMINO)METHYL]ISONICOTINIC ACID|1596348-16-1|6OQJ5L847C|KDM5-C49|UNII-6OQJ5L847C|2-(((2-((2-(DIMETHYLAMINO)ETHYL)(ETHYL)AMINO)-2-OXOETHYL)AMINO)METHYL)ISONICOTINIC ACID|4-PYRIDINECARBOXYLIC ACID, 2-(((2-((2-(DIMETHYLAMINO)ETHYL)ETHYLAMINO)-2-OXOETHYL)AMINO)METHYL)BDBM191598	-	PUBCHEM	86346639	C15H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RGGMVQDDHDCRDM-UHFFFAOYSA-N
29368	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Dixit VA (2016)	26708109	224818	9373	5-{[4-(Benzyloxy)phenyl]methylene}-2,4,6(1H,3H,5H)-pyrimidinetrione	5-{[4-(PHENYLMETHOXY)PHENYL]METHYLENE}-1,3-DIHYDROPYRIMIDINE-2,4,6-TRIONE|242473-63-8|5-[4-(BENZYLOXY)BENZYLIDENE]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE|AKOS000514744|5-{[4-(BENZYLOXY)PHENYL]METHYLENE}-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE|KS-00001T0W|ZINC3139774|5-[(4-PHENYLMETHOXYPHENYL)METHYLIDENE]-1,3-DIAZINANE-2,4,6-TRIONE|ST50170955|MCULE-1677643513|12P-135|STK804651|5-[4-(BENZYLOXY)BENZYLIDENE]BARBITURIC ACID|5-{[4-(BENZYLOXY)PHENYL]METHYLIDENE}-1,3-DIAZINANE-2,4,6-TRIONE|BDBM50137109	-	PUBCHEM	2851123	C18H14N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RPNLKHSBSLHOSQ-UHFFFAOYSA-N
29369	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Dixit VA (2016)	26708109	224818	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29370	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9374	4-[3-(4-Fluorophenyl)-5-(6-sulfanylhexylcarbamoyl)pyrazol-1-yl]butanoic acid	BDBM50143530	-	PUBCHEM	127026737	C20H26FN3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GUKWYUINVSHUKE-UHFFFAOYSA-N
29371	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9375	2-[3-(4-Fluorophenyl)-5-(6-sulfanylhexylcarbamoyl)pyrazol-1-yl]acetic acid	BDBM50143508	-	PUBCHEM	127026735	C18H22FN3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KDSZJUGHUQDOGC-UHFFFAOYSA-N
29372	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9376	(1R,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone	ROMIDEPSIN (FK228, DEPSIPEPTIDE)|ZINC136702520|128517-07-7|BDBM50048864	-	PUBCHEM	11947684	C24H36N4O6S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QSVHVVLASA-N
29373	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29374	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9377	4-[(E)-N-[[4-(Dimethylamino)benzoyl]-methylamino]-C-methylcarbonimidoyl]-N-hydroxybenzamide	BDBM50146080	-	PUBCHEM	127025647	C19H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JCTMSWPCFNKFGT-DEDYPNTBSA-N
29375	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9378	4-[(E)-N-[[4-(Dimethylamino)benzoyl]amino]-C-methylcarbonimidoyl]-N-hydroxybenzamide	BDBM50146079	-	PUBCHEM	122601076	C18H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YBJMRJLHXVKOOB-XDHOZWIPSA-N
29376	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9379	4-[(E)-[[4-(Dimethylamino)benzoyl]-methylhydrazinylidene]methyl]-N-hydroxybenzamide	BDBM50146077	-	PUBCHEM	127025646	C18H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOJNZHSNJLHVML-XDHOZWIPSA-N
29377	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9380	4-[(E)-[[4-(Dimethylamino)benzoyl]hydrazinylidene]methyl]-N-hydroxybenzamide	BDBM50146076	-	PUBCHEM	122601008	C17H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HHDICTUTXIOTBC-WOJGMQOQSA-N
29378	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29379	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9381	4-[(2S)-1-[5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-(2-phenylethyl)benzimidazol-1-yl]propan-2-yl]morpholine	BDBM50151662	-	PUBCHEM	127031779	C27H32N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SAMCWHOXZPKYQG-IBGZPJMESA-N
29380	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9382	[[(3R)-4-[[3-[2-[2-[[(5S)-5-Acetamido-6-amino-6-oxohexyl]amino]-2-oxoethyl]sulfanylethylamino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl hydrogen phosphate	AC-LYS(COA)-NH2|BDBM50255529	-	PUBCHEM	44571034	C31H53N10O19P3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YGZKIOPJGFQDSR-QGSWMBNESA-N
29381	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9383	(2S)-2-[2-[[(1S)-1-Carboxy-3-[5-[(Z)-[(5S)-5-[3-(diaminomethylideneamino)propyl]-3,6-dioxopiperazin-2-ylidene]methyl]-2-hydroxyphenoxy]propyl]amino]-2-oxoethyl]-2-hydroxybutanedioic acid	BDBM50151656	-	PUBCHEM	127033885	C25H32N6O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GRAFKVRBLJRCBH-NCBISDQCSA-N
29382	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9384	(2S)-2-[[(3S)-3-Carboxy-5-[[(1S)-1-carboxy-3-[5-[(Z)-[(5S)-5-[3-(diaminomethylideneamino)propyl]-3,6-dioxopiperazin-2-ylidene]methyl]-2-hydroxyphenoxy]propyl]amino]-3-hydroxy-5-oxopentanoyl]amino]butanedioic acid	NK-13650A|BDBM50151655	-	PUBCHEM	71481176	C29H37N7O15	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CVSHHZDMYAPZPV-DFYJTYCZSA-N
29383	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9385	Tert-butyl N-[5-[[2-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]acetyl]amino]pentyl]carbamate	BDBM50151651	-	PUBCHEM	50899265	C33H58N9O19P3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XQXLJFXFNXYRML-HSJNEKGZSA-N
29384	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kachhadia V (2016)	26689485	224822	9386	(E)-3-[4-[(E)-3-(Cyclopropylamino)-2-(4-fluorophenyl)prop-1-enyl]phenyl]-N-hydroxyprop-2-enamide	BDBM50143215	-	PUBCHEM	25269097	C21H21FN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NODIYCZWVUUEMT-HTZRGULJSA-N
29385	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kachhadia V (2016)	26689485	224822	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29386	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29387	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29388	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29389	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29390	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9387	N-Hydroxy-2-naphthalen-2-yl-1,3-oxazole-4-carboxamide	BDBM50148620	-	PUBCHEM	127027175	C14H10N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SAZKVZYUJRPYFI-UHFFFAOYSA-N
29391	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9388	2-(4-Chlorophenyl)-N-hydroxy-1,3-oxazole-4-carboxamide	BDBM50148617	-	PUBCHEM	127025656	C10H7ClN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KHHYTDYDQPEPGS-UHFFFAOYSA-N
29392	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9389	N-Hydroxy-2-(4-phenylphenyl)-1,3-oxazole-4-carboxamide	BDBM50148613	-	PUBCHEM	127028391	C16H12N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TXHNXBSXQZDEJE-UHFFFAOYSA-N
29393	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9390	2-(4-Bromophenyl)-N-hydroxy-1,3-oxazole-4-carboxamide	N-HYDROXY-2-(4-BROMOPHENYL)OXAZOLE-4-CARBOXAMIDE|P7V|J3.601.433D|2-(4-BROMOPHENYL)-N-HYDROXY-1,3-OXAZOLE-4-CARBOXAMIDE|BDBM50148612	-	PUBCHEM	127027171	C10H7BrN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KHPRTOQUGAUDCM-UHFFFAOYSA-N
29394	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29395	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Thaler F (2016)	26629860	224825	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29396	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Romero FA (2016)	26572217	224826	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29397	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ni M (2015)	26481659	224827	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29398	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Peng FW (2015)	26475519	224828	9392	6-[4-(2,4-Dichloroanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyhexanamide	BDBM50132484	-	PUBCHEM	122195536	C21H22Cl2N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQVSMMXKDYANJJ-UHFFFAOYSA-N
29399	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9393	Ricolinostat	SW219836-1|ZINC89630354|W-5979|AS-73344|D10661|ROCILINOSTAT (ACY-1215)|GTPL7010|ROCILINOSTAT|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]PYRIMIDINE-5-CARBOXAMIDE|ACY-63|DTXSID40157148|RICOLINOSTAT (USAN/INN)|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)-|CCG-269054|AK151416|7-{[2-(DIPHENYLAMINO)PYRIMIDIN-5-YL]FORMAMIDO}-N-HYDROXYHEPTANAMIDE|SMR004702950|EX-A139|UNII-WKT909C62B|ACN-030031|S8001|AH4|CS-0965|DB12376|Q27088553|NS00073045|ACY-1215|1316214-52-4|SB17054|CC-661|HMS3426C09|US8609678, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE [26]|AB0032517|BCP06028|A11940|X5832|AC-30258|2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE|MLS006011181|N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-2-(N-PHENYLANILINO)PYRIMIDINE-5-CARBOXAMIDE|HY-16026|WKT909C62B|NCGC00345802-05|J-690127|ACY1215|AX8288032|AKOS024259260|RICOLINOSTAT (ACY-1215)|RICOLINOSTAT [USAN:INN]|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-5-PYRIMIDINECARBOXAMIDE|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-|NCGC00345802-01|RICOLINOSTAT|HMS3653F17|KS-00000SAV|BDBM50439674	-	PUBCHEM	53340666	C24H27N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGZYDVAGYRLSKP-UHFFFAOYSA-N
29400	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9394	N-Hydroxy-6-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151381	-	PUBCHEM	122550126	C22H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YHQAMQHTTOJBPC-UHFFFAOYSA-N
29401	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9395	N-Hydroxy-5-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]pentanamide	ONC(CCCCOC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151380	-	PUBCHEM	122550235	C21H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VINHTOOQEORVNT-UHFFFAOYSA-N
29402	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9396	N-Hydroxy-2-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]acetamide	ONC(COC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151378	-	PUBCHEM	122550234	C18H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MPMPKDWQOVDGGV-UHFFFAOYSA-N
29403	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9397	N-Hydroxy-6-[2-methoxy-5-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=C(C=CC(=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)OC)=O|BDBM50151377	-	PUBCHEM	122550213	C23H28N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOLDSRJBCFTJIA-UHFFFAOYSA-N
29404	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9398	Hdac6-IN-1	HY-18947|CS-0014660|SKLB-23BB|S8743|N-HYDROXY-4-[2-METHOXY-5-[METHYL(2-METHYLQUINAZOLINE-4-YL)AMINO]PHENOXY]BUTANAMIDE|ONC(CCCOC1=C(C=CC(=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)OC)=O|J3.553.794E|1815580-06-3|HDAC6-IN-1|BDBM50151375	-	PUBCHEM	122550211	C21H24N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FWXZZFONXWYSEF-UHFFFAOYSA-N
29405	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9399	N-Hydroxy-6-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]hexanamide	BDBM50151325	-	PUBCHEM	127031757	C21H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YUAKVYNOFMVTES-UHFFFAOYSA-N
29406	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9400	N-Hydroxy-5-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]pentanamide	BDBM50151324	-	PUBCHEM	127030500	C20H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZRIVRHBHISBBGJ-UHFFFAOYSA-N
29407	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9401	N-Hydroxy-4-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]butanamide	BDBM50150960	-	PUBCHEM	127031734	C19H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMJDOVVCXHTCNO-UHFFFAOYSA-N
29408	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9402	N-Hydroxy-2-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]acetamide	BDBM50150959	-	PUBCHEM	127031756	C17H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZDRSRLVZCRYVJO-UHFFFAOYSA-N
29409	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9403	N-Hydroxy-6-[4-[methyl(quinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150955	-	PUBCHEM	122550135	C21H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NXBDQDGEFPQVSI-UHFFFAOYSA-N
29410	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9404	N-Hydroxy-5-[4-[methyl(quinazolin-4-yl)amino]phenoxy]pentanamide	ONC(CCCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150954	-	PUBCHEM	122550134	C20H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TYGPIYZPTOOAMW-UHFFFAOYSA-N
29411	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9405	N-Hydroxy-4-[4-[methyl(quinazolin-4-yl)amino]phenoxy]butanamide	ONC(CCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150953	-	PUBCHEM	122550129	C19H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGPSFMYVFDFUJS-UHFFFAOYSA-N
29412	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9406	N-Hydroxy-2-[4-[methyl(quinazolin-4-yl)amino]phenoxy]acetamide	ONC(COC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150951	-	PUBCHEM	122550132	C17H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WKPDRDKNRMYFAG-UHFFFAOYSA-N
29413	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
29414	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29415	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Musso L (2015)	26376355	224830	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29416	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	unknown	target	Jain AD (2015)	26363505	224831	9407	(4S)-5-[[(2S)-1-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[2-[[(2S,3R)-2-[[(2S)-4-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-3-carboxy-2-[[(2S)-2-[[2-(3-hydroxy-6-oxoxanthen-9-yl)-5-isothiocyanatobenzoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]butanoyl]amino]butanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-oxopentanoic acid	BDBM50130558	-	PUBCHEM	122194818	C67H79N11O22S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OQIWZBQSWOIZFA-IEZRXWCASA-N
29417	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	unknown	target	Jain AD (2015)	26363505	224831	9408	2,2'-(Naphthalene-1,4-Diylbis(((4-Methoxyphenyl)sulfonyl)azanediyl))diacetamide	2,2'-(NAPHTHALENE-1,4-DIYLBIS{[(4-METHOXYPHENYL)SULFONYL]IMINO})DIACETAMIDE (NON-PREFERRED NAME)|41P|2,2'-(NAPHTHALENE-1,4-DIYLBIS(((4-METHOXYPHENYL)SULFONYL)AZANEDIYL))DIACETAMIDE|Q27454330|BDBM50130549	-	PUBCHEM	91885637	C28H28N4O8S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZUIXHSIMKQZYPV-UHFFFAOYSA-N
29418	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	unknown	target	Jain AD (2015)	26363505	224831	9409	2,2'-(Naphthalene-1,4-diylbis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetic acid	COMPOUND 2 [PMID: 24512214]|CPUY192018|2,2'-(NAPHTHALENE-1,4-DIYLBIS(((4-METHOXYPHENYL)SULFONYL)AZANEDIYL))DIACETIC ACID|2,2'-[1,4-NAPHTHALENEDIYLBIS[(4-METHOXYPHENYLSULFONYL)IMINO]]BISACETIC ACID|BRD-K55096910-001-01-4|COMPOUND 18E [PMID: 26258437]|GTPL9710|1567836-15-0|2-[[4-[CARBOXYMETHYL-(4-METHOXYPHENYL)SULFONYLAMINO]NAPHTHALEN-1-YL]-(4-METHOXYPHENYL)SULFONYLAMINO]ACETIC ACID|BDBM50006932	-	PUBCHEM	73330369	C28H26N2O10S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSIQJUNYMMCTB-UHFFFAOYSA-N
29419	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2015)	26331334	224832	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29420	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Muthyala R (2015)	26264503	224833	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29421	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Muthyala R (2015)	26264503	224833	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29422	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Chessari G (2015)	26218264	224834	9410	1-(6-Benzyl-3,3-dimethyl-2H-pyrrolo[3,2-c]pyridin-1-yl)-2-[(2R,5R)-2-(methoxymethyl)-5-methylpiperazin-1-yl]ethanone	1-(6-BENZYL-3,3-DIMETHYL-2H-PYRROLO[3,2-C]PYRIDIN-1-YL)-2-[(2R,5R)-2-(METHOXYMETHYL)-5-METHYLPIPERAZIN-1-YL]ETHANONE|US9018214, 63|1-(3,3-DIMETHYL-6-BENZYL-2,3-DIHYDRO-1H-PYRROLO[3,2-C]PYRIDINE-1-YL)-2-((3R,6R)-3-METHYL-6-METHOXYMETHYLPIPERAZINE-1-YL)ETHANONE|BDBM156012	-	PUBCHEM	70981017	C25H34N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XOZJVPQFZSCGTE-WIYYLYMNSA-N
29423	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9411	N-[1-(2-Chloro-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-CHLORO-4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109015	-	PUBCHEM	122184850	C24H27ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IJGUAWCQKOESOS-UHFFFAOYSA-N
29424	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9412	N-[1-(2-Bromo-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-BROMO-4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109014	-	PUBCHEM	122184851	C24H27BrN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QNXRAIMDOJFMKD-UHFFFAOYSA-N
29425	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9413	N'-Hydroxy-N-[1-(4-methylanilino)isoquinolin-7-yl]octanediamide	N-[1-[(4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109013	-	PUBCHEM	122184847	C24H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DHMRFGYKNXQOFG-UHFFFAOYSA-N
29426	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9414	N'-Hydroxy-N-[1-(naphthalen-2-ylamino)isoquinolin-7-yl]octanediamide	BDBM50109011	-	PUBCHEM	122184848	C27H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HUKJAHRJEYMMCE-UHFFFAOYSA-N
29427	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9415	N-[1-(4-Bromo-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUORO-4-BROMOPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109010	-	PUBCHEM	122184845	C23H24BrFN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DFKQAHYOXDWTAQ-UHFFFAOYSA-N
29428	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9416	(E)-N-Hydroxy-3-[4-[[[1-(4-methylanilino)isoquinolin-7-yl]amino]methyl]phenyl]prop-2-enamide	BDBM50109009	-	PUBCHEM	122185150	C26H24N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KPLJHTZFLSOICT-MDWZMJQESA-N
29429	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9417	N-[1-(3-Chloro-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUORO-3-CHLOROPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109008	-	PUBCHEM	122184846	C23H24ClFN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LYWPEQFLYUJPIU-UHFFFAOYSA-N
29430	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9418	N'-Hydroxy-N-(1-morpholin-4-ylisoquinolin-7-yl)octanediamide	BDBM50109006	-	PUBCHEM	122184854	C21H28N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DTLWMGPSWXSCIY-UHFFFAOYSA-N
29431	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9419	N'-Hydroxy-N-[1-(4-propan-2-ylpiperazin-1-yl)isoquinolin-7-yl]octanediamide	BDBM50109004	-	PUBCHEM	122184855	C24H35N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KUEFYQRLDVPNAG-UHFFFAOYSA-N
29432	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9420	N-[1-(2-Fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUOROPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109002	-	PUBCHEM	122184852	C23H25FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AGZGHJKLKCIIAU-UHFFFAOYSA-N
29433	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9421	N-[2-[(2,4-Dimethoxyphenyl)methyl]-1-oxoisoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50109000	-	PUBCHEM	122185147	C26H31N3O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GIKBCAFOYUWQMO-UHFFFAOYSA-N
29434	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9422	N-[1-(2-Fluoro-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50108999	-	PUBCHEM	122184849	C24H27FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLJIGRZNVRDVNW-UHFFFAOYSA-N
29435	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9423	N'-Hydroxy-N-[2-(3-methylbutyl)-1-oxoisoquinolin-7-yl]octanediamide	BDBM50108184	-	PUBCHEM	122185146	C22H31N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FSIYMAGFRRSGGY-UHFFFAOYSA-N
29436	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9424	N-[2-[2-(Diethylamino)ethyl]-1-oxoisoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50108162	-	PUBCHEM	122184858	C23H34N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZAKBEXUJXNNGOJ-UHFFFAOYSA-N
29437	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9425	N-(2-Butyl-1-oxoisoquinolin-7-yl)-N'-hydroxyoctanediamide	BDBM50108142	-	PUBCHEM	122184857	C21H29N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CIMZZSMMMYOQJV-UHFFFAOYSA-N
29438	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9426	N'-Hydroxy-N-[1-(3-methoxypropylamino)isoquinolin-7-yl]octanediamide	BDBM50108129	-	PUBCHEM	122184856	C21H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGLLPZGTTQFMEG-UHFFFAOYSA-N
29439	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29440	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Smith CR (2015)	26087137	224836	9427	4-Amino-8-(5-Methyl-1h-Indazol-6-Yl)cinnoline-3-Carboxamide	4-AMINO-8-(5-METHYL-1H-INDAZOL-6-YL)CINNOLINE-3-CARBOXAMIDE|4-AMINO-8-(5-METHYL-1H-INDAZOLE-6-YL)CINNOLINE-3-CARBOXAMIDE|4L6|Q27454796|BDBM50097393	-	PUBCHEM	71765510	C17H14N6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PTHVKCSYXICMAR-UHFFFAOYSA-N
29441	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29442	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29443	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29444	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9428	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3-thia-7,14,17,21-tetrazatricyclo[14.3.1.12,5]henicosa-1(20),2(21),16,18-tetraene-6,9,13-trione	BDBM50098420	-	PUBCHEM	122181882	C23H30N4O4S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YSQNJKVHVWRCPW-FXHDEUNJSA-N
29445	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9429	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3-thia-7,14,20,21-tetrazatricyclo[14.3.1.12,5]henicosa-1(19),2(21),16(20),17-tetraene-6,9,13-trione	(4R)-4,2-[CARBONYLIMINO[(S)-2-OXO-1-ISOPROPYLETHYLENE]OXY[(S)-1-OXO-7-MERCAPTO-4-HEPTENE-3,1-DIYL]IMINOMETHYLENE(PYRIDINE-2,6-DIYL)]-4BETA-METHYL-4,5-DIHYDROTHIAZOLE|BDBM50098418	-	PUBCHEM	25257993	C23H30N4O4S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	USYOVMNNRIHXJQ-BEIBECRVSA-N
29446	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9430	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione	(4R)-4,2'-[CARBONYLIMINO[(S)-1-OXO-3-METHYLBUTANE-2,1-DIYL]OXY[(S)-1-OXO-7-MERCAPTO-4-HEPTENE-3,1-DIYL]IMINOMETHYLENE]-4BETA-METHYL-4,5-DIHYDRO-2,4'-BITHIAZOLE|(2S,5S,17R)-2-ISOPROPYL-5-[(E)-4-MERCAPTO-1-BUTENYL]-17-METHYL-13,10:17,14-DIEPINITRILO-4-OXA-11,15-DITHIA-1,8-DIAZACYCLOOCTADECA-12-ENE-3,7,18-TRIONE|BDBM50098414	-	PUBCHEM	24938735	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-BNVDZZMOSA-N
29447	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Yadav RR (2015)	26048785	224839	9431	5-(4-Pyridin-3-ylthiophen-2-yl)-1,3-thiazole	BDBM50105913	-	PUBCHEM	122184057	C12H8N2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WNKQZLFWZLQFOH-UHFFFAOYSA-N
29448	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	9432	Naphthalen-1-yl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate	BDBM50094760	-	PUBCHEM	122181047	C36H36N2O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PQXAOJPTBDMVNK-UHFFFAOYSA-N
29449	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	9433	8-[4-[6-(3-Hydroxyphenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid	BDBM50094750	-	PUBCHEM	122180823	C32H33NO9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNLHZLHXGMYVNW-UHFFFAOYSA-N
29450	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29451	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Du G (2015)	25978962	224841	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29452	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Daniel KB (2015)	25974739	224842	9434	N-Phenyl-N'-[(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methoxy]octanediamide	BDBM50089657	-	PUBCHEM	122177622	C24H30N2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HXFDEOSGMWWMSA-UHFFFAOYSA-N
29453	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Daniel KB (2015)	25974739	224842	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29454	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	unknown	target	Henry JR (2015)	25965804	224843	9435	LY-3009120	AS-74984|LY 3009120|GTPL8943|1GDT36RARO|UNII-1GDT36RARO|KS-00001CZH|3-(3,3-DIMETHYLBUTYL)-1-{2-FLUORO-4-METHYL-5-[7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL]PHENYL}UREA|J3.580.324F|AC-30240|LY-3009120|S7842|1454682-72-4|DP 4978|NCGC00481604-01|UREA, N-(3,3-DIMETHYLBUTYL)-N'-[2-FLUORO-4-METHYL-5-[7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL]PHENYL]-|UREA, N-(3,3-DIMETHYLBUTYL)-N'-(2-FLUORO-4-METHYL-5-(7-METHYL-2-(METHYLAMINO)PYRIDO(2,3-D)PYRIMIDIN-6-YL)PHENYL)-|1-(3,3-DIMETHYLBUTYL)-3-[2-FLUORO-4-METHYL-5-[7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL]PHENYL]UREA|SB16924|DP-4978|4Z5|1-(3,3-DIMETHYLBUTYL)-3-(2-FLUORO-4-METHYL-5-(7-METHYL-2-(METHYLAMINO)PYRIDO(2,3-D)PYRIMIDIN-6-YL)PHENYL)UREA|LY3009120|QC-11801|AK173776|BCP23869|1-(3,3-DIMETHYLBUTYL)-3-{2-FLUORO-4-METHYL-5-[7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL]PHENYL}UREA|N-(3,3-DIMETHYLBUTYL)-N'-[2-FLUORO-4-METHYL-5-[7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL]PHENYL]UREA|EX-A1638|ZINC205861291|1-(2-FLUORO-4-METHYL-5-(2-METHYLAMINO-7-METHYLPYRIDO[2,3-D]PYRIMIDINE-6-YL)PHENYL)-3-(3,3-DIMETHYLBUTYL)UREA|DP-4978;LY-3009120|Q27082823|HY-12558|CCG-268937|1-(3,3-DIMETHYLBUTYL)-3-(2-FLUORO-4-METHYL-5-(7-METHYL-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-6-YL)PHENYL)UREA|BDBM50096279	-	PUBCHEM	71721540	C23H29FN6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HHCBMISMPSAZBF-UHFFFAOYSA-N
29455	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Duan W (2015)	25906087	224844	9436	6-[[4-(Benzenesulfonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]oxy]-N-hydroxyhexanamide	BDBM50087853	-	PUBCHEM	118737455	C14H17N3O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AGDGTFUFKSHWRN-UHFFFAOYSA-N
29456	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Duan W (2015)	25906087	224844	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29457	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Di Pompo G (2015)	25905694	224845	9437	N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamide	MC1742|MC 1742|5-{[4-(BIPHENYL-4-YL)-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL]SULFANYL}-N-HYDROXYPENTANAMIDE|ZINC140782936|5-[[6-OXO-4-(4-PHENYLPHENYL)-1H-PYRIMIDIN-2-YL]SULFANYL]PENTANEHYDROXAMIC ACID|AKOS027470271|1776116-74-5|BDBM50087845	-	PUBCHEM	136173089	C21H21N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AOFVDNFTELWRHV-UHFFFAOYSA-N
29458	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Di Pompo G (2015)	25905694	224845	9438	N-[6-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]pyridin-3-yl]-2,3-diphenylpropanamide	J3.561.771J|MC-2625|BDBM50087841	-	PUBCHEM	118737400	C23H21N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UQSIPNLHOWORHA-BUHFOSPRSA-N
29459	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9439	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[6-(hydroxyamino)-6-oxohexyl]benzamide	BDBM50080071	-	PUBCHEM	136961657	C20H24N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LAPSXONRKCNPMH-UHFFFAOYSA-N
29460	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9440	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-hydroxybenzamide	BDBM50080008	-	PUBCHEM	136961654	C14H13N7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DUXRBKWTYAMJCH-UHFFFAOYSA-N
29461	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9441	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	BDBM50080007	-	PUBCHEM	136961658	C21H26N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FDKBZGYHEWRDAU-UHFFFAOYSA-N
29462	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9442	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[8-(hydroxyamino)-8-oxooctyl]benzamide	BDBM50080006	-	PUBCHEM	136961659	C22H28N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UMZXWCBRVCVILS-UHFFFAOYSA-N
29463	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9443	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[9-(hydroxyamino)-9-oxononyl]benzamide	BDBM50080005	-	PUBCHEM	136961660	C23H30N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QJGGEUHIPSSJGP-UHFFFAOYSA-N
29464	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	He S (2015)	25815139	224847	9444	N-Hydroxy-7-[3-[4-[[(7-hydroxy-21-methyl-14-oxo-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15(20),16,18-heptaen-17-yl)amino]methyl]phenyl]-1,2,4-oxadiazol-5-yl]heptanamide	BDBM50089085	-	PUBCHEM	122177957	C35H37N7O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FTVNKVXRXIRGTC-UHFFFAOYSA-N
29465	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	He S (2015)	25815139	224847	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29466	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9445	4-Methoxy-N-(2-methyl-2-phenylpropyl)-1,2-benzothiazol-3-amine	4-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)-1,2-BENZOTHIAZOL-3-AMINE|BDBM50120918	-	PUBCHEM	16050950	C18H20N2OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NKBXMDAHDCPWMN-UHFFFAOYSA-N
29467	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9446	4-Methoxy-3-[(2-methyl-2-phenylpropyl)amino]-1H-isoindol-1-one	CTK3F7042|929022-79-7|4-METHOXY-3-[(2-METHYL-2-PHENYLPROPYL)AMINO]-1H-ISOINDOL-1-ONE|DTXSID90581575|4-METHOXY-3-[(2-METHYL-2-PHENYLPROPYL)AMINO]ISOINDOL-1-ONE|1H-ISOINDOL-1-ONE, 4-METHOXY-3-[(2-METHYL-2-PHENYLPROPYL)AMINO]BDBM50120917	-	PUBCHEM	135402003	C19H20N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WVNWIKASGFTXTN-UHFFFAOYSA-N
29468	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9447	BDBM50120916	-	-	CHEMBL	CHEMBL3623052	C25H34N4O5S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LCBXDZXDQBCBKU-WBANQOEISA-N
29469	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9448	BDBM50120914	-	-	CHEMBL	CHEMBL3622362	C23H29N3O5S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CJQQFOJFFTZBPF-RXAXNXDRSA-N
29470	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9449	BDBM50120913	-	-	CHEMBL	CHEMBL3622361	C24H26F3N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWGJTTLXQUOTQV-QBNMFFNISA-N
29471	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9450	BDBM50120912	-	-	CHEMBL	CHEMBL3622351	C27H29N5O5S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SLEKHKOESUNGDP-GEQDBVPJSA-N
29472	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9451	BDBM50120911	-	-	CHEMBL	CHEMBL3622350	C25H28F3N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IIYZDGPAUKPRTM-XZMJRDFISA-N
29473	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9452	BDBM50120909	-	-	CHEMBL	CHEMBL3622348	C24H29N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FZCOOJYUTWQXHI-XZMJRDFISA-N
29474	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9453	BDBM50120908	-	-	CHEMBL	CHEMBL3623054	C22H24N6O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YRYVRDWTFZNPGZ-VVOJOOEHSA-N
29475	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9454	BDBM50120907	-	-	CHEMBL	CHEMBL3623053	C25H27N5O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HPNMBDREXVAELJ-FEHRVWHQSA-N
29476	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9455	BDBM50120904	-	-	CHEMBL	CHEMBL3622346	C21H24N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BIALXFMHWCNRAQ-OQIWPSSASA-N
29477	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9456	BDBM50120903	-	-	CHEMBL	CHEMBL3622360	C25H31N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QWHKGOUNYNQXJA-FEHRVWHQSA-N
29478	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9457	BDBM50120901	-	-	CHEMBL	CHEMBL3622358	C24H29N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WFCSBBBTESOXNH-XZMJRDFISA-N
29479	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9458	BDBM50120899	-	-	CHEMBL	CHEMBL3622355	C30H34N4O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KUEIYBKAAMYFKI-IQBDUEADSA-N
29480	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2015)	25801931	224848	9459	4-Methoxy-N-(2-methyl-2-phenylpropyl)-1,2-benzoxazol-3-amine	4-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)-1,2-BENZOXAZOL-3-AMINE|BDBM50022110	-	PUBCHEM	16050462	C18H20N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FRLKYVJLDPLCNR-UHFFFAOYSA-N
29481	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9460	4-[[(3S)-1-(4-Chlorophenyl)-3-methyl-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	J3.522.188C|4-[[(3S)-1-(4-CHLOROPHENYL)-2-OXO-3-METHYLPYRROLIDINE-3-YL]AMINO]BENZHYDROXIMIC ACID|BDBM50078748	-	PUBCHEM	118733374	C18H18ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMBODOHYRWZQEW-SFHVURJKSA-N
29482	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9461	N-Hydroxy-4-[(3-methyl-2-oxo-1-quinolin-6-ylpyrrolidin-3-yl)amino]benzamide	N-HYDROXY-4-[(3-METHYL-2-OXO-1-QUINOLIN-6-YLPYRROLIDIN-3-YL)AMINO]BENZAMIDE|BDBM50078747	-	PUBCHEM	57524107	C21H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RSKIXUXUCRJFFV-UHFFFAOYSA-N
29483	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9462	4-[[1-(4-Chlorophenyl)-3-methyl-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(4-CHLOROPHENYL)-3-METHYL-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|1390618-15-1|BDBM50078695	-	PUBCHEM	57524021	C18H18ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMBODOHYRWZQEW-UHFFFAOYSA-N
29484	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9463	4-[[1-(4-Cyanophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(4-CYANOPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078690	-	PUBCHEM	57524835	C18H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOFSZHJBQOKORL-UHFFFAOYSA-N
29485	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9464	4-[[1-(3,4-Dichlorophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(3,4-DICHLOROPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078687	-	PUBCHEM	57524908	C17H15Cl2N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BVYKJJVMJBRGCE-UHFFFAOYSA-N
29486	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9465	4-[[1-(3-Chlorophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(3-CHLOROPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078680	-	PUBCHEM	57524666	C17H16ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TZTDSVDQFPJDKR-UHFFFAOYSA-N
29487	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9466	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	(R)-7BETA-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-2-CARBOHYDROXIMIC ACID|BDBM50027662	-	PUBCHEM	92045024	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-QGZVFWFLSA-N
29488	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29489	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9467	N-Hydroxy-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-1,2,3,4-tetrahydroquinoline-6-carboxamide	US8716285, 53|BDBM120996	-	PUBCHEM	56933019	C19H18N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YWYZSTJJOZEEKF-UHFFFAOYSA-N
29490	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Falke H (2015)	25730262	224850	9468	10-Bromo-11H-indolo[3,2-c]quinoline-6-carboxylic acid	BDBM50097868	-	PUBCHEM	122181014	C16H9BrN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PCUWPDUAQBAWHT-UHFFFAOYSA-N
29491	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Falke H (2015)	25730262	224850	9469	10-Chloro-11H-indolo[3,2-c]quinoline-6-carboxylic acid	BDBM50097867	-	PUBCHEM	122181013	C16H9ClN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ABRIIMZXUFHPCH-UHFFFAOYSA-N
29492	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Falke H (2015)	25730262	224850	9470	10-Chloro-2-(3-methoxyphenyl)-11H-indolo[3,2-c]quinoline-6-carboxylic acid	BDBM50097863	-	PUBCHEM	122181024	C23H15ClN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VCFPJHJKTXRDGD-UHFFFAOYSA-N
29493	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Falke H (2015)	25730262	224850	9471	10-Bromo-3-methoxy-11H-indolo[3,2-c]quinoline-6-carboxylic acid	BDBM50097855	-	PUBCHEM	122181018	C17H11BrN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ARYGGCNDASPYNG-UHFFFAOYSA-N
29494	114023	8445	-	DYRK2	-	9606	Homo sapiens	unknown	target	Falke H (2015)	25730262	224850	9472	10-Chloro-3-methoxy-11H-indolo[3,2-c]quinoline-6-carboxylic acid	BDBM50097854	-	PUBCHEM	122181017	C17H11ClN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WXMYTQDKBPDSSR-UHFFFAOYSA-N
29495	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Milite C (2015)	25730130	224851	9473	1,3,5-Tribenzylpyrimidine-2,4,6(1H,3H,5H)-trione	1,3,5-TRIBENZYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE|ZINC1701219|CTK7H0853|NSC109117|NSC-109117|BDBM50081172	-	PUBCHEM	268735	C25H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SFFBIIMMBIRGKT-UHFFFAOYSA-N
29496	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Milite C (2015)	25730130	224851	9474	5-Benzoyl-1,3-dibenzyl-1,3-diazinane-2,4,6-trione	BDBM50081171	-	PUBCHEM	118735269	C25H20N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ILBMLQVDTUJJKC-UHFFFAOYSA-N
29497	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9475	(3R,4S)-4-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-[4-(trifluoromethyl)pyrimidin-2-yl]pyrrolidine-3-carboxylic acid	BDBM50377302	-	PUBCHEM	10347566	C29H27F3N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ABIFPJDABNXEMK-GGAORHGYSA-N
29498	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9476	(3R,4S)-4-[[3-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-[4-(trifluoromethyl)pyrimidin-2-yl]pyrrolidine-3-carboxylic acid	BDBM50063315	-	PUBCHEM	58977541	C29H27F3N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CIUUZBXRQNCUIL-GGAORHGYSA-N
29499	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9477	(3R,4S)-4-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-[4-(trifluoromethyl)-1,3-oxazol-2-yl]pyrrolidine-3-carboxylic acid	BDBM50063313	-	PUBCHEM	58977463	C28H26F3N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMYUDUHXSWKCSZ-IRLDBZIGSA-N
29500	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9478	(3R,4S)-4-[[3-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-phenylpyrrolidine-3-carboxylic acid	BDBM50063311	-	PUBCHEM	58977846	C30H30N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WWXVNRULVDGHSD-SQHAQQRYSA-N
29501	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9479	(3R,4S)-4-[2-[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]ethyl]-1-phenoxycarbonylpyrrolidine-3-carboxylic acid	BDBM50063099	-	PUBCHEM	10370056	C32H32N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JHPSLFHGWGTITM-NAKRPHOHSA-N
29502	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Zhang H (2015)	25686852	224852	9480	(3R,4S)-4-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1-phenoxycarbonylpyrrolidine-3-carboxylic acid	BDBM50063089	-	PUBCHEM	10346786	C31H30N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IAXWLNXPJOTFTP-SQHAQQRYSA-N
29503	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9481	Birinapant	AS-17035|DB11782|D10417|SMR004702997|AKOS030526366|ZINC96941868|BIRINAPANT [USAN:INN]|TL-32711|TL32711|UNII-6O4Z07B57R|Q27075298|Z-3165|TL 32711|A12738|BIRINAPANT (USAN/INN)|(2S,2'S)-N,N'-[(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS{METHANEDIYL[(2R,4S)-4-HYDROXYPYRROLIDINE-2,1-DIYL][(2S)-1-OXOBUTANE-1,2-DIYL]}]BIS[2-(METHYLAMINO)PROPANAMIDE] (NON-PREFERRED NAME)|S7015|C42H56F2N8O6|ABP001107|(2S,2'S)-N,N'-((2S,2'S)-((3S,3'S,5R,5'R)-5,5'-((6,6'-DIFLUORO-1H,1'H-[2,2'-BIINDOLE]-3,3'-DIYL)BIS(METHYLENE))BIS(3-HYDROXYPYRROLIDINE-5,1-DIYL))BIS(1-OXOBUTANE-2,1-DIYL))BIS(2-(METHYLAMINO)PROPANAMIDE)|(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-FLUORO-2-[6-FLUORO-3-[[(2R,4S)-4-HYDROXY-1-[(2S)-2-[[(2S)-2-(METHYLAMINO)PROPANOYL]AMINO]BUTANOYL]PYRROLIDIN-2-YL]METHYL]-1H-INDOL-2-YL]-1H-INDOL-3-YL]METHYL]-4-HYDROXYPYRROLIDIN-1-YL]-1-OXOBUTAN-2-YL]-2-(METHYLAMINO)PROPANAM|HY-16591|CS-1719|2269AH|CCG-270498|(2S,2'S)-N,N'-[(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS{METHANEDIYL[(2R,4S)-4-HYDROXYPYRROLIDINE-2,1-DIYL][(2S)-1-OXOBUTANE-1,2-DIYL]}]BIS[2-(METHYLAMINO)PROPANAMIDE]|(2S,2'S)-N,N'-((2S,2'S)-1,1'-((3S,3'S,5R,5'R)-5,5'-(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS(METHYLENE)BIS(3-HYDROXYPYRROLIDINE-5,1-DIYL))BIS(1-OXOBUTANE-2,1-DIYL))BIS(2-(METHYLAMINO)PROPANAMIDE)|BIRINAPANT|EX-A258|SW220103-1|(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-FLUORO-2-[6-FLUORO-3-[[(2R,4S)-4-HYDROXY-1-[(2S)-2-[[(2S)-2-(METHYLAMINO)PROPANOYL]AMINO]BUTANOYL]PYRROLIDIN-2-YL]METHYL]-1H-INDOL-2-YL]-1H-INDOL-3-YL]METHYL]-4-HYDROXYPYRROLIDIN-1-YL]-1-OXOBUTAN-2-YL]-2-(METHYLAMINO)PROPANAMIDE|GTPL7432|PROPANAMIDE, N,N'-[(6,6'-DIFLUORO[2,2'-BI-1H-INDOLE]-3,3'-DIYL)BIS[METHYLENE[(2R,4S)-4-HYDROXY-2,1-PYRROLIDINEDIYL][(1S)-1-ETHYL-2-OXO-2,1-ETHANEDIYL]]]BIS[2-(METHYLAMINO)-, (2S,2'S)-|6O4Z07B57R|BIRINAPANT (TL32711)|DTXSID30155057|GT6|AOB87396|SC-93462|MLS006011237|SB16522|1260251-31-7|BDBM50071920	-	PUBCHEM	49836020	C42H56F2N8O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PKWRMUKBEYJEIX-DXXQBUJASA-N
29504	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9482	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoylamino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071863	-	PUBCHEM	73506880	C56H78N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HEUQZEJFJZTMAR-JSNDJGPMSA-N
29505	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9483	N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N'-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-2,2,3,3,4,4-hexafluoropentanediamide	BDBM50071851	-	PUBCHEM	90089551	C60H78F6N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QPEYDHPWFLBNLA-JSNDJGPMSA-N
29506	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9484	N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]pentanediamide	BDBM50071850	-	PUBCHEM	118497874	C60H84N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NQARVPNPYPHNOD-MLOMWMBNSA-N
29507	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9485	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[4-[2-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]ethyl]benzoyl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071849	-	PUBCHEM	118732584	C64H86N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AWMDVTVHSSNVGB-KHFWCYFCSA-N
29508	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9486	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[(3R,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-7-((3R,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|BDBM50071848	-	PUBCHEM	72704974	C55H76N8O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MCUCXLXZRLIPIS-JSNDJGPMSA-N
29509	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9487	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]oxy-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071847	-	PUBCHEM	72704975	C55H76N8O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IBUAVNGTMFWXEN-JSNDJGPMSA-N
29510	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9488	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-7-(((3S,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)AMINO)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|J3.503.491I|(3S)-2-(N-METHYL-L-ALA-3-METHYL-L-VAL-)-7-[[(2S,4S)-1-(N-METHYL-L-ALA-3-METHYL-L-VAL-)-2-[[(R)-TETRALIN-1-YL]CARBAMOYL]-4-PYRROLIDINYL]AMINO]-N-[(R)-TETRALIN-1-YL]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|BDBM50071846	-	PUBCHEM	117710478	C55H77N9O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WBLPGUTUYUQRAH-JSNDJGPMSA-N
29511	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9489	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N7-((3S,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)-N3-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3,7-DICARBOXAMIDE|BDBM50071845	-	PUBCHEM	72705162	C56H77N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UROIIFBMEHPIGR-JSNDJGPMSA-N
29512	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9490	(2S,4S)-1-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-4-N-[(3S)-2-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-2-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2,4-dicarboxamide	BDBM50071844	-	PUBCHEM	72705161	C56H77N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LVSCGNZQGKTFCG-NVLPYBLVSA-N
29513	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9491	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[2-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]-2-oxoethyl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071843	-	PUBCHEM	73507094	C57H80N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GPKBDHHTTCGIAO-QLYDQGARSA-N
29514	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9492	N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]oxamide	BDBM50071821	-	PUBCHEM	73505798	C57H78N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NZLKULFMTUXYTR-JSNDJGPMSA-N
29515	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9493	1-N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]cyclobutane-1,1-dicarboxamide	BDBM50071820	-	PUBCHEM	73505797	C61H84N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OMVBPXMCVLZSMI-PRXWBPHPSA-N
29516	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9234	4-N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030280	-	PUBCHEM	73506219	C63H82N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAKVXIUNQHYAPX-UPKUDDMJSA-N
29517	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9494	(2S)-N'-Hydroxy-2-[[(2S)-4-oxoazetidine-2-carbonyl]amino]-N-phenyloctanediamide	BDBM50042849	-	PUBCHEM	72947043	C18H24N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GHCWLYKERZOPPW-KBPBESRZSA-N
29518	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9495	(2S)-N'-Hydroxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-N-phenyloctanediamide	ST8086AA1|(2S)-N-[(1S)-7-(HYDROXYAMINO)-7-OXO-1-(PHENYLCARBAMOYL)HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|BDBM50042848	-	PUBCHEM	72946833	C19H26N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QMGDCUHFYVMSBA-GJZGRUSLSA-N
29519	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9496	(2S)-N'-Hydroxy-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]-N-[3-(trifluoromethyl)phenyl]octanediamide	ST-8078-AA1|(2R)-N-[(1S)-7-(HYDROXYAMINO)-7-OXO-1-[[3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL]HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|ST8078AA1|SB19290|1528755-83-0|BDBM50042847	-	PUBCHEM	72710871	C20H25F3N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XVGBJXUAVWXLJX-LSDHHAIUSA-N
29520	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9497	(2S)-N'-Hydroxy-N-(3-methylphenyl)-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]octanediamide	(2R)-N-[(1S)-7-(HYDROXYAMINO)-1-(M-TOLYLCARBAMOYL)-7-OXO-HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|ST8074AA1|BDBM50042846	-	PUBCHEM	72947044	C20H28N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DAGWCJGDWGPDPA-JKSUJKDBSA-N
29521	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9498	(2R)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamide	BDBM50042845	-	PUBCHEM	91884636	C18H25N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YYSCXBPFYMVUDP-LSDHHAIUSA-N
29522	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9499	(2R)-5-Oxo-N-[(2S)-1-oxo-7-sulfanyl-1-[3-(trifluoromethyl)anilino]heptan-2-yl]pyrrolidine-2-carboxamide	BDBM50027520	-	PUBCHEM	118719817	C19H24F3N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CXRLQBYGPWEWJP-LSDHHAIUSA-N
29523	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29524	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9500	BDBM50040557	-	-	CHEMBL	CHEMBL3361178	C24H25N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RFOKLKNGIPKNDF-JCNLHEQBSA-N
29525	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9501	BDBM50040551	-	-	CHEMBL	CHEMBL3361184	C25H28N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVMHVBWGXWQOLU-XUTJKUGGSA-N
29526	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9502	BDBM50040550	-	-	CHEMBL	CHEMBL3361185	C24H26N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FPPFUGYLWPKNTA-UAPYVXQJSA-N
29527	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9503	BDBM50040513	-	-	CHEMBL	CHEMBL3361210	C25H28FN5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VLNGECBZQIDCNU-WGSAOQKQSA-N
29528	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9504	BDBM50040512	-	-	CHEMBL	CHEMBL3361211	C27H31N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMCROPORCNMTHB-MEMLXQNLSA-N
29529	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9505	BDBM50040506	-	-	CHEMBL	CHEMBL3361216	C27H32N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QYDMQKBOHABCOZ-AQYVVDRMSA-N
29530	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9506	BDBM50040505	-	-	CHEMBL	CHEMBL3361217	C26H31N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IAHVLWVJZMFEPN-XYWHTSSQSA-N
29531	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9507	BDBM50040499	-	-	CHEMBL	CHEMBL3361223	C27H29N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMBRNCPCPMAUCV-MXVIHJGJSA-N
29532	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9508	BDBM50040498	-	-	CHEMBL	CHEMBL3361224	C26H29N7O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XBDONALUAKOWDJ-WGSAOQKQSA-N
29533	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9509	BDBM50040497	-	-	CHEMBL	CHEMBL3361225	C27H29N5OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PUERLUHEKCOMSQ-MXVIHJGJSA-N
29534	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9510	BDBM50040496	-	-	CHEMBL	CHEMBL3361226	C27H30N6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LJIJDHSXMUSZQW-MXVIHJGJSA-N
29535	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	9511	N-[(2S)-1-[3-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]phenoxy]-3-(1H-indol-3-yl)propan-2-yl]-4-methoxybenzamide	BDBM50038747	-	PUBCHEM	118720522	C28H27N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UXMMCAXDMKCFRK-UNJYKCMZSA-N
29536	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	9512	N-[(2S)-1-[3-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]phenoxy]-3-(1H-indol-3-yl)propan-2-yl]-2-methoxybenzamide	BDBM50038729	-	PUBCHEM	118720529	C28H27N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VSRRZSNVPQPAFD-ARKBFRDHSA-N
29537	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29538	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Zwick V (2014)	25455492	224856	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29539	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9513	N-[[4-(Hydroxycarbamoyl)phenyl]methyl]-1-methylpyrrole-2-carboxamide	1454308-22-5|DB-096476|BDBM50440912	-	PUBCHEM	73333311	C14H15N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FOBBYTXDJVRRLB-UHFFFAOYSA-N
29540	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9514	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide	ZINC68248700|N-HYDROXY-2-(1-METHYLPYRROLE-2-CARBONYL)-3,4-DIHYDRO-1H-ISOQUINOLINE-6-CARBOXAMIDE|EX-A1852|BCP29593|SYN1218|CS-0064770|N-HYDROXY-2-(1-METHYL-1H-PYRROLE-2-CARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBOXAMIDE|MPI 5A;MPI5A;HDAC6 INHIBITOR;HISTONE DEACETYLASE 6|1259296-46-2|MPI_5A|MPI-5A|DB-092801|HY-113957|1,2,3,4-TETRAHYDRO-N-HYDROXY-2-[(1-METHYL-1H-PYRROL-2-YL)CARBONYL]-6-ISOQUINOLINECARBOXAMIDE|BDBM50440907	-	PUBCHEM	49831258	C16H17N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NNQAQGDSGCGFER-UHFFFAOYSA-N
29541	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29542	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9515	N-Hydroxy-7-(4-phenylbenzoyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide	N-HYDROXY-7-(4-PHENYLBENZOYL)-6,8-DIHYDRO-5H-IMIDAZO[1,2-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036305	-	PUBCHEM	53390842	C20H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OGQGBQMGXFYPBR-UHFFFAOYSA-N
29543	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9516	7-(1-Benzothiophene-2-carbonyl)-N-hydroxy-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide	7-(1-BENZOTHIOPHENE-2-CARBONYL)-N-HYDROXY-6,8-DIHYDRO-5H-IMIDAZO[1,2-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036304	-	PUBCHEM	58465842	C16H14N4O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GBJSJGWUCWJYTR-UHFFFAOYSA-N
29544	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9517	2-(4,5-Dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	2-(4,5-DICHLORO-1-METHYLPYRROLE-2-CARBONYL)-N-HYDROXY-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036303	-	PUBCHEM	58465719	C14H14Cl2N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GPVDZHZKWSWTAW-UHFFFAOYSA-N
29545	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9518	2-(1-Benzothiophene-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	BDBM50036301	-	PUBCHEM	118719410	C17H15N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PKOFMNJPOQAOMK-UHFFFAOYSA-N
29546	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9519	N-Hydroxy-2-(4-methoxybenzoyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(4-METHOXYBENZOYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036300	-	PUBCHEM	87400677	C16H17N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBYDKMSHGGWYID-UHFFFAOYSA-N
29547	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9520	2-(Cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	2-(CYCLOHEXANECARBONYL)-N-HYDROXY-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036299	-	PUBCHEM	58465664	C15H21N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IRYNPILZVVOIKV-UHFFFAOYSA-N
29548	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9521	N-Hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(1-METHYLINDOLE-5-CARBONYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036296	-	PUBCHEM	58465755	C18H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZVYGMGIDIFWWGW-UHFFFAOYSA-N
29549	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9522	N-Hydroxy-2-(4-phenylbenzoyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(4-PHENYLBENZOYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036295	-	PUBCHEM	58465681	C21H19N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSAEIUYNAKOEW-UHFFFAOYSA-N
29550	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9523	N-Hydroxy-5-(1-methylindole-2-carbonyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide	N-HYDROXY-5-(1-METHYLINDOLE-2-CARBONYL)-6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036291	-	PUBCHEM	58465705	C17H17N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ODOAGJBJOFXVAD-UHFFFAOYSA-N
29551	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9524	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(1-METHYLPYRROLE-2-CARBONYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036285	-	PUBCHEM	58465708	C14H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HXYDFXUSMZJLIU-UHFFFAOYSA-N
29552	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9525	Tubacin	AC-28328|DIOX-H_003551|Q27089032|AC1O7Y2P|TUBACIN (BML-GR362)|CTK8E6516|S2239|A10954|EX-A2172|1350555-93-9|HY-13428|CCG-270408|ZINC27551136|TUBACIN, >=98% (HPLC)|GTPL7374|537049-40-4|NCGC00346840-01|SW219084-1|BRD-K98426715-001-01-9|Y6280|N1-(4-((2R,4R,6S)-4-(((4,5-DIPHENYLOXAZOL-2-YL)THIO)METHYL)-6-(4-(HYDROXYMETHYL)PHENYL)-1,3-DIOXAN-2-YL)PHENYL)-N8-HYDROXYOCTANEDIAMIDE|N-[4-[(2R,4R,6S)-4-[[(4,5-DIPHENYL-2-OXAZOLYL)THIO]METHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|C41H43N3O7S|OCTANEDIAMIDE, N1-(4-((2R,4R,6S)-4-(((4,5-DIPHENYL-2-OXAZOLYL)THIO)METHYL)-6-(4-(HYDROXYMETHYL)PHENYL)-1,3-DIOXAN-2-YL)PHENYL)-N8-HYDROXY-, REL-|UNII-02C2G1D30D COMPONENT BHUZLJOUHMBZQY-YXQOSMAKSA-N|NCGC00346840-03|CS-5738|N-[4-[(2R,4R,6S)-4-[[4,5-DI(PHENYL)-1,3-OXAZOL-2-YL]SULFANYLMETHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|N-[4-[(2R,4R,6S)-4-[(4,5-DIPHENYL-1,3-OXAZOL-2-YL)SULFANYLMETHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|N-(4-{(2R,4R,6S)-4-{[(4,5-DIPHENYL-1,3-OXAZOL-2-YL)SULFANYL]METHYL}-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL}PHENYL)-N -HYDROXYOCTANEDIAMIDE|AKOS024457607|TUBACIN|KS-0000185J|BDBM22449	-	PUBCHEM	6675804	C41H43N3O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BHUZLJOUHMBZQY-YXQOSMAKSA-N
29553	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29554	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9526	N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamide	2-[5-(3-NITROPHENYL)FURFURYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-7-CARBOHYDROXIMIC ACID|BDBM50027664	-	PUBCHEM	101882265	C21H19N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PMFDRULHDRRWFP-UHFFFAOYSA-N
29555	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9466	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	(R)-7BETA-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-2-CARBOHYDROXIMIC ACID|BDBM50027662	-	PUBCHEM	92045024	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-QGZVFWFLSA-N
29556	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9527	(7S)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	BDBM50027661	-	PUBCHEM	118715268	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-KRWDZBQOSA-N
29557	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9528	N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamide	BDBM50026431	-	PUBCHEM	118714377	C21H23N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GIMAODGURWKHJY-UHFFFAOYSA-N
29558	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9529	N-Hydroxy-5-(1-phenylpyrazol-3-yl)pentanamide	BDBM50026430	-	PUBCHEM	118714371	C14H17N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SRBLEOJYOQUWOH-UHFFFAOYSA-N
29559	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9530	5-[1-[(4-Anilinophenyl)methyl]pyrazol-3-yl]-N-hydroxypentanamide	BDBM50026429	-	PUBCHEM	118714376	C21H24N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XXOUJCCBKBTDDB-UHFFFAOYSA-N
29560	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29561	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Salvador LA (2014)	25147612	224860	9531	(5R,8S,11S)-5-Methyl-11-[(E)-4-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]but-1-enyl]-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione	BDBM50101331	-	PUBCHEM	118712502	C42H54N8O8S6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VXQMEGLYMWVBHB-UOLLFOIHSA-N
29562	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Salvador LA (2014)	25147612	224860	9532	Largazole Thiol	LARGAZOLE THIOL|BDBM50020912	-	PUBCHEM	56663191	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-FJNFOTEGSA-N
29563	124227	84727	-	SPSB2	GRCC9|SSB2	9606	Homo sapiens	unknown	target	Yap BK (2014)	25068993	224861	9533	2-[(4S,7S,10S,13S,16S,19S,22S,25R)-25-Acetamido-7,10,13-tris(2-amino-2-oxoethyl)-16-[(2S)-butan-2-yl]-4-carbamoyl-6,9,12,15,18,21,24-heptaoxo-22-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23-heptazacyclohexacos-19-yl]acetic acid	BDBM50055509	-	PUBCHEM	118711530	C35H56N12O14S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VXFIYXDXPBZJRN-VNDFSXJLSA-N
29564	124227	84727	-	SPSB2	GRCC9|SSB2	9606	Homo sapiens	unknown	target	Yap BK (2014)	25068993	224861	9534	(3S)-3-[[(2S)-2-[[(2R)-2-Acetamido-3-sulfanylpropanoyl]amino]-3-methylbutanoyl]amino]-4-[[(2S,3S)-1-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid	BDBM50055507	-	PUBCHEM	102369413	C35H58N12O14S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CWCPBBZVUALKSD-HFOKRWRUSA-N
29565	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	unknown	target	Zhang W (2014)	25068800	224862	9535	BDBM50055496	-	-	CHEMBL	CHEMBL3326006	C28H40N6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MJSHVHLADKXCML-RQNOJGIXSA-N
29566	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9536	(2r)-2-Benzyl-3-[3-({[4-(Piperidin-1-Yl)benzoyl]amino}methyl)-4-Propoxyphenyl]propanoic Acid	Q27459965|(2R)-2-BENZYL-3-[3-({[4-(PIPERIDIN-1-YL)BENZOYL]AMINO}METHYL)-4-PROPOXYPHENYL]PROPANOIC ACID|(2R)-2-BENZYL-3-[3-[[(4-PIPERIDIN-1-YLBENZOYL)AMINO]METHYL]-4-PROPOXYPHENYL]PROPANOIC ACID|MEKT-28|EK8|BDBM50050557	-	PUBCHEM	56929502	C32H38N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ISYAJDFASPMBOB-HHHXNRCGSA-N
29567	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9537	(2R)-2-[[3-[[[4-(Azocan-1-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	(R)-2-[3-[[[4-(OCTAHYDROAZOCINE-1-YL)BENZOYL]AMINO]METHYL]-4-(PROPYLOXY)BENZYL]-3-PHENYLPROPANOIC ACID|BDBM50050556	-	PUBCHEM	102313443	C34H42N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NLXAFEDDAOLUIF-GDLZYMKVSA-N
29568	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9538	(2R)-2-[[3-[[[4-(Azonan-1-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	BDBM50050555	-	PUBCHEM	118708437	C35H44N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LEXLSPDBTSINAM-SSEXGKCCSA-N
29569	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9539	(2R)-2-Benzyl-3-[4-propoxy-3-[[[4-(3,3,5,5-tetramethylpiperidin-1-yl)benzoyl]amino]methyl]phenyl]propanoic acid	BDBM50050554	-	PUBCHEM	118708440	C36H46N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CTTGJGHAKDHCCV-GDLZYMKVSA-N
29570	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9540	(2R)-2-[[3-[[[4-(8-Azabicyclo[3.2.1]octan-8-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	(R)-2-[3-[[[4-(8-AZABICYCLO[3.2.1]OCTANE-8-YL)BENZOYL]AMINO]METHYL]-4-(PROPYLOXY)BENZYL]-3-PHENYLPROPANOIC ACID|BDBM50050553	-	PUBCHEM	102313442	C34H40N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JRGNQRQWJGAPES-WWUHRCHBSA-N
29571	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9541	(2R)-2-[[3-[[[4-(9-Azabicyclo[3.3.1]nonan-9-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	BDBM50050552	-	PUBCHEM	118708441	C35H42N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HTWMBKHFCRGFJX-WHIWCKBPSA-N
29572	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9542	(2R)-2-[[3-[[[4-(3-Azabicyclo[3.2.1]octan-3-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	BDBM50050551	-	PUBCHEM	118708442	C34H40N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SOCVTCXYXPQYPF-VMJMFXBVSA-N
29573	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Tanaka Y (2014)	25017035	224863	9543	(2R)-2-[[3-[[[4-(2-Azatricyclo[3.3.1.13,7]decan-2-yl)benzoyl]amino]methyl]-4-propoxyphenyl]methyl]-3-phenylpropanoic acid	BDBM50050550	-	PUBCHEM	118708443	C36H42N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GRIHSHBOOIEZBN-YQNGJPPUSA-N
29574	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9544	(E)-N-Hydroxy-3-[4-[[5-(naphthalen-1-ylmethyl)-1,3,4-oxadiazol-2-yl]methyl]phenyl]prop-2-enamide	N-HYDROXY-3-[4-[5-(1-NAPHTHYLMETHYL)-1,3,4-OXADIAZOLE-2-YLMETHYL]PHENYL]PROPENEAMIDE|BDBM50047967	-	PUBCHEM	102366363	C23H19N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DQHBWINPWGGELF-OUKQBFOZSA-N
29575	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9545	(E)-N-Hydroxy-3-[4-[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]phenyl]prop-2-enamide	BDBM50047966	-	PUBCHEM	118707836	C20H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MTSNUBCDRYSBCQ-JXMROGBWSA-N
29576	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9546	(E)-N-Hydroxy-3-[4-[5-(naphthalen-1-ylmethyl)-1,3,4-oxadiazol-2-yl]phenyl]prop-2-enamide	BDBM50047965	-	PUBCHEM	118707835	C22H17N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LBRVMWDZJHBLGD-JLHYYAGUSA-N
29577	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29578	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Chen F (2014)	24944733	224865	9532	Largazole Thiol	LARGAZOLE THIOL|BDBM50020912	-	PUBCHEM	56663191	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-FJNFOTEGSA-N
29579	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9547	BDBM50022113	-	-	CHEMBL	CHEMBL3298231	C25H32N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AYMVSAPTKYQTRO-FEHRVWHQSA-N
29580	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9548	CID 90645434	4-ethyl-3-[(2-methyl-2-phenylpropyl)amino]isoindol-1-one|BDBM50022112	-	PUBCHEM	90645434	C20H22N2O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HUHNFFKPYZJMIB-UHFFFAOYSA-N
29581	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9549	2-Chloro-5-methoxy-N-(2-methyl-2-phenylpropyl)quinazolin-4-amine	929022-63-9|2-CHLORO-5-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)QUINAZOLIN-4-AMINE|4-QUINAZOLINAMINE,2-CHLORO-5-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)-|ZINC34949037|BDBM50022111	-	PUBCHEM	16051050	C19H20ClN3O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLEQOKDDRKNDTM-UHFFFAOYSA-N
29582	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9459	4-Methoxy-N-(2-methyl-2-phenylpropyl)-1,2-benzoxazol-3-amine	4-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)-1,2-BENZOXAZOL-3-AMINE|BDBM50022110	-	PUBCHEM	16050462	C18H20N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FRLKYVJLDPLCNR-UHFFFAOYSA-N
29583	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9550	4-Ethyl-N-(2-methyl-2-phenylpropyl)-1,2-benzothiazol-3-amine	BDBM50022109	-	PUBCHEM	90645433	C19H22N2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IKPLYVUNYODPGZ-UHFFFAOYSA-N
29584	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9551	5-Methoxy-4-[(2-methyl-2-phenylpropyl)amino]-1H-quinazolin-2-one	5-METHOXY-4-[(2-METHYL-2-PHENYLPROPYL)AMINO]-1H-QUINAZOLIN-2-ONE|BDBM50022108	-	PUBCHEM	16102139	C19H21N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAYXJKGOWYBZSE-UHFFFAOYSA-N
29585	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Johnson JA (2014)	24881565	224866	9552	8-Methoxy-N-(2-methyl-2-phenylpropyl)isoquinolin-1-amine	ZINC34948862|8-METHOXY-N-(2-METHYL-2-PHENYLPROPYL)ISOQUINOLIN-1-AMINE|BDBM50022107	-	PUBCHEM	16050952	C20H22N2O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WZDLNTAETYKZDN-UHFFFAOYSA-N
29586	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9553	N-[7-(Hydroxyamino)-7-oxoheptyl]-2-methoxyquinoline-6-carboxamide	BDBM50044648	-	PUBCHEM	117829456	C18H23N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VVZXDYPDBYYVAY-UHFFFAOYSA-N
29587	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9554	N-[7-(Hydroxyamino)-7-oxoheptyl]-1-methyl-2-oxoquinoline-6-carboxamide	BDBM50044646	-	PUBCHEM	117829462	C18H23N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FVXNWIVUIWQBNB-UHFFFAOYSA-N
29588	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9555	N-[7-(Hydroxyamino)-7-oxoheptyl]-4,4-dimethyl-2-oxo-1,3-dihydroquinoline-6-carboxamide	BDBM50044645	-	PUBCHEM	86581005	C19H27N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OEQQELYWLWKXKU-UHFFFAOYSA-N
29589	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9556	N'-Hydroxy-N-(2-oxo-1H-quinolin-6-yl)octanediamide	BDBM50044640	-	PUBCHEM	117829479	C17H21N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMKXBBIZQUFLCC-UHFFFAOYSA-N
29590	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9557	BDBM50033636	-	-	CHEMBL	CHEMBL3309297	C22H29N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RIHKXPFNMAZMOA-KTRQRASZSA-N
29591	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Johnson TW (2014)	24819116	224868	9558	Lorlatinib	PF06463922(LORLATINIB)|BCP10287|ZINC98208524|PFE-PKIS 10|D11012|(10R)-7-AMINO-12-FLUORO-10,15,16,17-TETRAHYDRO-2,10,16-TRIMETHYL-15-OXO-2H-4,8-METHENOPYRAZOLO[4,3-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE|HY-12215|7-AMINO-12-FLUORO-2,10,16-TRIMETHYL-15-OXO-10,15,16,17-TETRAHYDRO-2H-8,4-(METHENO)PYRAZOLO(4,3-H)(2,5,11)BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE|CS-3983|S7536|DB12130|AK175603|PF 06463922|GTPL7476|PF-06463922 LORLATINIB|LORLATINIB,PF-06463922|LORLATINIBUM|OSP71S83EU|LORATINIB|PF06463922|PF-06463922|EX-A828|UNII-OSP71S83EU|A14207|LORVIQUA|LORBRENA|(10R)-7-AMINO-12-FLUORO-2,10,16-TRIMETHYL-15-OXO-10,15,16,17-TETRAHYDRO-2H-8,4-(METHENO)PYRAZOLO[4,3-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE|1454846-35-5|NCGC00386417-02|C21H19FN6O2|J-690185|(10R)-7-AMINO-12-FLUORO-2,10,16-TRIMETHYL-15-OXO-10,15,16,17-TETRAHYDRO-2H-8,4-(METHENO)PYRAZOLO[4,3-H][2,5,11]-BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE|4CLI|2H-4,8-METHENOPYRAZOLO(4,3-H)(2,5,11)BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE, 7-AMINO-12-FLUORO-10,15,16,17-TETRAHYDRO-2,10,16-TRIMETHYL-15-OXO-, (10R)-|CCG-268718|LORLATINIB [USAN:INN]|AKOS027250753|LORBRENA (TN)|LORLATINIB (JAN/USAN/INN)|KS-00000T6C|2H-4,8-METHENOPYRAZOLO[4,3-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE, 7-AMINO-12-FLUORO-10,15,16,17-TETRAHYDRO-2,10,16-TRIMETHYL-15-OXO-, (10R)-|Q27285820|(10R)-7-AMINO-12-FLUORO-2,10,16-TRIMETHYL-15-OXO-10,15,16,17-TETRAHYDRO-2H-4,8-METHENOPYRAZOLO[4,3-H][2,5,11]BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE|MFCD28144520|4CLJ|2641AH|NCGC00386417-13|LORLATINIB|BDBM50018830	-	PUBCHEM	71731823	C21H19FN6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IIXWYSCJSQVBQM-LLVKDONJSA-N
29592	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	unknown	target	Kawamura S (2014)	24814885	224869	9559	(2R,3S)-3-[(2S)-Butan-2-yl]-4-oxo-N-[4-phenylmethoxy-3-(phenylmethoxymethyl)butyl]oxetane-2-carboxamide	BDBM50007208	-	PUBCHEM	90655062	C27H35NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SODXRIYSSYNQGD-KSNOWIBYSA-N
29593	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	unknown	target	Kawamura S (2014)	24814885	224869	9560	Benzyl N-[(2S)-1-[[(2R)-1-[(1R,2S)-2-[[(2R,3S)-3-[(2S)-butan-2-yl]-4-oxooxetane-2-carbonyl]amino]cyclopropyl]-4-phenylbutan-2-yl]amino]-1-oxopropan-2-yl]carbamate	BDBM50007207	-	PUBCHEM	90655061	C32H41N3O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YUZQDEBWPUFQAF-RBFWQIJRSA-N
29594	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	unknown	target	Zhang J (2014)	24767818	224870	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
29595	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	unknown	target	Zhang J (2014)	24767818	224870	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
29596	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	9393	Ricolinostat	SW219836-1|ZINC89630354|W-5979|AS-73344|D10661|ROCILINOSTAT (ACY-1215)|GTPL7010|ROCILINOSTAT|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]PYRIMIDINE-5-CARBOXAMIDE|ACY-63|DTXSID40157148|RICOLINOSTAT (USAN/INN)|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)-|CCG-269054|AK151416|7-{[2-(DIPHENYLAMINO)PYRIMIDIN-5-YL]FORMAMIDO}-N-HYDROXYHEPTANAMIDE|SMR004702950|EX-A139|UNII-WKT909C62B|ACN-030031|S8001|AH4|CS-0965|DB12376|Q27088553|NS00073045|ACY-1215|1316214-52-4|SB17054|CC-661|HMS3426C09|US8609678, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE [26]|AB0032517|BCP06028|A11940|X5832|AC-30258|2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE|MLS006011181|N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-2-(N-PHENYLANILINO)PYRIMIDINE-5-CARBOXAMIDE|HY-16026|WKT909C62B|NCGC00345802-05|J-690127|ACY1215|AX8288032|AKOS024259260|RICOLINOSTAT (ACY-1215)|RICOLINOSTAT [USAN:INN]|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-5-PYRIMIDINECARBOXAMIDE|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-|NCGC00345802-01|RICOLINOSTAT|HMS3653F17|KS-00000SAV|BDBM50439674	-	PUBCHEM	53340666	C24H27N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGZYDVAGYRLSKP-UHFFFAOYSA-N
29597	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	9561	(E)-N-Hydroxy-3-(3-pyrrolo[2,3-b]pyridin-1-ylsulfonylphenyl)prop-2-enamide	N-HYDROXY-3-[3-(1H-PYRROLO[2,3-B]PYRIDINE-1-YLSULFONYL)PHENYL]PROPENEAMIDE|(E)-N-HYDROXY-3-(3-PYRROLO[2,3-B]PYRIDIN-1-YLSULFONYLPHENYL)PROP-2-ENAMIDE|BDBM50015233	-	PUBCHEM	86765212	C16H13N3O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OXPJGPURVBXIAP-VOTSOKGWSA-N
29598	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29599	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Zhang J (2014)	24751157	224872	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
29600	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Zhang J (2014)	24751157	224872	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
29601	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	9562	(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamide	(E)-N-HYDROXY-3-[4-(4-METHOXYPHENYL)PHENYL]PROP-2-ENAMIDE|N-HYDROXY-E-3-(4''-METHOXYBIPHENYL-4-YL)-ACRYLAMIDE|BDBM50293361	-	PUBCHEM	15986509	C16H15NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WKQPXLKFQLGQSM-NYYWCZLTSA-N
29602	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	9563	(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamide	N-HYDROXY-E-3-(4''-HYDROXYBIPHENYL-4-YL)-ACRYLAMIDE|(E)-N-HYDROXY-3-[4-(4-HYDROXYPHENYL)PHENYL]PROP-2-ENAMIDE|BDBM50293358	-	PUBCHEM	15986418	C15H13NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGGQEULGVBEMAL-XCVCLJGOSA-N
29603	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29604	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29605	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2014)	24694055	224874	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29606	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Taddei M (2014)	24588105	224875	9564	1-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-[4-(morpholin-4-ylmethyl)phenyl]triazole-4-carboxamide	BDBM50008222	-	PUBCHEM	90655296	C30H40N6O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IBHAGSBJXPUIFA-UHFFFAOYSA-N
29607	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Taddei M (2014)	24588105	224875	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29608	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Baruchello R (2014)	24565573	224876	9565	5-(2,4-Dihydroxy-5-propan-2-ylbenzoyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-6,7-dihydro-4H-[1,2]oxazolo[4,5-c]pyridine-3-carboxamide	BDBM50007730	-	PUBCHEM	86302594	C24H32N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MSHYQCFSRGHYAU-UHFFFAOYSA-N
29609	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Baruchello R (2014)	24565573	224876	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29610	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	unknown	target	Jiang ZY (2014)	24512214	163212	9409	2,2'-(Naphthalene-1,4-diylbis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetic acid	COMPOUND 2 [PMID: 24512214]|CPUY192018|2,2'-(NAPHTHALENE-1,4-DIYLBIS(((4-METHOXYPHENYL)SULFONYL)AZANEDIYL))DIACETIC ACID|2,2'-[1,4-NAPHTHALENEDIYLBIS[(4-METHOXYPHENYLSULFONYL)IMINO]]BISACETIC ACID|BRD-K55096910-001-01-4|COMPOUND 18E [PMID: 26258437]|GTPL9710|1567836-15-0|2-[[4-[CARBOXYMETHYL-(4-METHOXYPHENYL)SULFONYLAMINO]NAPHTHALEN-1-YL]-(4-METHOXYPHENYL)SULFONYLAMINO]ACETIC ACID|BDBM50006932	-	PUBCHEM	73330369	C28H26N2O10S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSIQJUNYMMCTB-UHFFFAOYSA-N
29611	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	unknown	target	Jiang ZY (2014)	24512214	163212	9566	(4S)-5-[[(2S)-1-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[2-[[(2S,3R)-2-[[(2S)-4-carboxy-2-[[(2S)-4-carboxy-2-[[(2S)-3-carboxy-2-[[(2S)-2-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)carbamothioylamino]-4-methylpentanoyl]amino]propanoyl]amino]butanoyl]amino]butanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-oxopentanoic acid	BDBM50006930	-	PUBCHEM	90655040	C67H81N11O23S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WHORBCNXCLZUFL-HDFZMCSMSA-N
29612	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	unknown	target	Hasegawa M (2014)	24321833	224877	9567	Z-Leu-leu-leu-al	CBZ-LEU-LEU-LEU-AL|Z-LLL|BRD-0970|BENZYLOXYCARBONYL-LEU-LEU-LEUCINAL|COMPOUND 5B [PMID: 16686537]|DTXSID3042639|KBIOSS_000030|EX-A1500|MFCD00674886|KBIO3_000059|CARBOBENZOXYL-LEUCINYL-LEUCINYL-LEUCINAL-H|NCGC00161679-02|X7579|MG-132 [Z-LEU-LEU-LEU-CHO]|CCG-207860|Z-LEU-LEU-LEUCINAL|Q3272916|BRD0970|MG-132-1|AOB4946|BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE|NCGC00161679-01|UNM000011053701|L-LEUCINAMIDE, N-((PHENYLMETHOXY)CARBONYL)-L-LEUCYL-N-(1-FORMYL-3-METHYLBUTYL)-, (S)-|SR-01000864598-1|CBZ-L-LEU-L-LEU-L-LEU-H|CCG-208036|N-BENZYLOXYCARBONYL-L-LEUCYL-L-LEUCYL-L-LEUCINAL|LLL CPD|Z-LEU-LEU-LEU-AL, >=90% (HPLC)|Z-LLLAL|BENZYLOXYCARBONYL-LEU-LEU-LEU-ALDEHYDE|MG 132|CS-0471|BENZYL N-[(1S)-3-METHYL-1-[[(1S)-3-METHYL-1-[[(2S)-4-METHYL-1-OXO-PENTAN-2-YL]CARBAMOYL]BUTYL]CARBAMOYL]BUTYL]CARBAMATE|SC-93546|133407-82-6|SW219780-1|KBIO3_000060|ZX-AFC000065|MG132/MG-132/|S2619|Z-LEU-LEU-LEU-AL|PHENYLMETHYL N-[(2S)-4-METHYL-1-[[(2S)-4-METHYL-1-[[(2S)-4-METHYL-1-OXOPENTAN-2-YL]AMINO]-1-OXOPENTAN-2-YL]AMINO]-1-OXOPENTAN-2-YL]CARBAMATE|CARBOBENZOXY-L-LEUCYL-L-LEUCYL-L-LEUCINAL|BIC3742|IDI1_033780|MG-132|BRD-K60230970-001-06-8|CARBOBENZOXY-LEUCYL-LEUCYL-LEUCINAL|Z-LEU-LEU-LEU-ALDEHYDE|HMS3402B12|CBZ-L-LEU-L-LEU-L-LEU-CHO|ABP000958|BRD-K60230970-001-08-4|(S)-N-((PHENYLMETHOXY)CARBONYL)-L-LEUCYL-N-(1-FORMYL-3-METHYLBUTYL)-L-LEUCINAMIDE|BIO2_000030|Z-L-LEU-L-LEU-L-LEU-H|(S)-4-METHYL-2-(3-PHENYL-PROPIONYLAMINO)-PENTANOIC ACID [(S)-1-((S)-1-FORMYL-3-METHYL-BUTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE|ACN-047884|Z-LLL-ALDEHYDE|CBZ-LEU-LEU-LEUCINAL|N-[(BENZYLOXY)CARBONYL]-L-LEUCYL-N-[(1S)-1-FORMYL-3-METHYLBUTYL]-L-LEUCINAMIDE|NCGC00161679-03|BENZYL(S)-4-METHYL-1-((S)-4-METHYL-1-((S)-4-METHYL-1-OXOPENTAN-2-YLAMINO)-1-OXOPENTAN-2-YLAMINO)-1-OXOPENTAN-2-YLCARBAMATE|AS-55854|HY-13259|W-5117|L-LEUCINAMIDE, N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N1-[(1S)-1-FORMYL-3-METHYLBUTYL]-|BRD-K60230970-001-05-0|SB19111|MLS006011220|N-[(BENZYLOXY)CARBONYL]-L-LEUCYL-N-[(2S)-4-METHYL-1-OXOPENTAN-2-YL]-L-LEUCINAMIDE|CARBOBENZOXY-LEU-LEU-LEUCINAL|{1-[1-(1-FORMYL-3-METHYL-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL]-3-METHYL-BUTYL}-CARBAMIC ACID BENZYL ESTER|(R)-MG132|HMS1361B12|BSPBIO_001310|CC-245|HMS1989B12|C26H41N3O5|BIO2_000510|Z-LLL-H|MG132|PI-102|(S)-MG132|BENZYL N-[(1S)-1-[[(1S)-1-[[(1S)-1-FORMYL-3-METHYL-BUTYL]CARBAMOYL]-3-METHYL-BUTYL]CARBAMOYL]-3-METHYL-BUTYL]CARBAMATE|UNII-RF1P63GW3K|BENZYL ((S)-4-METHYL-1-(((S)-4-METHYL-1-(((S)-4-METHYL-1-OXOPENTAN-2-YL)AMINO)-1-OXOPENTAN-2-YL)AMINO)-1-OXOPENTAN-2-YL)CARBAMATE|SMR002530629|{(S)-1-[(S)-1-((S)-1-FORMYL-3-METHYL-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL]-3-METHYL-BUTYL}-CARBAMIC ACID BENZYL ESTER|KS-00000XP9|QCR-183|BRD-K60230970-001-04-3|1211877-36-9|NCGC00161679-04|BRD-K60230970-001-07-6|KBIO2_005166|ZINC13476439|GTPL8616|BCBCMAP01_000028|HMS1791B12|N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N-[(1S)-1-FORMYL-3-METHYLBUTYL]-L-LEUCINAMIDE|KBIO2_002598|L-LEUCINAMIDE, N-((PHENYLMETHOXY)CARBONYL)-L-LEUCYL-N-((1S)-1-FORMYL-3-METHYLBUTYL)-|Z-LLL-CHO|AKOS027420457|BENZYLOXYCARBONYL-LEUCYL-LEUCYL-LEUCINAL|ZLLL-CHO|Z-LEU-LEU-LEU-H|KBIO2_000030|N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N-(1-FORMYL-3-METHYLBUTYL)-(S)-L-LEUCINAMIDE|KBIOGR_000030|BENZYL (S)-4-METHYL-1-((S)-4-METHYL-1-((S)-4-METHYL-1-OXOPENTAN-2-YLAMINO)-1-OXOPENTAN-2-YLAMINO)-1-OXOPENTAN-2-YLCARBAMATE|CTK8F0239|CBZ-LEU-LEU-LEU-H|AB0033810|{1-[(S)-(S)-1-((S)-1-FORMYL-3-METHYL-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL]-3-METHYL-BUTYL}-CARBAMIC ACID BENZYL ESTER|RF1P63GW3K|BRD-K60230970-001-10-0|ZLLLAL|BDBM50069985	-	PUBCHEM	462382	C26H41N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TZYWCYJVHRLUCT-VABKMULXSA-N
29613	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18440229	224878	9568	1-[5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)thiophen-2-yl]-2,2-difluoroethan-1-one	THIOPHENE DERIVATIVE, 15H|1-[5-(2,3-DIHYDRO-1H-INDOL-1-YLCARBONYL)THIOPHEN-2-YL]-2,2-DIFLUOROETHAN-1-ONE|BDBM25172	-	PUBCHEM	25023808	C15H11F2NO2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WZGNPOPOCGTSMZ-UHFFFAOYSA-N
29614	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18440229	224878	9569	CID 24857909	THIOPHENE DERIVATIVE, 3I|N-METHYL-N-(QUINOXALIN-6-YLMETHYL)-5-(2,2,2-TRIFLUOROACETYL)THIOPHENE-2-CARBOXAMIDE|BDBM25163	-	PUBCHEM	24857909	C17H12F3N3O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RLNCISDDCDFAHS-UHFFFAOYSA-N
29615	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	9570	4-[[1-(3-Aminopropyl)triazol-4-yl]methylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	BDBM50377688	-	PUBCHEM	44449588	C20H31N7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VYBKJKUFXIAVJM-UHFFFAOYSA-N
29616	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	9571	5-[3-[4-[[4-[[7-(Hydroxyamino)-7-oxoheptyl]carbamoyl]anilino]methyl]triazol-1-yl]propylcarbamothioylamino]-2-(3-oxoxanthen-9-yl)benzoic acid	BDBM50377687	-	PUBCHEM	44448637	C41H42N8O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SIKVCWVCYQGEQT-UHFFFAOYSA-N
29617	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29618	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29619	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nakao Y (2008)	18397826	224880	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29620	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Casimiro-Garcia A (2008)	18394907	224881	9572	(S)-3-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-pyrrol-1-yl-propionic acid	(S)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PYRROL-1-YL-PROPIONIC ACID|(S)-3-[4-[2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY]PHENYL]-2-PYRROL-1-YL-PROPIONIC ACID|(2S)-3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PYRROL-1-YLPROPANOIC ACID|(ALPHAS)-ALPHA-(1H-PYRROLE-1-YL)-4-[2-(2-PHENYL-5-METHYL-4-OXAZOLYL)ETHOXY]BENZENEPROPIONIC ACID|PHENYLPROPANOIC ACID DERIVATIVE, 7|BDBM34017	-	PUBCHEM	9866595	C25H24N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OCWDFPOKWYMLGH-QHCPKHFHSA-N
29621	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Finlay HJ (2008)	18374568	224882	9573	N-[(8S)-8-[(4-Ethylphenyl)sulfonylamino]-5,6,7,8-tetrahydronaphthalen-2-yl]-N-[(6-methylpyridin-2-yl)methyl]-3-phenylpropanamide	BDBM50376745	-	PUBCHEM	44450682	C34H37N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OZIVHWHJMJVZCH-XIFFEERXSA-N
29622	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Finlay HJ (2008)	18374568	224882	9574	N-[(3S,4R)-6-[(2S)-2-[(2,6-Dimethylanilino)methyl]pyrrolidine-1-carbonyl]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-4-ethylbenzenesulfonamide	RAC-TRANS-N-(6-((S)-2-((2,6-DIMETHYLPHENYLAMINO)METHYL)PYRROLIDINE-1-CARBONYL)-3-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-4-YL)-4-ETHYLBENZENESULFONAMIDE|N-((3S,4R)-6-((S)-2-((2,6-DIMETHYLPHENYLAMINO)METHYL)PYRROLIDINE-1-CARBONYL)-3-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-4-YL)-4-ETHYLBENZENESULFONAMIDE|BDBM50211535	-	PUBCHEM	17752926	C33H41N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZGNURVKJDROBKC-RVQNBHMFSA-N
29623	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Finlay HJ (2008)	18374568	224882	9575	N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-indan-5-yl]-3-methoxy-benzamide	N-((2R,3R)-3-(4-ETHYLPHENYLSULFONAMIDO)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-3-METHOXYBENZAMIDE|N-[3-(4-ETHYL-BENZENESULFONYLAMINO)-2-HYDROXY-INDAN-5-YL]-3-METHOXY-BENZAMIDE|BDBM50099581	-	PUBCHEM	17748224	C25H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KCRNOVULDSNKBZ-DNQXCXABSA-N
29624	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18370373	224883	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29625	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	4802	Belinostat	UNII-F4H96P17NZ|NSC-726630|ZINC3818726|ABP000140|866323-14-0|SC-71101|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|SW219445-1|NSC726630|BELEODAQ|BCPP000351|EX-A180|PX 105684|QCR-181|BCP01741|BRD-K17743125-001-01-9|GTPL7496|(E)-N-HYDROXY-3-(3-(N-PHENYLSULFAMOYL)PHENYL)ACRYLAMIDE|BELINOSTAT - PXD101|SB16466|CC-489|AOB87787|BELINOSTAT|AX8144528|MLS006011091|AC-25046|AB0007889|BELINOSTAT (PXD101)|BELINOSTAT,PXD101, PX105684|W-5363|(E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|414864-00-9|D08870|(E)-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENEHYDROXAMIC ACID|BELINOSTAT [USAN:INN]|SMR004702879|Q4882925|E-BELINOSTAT|BELINOSTAT (PXD101)|PXD101|PXD 101|N-HYDROXY-3-(3-PHENYLSULPHAMOYLPHENYL)ACRYLAMIDE|API0003555|BELINOSTAT (USAN/INN)|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]ACRYLAMIDE|BELEODAQ (TN)|PUBCHEM22405|NCGC00263155-05|(E)-N-HYDROXY-3-(3-PHENYLSULFAMOYL-PHENYL)-ACRYLAMIDE|PXD-101|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PR|S1085|LS41098|PX-105684|BELINOSTAT PH3|N-HYDROXY-3-(3-PHENYLSULFAMOYLPHENYL)ACRYLAMIDE|EC-000.2286|BELINOSTAT/PXD101,PX105684/|5OG|DTXSID60194378|2-PROPENAMIDE, N-HYDROXY-3-(3-((PHENYLAMINO)SULFONYL)PHENYL)-, (2E)-|BCP9000386|PX105684|F4H96P17NZ|N-HYDROXY-3-[(PHENYLAMINO)SULFONYL]-TRANS-CINNAMAMIDE|AS-17068|BELINOSTAT(RANDOM CONFIGURATION)|A25012|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE|AKOS025401741|N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE|CCG-208758|2-PROPENAMIDE, N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-, (2E)-|DB05015|J-523584|BDBM25150	beleodaq	DRUGBANK	DB05015	C15H14N2O4S	small molecule	L01XX49	866323-14-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NCNRHFGMJRPRSK-MDZDMXLPSA-N
29626	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	9576	Dacinostat	AS-74728|(2E)-N-HYDROXY-3-(4-{[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL}PHENYL)PROP-2-ENAMIDE|S1095|ABP000476|AOB87324|SB19288|404951-53-7|Z-3310|(2E)-N-HYDROXY-3-[4-({(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO}METHYL)PHENYL]PROP-2-ENAMIDE|MLS006011098|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-2-PROPENAMIDE|LAQ824 (NVP-LAQ824,DACINOSTAT)|AK174336|139303-EP2292617A1|EX-A2226|LAQ824; DACINOSTAT; NVP-LAQ824|ZINC1494627|Q27076972|DACINOSTAT (NVP-LAQ824, LAQ824)|V10P524501|BCP9000839|UNII-V10P524501|2-PROPENAMIDE, N-HYDROXY-3-[4-[[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-, (2E)-|A825135|LAQ824 (DACINOSTAT)|139303-EP2270008A1|X7607|BRD-K56957086-001-02-2|DACINOSTAT [INN]|LAQ824/|CS-1974|X7530|LS-192513|NVP-LAQ824|(2E)-N-HYDROXY-3-(4-({(2-HYDROXYETHYL)(2-(1H-INDOL-3-YL)ETHYL)AMINO}METHYL)PHENYL)PROPENAMIDE|HY-13606|DTXSID1041055|EC-000.2469|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METH YL]PHENYL]PROP-2-ENAMIDE|NVP-LAQ 824|GTPL7497|2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-HYDROXYETHYL)(2-(1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-|LAQ824,NVP-LAQ824|LAQ-824|CCG-208761|LAQ824|SMR004701446|N-HYDROXY-3-[4-[[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]-AMINO]METHYL]PHENYL]-2E-2-PROPENAMIDE|SW219385-1|SMR004702886|BCP01747|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]PROP-2-ENAMIDE|AKOS015899788|DACINOSTAT|MLS006010418|(E)-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-N-OXIDANYL-PROP-2-ENAMIDE|BDBM19428	-	PUBCHEM	6445533	C22H25N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWDQBBCUWLSASG-MDZDMXLPSA-N
29627	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29628	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Wang W (2008)	18291645	224885	9577	(2S,3S)-1-(4-Tert-butylphenyl)-3-[[3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-4-oxoazetidine-2-carboxylic acid	BDBM50372118	-	PUBCHEM	10369999	C33H34N2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XRVNSFDHOMAYDC-YTMVLYRLSA-N
29629	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Wang W (2008)	18291645	224885	9578	(2S,3S)-1-(4-Methoxyphenyl)-3-[[3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-4-oxoazetidine-2-carboxylic acid	Q27465016|(2S,3S)-1-(4-METHOXYPHENYL)-3-(3-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)BENZYL)-4-OXOAZETIDINE-2-CARBOXYLIC ACID|REW|(2S,3S)-1-(4-METHOXYPHENYL)-3-{3-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]BENZYL}-4-OXOAZETIDINE-2-CARBOXYLIC ACID|BDBM50372107	-	PUBCHEM	10391684	C30H28N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DKIUFVFEAUCDLY-BDYUSTAISA-N
29630	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Wang W (2008)	18291645	224885	9579	(2S,3S)-1-(4-Methoxyphenyl)-3-[[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-4-oxoazetidine-2-carboxylic acid	BDBM50372105	-	PUBCHEM	9983904	C30H28N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WTRWFOXPPRLKFP-BDYUSTAISA-N
29631	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Wang W (2008)	18291645	224885	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29632	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	9580	2-Propenamide, N-hydroxy-3-(4-(((2-hydroxyethyl)(2-(1H-indol-2-yl)ethyl)amino)methyl)phenyl)-	591207-53-3|LAQ 824|2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-HYDROXYETHYL)(2-(1H-INDOL-2-YL)ETHYL)AMINO)METHYL)PHENYL)BDBM50372470	-	PUBCHEM	44456564	C22H25N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FGJCGXHQLHHNFO-MDZDMXLPSA-N
29633	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	9581	(2S)-2-[(1-Methylpiperidin-2-yl)amino]-8-oxo-N-(4-phenyl-1,3-thiazol-2-yl)nonanamide	BDBM50372446	-	PUBCHEM	44456965	C24H34N4O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KQYOQEZNUIXORM-AIBWNMTMSA-N
29634	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29635	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Witter DJ (2008)	18060775	114009	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29636	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Schaefer S (2008)	18054239	123981	9582	6-[(3S,9S,12R)-3-Benzyl-6,6-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]-N-hydroxyhexanamide	6-((5S,11S,13AR)-5-BENZYL-8,8-DIMETHYL-4,7,10,13-TETRAOXO-TETRADECAHYDRO-3A,6,9,12-TETRAAZA-CYCLOPENTACYCLODODECEN-11-YL)-HEXANOIC ACID HYDROXYAMIDE|6-((9S,13AR)-5-(S)-1-BENZYL-8,8-DIMETHYL-4,7,10,13-TETRAOXO-TETRADECAHYDRO-3A,6,9,12-TETRAAZA-CYCLOPENTACYCLODODECEN-11-YL)-HEXANOIC ACID HYDROXYAMIDE|BDBM50154337	-	PUBCHEM	9806551	C26H37N5O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XWZYWFHHLWISBR-SLFFLAALSA-N
29637	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Potterat O (2007)	18044841	224887	9583	Chlorocyclinone B	METHYL 9-[1-(ACETYLOXYETHYL)]-2-CHLORO-6,8-DIHYDROXY-1-METHOXY-3-METHYL-7,12-DIOXO-7,12-DIHYDROTETRAPHENE-10-CARBOXYLATE|CHLOROCYCLINONE B|BDBM50228360	-	PUBCHEM	24762580	C26H21ClO9	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MFLXCCWOEBQIHW-UHFFFAOYSA-N
29638	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Potterat O (2007)	18044841	224887	9584	Chlorocyclinone C	METHYL 2-CHLORO-6,8-DIHYDROXY-9-{1-[(HYDROXYACETYL)OXY]ETHYL}-1-METHOXY-3-METHYL-7,12-DIOXO-7,12-DIHYDROTETRAPHENE-10-CARBOXYLATE|CHLOROCYCLINONE C|BDBM50228359	-	PUBCHEM	24180661	C26H21ClO10	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMNHPKWXMIGBEL-UHFFFAOYSA-N
29639	114491	9024	HUSSY-12	BRSK2	C11orf7|PEN11B|SAD1|SADA|STK29	9606	Homo sapiens	unknown	target	Bain J (2007)	17850214	224888	6832	Su6656	330161-87-0|NCGC00094279-01|B5839|HMS3648O08|NCGC00015981-09|N,N-DIMETHYL-2-OXO-3-((4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE)INDOLINE-5-SULFONAMIDE|2,3-DIHYDRO-N,N-DIMETHYL-2-OXO-3-[(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE]-1H-INDOLE-5-SULFONAMIDE|EX-A584|4071AH|AKOS015994571|MLS002153475|HMS2232C04|INSOLUTION&TRADE; SU6656|LOPAC0_000979|EU-0100979|NCGC00261664-01|S7774|Q7394936|NCGC00015981-03|1240328-42-0|SU 6656|SR-01000076237-6|HMS3263C19|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE|CCG-205059|SU-6656|SU6656|ES-0024|SU 6656, >=98% (HPLC)|SDCCGSBI-0050952.P003|NCGC00015981-04|NCGC00094279-02|LOPAC-S-9692|NCGC00015981-02|HSCI1_000124|SR-01000076237-1|HMS3229I04|SR-01000076237|CS-3943|GTPL6044|TOX21_500979|DB08039|(Z)-N,N-DIMETHYL-2-OXO-3-((4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)METHYLENE)INDOLINE-5-SULFONAMIDE|MFCD10565928|NCGC00015981-05|NCGC00015981-01|NCGC00015981-06|ZINC3875028|2-OXO-3-[1-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YL)-METH-(Z)-YLIDENE]-2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID DIMETHYLAMIDE|SMR001230828|S 9692|LP00979|BRD-K97354755-001-01-5|HY-B0789|BDBM50307127	-	DRUGBANK	DB08039	C19H21N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LOGJQOUIVKBFGH-YBEGLDIGSA-N
29640	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee S (2007)	17588744	224889	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29641	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9585	N-[4-[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID [2''-(2-AMINO-3-PHENYLPROPIONYLAMINO)-BIPHENYL-4-YL]AMIDE HYDROXYAMIDE|BDBM50214441	-	PUBCHEM	16733294	C29H34N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZYFHRXJYNBDKS-VWLOTQADSA-N
29642	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9586	N-[4-[2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID {2''-[2-AMINO-3-(4-HYDROXY-PHENYL)PROPIONYLAMINO]BIPHENYL-4-YL}AMIDE HYDROXYAMIDE|BDBM50214439	-	PUBCHEM	16733417	C29H34N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BKQJCMOVBFAIQR-VWLOTQADSA-N
29643	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9587	N-[4-[2-[[(2S)-2-Amino-3-(1H-indol-3-yl)propanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID {2''-[2-AMINO-3-(1H-INDOL-3-YL)PROPIONYLAMINO]BIPHENYL-4-YL}AMIDE HYDROXYAMIDE|BDBM50214436	-	PUBCHEM	16733410	C31H35N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ACGVFMBQNSCSQI-SANMLTNESA-N
29644	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9588	1-(4-(Dimethylamino)phenyl)-3-(7-(hydroxyamino)-7-oxoheptyl)urea	7-[[4-(DIMETHYLAMINO)PHENYL]CARBAMOYLAMINO]-N-HYDROXYHEPTANAMIDE|1-(4-(DIMETHYLAMINO)PHENYL)-3-(7-(HYDROXYAMINO)-7-OXOHEPTYL)UREA|7-[3-(4-DIMETHYLAMINO-PHENYL)-UREIDO]-HEPTANOIC ACID HYDROXYAMIDE|7-[3-(4-DIMETHYLAMINOPHENYL)-UREIDO]HEPTANOIC ACID HYDROXYAMIDE|BDBM50214433	-	PUBCHEM	11558827	C16H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZYOHRYKXMFPCNU-UHFFFAOYSA-N
29645	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9589	N'-Hydroxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]octanediamide	OCTANEDIOIC ACID HYDROXYAMIDE [4-(3-NITRO-PHENYL)THIAZOL-2-YL]AMIDE|N'-HYDROXY-N-[4-(3-NITROPHENYL)-1,3-THIAZOL-2-YL]OCTANEDIAMIDE|BDBM50214432	-	PUBCHEM	16733411	C17H20N4O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LJFNWCGSOPRFNA-UHFFFAOYSA-N
29646	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9590	3-[[4-(Dimethylamino)phenyl]methylcarbamoylamino]-N-hydroxypropanamide	8-[3-(4-DIMETHYLAMINOBENZYL)UREIDO]OCTANOIC ACID HYDROXYAMIDE|BDBM50214431	-	PUBCHEM	16733415	C13H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FJIZCQBWUCHHAR-UHFFFAOYSA-N
29647	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9591	N-(Quinolin-8-YL)-6-(2-sulfanylacetamido)hexanamide	828920-13-4|6-(2-MERCAPTOACETYLAMINO)-HEXANOIC ACID QUINOLIN-8-YLAMIDE|N-(8-QUINOLYL)-6-[(MERCAPTOACETYL)AMINO]HEXANAMIDE|N-(QUINOLIN-8-YL)-6-(2-SULFANYLACETAMIDO)HEXANAMIDE|N-QUINOLIN-8-YL-6-[(2-SULFANYLACETYL)AMINO]HEXANAMIDE|HEXANAMIDE, 6-[(MERCAPTOACETYL)AMINO]-N-8-QUINOLINYL-|CTK3D5606|6-(2-MERCAPTO-ACETYLAMINO)-HEXANOIC ACID QUINOLIN-8-YLAMIDE|DTXSID10587453|6-(2-MERCAPTOACETAMIDO)-N-(QUINOLIN-8-YL)HEXANAMIDE|BDBM50161470	-	PUBCHEM	16733414	C17H21N3O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KQBNGYXGCIUPHR-UHFFFAOYSA-N
29648	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2007)	17462888	224890	9592	(3S,4R)-4-[Butyl-(4-ethylphenyl)sulfonylamino]-3-hydroxy-2,2-dimethyl-N-(2-phenylethyl)-3,4-dihydrochromene-6-carboxamide	(3S,4R)-4-(N-BUTYL-4-ETHYLPHENYLSULFONAMIDO)-3-HYDROXY-2,2-DIMETHYL-N-PHENETHYLCHROMAN-6-CARBOXAMIDE|BDBM50211550	-	PUBCHEM	44426357	C32H40N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MJJYOGKDYSSXAT-IHLOFXLRSA-N
29649	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2007)	17462888	224890	9593	N-[(3R,4S)-6-[(2R)-2-[(2,6-Dimethylanilino)methyl]pyrrolidine-1-carbonyl]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-4-ethylbenzenesulfonamide	N-((3R,4S)-6-((R)-2-((2,6-DIMETHYLPHENYLAMINO)METHYL)PYRROLIDINE-1-CARBONYL)-3-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-4-YL)-4-ETHYLBENZENESULFONAMIDE|BDBM50211547	-	PUBCHEM	44426394	C33H41N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZGNURVKJDROBKC-SDDUWZMOSA-N
29650	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2007)	17462888	224890	9594	N-[(3S,4R)-6-(5-Amino-3-phenylpyrazole-1-carbonyl)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-4-ethylbenzenesulfonamide	N-((3S,4R)-6-(5-AMINO-3-PHENYL-1H-PYRAZOLE-1-CARBONYL)-3-HYDROXY-2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-4-YL)-4-ETHYLBENZENESULFONAMIDE|BDBM50211521	-	PUBCHEM	44426329	C29H30N4O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TUAUXGUOYDDDKI-SXOMAYOGSA-N
29651	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2007)	17462888	224890	9595	(3S,4R)-N-(2-Anilinoethyl)-N-ethyl-4-[(4-ethylphenyl)sulfonylamino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carboxamide	(3S,4R)-N-ETHYL-4-(4-ETHYLPHENYLSULFONAMIDO)-3-HYDROXY-2,2-DIMETHYL-N-(2-(PHENYLAMINO)ETHYL)-3,4-DIHYDRO-2H-CHROMENE-6-CARBOXAMIDE|BDBM50211518	-	PUBCHEM	44426325	C30H37N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKIYRCPRFNAXAQ-IZLXSDGUSA-N
29652	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Lloyd J (2007)	17462888	224890	9575	N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-indan-5-yl]-3-methoxy-benzamide	N-((2R,3R)-3-(4-ETHYLPHENYLSULFONAMIDO)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-3-METHOXYBENZAMIDE|N-[3-(4-ETHYL-BENZENESULFONYLAMINO)-2-HYDROXY-INDAN-5-YL]-3-METHOXY-BENZAMIDE|BDBM50099581	-	PUBCHEM	17748224	C25H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KCRNOVULDSNKBZ-DNQXCXABSA-N
29653	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Pochetti G (2007)	17403688	224891	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29654	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Gross MF (2007)	17350840	224892	9575	N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-indan-5-yl]-3-methoxy-benzamide	N-((2R,3R)-3-(4-ETHYLPHENYLSULFONAMIDO)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-3-METHOXYBENZAMIDE|N-[3-(4-ETHYL-BENZENESULFONYLAMINO)-2-HYDROXY-INDAN-5-YL]-3-METHOXY-BENZAMIDE|BDBM50099581	-	PUBCHEM	17748224	C25H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KCRNOVULDSNKBZ-DNQXCXABSA-N
29655	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Devasthale PV (2007)	17292606	224893	9596	2-((3-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)(naphthalen-1-ylmethyl)amino)acetic acid	2-((3-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)BENZYL)(NAPHTHALEN-1-YLMETHYL)AMINO)ACETIC ACID|BDBM50205086	-	PUBCHEM	22087541	C32H30N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NICLRQUMPVQLFM-UHFFFAOYSA-N
29656	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9597	6-[4-[(4-Methylpiperazin-1-yl)methyl]phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine	6-[4-[(4-METHYLPIPERAZIN-1-YL)METHYL]PHENYL]-N-[[(2S)-OXOLAN-2-YL]METHYL]-5-PHENYLFURO[2,3-D]PYRIMIDIN-4-AMINE|(S)-6-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)PHENYL)-5-PHENYL-N-((TETRAHYDROFURAN-2-YL)METHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204590	-	PUBCHEM	44438320	C29H33N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IYUXAJHPXXWFQO-DEOSSOPVSA-N
29657	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9598	Aim-100	5,6-DIPHENYL-4-[(S)-(TETRAHYDROFURAN-2-YL)-METHYL]AMINO FURO[2,3-D]PYRIMIDINE|AIM-100|873305-35-2|EX-A3635|MLS006010340|(S)-5,6-DIPHENYL-N-((TETRAHYDROFURAN-2-YL)METHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|S2212|AIM 100|5,6-DIPHENYL-N-[[(2S)-TETRAHYDRO-2-FURANYL]METHYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|ZINC28879084|N-[[(2S)-OXOLAN-2-YL]METHYL]-5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-AMINE|AKOS024458428|W-5920|NCGC00347279-01|HY-15290|NCGC00347279-04|DTXSID20467671|5,6-DIPHENYL-N-[[(2S)-TETRAHYDROFURAN-2-YL]METHYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|SMR004701402|3426AH|AIM 100;AIM100|CS-0702|BDBM50204589	-	PUBCHEM	11501591	C23H21N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XNFHHOXCDUAYSR-SFHVURJKSA-N
29658	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9599	6-[4-[2-(Dimethylamino)ethoxy]phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine	6-[4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL]-N-[[(2S)-OXOLAN-2-YL]METHYL]-5-PHENYLFURO[2,3-D]PYRIMIDIN-4-AMINE|{6-[4-(2-DIMETHYLAMINO-ETHOXY)-PHENYL]-5-PHENYL-FURO[2,3-D]PYRIMIDIN-4-YL}-(TETRAHYDRO-FURAN-2-(S)-YL-METHYL)-AMINE|(S)-6-(4-(2-(DIMETHYLAMINO)ETHOXY)PHENYL)-5-PHENYL-N-((TETRAHYDROFURAN-2-YL)METHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204587	-	PUBCHEM	44438318	C27H30N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XNSZHQUDPHATEN-QFIPXVFZSA-N
29659	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9600	6-[3-Methoxy-4-(2-piperidin-1-ylethoxy)phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine	6-(3-METHOXY-4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-5-PHENYL-N-(((S)-TETRAHYDROFURAN-2-YL)METHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|6-[3-METHOXY-4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-N-[[(2S)-OXOLAN-2-YL]METHYL]-5-PHENYLFURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204586	-	PUBCHEM	11519350	C31H36N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IOSKHROQBBQEOB-DEOSSOPVSA-N
29660	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9601	N-[[(2S)-Oxolan-2-yl]methyl]-5-phenyl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]furo[2,3-d]pyrimidin-4-amine	N-[[(2S)-OXOLAN-2-YL]METHYL]-5-PHENYL-6-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|(S)-5-PHENYL-6-(4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)-N-((TETRAHYDROFURAN-2-YL)METHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204585	-	PUBCHEM	11677453	C29H32N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YSWLNXFQMMFDFG-DEOSSOPVSA-N
29661	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9602	[4-[5-Phenyl-4-(2-piperazin-1-ylethylamino)furo[2,3-d]pyrimidin-6-yl]phenyl]-piperidin-1-ylmethanone	(4-(5-PHENYL-4-(2-(PIPERAZIN-1-YL)ETHYLAMINO)FURO[2,3-D]PYRIMIDIN-6-YL)PHENYL)(PIPERIDIN-1-YL)METHANONE|[4-[5-PHENYL-4-(2-PIPERAZIN-1-YLETHYLAMINO)FURO[2,3-D]PYRIMIDIN-6-YL]PHENYL]-PIPERIDIN-1-YLMETHANONE|BDBM50204584	-	PUBCHEM	11634876	C30H34N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SXBGVYYYZFBEKG-UHFFFAOYSA-N
29662	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9603	(4-Ethylpiperazin-1-yl)-[4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]phenyl]methanone	(4-ETHYLPIPERAZIN-1-YL)-[4-[4-[[(2S)-OXOLAN-2-YL]METHYLAMINO]-5-PHENYLFURO[2,3-D]PYRIMIDIN-6-YL]PHENYL]METHANONE|(S)-(4-ETHYLPIPERAZIN-1-YL)(4-(5-PHENYL-4-((TETRAHYDROFURAN-2-YL)METHYLAMINO)FURO[2,3-D]PYRIMIDIN-6-YL)PHENYL)METHANONE|BDBM50204583	-	PUBCHEM	11656437	C30H33N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FACSDOITOHWERB-DEOSSOPVSA-N
29663	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9604	5-Phenyl-N-(2-piperazin-1-ylethyl)-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]furo[2,3-d]pyrimidin-4-amine	5-PHENYL-N-(2-(PIPERAZIN-1-YL)ETHYL)-6-(4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|5-PHENYL-N-(2-PIPERAZIN-1-YLETHYL)-6-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204582	-	PUBCHEM	11684933	C30H36N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DMZTWOCJNVKCBW-UHFFFAOYSA-N
29664	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9605	5-Phenyl-N-(2-phenylethyl)-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]furo[2,3-d]pyrimidin-4-amine	Q27076548|COMPOUND 30 [PMID: 17280833]|GTPL8193|5-PHENYL-N-(2-PHENYLETHYL)-6-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|5-PHENYL-N-(2-PHENYLETHYL)-6-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]FURO[3,2-E]PYRIMIDIN-4-AMINE|N-PHENETHYL-5-PHENYL-6-(4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204580	-	PUBCHEM	11540659	C32H32N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CYXPHNZJEDAZDD-UHFFFAOYSA-N
29665	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9606	N-Isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)furo[2,3-d]pyrimidin-4-amine	N-ISOPROPYL-5-PHENYL-6-(4-(2-(PYRROLIDIN-1-YL)ETHOXY)PHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|5-PHENYL-N-PROPAN-2-YL-6-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204579	-	PUBCHEM	11626406	C27H30N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SSVDSZIWJBBCNN-UHFFFAOYSA-N
29666	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9607	6-(4-(Morpholinomethyl)phenyl)-5-phenyl-N-(2-(piperazin-1-yl)ethyl)furo[2,3-d]pyrimidin-4-amine	6-(4-(MORPHOLINOMETHYL)PHENYL)-5-PHENYL-N-(2-(PIPERAZIN-1-YL)ETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|6-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]-5-PHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204577	-	PUBCHEM	11620266	C29H34N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YKMSWECJITXGJA-UHFFFAOYSA-N
29667	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9608	6-(4-Morpholinophenyl)-5-phenyl-N-(2-(piperazin-1-yl)ethyl)furo[2,3-d]pyrimidin-4-amine	6-(4-MORPHOLIN-4-YLPHENYL)-5-PHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|6-(4-MORPHOLINOPHENYL)-5-PHENYL-N-(2-(PIPERAZIN-1-YL)ETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204576	-	PUBCHEM	11648745	C28H32N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YHTSUIXFAAQWLU-UHFFFAOYSA-N
29668	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	DiMauro EF (2007)	17280833	224894	9609	6-(4-Methyl-2,3-dihydro-1,4-benzoxazin-7-yl)-5-phenyl-N-(2-piperazin-1-ylethyl)furo[2,3-d]pyrimidin-4-amine	6-(4-METHYL-2,3-DIHYDRO-1,4-BENZOXAZIN-7-YL)-5-PHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|6-(4-METHYL-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-7-YL)-5-PHENYL-N-(2-(PIPERAZIN-1-YL)ETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE|BDBM50204575	-	PUBCHEM	11626947	C27H30N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SWTRMCZKDHCOOZ-UHFFFAOYSA-N
29669	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Martin MW (2007)	17276681	224895	9610	3-Phenyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-N-(2-pyridin-3-ylethyl)furo[2,3-b]pyridin-4-amine	3-PHENYL-2-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-N-(2-PYRIDIN-3-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE|3-PHENYL-2-{4-[2-(PIPERIDIN-1-YL)ETHOXY]PHENYL}-N-[2-(PYRIDIN-3-YL)ETHYL]FURO[2,3-B]PYRIDIN-4-AMINE|2,3-DIARYLFURO[2,3-B]PYRIDINE-4-AMINE, 19|BDBM17723	-	PUBCHEM	11519208	C33H34N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKKHXTGUTLRIAS-UHFFFAOYSA-N
29670	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Martin MW (2007)	17276681	224895	9611	2-[4-(2-Imidazol-1-ylethoxy)phenyl]-3-phenyl-N-(2-piperazin-1-ylethyl)furo[2,3-b]pyridin-4-amine	2-{4-[2-(1H-IMIDAZOL-1-YL)ETHOXY]PHENYL}-3-PHENYL-N-[2-(PIPERAZIN-1-YL)ETHYL]FURO[2,3-B]PYRIDIN-4-AMINE|2,3-DIARYLFURO[2,3-B]PYRIDINE-4-AMINE, 15|2-[4-(2-IMIDAZOL-1-YLETHOXY)PHENYL]-3-PHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE|BDBM17719	-	PUBCHEM	11613133	C30H32N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WYNDNQIGGGWABE-UHFFFAOYSA-N
29671	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9612	3-[4-[(3R)-3-(4-Ethyl-2-pyridin-3-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid	3-(4-((R)-3-(4-ETHYL-2-(PYRIDIN-3-YL)PHENOXY)BUTOXY)-2-METHYLPHENYL)PROPANOIC ACID|BDBM50199783	-	PUBCHEM	44439626	C27H31NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QNTSQSFJMIOVQR-HXUWFJFHSA-N
29672	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9613	3-[2-Ethyl-4-[(3R)-3-[2-pyridin-2-yl-4-(trifluoromethyl)phenoxy]butoxy]phenyl]propanoic acid	3-(2-ETHYL-4-((R)-3-(2-(PYRIDIN-2-YL)-4-(TRIFLUOROMETHYL)PHENOXY)BUTOXY)PHENYL)PROPANOIC ACID|BDBM50199781	-	PUBCHEM	11409173	C27H28F3NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JUWZDSPINIDMLW-GOSISDBHSA-N
29673	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9614	3-[4-[(3R)-3-(4-Ethyl-2-pyridin-2-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid	3-(4-((R)-3-(4-ETHYL-2-(PYRIDIN-2-YL)PHENOXY)BUTOXY)-2-METHYLPHENYL)PROPANOIC ACID|BDBM50199779	-	PUBCHEM	11178006	C27H31NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KZAXXZUCCUNGNL-HXUWFJFHSA-N
29674	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9615	3-[2-Methyl-4-[(3R)-3-[2-pyridin-2-yl-4-(trifluoromethyl)phenoxy]butoxy]phenyl]propanoic acid	3-(2-METHYL-4-((R)-3-(2-(PYRIDIN-2-YL)-4-(TRIFLUOROMETHYL)PHENOXY)BUTOXY)PHENYL)PROPANOIC ACID|BDBM50199777	-	PUBCHEM	44439633	C26H26F3NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AIUXBXGPPYWHFP-GOSISDBHSA-N
29675	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9616	3-[2-Ethyl-4-[(3R)-3-(4-ethyl-2-pyridin-2-ylphenoxy)butoxy]phenyl]propanoic acid	3-(2-ETHYL-4-((R)-3-(4-ETHYL-2-(PYRIDIN-2-YL)PHENOXY)BUTOXY)PHENYL)PROPANOIC ACID|BDBM50199776	-	PUBCHEM	11155087	C28H33NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GYZNATQOXOBZSD-HXUWFJFHSA-N
29676	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9617	3-[4-[(3R)-3-(4-Chloro-2-pyridin-2-ylphenoxy)butoxy]-2-methylphenyl]propanoic acid	3-(4-((R)-3-(4-CHLORO-2-(PYRIDIN-2-YL)PHENOXY)BUTOXY)-2-METHYLPHENYL)PROPANOIC ACID|BDBM50199773	-	PUBCHEM	11247654	C25H26ClNO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PHVHNSMKCROBSA-GOSISDBHSA-N
29677	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	9618	(R)-3-(4-(3-(2-Benzoyl-4-ethylphenoxy)butoxy)-2-methylphenyl)propanoic acid	(R)-3-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-BUTOXY]2-METHYL-PHENYL}PROPIONIC ACID|(R)-3-(4-(3-(2-BENZOYL-4-ETHYLPHENOXY)BUTOXY)-2-METHYLPHENYL)PROPANOIC ACID|BDBM50194627	-	PUBCHEM	11431103	C29H32O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ONHBOWNRMGRYNP-OAQYLSRUSA-N
29678	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Gonzalez IC (2007)	17129725	224896	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29679	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Trotter BW (2006)	17125248	224897	9619	3-Cyano-N-(2-hydroxyethyl)-6-methoxy-4-phenylisoquinoline-1-carboxamide	LS-193154|3-CYANO-N-(2-HYDROXYETHYL)-6-METHOXY-4-PHENYLISOQUINOLINE-1-CARBOXAMIDE|BDBM50199068	-	PUBCHEM	11995422	C20H17N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HFSNQOXBPWZLHD-UHFFFAOYSA-N
29680	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Jackson CM (2007)	17095219	224898	9620	2-(3,4-Dimethylphenyl)-3-[(4-methoxyphenyl)methoxy]-1,3-thiazolidin-4-one	DTXSID70658810|CTK3H0749|2-(3,4-DIMETHYLPHENYL)-3-(4-METHOXYBENZYLOXY)THIAZOLIDIN-4-ONE|4-THIAZOLIDINONE, 2-(3,4-DIMETHYLPHENYL)-3-[(4-METHOXYPHENYL)METHOXY]-|921611-08-7|2-(3,4-DIMETHYLPHENYL)-3-[(4-METHOXYPHENYL)METHOXY]-1,3-THIAZOLIDIN-4-ONE|BDBM50198249	-	PUBCHEM	44418119	C19H21NO3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NROGBECHHOOJMM-UHFFFAOYSA-N
29681	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Jackson CM (2007)	17095219	224898	9621	2-(3,4-Dimethylphenyl)-3-(4-methoxyphenethyl)-2-methylthiazolidin-4-one	2-(3,4-DIMETHYLPHENYL)-3-(4-METHOXYPHENETHYL)-2-METHYLTHIAZOLIDIN-4-ONE|BDBM50198247	-	PUBCHEM	44418146	C21H25NO2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JZFNWTIJEGVREY-UHFFFAOYSA-N
29682	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9622	3-[4-[2-[5-Methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy]-2-[(pyrazin-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-{4-[2-(2-BIPHENYL-4-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-2-[(PYRAZIN-2-YLOXYCARBONYLAMINO)-METHYL]-PHENYL}-PROPIONIC ACID|BDBM50195716	-	PUBCHEM	44420485	C33H30N4O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VATCVNIKAWMLQK-UHFFFAOYSA-N
29683	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9623	3-[4-[2-[5-Methyl-2-(4-phenoxyphenyl)-1,3-oxazol-4-yl]ethoxy]-2-[(propan-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-[4-[2-[5-METHYL-2-(4-PHENOXYPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|3-(2-((ISOPROPOXYCARBONYL)METHYL)-4-(2-(5-METHYL-2-(4-PHENOXYPHENYL)OXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|BDBM50195715	-	PUBCHEM	10144243	C32H34N2O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAINKGNWZLMMRF-UHFFFAOYSA-N
29684	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9624	3-(2-((Isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid	3-(2-((ISOPROPOXYCARBONYL)METHYL)-4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|BDBM50195714	-	PUBCHEM	10205220	C26H30N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QDTHAXJGRDPCSZ-UHFFFAOYSA-N
29685	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9625	3-[4-[2-[5-Methyl-2-(4-pyrimidin-2-ylphenyl)-1,3-oxazol-4-yl]ethoxy]-2-[(propan-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-(2-((ISOPROPOXYCARBONYL)METHYL)-4-(2-(5-METHYL-2-(4-(PYRIMIDIN-2-YL)PHENYL)OXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|3-[4-[2-[5-METHYL-2-(4-PYRIMIDIN-2-YLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|BDBM50195713	-	PUBCHEM	10119824	C30H32N4O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NTXHMSZOGJFPTJ-UHFFFAOYSA-N
29686	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9626	3-[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-[(pyrazin-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-(4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)-2-(((PYRAZIN-2-YLOXY)CARBONYL)METHYL)PHENYL)PROPANOIC ACID|BDBM50195711	-	PUBCHEM	44420506	C27H26N4O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CASKZOPCCIBBBW-UHFFFAOYSA-N
29687	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9627	3-(2-((Benzyloxycarbonyl)methyl)-4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid	3-(2-((BENZYLOXYCARBONYL)METHYL)-4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]-2-(PHENYLMETHOXYCARBONYLAMINOMETHYL)PHENYL]PROPANOIC ACID|BDBM50195710	-	PUBCHEM	17984540	C30H30N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FUTRFISBYXLQDO-UHFFFAOYSA-N
29688	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9628	3-[4-[2-(5-Methyl-2-morpholin-4-yl-1,3-thiazol-4-yl)ethoxy]-2-[(propan-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-(2-((ISOPROPOXYCARBONYL)METHYL)-4-(2-(5-METHYL-2-MORPHOLINOTHIAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|3-[4-[2-(5-METHYL-2-MORPHOLIN-4-YL-1,3-THIAZOL-4-YL)ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|3-{2-(ISOPROPOXYCARBONYLAMINOMETHYL)-4-[2-(5-METHYL-2-MORPHOLIN-4-YL-THIAZOL-4-YL)ETHOXY]-PHENYL}PROPIONIC ACID|BDBM50195708	-	PUBCHEM	9805639	C24H33N3O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IACIAFCVQNZHDL-UHFFFAOYSA-N
29689	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9629	3-[2-[(Benzylsulfonylamino)methyl]-4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]propanoic acid	3-(4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)-2-((PHENYLMETHYLSULFONAMIDO)METHYL)PHENYL)PROPANOIC ACID|BDBM50195707	-	PUBCHEM	44420484	C29H30N2O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AFMUUVLVLJLAEP-UHFFFAOYSA-N
29690	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	9630	3-[4-[2-[5-Methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy]-2-[(propan-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-[4-[2-[5-METHYL-2-(4-PHENYLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|3-[4-[2-(2-BIPHENYL-4-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-2-(ISOPROPOXYCARBONYLAMINO-METHYL)-PHENYL]-PROPIONIC ACID|BDBM50195702	-	PUBCHEM	10143678	C32H34N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLZAMMQCUXFOTM-UHFFFAOYSA-N
29691	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Warshawsky AM (2006)	17005394	224899	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29692	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9631	3-[5-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-propoxycarbonyl-3,4-dihydro-1H-isoquinolin-8-yl]propanoic acid	3-[5-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]-2-PROPOXYCARBONYL-3,4-DIHYDRO-1H-ISOQUINOLIN-8-YL]PROPANOIC ACID|3-(5-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)-2-(PROPOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-8-YL)PROPANOIC ACID|BDBM50195706	-	PUBCHEM	11317867	C28H32N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WVKGGZXCUUYLIT-UHFFFAOYSA-N
29693	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9632	3-[2-(2,2-Dimethylpropoxycarbonyl)-5-[2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy]-3,4-dihydro-1H-isoquinolin-8-yl]propanoic acid	3-[2-(2,2-DIMETHYLPROPOXYCARBONYL)-5-[2-[5-METHYL-2-(4-PHENYLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-3,4-DIHYDRO-1H-ISOQUINOLIN-8-YL]PROPANOIC ACID|5-[2-(2-BIPHENYL-4-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-8-(2-CARBOXY-ETHYL)-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID 2,2-DIMETHYL-PROPYL ESTER|BDBM50195705	-	PUBCHEM	44420402	C36H40N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JYMSZNJYYIGFPC-UHFFFAOYSA-N
29694	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9633	3-[5-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-(2-methylpropoxycarbonyl)-3,4-dihydro-1H-isoquinolin-8-yl]propanoic acid	3-(2-(ISOBUTOXYCARBONYL)-5-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)-1,2,3,4-TETRAHYDROISOQUINOLIN-8-YL)PROPANOIC ACID|3-[5-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]-2-(2-METHYLPROPOXYCARBONYL)-3,4-DIHYDRO-1H-ISOQUINOLIN-8-YL]PROPANOIC ACID|BDBM50195704	-	PUBCHEM	44420566	C29H34N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZGYKSGFEFIEJCW-UHFFFAOYSA-N
29695	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9634	3-[5-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-prop-2-ynoxycarbonyl-3,4-dihydro-1H-isoquinolin-8-yl]propanoic acid	3-(5-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)-2-((PROP-2-YNYLOXY)CARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-8-YL)PROPANOIC ACID|3-[5-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]-2-PROP-2-YNOXYCARBONYL-3,4-DIHYDRO-1H-ISOQUINOLIN-8-YL]PROPANOIC ACID|BDBM50195703	-	PUBCHEM	44420565	C28H28N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KZTWWKBUXGHLOG-UHFFFAOYSA-N
29696	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9630	3-[4-[2-[5-Methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy]-2-[(propan-2-yloxycarbonylamino)methyl]phenyl]propanoic acid	3-[4-[2-[5-METHYL-2-(4-PHENYLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-2-[(PROPAN-2-YLOXYCARBONYLAMINO)METHYL]PHENYL]PROPANOIC ACID|3-[4-[2-(2-BIPHENYL-4-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-2-(ISOPROPOXYCARBONYLAMINO-METHYL)-PHENYL]-PROPIONIC ACID|BDBM50195702	-	PUBCHEM	10143678	C32H34N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLZAMMQCUXFOTM-UHFFFAOYSA-N
29697	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9635	3-[5-[2-[5-Methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy]-2-propoxycarbonyl-3,4-dihydro-1H-isoquinolin-8-yl]propanoic acid	5-[2-(2-BIPHENYL-4-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-8-(2-CARBOXY-ETHYL)-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID PROPYL ESTER|3-[5-[2-[5-METHYL-2-(4-PHENYLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]-2-PROPOXYCARBONYL-3,4-DIHYDRO-1H-ISOQUINOLIN-8-YL]PROPANOIC ACID|BDBM50195699	-	PUBCHEM	11421714	C34H36N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LLUZQFNWHGWRKI-UHFFFAOYSA-N
29698	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	9636	Farglitazar	GTPL2672|O-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHYL]-N-[2-(PHENYLCARBONYL)PHENYL]-L-TYROSINE|2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID(GI 262570)|(S)-2-(2-BENZOYLPHENYLAMINO)-3-(4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|GI262570; FARGLITAZAR|FARGLITAZAR (USAN/INN)|KBIOSS_002350|L-TYROSINE, N-(2-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)|KBIOGR_002347|3433GY7132|DSSTOX_CID_27310|L-TYROSINE, N-(2-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-|D04132|KBIO2_007483|1FM9|DTXSID1047310|UNII-3433GY7132|NCGC00254050-01|FARGLITAZAR [USAN]|DSSTOX_GSID_47310|TOX21_300218|NCGC00247940-01|(S)-2-((2-BENZOYLPHENYL)AMINO)-3-(4-(2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY)PHENYL)PROPANOIC ACID|LS-184758|2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID|GI262570X|GI-262570|FARGLITAZAR|GI-262570X|FARGLITAZAR [USAN:INN]|196808-45-4|DSSTOX_RID_82260|CMAP_000025|2(S)-(2-BENZOYLPHENYLAMINO)-3-[4-[2-(5-METHYL-2-PHENYLOXAZOL-4-YL)ETHOXY]PHENYL]PROPIONIC ACID|(2S)-2-[[2-(BENZOYL)PHENYL]AMINO]-3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]PROPANOIC ACID|Q5435087|G1-262570|L-TYROSINE, N-(2-BENZOYLPHENYL)-O-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]- (9CI)|GI262570|GI 262570|KBIO2_002347|(S)-2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID|L-TYROSINE, N-(2-BENZOYLPHENYL)-O-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL]-|GI 262570X|ZINC49639808|N-(O-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-L-TYROSINE|KBIO2_004915|BDBM50085044	-	PUBCHEM	170364	C34H30N2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZZCHHVUQYRMYLW-HKBQPEDESA-N
29699	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henry JR (2006)	17005393	224900	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29700	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2006)	16987657	224901	9637	(2S)-N'-Hydroxy-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-N-[2-(2-phenyl-1H-indol-3-yl)ethyl]octanediamide	(S)-N8-HYDROXY-2-(2-(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETAMIDO)-N1-(2-(2-PHENYL-1H-INDOL-3-YL)ETHYL)OCTANEDIAMIDE|(2S)-N'-HYDROXY-2-[[2-(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETYL]AMINO]-N-[2-(2-PHENYL-1H-INDOL-3-YL)ETHYL]OCTANEDIAMIDE|BDBM50195108	-	PUBCHEM	11664499	C36H41N5O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VBWCMILVHANAGG-YTTGMZPUSA-N
29701	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2006)	16987657	224901	9638	N-[(2S)-1,8-Dioxo-1-[(4-phenyl-1,3-thiazol-2-yl)amino]nonan-2-yl]-1-methylpiperidine-2-carboxamide	(2S)-2-[(1-METHYLPIPERIDIN-2-YL)FORMAMIDO]-8-OXO-N-(4-PHENYL-1,3-THIAZOL-2-YL)NONANAMIDE|N-[(2S)-1,8-DIOXO-1-[(4-PHENYL-1,3-THIAZOL-2-YL)AMINO]NONAN-2-YL]-1-METHYLPIPERIDINE-2-CARBOXAMIDE|BIS-AMIDE INHIBITOR, 15|BDBM25144	-	PUBCHEM	16036765	C25H34N4O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MVGAXXKEFDOLGL-AIBWNMTMSA-N
29702	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9639	3-{4-[3-(2-Benzoyl-4-ethyl-phenoxy)-pentyloxy]-2-methyl-phenyl}-propionic acid	3-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-PENTYLOXY]-2-METHYL-PHENYL}-PROPIONIC ACID|3-[4-[3-(2-BENZOYL-4-ETHYLPHENOXY)PENTOXY]-2-METHYLPHENYL]PROPANOIC ACID|BDBM50194638	-	PUBCHEM	16085984	C30H34O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KEUWMDZMXVQKJB-UHFFFAOYSA-N
29703	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9640	(r)-3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-butoxy]-2-fluoro-phenyl}-propionic acid	3-[4-[(3R)-3-(4-CHLORO-2-PHENOXYPHENOXY)BUTOXY]-2-FLUOROPHENYL]PROPANOIC ACID|(R)-3-{4-[3-(4-CHLORO-2-PHENOXY-PHENOXY)-BUTOXY]-2-FLUORO-PHENYL}-PROPIONIC ACID|BDBM50194637	-	PUBCHEM	16085987	C25H24ClFO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WXCQOBJBCVSXBR-QGZVFWFLSA-N
29704	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9641	(R)-3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-butoxy]-2-methyl-phenyl}-propionic acid	(R)-3-{4-[3-(4-CHLORO-2-PHENOXY-PHENOXY)-BUTOXY]-2-METHYL-PHENYL}-PROPIONIC ACID|3-[4-[(3R)-3-(4-CHLORO-2-PHENOXYPHENOXY)BUTOXY]-2-METHYLPHENYL]PROPANOIC ACID|BDBM50194635	-	PUBCHEM	16085985	C26H27ClO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZARBOTMPCCXOHE-LJQANCHMSA-N
29705	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9642	3-{4-[3-(2-Benzoyl-4-ethyl-phenoxy)-butoxy]-2-methyl-phenyl}-propionic acid	LS-193043|3-[4-[3-(2-BENZOYL-4-ETHYLPHENOXY)BUTOXY]-2-METHYLPHENYL]PROPANOIC ACID|3-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-BUTOXY]-2-METHYL-PHENYL}-PROPIONIC ACID|3-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-BUTOXY]2-METHYL-PHENYL}PROPIONIC ACID|BDBM50194634	-	PUBCHEM	11305717	C29H32O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ONHBOWNRMGRYNP-UHFFFAOYSA-N
29706	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9643	(R)-3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-butoxy]-2-trifluoromethyl-phenyl}-propionic acid	3-[4-[(3R)-3-(4-CHLORO-2-PHENOXYPHENOXY)BUTOXY]-2-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID|(R)-3-{4-[3-(4-CHLORO-2-PHENOXY-PHENOXY)-BUTOXY]-2-TRIFLUOROMETHYL-PHENYL}-PROPIONIC ACID|BDBM50194633	-	PUBCHEM	16085982	C26H24ClF3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HIOGFQCBUGMDNX-QGZVFWFLSA-N
29707	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9644	(R)-3-{4-[3-(4-Ethyl-2-phenoxy-phenoxy)-butoxy]-2-methyl-phenyl}-propionic acid	3-[4-[(3R)-3-(4-ETHYL-2-PHENOXYPHENOXY)BUTOXY]-2-METHYLPHENYL]PROPANOIC ACID|(R)-3-{4-[3-(4-ETHYL-2-PHENOXY-PHENOXY)-BUTOXY]-2-METHYL-PHENYL}-PROPIONIC ACID|BDBM50194631	-	PUBCHEM	16085980	C28H32O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VWGFBGMULZAECR-OAQYLSRUSA-N
29708	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9645	(R)-3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-butoxy]-2-ethyl-phenyl}-propionic acid	LS-193041|3-[4-[(3R)-3-(4-CHLORO-2-PHENOXYPHENOXY)BUTOXY]-2-ETHYLPHENYL]PROPANOIC ACID|(R)-3-{4-[3-(4-CHLORO-2-PHENOXY-PHENOXY)-BUTOXY]-2-ETHYL-PHENYL}-PROPIONIC ACID|BDBM50194630	-	PUBCHEM	16085988	C27H29ClO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CIPGEDLLCCHFDI-LJQANCHMSA-N
29709	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9646	2-{4-[3-(2-Benzoyl-4-ethyl-phenoxy)-butoxy]-phenoxy}-2-methyl-propionic acid	2-[4-[3-(2-BENZOYL-4-ETHYLPHENOXY)BUTOXY]PHENOXY]-2-METHYLPROPANOIC ACID|2-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-BUTOXY]-PHENOXY}-2-METHYL-PROPIONIC ACID|BDBM50194629	-	PUBCHEM	11340513	C29H32O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ILHLGCBMPLPUEJ-UHFFFAOYSA-N
29710	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9647	(R)-3-{2-Methyl-4-[3-(2-phenoxy-4-trifluoromethyl-phenoxy)-butoxy]-phenyl}-propionic acid	3-[2-METHYL-4-[(3R)-3-[2-PHENOXY-4-(TRIFLUOROMETHYL)PHENOXY]BUTOXY]PHENYL]PROPANOIC ACID|(R)-3-{2-METHYL-4-[3-(2-PHENOXY-4-TRIFLUOROMETHYL-PHENOXY)-BUTOXY]-PHENYL}-PROPIONIC ACID|BDBM50194628	-	PUBCHEM	16085986	C27H27F3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CDXOSGNAXOTFBO-LJQANCHMSA-N
29711	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9618	(R)-3-(4-(3-(2-Benzoyl-4-ethylphenoxy)butoxy)-2-methylphenyl)propanoic acid	(R)-3-{4-[3-(2-BENZOYL-4-ETHYL-PHENOXY)-BUTOXY]2-METHYL-PHENYL}PROPIONIC ACID|(R)-3-(4-(3-(2-BENZOYL-4-ETHYLPHENOXY)BUTOXY)-2-METHYLPHENYL)PROPANOIC ACID|BDBM50194627	-	PUBCHEM	11431103	C29H32O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ONHBOWNRMGRYNP-OAQYLSRUSA-N
29712	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9648	2-(4-(3-(2-Benzoyl-4-ethylphenoxy)propoxy)phenoxy)-2-methylpropanoic acid	2-(4-(3-(2-BENZOYL-4-ETHYLPHENOXY)PROPOXY)PHENOXY)-2-METHYLPROPANOIC ACID|BDBM50194626	-	PUBCHEM	16085983	C28H30O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AFQIAKAIRKBLKC-UHFFFAOYSA-N
29713	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9649	(R)-3-{2-Methyl-4-[3-(2-phenoxy-4-trifluoromethoxy-phenoxy)-butoxy]-phenyl}-propionic acid	(R)-3-{2-METHYL-4-[3-(2-PHENOXY-4-TRIFLUOROMETHOXY-PHENOXY)-BUTOXY]-PHENYL}-PROPIONIC ACID|3-[2-METHYL-4-[(3R)-3-[2-PHENOXY-4-(TRIFLUOROMETHOXY)PHENOXY]BUTOXY]PHENYL]PROPANOIC ACID|BDBM50194625	-	PUBCHEM	16085981	C27H27F3O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CQHWVRVOKKOIJC-LJQANCHMSA-N
29714	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	9650	3-{4-[3-(2-Benzyl-4-ethyl-phenoxy)-butoxy]-2-methyl-phenyl}-propionic acid	3-[4-[3-(2-BENZYL-4-ETHYLPHENOXY)BUTOXY]-2-METHYLPHENYL]PROPANOIC ACID|3-{4-[3-(2-BENZYL-4-ETHYL-PHENOXY)-BUTOXY]-2-METHYL-PHENYL}-PROPIONIC ACID|BDBM50194624	-	PUBCHEM	11316788	C29H34O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QRUJOOQWHBDHME-UHFFFAOYSA-N
29715	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2006)	16970391	224902	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29716	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Nanda KK (2006)	16949818	224903	9651	N,N-Diisopropyl-3-phenyl-4-(3-phenylpropanamido)-2-(pyridin-3-yl)butanamide	N,N-DIISOPROPYL-3-PHENYL-4-(3-PHENYLPROPANAMIDO)-2-(PYRIDIN-3-YL)BUTANAMIDE|3-PHENYL-4-(3-PHENYLPROPANOYLAMINO)-N,N-DI(PROPAN-2-YL)-2-PYRIDIN-3-YLBUTANAMIDE|BDBM50194549	-	PUBCHEM	16067971	C30H37N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SBVQSSIMWONYEL-UHFFFAOYSA-N
29717	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Nanda KK (2006)	16949818	224903	9652	4-(3-(2-Fluorophenyl)propanamido)-N,N-diisopropyl-3-phenyl-2-(pyridin-3-yl)butanamide	4-(3-(2-FLUOROPHENYL)PROPANAMIDO)-N,N-DIISOPROPYL-3-PHENYL-2-(PYRIDIN-3-YL)BUTANAMIDE|4-[3-(2-FLUOROPHENYL)PROPANOYLAMINO]-3-PHENYL-N,N-DI(PROPAN-2-YL)-2-PYRIDIN-3-YLBUTANAMIDE|BDBM50194539	-	PUBCHEM	16067972	C30H36FN3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CFODJXSQXWCMFC-UHFFFAOYSA-N
29718	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Nanda KK (2006)	16949818	224903	9653	N,N-Diisopropyl-3-phenyl-4-(3-phenylbutanamido)-2-(pyridin-3-yl)butanamide	N,N-DIISOPROPYL-3-PHENYL-4-(3-PHENYLBUTANAMIDO)-2-(PYRIDIN-3-YL)BUTANAMIDE|3-PHENYL-4-(3-PHENYLBUTANOYLAMINO)-N,N-DI(PROPAN-2-YL)-2-PYRIDIN-3-YLBUTANAMIDE|BDBM50194512	-	PUBCHEM	16067973	C31H39N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MYRMFKGJHYHGEX-UHFFFAOYSA-N
29719	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Fluxe A (2006)	16942878	224904	9654	[(E)-(2,3-Diethyl-1-methyl-6,7-dihydro-5H-indol-4-ylidene)amino] N-phenylcarbamate	(E)-THYL-1-METHYL-6,7-DIHYDRO-1H-INDOL-4(5H)-ONE O-PHENYLCARBAMOYL OXIME|BDBM50194360	-	PUBCHEM	16049818	C20H25N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IPBYCCUTXNVVAE-CJLVFECKSA-N
29720	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Fluxe A (2006)	16942878	224904	9655	[(E)-(3-Ethyl-2-methyl-1,5,6,7-tetrahydroindol-4-ylidene)amino] N-phenylcarbamate	(E)--2-METHYL-6,7-DIHYDRO-1H-INDOL-4(5H)-ONE O-PHENYLCARBAMOYL OXIME|BDBM50194358	-	PUBCHEM	135401985	C18H21N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NATLTWZVCBHRJN-LTGZKZEYSA-N
29721	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9656	1-(3-(Trifluoromethyl)benzyl)-N-(naphthalen-2-ylsulfonyl)-1H-indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-N-(NAPHTHALEN-2-YLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193752	-	PUBCHEM	44419355	C27H19F3N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RSDUQVSYQVYCFK-UHFFFAOYSA-N
29722	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9657	3-(4-Methoxyphenyl)-N-(2-methylphenyl)sulfonyl-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-3-(4-METHOXYPHENYL)-N-(O-TOLYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193751	-	PUBCHEM	44419391	C31H25F3N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GIJPWVGTDPKGSQ-UHFFFAOYSA-N
29723	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9658	1-(3-(Trifluoromethyl)benzyl)-N-(3-(trifluoromethyl)phenylsulfonyl)-1H-indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-N-(3-(TRIFLUOROMETHYL)PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193750	-	PUBCHEM	44419352	C24H16F6N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BNRJBWWXERRJDS-UHFFFAOYSA-N
29724	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9659	3-(4-Methoxyphenyl)-N-(Phenylsulfonyl)-1-[3-(Trifluoromethyl)benzyl]-1h-Indole-2-Carboxamide	76023-EP2308860A1|3-(4-METHOXYPHENYL)-N-(PHENYLSULFONYL)-1-[3-(TRIFLUOROMETHYL)BENZYL]-1H-INDOLE-2-CARBOXAMIDE|N-(BENZENESULFONYL)-3-(4-METHOXYPHENYL)-1-[[3-(TRIFLUOROMETHYL)PHENYL]METHYL]INDOLE-2-CARBOXAMIDE|2HFP|1-(3-(TRIFLUOROMETHYL)BENZYL)-3-(4-METHOXYPHENYL)-N-(PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|Q27463924|(3-(4-METHOXYPHENYL)-1-{[3-(TRIFLUOROMETHYL)PHENYL]METHYL}INDOL-2-YL)-N-(PHENYLSULFONYL) CARBOXAMIDE|NSI|BDBM50193748	-	PUBCHEM	9549238	C30H23F3N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCPFCXDCWUXOGT-UHFFFAOYSA-N
29725	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9660	N-(4-Fluorophenyl)sulfonyl-3-(4-methoxyphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-N-(4-FLUOROPHENYLSULFONYL)-3-(4-METHOXYPHENYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193744	-	PUBCHEM	44419390	C30H22F4N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AOVDRHLXGSLJQB-UHFFFAOYSA-N
29726	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9661	1-(3-(Trifluoromethyl)benzyl)-N-(2-(trifluoromethyl)phenylsulfonyl)-1H-indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-N-(2-(TRIFLUOROMETHYL)PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193742	-	PUBCHEM	44419356	C24H16F6N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RYZBTWSMNGDKFD-UHFFFAOYSA-N
29727	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9662	1-(3-(Trifluoromethoxy)benzyl)-N-(3-(trifluoromethyl)phenylsulfonyl)-1H-indole-2-carboxamide	1-(3-(TRIFLUOROMETHOXY)BENZYL)-N-(3-(TRIFLUOROMETHYL)PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193741	-	PUBCHEM	44419366	C24H16F6N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MVMATXNFISADDB-UHFFFAOYSA-N
29728	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9663	N-(5-Chlorothiophen-2-yl)sulfonyl-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-N-(5-CHLOROTHIOPHEN-2-YLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193739	-	PUBCHEM	44419357	C21H14ClF3N2O3S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZRPUUOXOGLOCQT-UHFFFAOYSA-N
29729	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9664	3-(4-Methoxyphenyl)-N-methylsulfonyl-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-3-(4-METHOXYPHENYL)-N-(METHYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193736	-	PUBCHEM	44419392	C25H21F3N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RUSDVKUNFXBCHZ-UHFFFAOYSA-N
29730	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9665	Methyl 2-[[3-(4-methoxyphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carbonyl]sulfamoyl]benzoate	2-{[3-(4-METHOXY-PHENYL)-1-(3-TRIFLUOROMETHYL-BENZYL)-1H-INDOLE-2-CARBONYL]-SULFAMOYL}-BENZOIC ACID METHYL ESTER|BDBM50193734	-	PUBCHEM	44419255	C32H25F3N2O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RRLTYQDNNRNQPH-UHFFFAOYSA-N
29731	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9666	1-(3-(Benzyloxy)benzyl)-N-(3-(trifluoromethyl)phenylsulfonyl)-1H-indole-2-carboxamide	1-(3-(BENZYLOXY)BENZYL)-N-(3-(TRIFLUOROMETHYL)PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193733	-	PUBCHEM	44419381	C30H23F3N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NZNRDAXVBYSQEB-UHFFFAOYSA-N
29732	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	9667	3-(4-Methoxyphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]-N-[3-(trifluoromethyl)phenyl]sulfonylindole-2-carboxamide	1-(3-(TRIFLUOROMETHYL)BENZYL)-3-(4-METHOXYPHENYL)-N-(3-(TRIFLUOROMETHYL)PHENYLSULFONYL)-1H-INDOLE-2-CARBOXAMIDE|BDBM50193729	-	PUBCHEM	44419253	C31H22F6N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LINUGMFIDAUGBH-UHFFFAOYSA-N
29733	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Hopkins CR (2006)	16919947	170617	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29734	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9668	Tert-butyl N-[(2S)-1-(cycloheptylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOHEPTYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|TERT-BUTYL N-[(2S)-1-(CYCLOHEPTYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|THIOLATE ANALOGUE, 18A|BDBM19136	-	PUBCHEM	11844893	C19H36N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTVMPAGMFUPGRI-INIZCTEOSA-N
29735	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9669	Tert-butyl N-[(2S)-1-(cyclohexylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOHEXYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|THIOLATE ANALOGUE, 17A|TERT-BUTYL N-[(2S)-1-(CYCLOHEXYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|BDBM19135	-	PUBCHEM	11844892	C18H34N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NREURQUIJSGJMZ-HNNXBMFYSA-N
29736	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9670	Tert-butyl N-[(2S)-1-(cyclopentylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOPENTYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|TERT-BUTYL N-[(2S)-1-(CYCLOPENTYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|THIOLATE ANALOGUE, 16A|BDBM19134	-	PUBCHEM	11844891	C17H32N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IKSFNOMXHPMYIQ-AWEZNQCLSA-N
29737	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29738	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9671	3-(1-((2-(3,5-Dimethylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid	3-[1-[[2-(3,5-DIMETHYLPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]-2-ETHOXYPROPANOIC ACID|RAC-3-{1-[2-(3,5-DIMETHYL-PHENYL)-5-METHYL-OXAZOL-4-YLMETHYL]-1H-INDOL-5-YL}-2-ETHOXY-PROPIONIC ACID|3-(1-((2-(3,5-DIMETHYLPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID|BDBM50188038	-	PUBCHEM	10455511	C26H28N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DSKLBNZCCNQVBC-UHFFFAOYSA-N
29739	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9672	3-(1-((2-(3,5-Dichlorophenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid	3-[1-[[2-(3,5-DICHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]-2-ETHOXYPROPANOIC ACID|RAC-3-{1-[2-(3,5-DICHLORO-PHENYL)-5-METHYL-OXAZOL-4-YLMETHYL]-1H-INDOL-5-YL}-2-ETHOXY-PROPIONIC ACID|3-(1-((2-(3,5-DICHLOROPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID|BDBM50188037	-	PUBCHEM	10344769	C24H22Cl2N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RQMKNZHMAWCBJL-UHFFFAOYSA-N
29740	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9673	3-(1-((2-(3-Chlorophenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid	3-(1-((2-(3-CHLOROPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID|3-[1-[[2-(3-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]-2-ETHOXYPROPANOIC ACID|RAC-3-{1-[2-(3-CHLORO-PHENYL)-5-METHYL-OXAZOL-4-YLMETHYL]-1H-INDOL-5-YL}-2-ETHOXY-PROPIONIC ACID|BDBM50188035	-	PUBCHEM	9980586	C24H23ClN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HMMQETYZLNQVSF-UHFFFAOYSA-N
29741	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9674	3-(1-((2-(3,5-Dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid	3-[1-[[2-(3,5-DIMETHOXYPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]-2-ETHOXYPROPANOIC ACID|RAC-3-{1-[2-(3,5-DIMETHOXY-PHENYL)-5-METHYL-OXAZOL-4-YLMETHYL]-1H-INDOL-5-YL}-2-ETHOXY-PROPIONIC ACID|3-(1-((2-(3,5-DIMETHOXYPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID|BDBM50188025	-	PUBCHEM	10412116	C26H28N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PMZZWDLQGMUYFU-UHFFFAOYSA-N
29742	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9675	3-(1-((2-(4-Tert-butylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid	3-(1-((2-(4-TERT-BUTYLPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID|3-[1-[[2-(4-TERT-BUTYLPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]-2-ETHOXYPROPANOIC ACID|BDBM50188024	-	PUBCHEM	10072967	C28H32N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FVPCEABQEUPZJE-UHFFFAOYSA-N
29743	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9676	2-Ethoxy-3-(1-((2-(4-isopropylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid	2-ETHOXY-3-[1-[[5-METHYL-2-(4-PROPAN-2-YLPHENYL)-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]PROPANOIC ACID|2-ETHOXY-3-(1-((2-(4-ISOPROPYLPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)PROPANOIC ACID|BDBM50188023	-	PUBCHEM	10343538	C27H30N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UDXHXODNGSKQKU-UHFFFAOYSA-N
29744	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Kuhn B (2006)	16737814	224906	9677	2-Ethoxy-3-(1-((2-(4-ethylphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid	RAC-2-ETHOXY-3-{1-[2-(4-ETHYL-PHENYL)-5-METHYL-OXAZOL-4-YLMETHYL]-1H-INDOL-5-YL}-PROPIONIC ACID|2-ETHOXY-3-[1-[[2-(4-ETHYLPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL]INDOL-5-YL]PROPANOIC ACID|2-ETHOXY-3-(1-((2-(4-ETHYLPHENYL)-5-METHYLOXAZOL-4-YL)METHYL)-1H-INDOL-5-YL)PROPANOIC ACID|BDBM50188022	-	PUBCHEM	10342769	C26H28N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTXIDZKNOYTSIW-UHFFFAOYSA-N
29745	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Lu IL (2006)	16640330	171129	9678	N-[1-(4-Fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-YL]-3,5-bis(trifluoromethyl)benzenesulfonamide	N-(1-(4-FLUOROPHENYL)-3-(THIOPHEN-2-YL)-1H-PYRAZOL-5-YL)-3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONAMIDE|MCULE-9080417768|Q27465446|N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]-3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONAMIDE|N-[1-(4-FLUOROPHENYL)-3-THIOPHEN-2-YL-1H-PYRAZOL-5-YL]-3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONAMIDE|ZINC24800189|2G0H|BDBM50185944	-	PUBCHEM	2742759	C21H12F7N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BQSKQGGQDUBLNS-UHFFFAOYSA-N
29746	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9679	Ethyl (E,4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[(3-hydroxy-2-methylbenzoyl)amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]-6-methylhept-2-enoate	HMB-PHE-GLN-LEU-VE|BDBM50185159	-	PUBCHEM	44411546	C32H42N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VERCUUHDSDHZNE-HQSFGPFHSA-N
29747	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9680	Ethyl (E,4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-6-methylhept-2-enoate	H-TYR-VAL-GLN-LEU-VE|BDBM50185158	-	PUBCHEM	44411707	C29H45N5O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSGMPWLDSQFOIU-YLKYAQCOSA-N
29748	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9681	Ethyl (E,4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[(3-hydroxy-2-methylbenzoyl)amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-6-methylhept-2-enoate	HMB-VAL-GLN-LEU-VE|BDBM50185156	-	PUBCHEM	16084592	C28H42N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PWQJCQOSOVJZKC-KFMGUWMRSA-N
29749	111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	unknown	target	Marastoni M (2006)	16603348	224794	9682	Ethyl (E,4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-6-methylhept-2-enoate	H-PHE-VAL-GLN-LEU-VE|BDBM50185155	-	PUBCHEM	44411716	C29H45N5O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NTQHQJQYFBCDLD-BRYGMPRLSA-N
29750	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Mahindroo N (2006)	16451087	171122	4493	2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID	CAY10573|(5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACID|5-[3-(6-BENZOYL-1-PROPYL-2-NAPHTHYLOXY)PROPOXY]-1H-INDOLE-1-ACETIC ACID|Q27095435|1444AH|853652-40-1|5-[3-[(6-BENZOYL-1-PROPYL-2-NAPHTHALENYL)OXY]PROPOXY]-1H-INDOLE-1-ACETIC ACID|2F4B|2-(5-{3-[(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACID|ZINC12504466|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID|DB04689|2-(5-(3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY)-1H-INDOL-1-YL)ACETIC ACID|[5-(3-{[6-(PHENYLCARBONYL)-1-PROPYLNAPHTHALEN-2-YL]OXY}PROPOXY)-1H-INDOL-1-YL]ACETIC ACID|NS00070789|BDBM50181911	-	DRUGBANK	DB04689	C33H31NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZXWVCCFKIRBLDP-UHFFFAOYSA-N
29751	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Mahindroo N (2006)	16451087	171122	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29752	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Mahindroo N (2005)	16366601	224907	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29753	110474	4331	-	MNAT1	CAP35|MAT1|RNF66|TFB3	9606	Homo sapiens	unknown	target	Caligiuri M (2005)	16242653	66939	9683	Cdk/Crk Inhibitor	PYRAZOLOPYRIMIDONE ANALOG, RGB-286147|NCGC00345809-02|K00600A|GTPL5943|784211-09-2|BCP29074|1-(2,6-DICHLOROPHENYL)-6-[[4-(2-HYDROXYETHOXY)PHENYL]METHYL]-3-PROPAN-2-YL-2H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE|ZINC29056064|Q27075833|1-(2,6-DICHLOROPHENYL)-1,5-DIHYDRO-6-((4-(2-HYDROXYETHOXY)PHENYL)METHYL)-3-(1-METHYLETHYL)-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE|1-(2,6-DICHLOROPHENYL)-6-{[4-(2-HYDROXYETHOXY)PHENYL]METHYL}-3-(PROPAN-2-YL)-1H,2H,4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE|RGB-286147|A16795|HMS3229E20|CCG-206832|CTK8F1289|HMS3674M03|DTXSID60429556|CDK/CRK INHIBITOR|NCGC00345809-01|EX-229;EX 229;AMPK ACTIVATOR 991|BDBM59227	-	PUBCHEM	135473382	C23H22Cl2N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RSQPNXBTPUXMQN-UHFFFAOYSA-N
29754	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Morphy R (2005)	16220969	224908	9684	2-Methyl-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-phenoxy-propionic acid	2-METHYL-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PHENOXY-PROPIONIC ACID|2-METHYL-3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|BDBM50145712	-	PUBCHEM	10139247	C28H27NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSTSZHVRXHMZQK-UHFFFAOYSA-N
29755	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Shinji C (2005)	16137884	224909	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29756	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi GQ (2005)	15974597	170490	9685	(2S)-2-[(2-Oxo-3,5,7-tripropyl-1,3-benzoxazol-6-yl)oxy]-2-(4-propan-2-ylphenyl)acetic acid	I(S)-(4-ISOPROPYL-PHENYL)-(2-OXO-3,5,7-TRIPROPYL-2,3-DIHYDRO-BENZOOXAZOL-6-YLOXY)-ACETIC ACID|BDBM50169254	-	PUBCHEM	11247998	C27H35NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VGNJRUSCVGOQDZ-DEOSSOPVSA-N
29757	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi GQ (2005)	15974597	170490	9686	(S)-(4-Isopropyl-phenyl)-(4-propionyl-2,6-dipropyl-phenoxy)-acetic acid	(S)-(4-ISOPROPYL-PHENYL)-(4-PROPIONYL-2,6-DIPROPYL-PHENOXY)-ACETIC ACID|BDBM50169253	-	PUBCHEM	11223613	C26H34O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BLBKQSCECDPYAW-VWLOTQADSA-N
29758	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi GQ (2005)	15974597	170490	9687	(2S)-2-[(2-Oxo-3-propan-2-yl-5,7-dipropyl-1,3-benzoxazol-6-yl)oxy]-2-(4-propan-2-ylphenyl)acetic acid	(S)-(3-ISOPROPYL-2-OXO-5,7-DIPROPYL-2,3-DIHYDRO-BENZOOXAZOL-6-YLOXY)-(4-ISOPROPYL-PHENYL)-ACETIC ACID|BDBM50169245	-	PUBCHEM	11339979	C27H35NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CMBADTBQKXKEOM-DEOSSOPVSA-N
29759	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi GQ (2005)	15974597	170490	9688	(2S)-2-[(3-Methyl-2-oxo-5,7-dipropyl-1,3-benzoxazol-6-yl)oxy]-2-(4-propan-2-ylphenyl)acetic acid	(S)-(4-ISOPROPYL-PHENYL)-(3-METHYL-2-OXO-5,7-DIPROPYL-2,3-DIHYDRO-BENZOOXAZOL-6-YLOXY)-ACETIC ACID|BDBM50169233	-	PUBCHEM	11189474	C25H31NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VSBAWOCZJWUIIT-QFIPXVFZSA-N
29760	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Shi GQ (2005)	15974597	170490	9689	(S)-(3-Ethyl-2-oxo-5,7-dipropyl-2,3-dihydro-benzooxazol-6-yloxy)-(4-isopropyl-phenyl)-acetic acid	(S)-(3-ETHYL-2-OXO-5,7-DIPROPYL-2,3-DIHYDRO-BENZOOXAZOL-6-YLOXY)-(4-ISOPROPYL-PHENYL)-ACETIC ACID|BDBM50169227	-	PUBCHEM	11178156	C26H33NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WEQANHSKIULRFP-QHCPKHFHSA-N
29761	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9690	2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]acetonitrile	{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-ACETONITRILE|BDBM50166303	-	PUBCHEM	44400131	C27H21F3N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZAJIYHJMAFTGB-UHFFFAOYSA-N
29762	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9691	(2S)-2-[5-[1-(6-Chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]oxy-2-propylphenoxy]propanoic acid	(S)-2-{5-[1-(6-CHLORO-BENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-2-PROPYL-PHENOXY}-PROPIONIC ACID|BDBM50166302	-	PUBCHEM	44399972	C29H24ClF3N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NKVXQMXXQRJUBJ-INIZCTEOSA-N
29763	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9692	(4-Methoxyphenyl)-[2-methyl-3-[(3-prop-2-ynoxyphenyl)methyl]-5-(trifluoromethoxy)indol-1-yl]methanone	(4-METHOXY-PHENYL)-[2-METHYL-3-(3-PROP-2-YNYLOXY-BENZYL)-5-TRIFLUOROMETHOXY-INDOL-1-YL]-METHANONE|BDBM50166301	-	PUBCHEM	44399967	C28H22F3NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HEMWJRLDDQKGLA-UHFFFAOYSA-N
29764	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9693	(2S)-2-[2-Chloro-5-[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]oxyphenoxy]propanoic acid	(2S)-2-[2-CHLORO-5-[1-(6-CHLORO-1,2-BENZOXAZOL-3-YL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]OXYPHENOXY]PROPANOIC ACID|(S)-2-{2-CHLORO-5-[1-(6-CHLORO-BENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50166300	-	PUBCHEM	10371027	C26H17Cl2F3N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PESUMSRASMUYKX-ZDUSSCGKSA-N
29765	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9694	(2S)-2-[4-Chloro-3-[1-(6-chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]oxyphenoxy]propanoic acid	(S)-2-{4-CHLORO-3-[1-(6-CHLORO-BENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|(2S)-2-(4-CHLORO-3-(1-(6-CHLOROBENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YLOXY)PHENOXY)PROPANOIC ACID|(2S)-2-[4-CHLORO-3-[1-(6-CHLORO-1,2-BENZOXAZOL-3-YL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]OXYPHENOXY]PROPANOIC ACID|BDBM50166298	-	PUBCHEM	10438226	C26H17Cl2F3N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NOWYXMPKECMLMR-ZDUSSCGKSA-N
29766	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9695	(2S)-2-[3-[[1-(6-Methoxyquinolin-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(S)-2-{3-[1-(6-METHOXY-QUINOLIN-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50166296	-	PUBCHEM	44399773	C30H25F3N2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VBLJJBHFZCXXCW-SFHVURJKSA-N
29767	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9696	(2R)-2-[4-Chloro-3-[[1-(6-methoxy-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(R)-2-{4-CHLORO-3-[1-(6-METHOXY-BENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50166295	-	PUBCHEM	44399983	C28H22ClF3N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QRGIUBNDZNAVAU-OAHLLOKOSA-N
29768	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9697	(2S)-2-[3-[1-(6-Chloro-1,2-benzoxazol-3-yl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]oxyphenoxy]propanoic acid	(2S)-2-[3-[1-(6-CHLORO-1,2-BENZOXAZOL-3-YL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]OXYPHENOXY]PROPANOIC ACID|(S)-2-{3-[1-(6-CHLORO-BENZO[D]ISOXAZOL-3-YL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50166293	-	PUBCHEM	10437965	C26H18ClF3N2O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VGORCQXXKHIAFG-AWEZNQCLSA-N
29769	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9698	(2S)-2-[3-[[1-(4-Methoxyphenyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(S)-2-{3-[1-(4-METHOXY-PHENYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50166292	-	PUBCHEM	44399778	C27H24F3NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WASROFIOUZGJFW-KRWDZBQOSA-N
29770	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Liu K (2005)	15863293	224910	9699	(2S)-2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(2S)-2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3- YL]METHYL]PHENOXY]PROPANOIC ACID|Q27087738|(S)-2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|(2S)-2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|MRL24|(2S)-2-[3-({1-[(4-METHOXYPHENYL)CARBONYL]-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL}METHYL)PHENOXY]PROPANOIC ACID|GTPL6743|(S)-2-(3-((1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL)METHYL)PHENOXY)PROPANOIC ACID|NCGC00390369-01|(2S)-2-(3-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID|MRL 24|BDBM50157917	-	PUBCHEM	9958543	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OFCWBJAYEIROGZ-KRWDZBQOSA-N
29771	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	unknown	target	Fabian MA (2005)	15711537	224911	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29772	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	unknown	target	Fabian MA (2005)	15711537	224911	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29773	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9700	{4-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-ylmethyl]-phenoxy}-acetic acid	2-[4-[[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOL-3-YL]METHYL]PHENOXY]ACETIC ACID|{4-[1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YLMETHYL]-PHENOXY}-ACETIC ACID|BDBM50157938	-	PUBCHEM	10226701	C26H22ClNO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YAGQPGVXBAGTLQ-UHFFFAOYSA-N
29774	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9701	CID 10143056	Q27087737|(2S)-2-(2-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID|MRL20|(2S)-2-[2-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|GTPL6742|(2S)-2-[2-({1-[(4-METHOXYPHENYL)CARBONYL]-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL}METHYL)PHENOXY]PROPANOIC ACID|(S)-2-{2-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50157936	-	PUBCHEM	10143056	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWTOBMCYVACNJZ-KRWDZBQOSA-N
29775	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9702	2-{3-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-ylmethyl]-phenoxy}-propionic acid	2-{3-[1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|2-[3-[[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|BDBM50157934	-	PUBCHEM	10184159	C27H24ClNO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UZJIHIMYKLEBBQ-UHFFFAOYSA-N
29776	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9703	2-{2-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluoromethoxy-1H-indol-3-ylmethyl]-phenoxy}-propionic acid	2-{2-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|2-[2-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|BDBM50157933	-	PUBCHEM	10208548	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWTOBMCYVACNJZ-UHFFFAOYSA-N
29777	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9704	(2R)-2-[2-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(2R)-2-[2-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|(R)-2-{2-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50157932	-	PUBCHEM	10119125	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWTOBMCYVACNJZ-QGZVFWFLSA-N
29778	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9705	2-[2-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]-2-methylpropanoic acid	2-[2-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]-2-METHYLPROPANOIC ACID|2-{2-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID|BDBM50157931	-	PUBCHEM	10230642	C29H26F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SGUDWIZALUVLKT-UHFFFAOYSA-N
29779	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9706	2-{2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-ylmethyl]-phenoxy}-propionic acid	2-[2-[[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|2-{2-[1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50157930	-	PUBCHEM	10277333	C27H24ClNO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XICCHOADKSBRIM-UHFFFAOYSA-N
29780	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9707	(2R)-2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(2R)-2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|(R)-2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|BDBM50157927	-	PUBCHEM	44388966	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OFCWBJAYEIROGZ-QGZVFWFLSA-N
29781	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9708	2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluoromethoxy-1H-indol-3-ylmethyl]-phenoxy}-propionic acid	2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|BDBM50157926	-	PUBCHEM	10279905	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OFCWBJAYEIROGZ-UHFFFAOYSA-N
29782	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9709	2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]butanoic acid	2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-BUTYRIC ACID|BDBM50157925	-	PUBCHEM	44389085	C29H26F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XTHHGKZVXMNJNA-UHFFFAOYSA-N
29783	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9710	2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]pentanoic acid	2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PENTANOIC ACID|BDBM50157921	-	PUBCHEM	44389098	C30H28F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UNNWWBCMUJHNAH-UHFFFAOYSA-N
29784	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9711	2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]-2-methylpropanoic acid	2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]-2-METHYLPROPANOIC ACID|2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID|BDBM50157920	-	PUBCHEM	10280496	C29H26F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WTIUDROYDYCRCV-UHFFFAOYSA-N
29785	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9712	2-[2-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]butanoic acid	2-{2-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-BUTYRIC ACID|BDBM50157919	-	PUBCHEM	44388998	C29H26F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CHGUIFODGMMMKV-UHFFFAOYSA-N
29786	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9713	2-[2-[[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]methyl]phenoxy]-2-methylpropanoic acid	2-{2-[1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YLMETHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID|2-[2-[[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOL-3-YL]METHYL]PHENOXY]-2-METHYLPROPANOIC ACID|BDBM50157918	-	PUBCHEM	10184971	C28H26ClNO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HIPJZUFYVANNKA-UHFFFAOYSA-N
29787	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9699	(2S)-2-[3-[[1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid	(2S)-2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3- YL]METHYL]PHENOXY]PROPANOIC ACID|Q27087738|(S)-2-{3-[1-(4-METHOXY-BENZOYL)-2-METHYL-5-TRIFLUOROMETHOXY-1H-INDOL-3-YLMETHYL]-PHENOXY}-PROPIONIC ACID|(2S)-2-[3-[[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)INDOL-3-YL]METHYL]PHENOXY]PROPANOIC ACID|MRL24|(2S)-2-[3-({1-[(4-METHOXYPHENYL)CARBONYL]-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL}METHYL)PHENOXY]PROPANOIC ACID|GTPL6743|(S)-2-(3-((1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL)METHYL)PHENOXY)PROPANOIC ACID|NCGC00390369-01|(2S)-2-(3-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID|MRL 24|BDBM50157917	-	PUBCHEM	9958543	C28H24F3NO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OFCWBJAYEIROGZ-KRWDZBQOSA-N
29788	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Acton JJ (2005)	15603954	224912	9714	2-[3-[[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]methyl]phenoxy]-2-methylpropanoic acid	2-{3-[1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YLMETHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID|2-[3-[[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOL-3-YL]METHYL]PHENOXY]-2-METHYLPROPANOIC ACID|BDBM50157916	-	PUBCHEM	10228304	C28H26ClNO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NJQKVYQTUIWJEQ-UHFFFAOYSA-N
29789	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9715	(S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid	(2S)-2-METHOXY-3-[4-[3-(4-PHENYLPHENOXY)PROPOXY]PHENYL]PROPANOIC ACID|(S)-3-{4-[3-(BIPHENYL-4-YLOXY)-PROPOXY]-PHENYL}-2-METHOXY-PROPIONIC ACID|BDBM50157061	-	PUBCHEM	10223023	C25H26O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CFJFKSKRLAYDHM-DEOSSOPVSA-N
29790	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9716	(S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-ynyl]-phenyl}-propionic acid	(S)-2-METHOXY-3-{4-[4-(4-PHENOXY-PHENOXY)-BUT-1-YNYL]-PHENYL}-PROPIONIC ACID|(2S)-2-METHOXY-3-[4-[4-(4-PHENOXYPHENOXY)BUT-1-YNYL]PHENYL]PROPANOIC ACID|(2S)-2-METHOXY-3-{4-[4-(4-PHENOXY-PHENOXY)-BUT-1-YNYL]-PHENYL}-PROPIONIC ACID|BDBM50157060	-	PUBCHEM	10136660	C26H24O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PXPYSVWYMMGIEN-VWLOTQADSA-N
29791	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9717	(S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid	(2S)-3-[4-[3-(4-BENZOYLPHENOXY)PROPOXY]PHENYL]-2-METHOXYPROPANOIC ACID|(S)-3-{4-[3-(4-BENZOYL-PHENOXY)-PROPOXY]-PHENYL}-2-METHOXY-PROPIONIC ACID|BDBM50157059	-	PUBCHEM	10226233	C26H26O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ONPSUOOPYWPISK-DEOSSOPVSA-N
29792	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9718	(S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid	(2S)-2-METHOXY-3-[3-METHOXY-4-[3-(4-PHENOXYPHENOXY)PROPOXY]PHENYL]PROPANOIC ACID|(S)-2-METHOXY-3-{3-METHOXY-4-[3-(4-PHENOXY-PHENOXY)-PROPOXY]-PHENYL}-PROPIONIC ACID|BDBM50157058	-	PUBCHEM	10297760	C26H28O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IUORCUOWVWRBDQ-VWLOTQADSA-N
29793	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9719	(S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-ynyl]-phenyl}-propionic acid	(2S)-2-METHOXY-3-[4-[5-(4-PHENOXYPHENOXY)PENT-1-YNYL]PHENYL]PROPANOIC ACID|(S)-2-METHOXY-3-{4-[5-(4-PHENOXY-PHENOXY)-PENT-1-YNYL]-PHENYL}-PROPIONIC ACID|(2S)-2-METHOXY-3-{4-[5-(4-PHENOXY-PHENOXY)-PENT-1-YNYL]-PHENYL}-PROPIONIC ACID|BDBM50157057	-	PUBCHEM	10113515	C27H26O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KNNHPJKYTMZLEP-SANMLTNESA-N
29794	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9720	Naveglitazar	UNII-Y995M7GM0G|LY 519818|476436-68-7|LY-519818|HY-U00036A|(2S)-2-METHOXY-3-(4-(3-(4-PHENOXYPHENOXY)PROPOXY)PHENYL)PROPANOIC ACID|D08949|BENZENEPROPANOIC ACID, ALPHA-METHOXY-4-(3-(4-PHENOXYPHENOXY)PROPOXY)-, (ALPHAS)-|LY-818|ZINC3950327|CCRIS 9448|LY519818|(S)-2-METHOXY-3-{4-[3-(4-PHENOXY-PHENOXY)-PROPOXY]-PHENYL}-PROPIONIC ACID|Q27294403|NAVEGLITAZAR (USAN/INN)|(2S)-2-METHOXY-3-[4-[3-(4-PHENOXYPHENOXY)PROPOXY]PHENYL]PROPANOIC ACID|NAVEGLITAZAR [USAN:INN]|LY-9818|LY9818|LY 9818|CS-0021934|DB12662|NAVEGLITAZAR|Y995M7GM0G|BDBM50157056	-	PUBCHEM	9888484	C25H26O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OKJHGOPITGTTIM-DEOSSOPVSA-N
29795	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9721	(S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-phenyl}-2-methoxy-propionic acid	(2S)-3-[4-[3-(4-BENZOYLPHENOXY)PROPOXY]-3-CHLOROPHENYL]-2-METHOXYPROPANOIC ACID|(S)-3-{4-[3-(4-BENZOYL-PHENOXY)-PROPOXY]-3-CHLORO-PHENYL}-2-METHOXY-PROPIONIC ACID|BDBM50157055	-	PUBCHEM	44392315	C26H25ClO6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XCVUGMYZFJHTQE-DEOSSOPVSA-N
29796	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	9722	(S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-propionic acid	NAVAGLITAZAR|(S)-2-ETHOXY-3-{4-[3-(4-PHENOXY-PHENOXY)-PROPOXY]-PHENYL}-PROPIONIC ACID|BDBM50157054	-	PUBCHEM	10115344	C26H28O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QTVFGQWILVTOFS-VWLOTQADSA-N
29797	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Martin JA (2005)	15582409	224913	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29798	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jose B (2004)	15454224	224914	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29799	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9723	3-{4-[2-(2-Biphenyl-3-yl-5-methyl-oxazol-4-yl)ethoxy]-phenyl}-2-methyl-2-phenoxypropionic acid	3-{4-[2-(2-BIPHENYL-3-YL-5-METHYL-OXAZOL-4-YL)ETHOXY]-PHENYL}-2-METHYL-2-PHENOXYPROPIONIC ACID|3-{4-[2-(2-BIPHENYL-3-YL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-METHYL-2-PHENOXY-PROPIONIC ACID|2-METHYL-3-[4-[2-[5-METHYL-2-(3-PHENYLPHENYL)-1,3-OXAZOL-4-YL]ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|BDBM50145723	-	PUBCHEM	10119393	C34H31NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QUFDAJDYOPXGGD-UHFFFAOYSA-N
29800	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9724	(2S)-2-Methyl-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	(2S)-2-METHYL-3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|(S)-2-METHYL-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PHENOXY-PROPIONIC ACID|BDBM50145722	-	PUBCHEM	10004270	C28H27NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSTSZHVRXHMZQK-NDEPHWFRSA-N
29801	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9725	(2S)-2-Methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	Q27083197|(S)-2-METHYL-3-{4-[2-(5-METHYL-2-THIOPHEN-2-YL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PHENOXY-PROPIONIC ACID|LY-510929|(2S)-2-METHYL-3-[4-[2-(5-METHYL-2-THIOPHEN-2-YL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|LY-929|(2S)-2-METHYL-3-[4-[2-(5-METHYL-2-THIOPHEN-2-YL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-(PHENOXY)PROPANOIC ACID|LY 510929|GTPL2657|BDBM50145721	-	PUBCHEM	9890585	C26H25NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSPYUOBNIMILB-SANMLTNESA-N
29802	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9726	(2S)-3-[4-[2-(2-Cyclohexyl-5-methyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-methyl-2-phenoxypropanoic acid	(S)-3-{4-[2-(2-CYCLOHEXYL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-METHYL-2-PHENOXY-PROPIONIC ACID|BDBM50145719	-	PUBCHEM	11178750	C28H33NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OYRNUVYEOVJEPD-NDEPHWFRSA-N
29803	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9727	3-{4-[2-(2-Cyclohexyl-5-methyl-oxazol-4-yl)-ethoxy]-phenyl}-2-methyl-2-phenoxy-propionic acid	3-{4-[2-(2-CYCLOHEXYL-5-METHYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-METHYL-2-PHENOXY-PROPIONIC ACID|3-[4-[2-(2-CYCLOHEXYL-5-METHYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-METHYL-2-PHENOXYPROPANOIC ACID|BDBM50145718	-	PUBCHEM	11374677	C28H33NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OYRNUVYEOVJEPD-UHFFFAOYSA-N
29804	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9684	2-Methyl-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-phenoxy-propionic acid	2-METHYL-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PHENOXY-PROPIONIC ACID|2-METHYL-3-[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|BDBM50145712	-	PUBCHEM	10139247	C28H27NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSTSZHVRXHMZQK-UHFFFAOYSA-N
29805	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Xu Y (2004)	15115385	224915	9728	2-Methyl-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-phenoxypropanoic acid	2-METHYL-3-[4-[2-(5-METHYL-2-THIOPHEN-2-YL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]-2-PHENOXYPROPANOIC ACID|2-METHYL-3-{4-[2-(5-METHYL-2-THIOPHEN-2-YL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-2-PHENOXY-PROPIONIC ACID|BDBM50145710	-	PUBCHEM	10276539	C26H25NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSPYUOBNIMILB-UHFFFAOYSA-N
29806	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Baell JB (2004)	15084131	224916	9729	Methyl (1S,2R,3S,4R,5R,8R,11R,12R,15S,16S,22R,23R,24S)-3,4,23,24-tetraacetyloxy-22-(1-acetyloxyethyl)-11-hydroxy-2,5,15-trimethyl-9-methylidene-19-oxo-7,20-dioxahexacyclo[13.9.0.02,12.05,11.06,8.016,22]tetracos-17-ene-6-carboxylate	1-[12B-HYDROXY-1B,3A,10B-TRIMETHYL-2,3,4,5-TETRA(METHYLCARBONYLOXY)-14-METHYLENE-1A-METHYLOXYCARBONYL-8-OXO-1A,1B,2,3,3A,3B,4,5,5A,6,8,10A,10B,11,12,12A,12B,13,14,14A-ICOSAHYDROOXIRENO[2'',3'':7,8]CHRYSENO[2,1-C]OXEPIN-5-YL]ETHYL ACETATE|BDBM50145062	-	PUBCHEM	44315262	C40H52O16	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VKDXHXWBOARFPD-GMNMBZFNSA-N
29807	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wu TY (2004)	14698179	224917	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29808	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9730	5-[3-[3-(4-Cycloheptyloxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50133669	-	PUBCHEM	44345278	C28H35NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VSCDIBRPSQPEET-UHFFFAOYSA-N
29809	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9731	5-[3-[3-(4-Cyclopentyloxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50133667	-	PUBCHEM	44345252	C26H31NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BZLTUCWBZRKZHF-UHFFFAOYSA-N
29810	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9732	5-[3-[3-[2-Propyl-4-(cyclohexylmethyl)phenoxy]propoxy]phenyl]thiazolidine-2,4-dione	5-[3-[3-[2-PROPYL-4-(CYCLOHEXYLMETHYL)PHENOXY]PROPOXY]PHENYL]THIAZOLIDINE-2,4-DIONE|BDBM50133666	-	PUBCHEM	44345031	C28H35NO4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UJHOOSFHNXHHKX-UHFFFAOYSA-N
29811	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9733	(5S)-5-[3-[3-(4-Benzoyl-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50133663	-	PUBCHEM	70694429	C28H27NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OZZBRLWUSGYQBE-SANMLTNESA-N
29812	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9734	(5R)-5-[3-[3-[4-(1,2-Benzoxazol-3-yl)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50133661	-	PUBCHEM	54583265	C28H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLAXJZRUAXLLMT-AREMUKBSSA-N
29813	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9735	5-[3-[3-(4-Cyclohexyloxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50133658	-	PUBCHEM	44345458	C27H33NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GYMUSJRQCDBZCQ-UHFFFAOYSA-N
29814	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9736	5-[3-[3-[2-Propyl-4-(cyclohexylcarbonyl)phenoxy]propoxy]phenyl]thiazolidine-2,4-dione	5-[3-[3-[2-PROPYL-4-(CYCLOHEXYLCARBONYL)PHENOXY]PROPOXY]PHENYL]THIAZOLIDINE-2,4-DIONE|BDBM50133654	-	PUBCHEM	44344982	C28H33NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DSILKMLNLQMKEG-UHFFFAOYSA-N
29815	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	14505666	224918	9737	(5S)-5-[3-[3-(4-Phenoxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131503	-	PUBCHEM	54583268	C27H27NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZNLPWBJCSSSCCR-VWLOTQADSA-N
29816	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	unknown	target	Berger D (2003)	12941327	224919	9738	4-[3-Chloro-4-(1-methylimidazol-2-yl)sulfanylanilino]-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinoline-3-carbonitrile	3-CYANOQUINOLINE, 8|4-[3-CHLORO-4-(1-METHYL-1H-IMIDAZOLE-2-YLTHIO)PHENYLAMINO]-6-METHOXY-7-(3-MORPHOLINOPROPOXY)QUINOLINE-3-CARBONITRILE|4-[3-CHLORO-4-(1-METHYLIMIDAZOL-2-YL)SULFANYLANILINO]-6-METHOXY-7-(3-MORPHOLIN-4-YLPROPOXY)QUINOLINE-3-CARBONITRILE|4-({3-CHLORO-4-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]PHENYL}AMINO)-6-METHOXY-7-[3-(MORPHOLIN-4-YL)PROPOXY]QUINOLINE-3-CARBONITRILE|BDBM28123	-	PUBCHEM	10303277	C28H29ClN6O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QSENMPAGYMUVDE-UHFFFAOYSA-N
29817	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9739	(5R)-5-[3-[3-[4-(4-Hydroxyphenoxy)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131514	-	PUBCHEM	54587161	C27H27NO6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UMCOHKMLPVPQBF-RUZDIDTESA-N
29818	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9740	(5S)-5-[3-[3-[4-(4-Chloro-3-methylphenoxy)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131512	-	PUBCHEM	54580272	C28H28ClNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RHXBMPROSWDTQC-SANMLTNESA-N
29819	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9741	5-[3-[3-[2-Propyl-4-(3,4-dichlorophenoxy)phenoxy]propoxy]phenyl]thiazolidine-2,4-dione	5-[3-[3-[2-PROPYL-4-(3,4-DICHLOROPHENOXY)PHENOXY]PROPOXY]PHENYL]THIAZOLIDINE-2,4-DIONE|BDBM50131511	-	PUBCHEM	44327417	C27H25Cl2NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SXOUCNMFIUAZNE-UHFFFAOYSA-N
29820	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9742	(5S)-5-[3-[3-[4-(4-Fluorophenoxy)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131506	-	PUBCHEM	54584231	C27H26FNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BEESZPXMMFEPAP-VWLOTQADSA-N
29821	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9743	(5R)-5-[3-[3-[4-(4-Fluoro-3-methylphenoxy)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131505	-	PUBCHEM	54585196	C28H28FNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TVEAXARFLUXLEB-AREMUKBSSA-N
29822	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9744	(5R)-5-[3-[3-[4-(4-Chlorophenoxy)-2-propylphenoxy]propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131504	-	PUBCHEM	54585195	C27H26ClNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BSYLKYWBLKSLBJ-RUZDIDTESA-N
29823	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9737	(5S)-5-[3-[3-(4-Phenoxy-2-propylphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131503	-	PUBCHEM	54583268	C27H27NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZNLPWBJCSSSCCR-VWLOTQADSA-N
29824	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9745	(5S)-5-[3-[3-(4-Phenoxyphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131502	-	PUBCHEM	54581270	C24H21NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BTMVNTBNPIYHBM-QFIPXVFZSA-N
29825	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Ebdrup S (2003)	12672231	170525	6481	Ragaglitazar	NN-622|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID(-) DRF 2725|Q27088511|DRF-2725|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID|NNC-61-0029|(2S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YLETHOXY)PHENYL]PROPANOIC ACID|1NYX|DRF|(-)-DRF-2725|DRF2725|(S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID|DB07675|RAGAGLITAZAR|GTPL2664|BDBM50109551	-	DRUGBANK	DB07675	C25H25NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WMUIIGVAWPWQAW-DEOSSOPVSA-N
29826	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Santini C (2003)	12657263	224921	9746	2-[3-Chloro-4-[3-[4-[(Z)-C-ethyl-N-hydroxycarbonimidoyl]-3-hydroxy-2-propylphenoxy]propylsulfanyl]phenyl]acetic acid	3-CHLORO-4-[3-[2-PROPYL-3-HYDROXY-4-[1-(HYDROXYIMINO)PROPYL]PHENOXY]PROPYLTHIO]BENZENEACETIC ACID|BDBM50126019	-	PUBCHEM	136088972	C23H28ClNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLVVAYSKHQLKES-PLRJNAJWSA-N
29827	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Santini C (2003)	12657263	224921	9747	Benzeneacetic acid, 3-chloro-4-((3-((3-phenyl-7-propyl-6-benzofuranyl)oxy)propyl)thio)-	UNII-O937X0Z5EM|{3-CHLORO-4-[3-(3-PHENYL-7-PROPYL-BENZOFURAN-6-YLOXY)-PROPYLSULFANYL]-PHENYL}-ACETIC ACID|BENZENEACETIC ACID, 3-CHLORO-4-((3-((3-PHENYL-7-PROPYL-6-BENZOFURANYL)OXY)PROPYL)THIO)-|3-CHLORO-4-(3-(3-PHENYL-7-PROPYLBENZOFURAN-6-YLOXY)PROPYLTHIO)-PHENYLACETIC ACID|L-796,449|L796449|O937X0Z5EM|2-[3-CHLORO-4-[3-[(3-PHENYL-7-PROPYL-1-BENZOFURAN-6-YL)OXY]PROPYLSULFANYL]PHENYL]ACETIC ACID|L-796449|L 796449|Q27078434|{3-CHLORO-4-[3-(3-PHENYL-7-PROPYL-BENZOFURAN-6-YLOXY)-PROPYLSULFANYL]-PHENYL}-ACETIC ACID(L-796449)|GTPL2689|194608-80-5|BDBM50085040	-	PUBCHEM	9891946	C28H27ClO4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KAPDPGZDHUCILF-UHFFFAOYSA-N
29828	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Brooks DA (2001)	11405642	224922	9748	5-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione	AD 5061|AD-5061|BM-131246|AD 7057|AD5061|5-{4-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHOXY]BENZYL}-2,4-THIAZOLIDINEDIONE|GTPL2663|5-({4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}METHYL)-1,3-THIAZOLIDINE-2,4-DIONE|Q27074311|HY-101758|AD-7057|CS-6704|5-[[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]METHYL]-1,3-THIAZOLIDINE-2,4-DIONE|AD7057|BDBM50064451	-	PUBCHEM	9953271	C22H20N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GUTCYOKMCPFRGH-UHFFFAOYSA-N
29829	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Brooks DA (2001)	11405642	224922	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29830	109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	unknown	target	Coghlan MJ (2001)	11356099	224923	9575	N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-indan-5-yl]-3-methoxy-benzamide	N-((2R,3R)-3-(4-ETHYLPHENYLSULFONAMIDO)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-3-METHOXYBENZAMIDE|N-[3-(4-ETHYL-BENZENESULFONYLAMINO)-2-HYDROXY-INDAN-5-YL]-3-METHOXY-BENZAMIDE|BDBM50099581	-	PUBCHEM	17748224	C25H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KCRNOVULDSNKBZ-DNQXCXABSA-N
29831	109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	unknown	target	Coghlan MJ (2001)	11356099	224923	9749	Methyl (1S,2S,3S,4R,5S,6S,8R,12S,15S,16S,22R,23R,24S)-3,4,24-triacetyloxy-22-[(1R)-1-acetyloxyethyl]-2,5,15-trimethyl-9-methylidene-19-oxo-23-prop-1-en-2-yloxy-7,20-dioxahexacyclo[13.9.0.02,12.05,11.06,8.016,22]tetracos-17-ene-6-carboxylate	5-ISOPROPENYLOXY-1B,3A,10B-TRIMETHYL-2,3-DI(METHYLCARBONYLOXY)-5A-(1-METHYLCARBONYLOXYETHYL)-14-METHYLENE-1A-METHYLOXYCARBONYL-8-OXO-1A,1B,2,3,3A,3B,4,5,5A,6,8,10A,10B,11,12,12A,12B,13,14,14A-ICOSAHYDROOXIRENO[3'',2'':7,8]CHRYSENO[2,1-C]OXEPIN-4-YLACETA|BDBM50099583	-	PUBCHEM	44290049	C41H54O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VBCYJMDXVYKTHI-SMYFPHPLSA-N
29832	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Henke BR (1999)	10612594	224924	9750	2-Phenyl-3-(4-methoxyphenethyl)-1H-indole-5-acetic acid	{3-[2-(4-METHOXY-PHENYL)-ETHYL]-2-PHENYL-1H-INDOL-5-YL}-ACETIC ACID(GW 0207)|2-PHENYL-3-(4-METHOXYPHENETHYL)-1H-INDOLE-5-ACETIC ACID|258345-12-9|2-(3-(4-METHOXYPHENETHYL)-2-PHENYL-1H-INDOL-5-YL)ACETIC ACID|2-[3-[2-(4-METHOXYPHENYL)ETHYL]-2-PHENYL-1H-INDOL-5-YL]ACETIC ACID|{3-[2-(4-METHOXY-PHENYL)-ETHYL]-2-PHENYL-1H-INDOL-5-YL}-ACETIC ACID|GW0207|BDBM50083625	-	PUBCHEM	10068664	C25H23NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YZLHLVJLTOPOHC-UHFFFAOYSA-N
29833	111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	unknown	target	Parks DJ (1998)	9934490	224925	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion|Rosiglitazon|Rosiglitazonum|Rosiglitazone|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione|Rosiglitazona|BDBM50030474	phl-rosiglitazone|avandaryl|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03|A10BG02|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29834	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Cao K (2020)	32211658	226774	9929	Cisplatin	transplatin|cis-platin|cis-Diamminedichlorplatine|Dichloroplatinum diammoniate|cis-Diamineplatinum(II) dichloride|MFCD00011623|TP2450000|UNII:Q20Q21Q62J|TP2455000|Cisplatin impurity A	-	CHEMSPIDER	76401	H6Cl2N2Pt	small molecule	-	14913-33-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LXZZYRPGZAFOLE-UHFFFAOYSA-L
29835	107920	1540	HSPC057	CYLD	BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2	9606	Homo sapiens	inhibitor	target	Yamanaka S (2021)	33390248	226776	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MZBFFXLYQTWKNV-INIZCTEOSA-N
29836	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ishizawa J (2018)	29490944	228642	9913	DS-3032B	-	-	CHEMSPIDER	71060369	C37H44Cl2FN5O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WPJOGWGXMTUHPW-CIPNXXNHSA-N
29837	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Holzer P (2015)	26181851	224770	9193	Nvp-cgm097	ZINC253387855|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-[METHYL-[[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-7-PROPAN-2-YLOXY-1,4-DIHYDROISOQUINOLIN-3-ONE|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-[METHYL[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)-TRANS-CYCLOHEXYLMETHYL]AMINO]PHENYL)-1,4-DIHYDRO-2H-ISOQUINOLIN-3-ONE|4UF6MSL0ZH|NVP-CGM-097|KS-00000TSY|CCG-270337|US9051279, 106|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-(METHYL{[TRANS-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL}AMINO)PHENYL]-7-(PROPAN-2-YLOXY)-1,4-DIHYDROISOQUINOLIN-3(2H)-ONE|EX-A1059|CS-3138|HY-15954|NVP-CGM097 (CGM-097)|NVP-CGM097|Q27454942|NCGC00390552-01|W5747|4T4|NVP CGM097|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-{4-[METHYL({[(1R,4R)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL})AMINO]PHENYL}-7-(PROPAN-2-YLOXY)-1,2,3,4-TETRAHYDROISOQUINOLIN-3-ONE|C38H47CLN4O4|1313363-54-0|(1S)-1-(4-CHLOROPHENYL)-1,4-DIHYDRO-6-METHOXY-7-(1-METHYLETHOXY)-2-[4-[METHYL[[TRANS-4-(4-METHYL-3-OXO-1-PIPERAZINYL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-3(2H)-ISOQUINOLINONE|CGM-097|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-(METHYL(((1R,4S)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL)METHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE|UNII-4UF6MSL0ZH|A16326|AS-75288|S7875|CGM097|J3.509.326E|CGM 097|BCP18308|AKOS030526402|BDBM162123	-	PUBCHEM	53240420	C38H47ClN4O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CLRSLRWKONPSRQ-CPOWQTMSSA-N
29838	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Furet P (2016)	27542305	228643	9857	Siremadlin	-	-	CHEMSPIDER	27542305	C11H6F3N3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NJLJARSIRPKVMU-UHFFFAOYSA-N
29839	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Sun D (2014)	24456472	224788	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29840	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Yi H (2018)	29716622	228645	9893	APG-115	-	-	CHEMSPIDER	64853887	C34H38Cl2FN3O4	small molecule	-	1818393-16-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YJCZPJQGFSSFOL-MNZPCBJKSA-N
29841	113866	8237	RP4-659F15.2	USP11	UHX1	9606	Homo sapiens	inhibitor	target	Burkhart RA (2013)	23696131	156300	1192	Mitoxantrone	Mitoxantrona|Mitoxantronum|Mitoxantrone|1,4-DIHYDROXY-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-anthracenedione	mitoxantrone injection|mitoxan	DRUGBANK	DB01204	C22H28N4O6	small molecule	L01DB07	65271-80-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KKZJGLLVHKMTCM-UHFFFAOYSA-N
29842	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Tang WK (2019)	30591537	219833	9881	CB-5083	1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide|1H-Indole-4-carboxamide, 1-[7,8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-|CB-5083|591IV6UL6J	-	CHEMSPIDER	35519806	C24H23N5O2	small molecule	-	1542705-92-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RDALZZCKQFLGJP-UHFFFAOYSA-N
29843	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2013)	23316025	228646	9895	ML240	2-(2-Amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxy-4-quinazolinamine|ML240|CID-49830258|MFCD28137687|ML-240|2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine|4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-	-	CHEMSPIDER	34500429	C23H20N6O	small molecule	-	1346527-98-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NHAMBLRUUJAFOY-UHFFFAOYSA-N
29844	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2013)	23316025	228646	9927	ML241	N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine hydrochloride (1:1)|4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-, hydrochloride (1:1)	-	CHEMSPIDER	57251285	C23H25ClN4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DYHMHNNBOLCULH-UHFFFAOYSA-N
29845	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Poehler R (2018)	29271116	216019	9861	MSC1094308	4,4-Bis(4-fluorophenyl)-N-[(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methyl]-1-butanamine|1H-Carbazole-3-methanamine, N-[4,4-bis(4-fluorophenyl)butyl]-6-fluoro-2,3,4,9-tetrahydro-	-	CHEMSPIDER	78316408	C29H29F3N2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OCZIMUMAPGQEBH-UHFFFAOYSA-N
29846	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Magnaghi P (2013)	23892893	220331	9840	NMS-859	Acetamide, 2-chloro-N-[3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl]-|2-Chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]phenyl}acetamide	-	CHEMSPIDER	34224308	C15H12ClN3O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JWMFLBAPPIWNGG-UHFFFAOYSA-N
29847	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Sasazawa Y (2012)	22360440	228647	9900	Xanthohumol	2-propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-|Xanthohumol|(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one|MFCD00210576|2',4,4'-trihydroxy-6'-methoxy-3'-prenylchalcone|1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one|T4467YT1NT|(E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)propenone|(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one|XANTHOHUMOL FROM HOP (HUMULUS LUPULUS)|2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-	-	CHEMSPIDER	555077	C21H22O5	small molecule	-	569-83-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ORXQGKIUCDPEAJ-YRNVUSSQSA-N
29848	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Yoshimura C (2019)	31092565	228648	9877	TAS4464	7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-[(aminosulfonyl)amino]-5-deoxy-beta-D-ribofuranosyl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]-|7-[5-Deoxy-5-(sulfamoylamino)-beta-D-ribofuranosyl]-5-[(2-ethoxy-6-fluorophenyl)ethynyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	-	CHEMSPIDER	75533883	C21H23FN6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TZTRUHFXPVXWRD-QTQZEZTPSA-N
29849	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kuhn DJ (2007)	17591945	182023	7633	Carfilzomib	GTPL7420|SMR004660024|QCR-96|(2S)-4-METHYL-N-[(2S)-1-[[(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL]AMINO]-1-OXO-3-PHENYLPROPAN-2-YL]-2-[[(2S)-2-[(2-MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL]AMINO]PENTANAMIDE|DSSTOX_RID_82886|CARFILZOMIB (JAN/USAN/INN)|(2S)-N-((1S)-1-BENZYL-2-(((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRAN-2-YL)CARBONYL)BUTYL)AMINO)-2-OXOETHYL)-4-METHYL-2-(((2S)-2-((MORPHOLIN-4-YLACETYL)AMINO)-4-PHENYLBUTANOYL)AMINO)PENTANAMIDE|CS-0984|72X6E3J5AR|HY-10455|UNII-72X6E3J5AR|CC-684|EX-A2037|ZINC49841054|CARFILZOMIB; PR171|N-{(2S)-2-[(MORPHOLIN-4-YLACETYL)AMINO]-4-PHENYLBUTANOYL}-L-LEUCYL-N-{(2S)-4-METHYL-1-[(2R)-2-METHYLOXIRAN-2-YL]-1-OXOPENTAN-2-YL}-L-PHENYLALANINAMIDE|KYPROLIS|NCGC00249613-02|AKOS025401910|SC-91032|D08880|AOB87759|Y0441|AB01565867_02|(ALPHAS)-ALPHA-[[2-(4-MORPHOLINYL)ACETYL]AMINO]BENZENEBUTANOYL-L-LEUCYL-N-[(1S)-3-METHYL-1-[[(2R)-2-METHYL-2-OXIRANYL]CARBONYL]BUTYL]-L-PHENYLALANINAMIDE|SR-01000941582|CARFILZOMIB [USAN:INN]|ONO-7057|L-PHENYLALANINAMIDE, (ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-|CARFILZOMIB|CARFILZOMIB?PR-171?/KYPROLIS|AS-17059|PR-171|C40H57N5O7|SR-01000941582-1|Q15366934|(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|(S)-4-METHYL-N-((S)-1-((S)-4-METHYL-1-((R)-2- METHYLOXIRAN-2-YL)-1 -OXOPENTAN-2-YLAMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE|CARFILZOMIB (PR-171)|TOX21_113079_1|AB0008111|DSSTOX_CID_28616|KS-00000SR1|MLS006011102|NCGC00249613-03|AK546882|CCG-270405|TOX21_113079|NCGC00249613-11|S2853|868540-17-4|AC-27051|NCGC00249613-01|(ALPHAS)-ALPHA-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-L-PHE NYLALANINAMIDE|J-501773|SW218090-2|SB16813|KYPROLIS (TN)|CARFILZOMIB(PR171)|CS-W004540|DB08889|DSSTOX_GSID_48690|S-7798|DTXSID4048690|BDBM50277889	kyprolis	DRUGBANK	DB08889	C40H57N5O7	small molecule	L01XX45	868540-17-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BLMPQMFVWMYDKT-NZTKNTHTSA-N
29850	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Kraus M (2015)	26069288	228649	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
29851	111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	inhibitor	target	Kraus M (2015)	26069288	228649	181	Bortezomib	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE|N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide|[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid|BDBM50069989	act bortezomib|velcade|bortezo	DRUGBANK	DB00188	C19H25BN4O4	small molecule	L01XX32	179324-69-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXJABQQUPOEUTA-RDJZCZTQSA-N
29852	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Kraus M (2015)	26069288	228649	9934	LU-102	N-[1-[4-(Aminomethyl)-3-methylsulfonylphenyl]but-3-en-2-yl]-5-[[(2S)-2-azido-3-phenylpropanoyl]amino]-2-(2-methylpropyl)-4-oxooctanamide|N3Phe-Leu-Leu-Phe(4-CH2NH2)VS|azido-phenylalanyl-leucyl-leucyl-4-aminomethylphenylalanyl methyl vinyl sulfone|azido-Phe-Leu-Leu-4-aminomethyl-Phe-methyl vinyl sulfone	-	PUBCHEM	122381404	C33H46N6O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KSYVIWDORIKTLM-VMYWCARFSA-N
29853	111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	inhibitor	target	Kraus M (2015)	26069288	228649	9934	LU-102	N-[1-[4-(Aminomethyl)-3-methylsulfonylphenyl]but-3-en-2-yl]-5-[[(2S)-2-azido-3-phenylpropanoyl]amino]-2-(2-methylpropyl)-4-oxooctanamide|N3Phe-Leu-Leu-Phe(4-CH2NH2)VS|azido-phenylalanyl-leucyl-leucyl-4-aminomethylphenylalanyl methyl vinyl sulfone|azido-Phe-Leu-Leu-4-aminomethyl-Phe-methyl vinyl sulfone	-	PUBCHEM	122381404	C33H46N6O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KSYVIWDORIKTLM-VMYWCARFSA-N
29854	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	List A (2014)	24285701	228650	9842	Omuralide	6-Oxa-2-azabicyclo[3.2.0]heptane-3,7-dione, 1-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-, (1S,4R,5S)-|(1S,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione	-	CHEMSPIDER	24704745	C10H15NO4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FWPWHHUJACGNMZ-NUMRIWBASA-N
29855	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Yang H (2008)	18537678	228651	9908	Lactacystin	Lactacystin|N-Acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinyl}carbonyl)-L-cysteine|L-cysteine, S-[[(2R,3S,4R)-3,4-dihydro-3,5-dihydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-2H-pyrrol-2-yl]carbonyl]-N-(1-hydroxyethylidene)-, (E)-|N-Acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)-L-cysteine|L-Cysteine, N-acetyl-S-[[(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinyl]carbonyl]-|MFCD01076525	-	CHEMSPIDER	5042546	C15H24N2O7S	small molecule	-	133343-34-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DAQAKHDKYAWHCG-RWTHQLGUSA-N
29856	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Yang H (2008)	18537678	228651	9892	Epigallocatechin gallate	EGCG|Epigallocatechin 3-gallate|Epigallocatechin gallate|(-)-Epigallocatechin gallate|(-)-EGCG|(-)-Epigallocatechin-3-o-gallate|(-)-epigallocatechin 3-gallate|(2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate|Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester|(-)-Epigallocatechin 3-O-gallate|3,4,5-Trihydroxybenzoic acid (2R-cis)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester|(-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate|KB5200000|MFCD00075940|(-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate	-	CHEMSPIDER	58575	C22H18O11	small molecule	-	989-51-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WMBWREPUVVBILR-WIYYLYMNSA-N
29857	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Chen D (2005)	15857606	228652	6168	apigenin	-	-	DRUGBANK	DB07352	C15H10O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KZNIFHPLKGYRTM-UHFFFAOYSA-N
29858	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Chen D (2005)	15857606	228652	4044	Quercetin	3,5,7,3',4'-Pentahydroxyflavone	-	DRUGBANK	DB04216	C15H10O7	small molecule	-	117-39-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	REFJWTPEDVJJIY-UHFFFAOYSA-N
29859	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kazi A (2003)	12963483	142316	1582	Genistein	Genisterin|5,7,4'-Trihydroxyisoflavone|4',5, 7-Trihydroxyisoflavone|Genisteol	-	DRUGBANK	DB01645	C15H10O5	small molecule	-	446-72-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TZBJGXHYKVUXJN-UHFFFAOYSA-N
29860	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Yang H (2006)	16651429	228653	9878	Celastrol	Celastrol|Tripterine|(2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid|2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, (2R,4aS,6aS,12bR,14aS,14bR)-|(2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylic acid|Tripterin|MFCD03424073|10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid|L8GG98663L	-	CHEMSPIDER	109405	C29H38O4	small molecule	-	34157-83-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KQJSQWZMSAGSHN-JJWQIEBTSA-N
29861	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Yang H (2008)	17541980	228654	9851	Pristimerin	Pristimerin|Celastrol-methylether|Methyl (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylate|2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-, methyl ester, (2R,4aS,6aS,12bR,14aS,14bR)-|Methyl (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylate|MFCD01711331|CELASTROL METHYL ESTER|(9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26 -trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester|28ZK7PR57S	-	CHEMSPIDER	140269	C30H40O4	small molecule	-	1258-84-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JFACETXYABVHFD-WXPPGMDDSA-N
29862	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kisselev AF (2012)	22284358	228655	9836	MLN9708	MLN9708|IXAZOMIB CITRATE 1,3,2-DIOXABORINANE|4-(Carboxymethyl)-2-[(1R)-1-{[N-(2,5-dichlorobenzoyl)glycyl]amino}-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid|1,3,2-Dioxaborinane-4-acetic acid, 4-carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-|Ninlaro|ixazomib|MLN-9708	-	CHEMSPIDER	25027413	C20H23BCl2N2O9	small molecule	-	1201902-80-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YTXSYWAKVMZICI-PVCZSOGJSA-N
29863	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hines J (2008)	18482702	228656	9837	Fellutamide B	N~2~-[(3R)-3-Hydroxydodecanoyl]-L-asparaginyl-N~1~-(4-methyl-1-oxo-2-pentanyl)-L-glutamamide|L-Glutamamide, N~2~-[(3R)-3-hydroxy-1-oxododecyl]-L-asparaginyl-N~1~-(1-formyl-3-methylbutyl)-	-	CHEMSPIDER	17209898	C27H49N5O7	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MFXAGCQVWGPEJH-FTMYTLCRSA-N
29864	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Rydzewski RM (2006)	16686537	132619	9917	PSI	PSI|tert-Butyl (4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxopentan-2-yl]amino}-1-oxopropan-2-yl]amino}-5-oxopentanoate (non-preferred name)|MFCD00671409|Z-Ile-Glu(O-t-butyl)-Ala-Leucinal	-	CHEMSPIDER	8136267	C32H50N4O8	small molecule	-	158442-41-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TYFTWYMXUWCOOB-YICLCXKGSA-N
29865	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Meng L (1999)	10468620	133715	9924	Epoxomicin	Epoxomicin|L-Threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-|N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide|MFCD03791061|Y0900I3U8U|N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-threoninamide	-	CHEMSPIDER	9401737	C28H50N4O7	small molecule	-	134381-21-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOGIDQKFVLKMLQ-JTHVHQAWSA-N
29866	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Meng L (1999)	10383134	228657	9845	Eponemycin	N-[(2S)-3-Hydroxy-1-({(2S)-1-[(2R)-2-(hydroxymethyl)-2-oxiranyl]-4-methyl-1-oxo-4-penten-2-yl}amino)-1-oxo-2-propanyl]-6-methylheptanamide|Heptanamide, N-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)oxiranyl]carbonyl]-3-methyl-3-buten-1-yl]amino]-2-oxoethyl]-6-methyl-	-	CHEMSPIDER	8267816	C20H34N2O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZPLVYYNMRMBNGE-TWOQFEAHSA-N
29867	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Meng L (1999)	10383134	228657	9845	Eponemycin	N-[(2S)-3-Hydroxy-1-({(2S)-1-[(2R)-2-(hydroxymethyl)-2-oxiranyl]-4-methyl-1-oxo-4-penten-2-yl}amino)-1-oxo-2-propanyl]-6-methylheptanamide|Heptanamide, N-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)oxiranyl]carbonyl]-3-methyl-3-buten-1-yl]amino]-2-oxoethyl]-6-methyl-	-	CHEMSPIDER	8267816	C20H34N2O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZPLVYYNMRMBNGE-TWOQFEAHSA-N
29868	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kisselev AF (2012)	22284358	228655	9911	PS-519	PS-519	-	CHEMSPIDER	8052873	C12H19NO4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KMXHEXRPYSXLRN-JDVQERKKSA-N
29869	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kawamura S (2013)	23547757	228658	9889	Belactosin A	L-Alanyl-3-{(1S,2S)-2-[({(2R,3S)-3-[(2S)-2-butanyl]-4-oxo-2-oxetanyl}carbonyl)amino]cyclopropyl}-L-alanine|L-Alanine, L-alanyl-3-[(1S,2S)-2-[[[(2R,3S)-3-[(1S)-1-methylpropyl]-4-oxo-2-oxetanyl]carbonyl]amino]cyclopropyl]-	-	CHEMSPIDER	24704887	C17H27N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZSYIAUXMQLVKIL-BLTCOFLISA-N
29870	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Kawamura S (2013)	23547757	228658	9889	Belactosin A	L-Alanyl-3-{(1S,2S)-2-[({(2R,3S)-3-[(2S)-2-butanyl]-4-oxo-2-oxetanyl}carbonyl)amino]cyclopropyl}-L-alanine|L-Alanine, L-alanyl-3-[(1S,2S)-2-[[[(2R,3S)-3-[(1S)-1-methylpropyl]-4-oxo-2-oxetanyl]carbonyl]amino]cyclopropyl]-	-	CHEMSPIDER	24704887	C17H27N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZSYIAUXMQLVKIL-BLTCOFLISA-N
29871	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9931	Tyropeptin A	N-(3-methylbutanoyl)-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxopropan-2-yl]-L-valinamide|L-Valinamide, N-(3-methyl-1-oxobutyl)-L-tyrosyl-N-[1-formyl-2-(4-hydroxyphenyl)ethyl]-|Tyropeptin A|N-(3-Methylbutanoyl)-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxo-2-propanyl]-L-valinamide	-	CHEMSPIDER	9908676	C28H37N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OSMJFYFZOAVCNP-KLZDYHPHSA-N
29872	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9931	Tyropeptin A	N-(3-methylbutanoyl)-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxopropan-2-yl]-L-valinamide|L-Valinamide, N-(3-methyl-1-oxobutyl)-L-tyrosyl-N-[1-formyl-2-(4-hydroxyphenyl)ethyl]-|Tyropeptin A|N-(3-Methylbutanoyl)-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxo-2-propanyl]-L-valinamide	-	CHEMSPIDER	9908676	C28H37N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OSMJFYFZOAVCNP-KLZDYHPHSA-N
29873	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9925	Tyropeptin B	N-Butyryl-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxo-2-propanyl]-L-leucinamide|L-Leucinamide, N-(1-oxobutyl)-L-tyrosyl-N-[1-formyl-2-(4-hydroxyphenyl)ethyl]-	-	CHEMSPIDER	9202817	C28H37N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SYAOZPXWOOYNES-MHKYCTGGSA-N
29874	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9925	Tyropeptin B	N-Butyryl-L-tyrosyl-N-[1-(4-hydroxyphenyl)-3-oxo-2-propanyl]-L-leucinamide|L-Leucinamide, N-(1-oxobutyl)-L-tyrosyl-N-[1-formyl-2-(4-hydroxyphenyl)ethyl]-	-	CHEMSPIDER	9202817	C28H37N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SYAOZPXWOOYNES-MHKYCTGGSA-N
29875	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Momose I (2007)	17420589	228660	9896	TP-110	O-methyl-N-(naphthalen-1-ylacetyl)-L-tyrosyl-N-[1-(4-methoxyphenyl)-3-oxopropan-2-yl]-L-valinamide|L-Valinamide, O-methyl-N-[2-(1-naphthalenyl)acetyl]-L-tyrosyl-N-[1-formyl-2-(4-methoxyphenyl)ethyl]-|O-Methyl-N-(1-naphthylacetyl)-L-tyrosyl-N-[1-(4-methoxyphenyl)-3-oxo-2-propanyl]-L-valinamide	-	CHEMSPIDER	9767341	C37H41N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IJDYUMDIJFFMQQ-ROSKKCPQSA-N
29876	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kroll M (1999)	10508680	228661	9843	Gliotoxin	Gliotoxin|[3R-(3a,5ab,6b,10aa)]-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione|(1R,7S,8S,11R)-7-Hydroxy-11-(hydroxymethyl)-15-methyl-12,13-dithia-9,15-diazatetracyclo[9.2.2.0~1,9~.0~3,8~]pentadeca-3,5-diene-10,14-dione|10H-3,10a-(Iminomethano)[1,2,4]dithiazino[4,3-a]indole-4,11(3H)-dione, 5a,6-dihydro-6-hydroxy-3-(hydroxymethyl)-12-methyl-, (3R,5aS,6S,10aR)-|(3R,5aS,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione|(3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione|epithiodiketopiperazine|KB4725000|MFCD00058534|50675|5L648PH06K|Aspergillin solution|Gliotoxin solution	-	CHEMSPIDER	5988	C13H14N2O4S2	small molecule	-	67-99-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FIVPIPIDMRVLAY-RBJBARPLSA-N
29877	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Ozcan S (2013)	23547706	228662	9914	PI-1840	N-Isopropyl-2-(4-propylphenoxy)-N-{[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl}acetamide|Acetamide, N-(1-methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-	-	CHEMSPIDER	29403217	C22H26N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZVVXAODXPVWGMF-UHFFFAOYSA-N
29878	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Groll M (2001)	11493007	55322	9909	TMC-95A	TMC-95A	-	CHEMSPIDER	8050373	C33H38N6O10	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZIAXNZCTODBCKW-BOYGTWLISA-N
29879	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Groll M (2001)	11493007	55322	9909	TMC-95A	TMC-95A	-	CHEMSPIDER	8050373	C33H38N6O10	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZIAXNZCTODBCKW-BOYGTWLISA-N
29880	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Groll M (2001)	11493007	55322	9909	TMC-95A	TMC-95A	-	CHEMSPIDER	8050373	C33H38N6O10	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZIAXNZCTODBCKW-BOYGTWLISA-N
29881	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	inhibitor	target	Yang Y (2019)	31038581	219731	9863	SKPin C1	SKPin C1|Acetic acid, 2-[4-bromo-2-[(E)-[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]-|(4-Bromo-2-{(E)-[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)acetic acid	-	CHEMSPIDER	35308320	C18H13BrN2O4S2	small molecule	-	432001-69-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IYCJJVVXEHZJHE-VIZOYTHASA-N
29882	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Cai Q (2011)	21443232	228663	9886	AT-406	Pyrrolo[1,2-a][1,5]diazocine-8-carboxamide, N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-, (5S,8S,10aR)-|AT-406|N65WC8PXDD|(5S,8S,10aR)-N-(Diphenylmethyl)-5-[(N-methyl-L-alanyl)amino]-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide	-	CHEMSPIDER	28424114	C32H43N5O4	small molecule	-	1071992-81-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSXUTRRVVSPWDZ-MKKUMYSQSA-N
29883	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	inhibitor	target	Cai Q (2011)	21443232	228663	9886	AT-406	Pyrrolo[1,2-a][1,5]diazocine-8-carboxamide, N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-, (5S,8S,10aR)-|AT-406|N65WC8PXDD|(5S,8S,10aR)-N-(Diphenylmethyl)-5-[(N-methyl-L-alanyl)amino]-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide	-	CHEMSPIDER	28424114	C32H43N5O4	small molecule	-	1071992-81-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSXUTRRVVSPWDZ-MKKUMYSQSA-N
29884	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Cai Q (2011)	21443232	228663	9886	AT-406	Pyrrolo[1,2-a][1,5]diazocine-8-carboxamide, N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-, (5S,8S,10aR)-|AT-406|N65WC8PXDD|(5S,8S,10aR)-N-(Diphenylmethyl)-5-[(N-methyl-L-alanyl)amino]-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide	-	CHEMSPIDER	28424114	C32H43N5O4	small molecule	-	1071992-81-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSXUTRRVVSPWDZ-MKKUMYSQSA-N
29885	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Ardecky RJ (2013)	23743278	228664	9868	GDC-0152	2-Pyrrolidinecarboxamide, 1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-, (2S)-|GDC-0152|L-alpha-Glutamyl-L-tryptophyl-L-glutamic acid|4KW1M48SHS|1-{(2S)-2-Cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide	-	CHEMSPIDER	28521870	C25H34N6O3S	small molecule	-	873652-48-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WZRFLSDVFPIXOV-LRQRDZAKSA-N
29886	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Archer CR (2012)	22870914	228665	9855	Syringolin A	L-Valine, N-[[[(1S)-2-methyl-1-[[[(3E,5S,8S,9E)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino]carbonyl]propyl]amino]carbonyl]-|N-{[(2S)-1-{[(3E,5S,8S,9E)-5-Isopropyl-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino}-3-methyl-1-oxo-2-butanyl]carbamoyl}-L-valine|syringolin A	-	CHEMSPIDER	25058932	C24H39N5O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RUWSLQOIGKYPEZ-YPXRAQKDSA-N
29887	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Archer CR (2012)	22870914	228665	9855	Syringolin A	L-Valine, N-[[[(1S)-2-methyl-1-[[[(3E,5S,8S,9E)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino]carbonyl]propyl]amino]carbonyl]-|N-{[(2S)-1-{[(3E,5S,8S,9E)-5-Isopropyl-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino}-3-methyl-1-oxo-2-butanyl]carbamoyl}-L-valine|syringolin A	-	CHEMSPIDER	25058932	C24H39N5O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RUWSLQOIGKYPEZ-YPXRAQKDSA-N
29888	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Archer CR (2012)	22870914	228665	9855	Syringolin A	L-Valine, N-[[[(1S)-2-methyl-1-[[[(3E,5S,8S,9E)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino]carbonyl]propyl]amino]carbonyl]-|N-{[(2S)-1-{[(3E,5S,8S,9E)-5-Isopropyl-2,7-dioxo-1,6-diazacyclododeca-3,9-dien-8-yl]amino}-3-methyl-1-oxo-2-butanyl]carbamoyl}-L-valine|syringolin A	-	CHEMSPIDER	25058932	C24H39N5O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RUWSLQOIGKYPEZ-YPXRAQKDSA-N
29889	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9899	Glidobactin A	2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-|(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide	-	CHEMSPIDER	4943654	C27H44N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TYGJUQYJMIOZLZ-QQXADAIISA-N
29890	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9899	Glidobactin A	2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-|(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide	-	CHEMSPIDER	4943654	C27H44N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TYGJUQYJMIOZLZ-QQXADAIISA-N
29891	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9899	Glidobactin A	2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-|(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide	-	CHEMSPIDER	4943654	C27H44N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TYGJUQYJMIOZLZ-QQXADAIISA-N
29892	111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9899	Glidobactin A	2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-|(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide	-	CHEMSPIDER	4943654	C27H44N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TYGJUQYJMIOZLZ-QQXADAIISA-N
29893	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9847	Glidobactin C	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-tetradecadienamide|2,4-Tetradecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	4943596	C29H48N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UHXDSKADPILIPT-OHIHYABUSA-N
29894	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9847	Glidobactin C	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-tetradecadienamide|2,4-Tetradecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	4943596	C29H48N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UHXDSKADPILIPT-OHIHYABUSA-N
29895	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9847	Glidobactin C	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-tetradecadienamide|2,4-Tetradecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	4943596	C29H48N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UHXDSKADPILIPT-OHIHYABUSA-N
29896	111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	inhibitor	target	Pawar A (2020)	32123742	228666	9847	Glidobactin C	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-tetradecadienamide|2,4-Tetradecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	4943596	C29H48N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UHXDSKADPILIPT-OHIHYABUSA-N
29897	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Clerc J (2009)	19359491	228667	9871	Syringolin B	L-Valine, N-[[[(1S)-2-methyl-1-[[[(3E,5S,8S)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]amino]carbonyl]-|N-{[(2S)-1-{[(3E,5S,8S)-5-Isopropyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-3-methyl-1-oxo-2-butanyl]carbamoyl}-L-valine|syringolin B	-	CHEMSPIDER	26329033	C24H41N5O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AIMDTYKFJMYVNG-NGGLIGEOSA-N
29898	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9885	Cepafungin I	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-11-methyl-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-11-methyl-, (2E,4E)-	-	CHEMSPIDER	4943721	C28H46N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SVHNVAFCZJDSIW-VBFMYEFXSA-N
29899	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9885	Cepafungin I	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-11-methyl-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-11-methyl-, (2E,4E)-	-	CHEMSPIDER	4943721	C28H46N4O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SVHNVAFCZJDSIW-VBFMYEFXSA-N
29900	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9894	Luminmycin A	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	28646456	C27H44N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CXVPCSSIDACGGV-SBSLBVBZSA-N
29901	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9894	Luminmycin A	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	28646456	C27H44N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CXVPCSSIDACGGV-SBSLBVBZSA-N
29902	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9894	Luminmycin A	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	28646456	C27H44N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CXVPCSSIDACGGV-SBSLBVBZSA-N
29903	111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9894	Luminmycin A	(2E,4E)-N-[(2S,3R)-3-Hydroxy-1-{[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino}-1-oxo-2-butanyl]-2,4-dodecadienamide|2,4-Dodecadienamide, N-[(1S,2R)-2-hydroxy-1-[[[(3E,5S,8S)-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]carbonyl]propyl]-, (2E,4E)-	-	CHEMSPIDER	28646456	C27H44N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CXVPCSSIDACGGV-SBSLBVBZSA-N
29904	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9912	TMC-95B	TMC-95B	-	CHEMSPIDER	8253792	C33H38N6O10	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZIAXNZCTODBCKW-NKGUOCGVSA-N
29905	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9912	TMC-95B	TMC-95B	-	CHEMSPIDER	8253792	C33H38N6O10	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZIAXNZCTODBCKW-NKGUOCGVSA-N
29906	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Nickeleit I (2008)	18598941	228668	9884	Argyrin A	Argyrin	-	CHEMSPIDER	9279960	C40H44N10O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MXGWDBFUMHUPTG-SKZNYKRCSA-N
29907	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Nickeleit I (2008)	18598941	228668	9884	Argyrin A	Argyrin	-	CHEMSPIDER	9279960	C40H44N10O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MXGWDBFUMHUPTG-SKZNYKRCSA-N
29908	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Nickeleit I (2008)	18598941	228668	9884	Argyrin A	Argyrin	-	CHEMSPIDER	9279960	C40H44N10O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MXGWDBFUMHUPTG-SKZNYKRCSA-N
29909	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Allardyce DJ (2019)	31074944	228669	9928	Argyrin B	argyrin B	-	CHEMSPIDER	8116406	C41H46N10O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OVJDNZFLEREPKG-VPMCBBNJSA-N
29910	111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	inhibitor	target	Allardyce DJ (2019)	31074944	228669	9928	Argyrin B	argyrin B	-	CHEMSPIDER	8116406	C41H46N10O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OVJDNZFLEREPKG-VPMCBBNJSA-N
29911	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Buelow L (2010)	20358576	228670	9848	Argyrin F	-	-	CHEMSPIDER	9258555	C40H44N10O9S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FJSMXOTZGJRIEU-GZAHMLPMSA-N
29912	111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	inhibitor	target	Buelow L (2010)	20358576	228670	9848	Argyrin F	-	-	CHEMSPIDER	9258555	C40H44N10O9S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FJSMXOTZGJRIEU-GZAHMLPMSA-N
29913	111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	inhibitor	target	Buelow L (2010)	20358576	228670	9848	Argyrin F	-	-	CHEMSPIDER	9258555	C40H44N10O9S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FJSMXOTZGJRIEU-GZAHMLPMSA-N
29914	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9888	Phepropeptin A	Cyclo(D-leucyl-L-valyl-L-leucyl-D-phenylalanyl-L-prolyl-L-leucyl)	-	CHEMSPIDER	9214884	C37H58N6O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QVOWLQGIVUTHGK-ZAFXZDQFSA-N
29915	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9867	Phepropeptin B	Cyclo(D-leucyl-L-valyl-L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl)	-	CHEMSPIDER	9040729	C40H56N6O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WPYOCTODIOSRQG-WOXDTIJASA-N
29916	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9875	Phepropeptin C	Cyclo(L-alloisoleucyl-L-leucyl-D-phenylalanyl-D-prolyl-L-leucyl-D-leucyl)	-	CHEMSPIDER	78437893	C38H60N6O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AKQUYKYHJPCGHJ-OMPYVEQSSA-N
29917	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9915	Phepropeptin D	Cyclo(L-alloisoleucyl-L-leucyl-D-phenylalanyl-D-prolyl-L-phenylalanyl-D-leucyl)	-	CHEMSPIDER	78438532	C41H58N6O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RDFYNJULNCUNKD-SJZSTPBESA-N
29918	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Hubbell GE (2020)	33791679	228659	9852	Scytonemide A	3-[(2R,5S,8S,11S,14S,15Z,17S)-5-[(2S)-2-Butanyl]-17-(4-hydroxybenzyl)-8-(hydroxymethyl)-14-isobutyl-11-isopropyl-3,6,9,12,18,21-hexaoxo-1,4,7,10,13,16,19-heptaazacyclohenicos-15-en-2-yl]propanamide|Scytonemide A	-	CHEMSPIDER	35518448	C36H56N8O9	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HJKXQQVDTIEFDD-FAVUQDIBSA-N
29919	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Ward GA (2018)	29695633	228671	9891	ASTX660	1-[6-(4-Fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-{[(3R)-3-methyl-4-morpholinyl]methyl}-1-piperazinyl]ethanone|Ethanone, 1-[6-[(4-fluorophenyl)methyl]-2,3-dihydro-5-(hydroxymethyl)-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methyl-4-morpholinyl]methyl]-1-piperazinyl]-	-	CHEMSPIDER	71061559	C30H42FN5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YCXOHEXZVKOGEV-DNRQZRRGSA-N
29920	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Ward GA (2018)	29695633	228671	9891	ASTX660	1-[6-(4-Fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-{[(3R)-3-methyl-4-morpholinyl]methyl}-1-piperazinyl]ethanone|Ethanone, 1-[6-[(4-fluorophenyl)methyl]-2,3-dihydro-5-(hydroxymethyl)-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methyl-4-morpholinyl]methyl]-1-piperazinyl]-	-	CHEMSPIDER	71061559	C30H42FN5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YCXOHEXZVKOGEV-DNRQZRRGSA-N
29921	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Hennessy EJ (2013)	24320998	228672	9883	AZD5582	AZD5582|AZD 5582|2-Pyrrolidinecarboxamide, N,N'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-, (2S,2'S)-	-	CHEMSPIDER	31133160	C58H78N8O8	small molecule	-	1258392-53-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WLMCRYCCYXHPQF-ZVMUOSSASA-N
29922	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	inhibitor	target	Hennessy EJ (2013)	24320998	228672	9883	AZD5582	AZD5582|AZD 5582|2-Pyrrolidinecarboxamide, N,N'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-, (2S,2'S)-	-	CHEMSPIDER	31133160	C58H78N8O8	small molecule	-	1258392-53-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WLMCRYCCYXHPQF-ZVMUOSSASA-N
29923	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Hennessy EJ (2013)	24320998	228672	9883	AZD5582	AZD5582|AZD 5582|2-Pyrrolidinecarboxamide, N,N'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-, (2S,2'S)-	-	CHEMSPIDER	31133160	C58H78N8O8	small molecule	-	1258392-53-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WLMCRYCCYXHPQF-ZVMUOSSASA-N
29924	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Sun H (2007)	17999504	228673	9923	SM-164	SM-164	-	CHEMSPIDER	26335076	C62H84N14O6	small molecule	-	957135-43-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LGYDZXNSSLRFJS-IOQQVAQYSA-N
29925	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Nikolovska-Coleska Z (2004)	15115387	212873	9930	Embelin	Embelin|2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione|2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl-|2,5-Dihydroxy-3-undecyl-1,4-benzoquinone|Embelic acid|Emberine|MFCD00016369	-	CHEMSPIDER	3105	C17H26O4	small molecule	-	550-24-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IRSFLDGTOHBADP-UHFFFAOYSA-N
29926	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Kester RF (2013)	24093940	165954	9862	LCL-161	N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N~2~-methylalaninamide|Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-|LCL-161|6TNS415Y3P	-	CHEMSPIDER	30687709	C26H33FN4O3S	small molecule	-	1005342-46-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UFPFGVNKHCLJJO-SSKFGXFMSA-N
29927	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Kester RF (2013)	24093940	165954	9862	LCL-161	N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N~2~-methylalaninamide|Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-|LCL-161|6TNS415Y3P	-	CHEMSPIDER	30687709	C26H33FN4O3S	small molecule	-	1005342-46-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UFPFGVNKHCLJJO-SSKFGXFMSA-N
29928	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Yang H (2009)	19165859	138350	9866	Shikonin	Shikonin|1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-|1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-|5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-naphthoquinone|5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthoquinone|3IK6592UBW|(+)-Alkannin	-	CHEMSPIDER	420739	C16H16O5	small molecule	-	517-89-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NEZONWMXZKDMKF-SNVBAGLBSA-N
29929	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kazi A (2014)	24570003	220336	9914	PI-1840	N-Isopropyl-2-(4-propylphenoxy)-N-{[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl}acetamide|Acetamide, N-(1-methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-	-	CHEMSPIDER	29403217	C22H26N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZVVXAODXPVWGMF-UHFFFAOYSA-N
29930	115863	10617	-	STAMBP	AMSH|MICCAP	9606	Homo sapiens	inhibitor	target	Bednash JS (2017)	28492230	211768	9876	BC-1471	N-(2-Furylmethyl)-2-{[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-3,4-dihydro-2-quinazolinyl]sulfanyl}acetamide|Acetamide, 2-[[3,4-dihydro-6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-(2-furanylmethyl)-	-	CHEMSPIDER	2541949	C27H28N4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HBAWGWWMULJGHR-UHFFFAOYSA-N
29931	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Ndubaku C (2015)	25364867	228674	9922	2-phenylbenzo[f][1,3]benzoxazole-4,9-dione	-	-	CHEMSPIDER	444479	C17H9NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CMYQQADDUUDCCA-UHFFFAOYSA-N
29932	116077	10868	-	USP20	LSFR3A|VDU2|hVDU2	9606	Homo sapiens	inhibitor	target	Harrigan JA (2018)	28959952	228675	9864	2-Amino-6-[(E)-2-(3-fluorophenyl)vinyl]-1H-indole-3-carbonitrile	1H-Indole-3-carbonitrile, 2-amino-6-[(E)-2-(3-fluorophenyl)ethenyl]-|2-Amino-6-[(E)-2-(3-fluorophenyl)vinyl]-1H-indole-3-carbonitrile	-	CHEMSPIDER	71117287	C17H12FN3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CGXBPMZRTMXEIA-SNAWJCMRSA-N
29933	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Potu H (2014)	24980819	228676	9910	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide|2-Propenamide, 2-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-, (2E)-	-	CHEMSPIDER	86595640	C25H28Cl2N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IIKVQQNZHGBYGQ-KNTRCKAVSA-N
29934	113867	8239	RP5-1172N10.4	USP9X	DFFRX|FAF|FAM|MRX99	9606	Homo sapiens	inhibitor	target	Potu H (2014)	24980819	228676	9910	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide|2-Propenamide, 2-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-, (2E)-	-	CHEMSPIDER	86595640	C25H28Cl2N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IIKVQQNZHGBYGQ-KNTRCKAVSA-N
29935	116939	23358	hCG_33036	USP24	-	9606	Homo sapiens	inhibitor	target	Peterson LF (2015)	25814533	228677	9910	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide	(2E)-2-Cyano-3-(3,6-dichloro-2-pyridinyl)-N-(1-{4-[2-(4-morpholinyl)ethoxy]phenyl}butyl)acrylamide|2-Propenamide, 2-cyano-3-(3,6-dichloro-2-pyridinyl)-N-[1-[4-[2-(4-morpholinyl)ethoxy]phenyl]butyl]-, (2E)-	-	CHEMSPIDER	86595640	C25H28Cl2N4O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IIKVQQNZHGBYGQ-KNTRCKAVSA-N
29936	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Vu B (2013)	24900694	228678	8379	RG7112	RO-5045337|Q8MI0X869M|{(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}{4-[3-(methylsulfonyl)propyl]-1-piperazinyl}methanone|Methanone, [(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]-	-	CHEMSPIDER	28189760	C38H48Cl2N4O4S	small molecule	-	939981-39-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBGKPEROWUKSBK-QPPIDDCLSA-N
29937	113041	7189	-	TRAF6	MGC:3310|RNF85	9606	Homo sapiens	inhibitor	target	Brenke JK (2018)	29950522	216477	9880	C25-140	1-Propanone, 3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-|1-(4-Benzyl-1-piperidinyl)-3-[3,5-dimethyl-1-(3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-propanone	-	CHEMSPIDER	29053655	C26H31N7O	small molecule	-	1358099-18-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HFKVRXVHZGBRKF-UHFFFAOYSA-N
29938	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Myrianthopoulos V (2016)	27049577	195311	9904	NSC232003	(5Z)-5-[1-(Hydroxyamino)ethylidene]-2,4(3H,5H)-pyrimidinedione|2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-, (5Z)-	-	CHEMSPIDER	4513358	C6H7N3O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IXSSYZRLNVZFMP-ARJAWSKDSA-N
29939	124085	84447	-	SYVN1	DER3|HRD1	9606	Homo sapiens	inhibitor	target	Fujita H (2018)	30365055	218199	9844	LS-102	1,3,5-Triazine-2,4,6-triamine, N~4~-6-benzoxazolyl-N~6~-[(1S)-1-cyclohexylethyl]-N~2~-ethyl-N~2~-[2-(ethylamino)ethyl]-|N~4~-(1,3-Benzoxazol-6-yl)-N~6~-[(1S)-1-cyclohexylethyl]-N~2~-ethyl-N~2~-[2-(ethylamino)ethyl]-1,3,5-triazine-2,4,6-triamine	-	CHEMSPIDER	92169543	C24H36N8O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DEDHMXBDEJSZFE-KRWDZBQOSA-N
29940	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Reed D (2010)	20080970	228679	9926	SJ 172550	SJ 172550|MFCD03142926|SJ-172550|2-[2-Chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-acetic acid methyl ester|Methyl {2-chloro-6-ethoxy-4-[(Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]phenoxy}acetate|Acetic acid, 2-[2-chloro-4-[(Z)-(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-, methyl ester	-	CHEMSPIDER	1104430	C22H21ClN2O5	small molecule	-	431979-47-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RKKFQJXGAQWHBZ-YVLHZVERSA-N
29941	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Gu L (2016)	27666947	228680	9898	MX69	Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-|4-{8-[(3,4-Dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl}benzoic acid	-	CHEMSPIDER	3290554	C27H26N2O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XCBONKHCCRJMNW-UHFFFAOYSA-N
29942	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	inhibitor	target	Gu L (2016)	27666947	228680	9898	MX69	Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-|4-{8-[(3,4-Dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl}benzoic acid	-	CHEMSPIDER	3290554	C27H26N2O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XCBONKHCCRJMNW-UHFFFAOYSA-N
29943	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Wang S (2019)	30803229	219782	9901	WS-383	1H-Tetrazole-1-ethanamine, 5-[[2-[[(4-chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]thio]-N,N-dimethyl-, hydrochloride (1:1)|2-[5-({2-[(4-Chlorobenzyl)sulfanyl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)-1H-tetrazol-1-yl]-N,N-dimethylethanamine hydrochloride (1:1)	-	CHEMSPIDER	72380023	C18H21Cl2N9S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LJZUAAKUJAXXHQ-UHFFFAOYSA-N
29944	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24997575	228681	9839	RO8994	RO8994|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	31135025	C31H31Cl2FN4O4	small molecule	-	1309684-94-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MURAVORBGFDSMA-ISKXDESKSA-N
29945	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Karan G (2016)	26883273	228682	9865	Ctx1	9-Acridinecarbonitrile, 3,6-diamino-|3,6-Diamino-9-acridinecarbonitrile	-	CHEMSPIDER	384728	C14H10N4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PUMGFEMNXBLDKD-UHFFFAOYSA-N
29946	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Huang Y (2014)	24405416	228683	9841	YH239-EE	1H-Indole-2-carboxylic acid, 6-chloro-3-[1-[[(4-chlorophenyl)methyl]formylamino]-2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-, ethyl ester|Ethyl 6-chloro-3-{1-[(4-chlorobenzyl)(formyl)amino]-2-[(2-methyl-2-propanyl)amino]-2-oxoethyl}-1H-indole-2-carboxylate|YH239-EE|YH 239-EE	-	CHEMSPIDER	31042602	C25H27Cl2N3O4	small molecule	-	1364488-67-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTUBDDRFPQLPKD-UHFFFAOYSA-N
29947	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Porter JR (2010)	20856941	228684	9838	BH3I-1	BH3I-1|MFCD03453544|5-(p-Bromobenzylidine)-alpha-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic acid|3-Thiazolidineacetic acid, 5-[(4-bromophenyl)methylene]-alpha-(1-methylethyl)-4-oxo-2-thioxo-, (5E)-|2-[(5E)-5-(4-Bromobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-methylbutanoic acid	-	CHEMSPIDER	23291035	C15H14BrNO3S2	small molecule	-	300817-68-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	COHIEJLWRGREHV-YRNVUSSQSA-N
29948	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Chen R (2017)	28581721	228685	9751	Bivalent ligand 197	CG428|Bivalent_ligand_197	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	-	-	-	-	-	-	-	-	-	-
29949	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Gollner A (2016)	27775892	228686	9872	BI-0252	Benzoic acid, 4-[(3S,3'S,3a'S,5'R,6a'S)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-1,2,3',3'a,4',5',6',6'a-octahydro-2-oxospiro[3H-indole-3,2'(1'H)-pyrrolo[3,2-b]pyrrol]-5'-yl]-|4-[(3S,3'S,3a'S,5'R,6a'S)-6-Chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1,2,3',3a',4',5',6',6a'-octahydro-1'H-spiro[indole-3,2'-pyrrolo[3,2-b]pyrrol]-5'-yl]benzoic acid	-	CHEMSPIDER	59053072	C30H26Cl2FN3O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CCPUFNJKOGKOOG-AFKAWQRRSA-N
29950	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Wang S (2019)	30803229	219782	9869	2-[5-({2-[(4-Chlorobenzyl)sulfanyl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)-1H-tetrazol-1-yl]-N,N-dimethylethanamine	2-[5-({2-[(4-Chlorobenzyl)sulfanyl]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}sulfanyl)-1H-tetrazol-1-yl]-N,N-dimethylethanamine|1H-Tetrazole-1-ethanamine, 5-[[2-[[(4-chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]thio]-N,N-dimethyl-	-	CHEMSPIDER	84398507	C18H20ClN9S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MGESDQAAIJOGJA-UHFFFAOYSA-N
29951	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Zhou H (2017)	29074978	206893	9870	DI-591	N-[(1S)-1-Cyclohexyl-2-{[3-(4-morpholinyl)propanoyl]amino}ethyl]-3-(6-isopropyl-1,3-benzothiazol-2-yl)-N~2~-propionyl-L-alaninamide|2-Benzothiazolepropanamide, N-[(1S)-1-cyclohexyl-2-[[3-(4-morpholinyl)-1-oxopropyl]amino]ethyl]-6-(1-methylethyl)-alpha-[(1-oxopropyl)amino]-, (alphaS)-	-	CHEMSPIDER	88297468	C31H47N5O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CNJKDQGPBAWNRY-IZZNHLLZSA-N
29952	120504	55208	RP11-102K13.4	DCUN1D2	C13orf17	9606	Homo sapiens	inhibitor	target	Zhou H (2017)	29074978	206893	9870	DI-591	N-[(1S)-1-Cyclohexyl-2-{[3-(4-morpholinyl)propanoyl]amino}ethyl]-3-(6-isopropyl-1,3-benzothiazol-2-yl)-N~2~-propionyl-L-alaninamide|2-Benzothiazolepropanamide, N-[(1S)-1-cyclohexyl-2-[[3-(4-morpholinyl)-1-oxopropyl]amino]ethyl]-6-(1-methylethyl)-alpha-[(1-oxopropyl)amino]-, (alphaS)-	-	CHEMSPIDER	88297468	C31H47N5O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CNJKDQGPBAWNRY-IZZNHLLZSA-N
29953	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Wang W (2018)	30217928	228687	9860	MA242	Acetic acid, 2,2,2-trifluoro-, compd. with 7-[[(4-chlorophenyl)methyl]amino]-3,4-dihydro-1-[(4-methylphenyl)sulfonyl]pyrrolo[4,3,2-de]quinolin-8(1H)-one (1:1)|7-[(4-Chlorobenzyl)amino]-1-[(4-methylphenyl)sulfonyl]-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one trifluoroacetate (1:1)	-	CHEMSPIDER	75533946	C26H21ClF3N3O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YTSFRIUMZUCDMV-UHFFFAOYSA-N
29954	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Graves B (2012)	22745160	216713	9905	RO-5963	2-{(4E)-4-[(6-Chloro-7-methyl-1H-indol-3-yl)methylene]-2,5-dioxo-1-imidazolidinyl}-2-(3,4-difluorophenyl)-N-(1,3-dihydroxy-2-propanyl)acetamide|1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-alpha-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo-, (4E)-	-	CHEMSPIDER	75533987	C24H21ClF2N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZFYQBPVMECJUBO-FBCYGCLPSA-N
29955	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Graves B (2012)	22745160	216713	9905	RO-5963	2-{(4E)-4-[(6-Chloro-7-methyl-1H-indol-3-yl)methylene]-2,5-dioxo-1-imidazolidinyl}-2-(3,4-difluorophenyl)-N-(1,3-dihydroxy-2-propanyl)acetamide|1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-alpha-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo-, (4E)-	-	CHEMSPIDER	75533987	C24H21ClF2N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZFYQBPVMECJUBO-FBCYGCLPSA-N
29956	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Chen R (2017)	28581721	228685	9921	2-[4-({(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}carbonyl)-1-piperazinyl]-1-(4-morpholinyl)ethanone dihydrochloride	2-[4-({(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}carbonyl)-1-piperazinyl]-1-(4-morpholinyl)ethanone dihydrochloride|Ethanone, 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)-, hydrochloride (1:2)	-	CHEMSPIDER	35308372	C40H51Cl4N5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSDSITOZGWIHGA-IBBBAUQKSA-N
29957	113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	inhibitor	target	Ungermannova D (2012)	22274912	228688	9920	NSC 624206	N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride|Decylamine, N-(2-((p-chlorobenzyl)dithio)ethyl)-, hydrochloride|N-{2-[(4-Chlorobenzyl)disulfanyl]ethyl}-1-decanamine hydrochloride (1:1)|NSC 624206|1-Decanamine, N-[2-[[(4-chlorophenyl)methyl]dithio]ethyl]-, hydrochloride (1:1)|N-(2-((4-Chlorobenzyl)dithio)ethyl)-1-decanamine hydrochloride	-	CHEMSPIDER	320695	C19H33Cl2NS2	small molecule	-	13116-77-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JQHUAYXPNPTQRO-UHFFFAOYSA-N
29958	111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	inhibitor	target	Kazi A (2009)	19471122	228689	9918	PI-083	Benzenesulfonamide, 4-[(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-N-2-pyridinyl-|4-[(3-Chloro-1,4-dioxo-1,4-dihydro-2-naphthalenyl)amino]-N-(2-pyridinyl)benzenesulfonamide	-	CHEMSPIDER	209482	C21H14ClN3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QRPKNPKHGNUFGK-UHFFFAOYSA-N
29959	111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	inhibitor	target	Ho YK (2007)	17462577	228690	9919	MFCD17215971	DIHYDROEPONEMYCIN|MFCD17215971|N-[(2S)-3-Hydroxy-1-({(2S)-1-[(2R)-2-(hydroxymethyl)-2-oxiranyl]-4-methyl-1-oxo-2-pentanyl}amino)-1-oxo-2-propanyl]-6-methylheptanamide|Heptanamide, N-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)oxiranyl]carbonyl]-3-methylbutyl]amino]-2-oxoethyl]-6-methyl-	-	CHEMSPIDER	8267936	C20H36N2O6	small molecule	-	126463-64-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IUDBVFIQSSOIDB-TWOQFEAHSA-N
29960	111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	inhibitor	target	Ho YK (2007)	17462577	228690	9919	MFCD17215971	DIHYDROEPONEMYCIN|MFCD17215971|N-[(2S)-3-Hydroxy-1-({(2S)-1-[(2R)-2-(hydroxymethyl)-2-oxiranyl]-4-methyl-1-oxo-2-pentanyl}amino)-1-oxo-2-propanyl]-6-methylheptanamide|Heptanamide, N-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)oxiranyl]carbonyl]-3-methylbutyl]amino]-2-oxoethyl]-6-methyl-	-	CHEMSPIDER	8267936	C20H36N2O6	small molecule	-	126463-64-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IUDBVFIQSSOIDB-TWOQFEAHSA-N
29961	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9895	ML240	2-(2-Amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxy-4-quinazolinamine|ML240|CID-49830258|MFCD28137687|ML-240|2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine|4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-	-	CHEMSPIDER	34500429	C23H20N6O	small molecule	-	1346527-98-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NHAMBLRUUJAFOY-UHFFFAOYSA-N
29962	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9887	LC-1028	N-{1-[(4Z)-4-(Benzylimino)-3,4,5,6,7,8-hexahydro-2-quinazolinyl]-2-methyl-1H-indol-4-yl}-2-butynamide|2-Butynamide, N-[1-[(4Z)-3,4,5,6,7,8-hexahydro-4-[(phenylmethyl)imino]-2-quinazolinyl]-2-methyl-1H-indol-4-yl]-	-	CHEMSPIDER	88296358	C28H27N5O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YOUVOKAIDVNCJA-UHFFFAOYSA-N
29963	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9854	UPCDC30245	1-[3-(5-Fluoro-1H-indol-2-yl)phenyl]-N-[2-(4-isopropyl-1-piperazinyl)ethyl]-4-piperidinamine|1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)-|1-(3-(5-Fluoro-1h-Indol-2-Yl)phenyl)piperidin-4-Yl)(2-(4-Isopropyl-Piperazin1-Yl)ethyl)-Carbamate|1-(3-(5-Fluoro-1H-indol-2-yl)phenyl)-N-(2-(4-isopropylpiperazin-1-yl)ethyl)piperidin-4-amine|UPCDC30245	-	CHEMSPIDER	58825106	C28H38FN5	small molecule	-	1883351-01-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZHXZCVDLATFAR-UHFFFAOYSA-N
29964	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Alverez C (2016)	26985295	195724	9879	SMDC818909	3-Amino-N-(2-methyl-1H-indol-5-yl)-2-pyrazinecarboxamide|2-Pyrazinecarboxamide, 3-amino-N-(2-methyl-1H-indol-5-yl)-	-	CHEMSPIDER	30141951	C14H13N5O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PJTNJJWGQNSQDQ-UHFFFAOYSA-N
29965	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Alverez C (2016)	26985295	195724	9849	2-Amino-N-(2-methyl-1H-indol-5-yl)nicotinamide	3-Pyridinecarboxamide, 2-amino-N-(2-methyl-1H-indol-5-yl)-|2-Amino-N-(2-methyl-1H-indol-5-yl)nicotinamide	-	CHEMSPIDER	75831997	C15H14N4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GWHPATATCVJNBI-UHFFFAOYSA-N
29966	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9932	Eeyarestatin 1	Eeyarestatin I|3-(4-Chlorophenyl)-1-[3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitro-2-furyl)prop-2-en-1-ylidene]hydrazino}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-1-hydroxyurea|1-Imidazolidineacetic acid, 3-(4-chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-, 2-[(1E,2E)-3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide|3-(4-Chlorophenyl)-1-[3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazino}-2-oxoethyl)-2-oxo-4-imidazolidinyl]-1-hydroxyurea|Eeyarestatin 1	-	CHEMSPIDER	24606066	C27H25Cl2N7O7	small molecule	-	412960-54-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JTUXTPWYZXWOIB-LWWHHIEBSA-N
29967	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	250	Clotrimazole	Mycelex (tn)|1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole|Clotrimazole|1-(o-Chlorotrityl)imidazole|Lotrimin (tn)|1-(-(2-Chlorophenyl)benzhydryl)imidazole|1-(o-Chloro-,-diphenylbenzyl)imidazole|1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole|1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole	myclo solution|clotrimazole ex	DRUGBANK	DB00257	C22H17ClN2	small molecule	A01AB18|G01AF02|D01AC01	23593-75-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VNFPBHJOKIVQEB-UHFFFAOYSA-N
29968	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	627	Astemizole	Astemizolum|1-(P-Fluorobenzyl)-2-((1-(P-methoxyphenethyl)-4-piperidyl)amino)benzimidazole|1-(P-Fluorobenzyl)-2-((1-(2-(P-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole|Astemison|Astmizole|Astemizol	hismanal tab 10mg|hismanal sus	DRUGBANK	DB00637	C28H31FN4O	small molecule	R06AX11	68844-77-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXDALQBWZGODGZ-UHFFFAOYSA-N
29969	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	9907	Ebastine	Ebastine|1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone|4'-tert-Butyl-4-[4-(diphenylmethoxy)piperidino]butyrophenone|4-Diphenylmethoxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine|4-[4-(Diphenylmethoxy)-1-piperidinyl]-1-[4-(2-methyl-2-propanyl)phenyl]-1-butanone|1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-|1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one|Ebastin|MFCD00865661	-	CHEMSPIDER	3079	C32H39NO2	small molecule	-	90729-43-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJJALKDDGIKVBE-UHFFFAOYSA-N
29970	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Wijeratne EM (2016)	26812276	228693	9897	Oxaspirol B	2-Oxaspiro[4.5]dec-7-ene-1,4-dione, 6-[(1E,3E)-1,3-heptadien-1-yl]-9,10-dihydroxy-3-methylene-, (6R,9R,10R)-|(6R,9R,10R)-6-[(1E,3E)-1,3-Heptadien-1-yl]-9,10-dihydroxy-3-methylene-2-oxaspiro[4.5]dec-7-ene-1,4-dione	-	CHEMSPIDER	58927941	C17H20O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GIXMLHVPEUCNBI-VRRHEOGASA-N
29971	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Suvarna K (2019)	30610116	228694	9856	NPD8733	N-[2-(4-Methoxybenzoyl)-1-benzofuran-3-yl]acetamide|Acetamide, N-[2-(4-methoxybenzoyl)-3-benzofuranyl]-	-	CHEMSPIDER	792712	C18H15NO4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NQZBUYPGHZTWIR-UHFFFAOYSA-N
29972	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	inhibitor	target	Blees JS (2012)	23056346	146614	9874	Erioflorin	2-Propenoic acid, 2-methyl-, (1aR,3S,4E,5aR,8aR,9R,10aR)-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-3-hydroxy-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester|(1aR,3S,4E,5aR,8aR,9R,10aR)-3-Hydroxy-4,10a-dimethyl-8-methylene-7-oxo-1a,2,3,5a,7,8,8a,9,10,10a-decahydrooxireno[5,6]cyclodeca[1,2-b]furan-9-yl methacrylate	-	CHEMSPIDER	4530237	C19H24O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BUIOBTSUIYLOKG-VKGAXADOSA-N
29973	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
29974	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
29975	124238	84749	-	USP30	-	9606	Homo sapiens	inhibitor	target	Yue W (2014)	24513856	228695	9846	15-Oxospiramilactone	8a,11-Ethano-6,12b-propano-9H-naphth[1,2-d]oxocin-1,9(2H)-dione, decahydro-8-hydroxy-6-methyl-10-methylene-, (6S,6aR,8R,8aR,11S,12aS,12bS)-|15-oxospiramilactone|(1S,2S,4S,7R,8R,10R,11S)-8-Hydroxy-11-methyl-5-methylene-14-oxapentacyclo[9.5.3.2~4,7~.0~1,10~.0~2,7~]henicosane-6,16-dione	-	CHEMSPIDER	65321854	C22H30O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RCPPZYXWUAJXMA-KGYWYPJXSA-N
29976	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	821	Trifluoperazine	10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine|10-[3-(4-METHYL-piperazin-1-yl)-propyl]-2-trifluoromethyl-10H-phenothiazine|Trifluoroperazine|Trifluoperazinum|Trifluoperazina|Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine|Trifluperazine|Trifluoperazine	pms trifluoperazine hcl syrup 	DRUGBANK	DB00831	C21H24F3N3S	small molecule	N05AB06	117-89-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZEWQUBUPAILYHI-UHFFFAOYSA-N
29977	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	821	Trifluoperazine	10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine|10-[3-(4-METHYL-piperazin-1-yl)-propyl]-2-trifluoromethyl-10H-phenothiazine|Trifluoroperazine|Trifluoperazinum|Trifluoperazina|Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine|Trifluperazine|Trifluoperazine	pms trifluoperazine hcl syrup 	DRUGBANK	DB00831	C21H24F3N3S	small molecule	N05AB06	117-89-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZEWQUBUPAILYHI-UHFFFAOYSA-N
29978	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29979	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29980	113194	7347	RP11-173B14.3	UCHL3	UCH-L3	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29981	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29982	128522	219333	-	USP12	UBH1|USP12L1	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29983	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9916	SJB3-019A	Naphth[2,3-d]oxazole-4,9-dione, 2-(3-pyridinyl)-|2-(3-Pyridinyl)naphtho[2,3-d][1,3]oxazole-4,9-dione	-	CHEMSPIDER	44208868	C16H8N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOYPPVCQHGJUBC-UHFFFAOYSA-N
29984	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Magiera K (2017)	28343940	228696	9859	LCAHA	Cholan-24-amide, N,3-dihydroxy-, (3alpha)-|(3alpha)-N,3-Dihydroxycholan-24-amide	-	CHEMSPIDER	88297896	C24H41NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WZXAGWREMCSWMF-YPLGJCPNSA-N
29985	112373	6478	-	SIAH2	hSiah2	9606	Homo sapiens	inhibitor	target	Shah M (2009)	19712206	228697	163	Menadione	Menadione|Vitamin K3|2-Methyl-1,4-naphthochinon|2-Methyl-1,4-Naphthalenedione|2-Methyl-1,4-naphthoquinone	-	DRUGBANK	DB00170	C11H8O2	small molecule	B02BA02	58-27-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJVAVZPDRWSRRC-UHFFFAOYSA-N
29986	112372	6477	-	SIAH1	SIAH1A	9606	Homo sapiens	inhibitor	target	Zhang Q (2017)	27776223	199360	163	Menadione	Menadione|Vitamin K3|2-Methyl-1,4-naphthochinon|2-Methyl-1,4-Naphthalenedione|2-Methyl-1,4-naphthoquinone	-	DRUGBANK	DB00170	C11H8O2	small molecule	B02BA02	58-27-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJVAVZPDRWSRRC-UHFFFAOYSA-N
29987	112373	6478	-	SIAH2	hSiah2	9606	Homo sapiens	inhibitor	target	Zhang Q (2017)	27776223	199360	163	Menadione	Menadione|Vitamin K3|2-Methyl-1,4-naphthochinon|2-Methyl-1,4-Naphthalenedione|2-Methyl-1,4-naphthoquinone	-	DRUGBANK	DB00170	C11H8O2	small molecule	B02BA02	58-27-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJVAVZPDRWSRRC-UHFFFAOYSA-N
29988	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Schauer NJ (2020)	31682427	228698	9906	NSC632839	4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, (3E)-, hydrochloride (1:1)|(3E)-3,5-Bis(4-methylbenzylidene)-4-piperidinone hydrochloride (1:1)	-	CHEMSPIDER	57427760	C21H22ClNO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZOKZLTXPTLIWOJ-OJWWICQKSA-N
29989	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Schauer NJ (2020)	31682427	228698	9906	NSC632839	4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, (3E)-, hydrochloride (1:1)|(3E)-3,5-Bis(4-methylbenzylidene)-4-piperidinone hydrochloride (1:1)	-	CHEMSPIDER	57427760	C21H22ClNO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZOKZLTXPTLIWOJ-OJWWICQKSA-N
29990	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Schauer NJ (2020)	31682427	228698	9902	Spongiacidin A	Pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-5-oxo-4-imidazolidinylidene)-2,3-dibromo-4,5,6,7-tetrahydro-, (4E)-|(4E)-4-(2-Amino-5-oxo-4-imidazolidinylidene)-2,3-dibromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one	-	CHEMSPIDER	24699820	C11H11Br2N5O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CTHGIINQRBTFRV-ZZXKWVIFSA-N
29991	113867	8239	RP5-1172N10.4	USP9X	DFFRX|FAF|FAM|MRX99	9606	Homo sapiens	inhibitor	target	Peng Z (2014)	24457091	228699	9903	CP2005	2-Propenamide, N,N'-[1,3-phenylenebis(methylene)]bis[3-(6-bromo-2-pyridinyl)-2-cyano-, (2Z,2'Z)-|(2Z,2'Z)-N,N'-[1,3-Phenylenebis(methylene)]bis[3-(6-bromo-2-pyridinyl)-2-cyanoacrylamide]	-	CHEMSPIDER	31138442	C26H18Br2N6O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTSJSSHNIUCAGH-YZLQMOBTSA-N
29992	114977	9616	-	RNF7	CKBBP1|ROC2|SAG	9606	Homo sapiens	inhibitor	target	Yu Q (2020)	32145688	226735	9858	Gossypol	N,N,1,3-Tetramethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine|1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N,N,1,3-tetramethyl-|Dipotassium Salt|Sodium Salt|BL193|ssypol|AT101|TASH1|POGOSIN	-	CHEMSPIDER	32145688	C30H30O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBKSWRVVCFFDOT-UHFFFAOYSA-N
29993	115301	9978	RP11-554C12.1	RBX1	BA554C12.1|RNF75|ROC1	9606	Homo sapiens	inhibitor	target	Yu Q (2020)	32145688	226735	9858	Gossypol	N,N,1,3-Tetramethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine|1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N,N,1,3-tetramethyl-|Dipotassium Salt|Sodium Salt|BL193|ssypol|AT101|TASH1|POGOSIN	-	CHEMSPIDER	32145688	C30H30O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBKSWRVVCFFDOT-UHFFFAOYSA-N
29994	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Scott DC (2017)	28581483	211304	9853	NAcM-HIT	Urea, N-[1-(phenylmethyl)-4-piperidinyl]-N'-[3-(trifluoromethyl)phenyl]-|1-(1-Benzyl-4-piperidinyl)-3-[3-(trifluoromethyl)phenyl]urea	-	CHEMSPIDER	3073302	C20H22F3N3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MXZRHPHRSQJCML-UHFFFAOYSA-N
29995	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Scott DC (2017)	28581483	211304	9933	NAcM-OPT	Urea, N-(1-butyl-4-piperidinyl)-N'-(3,4-dichlorophenyl)-N-(phenylmethyl)-|1-Benzyl-1-(1-butyl-4-piperidinyl)-3-(3,4-dichlorophenyl)urea	-	CHEMSPIDER	59052433	C23H29Cl2N3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VPHJABWIKCBGMC-UHFFFAOYSA-N
29996	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Kim HS (2019)	31465221	228079	9890	3-Methyl-N-[(4S,5R)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide	Benzamide, 3-methyl-N-[(4S,5R)-4,5,6,7-tetrahydro-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl]-|3-Methyl-N-[(4S,5R)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide	-	CHEMSPIDER	78310128	C28H26N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	This small molecule corresponds to Compound 1 in this paper.	WMAFBTHYXHDENE-LOSJGSFVSA-N
29997	119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	inhibitor	target	Kim HS (2019)	31465221	228079	9935	N-[1-[4-(Aminomethyl)-3-methylsulfonylphenyl]but-3-en-2-yl]-5-[[(2S)-2-azido-3-phenylpropanoyl]amino]-2-(2-methylpropyl)-4-oxooctanamide	N-[1-[4-(Aminomethyl)-3-methylsulfonylphenyl]but-3-en-2-yl]-5-[[(2S)-2-azido-3-phenylpropanoyl]amino]-2-(2-methylpropyl)-4-oxooctanamide|N3Phe-Leu-Leu-Phe(4-CH2NH2)VS|azido-phenylalanyl-leucyl-leucyl-4-aminomethylphenylalanyl methyl vinyl sulfone|azido-Phe-Leu-Leu-4-aminomethyl-Phe-methyl vinyl sulfone|N-[(4S,5S)-1-[(1S)-Cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5-dihydropyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide	-	PUBCHEM	145946100	C29H31FN4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	This small molecule corresponds to Compound 27 in this paper.	DRGYLPYZJGVISN-AFESJLNVSA-N
30005	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Turnbull AP (2017)	29045389	220338	9882	FT827	Ethenesulfonamide, N-[4'-[[4-[(1,4-dihydro-1-methyl-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-4-hydroxy-1-piperidinyl]carbonyl][1,1'-biphenyl]-2-yl]-|N-[4'-({4-Hydroxy-4-[(1-methyl-4-oxo-1,4-dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-1-piperidinyl}carbonyl)-2-biphenylyl]ethenesulfonamide	-	CHEMSPIDER	71117270	C27H28N6O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFNJQQBUZURQMA-UHFFFAOYSA-N
30006	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu M (2020)	33163345	228700	9771	Bivalent ligand 172	compound 2c|Bivalent_ligand_172	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109832	3620	-	IDO1	IDO|IDO-1|INDO	9606	Homo sapiens	target	Standardized BVL Name: compuound 2c (CRBN:lenalidomide --- IDO1:Epa)	-
30008	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Z (2020)	32779949	228701	9770	Bivalent ligand 173	compound 2|Bivalent_ligand_173	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: compound 2 (CRBN:lenalidomide --- PARP1: Olaparib)	-
30010	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2020)	32128407	228702	9767	Bivalent ligand 174	opto-dBET1|Bivalent_ligand_174	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: opto-dBET1 (CRBN:opto-pomalidomide --- BRD2:JQ1)	-
30012	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2020)	32128407	228702	9767	Bivalent ligand 174	opto-dBET1|Bivalent_ligand_174	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: opto-dBET1 (CRBN:opto-pomalidomide --- BRD3:JQ1)	-
30014	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2020)	32128407	228702	9767	Bivalent ligand 174	opto-dBET1|Bivalent_ligand_174	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: opto-dBET1 (CRBN:opto-pomalidomide --- BRD4:JQ1)	-
30016	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2020)	32128407	228702	9766	Bivalent ligand 175	opto-dALK|Bivalent_ligand_175	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: opto-dALK(CRBN:opto-pomalidomide --- ALK:ceritinib)	-
30018	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2020)	32128406	228703	9769	Bivalent ligand 176	PHOTAC-I-3|Bivalent_ligand_176	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD2:JQ1)	-
30020	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2020)	32128406	228703	9769	Bivalent ligand 176	PHOTAC-I-3|Bivalent_ligand_176	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD3:JQ1)	-
30022	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2020)	32128406	228703	9769	Bivalent ligand 176	PHOTAC-I-3|Bivalent_ligand_176	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
30024	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2020)	32128406	228703	9768	Bivalent ligand 177	PHOTAC-II-6|Bivalent_ligand_177	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-II-6 (CRBN:thalidomide --- FKBP12:SLF)	-
30026	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Si J (2020)	32860752	228704	9777	Bivalent ligand 178	SS44|Bivalent_ligand_178	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: SS44 (CRBN:thalidomide --- MAPK41: ZYF0033)	-
30028	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang J (2020)	32888499	228705	9776	Bivalent ligand 179	Degrader-5|Bivalent_ligand_179	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: Degrader-5 (CRBN:thalidomide --- IRAK4: compound 1)	-
30030	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cao C (2020)	32924477	228706	9800	Bivalent ligand 180	SK-575|Bivalent_ligand_180	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: SK-575 (CRBN:thalidomide --- PARP1: Olaparib)	-
30032	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Takahashi D (2020)	31958028	228707	9801	Bivalent ligand 181	ARD-61|Bivalent_ligand_181	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-61 (VHL:HXD079 --- AR:ARi-16)	-
30034	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Takahashi D (2020)	31958028	228707	9801	Bivalent ligand 181	ARD-61|Bivalent_ligand_181	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111260	5241	-	PGR	NR3C3|PR	9606	Homo sapiens	target	Standardized BVL Name: ARD-61 (VHL:HXD079 --- PR:ARi-16)	-
30036	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Takwale AD (2020)	32961381	228708	9802	Bivalent ligand 182	TD-802|Bivalent_ligand_182	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: TD-802 (CRBN:TD-106 --- AR:compound 3)	-
30038	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	9803	Bivalent ligand 183	SJFDelta|Bivalent_ligand_183	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111589	5603	RP1-179N16.4	MAPK13	MAPK 13|MAPK-13|PRKM13|SAPK4|p38delta	9606	Homo sapiens	target	Standardized BVL Name: SJF (VHL:ligand 7 ---MAPK13:Foretinib)	-
30040	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111589	5603	RP1-179N16.4	MAPK13	MAPK 13|MAPK-13|PRKM13|SAPK4|p38delta	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2 (CRBN:CRBN ligand --- MAPK13:foretinib)|Standardized BVL Name: PROTAC2 (CRBN:CRBN ligand --- MERTK:foretinib)	-
30042	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen H (2019)	30901674	215477	9796	Bivalent ligand 184	Compound 2|Bivalent_ligand_184	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: Compound 2 (CRBN:pomalidomide --- BRAF: rigosertib)	-
30044	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	An Z (2019)	30603959	228709	9798	Bivalent ligand 186	PROTAC NP8|Bivalent_ligand_186	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: PROTAC NP8 (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
30046	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu H (2019)	31271281	228479	9797	Bivalent ligand 185	PROTAC 12d|Bivalent_ligand_185	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 12d (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
30048	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu H (2019)	31271281	228479	9797	Bivalent ligand 185	PROTAC 12d|Bivalent_ligand_185	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 12d (CRBN:pomalidomide --- IKZF1:Nexturastat A (Nex A))	-
30050	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu H (2019)	31271281	228479	9797	Bivalent ligand 185	PROTAC 12d|Bivalent_ligand_185	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 12d (CRBN:pomalidomide --- IKZF3:Nexturastat A (Nex A))	-
30052	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	degradation	recruited e3 ligase	Du X (2019)	31693911	222755	9805	Bivalent ligand 188	Bivalent_ligand_188	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114952	9584	RP11-353C18.2	RBM39	CAPER|CAPERalpha|FSAP59|HCC1|RNPC2	9606	Homo sapiens	target	Standardized BVL Name: (DCAF15:E7820 ---RBM39:E7820)	-
30054	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	degradation	recruited e3 ligase	Han T (2017)	28302793	209322	9806	Bivalent ligand 189	Bivalent_ligand_189	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114952	9584	RP11-353C18.2	RBM39	CAPER|CAPERalpha|FSAP59|HCC1|RNPC2	9606	Homo sapiens	target	Standardized BVL Name: (DCAF15:indisulam ---RBM39:indisulam)	-
30056	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	degradation	recruited e3 ligase	Han T (2017)	28302793	209322	9758	Bivalent ligand 190	Bivalent_ligand_190	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114952	9584	RP11-353C18.2	RBM39	CAPER|CAPERalpha|FSAP59|HCC1|RNPC2	9606	Homo sapiens	target	Standardized BVL Name: (DCAF15:tasisulam ---RBM39:tasisulam)	-
30058	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	degradation	recruited e3 ligase	Han T (2017)	28302793	209322	9757	Bivalent ligand 191	Bivalent_ligand_191	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114952	9584	RP11-353C18.2	RBM39	CAPER|CAPERalpha|FSAP59|HCC1|RNPC2	9606	Homo sapiens	target	Standardized BVL Name: (DCAF15:chloroquinoxaline sulfonamide ---RBM39:chloroquinoxaline sulfonamide)	-
30060	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bassi ZI (2018)	30200762	228710	9799	Bivalent ligand 187	GSK699|Bivalent_ligand_187	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108918	2648	-	KAT2A	GCN5|GCN5L2|PCAF-b|hGCN5	9606	Homo sapiens	target	Standardized BVL Name: GSK699 (CRBN:thalidomide --- KAT2A:GSK4027)	-
30062	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bassi ZI (2018)	30200762	228710	9799	Bivalent ligand 187	GSK699|Bivalent_ligand_187	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	target	Standardized BVL Name: GSK699 (CRBN:thalidomide --- KAT2B:GSK4027)	-
30064	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- ALK:TAE684)	-
30066	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- AURKA:TAE684)	-
30068	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- RPS6KA1:TAE684)	-
30070	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- PTK2:TAE684)	-
30072	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- FER:TAE684)	-
30074	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- ALK:ceritinib)	-
30076	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- AURKA:ceritinib)	-
30078	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- RPS6KA1:ceritinib)	-
30080	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- PTK2:ceritinib)	-
30082	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- FER:ceritinib)	-
30084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121316	57001	DC11	ACN9	SDHAF3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- SDHAF3:foretinib)	-
30086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121596	57537	-	SORCS2	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- SORCS2:foretinib)	-
30088	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108474	2177	-	FANCD2	FA-D2|FA4|FACD|FAD|FAD2|FANCD	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- FANCD2:foretinib)	-
30090	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116553	22887	-	FOXJ3	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- FOXJ3:foretinib)	-
30092	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107851	1469	-	CST1	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2 (CRBN:CRBN ligand --- CST1:foretinib)	-
30094	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Girardini M (2019)	30826187	220662	9754	Bivalent ligand 194	PROTAC 14a|Bivalent_ligand_194	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 14a (VHL:VH032 ---CRBN:pomalidomide	-
30096	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Girardini M (2019)	30826187	220662	9753	Bivalent ligand 195	PROTAC 18b|Bivalent_ligand_195	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 18b (VHL:VH101 ---CRBN:pomalidomide)	-
30098	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9752	Bivalent ligand 196	CG416|Bivalent_ligand_196	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110969	4914	-	NTRK1	MTC|TRK|TRK1|TRKA|Trk-A|p140-TrkA	9606	Homo sapiens	target	Standardized BVL Name: CG416 (CRBN:pomalidomide --- NTRK1:GNF-8625)	-
30100	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9752	Bivalent ligand 196	CG416|Bivalent_ligand_196	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110970	4915	RP11-263K15.1	NTRK2	GP145-TrkB|TRKB|trk-B	9606	Homo sapiens	target	Standardized BVL Name: CG416 (CRBN:pomalidomide --- NTRK2:GNF-8625)	-
30102	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9752	Bivalent ligand 196	CG416|Bivalent_ligand_196	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110971	4916	-	NTRK3	TRKC|gp145(trkC)	9606	Homo sapiens	target	Standardized BVL Name: CG416 (CRBN:pomalidomide --- NTRK3:GNF-8625)	-
30104	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9751	Bivalent ligand 197	CG428|Bivalent_ligand_197	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110969	4914	-	NTRK1	MTC|TRK|TRK1|TRKA|Trk-A|p140-TrkA	9606	Homo sapiens	target	Standardized BVL Name: CG428 (CRBN:pomalidomide --- NTRK1:GNF-8625)	-
30106	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9751	Bivalent ligand 197	CG428|Bivalent_ligand_197	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110970	4915	RP11-263K15.1	NTRK2	GP145-TrkB|TRKB|trk-B	9606	Homo sapiens	target	Standardized BVL Name: CG428 (CRBN:pomalidomide --- NTRK2:GNF-8625)	-
30108	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen L (2020)	33058680	228712	9751	Bivalent ligand 197	CG428|Bivalent_ligand_197	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110971	4916	-	NTRK3	TRKC|gp145(trkC)	9606	Homo sapiens	target	Standardized BVL Name: CG428 (CRBN:pomalidomide --- NTRK3:GNF-8625)	-
30110	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9762	Bivalent ligand 198	compound 1|Bivalent_ligand_198	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 1 (VHL:VHL-1 --- SNCA:BTA-1)	-
30112	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9761	Bivalent ligand 199	compound 4|Bivalent_ligand_199	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL-1 --- SNCA:BTA-1)	-
30114	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9787	Bivalent ligand 200	compound 5|Bivalent_ligand_200	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (VHL:VHL-1 --- SNCA:BTA-1)	-
30116	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9786	Bivalent ligand 201	compound 7|Bivalent_ligand_201	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30118	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9785	Bivalent ligand 202	compound 34|Bivalent_ligand_202	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 34 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30120	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9784	Bivalent ligand 203	compound 30|Bivalent_ligand_203	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 30 (CRBN:thalidomide --- SNCA:SNCA ligand)	-
30122	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou L (2020)	31945665	228714	9783	Bivalent ligand 204	6C|Bivalent_ligand_204	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107925	1545	-	CYP1B1	CP1B|CYPIB1|GLC3A|P4501B1	9606	Homo sapiens	target	Standardized BVL Name: 6C (CRBN:thalidomide --- CYP1B1:-naphthoflavone derivative 5)	-
30124	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9782	Bivalent ligand 205	JP1|Bivalent_ligand_205	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP1 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30126	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9781	Bivalent ligand 206	JP2|Bivalent_ligand_206	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP2 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30128	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9780	Bivalent ligand 207	JP3|Bivalent_ligand_207	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP3 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30130	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9795	Bivalent ligand 208	JP4|Bivalent_ligand_208	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP4 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30132	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9794	Bivalent ligand 209	JP5|Bivalent_ligand_209	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP5 (XIAP:Boc-IAP --- JAK1:quinoxaline)	-
30134	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9824	Bivalent ligand 210	JP6|Bivalent_ligand_210	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: JP6 (XIAP:Boc-IAP --- JAK1:quinoxaline)	-
30136	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9782	Bivalent ligand 205	JP1|Bivalent_ligand_205	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP1 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30138	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9781	Bivalent ligand 206	JP2|Bivalent_ligand_206	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP2 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30140	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9780	Bivalent ligand 207	JP3|Bivalent_ligand_207	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP3 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30142	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9795	Bivalent ligand 208	JP4|Bivalent_ligand_208	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP4 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30144	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9794	Bivalent ligand 209	JP5|Bivalent_ligand_209	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP5 (XIAP:Boc-IAP --- JAK2:quinoxaline)	-
30146	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Shah RR (2020)	32001089	227145	9824	Bivalent ligand 210	JP6|Bivalent_ligand_210	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: JP6 (XIAP:Boc-IAP --- JAK2:quinoxaline)	-
30148	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EED: EED ligand)	-
30150	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EED: EED ligand)	-
30152	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EZH2: EED ligand)	-
30154	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EZH2: EED ligand)	-
30156	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- SUZ12: EED ligand)	-
30158	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- SUZ12: EED ligand)	-
30160	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	You I (2020)	31859249	224930	9827	Bivalent ligand 213	INY-03-041|Bivalent_ligand_213	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041 (CRBN:lenalidomide --- AKT1:GDC-0068)	-
30162	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	You I (2020)	31859249	224930	9827	Bivalent ligand 213	INY-03-041|Bivalent_ligand_213	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041 (CRBN:lenalidomide --- AKT2:GDC-0068)	-
30164	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	You I (2020)	31859249	224930	9827	Bivalent ligand 213	INY-03-041|Bivalent_ligand_213	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041 (CRBN:lenalidomide --- AKT3:GDC-0068)	-
30166	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao B (2019)	31512882	228715	9820	Bivalent ligand 214	IYx96IY-pom (4)|Bivalent_ligand_214	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110971	4916	-	NTRK3	TRKC|gp145(trkC)	9606	Homo sapiens	target	Standardized BVL Name: IYIY-pom (4) (CRBN:pomalidomide --- NTRK3: IY-IY-TEG)	-
30168	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li MX (2020)	32321253	228716	9821	Bivalent ligand 215	P22A|Bivalent_ligand_215	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109399	3156	-	HMGCR	LDLCQ3	9606	Homo sapiens	target	Standardized BVL Name: P22A (CRBN:pomalidomide --- HMGCR:Atorvastatin)	-
30170	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30172	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30174	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- HDAC1-FKBP12F36V:AP1867)	-
30176	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- HDAC1-FKBP12F36V:AP1867)	-
30178	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	target	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- MYC-FKBP12F36V:AP1867)	-
30180	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	target	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- MYC-FKBP12F36V:AP1867)	-
30182	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- PLK1-FKBP12F36V:AP1867)	-
30184	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- PLK1-FKBP12F36V:AP1867)	-
30186	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30188	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30190	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112401	6510	-	SLC1A5	AAAT|ASCT2|ATBO|M7V1|M7VS1|R16|RDRC	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC1A5-FKBP12F36V:AP1867)	-
30192	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112406	6515	-	SLC2A3	GLUT3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC2A3-FKBP12F36V:AP1867)	-
30194	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123509	81539	-	SLC38A1	ATA1|NAT2|SAT1|SNAT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC38A1-FKBP12F36V:AP1867)	-
30196	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112404	6513	-	SLC2A1	DYT17|DYT18|DYT9|EIG12|GLUT|GLUT-1|GLUT1|GLUT1DS|HTLVR|PED	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC2A1-FKBP12F36V:AP1867)	-
30198	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112438	6548	RP4-633N17.1	SLC9A1	APNH|NHE-1|NHE1|PPP1R143	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC9A15-FKBP12F36V:AP1867)	-
30200	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112454	6566	RP4-580L15.1	SLC16A1	HHF7|MCT|MCT1|MCT1D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC16A1-FKBP12F36V:AP1867)	-
30202	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113652	7922	DADB-100D22.3	SLC39A7	D6S115E|D6S2244E|H2-KE4|HKE4|KE4|RING5|ZIP7	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC39A7-FKBP12F36V:AP1867)	-
30204	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115726	10463	-	SLC30A9	C4orf1|GAC63|HUEL|ZNT9	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC30A9-FKBP12F36V:AP1867)	-
30206	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	131484	347734	RP1-302G2.3	SLC35B2	PAPST1|SLL|UGTrel4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC35B2-FKBP12F36V:AP1867)	-
30208	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114632	9197	-	SLC33A1	ACATN|AT-1|AT1|CCHLND|SPG42	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC33A1-FKBP12F36V:AP1867)	-
30210	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127480	153129	-	SLC38A9	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC38A9-FKBP12F36V:AP1867)	-
30212	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119943	54407	-	SLC38A2	ATA2|PRO1068|SAT2|SNAT2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC38A2-FKBP12F36V:AP1867)	-
30214	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9833	Bivalent ligand 219	iRucaparib-TP3|Bivalent_ligand_219	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-TP3 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30216	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9789	Bivalent ligand 220	iRucaparib-TP4|Bivalent_ligand_220	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-TP4 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30218	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9788	Bivalent ligand 221	vRucaparib-TP3|Bivalent_ligand_221	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: vRucaparib-TP3 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30220	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9791	Bivalent ligand 222	vRucaparib-TP4|Bivalent_ligand_222	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: vRucaparib-TP4 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30222	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9790	Bivalent ligand 223	iRucaparib-AP5|Bivalent_ligand_223	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-AP5 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30224	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9793	Bivalent ligand 224	iRucaparib-AP6|Bivalent_ligand_224	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-AP6 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30226	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9792	Bivalent ligand 225	iVeliparib-AP6|Bivalent_ligand_225	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115350	10038	-	PARP2	ADPRT2|ADPRTL2|ADPRTL3|ARTD2|PARP-2|pADPRT-2	9606	Homo sapiens	target	Standardized BVL Name: iVeliparib-AP6 (CRBN:pomalidomide --- PARP1:Veliparib)	-
30228	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9790	Bivalent ligand 223	iRucaparib-AP5|Bivalent_ligand_223	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-AP5 (CRBN:pomalidomide --- PARP3:Rucaparib)	-
30230	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9793	Bivalent ligand 224	iRucaparib-AP6|Bivalent_ligand_224	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	target	Standardized BVL Name: iRucaparib-AP6 (CRBN:pomalidomide --- PARP3:Rucaparib)	-
30232	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Manda S (2020)	32340152	228719	9818	Bivalent ligand 256	CPR3|Bivalent_ligand_256	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109701	3480	-	IGF1R	CD221|IGFIR|IGFR|JTK13	9606	Homo sapiens	target	Standardized BVL Name: CPR3 (CRBN:pomalidomide --- IGF1R:RBx10080307)	-
30234	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Manda S (2020)	32340152	228719	9831	Bivalent ligand 226	CPR4|Bivalent_ligand_226	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109701	3480	-	IGF1R	CD221|IGFIR|IGFR|JTK13	9606	Homo sapiens	target	Standardized BVL Name: CPR4 (CRBN:pomalidomide --- IGF1R:RBx10080307)	-
30236	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Manda S (2020)	32340152	228719	9818	Bivalent ligand 256	CPR3|Bivalent_ligand_256	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: CPR3 (CRBN:pomalidomide --- Src:RBx10080307)	-
30238	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Manda S (2020)	32340152	228719	9831	Bivalent ligand 226	CPR4|Bivalent_ligand_226	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: CPR4 (CRBN:pomalidomide --- Src:RBx10080307)	-
30240	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ishoey M (2018)	29356495	228720	9808	Bivalent ligand 227	MI-389|Bivalent_ligand_227	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: MI-389 (CRBN:phthalimide --- GSPT1:sunitinib)	-
30242	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ishoey M (2018)	29356495	228720	9765	Bivalent ligand 228	compound 8|Bivalent_ligand_228	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 8 (CRBN:phthalimide --- GSPT1:PHA665752)	-
30244	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ishoey M (2018)	29356495	228720	9829	Bivalent ligand 229	compound 27|Bivalent_ligand_229	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 27 (CRBN:phthalimide --- GSPT1:ponatinib)	-
30246	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Testa A (2020)	31746102	228721	9834	Bivalent ligand 230	macroPROTAC-1|Bivalent_ligand_230	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: macroPROTAC1 (VHL:VH032 ---BRD4:JQ1)	-
30248	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Shibata N (2018)	28594553	228722	9835	Bivalent ligand 231	SNIPER(AR)-51/compound 42a|Bivalent_ligand_231	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(AR)-51/compound 42a (BIRC2:bestatin --- AR:AR antagonist-1)	-
30250	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9813	Bivalent ligand 232	vhhGFP4-SPOP|Bivalent_ligand_232	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-SPOP (SPOP:vhhGFP4 --- H2B:GFP)	-
30252	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9819	Bivalent ligand 233	3G86.32|Bivalent_ligand_233	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: 3G86.32 (SPOP:3G86.32 --- H2B:GFP)	-
30254	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9830	Bivalent ligand 234	bGFP-A|Bivalent_ligand_234	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: bGFP-A (SPOP:bGFP-A --- H2B:GFP)	-
30256	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9810	Bivalent ligand 235	bGFP-C|Bivalent_ligand_235	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: bGFP-C (SPOP:bGFP-C --- H2B:GFP)	-
30258	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9828	Bivalent ligand 236	GS2|Bivalent_ligand_236	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: GS2 (SPOP:GS2 --- H2B:GFP)	-
30260	116887	23291	-	FBXW11	BTRC2|BTRCP2|FBW1B|FBXW1B|Fbw11|Hos	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9763	Bivalent ligand 237	vhhGFP4-BetaTrCP|Bivalent_ligand_237	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-TrCP (TrCP:vhhGFP4 --- H2B:GFP)	-
30262	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9811	Bivalent ligand 238	vhhGFP4-SKP2|Bivalent_ligand_238	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-SKP2 (SKP2:vhhGFP4 --- H2B:GFP)	-
30264	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9804	Bivalent ligand 239	vhhGFP4-FBW7|Bivalent_ligand_239	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-FBW7 (FBW7:vhhGFP4 --- H2B:GFP)	-
30266	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9775	Bivalent ligand 240	vhhGFP4-VHL|Bivalent_ligand_240	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-VHL (VHL:vhhGFP4 --- H2B:GFP)	-
30268	114362	8835	-	SOCS2	CIS2|Cish2|SOCS-2|SSI-2|SSI2|STATI2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9774	Bivalent ligand 241	vhhGFP4-SOCS2|Bivalent_ligand_241	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-SOCS2 (SOCS2:vhhGFP4 --- H2B:GFP)	-
30270	126610	140456	-	ASB11	-	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9773	Bivalent ligand 242	vhhGFP4-ASB1|Bivalent_ligand_242	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-ASB1 (ASB1:vhhGFP4 --- H2B:GFP)	-
30272	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9772	Bivalent ligand 243	vhhGFP4-CHIP|Bivalent_ligand_243	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-CHIP (CHIP:vhhGFP4 --- H2B:GFP)	-
30274	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9804	Bivalent ligand 239	vhhGFP4-FBW7|Bivalent_ligand_239	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-FBW7 (FBW7:vhhGFP4 --- PCNA:GFP)	-
30276	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9775	Bivalent ligand 240	vhhGFP4-VHL|Bivalent_ligand_240	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-VHL (VHL:vhhGFP4 --- PCNA:GFP)	-
30278	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9772	Bivalent ligand 243	vhhGFP4-CHIP|Bivalent_ligand_243	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-CHIP (CHIP:vhhGFP4 --- PCNA:GFP)	-
30280	114362	8835	-	SOCS2	CIS2|Cish2|SOCS-2|SSI-2|SSI2|STATI2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9774	Bivalent ligand 241	vhhGFP4-SOCS2|Bivalent_ligand_241	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-SOCS2 (SOCS2:vhhGFP4 --- PCNA:GFP)	-
30282	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9813	Bivalent ligand 232	vhhGFP4-SPOP|Bivalent_ligand_232	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-SPOP (SPOP:vhhGFP4 --- PCNA-GFP)	-
30284	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9819	Bivalent ligand 233	3G86.32|Bivalent_ligand_233	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: 3G86.32 (SPOP:3G86.32 --- PCNA:GFP)	-
30286	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9830	Bivalent ligand 234	bGFP-A|Bivalent_ligand_234	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: bGFP-A (SPOP:bGFP-A  --- PCNA:GFP)	-
30288	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9810	Bivalent ligand 235	bGFP-C|Bivalent_ligand_235	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: bGFP-C (SPOP:bGFP-C  --- PCNA:GFP)	-
30290	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9828	Bivalent ligand 236	GS2|Bivalent_ligand_236	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: GS2 (SPOP:GS2 --- PCNA:GFP)	-
30292	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2019)	31804827	227993	9779	Bivalent ligand 244	ARD-266|Bivalent_ligand_244	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-266 (VHL:VHL-g --- AR:ARi-16)	-
30294	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Vannam R (2021)	33400925	228723	9778	Bivalent ligand 245	dCBP-1|Bivalent_ligand_245	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	target	Standardized BVL Name: dCBP-1 (CRBN:lenalidomide --- EP300:GNE-781)	-
30296	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Vannam R (2021)	33400925	228723	9778	Bivalent ligand 245	dCBP-1|Bivalent_ligand_245	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	target	Standardized BVL Name: dCBP-1 (CRBN:lenalidomide --- CREBBP:GNE-781)	-
30298	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li Y (2019)	30525597	223612	9809	Bivalent ligand 246	MD-222|Bivalent_ligand_246	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: MD-222 (CRBN:lenalidomide --- MDM2:MI-1061)	-
30300	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2018)	30067223	228458	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121420	57167	-	SALL4	DRRS|HSAL4|ZNF797|dJ1112F19.1	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:thalidomide --- SALL4:thalidomide)	-
30302	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2018)	30067223	228458	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121420	57167	-	SALL4	DRRS|HSAL4|ZNF797|dJ1112F19.1	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:pomalidomide --- SALL4:pomalidomide)	-
30304	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2018)	30067223	228458	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121420	57167	-	SALL4	DRRS|HSAL4|ZNF797|dJ1112F19.1	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:lenalidomide --- SALL4:lenalidomide)	-
30306	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Petzold G (2016)	26909574	193065	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:lenalidomide --- CSNK1A1:lenalidomide)	-
30308	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Lv L (2020)	32804079	223704	9760	Bivalent ligand 247	HQ461|Bivalent_ligand_247	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: HQ461 (DDB1:HQ461 --- CDK12 + CCNK:HQ461)	-
30310	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Slabicki M (2020)	32494016	228456	9807	Bivalent ligand 248	R-CR8|Bivalent_ligand_248	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: R-CR8 (DDB1:CR8 --- CDK12 + CCNK:CR8)	-
30312	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9764	Bivalent ligand 249	dCeMM1|Bivalent_ligand_249	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM1 (DDB1:dCeMM1 --- CDK12 + CCNK:dCeMM1)	-
30314	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9812	Bivalent ligand 250	dCeMM2|Bivalent_ligand_250	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM2 (DDB1:dCeMM2 --- CDK12 + CCNK:dCeMM2)	-
30316	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9759	Bivalent ligand 251	dCeMM3|Bivalent_ligand_251	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM3 (DDB1:dCeMM3 --- CDK12 + CCNK:dCeMM3)	-
30318	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9814	Bivalent ligand 252	dCeMM4|Bivalent_ligand_252	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM4 (DDB1:dCeMM4 --- CDK12 + CCNK:dCeMM4)	-
30320	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Alabi S (2021)	33568647	228724	9815	Bivalent ligand 253	SJF-0628|Bivalent_ligand_253	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: SJF-0628 (VHL:HIF-1alpha hydroxyproline derived small molecule --- BRAF V600E mutant:vemurafenib)	-
30322	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Tochigi T (2020)	32219443	226662	9816	Bivalent ligand 254	Bivalent_ligand_254	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107960	1588	-	CYP19A1	ARO|ARO1|CPV1|CYAR|CYP19|CYPXIX|P-450AROM	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:lenalidomide --- CYP19A1:lenalidomide)	-
30324	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu H (2019)	31271281	228479	9817	Bivalent ligand 255	Bivalent_ligand_255	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: (CRBN:pomalidomide  ---HDAC6:Nexturastat A)	-
30326	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- YES1:foretinib)	-
30328	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108379	2067	-	ERCC1	COFS4|RAD10|UV20	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ERCC1:foretinib)	-
30330	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122928	79837	-	PIP4K2C	PIP5K2C	9606	Homo sapiens	target	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand ---PIP4K2C:foretinib)	-
30332	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112401	6510	-	SLC1A5	AAAT|ASCT2|ATBO|M7V1|M7VS1|R16|RDRC	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC1A5-FKBP12F36V:AP1867)	-
30334	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112406	6515	-	SLC2A3	GLUT3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC2A3-FKBP12F36V:AP1867)	-
30336	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123509	81539	-	SLC38A1	ATA1|NAT2|SAT1|SNAT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC38A1-FKBP12F36V:AP1867)	-
30338	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112404	6513	-	SLC2A1	DYT17|DYT18|DYT9|EIG12|GLUT|GLUT-1|GLUT1|GLUT1DS|HTLVR|PED	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC2A1-FKBP12F36V:AP1867)	-
30340	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112438	6548	RP4-633N17.1	SLC9A1	APNH|NHE-1|NHE1|PPP1R143	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC9A15-FKBP12F36V:AP1867)	-
30342	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112454	6566	RP4-580L15.1	SLC16A1	HHF7|MCT|MCT1|MCT1D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC16A1-FKBP12F36V:AP1867)	-
30344	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113652	7922	DADB-100D22.3	SLC39A7	D6S115E|D6S2244E|H2-KE4|HKE4|KE4|RING5|ZIP7	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC39A7-FKBP12F36V:AP1867)	-
30346	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115726	10463	-	SLC30A9	C4orf1|GAC63|HUEL|ZNT9	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC30A9-FKBP12F36V:AP1867)	-
30348	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	131484	347734	RP1-302G2.3	SLC35B2	PAPST1|SLL|UGTrel4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC35B2-FKBP12F36V:AP1867)	-
30350	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114632	9197	-	SLC33A1	ACATN|AT-1|AT1|CCHLND|SPG42	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC33A1-FKBP12F36V:AP1867)	-
30352	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127480	153129	-	SLC38A9	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC38A9-FKBP12F36V:AP1867)	-
30354	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119943	54407	-	SLC38A2	ATA2|PRO1068|SAT2|SNAT2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC38A2-FKBP12F36V:AP1867)	-
30356	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8522	Bivalent ligand 132	d9A-2|Bivalent_ligand_132	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112438	6548	RP4-633N17.1	SLC9A1	APNH|NHE-1|NHE1|PPP1R143	9606	Homo sapiens	target	Standardized BVL Name: d9A2 (CRBN:phthalimide --- SLC9A1:W9A)	-
30358	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8522	Bivalent ligand 132	d9A-2|Bivalent_ligand_132	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112439	6549	-	SLC9A2	NHE2	9606	Homo sapiens	target	Standardized BVL Name: d9A2 (CRBN:phthalimide --- SLC9A2:W9A)	-
30360	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8522	Bivalent ligand 132	d9A-2|Bivalent_ligand_132	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	132934	389015	-	SLC9A4	NHE4	9606	Homo sapiens	target	Standardized BVL Name: d9A2 (CRBN:phthalimide --- SLC9A4:W9A)	-
30362	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8522	Bivalent ligand 132	d9A-2|Bivalent_ligand_132	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124198	84679	-	SLC9A7	NHE-7|NHE7|SLC9A6	9606	Homo sapiens	target	Standardized BVL Name: d9A2 (CRBN:phthalimide --- SLC9A7:W9A)	-
30364	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bensimon A (2020)	32386596	223637	8522	Bivalent ligand 132	d9A-2|Bivalent_ligand_132	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127264	150159	-	SLC9B1	NHA1|NHEDC1	9606	Homo sapiens	target	Standardized BVL Name: d9A2 (CRBN:phthalimide --- SLC9B1:W9A)	-
30366	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jin YH (2020)	32153174	223638	8521	Bivalent ligand 133	Azo-PROTAC-4C|Bivalent_ligand_133	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: Azo-PROTAC-4C (CRBN:lenalidomide --- BCR-ABL:dasatinib)	-
30368	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xue G (2019)	31566962	223639	8524	Bivalent ligand 134	pc-PROTAC1|Bivalent_ligand_134	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: pc-PROTAC1 (CRBN:thalidomide --- BCR4:JQ1)	-
30370	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xue G (2019)	31566962	223639	8523	Bivalent ligand 135	pc-PROTAC3|Bivalent_ligand_135	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: pc-PROTAC3 (CRBN:thalidomide --- BTK:MT-802)	-
30372	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Pairawan S (2021)	33663585	228644	9937	ALRN-6924	CS-0044703	-	PUBCHEM	381833444	-	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	-
30373	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Pairawan S (2021)	33663585	228644	9937	ALRN-6924	CS-0044703	-	PUBCHEM	381833444	-	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	-
30374	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Lin HC (2021)	33582217	231961	812	Disulfiram	Tetraethylthiuram Disulfide|Tetraethylthioperoxydicarbonic Diamide|Tetraethylthiuram Disulphide|1,1'-dithiobis(N,N-diethylthioformamide)|N,N,N',N'-tetraethylthiuram disulfide|Antabuse (tn)|Disulfiram|Bis(diethylthiocarbamoyl) disulfide	antabuse tab 0.25gm|antabuse t	DRUGBANK	DB00822	C10H20N2S4	small molecule	P03AA54|P03AA04|N07BB01	97-77-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUZONCFQVSMFAP-UHFFFAOYSA-N
30375	117950	27005	RP11-297K8.3	USP21	USP16|USP23	9606	Homo sapiens	inhibitor	target	Lin HC (2021)	33582217	231961	812	Disulfiram	Tetraethylthiuram Disulfide|Tetraethylthioperoxydicarbonic Diamide|Tetraethylthiuram Disulphide|1,1'-dithiobis(N,N-diethylthioformamide)|N,N,N',N'-tetraethylthiuram disulfide|Antabuse (tn)|Disulfiram|Bis(diethylthiocarbamoyl) disulfide	antabuse tab 0.25gm|antabuse t	DRUGBANK	DB00822	C10H20N2S4	small molecule	P03AA54|P03AA04|N07BB01	97-77-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUZONCFQVSMFAP-UHFFFAOYSA-N
30376	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Lin HC (2021)	33582217	231961	344	Tioguanine	2-Amino-6-mercaptopurine|2-Amino-6-purinethiol|Tioguanin|2-aminopurine-6-thiol|6-TG|Tioguanine|2-amino-1,9-Dihydropurine-6-thione|2-Amino-1,7-dihydro-6H-purine-6-thione|6-Thioguanine|Thioguanine|2-Aminopurin-6-thiol|6-Mercaptoguanine|2-Amino 6mp|2-amino-1H-purine-6(7H)-thione|Tioguanina|ThG|TG|Tioguaninum|2-Amino-6-merkaptopurin|2-Aminopurine-6(1H)-thione|6-Mercapto-2-aminopurine|6-thioguanine	tabloid|lanvis	DRUGBANK	DB00352	C5H5N5S	small molecule	L01BB03	154-42-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WYWHKKSPHMUBEB-UHFFFAOYSA-N
30377	117950	27005	RP11-297K8.3	USP21	USP16|USP23	9606	Homo sapiens	inhibitor	target	Lin HC (2021)	33582217	231961	344	Tioguanine	2-Amino-6-mercaptopurine|2-Amino-6-purinethiol|Tioguanin|2-aminopurine-6-thiol|6-TG|Tioguanine|2-amino-1,9-Dihydropurine-6-thione|2-Amino-1,7-dihydro-6H-purine-6-thione|6-Thioguanine|Thioguanine|2-Aminopurin-6-thiol|6-Mercaptoguanine|2-Amino 6mp|2-amino-1H-purine-6(7H)-thione|Tioguanina|ThG|TG|Tioguaninum|2-Amino-6-merkaptopurin|2-Aminopurine-6(1H)-thione|6-Mercapto-2-aminopurine|6-thioguanine	tabloid|lanvis	DRUGBANK	DB00352	C5H5N5S	small molecule	L01BB03	154-42-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WYWHKKSPHMUBEB-UHFFFAOYSA-N
30378	116183	10987	-	COPS5	CSN5|JAB1|MOV-34|SGN5	9606	Homo sapiens	inhibitor	target	Liu Y (2020)	33354502	229845	3947	Berberine	-	-	DRUGBANK	DB04115	C20H18NO4	small molecule	-	2086-83-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YBHILYKTIRIUTE-UHFFFAOYSA-N
30379	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Li X (2020)	32029476	227136	9970	Parthenolide	Parthenolide|(1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one|Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-|(-)-Parthenolide|(1aR,4E,7aS,10aS,10bR)-1a,5-Dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one	-	CHEMSPIDER	4976071	C15H20O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KTEXNACQROZXEV-PVLRGYAZSA-N
30380	114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 70	MZBFFXLYQTWKNV-INIZCTEOSA-N
30381	113221	7375	-	USP4	UNP|Unph	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 34	MZBFFXLYQTWKNV-INIZCTEOSA-N
30382	113751	8078	-	USP5	ISOT	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 72	MZBFFXLYQTWKNV-INIZCTEOSA-N
30383	114552	9098	-	USP6	HRP1|TRE17|TRE2|TRESMCR|Tre-2|USP6-short	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 22	MZBFFXLYQTWKNV-INIZCTEOSA-N
30384	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 28	MZBFFXLYQTWKNV-INIZCTEOSA-N
30385	114555	9101	-	USP8	HumORF8|SPG59|UBPY	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 74	MZBFFXLYQTWKNV-INIZCTEOSA-N
30386	114554	9100	-	USP10	UBPO	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 74	MZBFFXLYQTWKNV-INIZCTEOSA-N
30387	113866	8237	RP4-659F15.2	USP11	UHX1	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 73	MZBFFXLYQTWKNV-INIZCTEOSA-N
30388	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 30	MZBFFXLYQTWKNV-INIZCTEOSA-N
30389	115848	10600	MSTP039	USP16	UBP-M|UBPM	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 32	MZBFFXLYQTWKNV-INIZCTEOSA-N
30390	132019	377630	-	USP17L2	DUB-3|DUB3|USP17	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 26	MZBFFXLYQTWKNV-INIZCTEOSA-N
30391	116077	10868	-	USP20	LSFR3A|VDU2|hVDU2	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 39	MZBFFXLYQTWKNV-INIZCTEOSA-N
30392	116939	23358	hCG_33036	USP24	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 100	MZBFFXLYQTWKNV-INIZCTEOSA-N
30393	123764	83844	RP1-97K10.1	USP26	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 26	MZBFFXLYQTWKNV-INIZCTEOSA-N
30394	133302	389856	-	USP27X	USP22L|USP27	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 60	MZBFFXLYQTWKNV-INIZCTEOSA-N
30395	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 41	MZBFFXLYQTWKNV-INIZCTEOSA-N
30396	121696	57663	-	USP29	HOM-TES-84/86	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 37	MZBFFXLYQTWKNV-INIZCTEOSA-N
30397	121548	57478	RP11-20G6.3	USP31	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 16	MZBFFXLYQTWKNV-INIZCTEOSA-N
30398	124189	84669	-	USP32	NY-REN-60|USP10	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 45	MZBFFXLYQTWKNV-INIZCTEOSA-N
30399	116671	23032	-	USP33	VDU1	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 95	MZBFFXLYQTWKNV-INIZCTEOSA-N
30400	121613	57558	-	USP35	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 86	MZBFFXLYQTWKNV-INIZCTEOSA-N
30401	121651	57602	-	USP36	DUB1	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 71	MZBFFXLYQTWKNV-INIZCTEOSA-N
30402	121720	57695	-	USP37	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 31	MZBFFXLYQTWKNV-INIZCTEOSA-N
30403	124165	84640	-	USP38	HP43.8KD	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 40	MZBFFXLYQTWKNV-INIZCTEOSA-N
30404	123904	84132	tcag7.880	USP42	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 47	MZBFFXLYQTWKNV-INIZCTEOSA-N
30405	124430	85015	RP11-98I9.5	USP45	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 31	MZBFFXLYQTWKNV-INIZCTEOSA-N
30406	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 33	MZBFFXLYQTWKNV-INIZCTEOSA-N
30407	107920	1540	HSPC057	CYLD	BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 61	MZBFFXLYQTWKNV-INIZCTEOSA-N
30501	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10155	Bivalent ligand 257	POM-PERM3-R7|Bivalent_ligand_257	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: POM-PERM3-R7 (CRBN:pomalidomide ---AR:PERM3-R7)	-
30503	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10155	Bivalent ligand 257	POM-PERM3-R7|Bivalent_ligand_257	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: POM-PERM3-R7 (CRBN:pomalidomide ---ESR1:PERM3-R7)	-
30505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10144	Bivalent ligand 258	VH032-PERM3-R7|Bivalent_ligand_258	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: VH032-PERM3-R7 (VHL:VH032 ---AR:PERM3-R7)	-
30507	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10144	Bivalent ligand 258	VH032-PERM3-R7|Bivalent_ligand_258	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: VH032-PERM3-R7 (VHL:VH032 ---ESR1:PERM3-R7)	-
30509	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (XIAP:MV1 ---AR:PERM3-R7)	-
30511	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (XIAP:MV1 ---ESR1:PERM3-R7)	-
30513	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (BIRC2:MV1 ---AR:PERM3-R7)	-
30515	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (BIRC2:MV1 ---ESR1:PERM3-R7)	-
30517	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (XIAP:LCL161 ---AR:PERM3-R7)	-
30519	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (XIAP:LCL161 ---AR:PERM3-R7)	-
30521	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (BIRC2:LCL161 ---ESR1:PERM3-R7)	-
30523	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (BIRC2:LCL161 ---ESR1:PERM3-R7)	-
30531	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide---AAK1:TAE684)	-
30533	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ABL1:TAE684)	-
30535	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ABL2:TAE684)	-
30537	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- AKT2:TAE684)	-
30539	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- AKT3:TAE684)	-
30541	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- AURKA:TAE684)	-
30543	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- AURKB:TAE684)	-
30545	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BCKDK:TAE684)	-
30547	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BLK:TAE684)	-
30549	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BMP2K:TAE684)	-
30551	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107125	657	-	BMPR1A	10q23del|ACVRLK3|ALK3|CD292|SKR5	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BMPR1A:TAE684)	-
30553	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BUB1:TAE684)	-
30555	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- BUB1B:TAE684)	-
30557	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113914	8317	-	CDC7	CDC7L1|HsCDC7|Hsk1|huCDC7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDC7:TAE684)	-
30559	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK10:TAE684)	-
30561	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK12:TAE684)	-
30563	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK13:TAE684)	-
30565	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK14:TAE684)	-
30567	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK16:TAE684)	-
30569	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK17:TAE684)	-
30571	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111156	5129	RP11-288G13.1	CDK18	PCTAIRE|PCTAIRE3|PCTK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK18:TAE684)	-
30573	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK2:TAE684)	-
30575	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK4:TAE684)	-
30577	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK5:TAE684)	-
30579	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK6:TAE684)	-
30581	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK7:TAE684)	-
30583	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK9:TAE684)	-
30585	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CSK:TAE684)	-
30587	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CSNK1D:TAE684)	-
30589	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- EPHB2:TAE684)	-
30591	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108364	2050	-	EPHB4	HTK|MYK1|TYRO11	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- EPHB4:TAE684)	-
30593	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- FER:TAE684)	-
30595	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- FYN:TAE684)	-
30597	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- GAK:TAE684)	-
30599	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	128490	204851	RP4-786G8.2	HIPK1	Myak|Nbak2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- HIPK1:TAE684)	-
30601	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ITK:TAE684)	-
30603	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LATS1:TAE684)	-
30605	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LCK:TAE684)	-
30607	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LIMK1:TAE684)	-
30609	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LIMK2:TAE684)	-
30611	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LRRK2:TAE684)	-
30613	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP3K1:TAE684)	-
30615	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP3K11:TAE684)	-
30617	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113566	7786	-	MAP3K12	DLK|MEKK12|MUK|ZPK|ZPKP1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP3K12:TAE684)	-
30619	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124089	84451	RP5-862P8.2	KIAA1804	MLK4|dJ862P8.3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP3K21:TAE684)	-
30621	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP4K1:TAE684)	-
30623	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAP4K3:TAE684)	-
30625	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAPK6:TAE684)	-
30627	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30629	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MARK2:TAE684)	-
30631	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MARK4:TAE684)	-
30633	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116670	23031	-	MAST3	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAST3:TAE684)	-
30635	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MKNK2:TAE684)	-
30637	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110826	4751	-	NEK2	HsPK21|NEK2A|NLK1|PPP1R111|RP67	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- NEK2:TAE684)	-
30639	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PDK3:TAE684)	-
30641	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PLK1:TAE684)	-
30643	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PLK4:TAE684)	-
30645	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127591	157285	-	SGK223	PRAGMIN	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PRAG1:TAE684)	-
30647	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PRKAA1:TAE684)	-
30649	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PRKAA2:TAE684)	-
30651	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PTK2:TAE684)	-
30653	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PTK2B:TAE684)	-
30655	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111720	5753	-	PTK6	BRK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PTK6:TAE684)	-
30657	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120896	55781	-	RIOK2	RIO2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RIOK2:TAE684)	-
30659	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KA1:TAE684)	-
30661	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118144	27330	-	RPS6KA6	PP90RSK4|RSK4	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KA6:TAE684)	-
30663	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KB1:TAE684)	-
30665	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117810	26750	-	RPS6KC1	RPK118|RSKL1|S6K-delta-1|S6PKh1|humS6PKh1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KC1:TAE684)	-
30667	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	132609	388228	-	SBK1	SBK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- SBK1:TAE684)	-
30669	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- SIK2:TAE684)	-
30671	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- SRC:TAE684)	-
30673	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- STK17A:TAE684)	-
30675	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- STK17B:TAE684)	-
30677	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	129429	282974	RP11-140A10.1	STK32C	PKE|YANK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- STK32C:TAE684)	-
30679	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- STK33:TAE684)	-
30681	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123816	83931	-	STK40	SHIK|SgK495	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- STK40:TAE684)	-
30683	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TEC:TAE684)	-
30685	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TGFBR1:TAE684)	-
30687	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114253	8711	-	TNK1	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TNK1:TAE684)	-
30689	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TNK2:TAE684)	-
30691	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121756	57761	RP5-1103G7.7	TRIB3	C20orf97|NIPK|SINK|SKIP3|TRB3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TRIB3:TAE684)	-
30693	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120177	54822	-	TRPM7	ALSPDC|CHAK|CHAK1|LTRPC7|LTrpC-7|TRP-PLIK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TRPM7:TAE684)	-
30695	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TTK:TAE684)	-
30697	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- UHMK1:TAE684)	-
30699	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ULK1:TAE684)	-
30701	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117470	25989	-	ULK3	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ULK3:TAE684)	-
30703	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- WEE1:TAE684)	-
30705	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- YES1:TAE684)	-
30707	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10009	Bivalent Ligand 265	dAURK-4|Bivalent_Ligand_265	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAURK-4 (CRBN:thalidomide---AURKA:Alisertib)	-
30709	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10009	Bivalent Ligand 265	dAURK-4|Bivalent_Ligand_265	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: dAURK-4 (CRBN:thalidomide--- AURKB:Alisertib)	-
30711	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10012	Bivalent Ligand 266	FMF-05-178-1|Bivalent_Ligand_266	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: FMF-05-178-1 (VHL:VHL-1---BLK:XMD)	-
30713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10012	Bivalent Ligand 266	FMF-05-178-1|Bivalent_Ligand_266	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-05-178-1 (VHL:VHL-1--- CSK:XMD)	-
30715	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide---AAK1:TAE684)	-
30717	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- ABL1:TAE684)	-
30719	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- AURKA:TAE684)	-
30721	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- AURKB:TAE684)	-
30723	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- BLK:TAE684)	-
30725	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107125	657	-	BMPR1A	10q23del|ACVRLK3|ALK3|CD292|SKR5	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- BMPR1A:TAE684)	-
30727	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- BUB1:TAE684)	-
30729	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- BUB1B:TAE684)	-
30731	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK10:TAE684)	-
30733	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK12:TAE684)	-
30735	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK13:TAE684)	-
30737	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK17:TAE684)	-
30739	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK2:TAE684)	-
30741	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK4:TAE684)	-
30743	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK5:TAE684)	-
30745	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK6:TAE684)	-
30747	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK7:TAE684)	-
30749	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK9:TAE684)	-
30751	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- COQ8A:TAE684)	-
30753	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123009	79934	-	ADCK4	NPHS9	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- COQ8B:TAE684)	-
30755	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CSNK1D:TAE684)	-
30757	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107838	1454	RP1-5O6.1	CSNK1E	CKIepsilon|HCKIE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CSNK1E:TAE684)	-
30759	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118953	29904	-	EEF2K	HSU93850|eEF-2K	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- EEF2K:TAE684)	-
30761	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- FER:TAE684)	-
30763	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108609	2321	-	FLT1	FLT|FLT-1|VEGFR-1|VEGFR1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- FLT1:TAE684)	-
30765	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- GAK:TAE684)	-
30767	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123814	83903	-	GSG2	HASPIN	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- HASPIN:TAE684)	-
30769	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- IRAK4:TAE684)	-
30771	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- ITK:TAE684)	-
30773	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- LCK:TAE684)	-
30775	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- LIMK1:TAE684)	-
30777	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- LIMK2:TAE684)	-
30779	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAP3K11:TAE684)	-
30781	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124089	84451	RP5-862P8.2	KIAA1804	MLK4|dJ862P8.3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAP3K21:TAE684)	-
30783	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAP4K1:TAE684)	-
30785	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAP4K3:TAE684)	-
30787	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAPK6:TAE684)	-
30789	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30791	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MARK2:TAE684)	-
30793	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MARK4:TAE684)	-
30795	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110826	4751	-	NEK2	HsPK21|NEK2A|NLK1|PPP1R111|RP67	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- NEK2:TAE684)	-
30797	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- NLK:TAE684)	-
30799	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PDK2:TAE684)	-
30801	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PLK4:TAE684)	-
30803	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127591	157285	-	SGK223	PRAGMIN	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PRAG1:TAE684)	-
30805	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PRKAA1:TAE684)	-
30807	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PTK2B:TAE684)	-
30809	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120896	55781	-	RIOK2	RIO2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- RIOK2:TAE684)	-
30811	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- RPS6KA1:TAE684)	-
30813	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- SIK2:TAE684)	-
30815	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- SRC:TAE684)	-
30817	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- STK10:TAE684)	-
30819	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- STK17A:TAE684)	-
30821	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- STK35:TAE684)	-
30823	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- TEC:TAE684)	-
30825	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- TNK2:TAE684)	-
30827	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- ULK1:TAE684)	-
30829	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117470	25989	-	ULK3	-	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- ULK3:TAE684)	-
30831	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- WEE1:TAE684)	-
30833	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- YES1:TAE684)	-
30835	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide---ABL2:GNF-7)	-
30837	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- AURKA:GNF-7)	-
30839	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- BLK:GNF-7)	-
30841	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- BUB1:GNF-7)	-
30843	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	609064	728642	RP1-283E3.2	CDK11A	CDC2L2|CDC2L3|CDK11-p110|CDK11-p46|CDK11-p58|PITSLRE|p58GTA	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CDK11A:GNF-7)	-
30845	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CDK11B:GNF-7)	-
30847	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CDK4:GNF-7)	-
30849	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CSK:GNF-7)	-
30851	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110975	4921	RP11-572K18.1	DDR2	MIG20a|NTRKR3|TKT|TYRO10	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- DDR2:GNF-7)	-
30853	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- EPHA3:GNF-7)	-
30855	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108363	2049	-	EPHB3	ETK2|HEK2|TYRO6	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- EPHB3:GNF-7)	-
30857	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108365	2051	-	EPHB6	HEP	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- EPHB6:GNF-7)	-
30859	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- FER:GNF-7)	-
30861	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- FYN:GNF-7)	-
30863	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- GAK:GNF-7)	-
30865	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LATS1:GNF-7)	-
30867	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LCK:GNF-7)	-
30869	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LIMK1:GNF-7)	-
30871	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LIMK2:GNF-7)	-
30873	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LRRK2:GNF-7)	-
30875	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110245	4067	-	LYN	JTK8|p53Lyn|p56Lyn	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LYN:GNF-7)	-
30877	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP3K1:GNF-7)	-
30879	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP3K11:GNF-7)	-
30881	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP3K20:GNF-7)	-
30883	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP4K1:GNF-7)	-
30885	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP4K2:GNF-7)	-
30887	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAP4K5:GNF-7)	-
30889	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111586	5600	-	MAPK11	P38B|P38BETA2|PRKM11|SAPK2|SAPK2B|p38-2|p38Beta	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK11:GNF-7)	-
30891	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112207	6300	-	MAPK12	ERK-6|ERK3|ERK6|MAPK 12|P38GAMMA|PRKM12|SAPK-3|SAPK3	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK12:GNF-7)	-
30893	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
30895	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
30897	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
30899	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPKAPK2:GNF-7)	-
30901	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MKNK2:GNF-7)	-
30903	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- NLK:GNF-7)	-
30905	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- PLK1:GNF-7)	-
30907	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- PTK2:GNF-7)	-
30909	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- PTK2B:GNF-7)	-
30911	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- RIPK1:GNF-7)	-
30913	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- RIPK2:GNF-7)	-
30915	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- RPS6KA3:GNF-7)	-
30917	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- SIK2:GNF-7)	-
30919	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- SRC:GNF-7)	-
30921	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114750	9344	UNQ2971/PRO7431	TAOK2	MAP3K17|PSK|PSK1|PSK1-BETA|TAO1|TAO2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide---TAOK2:GNF-7)	-
30923	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- TEC:GNF-7)	-
30925	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- TNK2:GNF-7)	-
30927	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- TTK:GNF-7)	-
30929	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- UHMK1:GNF-7)	-
30931	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- ULK1:GNF-7)	-
30933	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- WEE1:GNF-7)	-
30935	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- YES1:GNF-7)	-
30937	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1---AAK1:TAE)	-
30939	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ABL2:TAE)	-
30941	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- AURKA:TAE)	-
30943	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- AURKB:TAE)	-
30945	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- BUB1B:TAE)	-
30947	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113914	8317	-	CDC7	CDC7L1|HsCDC7|Hsk1|huCDC7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDC7:TAE)	-
30949	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK1:TAE)	-
30951	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK12:TAE)	-
30953	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK13:TAE)	-
30955	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK2:TAE)	-
30957	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK4:TAE)	-
30959	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDk6:TAE)	-
30961	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK7:TAE)	-
30963	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK9:TAE)	-
30965	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CHEK1:TAE)	-
30967	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CSNK1D:TAE)	-
30969	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108355	2041	-	EPHA1	EPH|EPHT|EPHT1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- EPHA1:TAE)	-
30971	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- FER:TAE)	-
30973	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108551	2260	-	FGFR1	BFGFR|CD331|CEK|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- FGFR1:TAE)	-
30975	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- GAK:TAE)	-
30977	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- IRAK4:TAE)	-
30979	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ITK:TAE)	-
30981	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- LIMK2:TAE)	-
30983	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAP4K2:TAE)	-
30985	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAP4K3:TAE)	-
30987	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAPK6:TAE)	-
30989	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAPK7:TAE)	-
30991	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MARK4:TAE)	-
30993	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115171	9833	RP11-8N6.1	MELK	HPK38	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MELK:TAE)	-
30995	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118978	29941	RP11-545E17.1	PKN3	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PKN3:TAE)	-
30997	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PLK4:TAE)	-
30999	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PRKAA1:TAE)	-
31001	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PTK2:TAE)	-
31003	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111720	5753	-	PTK6	BRK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PTK6:TAE)	-
31005	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114468	8986	-	RPS6KA4	MSK2|RSK-B	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- RPS6KA4:TAE)	-
31007	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- SIK2:TAE)	-
31009	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- STK35:TAE)	-
31011	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- TNK2:TAE)	-
31013	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- UHMK1:TAE)	-
31015	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ULK1:TAE)	-
31017	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- WEE1:TAE)	-
31019	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide---AAK1:Ceritinib)	-
31021	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- AURKA:Ceritinib)	-
31023	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- AURKB:Ceritinib)	-
31025	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31027	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK12:Ceritinib)	-
31029	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK16:Ceritinib)	-
31031	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK17:Ceritinib)	-
31033	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31035	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK5:Ceritinib)	-
31037	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK7:Ceritinib)	-
31039	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK9:Ceritinib)	-
31041	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CLK1:Ceritinib)	-
31043	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- FER:Ceritinib)	-
31045	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- GSK3A:Ceritinib)	-
31047	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- GSK3B:Ceritinib)	-
31049	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116382	11213	-	IRAK3	ASRT5|IRAKM	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- IRAK3:Ceritinib)	-
31051	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAP3K11:Ceritinib)	-
31053	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31055	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31057	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110825	4750	-	NEK1	NY-REN-55|SRPS2|SRPS2A|SRTD6	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NEK1:Ceritinib)	-
31059	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110827	4752	RP11-248G5.5	NEK3	HSPK36	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NEK3:Ceritinib)	-
31061	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112663	6787	-	NEK4	NRK2|STK2|pp12301	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NEK4:Ceritinib)	-
31063	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NEK9:Ceritinib)	-
31065	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NUAK1:Ceritinib)	-
31067	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PRKAA1:Ceritinib)	-
31069	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PRKAA2:Ceritinib)	-
31071	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PTK2:Ceritinib)	-
31073	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PTK2B:Ceritinib)	-
31075	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
31077	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
31079	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114468	8986	-	RPS6KA4	MSK2|RSK-B	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- RPS6KA4:Ceritinib)	-
31081	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- STK33:Ceritinib)	-
31083	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- STK35:Ceritinib)	-
31085	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- STK38:Ceritinib)	-
31087	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- TBK1:Ceritinib)	-
31089	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- TEC:Ceritinib)	-
31091	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- TTK:Ceritinib)	-
31093	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- WEE1:Ceritinib)	-
31095	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide---ABL1:GNF-7)	-
31097	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- ABL2:GNF-7)	-
31099	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- BLK:GNF-7)	-
31101	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- BUB1:GNF-7)	-
31103	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- CDK11B:GNF-7)	-
31105	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- CDK4:GNF-7)	-
31107	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- CSK:GNF-7)	-
31109	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108365	2051	-	EPHB6	HEP	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- EPHB6:GNF-7)	-
31111	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- FER:GNF-7)	-
31113	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- FYN:GNF-7)	-
31115	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- GAK:GNF-7)	-
31117	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- LCK:GNF-7)	-
31119	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- LIMK1:GNF-7)	-
31121	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAP3K1:GNF-7)	-
31123	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAP3K11:GNF-7)	-
31125	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAP3K20:GNF-7)	-
31127	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAP4K1:GNF-7)	-
31129	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK14:GNF-7)	-
31131	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK8:GNF-7)	-
31133	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK9:GNF-7)	-
31135	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPKAPK2:GNF-7)	-
31137	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MKNK2:GNF-7)	-
31139	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115586	10298	-	PAK4	-	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- PAK4:GNF-7)	-
31141	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127209	149420	RP11-96L14.4	PDIK1L	CLIK1L|STK35L2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- PDIK1L:GNF-7)	-
31143	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- PTK2B:GNF-7)	-
31145	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- RPS6KA1:GNF-7)	-
31147	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- RPS6KA3:GNF-7)	-
31149	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- SIK2:GNF-7)	-
31151	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- SRC:GNF-7)	-
31153	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- TNK2:GNF-7)	-
31155	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- UHMK1:GNF-7)	-
31157	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide--- ULK1:GNF-7)	-
31159	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: DB0662 (CRBN:thalidomide---YES1:GNF-7)	-
31161	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide---AAK1:Rebastinib)	-
31163	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- ABL2:Rebastinib)	-
31165	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- AURKA:Rebastinib)	-
31167	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- AURKB:Rebastinib)	-
31169	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- BLK:Rebastinib)	-
31171	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- BUB1B:Rebastinib)	-
31173	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK13:Rebastinib)	-
31175	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK17:Rebastinib)	-
31177	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK2:Rebastinib)	-
31179	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK4:Rebastinib)	-
31181	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK5:Rebastinib)	-
31183	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK6:Rebastinib)	-
31185	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK7:Rebastinib)	-
31187	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK9:Rebastinib)	-
31189	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- FER:Rebastinib)	-
31191	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- ITK:Rebastinib)	-
31193	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- LCK:Rebastinib)	-
31195	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- LIMK1:Rebastinib)	-
31197	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- LIMK2:Rebastinib)	-
31199	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- MAP3K11:Rebastinib)	-
31201	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- MARK4:Rebastinib)	-
31203	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- PLK4:Rebastinib)	-
31205	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- PRKAA1:Rebastinib)	-
31207	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- RPS6KA1:Rebastinib)	-
31209	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- SRC:Rebastinib)	-
31211	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- STK10:Rebastinib)	-
31213	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- STK38:Rebastinib)	-
31215	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- TEC:Rebastinib)	-
31217	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- TNK2:Rebastinib)	-
31219	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- ULK1:Rebastinib)	-
31221	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117470	25989	-	ULK3	-	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- ULK3:Rebastinib)	-
31223	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- WEE1:Rebastinib)	-
31225	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide---ABL1:Ponatinib)	-
31227	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- ABL2:Ponatinib)	-
31229	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- BLK:Ponatinib)	-
31231	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK14:Ponatinib)	-
31233	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK17:Ponatinib)	-
31235	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK5:Ponatinib)	-
31237	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK6:Ponatinib)	-
31239	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- COQ8A:Ponatinib)	-
31241	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108355	2041	-	EPHA1	EPH|EPHT|EPHT1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- EPHA1:Ponatinib)	-
31243	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108288	1969	-	EPHA2	ARCC2|CTPA|CTPP1|CTRCT6|ECK	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- EPHA2:Ponatinib)	-
31245	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- FER:Ponatinib)	-
31247	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- FYN:Ponatinib)	-
31249	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- GAK:Ponatinib)	-
31251	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109863	3654	-	IRAK1	IRAK|pelle	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- IRAK1:Ponatinib)	-
31253	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- LCK:Ponatinib)	-
31255	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110245	4067	-	LYN	JTK8|p53Lyn|p56Lyn	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- LYN:Ponatinib)	-
31257	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAP3K1:Ponatinib)	-
31259	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAP3K20:Ponatinib)	-
31261	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112748	6885	RP1-154G14.1	MAP3K7	MEKK7|TAK1|TGF1a	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAP3K7:Ponatinib)	-
31263	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAP4K2:Ponatinib)	-
31265	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAP4K5:Ponatinib)	-
31267	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAPK14:Ponatinib)	-
31269	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- PDK1:Ponatinib)	-
31271	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- PDK2:Ponatinib)	-
31273	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- PDK3:Ponatinib)	-
31275	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- RIPK1:Ponatinib)	-
31277	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- RIPK2:Ponatinib)	-
31279	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- SRC:Ponatinib)	-
31281	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- STK10:Ponatinib)	-
31283	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119490	51347	-	TAOK3	DPK|JIK|MAP3K18	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- TAOK3:Ponatinib)	-
31285	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- YES1:Ponatinib)	-
31287	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1---ABL1:GNF-7)	-
31289	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- ABL2:GNF-7)	-
31291	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- BLK:GNF-7)	-
31293	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CDK11B:GNF-7)	-
31295	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CDK4:GNF-7)	-
31297	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116290	11113	-	CIT	CRIK|STK21	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CIT:GNF-7)	-
31299	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CSK:GNF-7)	-
31301	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- EPHA3:GNF-7)	-
31303	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- FER:GNF-7)	-
31305	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- GAK:GNF-7)	-
31307	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1---a LCK:GNF-7)	-
31309	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- LIMK2:GNF-7)	-
31311	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP3K20:GNF-7)	-
31313	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112748	6885	RP1-154G14.1	MAP3K7	MEKK7|TAK1|TGF1a	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP3K7:GNF-7)	-
31315	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K1:GNF-7)	-
31317	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K2:GNF-7)	-
31319	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K5:GNF-7)	-
31321	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK14:GNF-7)	-
31323	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK7:GNF-7)	-
31325	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK9:GNF-7)	-
31327	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31329	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31331	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127209	149420	RP11-96L14.4	PDIK1L	CLIK1L|STK35L2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- PDIK1L:GNF-7)	-
31333	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- PTK2B:GNF-7)	-
31335	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- RIPK1:GNF-7)	-
31337	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31339	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- SIK2:GNF-7)	-
31341	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- STK35:GNF-7)	-
31343	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114750	9344	UNQ2971/PRO7431	TAOK2	MAP3K17|PSK|PSK1|PSK1-BETA|TAO1|TAO2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- TAOK2:GNF-7)	-
31345	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- TNK2:GNF-7)	-
31347	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- ULK1:GNF-7)	-
31349	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1---ABL1:GNF-7)	-
31351	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- ABL2:GNF-7)	-
31353	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- BLK:GNF-7)	-
31355	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CDK11B:GNF-7)	-
31357	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CDK4:GNF-7)	-
31359	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CSK:GNF-7)	-
31361	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- EPHA3:GNF-7)	-
31363	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- FER:GNF-7)	-
31365	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- GAK:GNF-7)	-
31367	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- LIMK1:GNF-7)	-
31369	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP3K20:GNF-7)	-
31371	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K1:GNF-7)	-
31373	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K2:GNF-7)	-
31375	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K3:GNF-7)	-
31377	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K5:GNF-7)	-
31379	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK14:GNF-7)	-
31381	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK7:GNF-7)	-
31383	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK8:GNF-7)	-
31385	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK9:GNF-7)	-
31387	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31389	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31391	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- NLK:GNF-7)	-
31393	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127209	149420	RP11-96L14.4	PDIK1L	CLIK1L|STK35L2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- PDIK1L:GNF-7)	-
31395	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- PTK2B:GNF-7)	-
31397	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RIPK1:GNF-7)	-
31399	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31401	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA3:GNF-7)	-
31403	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- SIK2:GNF-7)	-
31405	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- SIK3:GNF-7)	-
31407	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- STK35:GNF-7)	-
31409	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- TNK2:GNF-7)	-
31411	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- ULK1:GNF-7)	-
31413	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide---AAK1:Ceritinib)	-
31415	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- AURKA:Ceritinib)	-
31417	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- AURKB:Ceritinib)	-
31419	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31421	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK12:Ceritinib)	-
31423	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK16:Ceritinib)	-
31425	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK17:Ceritinib)	-
31427	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31429	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK5:Ceritinib)	-
31431	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK7:Ceritinib)	-
31433	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK9:Ceritinib)	-
31435	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CLK1:Ceritinib)	-
31437	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- FER:Ceritinib)	-
31439	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- GSK3A:Ceritinib)	-
31441	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- GSK3B:Ceritinib)	-
31443	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116382	11213	-	IRAK3	ASRT5|IRAKM	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- IRAK3:Ceritinib)	-
31445	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAP3K11:Ceritinib)	-
31447	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31449	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31451	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- NUAK1:Ceritinib)	-
31453	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- PRKAA1:Ceritinib)	-
31455	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- PRKAA2:Ceritinib)	-
31457	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- PTK2B:Ceritinib)	-
31459	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
31461	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
31463	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- STK33:Ceritinib)	-
31465	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- STK38:Ceritinib)	-
31467	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- TTK:Ceritinib)	-
31469	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide---AURKA:AT7519)	-
31471	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- BUB1:AT7519)	-
31473	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- BUB1B:AT7519)	-
31475	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK13:AT7519)	-
31477	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK14:AT7519)	-
31479	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK17:AT7519)	-
31481	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK4:AT7519)	-
31483	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK9:AT7519)	-
31485	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CHEK1:AT7519)	-
31487	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CLK1:AT7519)	-
31489	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CSNK1A1:AT7519)	-
31491	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CSNK1D:AT7519)	-
31493	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107982	1612	-	DAPK1	DAPK	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- DAPK1:AT7519)	-
31495	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108391	2081	-	ERN1	IRE1|IRE1P|IRE1a|hIRE1p	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- ERN1:AT7519)	-
31497	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- GSK3A:AT7519)	-
31499	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- GSK3B:AT7519)	-
31501	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- MAP3K1:AT7519)	-
31503	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- NUAK1:AT7519)	-
31505	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111312	5294	-	PIK3CG	PI3CG|PI3K|PI3Kgamma|PIK3|p110gamma|p120-PI3K	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- PIK3CG:AT7519)	-
31507	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116228	11040	-	PIM2	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- PIM2:AT7519)	-
31509	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- PLK1:AT7519)	-
31511	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120896	55781	-	RIOK2	RIO2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- RIOK2:AT7519)	-
31513	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- STK17A:AT7519)	-
31515	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- STK17B:AT7519)	-
31517	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- TTK:AT7519)	-
31519	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- UHMK1:AT7519)	-
31521	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- WEE1:AT7519)	-
31523	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1---AAK1:Thienopyrimidines)	-
31525	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK1:Thienopyrimidines)	-
31527	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK16:Thienopyrimidines)	-
31529	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK2:Thienopyrimidines)	-
31531	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK4:Thienopyrimidines)	-
31533	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK6:Thienopyrimidines)	-
31535	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	136426	440275	-	EIF2AK4	GCN2|PVOD2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- EIF2AK4:Thienopyrimidines)	-
31537	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- GAK:Thienopyrimidines)	-
31539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- LATS1:Thienopyrimidines)	-
31541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- LIMK2:Thienopyrimidines)	-
31543	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MAPK6:Thienopyrimidines)	-
31545	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114120	8550	-	MAPKAPK5	MAPKAP-K5|MK-5|MK5|PRAK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MAPKAPK5:Thienopyrimidines)	-
31547	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MARK2:Thienopyrimidines)	-
31549	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MARK4:Thienopyrimidines)	-
31551	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MKNK2:Thienopyrimidines)	-
31553	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- NEK9:Thienopyrimidines)	-
31555	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- RPS6KB1:Thienopyrimidines)	-
31557	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- SIK2:Thienopyrimidines)	-
31559	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- SNRK:Thienopyrimidines)	-
31561	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK17A:Thienopyrimidines)	-
31563	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK17B:Thienopyrimidines)	-
31565	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK35:Thienopyrimidines)	-
31567	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- WEE1:Thienopyrimidines)	-
31569	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide---AAK1:TAE684)	-
31571	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- ABL2:TAE684)	-
31573	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- AURKA:TAE684)	-
31575	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- BLK:TAE684)	-
31577	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- BMP2K:TAE684)	-
31579	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK12:TAE684)	-
31581	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK13:TAE684)	-
31583	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK17:TAE684)	-
31585	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK2:TAE684)	-
31587	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK4:TAE684)	-
31589	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK5:TAE684)	-
31591	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK6:TAE684)	-
31593	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK7:TAE684)	-
31595	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK9:TAE684)	-
31597	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- FER:TAE684)	-
31599	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- GAK:TAE684)	-
31601	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- ITK:TAE684)	-
31603	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- LCK:TAE684)	-
31605	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- LIMK2:TAE684)	-
31607	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- PRKAA1:TAE684)	-
31609	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- PTK2B:TAE684)	-
31611	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- RPS6KA1:TAE684)	-
31613	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- SRC:TAE684)	-
31615	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- WEE1:TAE684)	-
31617	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide---AAK1:Thienopyrimidines)	-
31619	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- AURKA:Thienopyrimidines)	-
31621	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- BMP2K:Thienopyrimidines)	-
31623	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123981	84254	-	CAMKK1	CAMKKA	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CAMKK1:Thienopyrimidines)	-
31625	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK16:Thienopyrimidines)	-
31627	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
31629	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
31631	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- EIF2AK2:Thienopyrimidines)	-
31633	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- FER:Thienopyrimidines)	-
31635	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- GAK:Thienopyrimidines)	-
31637	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- LCK:Thienopyrimidines)	-
31639	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- LIMK2:Thienopyrimidines)	-
31641	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110442	4296	-	MAP3K11	MEKK11|MLK-3|MLK3|PTK1|SPRK	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAP3K11:Thienopyrimidines)	-
31643	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK8:Thienopyrimidines)	-
31645	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK9:Thienopyrimidines)	-
31647	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- NEK9:Thienopyrimidines)	-
31649	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- PLK4:Thienopyrimidines)	-
31651	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- PTK2B:Thienopyrimidines)	-
31653	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- SIK2:Thienopyrimidines)	-
31655	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- STK17A:Thienopyrimidines)	-
31657	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- STK17B:Thienopyrimidines)	-
31659	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- ULK1:Thienopyrimidines)	-
31661	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117470	25989	-	ULK3	-	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- ULK3:Thienopyrimidines)	-
31663	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- WEE1:Thienopyrimidines)	-
31665	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10070	Bivalent Ligand 280	DD-02-198|Bivalent_Ligand_280	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DD-02-198 (VHL:VH032---MAPK14:AZ628)	-
31667	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10069	Bivalent Ligand 281	DD-03-171|Bivalent_Ligand_281	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DD-03-171 (CRBN:pomalidomide---BTK:CGI-1746)	-
31669	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10068	Bivalent Ligand 282	DD-04-118|Bivalent_Ligand_282	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DD-04-118 (CRBN:Thalidomide---BTK:CGI-1746)	-
31671	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide---CDK4:TAE684)	-
31673	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- AURKA:TAE684)	-
31675	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- WEE1:TAE684)	-
31677	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- BLK:TAE684)	-
31679	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- FER:TAE684)	-
31681	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK6:TAE684)	-
31683	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- LIMK2:TAE684)	-
31685	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- AAK1:TAE684)	-
31687	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK5:TAE684)	-
31689	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK2:TAE684)	-
31691	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- ITK:TAE684)	-
31693	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK17:TAE684)	-
31695	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- LCK:TAE684)	-
31697	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- PTK2B:TAE684)	-
31699	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK9:TAE684)	-
31701	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK7:TAE684)	-
31703	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK13:TAE684)	-
31705	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- PRKAA1:TAE684)	-
31707	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK12:TAE684)	-
31709	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- BMP2K:TAE684)	-
31711	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- STK10:TAE684)	-
31713	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide---AURKA:Dabrafenib)	-
31715	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- BCKDK:Dabrafenib)	-
31717	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK1:Dabrafenib)	-
31719	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK16:Dabrafenib)	-
31721	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK17:Dabrafenib)	-
31723	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK2:Dabrafenib)	-
31725	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107453	1018	-	CDK3	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK3:Dabrafenib)	-
31727	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK4:Dabrafenib)	-
31729	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK6:Dabrafenib)	-
31731	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- COQ8A:Dabrafenib)	-
31733	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123009	79934	-	ADCK4	NPHS9	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- COQ8B:Dabrafenib)	-
31735	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CSK:Dabrafenib)	-
31737	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- EIF2AK2:Dabrafenib)	-
31739	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- LIMK1:Dabrafenib)	-
31741	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- LIMK2:Dabrafenib)	-
31743	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- MAP3K20:Dabrafenib)	-
31745	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- NLK:Dabrafenib)	-
31747	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- PLK1:Dabrafenib)	-
31749	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- PDK1:Dabrafenib)	-
31751	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- PDK2:Dabrafenib)	-
31753	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115689	10420	-	TESK2	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- TESK2:Dabrafenib)	-
31755	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide---ABL1:PP58 (kinobeads) 212391-57-6)	-
31757	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- ABL2:PP58 (kinobeads) 212391-57-6)	-
31759	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- AURKA:PP58 (kinobeads) 212391-57-6)	-
31761	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- BLK:PP58 (kinobeads) 212391-57-6)	-
31763	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- CSK:PP58 (kinobeads) 212391-57-6)	-
31765	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- EPHA3:PP58 (kinobeads) 212391-57-6)	-
31767	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108365	2051	-	EPHB6	HEP	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- EPHB6:PP58 (kinobeads) 212391-57-6)	-
31769	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- FYN:PP58 (kinobeads) 212391-57-6)	-
31771	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- GAK:PP58 (kinobeads) 212391-57-6)	-
31773	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- LCK:PP58 (kinobeads) 212391-57-6)	-
31775	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- LIMK2:PP58 (kinobeads) 212391-57-6)	-
31777	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- MAPK14:PP58 (kinobeads) 212391-57-6)	-
31779	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- NLK:PP58 (kinobeads) 212391-57-6)	-
31781	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- PDK1:PP58 (kinobeads) 212391-57-6)	-
31783	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114544	9088	-	PKMYT1	MYT1|PPP1R126	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- PKMYT1:PP58 (kinobeads) 212391-57-6)	-
31785	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- SIK2:PP58 (kinobeads) 212391-57-6)	-
31787	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- SRC:PP58 (kinobeads) 212391-57-6)	-
31789	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- TNK2:PP58 (kinobeads) 212391-57-6)	-
31791	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- WEE1:PP58 (kinobeads) 212391-57-6)	-
31793	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- YES1:PP58 (kinobeads) 212391-57-6)	-
31795	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide---AAK1:TAE684)	-
31797	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- AURKA:TAE684)	-
31799	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- BLK:TAE684)	-
31801	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK12:TAE684)	-
31803	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK17:TAE684)	-
31805	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK2:TAE684)	-
31807	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK4:TAE684)	-
31809	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK5:TAE684)	-
31811	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK6:TAE684)	-
31813	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK7:TAE684)	-
31815	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK9:TAE684)	-
31817	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- FER:TAE684)	-
31819	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- ITK:TAE684)	-
31821	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- LCK:TAE684)	-
31823	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- LIMK2:TAE684)	-
31825	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- PTK2B:TAE684)	-
31827	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- STK10:TAE684)	-
31829	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- WEE1:TAE684)	-
31831	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide---CDK4:GNF-7)	-
31833	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- BLK:GNF-7)	-
31835	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- FER:GNF-7)	-
31837	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- LIMK2:GNF-7)	-
31839	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- GAK:GNF-7)	-
31841	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- CSK:GNF-7)	-
31843	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- SIK2:GNF-7)	-
31845	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- LCK:GNF-7)	-
31847	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- PTK2B:GNF-7)	-
31849	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- SRC:GNF-7)	-
31851	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- ABL2:GNF-7)	-
31853	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
31855	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide---a MAPK9:GNF-7)	-
31857	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAP4K2:GNF-7)	-
31859	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MKNK2:GNF-7)	-
31861	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAP3K20:GNF-7)	-
31863	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- TNK2:GNF-7)	-
31865	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide---BLK:GNF-7)	-
31867	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- CDK4:GNF-7)	-
31869	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- CLK1:GNF-7)	-
31871	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- CSK:GNF-7)	-
31873	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- FER:GNF-7)	-
31875	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- LCK:GNF-7)	-
31877	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- LIMK1:GNF-7)	-
31879	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
31881	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
31883	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MKNK2:GNF-7)	-
31885	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- PLK1:GNF-7)	-
31887	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- PTK2B:GNF-7)	-
31889	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- SIKa2:GNF-7)	-
31891	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- SRC:GNF-7)	-
31893	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- TNK2:GNF-7)	-
31895	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- UHMK1:GNF-7)	-
31897	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113357	7525	-	YES1	HsT441|P61-YES|Yes|c-yes	9606	Homo sapiens	target	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- YES1:GNF-7)	-
31899	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide---AAK1:MRT68921)	-
31901	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- AURKA:MRT68921)	-
31903	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- AURKB:MRT68921)	-
31905	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- BMP2K:MRT68921)	-
31907	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- CDK10:MRT68921)	-
31909	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- CDK9:MRT68921)	-
31911	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- GAK:MRT68921)	-
31913	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- MARK2:MRT68921)	-
31915	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- MARK3:MRT68921)	-
31917	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- MARK4:MRT68921)	-
31919	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- SIK2:MRT68921)	-
31921	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- STK17A:MRT68921)	-
31923	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- STK17B:MRT68921)	-
31925	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- SNRK:MRT68921)	-
31927	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- ULK1:MRT68921)	-
31929	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- WEE1:MRT68921)	-
31931	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide---AURKA:Ceritinib)	-
31933	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK1:Ceritinib)	-
31935	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK12:Ceritinib)	-
31937	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK16:Ceritinib)	-
31939	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK17:Ceritinib)	-
31941	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK2:Ceritinib)	-
31943	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK4:Ceritinib)	-
31945	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK5:Ceritinib)	-
31947	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK6:Ceritinib)	-
31949	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK7:Ceritinib)	-
31951	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK9:Ceritinib)	-
31953	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK10:Ceritinib)	-
31955	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK8:Ceritinib)	-
31957	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK9:Ceritinib)	-
31959	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- RPS6KA1:Ceritinib)	-
31961	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide---AAK1:TAE684)	-
31963	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- AURKA:TAE684)	-
31965	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- BLK:TAE684)	-
31967	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK12:TAE684)	-
31969	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK17:TAE684)	-
31971	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK2:TAE684)	-
31973	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK5:TAE684)	-
31975	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK7:TAE684)	-
31977	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK9:TAE684)	-
31979	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- FER:TAE684)	-
31981	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- ITK:TAE684)	-
31983	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- LCK:TAE684)	-
31985	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- LIMK2:TAE684)	-
31987	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- PTK2B:TAE684)	-
31989	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- WEE1:TAE684)	-
31991	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide---CDK4:Dinaciclib)	-
31993	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- WEE1:Dinaciclib)	-
31995	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- STK17A:Dinaciclib)	-
31997	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- PLK1:Dinaciclib)	-
31999	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- BUB1:Dinaciclib)	-
32001	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- TTK:Dinaciclib)	-
32003	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- UHMK1:Dinaciclib)	-
32005	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- MAP3K1:Dinaciclib)	-
32007	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- BUB1B:Dinaciclib)	-
32009	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120896	55781	-	RIOK2	RIO2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- RIOK2:Dinaciclib)	-
32011	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- NUAK1:Dinaciclib)	-
32013	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116228	11040	-	PIM2	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- PIM2:Dinaciclib)	-
32015	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- CSNK1A1:Dinaciclib)	-
32017	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide---AAK1:APY-24)	-
32019	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- AURKA:APY-24)	-
32021	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- AURKB:APY-24)	-
32023	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- BMP2K:APY-24)	-
32025	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- CDK9:APY-24)	-
32027	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- EPHB2:APY-24)	-
32029	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- GSK3B:APY-24)	-
32031	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- ITK:APY-24)	-
32033	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- LATS1:APY-24)	-
32035	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- MAP4K2:APY-24)	-
32037	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- NEK9:APY-24)	-
32039	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115586	10298	-	PAK4	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- PAK4:APY-24)	-
32041	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- PLK4:APY-24)	-
32043	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- STK17B:APY-24)	-
32045	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide---CDK14:not specified)	-
32047	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- CSNK1A1:not specified)	-
32049	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- CSNK1D:not specified)	-
32051	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107838	1454	RP1-5O6.1	CSNK1E	CKIepsilon|HCKIE	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- CSNK1E:not specified)	-
32053	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- GSK3A:not specified)	-
32055	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- GSK3B:not specified)	-
32057	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- LIMK2:not specified)	-
32059	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- MAP3K1:not specified)	-
32061	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119075	50488	-	MINK1	B55|MAP4K6|MINK|YSK2|ZC3|hMINK|hMINKbeta	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- MINK1:not specified)	-
32063	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- NUAK1:not specified)	-
32065	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115586	10298	-	PAK4	-	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- PAK4:not specified)	-
32067	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116228	11040	-	PIM2	-	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- PIM2:not specified)	-
32069	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112669	6793	-	STK10	LOK|PRO2729	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- STK10:not specified)	-
32071	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- STK17B:not specified)	-
32073	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- STK35:not specified)	-
32075	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112665	6789	-	STK4	KRS2|MST1|TIIAC|YSK3	9606	Homo sapiens	target	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- STK4:not specified)	-
32077	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide---AAK1:Thienopyrimidines)	-
32079	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- AURKA:Thienopyrimidines)	-
32081	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123981	84254	-	CAMKK1	CAMKKA	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CAMKK1:Thienopyrimidines)	-
32083	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
32085	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
32087	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- LIMK2:Thienopyrimidines)	-
32089	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- NEK9:Thienopyrimidines)	-
32091	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- PTK2B:Thienopyrimidines)	-
32093	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- STK17A:Thienopyrimidines)	-
32095	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- STK17B:Thienopyrimidines)	-
32097	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- ULK1:Thienopyrimidines)	-
32099	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117470	25989	-	ULK3	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- ULK3:Thienopyrimidines)	-
32101	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- WEE1:Thienopyrimidines)	-
32103	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1---AAK1:MRT68921)	-
32105	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- GAK:MRT68921)	-
32107	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK2:MRT68921)	-
32109	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK3:MRT68921)	-
32111	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK4:MRT68921)	-
32113	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- RPS6KB1:MRT68921)	-
32115	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SIK2:MRT68921)	-
32117	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SIK3:MRT68921)	-
32119	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SNRK:MRT68921)	-
32121	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- STK17A:MRT68921)	-
32123	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- STK17B:MRT68921)	-
32125	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- ULK1:MRT68921)	-
32127	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- WEE1:MRT68921)	-
32129	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide---AURKA:Ceritinib)	-
32131	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- AURKB:Ceritinib)	-
32133	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
32135	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
32137	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK5:Ceritinib)	-
32139	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
32141	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
32143	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- PTK2:Ceritinib)	-
32145	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
32147	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
32149	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- STK33:Ceritinib)	-
32151	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- TTK:Ceritinib)	-
32153	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide---ABL1:TX1-85-1)	-
32155	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- ABL2:TX1-85-1)	-
32157	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- AURKA:TX1-85-1)	-
32159	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- BLK:TX1-85-1)	-
32161	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- CSK:TX1-85-1)	-
32163	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107838	1454	RP1-5O6.1	CSNK1E	CKIepsilon|HCKIE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- CSNK1E:TX1-85-1)	-
32165	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- FYN:TX1-85-1)	-
32167	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- LATS1:TX1-85-1)	-
32169	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- LCK:TX1-85-1)	-
32171	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- LIMK1:TX1-85-1)	-
32173	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111593	5607	-	MAP2K5	HsT17454|MAPKK5|MEK5|PRKMK5	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- MAP2K5:TX1-85-1)	-
32175	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- SRC:TX1-85-1)	-
32177	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1---AAK1:TG101209)	-
32179	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- CDK16:TG101209)	-
32181	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- WEE1:TG101209)	-
32183	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- GAK:TG101209)	-
32185	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- MARK4:TG101209)	-
32187	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- NEK9:TG101209)	-
32189	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- RPS6KB1:TG101209)	-
32191	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SIK2:TG101209)	-
32193	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SIK3:TG101209)	-
32195	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SNRK:TG101209)	-
32197	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- STK17A:TG101209)	-
32199	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- STK17B:TG101209)	-
32201	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide---ABL1:TX1-85-1)	-
32203	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- ABL2:TX1-85-1)	-
32205	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- BLK:TX1-85-1)	-
32207	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107838	1454	RP1-5O6.1	CSNK1E	CKIepsilon|HCKIE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- CSNK1E:TX1-85-1)	-
32209	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- CSK:TX1-85-1)	-
32211	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- FYN:TX1-85-1)	-
32213	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- LATS1:TX1-85-1)	-
32215	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- LCK:TX1-85-1)	-
32217	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- LIMK1:TX1-85-1)	-
32219	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111593	5607	-	MAP2K5	HsT17454|MAPKK5|MEK5|PRKMK5	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- MAP2K5:TX1-85-1)	-
32221	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- SRC:TX1-85-1)	-
32223	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide---BLK:Quizartinib)	-
32225	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- CDK5:Quizartinib)	-
32227	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- FER:Quizartinib)	-
32229	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- GAK:Quizartinib)	-
32231	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109863	3654	-	IRAK1	IRAK|pelle	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- IRAK1:Quizartinib)	-
32233	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- LCK:Quizartinib)	-
32235	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- MAP4K2:Quizartinib)	-
32237	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- MAPK14:Quizartinib)	-
32239	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- RIPK1:Quizartinib)	-
32241	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- SRC :Quizartinib)	-
32243	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide---CDK14:not specified)	-
32245	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- CSNK1D:not specified)	-
32247	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- GSK3A:not specified)	-
32249	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- GSK3B:not specified)	-
32251	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- NUAK1:not specified)	-
32253	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116228	11040	-	PIM2	-	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- PIM2:not specified)	-
32255	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- STK17B:not specified)	-
32257	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- STK35:not specified)	-
32259	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112665	6789	-	STK4	KRS2|MST1|TIIAC|YSK3	9606	Homo sapiens	target	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- STK4:not specified)	-
32261	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide---COQ8A:Adavosertib)	-
32263	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- MKNK2:Adavosertib)	-
32265	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115586	10298	-	PAK4	-	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PAK4:Adavosertib)	-
32267	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PDK1:Adavosertib)	-
32269	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PDK2:Adavosertib)	-
32271	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PDK3:Adavosertib)	-
32273	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111570	5584	-	PRKCI	DXS1179E|PKCI|nPKC-iota	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PRKCI:Adavosertib)	-
32275	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125042	93627	HSPC302	TBCK	TBCKL	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- TBCK:Adavosertib)	-
32277	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- WEE1:Adavosertib)	-
32279	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative---BLK:GNF-7)	-
32281	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107164	699	-	BUB1	BUB1A|BUB1L|hBUB1	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- BUB1:GNF-7)	-
32283	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- CDK4:GNF-7)	-
32285	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- LIMK2:GNF-7)	-
32287	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- SIK2:GNF-7)	-
32289	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- STK17A:GNF-7)	-
32291	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- TEC:GNF-7)	-
32293	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- TNK2:GNF-7)	-
32295	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- UHMK1:GNF-7)	-
32297	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide---AURKA:PND-1186)	-
32299	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- CDK10:PND-1186)	-
32301	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- CDK7:PND-1186)	-
32303	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- MAPK7:PND-1186)	-
32305	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- PTK2B:PND-1186)	-
32307	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- RPS6KA1:PND-1186)	-
32309	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- RPS6KA3:PND-1186)	-
32311	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- STK33:PND-1186)	-
32313	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- WEE1:PND-1186)	-
32315	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide---BCKDK:Palbociclib)	-
32317	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK4:Palbociclib)	-
32319	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32321	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- COQ8A:Palbociclib)	-
32323	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- PDK1:Palbociclib)	-
32325	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- PDK2:Palbociclib)	-
32327	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- PDK3:Palbociclib)	-
32329	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- WEE1:Palbociclib)	-
32331	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide---AAK1:kinobeads)	-
32333	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- AURKA:kinobeads)	-
32335	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- AURKB:kinobeads)	-
32337	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- CDK6:kinobeads)	-
32339	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- CDK9:kinobeads)	-
32341	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108554	2263	-	FGFR2	BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- FGR2:kinobeads)	-
32343	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- STK17A:kinobeads)	-
32345	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- TTK:kinobeads)	-
32347	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	609064	728642	RP1-283E3.2	CDK11A	CDC2L2|CDC2L3|CDK11-p110|CDK11-p46|CDK11-p58|PITSLRE|p58GTA	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide---CDK11A:AT7519)	-
32349	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- CDK9:AT7519)	-
32351	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- CLK1:AT7519)	-
32353	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- GSK3A:AT7519)	-
32355	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- GSK3B:AT7519)	-
32357	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111312	5294	-	PIK3CG	PI3CG|PI3K|PI3Kgamma|PIK3|p110gamma|p120-PI3K	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- PIK3CG:AT7519)	-
32359	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- SGK3:AT7519)	-
32361	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide---AURKA:PND-1186)	-
32363	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- NUAK1:PND-1186)	-
32365	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- PTK2B:PND-1186)	-
32367	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- RPS6KA1:PND-1186)	-
32369	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- RPS6KA3:PND-1186)	-
32371	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122426	65975	-	STK33	-	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- STK33:PND-1186)	-
32373	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- WEE1:PND-1186)	-
32375	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide---BCKDK:Ribociclib)	-
32377	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK4:Ribociclib)	-
32379	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK6:Ribociclib)	-
32381	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- COQ8A:Ribociclib)	-
32383	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- PDK1:Ribociclib)	-
32385	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- PDK2:Ribociclib)	-
32387	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- PDK3:Ribociclib)	-
32389	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide---ABL2:Ibrutinib)	-
32391	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- BLK:Ibrutinib)	-
32393	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- CSK:Ibrutinib)	-
32395	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108810	2534	RP1-66H14.1	FYN	SLK|SYN|p59-FYN	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- FYN:Ibrutinib)	-
32397	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- LCK:Ibrutinib)	-
32399	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- SRC:Ibrutinib)	-
32401	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112865	7006	-	TEC	PSCTK4	9606	Homo sapiens	target	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- TEC:Ibrutinib)	-
32403	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide---BLK:Vemurafenib)	-
32405	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide--- CSK:Vemurafenib)	-
32407	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide--- LCK:Vemurafenib)	-
32409	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide--- LIMK2:Vemurafenib)	-
32411	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111593	5607	-	MAP2K5	HsT17454|MAPKK5|MEK5|PRKMK5	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide--- MAP2K5:Vemurafenib)	-
32413	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9989	Bivalent Ligand 311	dRAF-3|Bivalent_Ligand_311	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: dRAF-3 (CRBN:Thalidomide--- MAP3K20 :Vemurafenib)	-
32415	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide---AKT1:Ipatasertib)	-
32417	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- AKT2:Ipatasertib)	-
32419	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- AKT3:Ipatasertib)	-
32421	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- CDK4:Ipatasertib)	-
32423	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- MAPK6:Ipatasertib)	-
32425	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- STK17A :Ipatasertib)	-
32427	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TL13-178 (CRBN:pomalidomide---CDK4:Ponatininb)	-
32429	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- LIMK1:Ponatininb)	-
32431	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- MAP3K20:Ponatininb)	-
32433	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- MAPK14:Ponatininb)	-
32435	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9994	Bivalent Ligand 314	ZNL-03-127|Bivalent_Ligand_314	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: ZNL-03-127 (CRBN:pomalidomide---BLK:XMD8-87)	-
32437	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9994	Bivalent Ligand 314	ZNL-03-127|Bivalent_Ligand_314	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: ZNL-03-127 (CRBN:pomalidomide--- LIMK1:XMD8-87)	-
32439	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9994	Bivalent Ligand 314	ZNL-03-127|Bivalent_Ligand_314	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: ZNL-03-127 (CRBN:pomalidomide--- LIMK2:XMD8-87)	-
32441	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9994	Bivalent Ligand 314	ZNL-03-127|Bivalent_Ligand_314	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: ZNL-03-127 (CRBN:pomalidomide--- STK17A:XMD8-87)	-
32443	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide---BCKDK:Dabrafenib)	-
32445	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121312	56997	PP265	ADCK3	ARCA2|CABC1|COQ10D4|COQ8|SCAR9	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- COQ8A:Dabrafenib)	-
32447	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- LIMK1:Dabrafenib)	-
32449	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- PDK1:Dabrafenib)	-
32451	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- PDK2:Dabrafenib)	-
32453	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- PDK3:Dabrafenib)	-
32455	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9996	Bivalent Ligand 316	INY-02-164|Bivalent_Ligand_316	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: INY-02-164 (CRBN:Thalidomide---AKT1:Ipatasertib)	-
32457	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9996	Bivalent Ligand 316	INY-02-164|Bivalent_Ligand_316	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: INY-02-164 (CRBN:Thalidomide--- AKT2:Ipatasertib)	-
32459	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9996	Bivalent Ligand 316	INY-02-164|Bivalent_Ligand_316	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: INY-02-164 (CRBN:Thalidomide--- AKT3:Ipatasertib)	-
32461	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9996	Bivalent Ligand 316	INY-02-164|Bivalent_Ligand_316	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115583	10295	-	BCKDK	BCKDKD|BDK	9606	Homo sapiens	target	Standardized BVL Name: INY-02-164 (CRBN:Thalidomide--- BCKDK:Ipatasertib)	-
32463	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-118 (CRBN:Thalidomide---AAK1:TG101209)	-
32465	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: JWG-118 (CRBN:Thalidomide--- AURKA:TG101209)	-
32467	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: JWG-118 (CRBN:Thalidomide--- BMP2K:TG101209)	-
32469	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: JWG-118 (CRBN:Thalidomide--- GAK:TG101209)	-
32471	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9987	Bivalent Ligand 318	SB1-G-190|Bivalent_Ligand_318	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-190 (CRBN:Thalidomide---AAK1:APY-24)	-
32473	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9987	Bivalent Ligand 318	SB1-G-190|Bivalent_Ligand_318	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-190 (CRBN:Thalidomide--- AURKA:APY-24)	-
32475	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9987	Bivalent Ligand 318	SB1-G-190|Bivalent_Ligand_318	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-190 (CRBN:Thalidomide--- BMP2K:APY-24)	-
32477	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9987	Bivalent Ligand 318	SB1-G-190|Bivalent_Ligand_318	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: SB1-G-190 (CRBN:Thalidomide--- GSK3A:APY-24)	-
32479	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-204 (CRBN:thalidomide---CDK4:Palbociclib)	-
32481	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- CDK6:Palbociclib)	-
32483	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- PDK1:Palbociclib)	-
32485	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- WEE1:Palbociclib)	-
32487	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10138	Bivalent Ligand 320	DB-3-291|Bivalent_Ligand_320	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB-3-291 (CRBN:thalidomide---ABL2:dasatinib)	-
32489	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10138	Bivalent Ligand 320	DB-3-291|Bivalent_Ligand_320	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB-3-291 (CRBN:thalidomide--- BLK:dasatinib)	-
32491	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10138	Bivalent Ligand 320	DB-3-291|Bivalent_Ligand_320	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB-3-291 (CRBN:thalidomide--- CSK:dasatinib)	-
32493	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10138	Bivalent Ligand 320	DB-3-291|Bivalent_Ligand_320	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: DB-3-291 (CRBN:thalidomide--- WEE1:dasatinib)	-
32495	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1---ABL2:not specified)	-
32497	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- EPHB2:not specified)	-
32499	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- SIK2:not specified)	-
32501	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- TYK2:not specified)	-
32503	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- CDK17:Dabrafenib)	-
32505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- LIMK1:Dabrafenib)	-
32507	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- LIMK2:Dabrafenib)	-
32509	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32511	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32513	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide--- WEE1:Palbociclib)	-
32515	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10134	Bivalent Ligand 324	INY-01-140-1|Bivalent_Ligand_324	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111189	5163	-	PDK1	-	9606	Homo sapiens	target	Standardized BVL Name: INY-01-140-1 (CRBN:Thalidomide---PDK1:MK-2206)	-
32517	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10134	Bivalent Ligand 324	INY-01-140-1|Bivalent_Ligand_324	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111190	5164	-	PDK2	PDHK2|PDKII	9606	Homo sapiens	target	Standardized BVL Name: INY-01-140-1 (CRBN:Thalidomide--- PDK2:MK-2206)	-
32519	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10134	Bivalent Ligand 324	INY-01-140-1|Bivalent_Ligand_324	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111191	5165	-	PDK3	CMTX6|GS1-358P8.4	9606	Homo sapiens	target	Standardized BVL Name: INY-01-140-1 (CRBN:Thalidomide--- PDK3:MK-2206)	-
32521	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10135	Bivalent Ligand 325	TL13-12|Bivalent_Ligand_325	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: TL13-12 (CRBN:pomalidomide---AURKA:TAE684)	-
32523	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10135	Bivalent Ligand 325	TL13-12|Bivalent_Ligand_325	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL13-12 (CRBN:pomalidomide--- FER:TAE684)	-
32525	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10135	Bivalent Ligand 325	TL13-12|Bivalent_Ligand_325	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111572	5586	RP5-905H16.1	PKN2	PAK2|PRK2|PRKCL2|PRO2042|Pak-2|STK7	9606	Homo sapiens	target	Standardized BVL Name: TL13-12 (CRBN:pomalidomide--- PRK2:TAE684)	-
32527	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10136	Bivalent Ligand 326	JWG-120|Bivalent_Ligand_326	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-120 (CRBN:Thalidomide---AAK1:not specified)	-
32529	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10136	Bivalent Ligand 326	JWG-120|Bivalent_Ligand_326	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: JWG-120 (CRBN:Thalidomide--- AURKA:not specified)	-
32531	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10137	Bivalent Ligand 327	INY-04-125-01|Bivalent_Ligand_327	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: INY-04-125-01 (VHL:VHL-1--- LATS1:MK-2206)	-
32533	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10137	Bivalent Ligand 327	INY-04-125-01|Bivalent_Ligand_327	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: INY-04-125-01 (VHL:VHL-1--- STK17A:MK-2206)	-
32535	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10142	Bivalent Ligand 328	JWG-122|Bivalent_Ligand_328	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-122 (VHL:VHL-1---AAK1:TG101209)	-
32537	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10142	Bivalent Ligand 328	JWG-122|Bivalent_Ligand_328	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: JWG-122 (VHL:VHL-1--- GAK:TG101209)	-
32539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10143	Bivalent Ligand 329	ZZ-1-31B|Bivalent_Ligand_329	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: ZZ-1-31B (VHL:VH032---CDK9:SNS032)	-
32541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10143	Bivalent Ligand 329	ZZ-1-31B|Bivalent_Ligand_329	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: ZZ-1-31B (VHL:VH032---CLK1:SNS032)	-
32543	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10117	Bivalent Ligand 330	TL13-112|Bivalent_Ligand_330	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: TL13-112 (CRBN:pomalidomide---FER:TAE684)	-
32545	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10117	Bivalent Ligand 330	TL13-112|Bivalent_Ligand_330	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: TL13-112 (CRBN:pomalidomide--- PTK2:TAE684)	-
32547	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10117	Bivalent Ligand 330	TL13-112|Bivalent_Ligand_330	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: TL13-112 (CRBN:pomalidomide---RPS6KA1:TAE684)	-
32549	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32551	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK6:Palbociclib)	-
32553	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---WEE1:Palbociclib)	-
32555	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xu C (2021)	34469831	232212	10115	Bivalent Ligand 332	Bivalent_Ligand_332	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120250	54904	DC28	WHSC1L1	NSD3|pp14328	9606	Homo sapiens	target	Standardized BVL Name: MS9715 (VHL:VHL1-Me---NSD3:BI-9321)	-
32557	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gama-Brambila RA (2021)	34048672	232264	10114	Bivalent Ligand 333	Bivalent_Ligand_333	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117017	23451	-	SF3B1	Hsh155|MDS|PRP10|PRPF10|SAP155|SF3b155	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-O4I2 (CRBN:Thalidomide---SF3B1:O4I2)	-
32559	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yan S (2021)	34093856	232273	10110	Bivalent ligand 334	dCeMM4|Bivalent_ligand_334	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	target	Standardized BVL Name: Nano-MP@PSI (VHL:Nano-MP@PSI---MDMX:Nano-MP@PSI)	-
32561	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qu X (2021)	33773286	232265	10113	Bivalent Ligand 335	Bivalent_Ligand_335	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: SIAIS125 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32563	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qu X (2021)	33773286	232265	10112	Bivalent Ligand 336	Bivalent_Ligand_336	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: SIAIS126 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32565	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu R (2021)	34700270	232271	10111	Bivalent Ligand 337	Bivalent_Ligand_337	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WWL0245 (CRBN:thalidomide---BRD4:WNY0824)	-
32567	123251	80344	GL014	DCAF11	PRO2389|WDR23	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang X (2021)	33783207	232094	10121	Bivalent Ligand 338	21-SLF|Bivalent_Ligand_338	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: 21-SLF (DCAF11:not specified---FKBP12:SLF)	-
32569	123251	80344	GL014	DCAF11	PRO2389|WDR23	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang X (2021)	33783207	232094	10120	Bivalent Ligand 339	21-ARL|Bivalent_Ligand_339	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: 21-ARL (DCAF11:not specified---AR:AR ligand)	-
32571	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---SMARCA2:AU-15139)	-
32573	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---SMARCA4:AU-15139)	-
32575	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120490	55193	-	PBRM1	BAF180|PB1	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---PBRM1:AU-15139)	-
32577	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Huber ME (2021)	34936714	232717	10099	Bivalent Ligand 341	13|Bivalent_Ligand_341	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116017	10803	-	CCR9	CC-CKR-9|CDw199|GPR-9-6|GPR28	9606	Homo sapiens	target	Standardized BVL Name: 13 (VHL:(S,R,S)-AHPC---CCR9:vercirnon)	-
32579	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang C (2021)	34927316	232727	10096	Bivalent Ligand 342	SPNCOX|Bivalent_Ligand_342	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	111714	5742	RP11-542K23.6	PTGS1	COX1|COX3|PCOX1|PES-1|PGG/HS|PGHS-1|PGHS1|PHS1|PTGHS	9606	Homo sapiens	target	Standardized BVL Name: SPNCOX (VHL:GSGSALAPYIP---PTGS1:indomethacin)	-
32581	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang C (2021)	34927316	232727	10096	Bivalent Ligand 342	SPNCOX|Bivalent_Ligand_342	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	target	Standardized BVL Name: SPNCOX (VHL:GSGSALAPYIP---PTGS2:indomethacin)	-
32583	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lu X (2021)	34916494	232728	10097	Bivalent Ligand 343	XL5-VHL-2|Bivalent_Ligand_343	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	target	Standardized BVL Name: XL5-VHL-2 (VHL:VHL ligand---ADRM1:XL5)	-
32585	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lu Y (2021)	34885822	232750	10102	Bivalent Ligand 344	21a|Bivalent_Ligand_344	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: 21a(CRBN:lenalidomide---HDAC6:benzamide)	-
32587	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32589	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32591	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32593	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2021)	34100597	232747	10100	Bivalent Ligand 346	Bivalent_Ligand_346	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111902	5970	-	RELA	NFKB3|p65	9606	Homo sapiens	target	Standardized BVL Name: NF-kB-PROTAC (dNF-kB)(VHL:VHLL-X-BCN---RELA:N3-ODN)	-
32595	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2021)	34100597	232747	10101	Bivalent Ligand 347	Bivalent_Ligand_347	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108201	1869	-	E2F1	E2F-1|RBAP1|RBBP3|RBP3	9606	Homo sapiens	target	Standardized BVL Name: E2F-PROTAC (dE2F) (VHL:VHLL-X-BCN---E2F1:N3-ODN)	-
32597	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cao Z (2021)	34860497	239580	10105	Bivalent Ligand 348	14a|Bivalent_Ligand_348	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: 14a (CRBN:pomalidomide---HDAC6:indirubin)	-
32599	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT1:GDC-0068)	-
32601	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT2:GDC-0068)	-
32603	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT3:GDC-0068)	-
32605	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10078	Bivalent Ligand 350	MS170|Bivalent_Ligand_350	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: MS170 (CRBN:pomalidomide---AKT1:GDC-0068)	-
32607	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10078	Bivalent Ligand 350	MS170|Bivalent_Ligand_350	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: MS170 (CRBN:pomalidomide---AKT2:GDC-0068)	-
32609	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10078	Bivalent Ligand 350	MS170|Bivalent_Ligand_350	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: MS170 (CRBN:pomalidomide---AKT3:GDC-0068)	-
32611	114397	8878	-	SQSTM1	A170|OSIL|PDB3|ZIP3|p60|p62|p62B	9606	Homo sapiens	degradation	lysosome-targeting protein	Zheng ZG (2021)	32432943	233272	10077	Bivalent Ligand 351	lycorine|Bivalent_Ligand_351	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	116596	22937	PSEC0227	SCAP	-	9606	Homo sapiens	target	Standardized BVL Name: lycorine (SQSTM1:lycorine---SCAP:lycorine)	-
32613	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10080	Bivalent Ligand 352	ORN3P1|Bivalent_Ligand_352	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN3P1 (VHL:HIF1a peptide---LIN28A:AGGAGAU)	-
32615	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10079	Bivalent Ligand 353	ORN7P1|Bivalent_Ligand_353	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN7P1 (VHL:HIF1a peptide---LIN28A:AGGAGAUAACU)	-
32617	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10074	Bivalent Ligand 354	ORN9P1|Bivalent_Ligand_354	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120107	54715	-	RBFOX1	2BP1|A2BP1|FOX-1|FOX1|HRNBP1	9606	Homo sapiens	target	Standardized BVL Name: ORN9P1 (VHL:HIF1a peptide---RBFOX1:UGCAUGU)	-
32619	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10073	Bivalent Ligand 355	ORN3VH032|Bivalent_Ligand_355	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN3VH032 (VHL:VH032---LIN28A:AGGAGAU)	-
32621	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu H (2021)	34217059	233625	10076	Bivalent Ligand 356	SIAIS056|Bivalent_Ligand_356	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SIAIS056 (CRBN:pomalidomide---BCR-ABL:dasatinib)	-
32623	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nguyen TT (2022)	35335338	234961	10075	Bivalent Ligand 357	ARV-110|Bivalent_Ligand_357	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARV-110/bavdegalutamide (CRBN:Thalidomide 5-fluoride---AR:enzalutamide ligand)	-
32625	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lv D (2021)	34824248	234973	10072	Bivalent Ligand 358	753b|Bivalent_Ligand_358	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 753b (VHL:VHL ligand---BCL2L1:ABT263)	-
32627	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lv D (2021)	34824248	234973	10072	Bivalent Ligand 358	753b|Bivalent_Ligand_358	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	target	Standardized BVL Name: 753b (VHL:VHL ligand---BCL2:ABT263)	-
32629	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cao S (2021)	34694800	235015	10071	Bivalent Ligand 359	PROTAC 1|Bivalent_Ligand_359	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: PROATC 1 (CRBN:pomalidomide---FLT3:dovitinib)	-
32631	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cao S (2021)	34694800	235015	10046	Bivalent Ligand 360	PROTAC 2|Bivalent_Ligand_360	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: PROATC 2 (CRBN:pomalidomide---FLT3:dovitinib)	-
32633	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Eron SJ (2021)	34582690	235023	10047	Bivalent Ligand 361	CFT-1297|Bivalent_Ligand_361	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CFT-1297 (CRBN:thalidomide---BRD4:triazoloazepine ligand)	-
32635	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roberts BL (2020)	32255606	235043	10048	Bivalent Ligand 362	AM-A3|Bivalent_Ligand_362	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: AM-A3 (VHL:VHL ligand---ER:raloxifene)	-
32637	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	He K (2020)	32317208	235047	10049	Bivalent Ligand 363	PROTAC 16c|Bivalent_Ligand_363	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 16c (CRBN:lenalidomide---EGFR:osimertinib)	-
32639	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Law RP (2021)	34416073	239581	10050	Bivalent Ligand 364	GSK215|Bivalent_Ligand_364	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: GSK215 (VHL:VHL-021 ---PTK2:VS-4718)	-
32641	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lin X (2020)	32829249	223472	10051	Bivalent Ligand 365	ARV-471|Bivalent_Ligand_365	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ARV-471(CRBN:lenalidomide---ESR1:Lasofoxifene)	-
32643	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10052	Bivalent Ligand 367	AGB1|Bivalent_Ligand_367	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB1 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32645	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10044	Bivalent Ligand 368	AGB2|Bivalent_Ligand_368	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB2 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32647	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10045	Bivalent Ligand 369	AGB3|Bivalent_Ligand_369	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB3 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32649	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Silva MC (2022)	35317195	235160	10028	Bivalent Ligand 370	QC-01-175|Bivalent_Ligand_370	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: QC-01-175 (CRBN:pomalidomide---MAPT:T807)	-
32651	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Silva MC (2022)	35317195	235160	10027	Bivalent Ligand 371	FMF-06-049|Bivalent_Ligand_371	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-049 (CRBN:pomalidomide---MAPT:T807)	-
32653	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Silva MC (2022)	35317195	235160	10026	Bivalent Ligand 372	FMF-06-038|Bivalent_Ligand_372	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-038 (CRBN:pomalidomide---MAPT:T807)	-
32655	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC1:CI-994)	-
32657	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC2:CI-994)	-
32659	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC3:CI-994)	-
32661	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC1:CI-994)	-
32663	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC2:CI-994)	-
32665	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC3:CI-994)	-
32667	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10031	Bivalent Ligand 375	JPS036|Bivalent_Ligand_375	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS036 (VHL:fluorinated cyclopropane VHL analogue---HDAC3:CI-994)	-
32669	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Q (2022)	34864330	235159	10030	Bivalent Ligand 376	BP3|Bivalent_Ligand_376	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109552	3320	-	HSP90AA1	EL52|HSP86|HSP89A|HSP90A|HSP90N|HSPC1|HSPCA|HSPCAL1|HSPCAL4|HSPN|Hsp89|Hsp90|LAP-2|LAP2	9606	Homo sapiens	target	Standardized BVL Name: BP3 (CRBN:pomalidomide---HSP90AA1:BIIB021)	-
32671	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---JAK2:ruxolitinib)	-
32673	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---JAK2:baricitinib)	-
32675	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---JAK2:ruxolitinib N-propyl analog)	-
32677	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10007	Bivalent Ligand 380	compound 8|Bivalent_Ligand_380	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: compound 8 (CRBN:thalidomide---JAK2:baricitinib)	-
32679	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---JAK1:ruxolitinib)	-
32681	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109921	3718	-	JAK3	JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---JAK3:ruxolitinib)	-
32683	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---GSPT1:ruxolitinib)	-
32685	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---IKZF1:ruxolitinib)	-
32687	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (CRBN:pomalidomide---TYK2:ruxolitinib)	-
32689	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---JAK1:baricitinib)	-
32691	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109921	3718	-	JAK3	JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---JAK3:baricitinib)	-
32693	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---GSPT1:baricitinib)	-
32695	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---IKZF1:baricitinib)	-
32697	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	target	Standardized BVL Name: compound 6 (CRBN:pomalidomide---TYK2:baricitinib)	-
32699	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---JAK1:ruxolitinib N-propyl analog)	-
32701	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109921	3718	-	JAK3	JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---JAK3:ruxolitinib N-propyl analog)	-
32703	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---GSPT1:ruxolitinib N-propyl analog)	-
32705	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---IKZF1:ruxolitinib N-propyl analog)	-
32707	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (CRBN:pomalidomide---TYK2:ruxolitinib N-propyl analog)	-
32709	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Adhikari B (2020)	32989298	235317	10007	Bivalent Ligand 380	compound 8|Bivalent_Ligand_380	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: JB158 (CRBN:thalidomide---AURKA:alisertib)	-
32711	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Adhikari B (2020)	32989298	235317	10008	Bivalent Ligand 381	JB170|Bivalent_Ligand_381	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: JB170 (CRBN:thalidomide---AURKA:alisertib)	-
32713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Shen Y (2020)	32787082	235326	10118	Bivalent Ligand 382	compound 15|Bivalent_Ligand_382	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115688	10419	-	PRMT5	HRMT1L5|IBP72|JBP1|SKB1|SKB1Hs	9606	Homo sapiens	target	Standardized BVL Name: compound 15 (VHL:VHL-2---PRMT5:EPZ015666)	-
32715	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2019)	30990042	235710	10133	Bivalent Ligand 383	ERD-308|Bivalent_Ligand_383	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ERD-308 (VHL:compound 11---ESR1:raloxifene)	-
32717	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK1:TL13-87)	-
32719	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
32721	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
32723	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107455	1020	-	CDK5	PSSALRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK5:TL13-87)	-
32725	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
32727	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK7:TL13-87)	-
32729	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107458	1024	-	CDK8	K35	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK8:TL13-87)	-
32731	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK9:TL13-87)	-
32733	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK10:TL13-87)	-
32735	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116725	23097	RP11-346C16.5	CDK19	CDC2L6|CDK11|bA346C16.3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK11:TL13-87)	-
32737	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK12:TL13-87)	-
32739	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK13:TL13-87)	-
32741	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111239	5218	-	CDK14	PFTAIRE1|PFTK1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK14:TL13-87)	-
32743	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK16:TL13-87)	-
32745	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK17:TL13-87)	-
32747	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111156	5129	RP11-288G13.1	CDK18	PCTAIRE|PCTAIRE3|PCTK3	9606	Homo sapiens	target	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK18:TL13-87)	-
32749	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang J (2022)	35210568	236436	9999	Bivalent ligand 384	MS177|Bivalent_ligand_384	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: MS177 (CRBN:pomalidomide --- EZH2:C24)	-
32751	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EZH2:EED226)	-
32753	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EED:EED226)	-
32755	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- SUZ12:EED226)	-
32757	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Durbin AD (2022)	34772733	236045	9997	Bivalent ligand 386	JQAD1|Bivalent_ligand_386	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	target	Standardized BVL Name: JQAD1 (CRBN:pomalidomide --- EP300:A485)	-
32759	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yamanaka S (2022)	35013300	235958	9998	Bivalent ligand 387	5-hydroxythalidomide|Bivalent_ligand_387	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: 5-hydroxythalidomide (CRBN:5-hydroxythalidomide --- GSPT1:5-hydroxythalidomide)	-
32761	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yamanaka S (2022)	35013300	235958	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- GSPT1:CC-885)	-
32763	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yamanaka S (2022)	35013300	235958	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	113534	7750	RP11-264J4.7	ZMYM2	FIM|MYM|RAMP|SCLL|ZNF198	9606	Homo sapiens	target	Standardized BVL Name: pomalidomide (CRBN:pomalidomide --- ZMYM2:pomalidomide)	-
32765	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yamanaka S (2022)	35013300	235958	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121643	57592	RP11-126K1.3	ZNF687	-	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- ZNF687:CC-885)	-
32767	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yamanaka S (2022)	35013300	235958	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- CSNK1A1:CC-885)	-
32769	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Shimizu N (2021)	34764413	235318	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	113498	7704	-	ZBTB16	PLZF|ZNF145	9606	Homo sapiens	target	Standardized BVL Name: pomalidomide (CRBN:pomalidomide --- ZBTB16:pomalidomide)	-
32771	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2021)	34520194	236464	10082	Bivalent ligand 389	MS83|Bivalent_ligand_389	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: MS83 (KEAP1:KEAP1-L --- BRD4:unspecified)	-
32773	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2021)	34520194	236464	10082	Bivalent ligand 389	MS83|Bivalent_ligand_389	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: MS83 (KEAP1:KEAP1-L --- BRD3:unspecified)	-
32775	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Y (2020)	31991291	227147	10094	Bivalent ligand 390	Cer/Pom-PEG@GNPs|Bivalent_ligand_390	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: Cer/Pom-PEG@GNPs (CRBN:pomalidomide --- ALK:ceritinib)	-
32777	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gockel LM (2022)	35128717	236481	10093	Bivalent ligand 391	PROTAC35|Bivalent_ligand_391	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC35 (CRBN:pomalidomide --- AR:enzalutamide)	-
32779	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Salami J (2018)	30271980	239582	10147	Bivalent ligand 392	ARCC-4|Bivalent_ligand_392	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARCC-4 (VHL:HIF-1alpha hydroxyproline derived small molecule --- AR:enzalutamide)	-
32781	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	He S (2021)	34221872	233411	10146	Bivalent ligand 393	PROTAC 11a-1|Bivalent_ligand_393	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 11a-1 (MDM2:Nutlin-3 derivative compound 2 --- MDM2:Nutlin-3 derivative compound 2)	-
32783	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2020)	32865967	229378	10149	Bivalent ligand 394	ZXH-1-161|Bivalent_ligand_394	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: ZXH-1-161 (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
32785	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2020)	32865967	229378	10148	Bivalent ligand 395	ZXH-1-084|Bivalent_ligand_395	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: ZXH-1-084 (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
32787	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2020)	32865967	229378	10151	Bivalent ligand 396	ZXH-1-167|Bivalent_ligand_396	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: ZXH-1-167 (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
32789	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2020)	32865967	229378	10150	Bivalent ligand 397	ZXH-2-160|Bivalent_ligand_397	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: ZXH-2-160 (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
32791	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Powell CE (2020)	32865967	229378	10153	Bivalent ligand 398	ZXH-2-164|Bivalent_ligand_398	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: ZXH-2-164 (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
32793	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Cotton AD (2021)	33395526	231300	10152	Bivalent ligand 399	AC-1|Bivalent_ligand_399	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: AC-1 (RNF43:RNF43 ab, R0 clone --- CD274:atezolizumab)	-
32795	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10123	Bivalent ligand 400	R3/atz|Bivalent_ligand_400	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: R3/atz (RNF43:RNF43 ab, R3 clone --- CD274:atezolizumab)	-
32797	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10122	Bivalent ligand 401	R6/atz|Bivalent_ligand_401	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: R6/atz (RNF43:RNF43 ab, R6 clone --- CD274:atezolizumab)	-
32799	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10125	Bivalent ligand 402	R0/ctx|Bivalent_ligand_402	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: R0/ctx (RNF43:RNF43 ab, R0 clone --- EGFR:cetuximab)	-
32801	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10124	Bivalent ligand 403	R0/matu|Bivalent_ligand_403	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: R0/matu (RNF43:RNF43 ab, R0 clone --- EGFR:matuzumab)	-
32803	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10127	Bivalent ligand 404	R0/neci|Bivalent_ligand_404	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: R0/neci (RNF43:RNF43 ab, R0 clone --- EGFR:necitumumab)	-
32805	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10126	Bivalent ligand 405	R0/pani|Bivalent_ligand_405	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: R0/pani (RNF43:RNF43 ab, R0 clone --- EGFR:panitumumab)	-
32807	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10129	Bivalent ligand 406	R3/ctx|Bivalent_ligand_406	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: R3/ctx  (RNF43:RNF43 ab, R3 clone --- EGFR:cetuximab)	-
32809	123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10128	Bivalent ligand 407	Z18/atz|Bivalent_ligand_407	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: Z18/atz (ZNRF3:Z18 --- CD274:atezolizumab)	-
32811	123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	degradation	recruited e3 ligase	Gosavi PM (2022)	35505873	237057	10131	Bivalent ligand 408	Z18/ctx|Bivalent_ligand_408	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: Z18/ctx (ZNRF3:Z18 --- EGFR:cetuximab)	-
32813	114343	8816	-	DCAF5	BCRG2|BCRP2|D14S1461E|WDR22	9606	Homo sapiens	degradation	recruited e3 ligase	Nalawansha DA (2022)	35311258	239583	10130	Bivalent ligand 409	KL-4|Bivalent_ligand_409	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: KL-4 (DCAF5:L3MBTL3-UNC1215 --- FKBP1A:SLF)	-
32815	114343	8816	-	DCAF5	BCRG2|BCRP2|D14S1461E|WDR22	9606	Homo sapiens	degradation	recruited e3 ligase	Nalawansha DA (2022)	35311258	239583	10108	Bivalent ligand 410	KL-7|Bivalent_ligand_410	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: KL-7  (DCAF5:L3MBTL3-UNC1215 --- BRD2:JQ1)	-
32817	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lu J (2022)	35084180	239584	10109	Bivalent ligand 411	8e|Bivalent_ligand_411	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: 8e (CRBN:lenalidomide ---TTK:TTK inhibitor 6)	-
32819	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lu J (2022)	35084180	239584	10104	Bivalent ligand 412	8j|Bivalent_ligand_412	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113123	7272	RP3-357D13.2	TTK	CT96|ESK|MPH1|MPS1|MPS1L1|PYT	9606	Homo sapiens	target	Standardized BVL Name: 8j (CRBN:lenalidomide ---TTK:TTK inhibitor 6)	-
32821	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Alcock LJ (2022)	35300081	239585	10107	Bivalent ligand 413	PROTAC11/SJ10542|Bivalent_ligand_413	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC11/SJ10542 (CRBN:phenyl glutarimide --- JAK2:baricitinib)	-
32823	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Alcock LJ (2022)	35300081	239585	10107	Bivalent ligand 413	PROTAC11/SJ10542|Bivalent_ligand_413	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109921	3718	-	JAK3	JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC11/SJ10542 (CRBN:phenyl glutarimide --- JAK3:baricitinib)	-
32825	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond MJ (2020)	32875077	239586	10095	Bivalent ligand 414	LC-2|Bivalent_ligand_414	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: LC-2 (VHL:HIF-1alpha hydroxyproline derived small molecule --- KRAS-G12c:MRTX849)	-
32827	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Guo L (2022)	35397401	239587	10132	Bivalent ligand 415	LG-AR-14|Bivalent_ligand_415	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: LG-AR-14 (VHL:VHL ligand --- AR:AR ligand 3)	-
32829	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Guo L (2022)	35397401	239587	9988	Bivalent ligand 416	LG-BRD-12|Bivalent_ligand_416	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: LG-BRD-12 (VHL:VHL ligand --- BRD4:JQ1)	-
32831	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32833	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10154	Bivalent ligand 418	compound 35|Bivalent_ligand_418	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: compound 35 (CRBN:pomalidomide --- AKT:AZD5363)	-
32835	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32837	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10154	Bivalent ligand 418	compound 35|Bivalent_ligand_418	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: compound 35 (CRBN:pomalidomide --- AKT:AZD5363)	-
32839	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32841	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10154	Bivalent ligand 418	compound 35|Bivalent_ligand_418	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: compound 35 (CRBN:pomalidomide --- AKT:AZD5363)	-
32843	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li X (2022)	35395864	239589	10119	Bivalent ligand 419	compound 1|Bivalent_ligand_419	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110444	4298	-	MLLT1	ENL|LTG19|YEATS1	9606	Homo sapiens	target	Standardized BVL Name: compound 1 (CRBN:thalidomide --- MLLT1:SGC-iMLLT)	-
32845	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Pillow TH (2020)	31674143	239590	10060	Bivalent ligand 420	GNE-987|Bivalent_ligand_420	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: GNE-987 ( VHL:VHL-1 --- BRD4:BET inhibitor)	-
32847	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang H (2022)	35344835	239591	10059	Bivalent ligand 421	HL-8|Bivalent_ligand_421	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	target	Standardized BVL Name: HL-8(VHL:VHL ligand --- PIK3CA:compound 15a)	-
32849	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10058	Bivalent ligand 422	WJ638|Bivalent_ligand_422	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: WJ638 (VHL: VH032 --- VHL: VH032)	-
32851	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10057	Bivalent ligand 423	WJ051|Bivalent_ligand_423	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ051  (VHL: VH032 --- BRD4:JQ1)	-
32853	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10056	Bivalent ligand 424	WJ281|Bivalent_ligand_424	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ281  (VHL: VH032 --- BRD4:JQ1)	-
32855	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10055	Bivalent ligand 425	WJ287|Bivalent_ligand_425	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ287  (VHL: VH032 --- BRD4:JQ1)	-
32857	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reddi RN (2021)	34817989	239592	10054	Bivalent ligand 426	CoLDR PROTAC 1n|Bivalent_ligand_426	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: CoLDR PROTAC 1n (CRBN:thalidomide --- BTK)	-
32859	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huber AD (2022)	35978691	238928	10053	Bivalent ligand 427	SJPYT-195|Bivalent_ligand_427	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: SJPYT-195 (CRBN:SJPYT-195 --- GSPT1:SJPYT-195)	-
32862	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	inhibitor	target	Rao G (2018)	30280096	242985	10178	CLEFMA	CLEFMA|4-[3,5-Bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidinyl]-4-oxo-2-butenoic acid|(2Z)-4-[(3E,5E)-3,5-Bis(2-chlorobenzylidene)-4-oxo-1-piperidinyl]-4-oxo-2-butenoic acid|2-Butenoic acid, 4-[(3E,5E)-3,5-bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidinyl]-4-oxo-, (2Z)-	-	CHEMSPIDER	26351206	C23H17Cl2NO4	small molecule	-	1246964-32-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ABOUDPJRQGWQNW-GGDLZHBGSA-N
32863	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	inhibitor	target	Rao G (2018)	30280096	242985	10244	EF24	4-Piperidinone, 3,5-bis[(2-fluorophenyl)methylene]-, (3E,5E)-, hydrochloride (1:1)|(3E,5E)-3,5-Bis(2-fluorobenzylidene)-4-piperidinone hydrochloride (1:1)	-	CHEMSPIDER	88296132	C19H16ClF2NO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ILMJCEBAMHGBAA-XETSTSIRSA-N
32868	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Tao Y (2022)	36170674	241674	10355	Bivalent ligand 428	YT41R|Bivalent_ligand_428	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: YT41R (DCAF1:MY-1B --- FKBP12:SLF)	-
32870	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Tao Y (2022)	36170674	241674	10353	Bivalent ligand 429	YT47R|Bivalent_ligand_429	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: YT47R (DCAF1:MY-1B --- FKBP12:SLF)	-
32872	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Tao Y (2022)	36170674	241674	10370	Bivalent ligand 430	YT117R|Bivalent_ligand_430	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: YT117R (DCAF1:MY-1B ---BRD4:JQ1)	-
32874	115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	degradation	recruited e3 ligase	Henning NJ (2022)	34994556	235307	10371	Bivalent ligand 431	NJH-1-106|Bivalent_ligand_431	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: NJH-1-106 (FEM1B:EN106 ---BRD4:JQ1)	-
32876	115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	degradation	recruited e3 ligase	Henning NJ (2022)	34994556	235307	10372	Bivalent ligand 432	NJH-2-142|Bivalent_ligand_432	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: NJH-2-142 (FEM1B:EN106 ---ABL1:dasatinib)	-
32878	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lier S (2022)	34838332	242581	10373	Bivalent ligand 433	MDEG-541|Bivalent_ligand_433	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	target	Standardized BVL Name: MDEG-541  (CRBN:thalidomide --- MYC:10058-F4)	-
32880	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng KW (2021)	33976200	242625	10366	Bivalent ligand 434	VHL-12VC1.2 fusion|Bivalent_ligand_434	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL12VC1.2 fusion (VHL --- KRAS(G12C):12VC1.2)	-
32882	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng KW (2021)	33976200	242625	10367	Bivalent ligand 435	VHL-12VC1.1 fusion|Bivalent_ligand_435	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL12VC1.1 fusion (VHL --- KRAS(G12C):12VC1.1)	-
32884	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10368	Bivalent ligand 436	VHL-aGFP16 AdPROM|Bivalent_ligand_436	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-aGFP16 AdPROM (VHL:aGFP16 --- KRAS:GFP)	-
32886	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10369	Bivalent ligand 437	VHL-aHRAS AdPROM|Bivalent_ligand_437	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-aHRAS AdPROM (VHL --- KRAS:aHRAS)	-
32888	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10369	Bivalent ligand 437	VHL-aHRAS AdPROM|Bivalent_ligand_437	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: VHL-aHRAS AdPROM (VHL --- HRAS:aHRAS)	-
32890	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- KRAS:iDAB RAS)	-
32892	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- HRAS:iDAB RAS)	-
32894	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- NRAS:iDAB RAS)	-
32896	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- KRAS:iDAB RAS)	-
32898	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- HRAS:iDAB RAS)	-
32900	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- NRAS:iDAB RAS)	-
32902	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10402	Bivalent ligand 440	VHL-iDAb RAS|Bivalent_ligand_440	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-iDAb RAS (VHL --- KRAS:iDAB RAS)	-
32904	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10402	Bivalent ligand 440	VHL-iDAb RAS|Bivalent_ligand_440	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: VHL-iDAb RAS (VHL --- NRAS:iDAB RAS)	-
32906	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10401	Bivalent ligand 441	VHL-DP KRAS|Bivalent_ligand_441	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-DP KRAS (VHL --- KRAS:DARPin K19)	-
32908	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10404	Bivalent ligand 442	xcexb2TrCP-vhhGFP4|Bivalent_ligand_442	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: TrCP-vhhGFP4 (BTRC:vhhGFP4 --- KRAS:GFP)	-
32910	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10403	Bivalent ligand 443	FBW7-vhhGFP4|Bivalent_ligand_443	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: FBW7-vhhGFP4 (FBW7:vhhGFP4 --- KRAS:GFP)	-
32912	112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10398	Bivalent ligand 444	SKP2-vhhGFP4|Bivalent_ligand_444	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: SKP2-vhhGFP4 (SKP2:vhhGFP4 --- KRAS:GFP4)	-
32914	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10397	Bivalent ligand 445	SPOP-vhhGFP4|Bivalent_ligand_445	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: SPOP-vhhGFP4 (SPOP:vhhGFP4 --- KRAS:GFP)	-
32916	114362	8835	-	SOCS2	CIS2|Cish2|SOCS-2|SSI-2|SSI2|STATI2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10400	Bivalent ligand 446	SOCS2-vhhGFP4|Bivalent_ligand_446	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: SOCS2-vhhGFP4 (SOCS2:vhhGFP4 --- KRAS:GFP)	-
32918	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10399	Bivalent ligand 447	CHIP-vhhGFP4|Bivalent_ligand_447	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: CHIP-vhhGFP4 (STUB1:vhhGFP4 --- KRAS:GFP)	-
32920	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10409	Bivalent ligand 448	NS1-SPOP|Bivalent_ligand_448	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: NS1-SPOP (SPOP --- KRAS:NS1)	-
32922	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10408	Bivalent ligand 449	K27-SPOP|Bivalent_ligand_449	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: K27-SPOP (SPOP --- KRAS:DARPin K27)	-
32924	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10408	Bivalent ligand 449	K27-SPOP|Bivalent_ligand_449	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: K27-SPOP (SPOP --- HRAS:DARPin K27)	-
32926	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10408	Bivalent ligand 449	K27-SPOP|Bivalent_ligand_449	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: K27-SPOP (SPOP --- NRAS:DARPin K27)	-
32928	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10379	Bivalent ligand 450	R11.1.6-SPOP|Bivalent_ligand_450	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: R11.1.6-SPOP (SPOP --- KRAS:R11.1.1)	-
32930	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10374	Bivalent ligand 451	K27-VHL|Bivalent_ligand_451	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: K27-VHL (VHL --- KRAS:DARPin K27)	-
32932	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10359	Bivalent ligand 452	K19-SPOP|Bivalent_ligand_452	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: K19-SPOP (SPOP --- KRAS:DARPin K19 )	-
32934	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen P (2021)	34455300	243005	10365	Bivalent ligand 453	4f|Bivalent_ligand_453	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107925	1545	-	CYP1B1	CP1B|CYPIB1|GLC3A|P4501B1	9606	Homo sapiens	target	Standardized BVL Name: 4f (CRBN:thalidomide --- CYP1B1:-naphthoflavone)	-
32936	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2022)	34959180	243006	10385	Bivalent ligand 454	PF15|Bivalent_ligand_454	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: PF15 (CRBN:lenalidomide --- FLT3:compound 9b)	-
32938	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK6:palbociclib)	-
32940	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10377	Bivalent ligand 456	SAB355|Bivalent_ligand_456	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: SAB355 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32942	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10382	Bivalent ligand 457	CST837|Bivalent_ligand_457	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: CST837 (CRBN:thalidomide --- CDK6:palbociclib)	-
32944	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32946	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK4:palbociclib)	-
32948	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: SAB401 (CRBN:thalidomide --- IZKF3:palbociclib)	-
32950	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang L (2023)	35015337	246241	10380	Bivalent ligand 504	PZ15227|Bivalent_ligand_504	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: PZ15227 (CRBN:pomalidomide --- BCL2L1:ABT263)	-
32952	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qu L (2021)	34649182	243029	10381	Bivalent ligand 505	PT-65|Bivalent_ligand_505	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109186	2931	-	GSK3A	-	9606	Homo sapiens	target	Standardized BVL Name: PT-65 (CRBN:pomalidomide --- GSK3A:AZD2858)	-
32954	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qu L (2021)	34649182	243029	10381	Bivalent ligand 505	PT-65|Bivalent_ligand_505	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: PT-65 (CRBN:pomalidomide --- GSK3B:AZD2858)	-
32956	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10361	Bivalent ligand 459	PROTAC 34|Bivalent_ligand_459	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 34 (VHL:modified VH298 --- CDK6:palbociclib)	-
32958	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32960	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10418	Bivalent ligand 460	PROTAC 11|Bivalent_ligand_460	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 11 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32962	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK6:palbociclib)	-
32964	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK4:palbociclib)	-
32966	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK4:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK4:palbociclib)	-
32968	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK6:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK6:palbociclib)	-
32970	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hansen JD (2020)	32130004	246242	10413	Bivalent ligand 462	CC-92480|Bivalent_ligand_462	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CC-92480 (mezigdomide) (CRBN: CC-92480 (mezigdomide) --- IKZF3: CC-92480 (mezigdomide))	-
32972	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hansen JD (2020)	32130004	246242	10413	Bivalent ligand 462	CC-92480|Bivalent_ligand_462	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: CC-92480 (mezigdomide) (CRBN: CC-92480 (mezigdomide) --- IKZF1: CC-92480 (mezigdomide))	-
32974	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Matyskiela ME (2018)	28425720	207534	10411	Bivalent ligand 463	CC-220|Bivalent_ligand_463	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CC-220 (iberdomide) (CRBN:CC-220 (iberdomide) --- IKZF3: CC-220 (iberdomide))	-
32976	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Matyskiela ME (2018)	28425720	207534	10411	Bivalent ligand 463	CC-220|Bivalent_ligand_463	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: CC-220 (iberdomide) (CRBN:CC-220 (iberdomide) --- IKZF1: CC-220 (iberdomide))	-
32978	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hagner PR (2015)	26002965	185946	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CC-122 (Avadomide) (CRBN:CC-122 (Avadomide) --- IKZF3: CC-122 (Avadomide))	-
32980	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hagner PR (2015)	26002965	185946	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: CC-122 (Avadomide) (CRBN:CC-122 (Avadomide) --- IKZF1: CC-122 (Avadomide))	-
32982	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Mo Z (2021)	33847741	232060	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Standardized BVL Name: CC-122 (Avadomide) (CRBN:CC-122 (Avadomide) --- ZFP91: CC-122 (Avadomide))	-
32984	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase		34027417	232355	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	113534	7750	RP11-264J4.7	ZMYM2	FIM|MYM|RAMP|SCLL|ZNF198	9606	Homo sapiens	target	Standardized BVL Name: CC-122 (Avadomide) (CRBN:CC-122 (Avadomide) --- ZMYM2: CC-122 (Avadomide))	-
32986	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu W (2022)	34936696	246243	10413	Bivalent ligand 462	CC-92480|Bivalent_ligand_462	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	target	Standardized BVL Name: CC-92480 (mezigdomide) (CRBN: CC-92480 (mezigdomide) --- ZFP91: CC-92480 (mezigdomide))	-
32988	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hansen JD (2018)	28358507	246244	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- IKZF3:CC-885)	-
32990	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao M (2021)	33676183	232098	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- CDK4:CC-885)	-
32992	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hao BB (2020)	32210356	246245	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107133	665	-	BNIP3L	BNIP3a|NIX	9606	Homo sapiens	target	Standardized BVL Name: CC-885 (CRBN:CC-885 --- BNIP3L:CC-885)	-
32994	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Surka C (2021)	33197925	229264	10396	Bivalent ligand 464	CC-90009|Bivalent_ligand_464	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: CC-90009 (eragidomide) (CRBN:CC-90009 (eragidomide) --- GSPT1: CC-90009 (eragidomide)	-
32996	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10376	Bivalent ligand 465	BTX-1188|Bivalent_ligand_465	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: BTX-1188 (CRBN:BTX-1188 --- GSPT1:BTX-1188)	-
32998	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10376	Bivalent ligand 465	BTX-1188|Bivalent_ligand_465	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: BTX-1188 (CRBN:BTX-1188 --- IKZF3:BTX-1188)	-
33000	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10376	Bivalent ligand 465	BTX-1188|Bivalent_ligand_465	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: BTX-1188 (CRBN:BTX-1188 --- IKZF1:BTX-1188)	-
33002	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10429	Bivalent ligand 466	CC-91633|Bivalent_ligand_466	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107836	1452	-	CSNK1A1	CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975	9606	Homo sapiens	target	Standardized BVL Name: CC-91633 (BMS-986397) (CRBN:CC-91633 (BMS-986397) --- CSNK1A1:CC-91633 (BMS-986397))	-
33004	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10423	Bivalent ligand 467	CFT7455|Bivalent_ligand_467	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CFT7455 (CRBN:CFT7455 --- IKZF3:CFT7455)	-
33006	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10423	Bivalent ligand 467	CFT7455|Bivalent_ligand_467	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: CFT7455 (CRBN:CFT7455 --- IKZF1:CFT7455)	-
33008	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10407	Bivalent ligand 468	CC-99282|Bivalent_ligand_468	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: CC-99282 (CRBN:CC-99282 --- IKZF3:CC-99282)	-
33010	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Fuchs O (2023)	35933246	246246	10407	Bivalent ligand 468	CC-99282|Bivalent_ligand_468	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: CC-99282 (CRBN:CC-99282 --- IKZF1:CC-99282)	-
33012	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10406	Bivalent ligand 469	NJH-2-057|Bivalent_ligand_469	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	107506	1080	tcag7.78	CFTR	ABC35|ABCC7|CF|CFTR/MRP|MRP7|TNR-CFTR|dJ760C5.1	9606	Homo sapiens	target	Standardized BVL Name: NJH-2-057 (OTUB1:EN523 --- deltaF508-CFTR:lumacaftor)	-
33014	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10358	Bivalent ligand 470	LEB-03-144|Bivalent_ligand_470	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: LEB-03-144 (OTUB1:EN523 --- WEE1:AZD1775)	-
33016	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10375	Bivalent ligand 471	LEB-03-146|Bivalent_ligand_471	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: LEB-03-146 (OTUB1:EN523 --- WEE1:AZD1775)	-
33018	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10394	Bivalent ligand 472	FOXO-DUBTAC #6|Bivalent_ligand_472	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	108598	2309	-	FOXO3	AF6q21|FKHRL1|FKHRL1P2|FOXO2|FOXO3A	9606	Homo sapiens	target	Standardized BVL Name: FOXO-DUBTAC #6 (OTUB1:DUBL-X-BCN --- FOXO3A:N3-ODN)	-
33020	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10410	Bivalent ligand 473	p53-DUBTACs #6|Bivalent_ligand_473	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	target	Standardized BVL Name: p53-DUBTACs #6 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33022	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10428	Bivalent ligand 474	p53-DUBTACs #7|Bivalent_ligand_474	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	target	Standardized BVL Name: p53-DUBTACs #7 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33024	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10417	Bivalent ligand 475	IRF-DUBTAC #7|Bivalent_ligand_475	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	109869	3661	-	IRF3	-	9606	Homo sapiens	target	Standardized BVL Name: IRF-DUBTAC #7 (OTUB1:DUBL-X-BCN --- IRF3:N3-IRF3-ODN)	-
33026	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Shergalis AG (2023)	36656921	245121	10364	Bivalent ligand 476	1a|Bivalent_ligand_476	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: 1a (DCAF16:1a---BRD2:1a)	-
33028	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Shergalis AG (2023)	36656921	245121	10364	Bivalent ligand 476	1a|Bivalent_ligand_476	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 1a (DCAF16:1a---BRD4:1a)	-
33030	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	 (2022)	35491637	246247	10405	Bivalent ligand 477	ARV-766|Bivalent_ligand_477	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARV-766 (CRBN:glutarimide---AR:aryloxy tetramethylcyclobutane)	-
33032	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xiang W (2021)	34473519	246248	10420	Bivalent ligand 478	ARD-2585|Bivalent_ligand_478	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-2585 (CRBN:thalidomide---AR:modified compound 9)	-
33034	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2021)	36046114	246249	10414	Bivalent ligand 479	CC-94676/AR-LDD|Bivalent_ligand_479	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: CC-94676/AR-LDD (CRBN:unspecified---AR:unspecified)	-
33036	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Dobrovolsky D (2019)	30545835	246250	10387	Bivalent ligand 480	DD-03-007|Bivalent_ligand_480	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DD-03-007 (CRBN:thalidomide---BTK:CGI1746)	-
33038	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Dobrovolsky D (2019)	30545835	246250	10386	Bivalent ligand 481	DD-03-171|Bivalent_ligand_481	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DD-03-171 (CRBN:thalidomide---BTK:CGI1746)	-
33040	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Dobrovolsky D (2019)	30545835	246250	10386	Bivalent ligand 481	DD-03-171|Bivalent_ligand_481	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-171 (CRBN:thalidomide---IKZF1:CGI1746)	-
33042	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Dobrovolsky D (2019)	30545835	246250	10386	Bivalent ligand 481	DD-03-171|Bivalent_ligand_481	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: DD-03-171 (CRBN:thalidomide---IKZF3:CGI1746)	-
33044	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	degradation	recruited e3 ligase	Liu TT (2022)	36375317	244515	10412	Bivalent ligand 482	bufalin|Bivalent_ligand_482	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	108202	1870	-	E2F2	E2F-2	9606	Homo sapiens	target	Standardized BVL Name: bufalin (ZFP91:bufalin---E2F2:bufalin)	-
33046	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Su W (2023)	36647763	245466	10388	Bivalent ligand 483	CDTAC CDTAC PD-L1:CRBN|Bivalent_ligand_483	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: CDTAC CDTAC PD-L1:CRBN (CRBN:thalidomide---CD274:BMS-1166)	-
33048	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang L (2022)	36250201	241369	10391	Bivalent ligand 484	ZL216|Bivalent_ligand_484	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110771	4691	-	NCL	C23	9606	Homo sapiens	target	Standardized BVL Name: ZL216 (VHL:AHPC ---NCL:AS1411)	-
33050	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Miao J (2023)	37836790	246251	10390	Bivalent ligand 485	P9|Bivalent_ligand_485	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: P9 (VHL:VHL-2 --- PTPN11:compound 4)	-
33052	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	antiviral	recruited e3 ligase	Desantis J (2021)	34534839	232373	10393	Bivalent ligand 486	PROTAC 3 anti-viral|Bivalent_ligand_486	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123135	80142	RP11-395P17.2	PTGES2	C9orf15|GBF-1|GBF1|PGES2|mPGES-2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3 anti-viral (VHL: HIF-1alpha hydroxyproline derived small molecule---PTGES2:indomethacin; Coronavirus Project)	-
33054	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	antiviral	recruited e3 ligase	Desantis J (2021)	34534839	232373	10392	Bivalent ligand 487	PROTAC 5 anti-viral|Bivalent_ligand_487	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123135	80142	RP11-395P17.2	PTGES2	C9orf15|GBF-1|GBF1|PGES2|mPGES-2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5 anti-viral (VHL: HIF-1alpha hydroxyproline derived small molecule---PTGES2:indomethacin; Coronavirus Project)	-
33062	112615	6737	-	TRIM21	RNF81|RO52|Ro/SSA|SSA|SSA1	9606	Homo sapiens	antiviral	recruited e3 ligase	Chatterjee P (2020)	33230174	239810	10425	Bivalent ligand 491	23-mer|Bivalent_ligand_491	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	4383848	43740568	GU280_gp02	S	spike|SARS-CoV2 S|SARS-CoV2 spike|S protein|surface|SARS-CoV-2 spike|SARS-CoV-2 S|SPIKE_SARS2|PRO_0000449646	2697049	Severe acute respiratory syndrome coronavirus 2	target	The authors fused the RBD-binding proteins to the CHIPTPR modified E3 ubiquitin ligase domain to prevent circumvent the need to express Trim21 in trans|Standardized BVL Name: 23-mer (A2N)-CHIPTPR (TRIM21:NA --- S RBD domain: sACE2 derived 23-mer (A2N) peptide; Coronavirus Project; Target UniProt ID PRO_0000449646 (S))	-
33064	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation/antiviral	recruited e3 ligase	Alugubelli YR (2023)	888800001046	245523	10426	Bivalent ligand 492	antiviral MDP2|Bivalent_ligand_492	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	4383849	43740578	GU280_gp01	ORF1ab	ORF1ab polyprotein|1ab|SARS-CoV2 ORF1ab|SARS-CoV-2 ORF1ab|Replicase|R1AB_SARS2|PRO_0000449618	2697049	Severe acute respiratory syndrome coronavirus 2	target	Standardized BVL Name: antiviral MDP2 (CRBN:thalidomide---Nsp5/MPro:MPI8; Coronavirus Project; Target UniProt ID PRO_0000449623 (nsp5))	-
33066	112615	6737	-	TRIM21	RNF81|RO52|Ro/SSA|SSA|SSA1	9606	Homo sapiens	degradation 	recruited e3 ligase	Fletcher A (2023)	37925433	246254	10427	Bivalent ligand 493	T21RBCC-VHHHuR|Bivalent_ligand_493	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	108309	1994	-	ELAVL1	ELAV1|HUR|Hua|MelG	9606	Homo sapiens	target	Standardized BVL Name: T21RBCC-VHHHuR (TRIM21:NA--- ELAVL1:VHH ab)	-
33068	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10424	Bivalent ligand 494	CIP-1|Bivalent_ligand_494	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-1 (VHL:MZ1---BRD4:BB3-114)	-
33070	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10357	Bivalent ligand 495	CIP-3|Bivalent_ligand_495	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-3 (VHL:MZ1---BRD4:BB2-109)	-
33072	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10422	Bivalent ligand 496	CIP-4|Bivalent_ligand_496	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-4 (VHL:MZ1---BRD4:BB2-109)	-
33074	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10356	Bivalent ligand 497	CIP-22|Bivalent_ligand_497	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: CIP-22 (VHL:MZ1---BRD2:BB2-109)	-
33076	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10395	Bivalent ligand 498	XZ739|Bivalent_ligand_498	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: XZ739 (CRBN: pomalidomide ---BCL-XL:ABT-263)	-
33078	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10421	Bivalent ligand 499	12c|Bivalent_ligand_499	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 12c (CRBN: pomalidomide ---BCL-XL:ABT-263)	-
33080	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10416	Bivalent ligand 500	15a|Bivalent_ligand_500	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 15a (CRBN: pomalidomide ---BCL-XL:ABT-263)	-
33082	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10354	Bivalent ligand 501	16a|Bivalent_ligand_501	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 16a (CRBN: pomalidomide ---BCL-XL:ABT-263)	-
33084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10378	Bivalent ligand 502	6c|Bivalent_ligand_502	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 6c (VHL:VHL ligand ---BCL-XL:ABT-263)	-
33086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32171162	246256	10352	Bivalent ligand 503	14o|Bivalent_ligand_503	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: 14o (VHL:VHL ligand --- EGFRL858R/T790M:XTF-262)	-
33150	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2020)	32408336	223364	8581	NMS-873	Pyridine, 3-[3-(cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-|NMS-873|MFCD28009371|3-[3-Cyclopentylsulfanyl-5-(4'-methanesulfonyl-2-methylbiphenyl-4-yloxymethyl)-[1,2,4]triazol-4-yl]-pyridine|3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-pyridine|3-[3-(Cyclopentylsulfanyl)-5-({[2-methyl-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-4H-1,2,4-triazol-4-yl]pyridine	-	CHEMSPIDER	29398603	C27H28N4O3S2	small molecule	-	1418013-75-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: p97 inhibitor; viral inhibition mechanism undetermined	UJGTUKMAJVCBIS-UHFFFAOYSA-N
33362	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	sars-cov-2 inhibitor	target	Kelch MA (2023)	37342561	241452	10275	PRI-724	PRI-724|N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide|2H-Pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide, hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-	-	CHEMSPIDER	19546236	C33H32N4O4	small molecule	-	847591-62-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: CBP-CTNNB1 interaction inhibitor; CBP interactor; antiviral activity against SARS-CoV-2 Wuhan-Hu-1, Zeta, Epsilon, Kappa, Alpha, Beta, Delta, and Omicron variants, SARS-CoV and MERS	HQWTUOLCGKIECB-UHFFFAOYSA-N
33419	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	sars-cov-2 inhibitor	target	Aviner R (2023)	888800000985	244285	8586	Nimbolide	methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(furan-3-yl)-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b'c']difuran-6-yl]acetate|2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b'c']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-|GY2370000|Methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(3-furyl)-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[b]furo[2',3',4':4,5]naphtho[2,3-d]furan-6-yl]acetate|nimbolide	-	CHEMSPIDER	10320669	C27H30O7	small molecule	-	25990-37-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human RNF114 inhibitor; antiviral activity against SARS-CoV-2 in Vero E6 cells	JZIQWNPPBKFOPT-LSYMHUITSA-N
33445	113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bednash JS (2023)	36730646	245710	8337	C30	1H-Indole-2,3-dione, 5-chloro-1-[(2,5-dichlorophenyl)methyl]-, 3-(O-acetyloxime), (3Z)-|(3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one|LDN57444|LDN-57444|LDN 57444|	-	CHEMSPIDER	21395767	C17H11Cl3N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human UCHL1 deubiquitinase (DUB) inhibitor; ACE2 protein is stabilized by UCHL1 DUB activity that is antagonized by LDN-57444; antiviral activity against SARS-CoV-2 in Calu-3 cells	OPQRFPHLZZPCCH-PGMHBOJBSA-N
33495	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ji J (2023)	36892138	247218	10736	Bivalent ligand 506	ARE-PROTAC C2|bivalent_ligand_506	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110852	4780	-	NFE2L2	NRF2	9606	Homo sapiens	target	Standardized BVL Name: ARE-PROTAC C2 (CRBN:lenalidomide --- NFE2L2:5-TGAG/CNNNGC-3)	-
33497	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Rosenberg SC (2023)	36773603	247269	10737	Bivalent ligand 507	GNE-579|bivalent_ligand_507	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110852	4780	-	NFE2L2	NRF2	9606	Homo sapiens	target	Standardized BVL Name: GNE-579 (VHL:VH032 --- EGFRExon19/L858R:Compound A)	-
33499	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hung CL (2023)	36893587	247251	10738	Bivalent ligand 508	ITRI-90|bivalent_ligand_508	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ITRI-90 (VHL:VHL HCl salt --- AR/AR-V(LBD):AZD3514 )	-
33501	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hung CL (2023)	36893587	247251	10739	Bivalent ligand 509	ITRI-125|bivalent_ligand_509	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ITRI-125 (VHL:VHL HCl salt --- AR/AR-V(LBD):AZD3514 )	-
33503	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hung CL (2023)	36893587	247251	10740	Bivalent ligand 510	ITRI-126|bivalent_ligand_510	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ITRI-126 (CRBN:lenalidomide --- AR/AR-V(LBD):AZD3514 )	-
33505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lee GT (2021)	33277442	229865	10741	Bivalent ligand 511	MTX-23|bivalent_ligand_511	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: MTX-23 (VHL:CRL2VHL compound --- AR/AR-V7:AR DBD binding molecule)	-
33507	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2021)	34431670	256613	10742	Bivalent ligand 512	ARD-2128|bivalent_ligand_512	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-2128 (CRBN:thalidomide --- AR:ARi-184)	-
33509	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	36749666	248602	10743	Bivalent ligand 513	Degrader 13|bivalent_ligand_513	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: Degrader 13 (CRBN: 1,2,3-trisubstituted PDHU --- BRD4:JQ1)	-
33511	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Thomas E (2023)	36831540	248703	10744	Bivalent ligand 514	VNPP433-3b|bivalent_ligand_514	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: VNPP433-3 (MDM2:VNPP433-3 --- AR/AR-V7: VNPP433-3)	-
33513	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10745	Bivalent ligand 515	isoindolinone (EM12)|bivalent_ligand_515	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: isoindolinone (EM12) (CRBN: isoindolinone (EM12) --- IKZF1:isoindolinone (EM12))	-
33515	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10746	Bivalent ligand 516	4-OH-EM12|bivalent_ligand_516	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: 4-OH-EM12 (CRBN:4-OH-EM12 --- IKZF1:4-OH-EM12)	-
33517	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10747	Bivalent ligand 517	5-OH-EM12|bivalent_ligand_517	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: 5-OH-EM12 (CRBN:5-OH-EM12 --- GSPT1:5-OH-EM12)	-
33519	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: lenalidomide (CRBN:lenalidomide --- GSPT1:lenalidomide)	-
33521	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: lenalidomide (CRBN:lenalidomide --- IKZF1:lenalidomide)	-
33523	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10748	Bivalent ligand 518	5-NH2-EM12|bivalent_ligand_518	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: 5-NH2-EM12 (CRBN:5-NH2-EM12 --- IKZF1:5-NH2-EM12)	-
33525	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10749	Bivalent ligand 519	6-NH2-EM12|bivalent_ligand_519	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: 6-NH2-EM12 (CRBN: 6-NH2-EM12 --- IKZF1: 6-NH2-EM12)	-
33527	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: thalidomide (CRBN:thalidomide --- GSPT1:thalidomide)	-
33529	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: thalidomide (CRBN:thalidomide --- IKZF1:thalidomide)	-
33531	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	9998	Bivalent ligand 387	5-hydroxythalidomide|Bivalent_ligand_387	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: 5-hydroxythalidomide (CRBN:5-OH-Thal --- GSPT1:5-OH-Thal)	-
33533	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: pomalidomide (CRBN:pomalidomide --- IKZF1:pomalidomide)	-
33535	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Nowak RP (2023)	36970148	250541	10750	Bivalent ligand 521	5-NH2-Thal|bivalent_ligand_521	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: 5-NH2-Thal (CRBN:5-NH2-Thal --- IKZF1:5-NH2-Thal)	-
33537	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Furihata H (2020)	32929090	228972	9998	Bivalent ligand 387	5-hydroxythalidomide|Bivalent_ligand_387	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	121420	57167	-	SALL4	DRRS|HSAL4|ZNF797|dJ1112F19.1	9606	Homo sapiens	target	Standardized BVL Name: 5-hydroxythalidomide (CRBN: 5-hydroxythalidomide --- SALL4:5-hydroxythalidomide)	-
33539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10751	Bivalent ligand 522	PROTAC-1|bivalent_ligand_522	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-1 (VHL:VH032 --- BRAF:S5)	-
33541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10752	Bivalent ligand 523	PROTAC-2|bivalent_ligand_523	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-2 (VHL:VH032 --- BRAF:S5)	-
33543	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10753	Bivalent ligand 524	PROTAC-3|bivalent_ligand_524	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-3 (VHL:VH032 --- BRAF:S5)	-
33545	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10751	Bivalent ligand 522	PROTAC-1|bivalent_ligand_522	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-1 (VHL:VH032 --- KDR:S5)	-
33547	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10752	Bivalent ligand 523	PROTAC-2|bivalent_ligand_523	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-2 (VHL:VH032 --- KDR:S5)	-
33549	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bouguenina H (2023)	37418539	256614	10754	Bivalent ligand 525	16|bivalent_ligand_525	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: 16 (CRBN:pomalidomide --- BRD9:GSK-3)	-
33551	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bouguenina H (2023)	37418539	256614	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD9: BRDL1)	-
33553	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bouguenina H (2023)	37418539	256614	8503	Bivalent ligand 96	dBRD9|Bivalent_ligand_96	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: Compound 6 (dBRD9) (CRBN:pomalidomide --- BRD9:GSK-3)	-
33555	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bai L (2017)	28209615	256615	10755	Bivalent ligand 526	BETd-246|bivalent_ligand_526	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: BETd-246 (CRBN:thalidomide --- BRD2:BETi-211)	-
33557	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bai L (2017)	28209615	256615	10755	Bivalent ligand 526	BETd-246|bivalent_ligand_526	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: BETd-246 (CRBN:thalidomide --- BRD3:BETi-211)	-
33559	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bai L (2017)	28209615	256615	10755	Bivalent ligand 526	BETd-246|bivalent_ligand_526	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: BETd-246 (CRBN:thalidomide --- BRD4:BETi-211)	-
33561	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Carvalho LAR (2024)	38195841	256612	10756	Bivalent ligand 527	C8|bivalent_ligand_527	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115701	10434	-	LYPLA1	APT-1|APT1|LPL-I|LPL1|hAPT1	9606	Homo sapiens	target	Standardized BVL Name: C8 (CRBN:pomalidomide --- LYPLA1:aryl sulfonyl fluoride reactive group)	-
33563	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Song H (2024)	38194774	256616	10757	Bivalent ligand 528	18a|bivalent_ligand_528	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: 18a (BIRC2:bestatin --- GPX4:RSL3)	-
33565	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2023)	37289649	256617	10758	Bivalent ligand 529	BD-7148|bivalent_ligand_529	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: BD-7148 (CRBN:pomalidomide --- BRD4:QCA276)	-
33567	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2023)	37289649	256617	10759	Bivalent ligand 530	BD-9136|bivalent_ligand_530	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: BD-9136 (CRBN:pomalidomide --- BRD4:QCA276)	-
33569	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2021)	33488968	256618	10760	Bivalent ligand 531	compound 9|bivalent_ligand_531	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- IRAK4:compound 1)	-
33571	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10761	Bivalent ligand 532	DBr-1|bivalent_ligand_532	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: DBr-1 (DCAF1: DCAF1 Binder 13 --- BRD9:BI-9564)	-
33573	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10762	Bivalent ligand 533	DDa-1|bivalent_ligand_533	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DDa-1 (DCAF1: DCAF1 Binder 13 --- CSK:dasatinib)	-
33575	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10762	Bivalent ligand 533	DDa-1|bivalent_ligand_533	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DDa-1 (DCAF1: DCAF1 Binder 13 --- LIMK2:dasatinib)	-
33577	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10762	Bivalent ligand 533	DDa-1|bivalent_ligand_533	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DDa-1 (DCAF1: DCAF1 Binder 13 --- BTK:dasatinib)	-
33579	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10763	Bivalent ligand 534	DBt-5|bivalent_ligand_534	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DBt-5 (DCAF1: DCAF1 Binder 13 --- BTK:BTKi)	-
33581	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10764	Bivalent ligand 535	DBt-10|bivalent_ligand_535	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: DBt-10 (DCAF1: DCAF1 Binder 13 --- BTK:BTKi)	-
33583	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	degradation	recruited e3 ligase	Schroeder M (2024)	38177131	256619	10764	Bivalent ligand 535	DBt-10|bivalent_ligand_535	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DBt-10 (DCAF1: DCAF1 Binder 13 --- LIMK1:BTKi)	-
33585	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	De Dominici M (2020)	32040545	256620	10765	Bivalent ligand 536	YX-2-107|bivalent_ligand_536	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: YX-2-107 (CRBN:thalidomide --- CDK6:palbociclib)	-
33587	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK6:palbociclib)	-
33589	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK4:palbociclib)	-
33591	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Winzker M (2020)	31829492	256621	10767	Bivalent ligand 538	PROTAC 3|bivalent_ligand_538	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111173	5147	-	PDE6D	JBTS22|PDED	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3 (CRBN:pomalidomide --- PDE6D:deltasonamide1)	-
33593	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Winzker M (2020)	31829492	256621	10768	Bivalent ligand 539	PROTAC 5|bivalent_ligand_539	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111173	5147	-	PDE6D	JBTS22|PDED	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5 (VHL:VHL ligand --- PDE6D:deltasonamide1)	-
33595	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang X (2019)	31754664	256622	10769	Bivalent ligand 540	XZ424|bivalent_ligand_540	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: XZ424 (CRBN:pomalidomide --- BCL2L1:compound 3 (A-1155463 derivative))	-
33597	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK6:palbociclib)	-
33599	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK4:palbociclib)	-
33601	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK6:ribociclib)	-
33603	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK4:ribociclib)	-
33605	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ding M (2023)	36563515	256624	10772	Bivalent ligand 543	degrader 8b|bivalent_ligand_543	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: degrader 8b (CRBN:lenalidomide --- BRD4:JQ1)	-
33607	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Y (2021)	33839580	254238	10773	Bivalent ligand 544	Compound 21a|bivalent_ligand_544	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	target	Standardized BVL Name: Compound 21a (CRBN:thalidomide --- PD-L1 :BMS-37 diaryl ether analogue)	-
33609	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li L (2021)	34715575	254240	10774	Bivalent ligand 545	KP-14|bivalent_ligand_545	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: KP-14 (CRBN:pomalidomide --- KRas G12C:KRas G12C-IN-3)	-
33611	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Vemulapalli V (2021)	34411482	254241	10775	Bivalent ligand 546	R1-5C|bivalent_ligand_546	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: R15C (CRBN:pomalidomide --- SHP2:RMC-45503)	-
33613	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Aublette MC (2022)	35231578	254243	10776	Bivalent ligand 547	MA055|bivalent_ligand_547	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MA055 (VHL:VH032 --- Wee1:AZD1775)	-
33615	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Aublette MC (2022)	35231578	254243	10777	Bivalent ligand 548	MA071|bivalent_ligand_548	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MA071 (CRBN:pomalidomide --- Wee1:AZD1775)	-
33617	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37703322	254337	10779	Bivalent ligand 550	compound 3b|bivalent_ligand_550	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115760	10498	-	CARM1	PRMT4	9606	Homo sapiens	target	Standardized BVL Name: compound 3b (VHL:VHL-1 --- CARM1:TP-064)	-
33619	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37703322	254337	10780	Bivalent ligand 551	compound 3e|bivalent_ligand_551	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115760	10498	-	CARM1	PRMT4	9606	Homo sapiens	target	Standardized BVL Name: compound 3e (VHL:VHL-1 --- CARM1:TP-064)	-
33621	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK4:palbociclib)	-
33623	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK6:palbociclib)	-
33625	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116485	22807	-	IKZF2	ANF1A2|HELIOS|ZNF1A2|ZNFN1A2	9606	Homo sapiens	target	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- IKZF2:DKY709)	-
33627	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bonazzi S (2023)	36863346	256626	10782	Bivalent ligand 553	NVP-DKY709|bivalent_ligand_553	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116485	22807	-	IKZF2	ANF1A2|HELIOS|ZNF1A2|ZNFN1A2	9606	Homo sapiens	target	Standardized BVL Name: NVP-DKY709 (CRBN: DKY709 --- IKZF2:DKY709)	-
33629	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu X (2022)	36007011	256627	10783	Bivalent ligand 554	XL01126|bivalent_ligand_554	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	target	Standardized BVL Name: XL01126 (VHL:VH101 --- LRRK2:HG-10-102-01)	-
33631	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qin Q (2022)	35978496	256628	10784	Bivalent ligand 555	PROTAC A13|bivalent_ligand_555	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC A13 (CRBN:pomalidomide --- PTK2:PF-562271 derivative 1)	-
33635	120375	55054	hCG_1817841	ATG16L1	APG16L|ATG16A|ATG16L|IBD10|WDR30	9606	Homo sapiens	degradation	autophagy-targeting protein	Mei L (2023)	37424101	254385	10786	Bivalent ligand 557	QBP-ABP|bivalent_ligand_557	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	109314	3064	-	HTT	HD|IT15	9606	Homo sapiens	target	Standardized BVL Name: QBP-ABP (ATG16L1:ABP --- HTT65Q:QBP)	-
33637	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bhumireddy A (2022)	34767914	254422	10787	Bivalent ligand 558	Compound 6|bivalent_ligand_558	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Compound 6 (VHL:VHL ligand Compound 11 --- AR-V7:VPC-14228)	-
33639	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Shibata N (2022)	35085722	254450	10788	Bivalent ligand 559	Compound 5a/SNIPER(TACC3)-11|bivalent_ligand_559	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	target	Standardized BVL Name: Compound 5a/SNIPER(TACC3)-11 (cIAP1:LCL161 derivative Compound 11 --- FGFR3-TACC3:KHS108)	-
33641	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xiang W (2023)	37683104	254465	10789	Bivalent ligand 560	ARD-1676|bivalent_ligand_560	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-1676 (CRBN:CRBN Ligand 27 --- AR:AR4034)	-
33643	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang L (2021)	34094836	254471	10790	Bivalent ligand 561	Compound 7o|bivalent_ligand_561	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: Compound 7o (CRBN:pomalidomide --- Bcr-Abl:GZD824)	-
33645	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Luo G (2021)	34094835	254500	10791	Bivalent ligand 562	21c|bivalent_ligand_562	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109399	3156	-	HMGCR	LDLCQ3	9606	Homo sapiens	target	Standardized BVL Name: 21c (VHL:VHL231 --- HMGCR:lactone opened lovastatin acid)	-
33647	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Luo G (2021)	34094835	254500	10792	Bivalent ligand 563	21b|bivalent_ligand_563	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109399	3156	-	HMGCR	LDLCQ3	9606	Homo sapiens	target	Standardized BVL Name: 21b (VHL:VHL231 --- HMGCR:lactone lovastatin acid)	-
33649	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2023)	37593574	254507	10793	Bivalent ligand 564	15-271|bivalent_ligand_564	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: 15-271 (CRBN:pomalidomide --- BTK:Ibrutinib)	-
33651	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cheng W (2021)	34788776	254514	10794	Bivalent ligand 565	ha-PROTAC 13|bivalent_ligand_565	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: ha-PROTAC 13 (CRBN:lenalidomide --- EGFRDel19:HALG-gefitinib 4-anilinoquinazoline core)	-
33653	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cheng W (2021)	34788776	254514	10795	Bivalent ligand 566	PROTAC 11|bivalent_ligand_566	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 11 (CRBN:lenalidomide --- EGFRDel19:gefitinib 4-anilinoquinazoline core)	-
33655	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chotitumnavee J (2022)	35311871	254516	10796	Bivalent ligand 567	compound 4c|bivalent_ligand_567	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120968	55869	CDA07	HDAC8	CDLS5|HD8|HDACL1|MRXS6|RPD3|WTS	9606	Homo sapiens	target	Standardized BVL Name: compound 4c (CRBN:pomalidomide --- HDAC8:Compound 2 (NCC-149 analogue))	-
33657	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao C (2023)	37098288	254517	10797	Bivalent ligand 568	CT-4|bivalent_ligand_568	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120968	55869	CDA07	HDAC8	CDLS5|HD8|HDACL1|MRXS6|RPD3|WTS	9606	Homo sapiens	target	Standardized BVL Name: CT-4 (CRBN:pomalidomide --- HDAC8:Compound 4)	-
33659	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xu H (2021)	34124002	254519	10798	Bivalent ligand 569	Compound 3|bivalent_ligand_569	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113222	7376	-	NR1H2	LXR-b|LXRB|NER|NER-I|RIP15|UNR	9606	Homo sapiens	target	Standardized BVL Name: Compound 3 (VHL:VH032 --- LXRB:GW3965)	-
33661	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Lim YS (2023)	36269842	256629	10799	Bivalent ligand 570	UBX-382|bivalent_ligand_570	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: UBX-382 (CRBN:thalidomide --- BTK:novel BTK ligand)	-
33663	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Miao J (2023)	38020389	256630	10800	Bivalent ligand 571	TP1L|bivalent_ligand_571	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111737	5771	-	PTPN2	PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP	9606	Homo sapiens	target	Standardized BVL Name: TP1L (CRBN:lenalidomide --- PTPN2:inhibitor 3)	-
33665	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gazorpak M (2023)	38071198	256631	10801	Bivalent ligand 572	KH-102|bivalent_ligand_572	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109165	2908	-	NR3C1	GCCR|GCR|GCRST|GR|GRL	9606	Homo sapiens	target	Standardized BVL Name: KH-102 (CRBN:lenalidomide --- NR3C1:dexamethasone)	-
33667	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gazorpak M (2023)	38071198	256631	10802	Bivalent ligand 573	KH-103|bivalent_ligand_573	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109165	2908	-	NR3C1	GCCR|GCR|GCRST|GR|GRL	9606	Homo sapiens	target	Standardized BVL Name: KH-103 (CRBN:lenalidomide --- NR3C1:dexamethasone)	-
33669	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Murgai A (2022)	35852517	256632	10803	Bivalent ligand 574	PROTAC 17|bivalent_ligand_574	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 17 (CRBN:thalidomide --- USP7:XL188)	-
33671	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Miller DSJ (2022)	35814929	256633	10804	Bivalent ligand 575	CST905|bivalent_ligand_575	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: CST905 (VHL:VH032 --- BRAF:PLX7683)	-
33673	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wu Y (2022)	35755293	256634	10805	Bivalent ligand 576	PROTAC A7|bivalent_ligand_576	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	target	Standardized BVL Name: PROTAC A7 (VHL:VHL-1 --- NAMPT:MS7)	-
33675	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Swartzel JC (2022)	35749470	256635	10806	Bivalent ligand 577	JCS-1|bivalent_ligand_577	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118787	28960	HSPC015	DCPS	DCS1|HINT-5|HINT5|HSL1	9606	Homo sapiens	target	Standardized BVL Name: JCS-1 (VHL:VL285 --- DCPS:RG3039)	-
33677	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2022)	35717870	256636	10807	Bivalent ligand 578	SYL2158|bivalent_ligand_578	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120250	54904	DC28	WHSC1L1	NSD3|pp14328	9606	Homo sapiens	target	Standardized BVL Name: SYL2158 (VHL:VHL-1 --- NSD3:BI-9321)	-
33679	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Pei Y (2022)	35691827	256637	10808	Bivalent ligand 579	U7D-1|bivalent_ligand_579	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	target	Standardized BVL Name: U7D-1 (CRBN:pomalidomide --- USP7: compound 4)	-
33681	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zeng S (2024)	38086239	256638	10809	Bivalent ligand 580	compound B1|bivalent_ligand_580	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: compound B1 (CRBN:thalidomide --- MAP4K1:compound 1)	-
33683	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yang H (2019)	31769449	256639	10810	Bivalent ligand 581	NH2|bivalent_ligand_581	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: NH2 (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
33685	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33687	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC2:CI-994)	-
33689	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC3:CI-994)	-
33691	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33693	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC2:CI-994)	-
33695	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC3:CI-994)	-
33697	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33699	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC2:CI-994)	-
33701	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC3:CI-994)	-
33703	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yang Z (2021)	34417569	254508	10812	Bivalent ligand 583	GBD-9|bivalent_ligand_583	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: GBD-9 (CRBN:pomalidomide --- BTK:ibrutinib derivative)	-
33705	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yang Z (2021)	34417569	254508	10812	Bivalent ligand 583	GBD-9|bivalent_ligand_583	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: GBD-9 (CRBN:pomalidomide --- GSPT1:ibrutinib derivative)	-
33707	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34586829	254522	10813	Bivalent ligand 584	MS67|bivalent_ligand_584	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	target	Standardized BVL Name: MS67 (VHL:VHL-1-Me --- WDR5:OICR-9429)	-
33709	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	38019706	254524	10814	Bivalent ligand 585	MS132/Compound 11|bivalent_ligand_585	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	target	Standardized BVL Name: MS132 (VHL:VHL-1 --- WDR5:precursor 2 (OICR-9429 derivative))	-
33711	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	38019706	254524	10815	Bivalent ligand 586	Compound 25|bivalent_ligand_586	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	target	Standardized BVL Name: Compound 25 (CRBN:-oxyacetamide bridged pomalidomide --- WDR5:OICR-9429)	-
33713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang W (2021)	33859747	254525	10816	Bivalent ligand 587	C004019|bivalent_ligand_587	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: C004019 (VHL:VH032 --- tau:triazole-based tau binder moiety)	-
33715	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK4:Palbociclib)	-
33717	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK6:Palbociclib)	-
33719	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sang R (2023)	37376788	254527	10818	Bivalent ligand 589	C-02|bivalent_ligand_589	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109346	3099	-	HK2	HKII|HXK2	9606	Homo sapiens	target	Standardized BVL Name: C-02 (CRBN:Thalidomide --- HK2:lonidamine)	-
33721	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Peyman M (2023)	37826940	254528	10819	Bivalent ligand 590	ALT-PG2|bivalent_ligand_590	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108367	2053	-	EPHX2	CEH|SEH	9606	Homo sapiens	target	Standardized BVL Name: ALT-PG2 (CRBN:Thalidomide --- sEH:t-TUCB)	-
33723	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Y (2023)	36947831	254529	10820	Bivalent ligand 591	compound 1a|bivalent_ligand_591	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108367	2053	-	EPHX2	CEH|SEH	9606	Homo sapiens	target	Standardized BVL Name: compound 1a (CRBN:Thalidomide --- sEH:t-TUCB)	-
33725	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	LegaardAndersson J (2023)	37807669	254535	10821	Bivalent ligand 600	Compound 3|bivalent_ligand_600	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113306	7468	RP11-262P20.3	WHSC1	MMSET|NSD2|REIIBP|TRX5|WHS	9606	Homo sapiens	target	Standardized BVL Name: compound 3 (VHL:VHL4 --- NSD2:DEL140 compound 1)	-
33727	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Pan P (2023)	37751283	254536	10822	Bivalent ligand 601	PPM-3|bivalent_ligand_601	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: PPM-3 (VHL:VH032 --- ERK5:XMD8-92)	-
33729	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10823	Bivalent ligand 602	22-SLF|bivalent_ligand_602	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: 22-SLF (FBXO22:22 --- FKBP12:SLF)	-
33731	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10824	Bivalent ligand 603	22a-SLF|bivalent_ligand_603	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: 22-SLF (FBXO22:22a --- FKBP12:SLF)	-
33733	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10825	Bivalent ligand 604	22-JQ1|bivalent_ligand_604	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 22-JQ1 (FBXO22:22 --- BRD4:JQ1)	-
33735	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10826	Bivalent ligand 605	22-TAE|bivalent_ligand_605	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: 22-TAE (FBXO22:22 --- ALK:TAE)	-
33737	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ko T (2023)	37712589	254591	10827	Bivalent ligand 606	CaMKIIa-PHOTAC|bivalent_ligand_606	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107265	815	-	CAMK2A	CAMKA	9606	Homo sapiens	target	Standardized BVL Name: CaMKII-PHOTAC (CRBN:lenalidomide --- CAMK2A:bosutinib)	-
33739	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Castellani B (2023)	37699425	254593	10828	Bivalent ligand 607	Compound 9|bivalent_ligand_607	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Compound 9 (VHL:MTX-23 CRL2VHL ligand derivative --- AR:AR DBD binding molecule)	-
33741	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Fan H (2023)	37683536	254595	10829	Bivalent ligand 608	precursor 1a|bivalent_ligand_608	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: precursor 1a (VHL:VHL Ligand with GSH-responsive capping group --- BRD4:JQ1)	-
33743	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu T (2023)	37672930	254597	10830	Bivalent ligand 609	CP-07|bivalent_ligand_609	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: CP-07 (CRBN:thalidomide --- CDK9:LWT-111)	-
33745	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ji W (2023)	37658265	254598	10831	Bivalent ligand 610	degrader 10e|bivalent_ligand_610	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111161	5134	RP1-191N21.2	PDCD2	RP8|ZMYND7	9606	Homo sapiens	target	Standardized BVL Name: degrader 10e (CRBN:thalidomide --- PDCD2:TEAD palmitoylation inhibitor)	-
33747	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Z (2023)	37647546	254601	10832	Bivalent ligand 611	ERD-3111|bivalent_ligand_611	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ERD-3111 (CRBN:TX-16 --- ESRA:lasofoxifene)	-
33749	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10833	Bivalent ligand 612	FC-14369|bivalent_ligand_612	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-14369 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33751	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10834	Bivalent ligand 613	FC-13182|bivalent_ligand_613	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-13182 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33753	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10835	Bivalent ligand 614	FC-13887|bivalent_ligand_614	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-13887 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33755	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10836	Bivalent ligand 615	FC-12988|bivalent_ligand_615	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-12988 (CRBN:lenalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33757	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10837	Bivalent ligand 616	FC-13818|bivalent_ligand_616	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-13818 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33759	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10838	Bivalent ligand 617	FC-13935|bivalent_ligand_617	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-13935 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33761	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10839	Bivalent ligand 618	FC-14228|bivalent_ligand_618	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-14228 (CRBN:thalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33763	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Emert-Sedlak LA (2024)	38508197	254603	10840	Bivalent ligand 619	FC-14367|bivalent_ligand_619	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	1205545	156110	HIV1gp9	nef	-	11676	Human Immunodeficiency Virus 1	target	Standardized BVL Name: FC-14367 (CRBN:lenalidomide --- Nef:hydroxypyrazole Nef-targeting moiety)	-
33765	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao C (2023)	37638390	254605	10841	Bivalent ligand 620	P7|bivalent_ligand_620	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: P7 (VHL:VHL-021 --- HDAC3:16 (BRD3308 derivative))	-
33767	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10842	Bivalent ligand 621	Comp-K|bivalent_ligand_621	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-K (VHL:VH032 --- CypA:2d (CypA-L1))	-
33769	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10843	Bivalent ligand 622	Comp-L|bivalent_ligand_622	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-L (VHL:VH032 --- CypA:2d (CypA-L1))	-
33771	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10844	Bivalent ligand 623	Comp-M|bivalent_ligand_623	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-M (VHL:VH032 --- CypA:3c (CypA-L2))	-
33773	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK4:palbociclib)	-
33775	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK6:palbociclib)	-
33777	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kumarasamy V (2023)	37626264	254608	10846	Bivalent ligand 625	FN-POM|bivalent_ligand_625	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: FN-POM (CRBN:pomalidomide --- CDK2:N-1501)	-
33779	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang Q (2023)	37619298	254609	10847	Bivalent ligand 626	X10g|bivalent_ligand_626	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109552	3320	-	HSP90AA1	EL52|HSP86|HSP89A|HSP90A|HSP90N|HSPC1|HSPCA|HSPCAL1|HSPCAL4|HSPN|Hsp89|Hsp90|LAP-2|LAP2	9606	Homo sapiens	target	Standardized BVL Name: X10g (CRBN:pomalidomide --- HSP90AA1:AT13387 analogue X1)	-
33781	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang L (2024)	38334978	254612	10848	Bivalent ligand 627	NR-V04|bivalent_ligand_627	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109407	3164	-	NR4A1	GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3	9606	Homo sapiens	target	Standardized BVL Name: NR-V04 (VHL:VHL-032 --- NR4A1:celastrol)	-
33783	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li C (2023)	37605297	254613	10849	Bivalent ligand 628	PIK5-12d|bivalent_ligand_628	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	128336	200576	-	PIKFYVE	CFD|FAB1|HEL37|PIP5K|PIP5K3|ZFYVE29	9606	Homo sapiens	target	Standardized BVL Name: PIK5-12d (VHL:VHL Ligand --- PIKfyve:apilimod)	-
33785	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hatcher JM (2023)	37591317	254614	10850	Bivalent ligand 629	JH-XII-03-02 (6)|bivalent_ligand_629	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	211674	66725	-	Lrrk2	4921513O20Rik|9330188B09Rik|AW561911|D630001M17Rik|Gm927|cI-46	10090	Mus musculus	target	Standardized BVL Name: JH-XII-03-02(6) (CRBN:pomalidomide --- LRRK2:MLi-2)	-
33787	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2023)	37572669	254616	10851	Bivalent ligand 630	YX968 (25)|bivalent_ligand_630	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: YX968 (25) (VHL:VHL-021 --- HDAC3:Compound 15)	-
33789	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2023)	37572669	254616	10851	Bivalent ligand 630	YX968 (25)|bivalent_ligand_630	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120968	55869	CDA07	HDAC8	CDLS5|HD8|HDACL1|MRXS6|RPD3|WTS	9606	Homo sapiens	target	Standardized BVL Name: YX968 (25) (VHL:VHL-021 --- HDAC8:Compound 15)	-
33791	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37572533	254628	10852	Bivalent ligand 631	E-3P-MDM2|bivalent_ligand_631	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: E-3P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33793	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37572533	254628	10853	Bivalent ligand 632	E-4P-MDM2|bivalent_ligand_632	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: E-4P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33795	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang B (2023)	37556600	254637	10854	Bivalent ligand 633	BWA-522 (28)|bivalent_ligand_633	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: BWA-522 (28) (CRBN:thalidomide --- AR:EPI-002)	-
33797	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li Y (2023)	37552639	254640	10855	Bivalent ligand 634	AD4|bivalent_ligand_634	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115114	9768	L5	KIAA0101	NS5ATP9|OEATC|OEATC-1|OEATC1|PAF|PAF15|p15(PAF)|p15/PAF|p15PAF	9606	Homo sapiens	target	Standardized BVL Name: AD4 (CRBN:pomalidomide --- PCLAF:SM1044)	-
33799	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10856	Bivalent ligand 635	KTX-335|bivalent_ligand_635	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	201398	17289	RP23-30M20.1	Mertk	Eyk|Mer|Nyk|nmf12	10090	Mus musculus	target	Standardized BVL Name: KTX-335 (CRBN:CRBN ligand (non IMiD) --- MERTK:MERTK ligand)	-
33801	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10857	Bivalent ligand 636	KTX-652|bivalent_ligand_636	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	201398	17289	RP23-30M20.1	Mertk	Eyk|Mer|Nyk|nmf12	10090	Mus musculus	target	Standardized BVL Name: KTX-652 (CRBN:CRBN ligand (non IMiD) --- MERTK:MERTK ligand)	-
33803	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10857	Bivalent ligand 636	KTX-652|bivalent_ligand_636	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	204922	26362	-	Axl	AI323647|Ark|Tyro7|Ufo	10090	Mus musculus	target	Standardized BVL Name: KTX-652 (CRBN:CRBN ligand (non IMiD) --- AXL:MERTK ligand)	-
33805	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10858	Bivalent ligand 637	KTX-978|bivalent_ligand_637	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	201398	17289	RP23-30M20.1	Mertk	Eyk|Mer|Nyk|nmf12	10090	Mus musculus	target	Standardized BVL Name: KTX-978 (CRBN:CRBN ligand (non IMiD) --- MERTK:MERTK ligand)	-
33807	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10858	Bivalent ligand 637	KTX-978|bivalent_ligand_637	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	204922	26362	-	Axl	AI323647|Ark|Tyro7|Ufo	10090	Mus musculus	target	Standardized BVL Name: KTX-978 (CRBN:CRBN ligand (non IMiD) --- AXL:MERTK ligand)	-
33809	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gadiyar V (2023)	37545504	254641	10858	Bivalent ligand 637	KTX-978|bivalent_ligand_637	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	204395	22174	RP23-356L21.1	Tyro3	AI323366|Brt|Dtk|Etk-2|Rse|Sky|TK19-2|Tif|etk2/tyro3	10090	Mus musculus	target	Standardized BVL Name: KTX-978 (CRBN:CRBN ligand (non IMiD) --- TYRO3:MERTK ligand)	-
33811	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Rathje OH (2023)	37535857	254770	10859	Bivalent ligand 638	Compound 36|bivalent_ligand_638	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	128244	197259	-	MLKL	hMLKL	9606	Homo sapiens	target	Standardized BVL Name: Compound 36 (CRBN:Lenalidomide --- MLKL:Ligand 1)	-
33813	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10860	Bivalent ligand 639	SMD-3040 (29)|bivalent_ligand_639	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: SMD-3040 (29) (VHL:VHL Ligand --- SMARCA2:compound 3)	-
33815	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10861	Bivalent ligand 640	Compound 15|bivalent_ligand_640	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: Compound 15 (VHL:VHL Ligand --- SMARCA2:compound 3)	-
33817	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10861	Bivalent ligand 640	Compound 15|bivalent_ligand_640	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: Compound 15 (VHL:VHL Ligand --- SMARCA4:compound 3)	-
33819	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cantley J (2022)	36357397	254785	10862	Bivalent ligand 641	A947|bivalent_ligand_641	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: A947 (VHL:VHL Ligand --- SMARCA2:SMARCA2/4/PBRM1 Ligand)	-
33821	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cantley J (2022)	36357397	254785	10862	Bivalent ligand 641	A947|bivalent_ligand_641	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: A947 (VHL:VHL Ligand --- SMARCA4:SMARCA2/4/PBRM1 Ligand)	-
33823	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kofink C (2022)	36216795	254788	10863	Bivalent ligand 642	ACBI2|bivalent_ligand_642	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: ACBI2 (VHL:VHL ligand VH101 --- SMARCA2:SMARCA2/4/PBRM1 binder compound 3)	-
33825	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ismail TM (2023)	37509135	254795	10864	Bivalent ligand 643	RGC-01-05-18|bivalent_ligand_643	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112183	6275	-	S100A4	18A2|42A|CAPL|FSP1|MTS1|P9KA|PEL98	9606	Homo sapiens	target	Standardized BVL Name: RGC-01-05-18 (CRBN:thalidomide --- S100A4:US-10113)	-
33827	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Huang J (2023)	37487306	254800	10865	Bivalent ligand 644	compound 15|bivalent_ligand_644	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 15 (CRBN:pomalidomide --- BTK:ibrutinib)	-
33829	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bockstiegel J (2023)	37481141	254804	10866	Bivalent ligand 645	A6|bivalent_ligand_645	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC6:pan-HDAC inhibitor SAHA)	-
33831	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ayinde OR (2023)	37465296	254805	10867	Bivalent ligand 646	Compound 14|bivalent_ligand_646	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: Compound 14 (CRBN:thalidomide --- CDK9:AT7519)	-
33833	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2023)	37449865	254807	10868	Bivalent ligand 647	WJ662|bivalent_ligand_647	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: WJ662 (VHL:VH 032 --- VHL:VH 032)	-
33835	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Valdivia A (2023)	37449845	254808	10869	Bivalent ligand 648	Compound 11|bivalent_ligand_648	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112910	7052	RP5-1054A22.2	TGM2	G-ALPHA-h|GNAH|HEL-S-45|TG2|TGC	9606	Homo sapiens	target	Standardized BVL Name: Compound 11 (VHL:VH032 --- TG2:MT4)	-
33837	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Valdivia A (2023)	37449845	254808	10870	Bivalent ligand 649	Compound 7|bivalent_ligand_649	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112910	7052	RP5-1054A22.2	TGM2	G-ALPHA-h|GNAH|HEL-S-45|TG2|TGC	9606	Homo sapiens	target	Standardized BVL Name: Compound 7 (VHL:VH032 --- TG2:MT4)	-
33839	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wurnig S (2023)	37448856	254811	10871	Bivalent ligand 650	3a|bivalent_ligand_650	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109552	3320	-	HSP90AA1	EL52|HSP86|HSP89A|HSP90A|HSP90N|HSPC1|HSPCA|HSPCAL1|HSPCAL4|HSPN|Hsp89|Hsp90|LAP-2|LAP2	9606	Homo sapiens	target	Standardized BVL Name: 3a (CRBN:pomalidomide --- HSP90AA1:geldanamycin)	-
33841	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wurnig S (2023)	37448856	254811	10871	Bivalent ligand 650	3a|bivalent_ligand_650	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109558	3326	RP1-302G2.1	HSP90AB1	D6S182|HSP84|HSP90B|HSPC2|HSPCB	9606	Homo sapiens	target	Standardized BVL Name: 3a (CRBN:pomalidomide --- HSP90AB1:geldanamycin)	-
33843	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li P (2023)	37425039	254812	10872	Bivalent ligand 651	D10|bivalent_ligand_651	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: D10 (CRBN:thalidomide --- c-MET:tepotinib)	-
33845	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li P (2023)	37425039	254812	10873	Bivalent ligand 652	D15|bivalent_ligand_652	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: D15 (CRBN:thalidomide --- c-MET:tepotinib)	-
33847	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wei Y (2023)	37418973	254814	10874	Bivalent ligand 653	compound 9q|bivalent_ligand_653	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 9q (CRBN:Lenalidomide --- GSPT1:CC-885 target ligand derivative)	-
33849	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bagka M (2023)	37393376	254824	10875	Bivalent ligand 654	HPP-9|bivalent_ligand_654	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: HPP-9 (CRBN:Hydroxythalidomide --- BRD2:HPI-1)	-
33851	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bagka M (2023)	37393376	254824	10875	Bivalent ligand 654	HPP-9|bivalent_ligand_654	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: HPP-9 (CRBN:Hydroxythalidomide --- BRD3:HPI-1)	-
33853	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bagka M (2023)	37393376	254824	10875	Bivalent ligand 654	HPP-9|bivalent_ligand_654	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: HPP-9 (CRBN:Hydroxythalidomide --- BRD4:HPI-1)	-
33855	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Qi M (2023)	37386884	254833	10876	Bivalent ligand 655	PROTAC I-d|bivalent_ligand_655	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	206135	50868	-	Keap1	INRF2|mKIAA0132	10090	Mus musculus	target	Standardized BVL Name: PROTAC I-d (CRBN:pomalidomide --- Keap1:CDDO)	-
33857	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2023)	37382562	254846	10877	Bivalent ligand 656	ARD-2051|bivalent_ligand_656	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-2051 (CRBN:thalidomide --- AR:AR ligand 15a methyl derivative)	-
33859	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang P (2023)	37369332	254853	10878	Bivalent ligand 657	compound C5|bivalent_ligand_657	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	target	Standardized BVL Name: compound C5 (VHL:VHL ligand 2 --- NAMPT:FK866)	-
33861	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Park SY (2023)	37348157	254854	10879	Bivalent ligand 658	SD2267|bivalent_ligand_658	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	target	Standardized BVL Name: SD2267 (CRBN:pomalidomide --- KEAP1:Compound 8)	-
33863	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ody BK (2023)	37625128	254777	10880	Bivalent ligand 659	HaloPROTAC-4b|bivalent_ligand_659	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-4b (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33865	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ody BK (2023)	37625128	254777	10881	Bivalent ligand 660	HaloPROTAC-5c|bivalent_ligand_660	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-5c (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33867	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ody BK (2023)	37625128	254777	10882	Bivalent ligand 661	HaloPROTAC-3|bivalent_ligand_661	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-3 (VHL:degradation moiety B --- EGFR:EGFP-HaloTag2)	-
33869	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10883	Bivalent ligand 662	11|bivalent_ligand_662	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: 11 (CRBN:pomalidomide --- AR:Enzalutamide)	-
33871	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10884	Bivalent ligand 663	13|bivalent_ligand_663	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: 13 (CRBN:pomalidomide --- AR:Androgen receptor antagonist 1)	-
33873	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10885	Bivalent ligand 664	14|bivalent_ligand_664	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 14 (CRBN:pomalidomide --- BRD4:JQ1)	-
33875	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10886	Bivalent ligand 665	15|bivalent_ligand_665	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 15 (CRBN:pomalidomide --- BRD4:JQ1)	-
33877	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10887	Bivalent ligand 666	16|bivalent_ligand_666	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 16 (CRBN:pomalidomide --- BRD4:JQ1)	-
33879	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10888	Bivalent ligand 667	18|bivalent_ligand_667	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	target	Standardized BVL Name: 18 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33881	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10889	Bivalent ligand 668	19|bivalent_ligand_668	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	target	Standardized BVL Name: 19 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33883	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620218	256641	10890	Bivalent ligand 669	21|bivalent_ligand_669	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108405	2101	-	ESRRA	ERR1|ERRa|ERRalpha|ESRL1|NR3B1	9606	Homo sapiens	target	Standardized BVL Name: 21 (CRBN:pomalidomide --- ERRalpha:E3 ligase Ligand 5)	-
33885	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10891	Bivalent ligand 670	I-215|bivalent_ligand_670	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-215 (CRBN:pomalidomide--- IRAK4:IRAK4 binding moiety 1)	-
33887	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10892	Bivalent ligand 671	I-219|bivalent_ligand_671	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-219 (CRBN:pomalidomide--- IRAK4:IRAK4 binding moiety 1)	-
33889	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10893	Bivalent ligand 672	I-222|bivalent_ligand_672	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-222 (CRBN:pomalidomide--- IRAK4:IRAK4 binding moiety 2)	-
33891	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10894	Bivalent ligand 673	I-228|bivalent_ligand_673	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-228 (CRBN:thalidomide--- IRAK4:IRAK4 binding moiety 3)	-
33893	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10895	Bivalent ligand 674	I-265|bivalent_ligand_674	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-265 (CRBN:Compound I-1--- IRAK4:IRAK4 binding moiety 4)	-
33895	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10896	Bivalent ligand 675	I-283|bivalent_ligand_675	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-283 (CRBN:pomalidomide--- IRAK4:IRAK4 binding moiety 5)	-
33897	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10897	Bivalent ligand 676	I-305|bivalent_ligand_676	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-305 (CRBN:pomalidomide--- IRAK4:IRAK4 binding moiety 1)	-
33899	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10898	Bivalent ligand 677	I-308|bivalent_ligand_677	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-308 (CRBN:thalidomide--- IRAK4:IRAK4 binding moiety 3)	-
33901	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10899	Bivalent ligand 678	I-309|bivalent_ligand_678	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-309 (CRBN:thalidomide--- IRAK4:IRAK4 binding moiety 6)	-
33903	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2019)	31620217	256642	10900	Bivalent ligand 679	I-313|bivalent_ligand_679	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: I-313 (CRBN:thalidomide--- IRAK4:IRAK4 binding moiety 3)	-
33905	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zheng M (2021)	33706076	256643	10901	Bivalent ligand 680	SP4|bivalent_ligand_680	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: SP4 (CRBN:pomalidomide --- PTPN11:SHP099)	-
33907	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li Z (2020)	33088687	256644	10902	Bivalent ligand 681	9c|bivalent_ligand_681	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106658	148	-	ADRA1A	ADRA1C|ADRA1L1|ALPHA1AAR	9606	Homo sapiens	target	Standardized BVL Name: 9c (CRBN:pomalidomide --- ADRA1A:prazosin)	-
33909	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sinatra L (2020)	32780485	256645	10903	Bivalent ligand 682	HDAC PROTAC 4|bivalent_ligand_682	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: HDAC PROTAC 4 (CRBN:thalidomide-based ligand ---HDAC1:HAIR D)	-
33911	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sinatra L (2020)	32780485	256645	10903	Bivalent ligand 682	HDAC PROTAC 4|bivalent_ligand_682	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: HDAC PROTAC 4 (CRBN:thalidomide-based ligand ---HDAC1:HAIR D)	-
33913	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sinatra L (2022)	36473103	256646	10904	Bivalent ligand 683	A6|bivalent_ligand_683	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC6:vorinostat-like HDAC ligand)	-
33915	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sinatra L (2022)	36473103	256646	10904	Bivalent ligand 683	A6|bivalent_ligand_683	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC1:vorinostat-like HDAC ligand)	-
33917	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sinatra L (2022)	36473103	256646	10905	Bivalent ligand 684	B4|bivalent_ligand_684	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	target	Standardized BVL Name: B4 (CRBN:thalidomide --- HDAC6:benzimidazole-based HDAC6 ligand)	-
33919	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu F (2022)	35652200	256647	10906	Bivalent ligand 685	dAurA383|bivalent_ligand_685	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAurA383 (CRBN:thalidomide --- AURKA:MLN8237)	-
33921	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu F (2022)	35652200	256647	10907	Bivalent ligand 686	dAurA425|bivalent_ligand_686	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAurA425 (VHL:VH032 --- AURKA:MLN8237)	-
33923	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Liu F (2022)	35652200	256647	10908	Bivalent ligand 687	dAurA450|bivalent_ligand_687	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAurA450 (cIAP1:cIAP1 ligand --- AURKA:MLN8237)	-
33925	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang L (2021)	33664520	256648	10909	Bivalent ligand 688	CPS2|bivalent_ligand_688	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: CPS2 (CRBN:pomalidomide --- CDK2:J2)	-
33927	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jin J (2022)	36509291	256649	10910	Bivalent ligand 689	TSM-1|bivalent_ligand_689	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	target	Standardized BVL Name: TSM-1 (CRBN:lenalidomide --- STAT3:Toosendanin)	-
33929	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	36508995	256650	10911	Bivalent ligand 690	SV|bivalent_ligand_690	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111185	5159	-	PDGFRB	CD140B|IBGC4|IMF1|JTK12|PDGFR|PDGFR-1|PDGFR1	9606	Homo sapiens	target	Standardized BVL Name: SV (VHL:VH032 --- PDGFRB:sorafenib)	-
33931	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	36508995	256650	10912	Bivalent ligand 691	SL|bivalent_ligand_691	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111185	5159	-	PDGFRB	CD140B|IBGC4|IMF1|JTK12|PDGFR|PDGFR-1|PDGFR1	9606	Homo sapiens	target	Standardized BVL Name: SL (CRBN:lenalidomide --- PDGFRB:sorafenib)	-
33933	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	36508995	256650	10913	Bivalent ligand 692	SF|bivalent_ligand_692	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111185	5159	-	PDGFRB	CD140B|IBGC4|IMF1|JTK12|PDGFR|PDGFR-1|PDGFR1	9606	Homo sapiens	target	Standardized BVL Name: SF (CRBN:4-fluoro-thalidomide --- PDGFRB:sorafenib)	-
33935	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen H (2023)	36473314	256651	10914	Bivalent ligand 693	PROTAC 14|bivalent_ligand_693	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 14 (CRBN:thalidomide --- KEAP1:inhibitor 2)	-
33937	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen J (2022)	35395439	256652	10915	Bivalent ligand 694	7f|bivalent_ligand_694	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 7f (CRBN:pomalidomide --- BRD4:ABBV-744)	-
33939	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen J (2022)	35395439	256652	10916	Bivalent ligand 695	13d|bivalent_ligand_695	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 13d (CRBN:pomalidomide ---BRD4:ABBV-744)	-
33941	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Z (2021)	34018657	255460	10917	Bivalent ligand 696	MD13|bivalent_ligand_696	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	target	Standardized BVL Name: MD13 (CRBN:pomalidomide --- MIF:Compound 3 (MIF tautomerase inhibitor))	-
33943	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Du G (2021)	33915015	255461	10918	Bivalent ligand 697	DGY-09-192|bivalent_ligand_697	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108551	2260	-	FGFR1	BFGFR|CD331|CEK|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1	9606	Homo sapiens	target	Standardized BVL Name: DGY-09-192 (VHL:VHL ligand --- FGFR1:BGJ398)	-
33945	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Du G (2021)	33915015	255461	10918	Bivalent ligand 697	DGY-09-192|bivalent_ligand_697	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108554	2263	-	FGFR2	BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25	9606	Homo sapiens	target	Standardized BVL Name: DGY-09-192 (VHL:VHL ligand --- FGFR2:BGJ398)	-
33947	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou H (2021)	34141084	255462	10919	Bivalent ligand 698	SD-91|bivalent_ligand_698	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	target	Standardized BVL Name: SD-91 (CRBN:lenalidomide --- STAT3:SI-191)	-
33949	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang H (2022)	35178183	255463	10920	Bivalent ligand 699	Compound 6h|bivalent_ligand_699	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: Compound 6h (VHL:VHL ligand --- EGFR Del19/T790M/C797S:brigatinib analog 3)	-
33951	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen S (2023)	37119666	255464	10921	Bivalent ligand 700	compound 3e|bivalent_ligand_700	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 3e (CRBN:Lenalidomide-6-F --- BTK:ARQ-531 derivative)	-
33953	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Y (2021)	34509879	255466	10922	Bivalent ligand 701	compound 4f|bivalent_ligand_701	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 4f (CRBN:pomalidomide --- BTK:warhead A (ARQ531 derivative Compound 4))	-
33955	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Y (2021)	34509879	255466	10923	Bivalent ligand 702	compound 4g|bivalent_ligand_702	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 4g (CRBN:pomalidomide --- BTK:warhead A (ARQ531 derivative Compound 4))	-
33957	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Y (2021)	34509879	255466	10924	Bivalent ligand 703	compound 6c|bivalent_ligand_703	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 6c (CRBN:pomalidomide --- BTK:warhead B (ARQ531 derivative Compound 6))	-
33959	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Y (2021)	34509879	255466	10925	Bivalent ligand 704	compound 6d|bivalent_ligand_704	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 6d (CRBN:pomalidomide --- BTK:warhead B (ARQ531 derivative Compound 6))	-
33961	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Y (2021)	34509879	255466	10926	Bivalent ligand 705	compound 6e|bivalent_ligand_705	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: compound 6e (CRBN:pomalidomide --- BTK:warhead B (ARQ531 derivative Compound 6))	-
33963	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang B (2021)	33862513	232662	10928	Bivalent ligand 707	WB214|bivalent_ligand_707	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: WB214 (CRBN:lenalidomide --- MDM2:MDM2 Ugi ligand 1)	-
33965	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang B (2021)	33862513	232662	10928	Bivalent ligand 707	WB214|bivalent_ligand_707	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: WB214 (CRBN:lenalidomide --- GSPT1:MDM2 Ugi ligand 1)	-
33967	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang B (2021)	33862513	232662	10929	Bivalent ligand 708	compound 36|bivalent_ligand_708	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109190	2935	-	GSPT1	551G9.2|ETF3A|GST1|eRF3a	9606	Homo sapiens	target	Standardized BVL Name: compound 36 (CRBN:lenalidomide --- GSPT1:MDM2 Ugi ligand 1 derivative)	-
33969	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Shi W (2022)	35279611	255470	10930	Bivalent ligand 709	compound 20|bivalent_ligand_709	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (CRBN:lenalidomide --- AXL:R428 derivative)	-
33971	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Shi W (2022)	35279611	255470	10931	Bivalent ligand 710	compound 22|bivalent_ligand_710	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	target	Standardized BVL Name: compound 22 (CRBN:lenalidomide --- AXL:R428 derivative)	-
33973	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Niu T (2022)	34864331	255472	10932	Bivalent ligand 711	PP-C8|bivalent_ligand_711	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: PP-C8 (CRBN:pomalidomide --- CDK12:compound 3 (CDK12 inhibitor 1 derivative))	-
33975	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2021)	33753926	255473	10933	Bivalent ligand 712	BSJ-4-116|bivalent_ligand_712	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: BSJ-4-116 (CRBN:thalidomide --- CDK12:TL13-87 derivative)	-
33977	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jiang B (2021)	33753926	255473	10934	Bivalent ligand 713	BSJ-4-23|bivalent_ligand_713	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: BSJ-4-23 (CRBN:thalidomide --- CDK12:THZ531 fragment 5)	-
33979	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Dieter SM (2021)	34289372	255474	10935	Bivalent ligand 714	NCT02|bivalent_ligand_714	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: NCT02 (DDB1:NCT02 --- CCNK:NCT02)	-
33981	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hati S (2021)	34560429	255476	10936	Bivalent ligand 715	PROTAC-8|bivalent_ligand_715	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-8 (VHL:VH032 --- CDK2:AZD5438)	-
33983	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10937	Bivalent ligand 716	Halo-PROTAC 3|bivalent_ligand_716	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117422	25921	-	ZDHHC5	DHHC5|ZNF375	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 3 (VHL:VH032 --- zDHHC5:Halo-zDHHC5)	-
33985	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10938	Bivalent ligand 717	Halo-PROTAC 1|bivalent_ligand_717	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117422	25921	-	ZDHHC5	DHHC5|ZNF375	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 1 (VHL:fluorocyclopropane-containing VHL-targeting ligand --- zDHHC5:Halo-zDHHC5)	-
33987	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10939	Bivalent ligand 718	Halo-PROTAC 2|bivalent_ligand_718	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	128991	253832	-	ZDHHC20	4933421L13Rik|DHHC-20	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 2 (CRBN:pomalidomide --- zDHHC20:Halo-zDHHC20)	-
33989	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10937	Bivalent ligand 716	Halo-PROTAC 3|bivalent_ligand_716	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	128991	253832	-	ZDHHC20	4933421L13Rik|DHHC-20	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 3 (VHL:VH032 --- zDHHC20:Halo-zDHHC20)	-
33991	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10938	Bivalent ligand 717	Halo-PROTAC 1|bivalent_ligand_717	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	128991	253832	-	ZDHHC20	4933421L13Rik|DHHC-20	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 1 (VHL:fluorocyclopropane-containing VHL-targeting ligand --- zDHHC20:Halo-zDHHC20)	-
33997	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zheng X (2024)	39151120	256654	10941	Bivalent ligand 720	KT-474|bivalent_ligand_720	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: KT-474 (CRBN: (3S)-3-(3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidine-2,6-dione --- IRAK4:compound 4)	-
33999	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li N (2025)	40045307	256655	10942	Bivalent ligand 721	KT-333|bivalent_ligand_721	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	target	Standardized BVL Name: KT-333 (VHL:VHL ligand --- STAT3:undisclosed)	-
34001	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Salvaris RT (2025)	39941922	256656	10943	Bivalent ligand 722	NX-5948 (BTK-IN-24)|bivalent_ligand_722	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: NX-5948 (CRBN:undisclosed --- BTK:undisclosed)	-
34003	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Salvaris RT (2025)	39941922	256656	10944	Bivalent ligand 723	NX-2127|bivalent_ligand_723	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: NX-2127 (CRBN:Thalidomide 5-fluoride --- BTK:BTK ligand 10)	-
34027	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10954	Bivalent ligand 733	PS-RC-1|bivalent_ligand_733	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: PS-RC-1 (CRBN:pomalidomide ---IKZF1:pomalidomide)	-
34029	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10954	Bivalent ligand 733	PS-RC-1|bivalent_ligand_733	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: PS-RC-1 (CRBN:pomalidomide ---IKZF3:pomalidomide)	-
34031	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10955	Bivalent ligand 734	PS-1|bivalent_ligand_734	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: PS-1 (CRBN:pomalidomide ---IKZF1:pomalidomide)	-
34033	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10955	Bivalent ligand 734	PS-1|bivalent_ligand_734	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: PS-1 (CRBN:pomalidomide ---IKZF3:pomalidomide)	-
34035	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10956	Bivalent ligand 735	PS-2|bivalent_ligand_735	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: PS-2 (CRBN:pomalidomide ---IKZF1:pomalidomide)	-
34037	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10956	Bivalent ligand 735	PS-2|bivalent_ligand_735	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: PS-2 (CRBN:pomalidomide ---IKZF3:pomalidomide)	-
34039	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	36712232	256662	10956	Bivalent ligand 735	PS-2|bivalent_ligand_735	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: PS-2 (CRBN:pomalidomide ---BTK:poseltinib)	-
34041	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10957	Bivalent ligand 736	PHOTAC-I-3|bivalent_ligand_736	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide ---BRD3:JQ1)	-
34043	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10957	Bivalent ligand 736	PHOTAC-I-3|bivalent_ligand_736	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
34045	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10957	Bivalent ligand 736	PHOTAC-I-3|bivalent_ligand_736	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD2:JQ1)	-
34047	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10958	Bivalent ligand 737	PHOTAC-I-10|bivalent_ligand_737	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-I-10 (CRBN:thalidomide --- BRD4:JQ1)	-
34049	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10959	Bivalent ligand 738	PHOTAC-II-5|bivalent_ligand_738	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-II-5 (CRBN:glutarimide --- FKBP12:SLF)	-
34051	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Reynders M (2021)	34432252	256663	10960	Bivalent ligand 739	PHOTAC-II-6|bivalent_ligand_739	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: PHOTAC-II-6 (CRBN:glutarimide --- FKBP12:SLF)	-
34053	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10961	Bivalent ligand 740	MS928|bivalent_ligand_740	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS928 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34055	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10961	Bivalent ligand 740	MS928|bivalent_ligand_740	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS928 (VHL:VHL-1 --- MAP2K2:PD0325901)	-
34057	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10962	Bivalent ligand 741	MS934|bivalent_ligand_741	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS934 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34059	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10962	Bivalent ligand 741	MS934|bivalent_ligand_741	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS934 (VHL:VHL-1 --- MAP2K2:PD0325901)	-
34061	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10963	Bivalent ligand 742	MS910|bivalent_ligand_742	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS910 (CRBN:pomalidomide --- MAP2K1:PD0325901)	-
34063	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10963	Bivalent ligand 742	MS910|bivalent_ligand_742	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS910 (CRBN:pomalidomide --- MAP2K2:PD0325901)	-
34065	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- EZH2:EPZ6438)	-
34067	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- EED:EPZ6438)	-
34069	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- SUZ12:EPZ6438)	-
34071	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111863	5928	-	RBBP4	NURF55|RBAP48|lin-53	9606	Homo sapiens	target	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- RBBP4:EPZ6438)	-
34073	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10965	Bivalent ligand 744	compound 8|bivalent_ligand_744	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 8 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34075	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10966	Bivalent ligand 745	compound 9|bivalent_ligand_745	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34077	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10967	Bivalent ligand 746	compound 12|bivalent_ligand_746	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 12 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34079	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10968	Bivalent ligand 747	compound 13|bivalent_ligand_747	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 13 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34081	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hong JY (2020)	33214845	256667	10969	Bivalent ligand 748	TM-P2-Thal|bivalent_ligand_748	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: TM-P2-Thal (CRBN:thalidomide --- SIRT2: TM)	-
34083	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hong JY (2020)	33214845	256667	10970	Bivalent ligand 749	TM-P4-Thal|bivalent_ligand_749	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: TM-P4-Thal (CRBN:thalidomide --- SIRT2: TM)	-
34085	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2021)	33603969	256668	10971	Bivalent ligand 750	PROTAC(H-PGDS)-1|bivalent_ligand_750	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118128	27306	-	HPGDS	GSTS|GSTS1-1|PGD2|PGDS	9606	Homo sapiens	target	Standardized BVL Name: PROTAC(H-PGDS)-1 (CRBN:pomalidomide --- HPGDS:TFC-007)	-
34087	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EED:EED226)	-
34089	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EZH2:EED226)	-
34091	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---SUZ12:EED226)	-
34093	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EED:EED226)	-
34095	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EZH2:EED226)	-
34097	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---SUZ12:EED226)	-
34099	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10974	Bivalent ligand 753	UNC7698|bivalent_ligand_753	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7698 (VHL:VH032-amine ---EED:EED226)	-
34101	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun X (2019)	30729032	256670	10975	Bivalent ligand 754	RC32|bivalent_ligand_754	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: RC32 (CRBN:pomalidomide --- FKBP1A:rapamycin)	-
34103	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun X (2019)	30729032	256670	10975	Bivalent ligand 754	RC32|bivalent_ligand_754	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108571	2281	-	FKBP1B	FKBP12.6|FKBP1L|OTK4|PKBP1L|PPIase	9606	Homo sapiens	target	Standardized BVL Name: RC32 (CRBN:pomalidomide --- FKBP1B:rapamycin)	-
34105	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun X (2019)	30729032	256670	10975	Bivalent ligand 754	RC32|bivalent_ligand_754	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199682	14225	RP23-419G21.5	Fkbp1a	FKBP12|Fkbp|Fkbp1	10090	Mus musculus	target	Standardized BVL Name: RC32 (CRBN:pomalidomide --- Fkbp1a:rapamycin)	-
34107	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun X (2019)	30729032	256670	10975	Bivalent ligand 754	RC32|bivalent_ligand_754	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	247668	25639	-	Fkbp1a	FKBP12|Fkbp2	10116	Rattus norvegicus	target	Standardized BVL Name: RC32 (CRBN:pomalidomide --- Fkbp1a:rapamycin)	-
34109	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kim SA (2019)	30684871	220042	10976	Bivalent ligand 755	TD-106|bivalent_ligand_755	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	115604	10320	tcag7.1178	IKZF1	Hs.54452|IK1|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1	9606	Homo sapiens	target	Standardized BVL Name: TD-106 (CRBN:TD-106 --- IKZF1:TD-106)	-
34111	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kim SA (2019)	30684871	220042	10976	Bivalent ligand 755	TD-106|bivalent_ligand_755	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	116484	22806	RP11-94L15.2	IKZF3	AIO|AIOLOS|ZNFN1A3	9606	Homo sapiens	target	Standardized BVL Name: TD-106 (CRBN:TD-106 --- IKZF3:TD-106)	-
34113	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kim SA (2019)	30684871	220042	10977	Bivalent ligand 756	TD-428|bivalent_ligand_756	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: TD-428 (CRBN:TD-106 --- BRD4:JQ1)	-
34115	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	degradation	recruited e3 ligase	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- NEK9:YHJ1039)	-
34117	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	degradation	recruited e3 ligase	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- FAK:YHJ1039)	-
34119	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	degradation	recruited e3 ligase	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK4:YHJ1039)	-
34121	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	degradation	recruited e3 ligase	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK6:YHJ1039)	-
34123	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	degradation	recruited e3 ligase	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- WEE1:YHJ1039)	-
34125	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Wen T (2023)	37298935	256429	10979	Bivalent ligand 758	Compound 5|bivalent_ligand_758	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: Compound 5 (cIAP1 :bestatin --- SNCA:sery384)	-
34127	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Yi J (2023)	37291217	253028	10980	Bivalent ligand 759	PU7-1|bivalent_ligand_759	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	target	Standardized BVL Name: PU7-1 (CRBN:lenalidomaide --- USP7:XL-177A)	-
34129	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2023)	37279162	256430	10981	Bivalent ligand 760	SP27|bivalent_ligand_760	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: SP27 (CRBN:thalidomide --- PLK4:CZS-035)	-
34131	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK4:Palbociclib)	-
34133	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	degradation	recruited e3 ligase	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK6:Palbociclib)	-
34135	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Tong Y (2023)	37267712	256432	10983	Bivalent ligand 762	Compound 2b|bivalent_ligand_762	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: Compound 2b (CRBN:pomalidomide --- SNCA:sery308)	-
34137	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zahid H (2023)	37260298	256433	10984	Bivalent ligand 763	Compound 8|bivalent_ligand_763	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108481	2186	-	BPTF	FAC1|FALZ|NURF301	9606	Homo sapiens	target	Standardized BVL Name: Compound 8 (CRBN:pomalidomide --- BPTF:TP-238)	-
34139	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zahid H (2023)	37260298	256433	10984	Bivalent ligand 763	Compound 8|bivalent_ligand_763	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118176	27443	-	CECR2	-	9606	Homo sapiens	target	Standardized BVL Name: Compound 8 (CRBN:pomalidomide --- CECR2:TP-238)	-
34141	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zahid H (2023)	37260298	256433	10985	Bivalent ligand 764	Compound 9|bivalent_ligand_764	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108481	2186	-	BPTF	FAC1|FALZ|NURF301	9606	Homo sapiens	target	Standardized BVL Name: Compound 9 (CRBN:pomalidomide --- BPTF:TP-238)	-
34143	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cai M (2023)	37257255	256438	10986	Bivalent ligand 765	GDC-22|bivalent_ligand_765	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: GDC-22 (VHL:VHL Ligand --- GPX4:ML162-1)	-
34145	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ma L (2023)	37220310	256439	10987	Bivalent ligand 766	LC-MB12|bivalent_ligand_766	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108554	2263	-	FGFR2	BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25	9606	Homo sapiens	target	Standardized BVL Name: LC-MB12 (CRBN:thalidomide --- FGFR2 :infigratinib)	-
34147	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Guardigni M (2023)	37218653	256440	10988	Bivalent ligand 767	Compound 1|bivalent_ligand_767	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: Compound 1 (CRBN:pomalidomide --- GSK3B:SB-216763)	-
34149	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10989	Bivalent ligand 768	SIAIS352008|bivalent_ligand_768	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SIAIS352008 (CRBN:lenalidomide --- AAK1:brigatinib)	-
34151	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10989	Bivalent ligand 768	SIAIS352008|bivalent_ligand_768	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SIAIS352008 (CRBN:lenalidomide --- GAK:brigatinib)	-
34153	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10989	Bivalent ligand 768	SIAIS352008|bivalent_ligand_768	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SIAIS352008 (CRBN:lenalidomide --- FER:brigatinib)	-
34155	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10990	Bivalent ligand 769	SIAIS262039|bivalent_ligand_769	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: SIAIS262039 (CRBN:lenalidomide --- AAK1:brigatinib)	-
34157	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10990	Bivalent ligand 769	SIAIS262039|bivalent_ligand_769	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: SIAIS262039 (CRBN:lenalidomide --- GAK:brigatinib)	-
34159	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang Y (2023)	37196766	256442	10990	Bivalent ligand 769	SIAIS262039|bivalent_ligand_769	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: SIAIS262039 (CRBN:lenalidomide --- FER:brigatinib)	-
34161	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Li YQ (2023)	37195170	256443	10991	Bivalent ligand 770	PTD10|bivalent_ligand_770	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: PTD10 (CRBN:pomalidomide --- BTK:GDC-0853)	-
34163	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10992	Bivalent ligand 771	UNC9036|bivalent_ligand_771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC9036 (VHL:VH032 --- STING:diABZI compound 3)	-
34165	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10993	Bivalent ligand 772	UNC8899|bivalent_ligand_772	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC8899 (VHL:VH032 --- STING:diABZI compound 3)	-
34167	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10994	Bivalent ligand 773	UNC8900|bivalent_ligand_773	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC8900 (VHL:VH032 --- STING:diABZI compound 3)	-
34169	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Y (2023)	37182514	256445	10995	Bivalent ligand 774	PF|bivalent_ligand_774	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	203183	20371	RP23-54C14.1	Foxp3	JM2|scurfin|sf	10090	Mus musculus	target	Standardized BVL Name: PF (CRBN:pomalidomide --- FoxP3:P60 (FoxP3 binding peptide))	-
34171	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang Y (2023)	37182514	256445	10995	Bivalent ligand 774	PF|bivalent_ligand_774	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119170	50943	JM2	FOXP3	AIID|DIETER|IPEX|PIDX|XPID	9606	Homo sapiens	target	Standardized BVL Name: PF (CRBN:pomalidomide --- FoxP3:P60 (FoxP3 binding peptide))	-
34173	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Cui J (2023)	37175323	256446	10996	Bivalent ligand 775	XR-4|bivalent_ligand_775	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: XR-4 (MDM2:Compound 2 (spiroindolinone pyrrolidinecarboxamide Nutlin-3 derivative) --- MDM2:Compound 2 (spiroindolinone pyrrolidinecarboxamide Nutlin-3 derivative))	-
34175	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37163809	256447	10997	Bivalent ligand 776	PROTAC 8a|bivalent_ligand_776	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 8a (VHL:VHL ligand --- ESR1:OBHSA)	-
34177	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	10998	Bivalent ligand 777	ZD12|bivalent_ligand_777	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD12 (VHL:VHL ligand --- ESR1:OBHSA)	-
34179	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	10999	Bivalent ligand 778	ZD11|bivalent_ligand_778	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD11 (VHL:VHL ligand --- ESR1:OBHSA)	-
34181	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	11000	Bivalent ligand 779	ZD8|bivalent_ligand_779	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD8 (VHL:VHL ligand --- ESR1:OBHSA)	-
34183	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	11001	Bivalent ligand 780	ZD2|bivalent_ligand_780	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD2 (VHL:VHL ligand --- ESR1:OBHSA)	-
34185	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Gong L (2023)	37105002	256450	11002	Bivalent ligand 781	AP-1|bivalent_ligand_781	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: AP-1 (CRBN:thalidomide --- ALK:A1)	-
34187	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Tseng YL (2023)	37101169	256451	11003	Bivalent ligand 782	PROTAC 2/JMF4560|bivalent_ligand_782	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117003	23435	RP4-635E18.2	TARDBP	ALS10|TDP-43	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2/JMF4560 (CRBN:pomalidomide --- TDP43:BTA)	-
34189	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zheng C (2023)	37098297	256452	11004	Bivalent ligand 783	R17|bivalent_ligand_783	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: R17 (CRBN:lenalidomide --- GPX4:RSL3 analogue)	-
34191	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zheng C (2023)	37098297	256452	11005	Bivalent ligand 784	NC-R17|bivalent_ligand_784	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: NC-R17 (CRBN:lenalidomide --- GPX4:RSL3 analogue)	-
34193	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2023)	37094179	256453	11006	Bivalent ligand 785	DeFer-2|bivalent_ligand_785	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199759	14325	-	Ftl1	Ftl|Ftl-1|L-ferritin	10090	Mus musculus	target	Standardized BVL Name: DeFer-2 (VHL:VH032 --- FTL:oleic acid)	-
34195	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2023)	37094179	256453	11006	Bivalent ligand 785	DeFer-2|bivalent_ligand_785	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199755	14319	-	Fth1	FHC|Fth|HFt|MFH	10090	Mus musculus	target	Standardized BVL Name: DeFer-2 (VHL:VH032 --- FTH1:oleic acid)	-
34197	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wang H (2023)	37087895	256454	11007	Bivalent ligand 786	DC-2|bivalent_ligand_786	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: DC-2 (CRBN:pomalidomide --- GPX4:ML210)	-
34199	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Tokarski RJ (2023)	37071962	256455	11008	Bivalent ligand 787	Compound 15e|bivalent_ligand_787	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: Compound 15e (CRBN:thalidomide --- CDK9:AT7519)	-
34201	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Tokarski RJ (2023)	37071962	256455	11009	Bivalent ligand 788	Compound 16|bivalent_ligand_788	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: Compound 16 (CRBN:thalidomide --- CDK9:AT7519)	-
34203	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sharma C (2023)	37063743	256456	11010	Bivalent ligand 789	PRO-SIRT2|bivalent_ligand_789	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116593	22933	-	SIRT2	SIR2|SIR2L|SIR2L2	9606	Homo sapiens	target	Standardized BVL Name: PRO-SIRT2 (CRBN:thalidomide --- SIRT2:Probe 3A)	-
34205	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Wang W (2023)	37002536	256462	11011	Bivalent ligand 790	Compound 13|bivalent_ligand_790	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	201282	17133	-	Maff	-	10090	Mus musculus	target	Standardized BVL Name: Compound 13 (cIAP1:bestatin --- MAFF:lathyrol)	-
34207	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Wu Y (2022)	36386476	256471	11012	Bivalent ligand 791	ZCY-PROTAC|bivalent_ligand_791	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117264	23764	CTA-447C4.1	MAFF	U-MAF|hMafF	9606	Homo sapiens	target	Standardized BVL Name: ZCY-PROTAC (CRBN:thalidomide --- MAFF:lathyrol)	-
34209	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- cIAP1:CST530)	-
34211	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- cIAP2:CST530)	-
34213	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- XIAP:CST530)	-
34215	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11014	Bivalent ligand 793	hetero-PROTAC 25|bivalent_ligand_793	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 25 (CRBN:thalidomide --- cIAP1:CST530)	-
34217	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11014	Bivalent ligand 793	hetero-PROTAC 25|bivalent_ligand_793	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 25 (CRBN:thalidomide --- cIAP2:CST530)	-
34219	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11014	Bivalent ligand 793	hetero-PROTAC 25|bivalent_ligand_793	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 25 (CRBN:thalidomide --- XIAP:CST530)	-
34221	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11015	Bivalent ligand 794	hetero-PROTAC 27|bivalent_ligand_794	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 27 (CRBN:thalidomide --- XIAP:CST530)	-
34223	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dong J (2023)	36973833	256473	11016	Bivalent ligand 795	DU-14|bivalent_ligand_795	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111736	5770	-	PTPN1	PTP1B	9606	Homo sapiens	target	Standardized BVL Name: DU-14 (VHL:(S,R,S)-AHPC-Me --- PTP1B:DI-03)	-
34225	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dong J (2023)	36973833	256473	11016	Bivalent ligand 795	DU-14|bivalent_ligand_795	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111737	5771	-	PTPN2	PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP	9606	Homo sapiens	target	Standardized BVL Name: DU-14 (VHL:(S,R,S)-AHPC-Me --- TC-PTP:DI-03)	-
34227	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Son SH (2023)	36968534	256474	11017	Bivalent ligand 796	PRZ-18002|bivalent_ligand_796	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: PRZ-18002 (CRBN:pomalidomide --- MAPK14:p-p38 ligand)	-
34229	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou D (2023)	36959108	256475	11018	Bivalent ligand 797	Compound 28|bivalent_ligand_797	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: Compound 28 (CRBN:pomalidomide --- ITK:GNE-9822)	-
34231	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Sohbati H (2022)	36942064	256498	11019	Bivalent ligand 798	compound 2|bivalent_ligand_798	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109827	3614	-	IMPDH1	IMPD|IMPD1|LCA11|RP10|sWSS2608	9606	Homo sapiens	target	Standardized BVL Name: compound 2 (CRBN:pomalidomide --- IMPDH:mycophenolic acid)	-
34233	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu L (2023)	36924654	256499	11020	Bivalent ligand 799	PD-4|bivalent_ligand_799	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: PD-4 (CRBN:pomalidomide --- GPX4:ML-162)	-
34235	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu L (2023)	36924654	256499	11021	Bivalent ligand 819	PD-P2|bivalent_ligand_819	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: PD-P2 (CRBN:pomalidomide --- GPX4:ML-162)	-
34237	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Chang M (2022)	36910255	256500	11022	Bivalent ligand 800	BMM4|bivalent_ligand_800	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: BMM4 (MDM2:Nutlin-3 --- BCL-XL:ABT-263)	-
34239	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cheng W (2023)	36906965	256503	11023	Bivalent ligand 801	ha-PROTAC 9|bivalent_ligand_801	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: ha-PROTAC 9 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34241	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cheng W (2023)	36906965	256503	11024	Bivalent ligand 802	ha-PROTAC 10|bivalent_ligand_802	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: ha-PROTAC 10 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34243	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng M (2023)	36898968	256504	11025	Bivalent ligand 803	TMX-4153|bivalent_ligand_803	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122928	79837	-	PIP4K2C	PIP5K2C	9606	Homo sapiens	target	Standardized BVL Name: TMX-4153 (VHL:VHL ligand --- PIP4K2C:TMX-4140 )	-
34245	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou Z (2023)	36897932	256505	11026	Bivalent ligand 804	ZZ151|bivalent_ligand_804	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112537	6654	-	SOS1	GF1|GGF1|GINGF|HGF|NS4	9606	Homo sapiens	target	Standardized BVL Name: ZZ151 (VHL:VHL ligand --- SOS1:BI-3406)	-
34247	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jarusiewicz JA (2023)	36793425	256510	11027	Bivalent ligand 805	SJ34739/PD-PROTAC 2|bivalent_ligand_805	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SJ34739/PD-PROTAC 2 (CRBN:phenyl dihydrouracil (PD) --- LCK:dasatinib)	-
34249	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jarusiewicz JA (2023)	36793425	256510	11028	Bivalent ligand 806	SJ42176/thal-PROTAC 3|bivalent_ligand_806	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SJ42176/thal-PROTAC 3 (CRBN:thalidamide) --- LCK:dasatinib)	-
34251	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jarusiewicz JA (2023)	36793425	256510	11029	Bivalent ligand 807	SJ34769/PG-PROTAC 4|bivalent_ligand_807	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SJ34769/PG-PROTAC 4 (CRBN:phenyl glutarimide (PG) --- LCK:dasatinib)	-
34253	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Jarusiewicz JA (2023)	36793425	256510	11030	Bivalent ligand 808	SJ43489/PD-PROTAC 5|bivalent_ligand_808	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SJ43489/PD-PROTAC 5 (CRBN:phenyl dihydrouracil (PD) --- LCK:dasatinib)	-
34255	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2022)	36001679	256518	11031	Bivalent ligand 809	SJ11646|bivalent_ligand_809	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: SJ11646 (CRBN:phenyl glutarimide (PG) --- LCK:dasatinib)	-
34257	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2022)	36001679	256518	11031	Bivalent ligand 809	SJ11646|bivalent_ligand_809	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: SJ11646 (CRBN:phenyl glutarimide (PG) --- CSK:dasatinib)	-
34259	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2022)	36001679	256518	11031	Bivalent ligand 809	SJ11646|bivalent_ligand_809	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	target	Standardized BVL Name: SJ11646 (CRBN:phenyl glutarimide (PG) --- SRC:dasatinib)	-
34261	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cubillos-Rojas M (2023)	36765568	256520	11032	Bivalent ligand 810	NR-11c|bivalent_ligand_810	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: NR-11c (VHL:VHL ligand --- MAPK14:PH-797804)	-
34263	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited e3 ligase	Pei J (2023)	36750097	256521	11033	Bivalent ligand 811	Conjugate 955|bivalent_ligand_811	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: Conjugate 955 (KEAP1:piperlongumine (PL) --- CDK9:SNS-032)	-
34265	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited e3 ligase	Pei J (2023)	36750097	256521	11033	Bivalent ligand 811	Conjugate 955|bivalent_ligand_811	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114128	8558	-	CDK10	PISSLRE	9606	Homo sapiens	target	Standardized BVL Name: Conjugate 955 (KEAP1:piperlongumine (PL) --- CDK10:SNS-032)	-
34267	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	degradation	recruited e3 ligase	Pei J (2023)	36750097	256521	11034	Bivalent ligand 812	Conjugate 819|bivalent_ligand_812	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: Conjugate 819 (KEAP1:piperlongumine (PL) --- EML4-ALK:ceritinib)	-
34269	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107116	648	RP11-573G6.1	BMI1	FLVI2/BMI1|PCGF4|RNF51	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- BMI1:EED226)	-
34271	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111972	6045	GS1-120K12.1	RNF2	BAP-1|BAP1|DING|HIPI3|RING1B|RING2	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- RING1B:EED226)	-
34273	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- EED:EED226)	-
34275	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kaneshige A (2023)	36735833	256523	11036	Bivalent ligand 814	AK-2292|bivalent_ligand_814	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112653	6776	-	STAT5A	MGF|STAT5	9606	Homo sapiens	target	Standardized BVL Name: AK-2292 (CRBN:lenalidomide analogue --- STAT5A:phosphotyrosine mimetic STAT5/6 inhibitor 12)	-
34277	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Kaneshige A (2023)	36735833	256523	11036	Bivalent ligand 814	AK-2292|bivalent_ligand_814	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112654	6777	-	STAT5B	STAT5	9606	Homo sapiens	target	Standardized BVL Name: AK-2292 (CRBN:lenalidomide analogue --- STAT5B:phosphotyrosine mimetic STAT5/6 inhibitor 12)	-
34279	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	O'Herin CB (2023)	36735827	256525	11037	Bivalent ligand 815	Degrader 11|bivalent_ligand_815	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107215	760	-	CA2	CA-II|CAC|CAII|Car2|HEL-76	9606	Homo sapiens	target	Standardized BVL Name: Degrader 11 (CRBN:pomalidomide --- CA2:p-sulfamoyl benzamide metal binding pharmacophore (MBP) moiety)	-
34281	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	He R (2023)	36695404	256526	11038	Bivalent ligand 816	compound 6n|bivalent_ligand_816	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	target	Standardized BVL Name: compound 6n (CRBN:lenalidomide --- AXL:HH30134 analogue 9im)	-
34283	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Chen JJ (2023)	36692137	256527	11039	Bivalent ligand 817	PRO-6 E|bivalent_ligand_817	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PRO-6 E (CRBN:pomalidomide --- MET:Crizotinib)	-
34285	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	degradation	recruited e3 ligase	Cruite JT (2022)	36128501	256671	11040	Bivalent ligand 818	EM12-FS|bivalent_ligand_818	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120405	55093	-	WDYHV1	C8orf32	9606	Homo sapiens	target	Standardized BVL Name: EM12-FS (CRBN:EM12-FS --- NTAQ1:EM12-FS)	-
