#BIOGRID ID	ENTREZ GENE ID	SYSTEMATIC NAME	OFFICIAL SYMBOL	SYNONYMS	ORGANISM ID	ORGANISM NAME	INTERACTION COUNT	PTM COUNT	CHEMICAL INTERACTION COUNT	SOURCE	CATEGORY VALUES	CATEGORY IDS	CATEGORY TAGS	CATEGORY EVIDENCE VALUES	CATEGORY EVIDENCE IDS	CATEGORY EVIDENCE CLASSES	CATEGORY EVIDENCE METHODS	PFAM DOMAIN VALUES	PFAM DOMAIN IDS	PFAM DOMAIN TAGS	PFAM DOMAIN EVIDENCE VALUES	PFAM DOMAIN EVIDENCE IDS	PFAM DOMAIN EVIDENCE CLASSES	PFAM DOMAIN EVIDENCE METHODS
117078	23532	-	PRAME	CT130|MAPE|OIP-4|OIP4	9606	Homo sapiens	209	132	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
127870	163590	RP11-12M5.5	TOR1AIP2	IFRG15|LULL1|NET9	9606	Homo sapiens	372	41	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LAP1C	PF05609	-	-	-	-	-
32232	851759	YDR179C	CSN9	S000007578	559292	Saccharomyces cerevisiae (S288c)	180	0	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	-	-	-	-	-	-	-
32230	851757	YDR177W	UBC1	E2 ubiquitin-conjugating protein UBC1|L000002406	559292	Saccharomyces cerevisiae (S288c)	227	5	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UBA_3|UQ_con	PF09288|PF00179	-	-	-	-	-
32235	851762	YDR181C	SAS4	L000004214	559292	Saccharomyces cerevisiae (S288c)	251	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SAS4	PF15460	-	-	-	-	-
114079	8507	-	ENC1	CCL28|ENC-1|KLHL35|KLHL37|NRPB|PIG10|TP53I10	9606	Homo sapiens	48	58	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
131448	347541	-	MAGEB5	CT3.3|MAGE-B5	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
120617	55336	-	FBXL8	FBL8	9606	Homo sapiens	26	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
32529	852088	YDR477W	SNF1	CAT1|CCR1|GLC2|HAF3|PAS14|AMP-activated serine/threonine-protein kinase catalytic subunit SNF1|L000001944	559292	Saccharomyces cerevisiae (S288c)	1459	41	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	AdenylateSensor|Pkinase|UBA_2	PF16579|PF00069|PF08587	-	-	-	-	-
33644	853332	YJL112W	MDV1	FIS2|GAG3|NET2	559292	Saccharomyces cerevisiae (S288c)	218	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Mdv1|WD40	PF11542|PF00400	-	-	-	-	-
32305	851842	YDR255C	RMD5	GID2|ubiquitin-protein ligase RMD5	559292	Saccharomyces cerevisiae (S288c)	113	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
32656	852239	YBL041W	PRE7	PRS3|proteasome core particle subunit beta 6|L000002699	559292	Saccharomyces cerevisiae (S288c)	618	11	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
32650	852233	YBL047C	EDE1	BUD15	559292	Saccharomyces cerevisiae (S288c)	593	102	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EF-hand_4|UBA	PF12763|PF00627	-	-	-	-	-
113159	7311	-	UBA52	CEP52|HUBCEP52|L40|RPL40	9606	Homo sapiens	521	195	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	Ribosomal_L40e|ubiquitin	PF01020|PF00240	-	-	-	-	-
120434	55128	-	TRIM68	GC109|RNF137|SS-56|SS56	9606	Homo sapiens	163	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	413	325	4	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	KA1|Pkinase|UBA	PF02149|PF00069|PF00627	-	-	-	-	-
114672	9246	-	UBE2L6	RIG-B|UBCH8	9606	Homo sapiens	154	9	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
130885	339451	RP11-54O7.6	KLHL17	-	9606	Homo sapiens	30	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
117412	25906	HSPC020	ANAPC15	APC15|C11orf51	9606	Homo sapiens	170	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC15	PF15243	-	-	-	-	-
119468	51317	BM-006	PHF21A	BHC80	9606	Homo sapiens	418	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD	PF00628	-	-	-	-	-
35436	855300	YMR258C	ROY1	-	559292	Saccharomyces cerevisiae (S288c)	85	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
126870	144699	-	FBXL14	Fbl14	9606	Homo sapiens	79	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
31914	851408	YDL147W	RPN5	NAS5|proteasome regulatory particle lid subunit RPN5|L000004451|L000004305	559292	Saccharomyces cerevisiae (S288c)	1065	9	0	BIOGRID	NEDD8-specific protease|Proteasome	-	-	-	-	-	-	PCI|RPN5_C	PF01399|PF18098	-	-	-	-	-
124009	84282	L13	RNF135	MMFD|REUL|Riplet	9606	Homo sapiens	69	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
124007	84280	-	BTBD10	GMRP-1|GMRP1	9606	Homo sapiens	33	54	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_3	PF16017	-	-	-	-	-
32786	852376	YBR082C	UBC4	E2 ubiquitin-conjugating protein UBC4|L000002407	559292	Saccharomyces cerevisiae (S288c)	827	5	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
121890	59349	-	KLHL12	C3IP1|DKIR	9606	Homo sapiens	277	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
36208	856142	YPR030W	CSR2	ART8|MRG19|S000007450	559292	Saccharomyces cerevisiae (S288c)	191	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C	PF02752	-	-	-	-	-
125884	124739	-	USP43	-	9606	Homo sapiens	83	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
128900	246330	-	PELI3	-	9606	Homo sapiens	68	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pellino	PF04710	-	-	-	-	-
116784	23172	-	FAM175B	ABRO1|KIAA0157	9606	Homo sapiens	195	28	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
608820	728393	-	USP17L27	-	9606	Homo sapiens	2	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
608827	728400	-	USP17L28	-	9606	Homo sapiens	1	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
124917	92181	SB72	UBTD2	DCUBP	9606	Homo sapiens	50	14	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBD|ubiquitin	PF16455|PF00240	-	-	-	-	-
121521	57448	-	BIRC6	APOLLON|BRUCE	9606	Homo sapiens	434	697	0	BIOGRID	Ubiquitin conjugating enzyme (E2)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR|BIRC6|UQ_con	PF00653|PF12356|PF00179	-	-	-	-	-
107532	1107	-	CHD3	Mi-2a|Mi2-ALPHA|ZFH	9606	Homo sapiens	1026	237	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CHDCT2|CHDNT|Chromo|DUF1086|DUF1087|Helicase_C|PHD|SNF2_N	PF08074|PF08073|PF00385|PF06461|PF06465|PF00271|PF00628|PF00176	-	-	-	-	-
107533	1108	-	CHD4	CHD-4|Mi-2b|Mi2-BETA	9606	Homo sapiens	1530	664	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CHDCT2|CHDNT|Chromo|DUF1086|DUF1087|Helicase_C|PHD|SNF2_N	PF08074|PF08073|PF00385|PF06461|PF06465|PF00271|PF00628|PF00176	-	-	-	-	-
124754	90678	UNQ6496/PRO21356	LRSAM1	CMT2P|RIFLE|TAL	9606	Homo sapiens	122	107	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_8|SAM_2	PF13855|PF07647	-	-	-	-	-
124751	90665	-	TBL1Y	TBL1	9606	Homo sapiens	69	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LisH|WD40	PF08513|PF00400	-	-	-	-	-
113171	7323	-	UBE2D3	E2(17)KB3|UBC4/5|UBCH5C	9606	Homo sapiens	849	49	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113170	7322	-	UBE2D2	E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B	9606	Homo sapiens	988	5	3	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113173	7325	-	UBE2E2	UBCH8	9606	Homo sapiens	171	29	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113172	7324	-	UBE2E1	UBCH6	9606	Homo sapiens	309	17	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113175	7327	-	UBE2G2	UBC7	9606	Homo sapiens	169	18	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113174	7326	-	UBE2G1	E217K|UBC7|UBE2G	9606	Homo sapiens	67	9	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
117326	25793	LL22NC03-28H9.2	FBXO7	FBX|FBX07|FBX7|PARK15|PKPS	9606	Homo sapiens	811	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|PI31_Prot_N	PF12937|PF11566	-	-	-	-	-
113176	7328	-	UBE2H	E2-20K|GID3|UBC8|UBCH|UBCH2	9606	Homo sapiens	2014	21	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
116231	11043	RP6-191P20.2	MID2	FXY2|MRX101|RNF60|TRIM1	9606	Homo sapiens	407	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	COS|SPRY|zf-B_box|zf-RING_UBOX	PF18568|PF00622|PF00643|PF13445	-	-	-	-	-
36337	856293	YPR164W	MMS1	RTT108|SLM6|L000003933	559292	Saccharomyces cerevisiae (S288c)	486	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	557	192	5	BIOGRID	Proteasome|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Proteasom_Rpn13|RPN13_C	PF04683|PF16550	-	-	-	-	-
125405	114987	-	WDR31	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
33478	853140	YGR225W	AMA1	SPO70|L000004668	559292	Saccharomyces cerevisiae (S288c)	98	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
121411	57154	-	SMURF1	-	9606	Homo sapiens	867	23	4	BIOGRID	NEDD8 E3|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
121417	57161	-	PELI2	-	9606	Homo sapiens	75	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pellino	PF04710	-	-	-	-	-
121415	57159	-	TRIM54	MURF|MURF-3|RNF30|muRF3	9606	Homo sapiens	382	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
121418	57162	-	PELI1	-	9606	Homo sapiens	132	22	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pellino	PF04710	-	-	-	-	-
116124	10920	-	COPS8	COP9|CSN8|SGN8	9606	Homo sapiens	326	5	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	CSN8_PSD8_EIF3K	PF10075	-	-	-	-	-
116121	10916	RP1-14O9.1	MAGED2	11B6|BCG-1|BCG1|HCA10|MAGE-D2	9606	Homo sapiens	320	103	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
36844	856835	YER098W	UBP9	L000003170	559292	Saccharomyces cerevisiae (S288c)	143	3	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
121096	56163	RP11-756A22.1	RNF17	Mmip-2|SPATA23|TDRD4	9606	Homo sapiens	14	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TUDOR	PF00567	-	-	-	-	-
36846	856837	YER100W	UBC6	DOA2|E2 ubiquitin-conjugating protein UBC6|L000002409	559292	Saccharomyces cerevisiae (S288c)	255	10	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
121094	56160	-	NDNL2	HCA4|MAGEG1|MAGEL3|NSE3|NSMCE3	9606	Homo sapiens	110	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
36840	856830	YER094C	PUP3	SCS32|proteasome core particle subunit beta 3|L000001532	559292	Saccharomyces cerevisiae (S288c)	598	14	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
118937	29882	RP11-350O14.5	ANAPC2	APC2	9606	Homo sapiens	421	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC2|Cullin	PF08672|PF00888	-	-	-	-	-
122544	79097	-	TRIM48	RNF101	9606	Homo sapiens	5	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box	PF00643	-	-	-	-	-
123817	83932	RP5-876B10.3	SPRTN	C1orf124|DDDL1880|DVC1|PRO4323|Spartan|dJ876B10.3	9606	Homo sapiens	695	95	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SprT-like	PF10263	-	-	-	-	-
122548	79101	-	TAF1D	JOSD3|RAFI41|TAF(I)41|TAFI41	9606	Homo sapiens	146	6	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	TAF1D	PF15333	-	-	-	-	-
122549	79102	-	RNF26	-	9606	Homo sapiens	167	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
34971	854795	YIL017C	VID28	GID5|YIL017W|glucose-induced degradation complex subunit VID28	559292	Saccharomyces cerevisiae (S288c)	300	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121705	57674	hCG_1812857	RNF213	ALO17|C17orf27|KIAA1618|MYMY2|MYSTR|NET57	9606	Homo sapiens	232	304	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4	PF00097	-	-	-	-	-
118807	28986	-	MAGEH1	APR-1|APR1|MAGEH	9606	Homo sapiens	27	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
123964	84231	-	TRAF7	RFWD1|RNF119	9606	Homo sapiens	225	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40|zf-RING_UBOX	PF00400|PF13445	-	-	-	-	-
33672	853361	YJL084C	ALY2	ART3	559292	Saccharomyces cerevisiae (S288c)	171	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
109533	3300	-	DNAJB2	DSMA5|HSJ-1|HSJ1|HSPF3	9606	Homo sapiens	186	23	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DnaJ	PF00226	-	-	-	-	-
33504	853168	YGR253C	PUP2	DOA5|proteasome core particle subunit alpha 5|L000001531	559292	Saccharomyces cerevisiae (S288c)	363	15	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
33854	853562	YJR099W	YUH1	L000002565	559292	Saccharomyces cerevisiae (S288c)	142	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C12	PF01088	-	-	-	-	-
119261	51070	CGI-25	NOSIP	-	9606	Homo sapiens	139	117	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-NOSIP	PF15906	-	-	-	-	-
115021	9666	-	DZIP3	PPP1R66|UURF2|hRUL138	9606	Homo sapiens	214	223	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF5861|HEPN_DZIP3|zf-RING_2	PF19179|PF18738|PF13639	-	-	-	-	-
108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	1463	41	7	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CPSF_A	PF03178	-	-	-	-	-
123701	83637	HRIHFB2007	ZMIZ2	NET27|TRAFIP20|ZIMP7|hZIMP7	9606	Homo sapiens	75	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-MIZ	PF02891	-	-	-	-	-
115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	1330	53	229	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Hist_deacetyl|zf-UBP	PF00850|PF02148	-	-	-	-	-
136847	440730	-	TRIM67	TNL	9606	Homo sapiens	4996	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|fn3|zf-B_box|zf-C3HC4	PF00622|PF00041|PF00643|PF00097	-	-	-	-	-
115249	9921	-	RNF10	RIE2	9606	Homo sapiens	462	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
115248	9920	-	KBTBD11	KLHDC7C	9606	Homo sapiens	10	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Kelch_1	PF00651|PF01344	-	-	-	-	-
35156	854995	YML013W	UBX2	SEL1	559292	Saccharomyces cerevisiae (S288c)	649	25	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	UBX	PF00789	-	-	-	-	-
109991	3790	-	KCNS3	KV9.3	9606	Homo sapiens	117	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
123141	80149	RP3-423B22.1	ZC3H12A	MCPIP|MCPIP1|dJ423B22.1	9606	Homo sapiens	69	17	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	RNase_Zc3h12a|Regnase_1_C|UBA_6	PF11977|PF18561|PF18039	-	-	-	-	-
34376	854133	YOL025W	LAG2	ECM36|L000003402	559292	Saccharomyces cerevisiae (S288c)	99	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111832	5896	-	RAG1	RAG-1|RNF74	9606	Homo sapiens	61	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAG1|RAG1_imp_bd|zf-RAG1	PF12940|PF12560|PF10426	-	-	-	-	-
126044	127247	-	ASB17	Asb-17	9606	Homo sapiens	26	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box	PF07525	-	-	-	-	-
126262	130888	-	FBXO36	Fbx36	9606	Homo sapiens	6	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
127392	151636	-	DTX3L	BBAP	9606	Homo sapiens	120	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DTC	PF18102	-	-	-	-	-
132019	377630	-	USP17L2	DUB-3|DUB3|USP17	9606	Homo sapiens	84	1	2	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
132015	377007	-	KLHL30	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	924	18	10	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
34553	854328	YOR157C	PUP1	proteasome core particle subunit beta 2|L000001530	559292	Saccharomyces cerevisiae (S288c)	494	4	0	BIOGRID	Proteasome	-	-	-	-	-	-	Pr_beta_C|Proteasome	PF12465|PF00227	-	-	-	-	-
123035	79968	-	WDR76	CDW14	9606	Homo sapiens	559	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111947	6015	DADB-100D22.6	RING1	RING1A|RNF1	9606	Homo sapiens	508	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
34153	853891	YKR021W	ALY1	ART6	559292	Saccharomyces cerevisiae (S288c)	92	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C	PF02752	-	-	-	-	-
126603	140432	-	RNF113B	RNF161|ZNF183L1|bA10G5.1	9606	Homo sapiens	8	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CCCH	PF00642	-	-	-	-	-
128745	221687	-	RNF182	-	9606	Homo sapiens	18	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
115803	10552	-	ARPC1A	Arc40|HEL-68|SOP2Hs|SOP2L	9606	Homo sapiens	189	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
120429	55120	-	FANCL	FAAP43|PHF9|POG	9606	Homo sapiens	197	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FANCL_C|FANCL_d1|FANCL_d2|FANCL_d3	PF11793|PF09765|PF18890|PF18891	-	-	-	-	-
116939	23358	hCG_33036	USP24	-	9606	Homo sapiens	153	149	2	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DUF3517|UCH	PF12030|PF00443	-	-	-	-	-
116937	23355	-	VPS8	KIAA0804	9606	Homo sapiens	102	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Vps8	PF12816	-	-	-	-	-
116934	23352	RP5-1126H10.1	UBR4	RBAF600|ZUBR1|p600	9606	Homo sapiens	469	897	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	E3_UbLigase_R4|zf-UBR	PF13764|PF02207	-	-	-	-	-
110309	4139	-	MARK1	MARK|Par-1c|Par1c	9606	Homo sapiens	124	86	2	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	KA1|Pkinase|UBA	PF02149|PF00069|PF00627	-	-	-	-	-
117401	25893	-	TRIM58	BIA2	9606	Homo sapiens	45	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
35442	855306	YMR264W	CUE1	KIS4|L000003518	559292	Saccharomyces cerevisiae (S288c)	306	2	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE|Cue1_U7BR	PF02845|PF18499	-	-	-	-	-
117405	25897	-	RNF19A	RNF19	9606	Homo sapiens	44	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
117406	25898	-	RCHY1	ARNIP|CHIMP|PIRH2|PRO1996|RNF199|ZCHY|ZNF363	9606	Homo sapiens	444	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CHY|zf-RING_2|zinc_ribbon_6	PF05495|PF13639|PF14599	-	-	-	-	-
118150	27338	OK/SW-cl.73	UBE2S	E2-EPF|E2EPF|EPF5	9606	Homo sapiens	308	17	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
118151	27339	-	PRPF19	NMP200|PRP19|PSO4|SNEV|UBOX4|hPSO4	9606	Homo sapiens	778	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Prp19|U-box|WD40	PF08606|PF04564|PF00400	-	-	-	-	-
118154	27342	-	RABGEF1	RABEX5|RAP1|rabex-5	9606	Homo sapiens	294	501	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF5601|VPS9|zf-A20	PF18151|PF02204|PF01754	-	-	-	-	-
120738	55593	-	OTUD5	DUBA	9606	Homo sapiens	108	154	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
120732	55585	PRO3094	UBE2Q1	GTAP|NICE-5|UBE2Q	9606	Homo sapiens	77	9	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
36238	856179	YPR066W	UBA3	NEDD8-activating protein UBA3|L000004373	559292	Saccharomyces cerevisiae (S288c)	411	1	0	BIOGRID	NEDD8 E1	-	-	-	-	-	-	ThiF	PF00899	-	-	-	-	-
116331	11160	UNQ2441	ERLIN2	C8orf2|Erlin-2|NET32|SPFH2|SPG18	9606	Homo sapiens	516	17	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Band_7	PF01145	-	-	-	-	-
131307	344558	-	SH3RF3	POSH2|SH3MD4	9606	Homo sapiens	69	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH3_1|SH3_9|zf-C3HC4	PF00018|PF14604|PF00097	-	-	-	-	-
121958	60685	RP1-295F6.1	ZFAND3	TEX27	9606	Homo sapiens	17	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-A20|zf-AN1	PF01754|PF01428	-	-	-	-	-
608832	728405	-	USP17L29	-	9606	Homo sapiens	2	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
120139	54764	RP11-298J20.4	ZRANB1	TRABID	9606	Homo sapiens	4428	20	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	AnkUBD|OTU|zf-RanBP	PF18418|PF02338|PF00641	-	-	-	-	-
121553	57484	-	RNF150	-	9606	Homo sapiens	21	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
107527	1102	-	RCBTB2	CHC1L|RLG	9606	Homo sapiens	68	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|RCC1	PF00651|PF00415	-	-	-	-	-
128288	199990	RP11-181G12.3	C1orf86	FAAP20|FP7162	9606	Homo sapiens	129	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	FANCA_interact|UBZ_FAAP20	PF15751|PF15750	-	-	-	-	-
113546	7763	RP11-63P12.8	ZFAND5	ZA20D2|ZFAND5A|ZNF216	9606	Homo sapiens	44	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-A20|zf-AN1	PF01754|PF01428	-	-	-	-	-
116759	23142	-	DCUN1D4	-	9606	Homo sapiens	52	4	0	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
117339	25807	CTA-984G1.4	RHBDD3	C22orf3|HS984G1A|PTAG	9606	Homo sapiens	55	6	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Rhomboid|UBA	PF01694|PF00627	-	-	-	-	-
126648	140685	-	ZBTB46	BTBD4|BZEL|RINZF|ZNF340|dJ583P15.7|dJ583P15.8	9606	Homo sapiens	64	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
134376	399664	-	MEX3D	MEX-3D|MEX3|OK/SW-cl.4|RKHD1|RNF193|TINO	9606	Homo sapiens	52	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	KH_1	PF00013	-	-	-	-	-
35119	854956	YML049C	RSE1	L000004030	559292	Saccharomyces cerevisiae (S288c)	398	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CPSF_A	PF03178	-	-	-	-	-
125419	115207	-	KCTD12	C13orf2|PFET1|PFETIN	9606	Homo sapiens	167	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
125416	115123	-	MARCH3	MARCH-III|RNF173	9606	Homo sapiens	53	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
121170	56658	DAAP-385L22.4	TRIM39	RNF23|TFP|TRIM39B	9606	Homo sapiens	206	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
124430	85015	RP11-98I9.5	USP45	-	9606	Homo sapiens	59	35	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
36541	856508	YHR108W	GGA2	S000007494	559292	Saccharomyces cerevisiae (S288c)	304	14	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Alpha_adaptinC2|GAT|VHS	PF02883|PF03127|PF00790	-	-	-	-	-
112300	6400	UNQ128/PRO1063	SEL1L	PRO1063|SEL1-LIKE|SEL1L1	9606	Homo sapiens	412	12	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Sel1|fn2	PF08238|PF00040	-	-	-	-	-
116115	10910	RP11-93H24.2	SUGT1	SGT1	9606	Homo sapiens	438	94	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CS|SGS	PF04969|PF05002	-	-	-	-	-
36548	856515	YHR115C	DMA1	CHF1|ubiquitin-conjugating protein DMA1|S000029719	559292	Saccharomyces cerevisiae (S288c)	143	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FHA|zf-RING_11	PF00498|PF17123	-	-	-	-	-
35093	854929	YML111W	BUL2	ubiquitin-ubiquitin ligase BUL2|L000004755	559292	Saccharomyces cerevisiae (S288c)	312	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bul1_C|Bul1_N	PF04426|PF04425	-	-	-	-	-
36832	856821	YER087C-B	SBH1	SEB1|YER087C-A|Arf family guanine nucleotide exchange factor SBH1|L000002846|L000004137	559292	Saccharomyces cerevisiae (S288c)	271	6	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Sec61_beta	PF03911	-	-	-	-	-
112945	7090	-	TLE3	ESG|ESG3|GRG3|HsT18976	9606	Homo sapiens	487	230	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TLE_N|WD40	PF03920|PF00400	-	-	-	-	-
112944	7089	-	TLE2	ESG|ESG2|GRG2	9606	Homo sapiens	173	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TLE_N|WD40	PF03920|PF00400	-	-	-	-	-
112943	7088	RP11-203D19.1	TLE1	ESG|ESG1|GRG1	9606	Homo sapiens	319	81	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TLE_N|WD40	PF03920|PF00400	-	-	-	-	-
122559	79139	UNQ243/PRO276	DERL1	DER-1|DER1	9606	Homo sapiens	621	1	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	DER1	PF04511	-	-	-	-	-
126820	143879	-	KBTBD3	BKLHD3	9606	Homo sapiens	10	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
107709	1314	-	COPA	HEP-COP	9606	Homo sapiens	589	120	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|COPI_C|Coatomer_WDAD|WD40	PF12894|PF06957|PF04053|PF00400	-	-	-	-	-
34944	854765	YIL046W	MET30	ZRG11|L000001093	559292	Saccharomyces cerevisiae (S288c)	662	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
121779	57820	-	CCNB1IP1	C14orf18|HEI10	9606	Homo sapiens	35	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_5	PF14634	-	-	-	-	-
134882	401036	-	ASB18	ASB-18	9606	Homo sapiens	26	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
121771	57799	LA16c-398G5.1	RAB40C	RARL|RASL8C	9606	Homo sapiens	68	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ras|SOCS_box	PF00071|PF07525	-	-	-	-	-
113892	8287	-	USP9Y	DFFRY|SPGFY2	9606	Homo sapiens	84	64	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUF3517|UCH	PF12030|PF00443	-	-	-	-	-
119216	51009	CGI-101	DERL2	F-LAN-1|F-LANa|FLANa	9606	Homo sapiens	218	5	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	DER1	PF04511	-	-	-	-	-
115013	9655	-	SOCS5	CIS6|CISH6|Cish5|SOCS-5	9606	Homo sapiens	218	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS|SOCS_box	PF00017|PF12610|PF07525	-	-	-	-	-
610365	729974	-	RFPL4AL1	-	9606	Homo sapiens	0	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|RDM|SPRY	PF13765|PF11002|PF00622	-	-	-	-	-
129420	282808	LL0XNC01-237H1.1	RAB40AL	MRXSMP|RAR2|RLGP	9606	Homo sapiens	51	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ras|SOCS_box	PF00071|PF07525	-	-	-	-	-
129421	282809	-	POC1B	CORD20|PIX1|TUWD12|WDR51B	9606	Homo sapiens	136	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
121601	57542	-	KLHL42	Ctb9|KLHDC5	9606	Homo sapiens	143	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|Kelch_1	PF07707|PF01344	-	-	-	-	-
122157	64400	-	AKTIP	FT1|FTS	9606	Homo sapiens	181	6	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
122152	64395	-	GMCL1	BTBD13|GCL|GCL1|SPATA29	9606	Homo sapiens	284	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB	PF07707|PF00651	-	-	-	-	-
115492	10197	-	PSME3	HEL-S-283|Ki|PA28-gamma|PA28G|PA28gamma|REG-GAMMA	9606	Homo sapiens	761	57	0	BIOGRID	Proteasome	-	-	-	-	-	-	PA28_alpha|PA28_beta	PF02251|PF02252	-	-	-	-	-
33991	853712	YKL145W	RPT1	CIM5|YTA3|proteasome regulatory particle base subunit RPT1|L000002557	559292	Saccharomyces cerevisiae (S288c)	1190	33	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3	PF00004|PF17862	-	-	-	-	-
34894	854710	YIL097W	FYV10	GID9|glucose-induced degradation complex subunit FYV10	559292	Saccharomyces cerevisiae (S288c)	390	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
126611	140458	-	ASB5	ASB-5	9606	Homo sapiens	23	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
109989	3788	-	KCNS2	KV9.2	9606	Homo sapiens	10	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
109988	3787	-	KCNS1	KV9.1	9606	Homo sapiens	2	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
123608	81858	PSEC0216	SHARPIN	SIPL1	9606	Homo sapiens	343	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sharpin_PH	PF16764	-	-	-	-	-
119324	51138	-	COPS4	CSN4	9606	Homo sapiens	439	36	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	CSN4_RPN5_eIF3a|PCI	PF18420|PF01399	-	-	-	-	-
119323	51136	PTD016	RNFT1	-	9606	Homo sapiens	42	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
119320	51133	RP11-5F19.1	KCTD3	NY-REN-45	9606	Homo sapiens	222	36	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
114872	9491	RP4-545L17.1	PSMF1	PI31	9606	Homo sapiens	170	26	0	BIOGRID	Proteasome	-	-	-	-	-	-	PI31_Prot_C|PI31_Prot_N	PF08577|PF11566	-	-	-	-	-
34097	853832	YKL034W	TUL1	ubiquitin-protein ligase TUL1	559292	Saccharomyces cerevisiae (S288c)	140	1	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-rbx1	PF12678	-	-	-	-	-
114879	9500	PRO2292	MAGED1	DLXIN-1|NRAGE	9606	Homo sapiens	391	205	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
31208	850611	YFR050C	PRE4	proteasome core particle subunit beta 7|L000001486	559292	Saccharomyces cerevisiae (S288c)	671	5	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
111823	5886	-	RAD23A	HHR23A|HR23A	9606	Homo sapiens	474	51	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|XPC-binding|ubiquitin	PF00627|PF09280|PF00240	-	-	-	-	-
111824	5887	RP11-131A5.1	RAD23B	HHR23B|HR23B|P58	9606	Homo sapiens	394	50	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|XPC-binding|ubiquitin	PF00627|PF09280|PF00240	-	-	-	-	-
131043	340359	-	KLHL38	C8ORFK36	9606	Homo sapiens	103	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
31571	851015	YLR306W	UBC12	NEDD8-conjugating protein UBC12|L000003386	559292	Saccharomyces cerevisiae (S288c)	176	0	0	BIOGRID	NEDD8 E2	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
127386	151525	-	WDSUB1	UBOX6|WDSAM1	9606	Homo sapiens	4	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SAM_2|U-box|WD40	PF07647|PF04564|PF00400	-	-	-	-	-
126384	134111	-	UBE2QL1	-	9606	Homo sapiens	24	1	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
35140	854979	YML029W	USA1	L000003225	559292	Saccharomyces cerevisiae (S288c)	208	16	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
115272	9947	RP6-232G24.1	MAGEC1	CT7|CT7.1	9606	Homo sapiens	20	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
127813	162333	-	MARCH10	MARCH-X|RNF190	9606	Homo sapiens	10	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
114054	8480	RP4-800J21.2	RAE1	MIG14|MRNP41|Mnrp41|dJ481F12.3|dJ800J21.1	9606	Homo sapiens	403	121	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
126615	140462	-	ASB9	-	9606	Homo sapiens	117	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
117651	26267	hCG_2011110	FBXO10	FBX10|PRMT11	9606	Homo sapiens	57	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Beta_helix|F-box-like|NosD	PF13229|PF12937|PF05048	-	-	-	-	-
117652	26268	-	FBXO9	FBX9|NY-REN-57|VCIA1|dJ341E18.2	9606	Homo sapiens	35	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
117653	26269	DC10	FBXO8	FBS|FBX8	9606	Homo sapiens	34	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|Sec7	PF12937|PF01369	-	-	-	-	-
117654	26270	RP3-330O12.3	FBXO6	FBG2|FBS2|FBX6|Fbx6b	9606	Homo sapiens	1030	22	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|FBA	PF12937|PF04300	-	-	-	-	-
117655	26271	RP1-101K10.5	FBXO5	EMI1|FBX5|Fbxo31	9606	Homo sapiens	145	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
117656	26272	-	FBXO4	FBX4	9606	Homo sapiens	107	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
117657	26273	-	FBXO3	FBA|FBX3	9606	Homo sapiens	110	56	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF525|F-box-like|SMI1_KNR4	PF04379|PF12937|PF09346	-	-	-	-	-
115872	10628	RP11-315I20.4	TXNIP	EST01027|HHCPA78|THIF|VDUP1	9606	Homo sapiens	328	45	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
110150	3959	-	LGALS3BP	90K|BTBD17B|CyCAP|M2BP|MAC-2-BP|TANGO10B|gp90	9606	Homo sapiens	454	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|SRCR	PF07707|PF00530	-	-	-	-	-
31370	850786	YLR097C	HRT3	SCF ubiquitin ligase complex subunit HRT3	559292	Saccharomyces cerevisiae (S288c)	90	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
32817	852411	YBR114W	RAD16	PSO5|DNA repair protein RAD16|L000004121|L000001565	559292	Saccharomyces cerevisiae (S288c)	178	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Helicase_C|SNF2_N|zf-C3HC4	PF00271|PF00176|PF00097	-	-	-	-	-
120387	55070	-	DET1	-	9606	Homo sapiens	244	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Det1	PF09737	-	-	-	-	-
116431	11275	-	KLHL2	ABP-KELCH|MAV|MAYVEN	9606	Homo sapiens	217	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
116430	11274	-	USP18	ISG43|UBP43	9606	Homo sapiens	124	5	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
120389	55072	-	RNF31	HOIP|ZIBRA	9606	Homo sapiens	802	30	1	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	E3_UbLigase_RBR|HOIP-UBA|IBR|PUB|PUB_1	PF18091|PF16678|PF01485|PF09409|PF18486	-	-	-	-	-
127720	158880	-	USP51	-	9606	Homo sapiens	73	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
110378	4214	-	MAP3K1	MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6	9606	Homo sapiens	244	25	9	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
115488	10193	SBBI03	RNF41	FLRF|NRDP1	9606	Homo sapiens	308	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	USP8_interact	PF08941	-	-	-	-	-
122612	79269	-	DCAF10	WDR32	9606	Homo sapiens	202	35	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
114695	9278	DADB-159G18.8	ZBTB22	BING1|ZBTB22A|ZNF297|ZNF297A|fru|fruitless	9606	Homo sapiens	24	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
127354	151230	-	KLHL23	DITHP	9606	Homo sapiens	53	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
35454	855318	YMR275C	BUL1	DAG1|RDS1|SMM2|ubiquitin-ubiquitin ligase BUL1|L000002733	559292	Saccharomyces cerevisiae (S288c)	357	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bul1_C|Bul1_N	PF04426|PF04425	-	-	-	-	-
35455	855319	YMR276W	DSK2	L000002646	559292	Saccharomyces cerevisiae (S288c)	257	12	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	1701	22	6	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Beta-TrCP_D|F-box-like|WD40	PF12125|PF12937|PF00400	-	-	-	-	-
127031	147040	-	KCTD11	C17orf36|KCASH1|REN|REN/KCTD11	9606	Homo sapiens	21	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
129001	253980	FKSG86	KCTD13	BACURD1|PDIP1|POLDIP1|hBACURD1	9606	Homo sapiens	113	42	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
119537	51433	-	ANAPC5	APC5	9606	Homo sapiens	311	96	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC5	PF12862	-	-	-	-	-
117504	26038	RP1-233K16.2	CHD5	CHD-5	9606	Homo sapiens	113	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CHDCT2|CHDNT|Chromo|DUF1086|DUF1087|Helicase_C|PHD|SNF2_N	PF08074|PF08073|PF00385|PF06461|PF06465|PF00271|PF00628|PF00176	-	-	-	-	-
119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	94	89	3	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	IMS|IMS_C|IMS_HHH	PF00817|PF11799|PF11798	-	-	-	-	-
117507	26043	-	UBXN7	UBXD7	9606	Homo sapiens	377	39	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBX	PF00789	-	-	-	-	-
118004	27106	PP2703	ARRDC2	CLONE24945	9606	Homo sapiens	55	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
117509	26046	HSPC087	LTN1	C21orf10|C21orf98|RNF160|ZNF294	9606	Homo sapiens	291	52	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
118001	27101	PNAS-107	CACYBP	GIG5|S100A6BP|SIP	9606	Homo sapiens	377	71	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CS|SGS|Siah-Interact_N	PF04969|PF05002|PF09032	-	-	-	-	-
119538	51434	-	ANAPC7	APC7	9606	Homo sapiens	342	158	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TPR_8	PF13181	-	-	-	-	-
124933	92312	-	MEX3A	MEX-3A|RKHD4	9606	Homo sapiens	407	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	KH_1	PF00013	-	-	-	-	-
124932	92305	-	TMEM129	D4S2561E	9606	Homo sapiens	56	7	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Tmpp129	PF10272	-	-	-	-	-
608806	728379	-	USP17L26	-	9606	Homo sapiens	0	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
608800	728373	-	USP17L25	-	9606	Homo sapiens	0	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
120375	55054	hCG_1817841	ATG16L1	APG16L|ATG16A|ATG16L|IBD10|WDR30	9606	Homo sapiens	1378	41	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ATG16|WD40	PF08614|PF00400	-	-	-	-	-
120146	54778	-	RNF111	ARK	9606	Homo sapiens	196	84	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RNF111_N|zf-RING_2	PF15303|PF13639	-	-	-	-	-
121548	57478	RP11-20G6.3	USP31	-	9606	Homo sapiens	33	2	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
125643	119504	-	ANAPC16	APC16|C10orf104|CENP-27|MSAG|bA570G20.3	9606	Homo sapiens	166	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC16	PF17256	-	-	-	-	-
32107	851624	YDR054C	CDC34	DNA6|UBC3|SCF E2 ubiquitin-protein ligase catalytic subunit CDC34|L000000271	559292	Saccharomyces cerevisiae (S288c)	641	13	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
116741	23119	-	HIC2	HRG22|ZBTB30|ZNF907	9606	Homo sapiens	80	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
116740	23118	RP1-111D6.3	TAB2	CHTD2|MAP3K7IP2|TAB-2	9606	Homo sapiens	401	30	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
32103	851618	YDR049W	VMS1	-	559292	Saccharomyces cerevisiae (S288c)	847	4	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	bVLRF1	PF18826	-	-	-	-	-
130136	285533	-	RNF175	-	9606	Homo sapiens	6	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117348	25820	HUSSY-27	ARIH1	ARI|HARI|HHARI|UBCH7BP	9606	Homo sapiens	474	78	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
122865	79754	-	ASB13	-	9606	Homo sapiens	49	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
114405	8887	PRO0105	TAX1BP1	CALCOCO3|T6BP|TXBP151	9606	Homo sapiens	504	244	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CALCOCO1|SKICH|Zn-C2H2_12	PF07888|PF17751|PF18112	-	-	-	-	-
128638	220213	-	OTUD1	DUBA7|OTDC1	9606	Homo sapiens	232	4	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
116697	23062	-	GGA2	VEAR	9606	Homo sapiens	149	23	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Alpha_adaptinC2|GAT|GGA_N-GAT|VHS	PF02883|PF03127|PF18308|PF00790	-	-	-	-	-
116690	23053	-	ZSWIM8	KIAA0913	9606	Homo sapiens	95	45	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
114400	8881	RP11-569D9.4	CDC16	ANAPC6|APC6|CUT9	9606	Homo sapiens	520	254	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
125738	121551	-	BTBD11	ABTB2B	9606	Homo sapiens	10	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|Ank_2|BTB	PF00023|PF12796|PF00651	-	-	-	-	-
125468	116064	-	LRRC58	-	9606	Homo sapiens	22	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_8	PF13855	-	-	-	-	-
33189	852822	YGL058W	RAD6	PSO8|UBC2|E2 ubiquitin-conjugating protein RAD6|L000001560	559292	Saccharomyces cerevisiae (S288c)	780	1	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
125395	114907	-	FBXO32	Fbx32|MAFbx	9606	Homo sapiens	276	18	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
125465	115992	-	RNF166	-	9606	Homo sapiens	166	25	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-Di19|zf_C2HC_14	PF05605|PF18574	-	-	-	-	-
36007	855927	YPL176C	TRE1	-	559292	Saccharomyces cerevisiae (S288c)	56	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TFR_dimer	PF04253	-	-	-	-	-
128708	221302	RP3-412I7.3	ZUFSP	C6orf113|dJ412I7.3	9606	Homo sapiens	200	143	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C78	PF07910	-	-	-	-	-
125087	94015	-	TTYH2	C17orf29	9606	Homo sapiens	39	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Tweety	PF04906	-	-	-	-	-
125266	113878	-	DTX2	RNF58	9606	Homo sapiens	415	101	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DTC|WWE|zf-C3HC4	PF18102|PF02825|PF00097	-	-	-	-	-
122834	79718	-	TBL1XR1	C21|DC42|IRA1|TBLR1	9606	Homo sapiens	308	85	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LisH|WD40	PF08513|PF00400	-	-	-	-	-
123541	81603	RP11-47A8.4	TRIM8	GERP|RNF27	9606	Homo sapiens	128	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
113422	7597	-	ZBTB25	C14orf51|KUP|ZNF46	9606	Homo sapiens	79	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
34959	854781	YIL030C	SSM4	DOA10|KIS3|E3 ubiquitin-protein ligase SSM4|L000002087	559292	Saccharomyces cerevisiae (S288c)	381	19	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	96	26	11	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	KA1|Pkinase|UBA	PF02149|PF00069|PF00627	-	-	-	-	-
939065	100287404	-	USP17L19	-	9606	Homo sapiens	5	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
36174	856104	YPL003W	ULA1	ENR2|L000004374	559292	Saccharomyces cerevisiae (S288c)	167	0	0	BIOGRID	NEDD8 E1	-	-	-	-	-	-	-	-	-	-	-	-	-
123941	84196	-	USP48	RAP1GA1|USP31	9606	Homo sapiens	256	308	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
123945	84206	-	MEX3B	MEX-3B|RKHD3|RNF195	9606	Homo sapiens	240	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	KH_1	PF00013	-	-	-	-	-
121614	57559	-	STAMBPL1	ALMalpha|AMSH-FP|AMSH-LP|bA399O19.2	9606	Homo sapiens	115	7	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|USP8_dimer	PF01398|PF08969	-	-	-	-	-
121616	57561	-	ARRDC3	TLIMP	9606	Homo sapiens	290	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
121613	57558	-	USP35	-	9606	Homo sapiens	77	4	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
107603	1191	AAG4	CLU	APO-J|APOJ|CLI|CLU1|CLU2|KUB1|NA1/NA2|SGP-2|SGP2|SP-40|TRPM-2|TRPM2	9606	Homo sapiens	435	9	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Clusterin	PF01093	-	-	-	-	-
121619	57565	-	KLHL14	-	9606	Homo sapiens	97	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121618	57563	-	KLHL8	-	9606	Homo sapiens	138	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	270	50	43	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GTPase_binding|Inhibitor_Mig-6|PK_Tyr_Ser-Thr|SH3_9	PF09027|PF11555|PF07714|PF14604	-	-	-	-	-
33235	852873	YGL011C	SCL1	PRC2|proteasome core particle subunit alpha 1|L000001812	559292	Saccharomyces cerevisiae (S288c)	640	8	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
119331	51147	My036	ING4	p29ING4	9606	Homo sapiens	162	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ING	PF12998	-	-	-	-	-
107116	648	RP11-573G6.1	BMI1	FLVI2/BMI1|PCGF4|RNF51	9606	Homo sapiens	1027	8	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
122237	64708	-	COPS7B	CSN7B|SGN7b	9606	Homo sapiens	313	54	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	CSN7a_helixI|PCI	PF18392|PF01399	-	-	-	-	-
126065	127544	-	RNF19B	IBRDC3|NKLAM	9606	Homo sapiens	129	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
110811	4734	PIG53	NEDD4	NEDD4-1|RPF1	9606	Homo sapiens	1176	124	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|WW	PF00632|PF00397	-	-	-	-	-
31584	851030	YLR320W	MMS22	SLM2	559292	Saccharomyces cerevisiae (S288c)	1523	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Mus7	PF09462	-	-	-	-	-
31586	851033	YLR323C	CWC24	-	559292	Saccharomyces cerevisiae (S288c)	352	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CCCH	PF00642	-	-	-	-	-
31210	850613	YFR052W	RPN12	NIN1|proteasome regulatory particle lid subunit RPN12|L000001251	559292	Saccharomyces cerevisiae (S288c)	948	4	0	BIOGRID	Proteasome	-	-	-	-	-	-	CSN8_PSD8_EIF3K	PF10075	-	-	-	-	-
31215	850620	YLL039C	UBI4	SCD2|UB14|ubiquitin|L000002414	559292	Saccharomyces cerevisiae (S288c)	1270	38	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
31217	850623	YLL036C	PRP19	PSO4|E3 ubiquitin-protein ligase PRP19|L000001506	559292	Saccharomyces cerevisiae (S288c)	825	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Prp19	PF08606	-	-	-	-	-
114203	8651	-	SOCS1	CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP3	9606	Homo sapiens	340	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2	PF00017	-	-	-	-	-
126719	140825	-	NEURL2	C20orf163|OZZ|OZZ-E3	9606	Homo sapiens	10	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Neuralized|SOCS_box	PF07177|PF07525	-	-	-	-	-
32041	851549	YDL013W	SLX5	HEX3|ULS2|SUMO-targeted ubiquitin ligase complex subunit SLX5|L000000768	559292	Saccharomyces cerevisiae (S288c)	1376	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
126246	130617	-	ZFAND2B	AIRAPL	9606	Homo sapiens	91	34	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	zf-AN1	PF01428	-	-	-	-	-
35046	854876	YML097C	VPS9	VPL31|VPT9|guanine nucleotide exchange factor VPS9|L000002659	559292	Saccharomyces cerevisiae (S288c)	989	14	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE|DUF5601|VPS9	PF02845|PF18151|PF02204	-	-	-	-	-
35042	854871	YML101C	CUE4	-	559292	Saccharomyces cerevisiae (S288c)	127	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
110815	4738	-	NEDD8	NEDD-8	9606	Homo sapiens	568	12	0	BIOGRID	NEDD8	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
34533	854306	YOR138C	RUP1	-	559292	Saccharomyces cerevisiae (S288c)	115	11	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA	PF00627	-	-	-	-	-
132073	378884	-	NHLRC1	EPM2A|EPM2B|MALIN|bA204B7.2	9606	Homo sapiens	61	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_5	PF14634	-	-	-	-	-
132076	378925	-	RNF148	-	9606	Homo sapiens	56	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
119029	30011	RP11-345L8.1	SH3KBP1	CD2BP3|CIN85|GIG10|HSB-1|HSB1|MIG18	9606	Homo sapiens	659	57	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SH3_9	PF14604	-	-	-	-	-
108209	1877	-	E4F1	E4F	9606	Homo sapiens	170	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C2H2	PF00096	-	-	-	-	-
107076	604	-	BCL6	BCL5|BCL6A|LAZ3|ZBTB27|ZNF51	9606	Homo sapiens	354	15	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
31103	850500	YFL044C	OTU1	YOD1	559292	Saccharomyces cerevisiae (S288c)	152	6	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
111786	5828	-	PEX2	PAF1|PBD5A|PBD5B|PMP3|PMP35|PXMP3|RNF72|ZWS3	9606	Homo sapiens	23	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12|zf-C3HC4	PF04757|PF00097	-	-	-	-	-
117647	26261	-	FBXO24	FBX24	9606	Homo sapiens	21	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|RCC1	PF12937|PF00415	-	-	-	-	-
117646	26260	-	FBXO25	FBX25	9606	Homo sapiens	220	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117645	26259	-	FBXW8	FBW6|FBW8|FBX29|FBXO29|FBXW6	9606	Homo sapiens	243	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
127283	150350	RP1-172B20.3	ENTHD1	CACNA1I|dJ370M22.3	9606	Homo sapiens	56	0	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH	PF01417	-	-	-	-	-
32485	852037	YDR427W	RPN9	NAS7|proteasome regulatory particle lid subunit RPN9|L000004309	559292	Saccharomyces cerevisiae (S288c)	302	5	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|Rpn9_C	PF01399|PF18261	-	-	-	-	-
33073	852694	YGL181W	GTS1	FHT1|LSR1|L000000743	559292	Saccharomyces cerevisiae (S288c)	161	22	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ArfGap|UBA	PF01412|PF00627	-	-	-	-	-
117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	624	14	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|FIST_C	PF00646|PF10442	-	-	-	-	-
117648	26262	-	TSPAN17	FBX23|FBXO23|TM4SF17	9606	Homo sapiens	125	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Tetraspanin	PF00335	-	-	-	-	-
34623	854405	YOR230W	WTM1	L000003515	559292	Saccharomyces cerevisiae (S288c)	154	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
126801	143384	-	CACUL1	C10orf46|CAC1	9606	Homo sapiens	31	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin	PF00888	-	-	-	-	-
135086	401447	-	USP17L1	USP17L1P	9606	Homo sapiens	6	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
126804	143471	-	PSMA8	PSMA7L	9606	Homo sapiens	125	29	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
115869	10625	RP4-635A23.5	IVNS1ABP	FLARA3|HSPC068|KLHL39|ND1|NS-1|NS1-BP|NS1BP	9606	Homo sapiens	194	28	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
115863	10617	-	STAMBP	AMSH|MICCAP	9606	Homo sapiens	263	166	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|USP8_dimer	PF01398|PF08969	-	-	-	-	-
115862	10616	RP5-852M4.4	RBCK1	C20orf18|HOIL-1|HOIL1|PBMEI|RBCK2|RNF54|UBCE7IP3|XAP3|XAP4|ZRANB4	9606	Homo sapiens	789	46	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR|zf-RING_UBOX	PF01485|PF13445	-	-	-	-	-
32809	852402	YBR105C	VID24	GID4|glucose-induced degradation complex subunit VID24|L000004624	559292	Saccharomyces cerevisiae (S288c)	482	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Vac_ImportDeg	PF09783	-	-	-	-	-
109861	3652	RP11-767N6.6	IPP	KLHL27	9606	Homo sapiens	52	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
116910	23321	-	TRIM2	CMT2R|RNF86	9606	Homo sapiens	84	181	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Filamin|NHL|zf-B_box|zf-RING_UBOX	PF00630|PF01436|PF00643|PF13445	-	-	-	-	-
117477	26001	LP2254	RNF167	5730408C10Rik|RING105	9606	Homo sapiens	116	147	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
116914	23326	-	USP22	USP3L	9606	Homo sapiens	366	39	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
116915	23327	-	NEDD4L	NEDD4-2|NEDD4.2|RSP5|hNEDD4-2	9606	Homo sapiens	684	385	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
117573	26137	RP11-553L6.5	ZBTB20	DPZF|HOF|ODA-8S|PRIMS|ZNF288	9606	Homo sapiens	58	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
31969	851467	YDL091C	UBX3	-	559292	Saccharomyces cerevisiae (S288c)	200	1	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)	-	-	-	-	-	-	UBX	PF00789	-	-	-	-	-
115910	10668	-	CGRRF1	CGR19|RNF197	9606	Homo sapiens	147	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
113779	8110	-	DPF3	BAF45C|CERD4	9606	Homo sapiens	214	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|Requiem_N	PF00628|PF14051	-	-	-	-	-
31965	851461	YDL097C	RPN6	NAS4|proteasome regulatory particle lid subunit RPN6|L000004306	559292	Saccharomyces cerevisiae (S288c)	1156	20	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|RPN6_C_helix|RPN6_N	PF01399|PF18503|PF18055	-	-	-	-	-
130781	338692	-	ANKRD13D	-	9606	Homo sapiens	105	30	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GPCR_chapero_1	PF11904	-	-	-	-	-
126622	140545	tcag7.575	RNF32	FKSG33|HSD15|LMBR2	9606	Homo sapiens	52	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IQ|zf-RING_2|zf-RING_UBOX	PF00612|PF13639|PF13445	-	-	-	-	-
124639	89890	-	KBTBD6	-	9606	Homo sapiens	192	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
31937	851431	YDL126C	CDC48	AAA family ATPase CDC48|L000000280	559292	Saccharomyces cerevisiae (S288c)	2501	47	0	BIOGRID	ER-associated degradation (ERAD)|Endosome and golgi-associated degradation (EGAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	AAA|AAA_lid_3|CDC48_2|CDC48_N|Vps4_C	PF00004|PF17862|PF02933|PF02359|PF09336	-	-	-	-	-
116596	22937	PSEC0227	SCAP	-	9606	Homo sapiens	199	29	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sterol-sensing|WD40	PF12349|PF00400	-	-	-	-	-
119545	51444	HSD4	RNF138	HSD-4|NARF|STRIN|hNARF	9606	Homo sapiens	148	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-Di19|zf_C2HC_14	PF05605|PF18574	-	-	-	-	-
118100	27252	RP3-383J4.3	KLHL20	KHLHX|KLEIP|KLHLX	9606	Homo sapiens	339	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
608813	728386	-	USP17L5	-	9606	Homo sapiens	4	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
114731	9320	-	TRIP12	TRIP-12|ULF	9606	Homo sapiens	346	1534	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
120153	54793	-	KCTD9	BTBD27	9606	Homo sapiens	272	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|KHA|Pentapeptide	PF02214|PF11834|PF00805	-	-	-	-	-
124128	84541	-	KBTBD8	TA-KRP	9606	Homo sapiens	54	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120159	54800	-	KLHL24	DRE1|KRIP6	9606	Homo sapiens	90	83	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121971	63891	FP1477	RNF123	KPC1	9606	Homo sapiens	886	51	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
121973	63893	-	UBE2O	E2-230K	9606	Homo sapiens	1033	141	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	314	5	11	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DCAF15_WD40	PF14939	-	-	-	-	-
120885	55768	-	NGLY1	CDG1V|PNG1|PNGase	9606	Homo sapiens	138	126	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	PAW|PUB|Transglut_core	PF04721|PF09409|PF01841	-	-	-	-	-
32114	851631	YDR059C	UBC5	E2 ubiquitin-conjugating protein UBC5|L000002408	559292	Saccharomyces cerevisiae (S288c)	122	2	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
116775	23163	-	GGA3	-	9606	Homo sapiens	182	209	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Alpha_adaptinC2|GAT|GGA_N-GAT|VHS	PF02883|PF03127|PF18308|PF00790	-	-	-	-	-
32110	851627	YDR057W	YOS9	-	559292	Saccharomyces cerevisiae (S288c)	198	8	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	PRKCSH|Yos9_DD	PF07915|PF17880	-	-	-	-	-
117359	25831	-	HECTD1	EULIR	9606	Homo sapiens	1263	364	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|BTHB|HECT|MIB_HERC2|Sad1_UNC	PF12796|PF18410|PF00632|PF06701|PF07738	-	-	-	-	-
117355	25827	-	FBXL2	FBL2|FBL3	9606	Homo sapiens	87	2	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
111920	5988	-	RFPL1	RNF78	9606	Homo sapiens	18	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|RDM|SPRY	PF13765|PF11002|PF00622	-	-	-	-	-
124386	84954	-	MPND	-	9606	Homo sapiens	14	18	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|RAMA	PF01398|PF18755	-	-	-	-	-
125479	116143	-	WDR92	-	9606	Homo sapiens	236	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
125478	116138	RP1-20C7.3	KLHDC3	PEAS|dJ20C7.3	9606	Homo sapiens	174	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Kelch_2	PF07646	-	-	-	-	-
113182	7334	-	UBE2N	HEL-S-71|UBC13|UBCHBEN; UBC13|UbcH-ben|UbcH13	9606	Homo sapiens	707	13	2	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113183	7335	P/OKcl.19	UBE2V1	CIR1|CROC-1|CROC1|UBE2V|UEV-1|UEV1|UEV1A	9606	Homo sapiens	185	99	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113184	7336	-	UBE2V2	DDVIT1|DDVit-1|EDAF-1|EDPF-1|EDPF1|MMS2|UEV-2|UEV2	9606	Homo sapiens	156	22	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113185	7337	-	UBE3A	ANCR|AS|E6-AP|EPVE6AP|HPVE6A	9606	Homo sapiens	1030	1828	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	AZUL|HECT	PF16558|PF00632	-	-	-	-	-
134130	392197	-	USP17L7	-	9606	Homo sapiens	6	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
121119	56254	-	RNF20	BRE1|BRE1A|hBRE1	9606	Homo sapiens	387	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
120976	55884	-	WSB2	SBA2	9606	Homo sapiens	107	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box|WD40	PF07525|PF00400	-	-	-	-	-
124418	84993	SB132	UBL7	BMSC-UbP|TCBA1	9606	Homo sapiens	100	83	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
118941	29888	-	STRN4	ZIN|zinedin	9606	Homo sapiens	259	42	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Striatin|WD40	PF08232|PF00400	-	-	-	-	-
118946	29894	-	CPSF1	CPSF160|HSU37012|P/cl.18	9606	Homo sapiens	338	153	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CPSF_A	PF03178	-	-	-	-	-
121281	56957	RP11-212K13.2	OTUD7B	CEZANNE|ZA20D1	9606	Homo sapiens	125	126	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	OTU|zf-A20	PF02338|PF01754	-	-	-	-	-
116176	10980	-	COPS6	CSN6|MOV34-34KD	9606	Homo sapiens	772	16	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
122956	79868	RP1-298J18.2	ALG13	CDG1S|CXorf45|GLT28D1|MDS031|TDRD13|YGL047W	9606	Homo sapiens	216	90	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Glyco_tran_28_C|OTU	PF04101|PF02338	-	-	-	-	-
113520	7732	-	RNF112	BFP|ZNF179	9606	Homo sapiens	778	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	GBP|zf-C3HC4	PF02263|PF00097	-	-	-	-	-
36811	856799	YER068W	MOT2	NOT4|SIG1|CCR4-NOT core ubiquitin-protein ligase subunit MOT2|L000001887|L000001137	559292	Saccharomyces cerevisiae (S288c)	441	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
122820	79699	-	ZYG11B	ZYG11	9606	Homo sapiens	192	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121021	55975	-	KLHL7	KLHL6|SBBI26	9606	Homo sapiens	76	109	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121593	57534	-	MIB1	DIP-1|DIP1|LVNC7|MIB|ZZANK2|ZZZ6	9606	Homo sapiens	444	150	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|MIB_HERC2|SH3_15|ZZ	PF12796|PF06701|PF18346|PF00569	-	-	-	-	-
121590	57531	-	HACE1	-	9606	Homo sapiens	116	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|HECT	PF12796|PF00632	-	-	-	-	-
116001	10785	-	WDR4	TRM82|TRMT82	9606	Homo sapiens	126	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
122485	79016	-	DDA1	C19orf58|PCIA1	9606	Homo sapiens	494	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DDA1	PF10172	-	-	-	-	-
122487	79018	-	GID4	C17orf39|VID24	9606	Homo sapiens	187	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Vac_ImportDeg	PF09783	-	-	-	-	-
121218	56888	-	KCMF1	DEBT91|FIGC|PCMF|ZZZ1	9606	Homo sapiens	272	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ZZ|zf-Di19	PF00569|PF05605	-	-	-	-	-
36107	856032	YPL072W	UBP16	L000004590	559292	Saccharomyces cerevisiae (S288c)	72	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
119239	51035	-	UBXN1	2B28|SAKS1|UBXD10	9606	Homo sapiens	309	56	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|UBX	PF00627|PF00789	-	-	-	-	-
119234	51028	CGI-145	VPS36	C13orf9|EAP45	9606	Homo sapiens	112	37	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EAP30|Vps36_ESCRT-II	PF04157|PF11605	-	-	-	-	-
33554	853226	YJL204C	RCY1	-	559292	Saccharomyces cerevisiae (S288c)	269	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sec10	PF07393	-	-	-	-	-
113852	8216	-	LZTR1	BTBD29|LZTR-1|SWNTS2	9606	Homo sapiens	183	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Kelch_1|Kelch_2	PF00651|PF01344|PF07646	-	-	-	-	-
127416	152006	RP11-84P7.4	RNF38	-	9606	Homo sapiens	124	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
121627	57574	-	MARCH4	MARCH-IV|RNF174	9606	Homo sapiens	150	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
122133	64320	-	RNF25	AO7	9606	Homo sapiens	95	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RWD|zf-RING_11	PF05773|PF17123	-	-	-	-	-
122135	64324	-	NSD1	ARA267|KMT3B|SOTOS|SOTOS1|STO	9606	Homo sapiens	155	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	AWS|C5HCH|PWWP|SET	PF17907|PF17982|PF00855|PF00856	-	-	-	-	-
122136	64326	RP11-318C24.3	RFWD2	COP1|RNF200	9606	Homo sapiens	594	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
36261	856208	YPR093C	ASR1	ubiquitin-protein ligase ASR1	559292	Saccharomyces cerevisiae (S288c)	177	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
35269	855119	YMR094W	CTF13	CBF3C|L000000429	559292	Saccharomyces cerevisiae (S288c)	262	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
115457	10155	-	TRIM28	KAP1|PPP1R157|RNF96|TF1B|TIF1B	9606	Homo sapiens	2415	50	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|zf-B_box|zf-RING_5	PF00628|PF00643|PF14634	-	-	-	-	-
114986	9627	-	SNCAIP	SYPH1|Sph1	9606	Homo sapiens	89	39	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SNCAIP_SNCA_bd	PF12796|PF16700	-	-	-	-	-
33955	853670	YKL210W	UBA1	E1 ubiquitin-activating protein UBA1|L000002405	559292	Saccharomyces cerevisiae (S288c)	225	33	0	BIOGRID	Ubiquitin activating enzyme (E1)	-	-	-	-	-	-	E1_4HB|E1_FCCH|E1_UFD|ThiF|UBA_e1_thiolCys	PF16191|PF16190|PF09358|PF00899|PF10585	-	-	-	-	-
33952	853667	YKL213C	DOA1	UFD3|ZZZ4|L000002961	559292	Saccharomyces cerevisiae (S288c)	1252	17	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	PFU|PUL|WD40	PF09070|PF08324|PF00400	-	-	-	-	-
123191	80227	-	PAAF1	PAAF|Rpn14|WDR71	9606	Homo sapiens	167	41	0	BIOGRID	Proteasome	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
123193	80230	-	RUFY1	RABIP4|ZFYVE12	9606	Homo sapiens	571	74	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FYVE|RUN	PF01363|PF02759	-	-	-	-	-
123195	80232	PRO0852	WDR26	CDW2|GID7|MIP2	9606	Homo sapiens	299	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
115581	10293	-	TRAIP	RNF206|TRIP	9606	Homo sapiens	111	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
115587	10299	-	MARCH6	DOA10|MARCH-VI|RNF176|TEB4	9606	Homo sapiens	88	65	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
115584	10296	HLC10	MAEA	EMLP|EMP|GID9|HLC-10|PIG5	9606	Homo sapiens	265	134	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
116716	23087	-	TRIM35	HLS5|MAIR	9606	Homo sapiens	127	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
115588	10300	-	KATNB1	KAT	9606	Homo sapiens	102	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Katanin_con80|WD40	PF13925|PF00400	-	-	-	-	-
122229	64682	-	ANAPC1	APC1|MCPR|TSG24	9606	Homo sapiens	347	199	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC1|APC1_C	PF12859|PF18122	-	-	-	-	-
34985	854810	YIL007C	NAS2	-	559292	Saccharomyces cerevisiae (S288c)	220	2	0	BIOGRID	Proteasome	-	-	-	-	-	-	Nas2_N|PDZ	PF18265|PF00595	-	-	-	-	-
34328	854081	YOL073C	DSC2	YOL073C	559292	Saccharomyces cerevisiae (S288c)	123	3	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	552	271	10	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
118788	28962	HSPC019	OSTM1	GIPN|GL|OPTB5	9606	Homo sapiens	127	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	OSTMP1	PF09777	-	-	-	-	-
114214	8665	-	EIF3F	EIF3S5|eIF3-p47	9606	Homo sapiens	532	9	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
114216	8667	-	EIF3H	EIF3S3|eIF3-gamma|eIF3-p40	9606	Homo sapiens	531	22	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB	PF01398	-	-	-	-	-
110772	4692	-	NDN	HsT16328|PWCR	9606	Homo sapiens	450	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
35053	854886	YML088W	UFO1	SCF ubiquitin ligase complex subunit UFO1	559292	Saccharomyces cerevisiae (S288c)	249	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
35051	854882	YML092C	PRE8	proteasome core particle subunit alpha 2|L000002700	559292	Saccharomyces cerevisiae (S288c)	494	14	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
127823	162517	-	FBXO39	CT144|Fbx39	9606	Homo sapiens	4	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
107047	571	-	BACH1	BACH-1|BTBD24	9606	Homo sapiens	204	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|bZIP_Maf	PF00651|PF03131	-	-	-	-	-
31175	850578	YFR022W	ROG3	ART7	559292	Saccharomyces cerevisiae (S288c)	72	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
126654	140691	hCG_39321	TRIM69	HSD-34|HSD34|RNF36|Trif	9606	Homo sapiens	137	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY	PF13765|PF00622	-	-	-	-	-
111976	6049	RP11-380N8.5	RNF6	-	9606	Homo sapiens	102	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
111975	6048	DAAP-218M18.2	RNF5	RING5|RMA1	9606	Homo sapiens	275	5	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111974	6047	RES4-26	RNF4	SLX5|SNURF	9606	Homo sapiens	1617	6	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111972	6045	GS1-120K12.1	RNF2	BAP-1|BAP1|DING|HIPI3|RING1B|RING2	9606	Homo sapiens	1341	27	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
128390	201501	-	ZBTB7C	APM-1|APM1|ZBTB36|ZNF857C	9606	Homo sapiens	43	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
117637	26249	-	KLHL3	PHA2D	9606	Homo sapiens	99	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
117982	27072	-	VPS41	HVPS41|HVSP41|hVps41p	9606	Homo sapiens	142	31	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Clathrin	PF00637	-	-	-	-	-
130425	287015	-	TRIM42	PPP1R40	9606	Homo sapiens	158	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	fn3|zf-B_box	PF00041|PF00643	-	-	-	-	-
126500	138065	-	RNF183	-	9606	Homo sapiens	61	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
32471	852020	YDR411C	DFM1	-	559292	Saccharomyces cerevisiae (S288c)	134	2	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	DER1	PF04511	-	-	-	-	-
130421	286827	-	TRIM59	MRF1|RNF104|TRIM57|TSBF1	9606	Homo sapiens	108	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
34617	854398	YOR223W	DSC3	YOR223W	559292	Saccharomyces cerevisiae (S288c)	98	2	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)	-	-	-	-	-	-	DUF2407|DUF2407_C	PF10302|PF13373	-	-	-	-	-
115853	10607	-	TBL3	SAZD|UTP13	9606	Homo sapiens	259	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Utp13|WD40	PF08625|PF00400	-	-	-	-	-
114504	9040	-	UBE2M	UBC-RS2|UBC12|hUbc12	9606	Homo sapiens	888	20	0	BIOGRID	NEDD8 E2	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
115858	10612	-	TRIM3	BERP|HAC1|RNF22|RNF97	9606	Homo sapiens	119	28	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Filamin|NHL|zf-B_box|zf-RING_UBOX	PF00630|PF01436|PF00643|PF13445	-	-	-	-	-
114503	9039	-	UBA3	NAE2|UBE1C|hUBA3	9606	Homo sapiens	152	71	1	BIOGRID	NEDD8 E1	-	-	-	-	-	-	E2_bind|ThiF	PF08825|PF00899	-	-	-	-	-
132681	388419	-	BTBD17	BTBD17A|LGALS3BPL|TANGO10A	9606	Homo sapiens	7	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB	PF07707|PF00651	-	-	-	-	-
32870	852468	YBR170C	NPL4	HRD4|L000001271	559292	Saccharomyces cerevisiae (S288c)	385	12	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	NPL4|zf-NPL4	PF05021|PF05020	-	-	-	-	-
32873	852471	YBR173C	UMP1	RNS2|L000004429	559292	Saccharomyces cerevisiae (S288c)	422	0	0	BIOGRID	Proteasome	-	-	-	-	-	-	UMP1	PF05348	-	-	-	-	-
30973	850349	YCL008C	STP22	AGS1|VPL15|VPS23|ubiquitin-binding ESCRT-I subunit protein STP22|L000003975|S000029031|L000000064	559292	Saccharomyces cerevisiae (S288c)	585	1	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UEV|Vps23_core	PF05743|PF09454	-	-	-	-	-
131797	359948	-	IRF2BP2	-	9606	Homo sapiens	172	31	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IRF-2BP1_2	PF11261	-	-	-	-	-
31398	850820	YLR129W	DIP2	UTP12|L000003088	559292	Saccharomyces cerevisiae (S288c)	262	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Utp12|WD40	PF04003|PF00400	-	-	-	-	-
131885	373856	-	USP41	-	9606	Homo sapiens	15	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
131884	373509	-	USP50	-	9606	Homo sapiens	48	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
31397	850819	YLR128W	DCN1	NEDD8 ligase DCN1	559292	Saccharomyces cerevisiae (S288c)	71	2	0	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
31396	850818	YLR127C	APC2	RSI1|TID2|anaphase promoting complex subunit 2|L000003970|L000004348	559292	Saccharomyces cerevisiae (S288c)	259	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC2|Cullin	PF08672|PF00888	-	-	-	-	-
110427	4281	RP11-120D5.1	MID1	BBBG1|FXY|GBBB1|MIDIN|OGS1|OS|OSX|RNF59|TRIM18|XPRF|ZNFXY	9606	Homo sapiens	278	117	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	COS|PRY|SPRY|fn3|zf-B_box|zf-RING_UBOX	PF18568|PF13765|PF00622|PF00041|PF00643|PF13445	-	-	-	-	-
608846	728419	-	USP17L30	-	9606	Homo sapiens	0	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
120369	55040	-	EPN3	-	9606	Homo sapiens	105	4	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH|UIM	PF01417|PF02809	-	-	-	-	-
110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	2752	95	103	BIOGRID	NEDD8 E3|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SWIB|zf-RanBP	PF02201|PF00641	-	-	-	-	-
110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	419	29	7	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SWIB|zf-RanBP	PF02201|PF00641	-	-	-	-	-
120360	55031	-	USP47	TRFP	9606	Homo sapiens	291	222	5	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
35674	855567	YNL155W	CUZ1	-	559292	Saccharomyces cerevisiae (S288c)	149	2	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	zf-AN1	PF01428	-	-	-	-	-
131531	348793	-	WDR53	-	9606	Homo sapiens	34	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40	PF12894|PF00400	-	-	-	-	-
110193	4008	RP11-332E3.2	LMO7	FBX20|FBXO20|LOMP	9606	Homo sapiens	260	148	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CH|DUF4757|LIM|PDZ	PF00307|PF15949|PF00412|PF00595	-	-	-	-	-
35670	855563	YNL159C	ASI2	-	559292	Saccharomyces cerevisiae (S288c)	218	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
118169	27436	-	EML4	C2orf2|ELP120|EMAP-4|EMAPL4|ROPP120	9606	Homo sapiens	197	56	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HELP|WD40	PF03451|PF00400	-	-	-	-	-
3195539	102724428	-	LOC102724428	-	9606	Homo sapiens	6	31	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
115920	10681	-	GNB5	GB5	9606	Homo sapiens	94	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
114438	8924	-	HERC2	D15F37S1|MRT38|SHEP1|jdf2|p528	9606	Homo sapiens	711	208	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10|Cul7|Cyt-b5|HECT|MIB_HERC2|RCC1|ZZ	PF03256|PF11515|PF00173|PF00632|PF06701|PF00415|PF00569	-	-	-	-	-
120765	55626	-	AMBRA1	DCAF3|WDR94	9606	Homo sapiens	462	60	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
114430	8916	-	HERC3	-	9606	Homo sapiens	103	86	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|RCC1	PF00632|PF00415	-	-	-	-	-
124794	91107	-	TRIM47	GOA|RNF100	9606	Homo sapiens	83	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box	PF00643	-	-	-	-	-
32272	851805	YDR219C	MFB1	-	559292	Saccharomyces cerevisiae (S288c)	122	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
120509	55213	RP11-185C18.1	RCBTB1	CLLD7|CLLL7|GLP	9606	Homo sapiens	36	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|RCC1	PF00651|PF00415	-	-	-	-	-
116347	11177	HSPC317	BAZ1A	ACF1|WALp1|WCRF180|hACF1	9606	Homo sapiens	216	105	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|DDT|PHD|WAC_Acf1_DNA_bd|WHIM1|WSD	PF00439|PF02791|PF00628|PF10537|PF15612|PF15613	-	-	-	-	-
120504	55208	RP11-102K13.4	DCUN1D2	C13orf17	9606	Homo sapiens	69	1	1	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
119551	51455	-	REV1	REV1L	9606	Homo sapiens	97	19	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	BRCT_2|IMS|IMS_C|REV1_C|UBM	PF16589|PF00817|PF11799|PF16727|PF14377	-	-	-	-	-
117569	26133	-	TRPC4AP	C20orf188|PPP1R158|TRRP4AP|TRUSS	9606	Homo sapiens	166	129	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF3689	PF12463	-	-	-	-	-
119555	51465	CGI-76	UBE2J1	HSPC153|HSPC205|HSU93243|NCUBE-1|NCUBE1|UBC6|Ubc6p	9606	Homo sapiens	294	15	1	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
117560	26118	-	WSB1	SWIP1|WSB-1	9606	Homo sapiens	172	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box|WD40	PF07525|PF00400	-	-	-	-	-
114724	9312	-	KCNB2	KV2.2	9606	Homo sapiens	69	11	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans|Kv2channel	PF02214|PF00520|PF03521	-	-	-	-	-
119828	54014	-	BRWD1	C21orf107|N143|WDR9	9606	Homo sapiens	62	30	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|WD40	PF00439|PF00400	-	-	-	-	-
31829	851310	YDL216C	RRI1	CSN5|JAB1|S000007574	559292	Saccharomyces cerevisiae (S288c)	258	1	0	BIOGRID	Deubiquitinating enzyme (DUB)|NEDD8-specific protease	-	-	-	-	-	-	JAB	PF01398	-	-	-	-	-
114729	9318	-	COPS2	ALIEN|CSN2|SGN2|TRIP15	9606	Homo sapiens	583	34	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	PCI	PF01399	-	-	-	-	-
127521	153830	-	RNF145	-	9606	Homo sapiens	46	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TRC8_N|zf-RING_2	PF13705|PF13639	-	-	-	-	-
124243	84759	-	PCGF1	2010002K04Rik|NSPC1|RNF3A-2|RNF68	9606	Homo sapiens	369	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	36	25	4	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
124248	84767	-	TRIM51	SPRYD5|TRIM51A	9606	Homo sapiens	6	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
117367	25841	RP1-53C18.4	ABTB2	ABTB2A|BTBD22	9606	Homo sapiens	150	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|Ank_2|BTB	PF00023|PF12796|PF00651	-	-	-	-	-
32124	851641	YDR069C	DOA4	DOS1|MUT4|NPI2|SSV7|UBP4|L000000514	559292	Saccharomyces cerevisiae (S288c)	389	6	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Rhodanese|UCH	PF00581|PF00443	-	-	-	-	-
121365	57097	-	PARP11	ARTD11|C12orf6|MIB006	9606	Homo sapiens	25	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	PARP|WWE	PF00644|PF02825	-	-	-	-	-
121361	57093	-	TRIM49	RNF18|TRIM49A|TRIM49L2	9606	Homo sapiens	48	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
127540	154214	RP1-84N20.1	RNF217	C6orf172|IBRDC1|dJ84N20.1	9606	Homo sapiens	22	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
124392	84961	RP11-690G19.3	FBXL20	Fbl2|Fbl20	9606	Homo sapiens	41	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
124390	84959	-	UBASH3B	STS-1|STS1|TULA-2|TULA2|p70	9606	Homo sapiens	213	37	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	His_Phos_1|SH3_9|UBA	PF00300|PF14604|PF00627	-	-	-	-	-
128386	201456	-	FBXO15	FBX15	9606	Homo sapiens	21	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
128382	201292	-	TRIM65	4732463G12Rik	9606	Homo sapiens	109	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box|zf-C3HC4	PF00622|PF00643|PF00097	-	-	-	-	-
124626	89870	DAAP-200B17.1	TRIM15	RNF93|ZNF178|ZNFB7	9606	Homo sapiens	71	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box|zf-C3HC4	PF13765|PF00622|PF00643|PF00097	-	-	-	-	-
119958	54442	-	KCTD5	-	9606	Homo sapiens	222	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	1593	39	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40	PF12894|PF00400	-	-	-	-	-
119488	51341	-	ZBTB7A	FBI-1|FBI1|LRF|ZBTB7|ZNF857A|pokemon	9606	Homo sapiens	205	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
122728	79585	-	CORO7	0610011B16Rik|CRN7|POD1	9606	Homo sapiens	92	59	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF1899|WD40	PF08953|PF00400	-	-	-	-	-
129022	254225	-	RNF169	-	9606	Homo sapiens	119	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
122726	79582	-	SPAG16	PF20|WDR29	9606	Homo sapiens	8	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
113194	7347	RP11-173B14.3	UCHL3	UCH-L3	9606	Homo sapiens	251	19	4	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C12	PF01088	-	-	-	-	-
113192	7345	-	UCHL1	HEL-117|NDGOA|PARK5|PGP 9.5|PGP9.5|PGP95|Uch-L1	9606	Homo sapiens	378	19	10	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C12	PF01088	-	-	-	-	-
113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	1789	201	27	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	MATH|UCH|USP7_C2|USP7_ICP0_bdg	PF00917|PF00443|PF14533|PF12436	-	-	-	-	-
120982	55892	SBBIZ1	MYNN	OSZF|ZBTB31|ZNF902	9606	Homo sapiens	14	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
116165	10966	-	RAB40B	RAR|SEC4L	9606	Homo sapiens	66	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ras|SOCS_box	PF00071|PF07525	-	-	-	-	-
571579	646754	-	TRIM64C	-	9606	Homo sapiens	3	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
122927	79836	RP13-347D8.4	LONRF3	RNF127	9606	Homo sapiens	27	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LON_substr_bdg	PF02190	-	-	-	-	-
128090	170850	-	KCNG3	KV10.1|KV6.3	9606	Homo sapiens	15	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
123521	81557	RP11-363G10.1	MAGED4B	-	9606	Homo sapiens	29	59	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
123523	81559	-	TRIM11	BIA1|RNF92	9606	Homo sapiens	293	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
33726	853418	YJL034W	KAR2	GRP78|Hsp70 family ATPase KAR2|BIP|L000000887	559292	Saccharomyces cerevisiae (S288c)	947	22	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	HSP70	PF00012	-	-	-	-	-
608552	728116	RP1-27O5.1	ZBTB8B	ZNF916B	9606	Homo sapiens	17	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
125280	114088	-	TRIM9	RNF91|SPRING	9606	Homo sapiens	460	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|fn3|zf-B_box	PF00622|PF00041|PF00643	-	-	-	-	-
36599	856570	YHR165C	PRP8	DBF3|DNA39|RNA8|SLT21|USA2|U4/U6-U5 snRNP complex component PRP8|L000001500|L000003226	559292	Saccharomyces cerevisiae (S288c)	540	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	PRO8NT|PROCN|PROCT|PRP8_domainIV|RRM_4|U5_2-snRNA_bdg|U6-snRNA_bdg	PF08082|PF08083|PF08084|PF12134|PF10598|PF10597|PF10596	-	-	-	-	-
121035	56062	-	KLHL4	DKELCHL|KHL4	9606	Homo sapiens	48	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121034	56061	-	UBFD1	UBPH	9606	Homo sapiens	81	75	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
32341	851882	YDR288W	NSE3	-	559292	Saccharomyces cerevisiae (S288c)	533	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
121587	57528	-	KCTD16	-	9606	Homo sapiens	23	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
570456	645432	-	ARRDC5	-	9606	Homo sapiens	43	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
121581	57520	-	HECW2	NEDL2	9606	Homo sapiens	365	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|HECW1_helix|HECW_N|WW	PF00168|PF00632|PF18436|PF16562|PF00397	-	-	-	-	-
121582	57521	-	RPTOR	KOG1|Mip1	9606	Homo sapiens	687	48	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HEAT|Raptor_N|WD40	PF02985|PF14538|PF00400	-	-	-	-	-
33120	852746	YGL131C	SNT2	DNA-binding E3 ubiquitin-protein ligase SNT2	559292	Saccharomyces cerevisiae (S288c)	68	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BAH|PHD	PF01426|PF00628	-	-	-	-	-
33436	853096	YGR184C	UBR1	PTR1|E3 ubiquitin-protein ligase UBR1|L000002420	559292	Saccharomyces cerevisiae (S288c)	434	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRT6_C|zf-UBR	PF18995|PF02207	-	-	-	-	-
133302	389856	-	USP27X	USP22L|USP27	9606	Homo sapiens	370	4	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
33548	853219	YJL210W	PEX2	CRT1|PAS5|ubiquitin-protein ligase peroxin 2|L000000422|L000003076	559292	Saccharomyces cerevisiae (S288c)	178	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12	PF04757	-	-	-	-	-
123296	80762	PSEC0192	NDFIP1	N4WBP5	9606	Homo sapiens	184	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF2370	PF10176	-	-	-	-	-
122101	64207	My039	IRF2BPL	C14orf4|EAP1	9606	Homo sapiens	102	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IRF-2BP1_2	PF11261	-	-	-	-	-
123989	84262	-	PSMG3	C7orf48|PAC3	9606	Homo sapiens	182	13	0	BIOGRID	Proteasome	-	-	-	-	-	-	PAC3	PF10178	-	-	-	-	-
123988	84261	-	FBXW9	Fbw9	9606	Homo sapiens	42	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
123986	84259	RP11-690D19.3	DCUN1D5	-	9606	Homo sapiens	134	28	0	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
122109	64219	RP13-55H22.1	PJA1	PRAJA1|RNF70	9606	Homo sapiens	187	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
115665	10393	-	ANAPC10	APC10|DOC1	9606	Homo sapiens	146	81	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10	PF03256	-	-	-	-	-
113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	817	82	17	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|MATH	PF00651|PF00917	-	-	-	-	-
36600	856571	YHR166C	CDC23	anaphase promoting complex subunit CDC23|L000000261	559292	Saccharomyces cerevisiae (S288c)	903	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC8|TPR_8	PF04049|PF13181	-	-	-	-	-
125673	120146	-	TRIM64	C11orf28|TRIM64A	9606	Homo sapiens	11	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-C3HC4	PF00622|PF00097	-	-	-	-	-
608797	728369	-	USP17L24	-	9606	Homo sapiens	4	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
119317	51130	-	ASB3	ASB-3	9606	Homo sapiens	123	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|Ank_3|SOCS_box	PF12796|PF13606|PF07525	-	-	-	-	-
119314	51127	RP5-915N17.1	TRIM17	RBCC|RNF16|terf	9606	Homo sapiens	114	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box|zf-RING_UBOX	PF00622|PF00643|PF13445	-	-	-	-	-
119319	51132	CTD-2530H13.3	RLIM	NY-REN-43|RNF12	9606	Homo sapiens	491	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
112480	6596	-	HLTF	HIP116|HIP116A|HLTF1|RNF80|SMARCA3|SNF2L3|ZBU1	9606	Homo sapiens	226	304	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HIRAN|Helicase_C|SNF2_N	PF08797|PF00271|PF00176	-	-	-	-	-
34338	854091	YOL063C	CRT10	HUS1	559292	Saccharomyces cerevisiae (S288c)	76	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CRT10	PF08728	-	-	-	-	-
115060	9709	-	HERPUD1	HERP|Mif1|SUP	9606	Homo sapiens	230	12	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
36744	856731	YER012W	PRE1	proteasome core particle subunit beta 4|L000001483	559292	Saccharomyces cerevisiae (S288c)	716	7	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
34991	854816	YIL001W	YIL001W	-	559292	Saccharomyces cerevisiae (S288c)	29	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
34513	854284	YOR117W	RPT5	YTA1|proteasome regulatory particle base subunit RPT5|L000002555	559292	Saccharomyces cerevisiae (S288c)	1154	25	0	BIOGRID	ER-associated degradation (ERAD)|Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
34043	853772	YKL090W	CUE2	-	559292	Saccharomyces cerevisiae (S288c)	39	4	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
34519	854291	YOR124C	UBP2	L000002416	559292	Saccharomyces cerevisiae (S288c)	257	14	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	RPT|UCH	PF13446|PF00443	-	-	-	-	-
107056	580	-	BARD1	-	9606	Homo sapiens	634	56	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|zf-RING_6	PF12796|PF14835	-	-	-	-	-
119007	29979	-	UBQLN1	DA41|DSK2|PLIC-1|UBQN|XDRP1	9606	Homo sapiens	672	31	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|ubiquitin	PF00627|PF00240	-	-	-	-	-
119006	29978	HRIHFB2157	UBQLN2	ALS15|CHAP1|DSK2|N4BP4|PLIC2	9606	Homo sapiens	991	11	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|ubiquitin	PF00627|PF00240	-	-	-	-	-
31491	850921	YLR224W	YLR224W	-	559292	Saccharomyces cerevisiae (S288c)	159	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
129565	283450	-	HECTD4	C12orf51|POTAGE	9606	Homo sapiens	54	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
111666	5693	-	PSMB5	LMPX|MB1|X	9606	Homo sapiens	516	13	65	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
122841	79726	FP977	WDR59	-	9606	Homo sapiens	200	18	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
31160	850562	YFR010W	UBP6	L000004586	559292	Saccharomyces cerevisiae (S288c)	1219	35	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
111909	5977	-	DPF2	REQ|UBID4|ubi-d4	9606	Homo sapiens	515	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|Requiem_N	PF00628|PF14051	-	-	-	-	-
34422	854183	YOR018W	ROD1	ART4|L000003079	559292	Saccharomyces cerevisiae (S288c)	182	43	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
115285	9960	-	USP3	SIH003|UBP	9606	Homo sapiens	114	67	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	718	113	4	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|UCH|USP7_C2|Ubiquitin_3	PF06337|PF00443|PF14533|PF14836	-	-	-	-	-
114089	8517	-	IKBKG	AMCBX1|FIP-3|FIP3|Fip3p|IKK-gamma|IMD33|IP|IP1|IP2|IPD2|NEMO|ZC2HC9	9606	Homo sapiens	1166	127	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CC2-LZ|NEMO	PF16516|PF11577	-	-	-	-	-
117623	26232	-	FBXO2	FBG1|FBX2|Fbs1|NFB42|OCP1	9606	Homo sapiens	534	2	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|FBA	PF12937|PF04300	-	-	-	-	-
117622	26231	-	LRRC29	FBL9|FBXL9	9606	Homo sapiens	41	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_1|LRR_6	PF00560|PF13516	-	-	-	-	-
117625	26234	-	FBXL5	FBL4|FBL5|FLR1	9606	Homo sapiens	133	89	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|Hemerythrin|LRR_6	PF12937|PF01814|PF13516	-	-	-	-	-
117624	26233	-	FBXL6	FBL6|FBL6A|PP14630	9606	Homo sapiens	664	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
117626	26235	-	FBXL4	FBL4|FBL5|MTDPS13	9606	Homo sapiens	186	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
117998	27097	RP4-613A2.4	TAF5L	PAF65B	9606	Homo sapiens	185	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TFIID_NTD2|WD40	PF04494|PF00400	-	-	-	-	-
130923	339745	-	SPOPL	BTBD33	9606	Homo sapiens	19	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|MATH	PF00651|PF00917	-	-	-	-	-
127517	153769	-	SH3RF2	HEPP1|POSHER|PPP1R39|RNF158	9606	Homo sapiens	73	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH3_1|SH3_2|SH3_9|zf-RING_UBOX	PF00018|PF07653|PF14604|PF13445	-	-	-	-	-
115842	10594	-	PRPF8	HPRP8|PRP8|PRPC8|RP13|SNRNP220	9606	Homo sapiens	1260	99	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|PRO8NT|PROCN|PROCT|PRP8_domainIV|RRM_4|U5_2-snRNA_bdg|U6-snRNA_bdg	PF01398|PF08082|PF08083|PF08084|PF12134|PF10598|PF10597|PF10596	-	-	-	-	-
115848	10600	MSTP039	USP16	UBP-M|UBPM	9606	Homo sapiens	132	132	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
30944	850318	YCL039W	GID7	MOH2|glucose-induced degradation complex subunit GID7	559292	Saccharomyces cerevisiae (S288c)	144	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
30949	850323	YCL034W	LSB5	-	559292	Saccharomyces cerevisiae (S288c)	60	11	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
109221	2966	-	GTF2H2	BTF2|BTF2P44|T-BTF2P44|TFIIH|p44	9606	Homo sapiens	114	67	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C1_4|Ssl1	PF07975|PF04056	-	-	-	-	-
127192	149095	RP11-307C12.10-003	DCST1	-	9606	Homo sapiens	23	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DC_STAMP	PF07782	-	-	-	-	-
35803	855708	YNL023C	FAP1	L000004577	559292	Saccharomyces cerevisiae (S288c)	176	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	R3H|zf-NF-X1	PF01424|PF01422	-	-	-	-	-
31381	850798	YLR108C	YLR108C	-	559292	Saccharomyces cerevisiae (S288c)	55	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
110435	4289	-	MKLN1	TWA2	9606	Homo sapiens	212	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Kelch_1|Muskelin_N	PF01344|PF06588	-	-	-	-	-
110433	4287	RP11-529H20.5	ATXN3	AT3|ATX3|JOS|MJD|MJD1|SCA3	9606	Homo sapiens	663	51	0	BIOGRID	Deubiquitinating enzyme (DUB)|ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Josephin|UIM	PF02099|PF02809	-	-	-	-	-
32602	852173	YBL101C	ECM21	ART2|L000003896	559292	Saccharomyces cerevisiae (S288c)	148	75	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
35484	855350	YMR304W	UBP15	L000004589	559292	Saccharomyces cerevisiae (S288c)	326	12	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|USP7_C2|USP7_ICP0_bdg	PF00443|PF14533|PF12436	-	-	-	-	-
31941	851435	YDL122W	UBP1	L000002415	559292	Saccharomyces cerevisiae (S288c)	359	23	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
116298	11124	CGI-03	FAF1	HFAF1s|UBXD12|UBXN3A|hFAF1	9606	Homo sapiens	528	25	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBX	PF00789	-	-	-	-	-
35647	855535	YNL186W	UBP10	DOT4|L000004391|L000004588	559292	Saccharomyces cerevisiae (S288c)	368	5	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	155	116	6	BIOGRID	NEDD8 E1	-	-	-	-	-	-	ThiF	PF00899	-	-	-	-	-
124894	91947	-	ARRDC4	-	9606	Homo sapiens	90	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
120771	55632	-	G2E3	KIAA1333|PHF7B	9606	Homo sapiens	26	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
115939	10713	CGI-21	USP39	65K|HSPC332|SAD1|SNRNP65	9606	Homo sapiens	328	49	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
109131	2873	-	GPS1	COPS1|CSN1	9606	Homo sapiens	460	402	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	PCI|RPN7	PF01399|PF10602	-	-	-	-	-
120778	55643	-	BTBD2	-	9606	Homo sapiens	129	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|PHR	PF07707|PF00651|PF08005	-	-	-	-	-
612563	100128927	-	ZBTB42	ZNF925	9606	Homo sapiens	78	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
127606	157574	-	FBXO16	FBX16	9606	Homo sapiens	29	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
35242	855089	YMR067C	UBX4	CUI1	559292	Saccharomyces cerevisiae (S288c)	351	2	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	TUG-UBL1|UBX	PF11470|PF00789	-	-	-	-	-
32187	851709	YDR131C	YDR131C	-	559292	Saccharomyces cerevisiae (S288c)	76	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
120518	55223	RP11-131M11.1	TRIM62	DEAR1	9606	Homo sapiens	59	25	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
124097	84464	-	SLX4	BTBD12|FANCP|MUS312	9606	Homo sapiens	854	45	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Slx4	PF00651|PF09494	-	-	-	-	-
32044	851554	YDL008W	APC11	anaphase promoting complex subunit 11|L000004322	559292	Saccharomyces cerevisiae (S288c)	786	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-ANAPC11	PF12861	-	-	-	-	-
32047	851557	YDL007W	RPT2	YHS4|YTA5|proteasome regulatory particle base subunit RPT2|L000002559	559292	Saccharomyces cerevisiae (S288c)	745	39	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
116806	23197	-	FAF2	ETEA|UBXD8|UBXN3B	9606	Homo sapiens	755	34	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBX	PF00789	-	-	-	-	-
116807	23198	-	PSME4	PA200	9606	Homo sapiens	190	58	0	BIOGRID	Proteasome	-	-	-	-	-	-	BLM10_mid|DUF3437	PF16507|PF11919	-	-	-	-	-
116370	11201	-	POLI	RAD30B|RAD3OB	9606	Homo sapiens	78	224	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	IMS|IMS_C	PF00817|PF11799	-	-	-	-	-
116803	23194	-	FBXL7	FBL6|FBL7	9606	Homo sapiens	56	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
120572	55284	-	UBE2W	UBC-16|UBC16	9606	Homo sapiens	146	1	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
119564	51479	-	ANKFY1	ANKHZN|BTBD23|ZFYVE14	9606	Homo sapiens	295	74	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|Ank_2|BTB|FYVE	PF00023|PF12796|PF00651|PF01363	-	-	-	-	-
116574	22911	-	WDR47	-	9606	Homo sapiens	55	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40	PF12894|PF00400	-	-	-	-	-
116573	22909	RP11-540B6.6	FAN1	KIAA1018|KMIN|MTMR15	9606	Homo sapiens	113	8	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	VRR_NUC	PF08774	-	-	-	-	-
117576	26145	-	IRF2BP1	-	9606	Homo sapiens	127	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IRF-2BP1_2|zf-C3HC4	PF11261|PF00097	-	-	-	-	-
121913	60468	RP11-63K6.2	BACH2	BTBD25	9606	Homo sapiens	112	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|bZIP_Maf	PF00651|PF03131	-	-	-	-	-
115149	9810	-	RNF40	BRE1B|RBP95|STARING	9606	Homo sapiens	406	120	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
114719	9306	-	SOCS6	CIS-4|CIS4|HSPC060|SOCS-4|SOCS-6|SOCS4|SSI4|STAI4|STATI4	9606	Homo sapiens	236	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS_box	PF00017|PF07525	-	-	-	-	-
119540	51438	-	MAGEC2	CT10|HCA587|MAGEE1	9606	Homo sapiens	60	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116976	23403	-	FBXO46	20D7-FC4|FBXO34L|Fbx46	9606	Homo sapiens	49	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
120170	54813	-	KLHL28	BTBD5	9606	Homo sapiens	48	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120200	54850	-	FBXL12	Fbl12	9606	Homo sapiens	139	31	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
117372	25847	-	ANAPC13	APC13|SWM1	9606	Homo sapiens	131	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Apc13p	PF05839	-	-	-	-	-
117377	25853	-	DCAF12	CT102|KIAA1892|TCC52|WDR40A	9606	Homo sapiens	130	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117376	25852	S863-2	ARMC8	GID5|HSPC056|VID28	9606	Homo sapiens	394	70	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arm	PF00514	-	-	-	-	-
117379	25855	-	BRMS1	-	9606	Homo sapiens	188	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sds3	PF08598	-	-	-	-	-
120199	54849	-	DEF8	-	9606	Homo sapiens	92	250	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C1_1|zf-RING_9	PF00130|PF13901	-	-	-	-	-
114546	9092	-	SART1	Ara1|HOMS1|SART1259|SNRNP110|Snu66	9606	Homo sapiens	473	65	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SART-1	PF03343	-	-	-	-	-
124650	89970	UNQ328/PRO444	RSPRY1	-	9606	Homo sapiens	127	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
124656	90025	RP4-751H9.1	UBE3D	C6orf157|H10BH|UBE2CBP|YJR141W	9606	Homo sapiens	68	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT_2	PF09814	-	-	-	-	-
119962	54455	-	FBXO42	Fbx42|JFK	9606	Homo sapiens	319	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|Kelch_2	PF12937|PF07646	-	-	-	-	-
119967	54461	PP3971	FBXW5	Fbw5	9606	Homo sapiens	257	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
122731	79589	RP11-150F24.1	RNF128	GRAIL	9606	Homo sapiens	95	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
122736	79596	-	RNF219	C13orf7	9606	Homo sapiens	233	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
122734	79594	RP11-401M16.2	MUL1	C1orf166|GIDE|MAPL|MULAN|RNF218	9606	Homo sapiens	179	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	GIDE	PF12483	-	-	-	-	-
116156	10956	-	OS9	ERLEC2|OS-9	9606	Homo sapiens	408	210	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	PRKCSH	PF07915	-	-	-	-	-
116152	10952	-	SEC61B	-	9606	Homo sapiens	1061	5	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Sec61_beta	PF03911	-	-	-	-	-
120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	192	14	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-Di19|zf-RING_UBOX|zf_C2HC_14	PF05605|PF13445|PF18574	-	-	-	-	-
118968	29927	-	SEC61A1	HSEC61|SEC61|SEC61A	9606	Homo sapiens	318	13	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Plug_translocon|SecY	PF10559|PF00344	-	-	-	-	-
118965	29924	-	EPN1	-	9606	Homo sapiens	189	175	6	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH	PF01417	-	-	-	-	-
122933	79842	-	ZBTB3	-	9606	Homo sapiens	64	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
119582	51514	RP11-15I11.1	DTL	CDT2|DCAF2|L2DTL|RAMP	9606	Homo sapiens	271	109	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
122936	79845	-	RNF122	-	9606	Homo sapiens	24	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
113500	7706	-	TRIM25	EFP|RNF147|Z147|ZNF147	9606	Homo sapiens	2954	37	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY	PF13765|PF00622	-	-	-	-	-
113503	7709	RP1-134O19.2	ZBTB17	MIZ-1|ZNF151|ZNF60|pHZ-67	9606	Homo sapiens	113	36	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
122848	79734	RP5-1170K4.4	KCTD17	-	9606	Homo sapiens	227	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
118982	29945	-	ANAPC4	APC4	9606	Homo sapiens	450	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4|ANAPC4_WD40	PF12896|PF12894	-	-	-	-	-
123514	81550	RP11-459E2.1	TDRD3	-	9606	Homo sapiens	317	55	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	RMI1_N|TUDOR|UBA	PF08585|PF00567|PF00627	-	-	-	-	-
118988	29951	-	PDZRN4	LNX4|SAMCAP3L	9606	Homo sapiens	8	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PDZ	PF00595	-	-	-	-	-
123513	81545	SP329	FBXO38	Fbx38|HMN2D|MOKA	9606	Homo sapiens	196	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
609785	729384	-	TRIM49D2P	TRIM48L1|TRIM49D1|TRIM49L|TRIM49L1	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
121009	55958	RP11-380P16.6	KLHL9	-	9606	Homo sapiens	174	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
107581	1161	-	ERCC8	CKN1|CSA|UVSS2	9606	Homo sapiens	257	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
107582	1163	RP11-307C12.6	CKS1B	CKS1|PNAS-16|PNAS-18|ckshs1	9606	Homo sapiens	221	6	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CKS	PF01111	-	-	-	-	-
36901	856895	YER151C	UBP3	BLM3|mRNA-binding ubiquitin-specific protease UBP3|L000002417|S000086717	559292	Saccharomyces cerevisiae (S288c)	2028	52	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
125900	124930	-	ANKRD13B	-	9606	Homo sapiens	19	23	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Ank_2|GPCR_chapero_1	PF12796|PF11904	-	-	-	-	-
568114	642612	-	TRIM49C	TRIM49L2	9606	Homo sapiens	6	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
33157	852786	YGL094C	PAN2	L000003115	559292	Saccharomyces cerevisiae (S288c)	229	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	RNase_T|UCH_1	PF00929|PF13423	-	-	-	-	-
133317	389898	RP3-526F5.1	UBE2NL	Li174	9606	Homo sapiens	17	8	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
112870	7011	-	TEP1	TLP1|TP1|TROVE1|VAULT2|p240	9606	Homo sapiens	72	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF4062|NACHT|TEP1_N|TROVE|WD40	PF13271|PF05729|PF05386|PF05731|PF00400	-	-	-	-	-
938900	100287238	-	USP17L13	-	9606	Homo sapiens	3	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	329	158	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF3337|WD40	PF11816|PF00400	-	-	-	-	-
115618	10336	-	PCGF3	DONG1|RNF3|RNF3A	9606	Homo sapiens	187	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
122593	79176	RP11-18I14.1	FBXL15	FBXO37|Fbl15|JET|PSD	9606	Homo sapiens	57	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|LRR_6	PF00646|PF13516	-	-	-	-	-
36634	856607	YHR200W	RPN10	MCB1|SUN1|proteasome regulatory particle base subunit RPN10|L000003108	559292	Saccharomyces cerevisiae (S288c)	1672	4	0	BIOGRID	Proteasome|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	VWA_2	PF13519	-	-	-	-	-
36638	856611	YHR204W	MNL1	HTM1|alpha-1,2-mannosidase MNL1	559292	Saccharomyces cerevisiae (S288c)	65	1	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Glyco_hydro_47	PF01532	-	-	-	-	-
113479	7681	-	MKRN3	CPPB2|D15S9|RNF63|ZFP127|ZNF127	9606	Homo sapiens	264	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MKRN1_C|zf-C3HC4|zf-CCCH_4	PF15815|PF00097|PF18044	-	-	-	-	-
122599	79184	RP11-143H17.2	BRCC3	BRCC36|C6.1A|CXorf53	9606	Homo sapiens	282	35	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	BRCC36_C|JAB	PF18110|PF01398	-	-	-	-	-
119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	371	40	1514	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LON_substr_bdg|Yippee-Mis18	PF02190|PF03226	-	-	-	-	-
119365	51191	-	HERC5	CEB1|CEBP1	9606	Homo sapiens	324	31	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|RCC1	PF00632|PF00415	-	-	-	-	-
115436	10133	RP11-730A19.1	OPTN	ALS12|FIP2|GLC1E|HIP7|HYPL|NRP|TFIIIA-INTP	9606	Homo sapiens	692	85	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CC2-LZ|NEMO	PF16516|PF11577	-	-	-	-	-
115437	10134	-	BCAP31	6C6-AG|BAP31|CDM|DDCH|DXS1357E	9606	Homo sapiens	794	98	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Bap31|Bap31_Bap29_C	PF05529|PF18035	-	-	-	-	-
107315	867	-	CBL	C-CBL|CBL2|FRA11B|NSLL|RNF55	9606	Homo sapiens	1477	17	0	BIOGRID	NEDD8 E3|Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cbl_N|Cbl_N2|Cbl_N3|UBA	PF02262|PF02761|PF02762|PF00627	-	-	-	-	-
138920	493829	-	TRIM72	MG53	9606	Homo sapiens	102	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
938867	100287205	-	USP17L12	-	9606	Homo sapiens	6	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
110730	4646	RP3-472A9.1	MYO6	DFNA22|DFNB37	9606	Homo sapiens	625	401	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Myosin-VI_CBD|Myosin_head	PF16521|PF00063	-	-	-	-	-
129937	284697	-	BTBD8	-	9606	Homo sapiens	7	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
34074	853806	YKL059C	MPE1	-	559292	Saccharomyces cerevisiae (S288c)	375	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DWNN	PF08783	-	-	-	-	-
34079	853811	YKL054C	DEF1	VID31|DNA damage-responsive RNA polymerase-degradation factor DEF1	559292	Saccharomyces cerevisiae (S288c)	505	16	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
114892	9515	-	STXBP5L	LLGL4	9606	Homo sapiens	256	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LLGL|Lgl_C|WD40	PF08366|PF08596|PF00400	-	-	-	-	-
115548	10254	-	STAM2	Hbp|STAM2A|STAM2B	9606	Homo sapiens	242	19	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SH3_1|UIM|VHS	PF00018|PF02809|PF00790	-	-	-	-	-
107028	546	RP5-875J14.1	ATRX	ATR2|JMS|MRXHF1|RAD54|RAD54L|SFM1|SHS|XH2|XNP|ZNF-HX	9606	Homo sapiens	452	211	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ADD_ATRX|Helicase_C|SNF2_N	PF17981|PF00271|PF00176	-	-	-	-	-
123080	80028	-	FBXL18	Fbl18	9606	Homo sapiens	89	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
123245	80335	UNQ9342/PRO34047	WDR82	MST107|MSTP107|PRO2730|PRO34047|SWD2|TMEM113|WDR82A	9606	Homo sapiens	338	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
129592	283518	RP11-34F20.6	KCNRG	DLTET	9606	Homo sapiens	19	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
111919	5987	DAAP-182E11.3	TRIM27	RFP|RNF76	9606	Homo sapiens	781	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
34455	854222	YOR057W	SGT1	YOR29-08|L000003443|L000004087	559292	Saccharomyces cerevisiae (S288c)	837	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CS|SGS	PF04969|PF05002	-	-	-	-	-
31628	851083	YLR368W	MDM30	DSG1|SCF ubiquitin ligase complex subunit MDM30	559292	Saccharomyces cerevisiae (S288c)	130	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
31153	850555	YFR005C	SAD1	L000001795	559292	Saccharomyces cerevisiae (S288c)	528	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
31152	850554	YFR004W	RPN11	MPR1|proteasome regulatory particle lid subunit RPN11|L000002976|L000002965	559292	Saccharomyces cerevisiae (S288c)	2806	10	0	BIOGRID	Deubiquitinating enzyme (DUB)|Proteasome	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
31440	850864	YLR167W	RPS31	RPS37|UBI3|ubiquitin-ribosomal 40S subunit protein S31 fusion protein|S31e|UB13|YS24|S37|S31|L000001768|L000002413	559292	Saccharomyces cerevisiae (S288c)	401	25	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	Ribosomal_S27|ubiquitin	PF01599|PF00240	-	-	-	-	-
117614	26223	-	FBXL21	FBL3B|FBXL3B|FBXL3P|Fbl21	9606	Homo sapiens	19	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
117615	26224	-	FBXL3	FBL3|FBL3A|FBXL3A	9606	Homo sapiens	68	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
117964	27033	-	ZBTB32	FAXF|FAZF|Rog|TZFP|ZNF538	9606	Homo sapiens	87	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
32456	852003	YDR394W	RPT3	YNT1|YTA2|proteasome regulatory particle base subunit RPT3|L000002556|L000002537	559292	Saccharomyces cerevisiae (S288c)	798	18	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|Prot_ATP_ID_OB	PF00004|PF16450	-	-	-	-	-
108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	481	213	9	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	KA1|Pkinase|UBA	PF02149|PF00069|PF00627	-	-	-	-	-
107339	899	-	CCNF	FBX1|FBXO1	9606	Homo sapiens	3718	18	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cyclin_C|Cyclin_N|F-box	PF02984|PF00134|PF00646	-	-	-	-	-
109231	2976	-	GTF3C2	TFIIIC-BETA|TFIIIC110	9606	Homo sapiens	273	61	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
119101	50626	-	CYHR1	CHRP	9606	Homo sapiens	62	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
127186	149041	RP5-1198E17.5	RC3H1	RNF198|ROQUIN	9606	Homo sapiens	896	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ROQ_II|zf-CCCH|zf-RING_UBOX	PF18386|PF00642|PF13445	-	-	-	-	-
35819	855726	YNL006W	LST8	TOR complex subunit LST8|L000004356	559292	Saccharomyces cerevisiae (S288c)	993	0	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
126213	129868	-	TRIM43	TRIM43A	9606	Homo sapiens	65	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
35817	855724	YNL008C	ASI3	putative ubiquitin-protein ligase ASI3	559292	Saccharomyces cerevisiae (S288c)	155	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
127342	151112	-	ZSWIM2	MEX|ZZZ2	9606	Homo sapiens	20	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SWIM|ZZ|zf-RING_2	PF04434|PF00569|PF13639	-	-	-	-	-
120348	55016	-	MARCH1	MARCH-I|RNF171	9606	Homo sapiens	94	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
120699	55527	-	FEM1A	EPRAP	9606	Homo sapiens	117	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2	PF12796	-	-	-	-	-
120340	55008	RP11-10L7.1	HERC6	-	9606	Homo sapiens	17	30	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|RCC1	PF00632|PF00415	-	-	-	-	-
35494	855362	YMR314W	PRE5	proteasome core particle subunit alpha 6|L000001487	559292	Saccharomyces cerevisiae (S288c)	280	9	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
120695	55521	-	TRIM36	HAPRIN|RBCC728|RNF98	9606	Homo sapiens	153	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	COS|fn3|zf-B_box|zf-RING_UBOX	PF18568|PF00041|PF00643|PF13445	-	-	-	-	-
35658	855549	YNL172W	APC1	anaphase promoting complex subunit 1|L000004053	559292	Saccharomyces cerevisiae (S288c)	612	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC1	PF12859	-	-	-	-	-
34708	854500	YOR322C	LDB19	ART1	559292	Saccharomyces cerevisiae (S288c)	253	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LDB19	PF13002	-	-	-	-	-
115961	10738	RP1-149A16.1	RFPL3	-	9606	Homo sapiens	29	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|RDM|SPRY	PF13765|PF11002|PF00622	-	-	-	-	-
117545	26094	-	DCAF4	WDR21|WDR21A	9606	Homo sapiens	473	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117540	26088	RP1-37E16.3	GGA1	-	9606	Homo sapiens	240	110	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Alpha_adaptinC2|GAT|GGA_N-GAT|VHS	PF02883|PF03127|PF18308|PF00790	-	-	-	-	-
124085	84447	-	SYVN1	DER3|HRD1	9606	Homo sapiens	602	12	1	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	40	18	3	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
119578	51507	AD-007	RTFDC1	C20orf43|CDAO5|HSPC164|SHUJUN-3	9606	Homo sapiens	90	52	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116569	22905	-	EPN2	EHB21	9606	Homo sapiens	130	44	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH	PF01417	-	-	-	-	-
128969	253461	-	ZBTB38	CIBZ|PPP1R171|ZNF921	9606	Homo sapiens	183	69	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
116567	22903	RP4-742J24.3	BTBD3	dJ742J24.1	9606	Homo sapiens	25	82	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|PHR	PF07707|PF00651|PF08005	-	-	-	-	-
128962	253260	-	RICTOR	AVO3|PIA|hAVO3	9606	Homo sapiens	1114	255	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RICTOR_M|RICTOR_N|RICTOR_V|RICTOR_phospho|RasGEF_N_2	PF14666|PF14664|PF14668|PF14665|PF14663	-	-	-	-	-
119809	53840	-	TRIM34	IFP1|RNF21	9606	Homo sapiens	44	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	105	81	3	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
107800	1410	-	CRYAB	CMD1II|CRYA2|CTPP2|CTRCT16|HEL-S-101|HSPB5|MFM2	9606	Homo sapiens	396	53	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Crystallin|HSP20	PF00525|PF00011	-	-	-	-	-
135630	403341	RP11-106H5.1	ZBTB34	ZNF918	9606	Homo sapiens	38	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
115125	9781	-	RNF144A	RNF144|UBCE7IP4	9606	Homo sapiens	128	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
116709	23077	AC001226.5	MYCBP2	PAM	9606	Homo sapiens	368	343	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10|PHR|RCC1|SH3_3|zf-RING_2	PF03256|PF08005|PF00415|PF08239|PF13639	-	-	-	-	-
116701	23066	-	CAND2	TIP120B|Tp120b	9606	Homo sapiens	140	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TIP120	PF08623	-	-	-	-	-
32142	851659	YDR086C	SSS1	translocon subunit SSS1|L000002092	559292	Saccharomyces cerevisiae (S288c)	417	4	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	SecE	PF00584	-	-	-	-	-
117382	25862	RP11-298J23.4	USP49	-	9606	Homo sapiens	101	5	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
117141	23608	-	MKRN1	RNF61	9606	Homo sapiens	272	94	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MKRN1_C|zf-C3HC4|zf-CCCH|zf-CCCH_4	PF15815|PF00097|PF00642|PF18044	-	-	-	-	-
119975	54469	HT032	ZFAND6	AWP1|ZA20D3|ZFAND5B	9606	Homo sapiens	38	84	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-A20|zf-AN1	PF01754|PF01428	-	-	-	-	-
119973	54467	-	ANKIB1	-	9606	Homo sapiens	21	26	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|IBR	PF00023|PF01485	-	-	-	-	-
130174	285671	-	RNF180	RINES	9606	Homo sapiens	33	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
119978	54472	-	TOLLIP	IL-1RAcPIP	9606	Homo sapiens	472	26	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	C2|CUE	PF00168|PF02845	-	-	-	-	-
120525	55230	-	USP40	-	9606	Homo sapiens	56	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
124867	91694	-	LONRF1	RNF191	9606	Homo sapiens	130	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LON_substr_bdg|zf-RING_UBOX	PF02190|PF13445	-	-	-	-	-
124642	89910	-	UBE3B	BPIDS	9606	Homo sapiens	84	28	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
121835	58508	-	KMT2C	HALR|MLL3	9606	Homo sapiens	220	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FYRC|FYRN|PHD|SET	PF05965|PF05964|PF00628|PF00856	-	-	-	-	-
125841	123879	-	DCUN1D3	44M2.4	9606	Homo sapiens	78	1	0	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
120528	55234	RP11-54K16.3	SMU1	BWD|SMU-1|fSAP57	9606	Homo sapiens	284	28	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
120529	55236	-	UBA6	E1-L2|MOP-4|UBE1L2	9606	Homo sapiens	281	81	0	BIOGRID	Ubiquitin activating enzyme (E1)	-	-	-	-	-	-	E1_4HB|E1_FCCH|E1_UFD|ThiF|UBA_e1_thiolCys	PF16191|PF16190|PF09358|PF00899|PF10585	-	-	-	-	-
113180	7332	-	UBE2L3	E2-F1|L-UBC|UBCH7|UbcM4	9606	Homo sapiens	646	65	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
116639	22992	-	KDM2A	CXXC8|FBL11|FBL7|FBXL11|JHDM1A|LILINA	9606	Homo sapiens	131	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|JHD|PHD_4|zf-CXXC	PF00646|PF17811|PF16866|PF02008	-	-	-	-	-
125593	117584	-	RFFL	CARP-2|CARP2|FRING|RIFIFYLIN|RNF189|RNF34L	9606	Homo sapiens	128	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
125596	117854	-	TRIM6	RNF89	9606	Homo sapiens	105	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box|zf-RING_UBOX	PF00622|PF00643|PF13445	-	-	-	-	-
36753	856740	YER019C-A	SBH2	SEB2|Arf family guanine nucleotide exchange factor SBH2|L000002847|L000004138	559292	Saccharomyces cerevisiae (S288c)	143	0	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Sec61_beta	PF03911	-	-	-	-	-
125598	118424	RP5-902P8.8	UBE2J2	NCUBE-2|NCUBE2|PRO2121	9606	Homo sapiens	57	76	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
119594	51533	-	PHF7	HSPC045|HSPC226|NYD-SP6	9606	Homo sapiens	39	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
119591	51529	HSPC214	ANAPC11	APC11|Apc11p	9606	Homo sapiens	257	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-ANAPC11	PF12861	-	-	-	-	-
119592	51530	HSPC216	ZC3HC1	NIPA	9606	Homo sapiens	175	72	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Rsm1|zf-C3HC	PF08600|PF07967	-	-	-	-	-
113041	7189	-	TRAF6	MGC:3310|RNF85	9606	Homo sapiens	1269	15	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TRAF6_Z2|zf-TRAF	PF18048|PF02176	-	-	-	-	-
113040	7188	RP11-318L16.2	TRAF5	MGC:39780|RNF84	9606	Homo sapiens	194	67	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4|zf-TRAF	PF00097|PF02176	-	-	-	-	-
113515	7726	DAAP-200B17.5	TRIM26	AFP|RNF95|ZNF173	9606	Homo sapiens	276	79	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
112393	6502	-	SKP2	FBL1|FBXL1|FLB1|p45	9606	Homo sapiens	849	47	8	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	1426	31	6	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Skp1|Skp1_POZ	PF01466|PF03931	-	-	-	-	-
113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	1328	7	501	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	VHL|VHL_C	PF01847|PF17211	-	-	-	-	-
121014	55968	RP4-776F14.2	NSFL1C	P47|UBX1|UBXD10|UBXN2C|dJ776F14.1	9606	Homo sapiens	267	218	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SEP|UBX	PF08059|PF00789	-	-	-	-	-
36134	856061	YPL046C	ELC1	elongin C|L000004351	559292	Saccharomyces cerevisiae (S288c)	195	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Skp1_POZ	PF03931	-	-	-	-	-
120833	55709	-	KBTBD4	BKLHD4|HSPC252	9606	Homo sapiens	353	77	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB	PF07707|PF00651	-	-	-	-	-
33381	853034	YGR133W	PEX4	PAS2|UBC10|E2 ubiquitin-protein ligase peroxin 4|L000001338	559292	Saccharomyces cerevisiae (S288c)	277	0	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
33383	853036	YGR135W	PRE9	proteasome core particle subunit alpha 3|L000002701	559292	Saccharomyces cerevisiae (S288c)	1015	17	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
113601	7844	-	RNF103	HKF-1|KF-1|KF1|ZFP-103|ZFP103	9606	Homo sapiens	31	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
33141	852768	YGL110C	CUE3	-	559292	Saccharomyces cerevisiae (S288c)	154	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
32310	851847	YDR260C	SWM1	APC13|L000004027	559292	Saccharomyces cerevisiae (S288c)	333	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Apc13p	PF05839	-	-	-	-	-
133459	390231	-	TRIM77	TRIM77P	9606	Homo sapiens	1	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-C3HC4	PF00622|PF00097	-	-	-	-	-
122475	79004	HOYS6	CUEDC2	C10orf66|bA18I14.5	9606	Homo sapiens	76	16	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
113867	8239	RP5-1172N10.4	USP9X	DFFRX|FAF|FAM|MRX99	9606	Homo sapiens	710	182	3	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUF3517|UCH	PF12030|PF00443	-	-	-	-	-
113866	8237	RP4-659F15.2	USP11	UHX1	9606	Homo sapiens	768	82	2	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|UCH|USP7_C2|Ubiquitin_3	PF06337|PF00443|PF14533|PF14836	-	-	-	-	-
115602	10318	-	TNIP1	ABIN-1|NAF1|VAN|nip40-1	9606	Homo sapiens	1430	230	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
115607	10324	-	KLHL41	KBTBD10|Krp1|NEM9|SARCOSIN	9606	Homo sapiens	37	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121651	57602	-	USP36	DUB1	9606	Homo sapiens	719	88	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
34844	854658	YIL148W	RPL40A	CEP52A|UB11|UBI1|ubiquitin-ribosomal 60S subunit protein L40A fusion protein|L40e|L40A|L000002411|L000000313	559292	Saccharomyces cerevisiae (S288c)	241	15	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	Ribosomal_L40e|ubiquitin	PF01020|PF00240	-	-	-	-	-
121657	57610	-	RANBP10	-	9606	Homo sapiens	260	46	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH|LisH|SPRY	PF10607|PF08513|PF00622	-	-	-	-	-
32761	852349	YBR058C	UBP14	GID6|L000003173	559292	Saccharomyces cerevisiae (S288c)	334	22	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|UCH|zf-UBP|zf-UBP_var	PF00627|PF00443|PF02148|PF17807	-	-	-	-	-
123879	84085	RP11-545I5.4	FBXO30	Fbx30	9606	Homo sapiens	88	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box_4|zf-TRAF_2	PF15966|PF15965	-	-	-	-	-
127739	159195	RP11-137L10.4	USP54	C10orf29|bA137L10.3|bA137L10.4	9606	Homo sapiens	270	194	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
123873	84078	-	KBTBD7	-	9606	Homo sapiens	404	18	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
36627	856600	YHR193C	EGD2	L000000546|L000002606	559292	Saccharomyces cerevisiae (S288c)	392	11	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	HYPK_UBA|NAC	PF19026|PF01849	-	-	-	-	-
33708	853400	YJL047C	RTT101	CUL8|cullin RTT101|CULC|L000004737	559292	Saccharomyces cerevisiae (S288c)	463	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
939174	100287513	-	USP17L22	-	9606	Homo sapiens	8	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
34283	854032	YOL117W	RRI2	CSN10|S000007579	559292	Saccharomyces cerevisiae (S288c)	90	1	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	-	-	-	-	-	-	-
123657	83461	-	CDCA3	GRCC8|TOME-1	9606	Homo sapiens	251	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
109939	3736	-	KCNA1	AEMK|EA1|HBK1|HUK1|KV1.1|MBK1|MK1|RBK1	9606	Homo sapiens	26	1	17	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	161	11	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|Ank_2	PF00023|PF12796	-	-	-	-	-
569148	643904	-	RNF222	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_UBOX	PF13445	-	-	-	-	-
123896	84108	-	PCGF6	MBLR|RNF134	9606	Homo sapiens	340	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
123890	84101	-	USP44	-	9606	Homo sapiens	228	7	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
109957	3755	RP5-955M13.1	KCNG1	K13|KCNG|KV6.1|kH2	9606	Homo sapiens	30	37	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
938806	100287144	-	USP17L10	-	9606	Homo sapiens	3	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
115738	10475	-	TRIM38	RNF15|RORET	9606	Homo sapiens	72	37	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
33567	853242	YJL197W	UBP12	L000003033	559292	Saccharomyces cerevisiae (S288c)	173	12	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
115735	10472	-	ZBTB18	C2H2-171|MRD22|RP58|TAZ-1|ZNF238	9606	Homo sapiens	82	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
115047	9695	-	EDEM1	EDEM	9606	Homo sapiens	271	4	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Glyco_hydro_47	PF01532	-	-	-	-	-
131985	375593	-	TRIM73	TRIM50B	9606	Homo sapiens	21	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
107031	550	-	AUP1	-	9606	Homo sapiens	396	19	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
124999	93082	hCG_1641111	NEURL3	LINCR	9606	Homo sapiens	33	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Neuralized	PF07177	-	-	-	-	-
123098	80067	-	DCAF17	C2orf37	9606	Homo sapiens	28	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DCAF17	PF15802	-	-	-	-	-
109337	3090	-	HIC1	ZBTB29|ZNF901|hic-1	9606	Homo sapiens	77	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
110277	4103	-	MAGEA4	CT1.4|MAGE-41|MAGE-X2|MAGE4|MAGE4A|MAGE4B	9606	Homo sapiens	120	50	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
122303	64795	-	RMND5A	CTLH|GID2|GID2A|RMD5|p44CTLH	9606	Homo sapiens	325	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
123258	80352	DADB-60O11.8	RNF39	HZF|HZFW|LIRF	9606	Homo sapiens	15	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|zf-C3HC4	PF13765|PF00097	-	-	-	-	-
123255	80349	-	WDR61	REC14|SKI8	9606	Homo sapiens	315	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
123251	80344	GL014	DCAF11	PRO2389|WDR23	9606	Homo sapiens	293	23	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
34443	854206	YOR042W	CUE5	-	559292	Saccharomyces cerevisiae (S288c)	141	54	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
31638	851095	YLR378C	SEC61	translocon subunit SEC61|L000001852	559292	Saccharomyces cerevisiae (S288c)	3033	3	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Plug_translocon|SecY	PF10559|PF00344	-	-	-	-	-
111105	5071	KB-152G3.1	PARK2	AR-JP|LPRS2|PDJ|PRKN	9606	Homo sapiens	5964	50	1	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR|ubiquitin|zf-RING_12|zf-RING_14	PF01485|PF00240|PF17976|PF17978	-	-	-	-	-
114552	9098	-	USP6	HRP1|TRE17|TRE2|TRESMCR|Tre-2|USP6-short	9606	Homo sapiens	40	33	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	RabGAP-TBC|UCH	PF00566|PF00443	-	-	-	-	-
114553	9099	-	USP2	UBP41|USP9	9606	Homo sapiens	378	22	8	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
114551	9097	-	USP14	TGT	9606	Homo sapiens	751	65	17	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
114554	9100	-	USP10	UBPO	9606	Homo sapiens	631	157	2	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	PAM2|UCH	PF07145|PF00443	-	-	-	-	-
114555	9101	-	USP8	HumORF8|SPG59|UBPY	9606	Homo sapiens	315	83	4	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Rhodanese|UCH|USP8_dimer	PF00581|PF00443|PF08969	-	-	-	-	-
117603	26190	RP11-88M19.2	FBXW2	FBW2|Fwd2|Md6	9606	Homo sapiens	93	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
35710	855607	YNL116W	DMA2	CHF2|ubiquitin-conjugating protein DMA2|S000029720	559292	Saccharomyces cerevisiae (S288c)	235	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FHA|zf-RING_11	PF00498|PF17123	-	-	-	-	-
131183	342538	-	NACA2	ANAC|NACAL	9606	Homo sapiens	27	4	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	HYPK_UBA|NAC	PF19026|PF01849	-	-	-	-	-
114397	8878	-	SQSTM1	A170|OSIL|PDB3|ZIP3|p60|p62|p62B	9606	Homo sapiens	2494	66	1	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	PB1|UBA_5|ZZ	PF00564|PF16577|PF00569	-	-	-	-	-
34661	854446	YOR272W	YTM1	CST14|L000003547|L000002998|S000029121	559292	Saccharomyces cerevisiae (S288c)	538	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	NLE|WD40	PF08154|PF00400	-	-	-	-	-
126682	140739	-	UBE2F	NCE2	9606	Homo sapiens	54	27	0	BIOGRID	NEDD8 E2	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
107324	881	RP11-421H8.4	CCIN	BTBD20|KBTBD14	9606	Homo sapiens	12	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
110748	4666	HSD48	NACA	NACA1|skNAC	9606	Homo sapiens	326	160	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	HYPK_UBA|NAC	PF19026|PF01849	-	-	-	-	-
127156	148581	RP4-636O23.1	UBE2U	-	9606	Homo sapiens	148	0	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
122436	65987	-	KCTD14	-	9606	Homo sapiens	26	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
126979	146330	-	FBXL16	C16orf22|Fbl16|c380A1.1	9606	Homo sapiens	48	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_6	PF13516	-	-	-	-	-
31902	851392	YDL161W	ENT1	-	559292	Saccharomyces cerevisiae (S288c)	251	30	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH	PF01417	-	-	-	-	-
114179	8624	-	PSMG1	C21LRP|DSCR2|LRPC21|PAC-1|PAC1	9606	Homo sapiens	176	55	0	BIOGRID	Proteasome	-	-	-	-	-	-	PAC1	PF16094	-	-	-	-	-
126977	146310	-	RNF151	-	9606	Homo sapiens	137	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
107920	1540	HSPC057	CYLD	BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2	9606	Homo sapiens	1145	129	2	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	CAP_GLY|UCH	PF01302|PF00443	-	-	-	-	-
120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	583	16	7	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C65	PF10275	-	-	-	-	-
116828	23221	-	RHOBTB2	DBC2	9606	Homo sapiens	198	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Ras	PF00651|PF00071	-	-	-	-	-
116826	23219	-	FBXO28	CENP-30|Fbx28	9606	Homo sapiens	215	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
116827	23220	-	DTX4	RNF155	9606	Homo sapiens	30	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DTC|WWE|zf-C3HC4	PF18102|PF02825|PF00097	-	-	-	-	-
124986	92912	-	UBE2Q2	-	9606	Homo sapiens	37	8	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
116551	22884	RP11-529L18.2	WDR37	-	9606	Homo sapiens	114	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
110253	4077	MIG19	NBR1	1A1-3B|IAI3B|M17S2	9606	Homo sapiens	491	168	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	N_BRCA1_IG|PB1|ZZ	PF16158|PF00564|PF00569	-	-	-	-	-
116554	22888	RP5-1187M17.9	UBOX5	RNF37|UBCE7IP5|UIP5|hUIP5	9606	Homo sapiens	34	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	U-box	PF04564	-	-	-	-	-
131369	345930	RP3-509I19.3	ECT2L	ARHGEF32|C6orf91|FBXO49|LFDH|dJ509I19.2|dJ509I19.3|dJ509I19.5	9606	Homo sapiens	66	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF4347|F-box-like|RhoGEF	PF14252|PF12937|PF00621	-	-	-	-	-
116556	22890	-	ZBTB1	ZNF909	9606	Homo sapiens	159	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
119748	53347	-	UBASH3A	CLIP4|STS-2|TULA|TULA-1	9606	Homo sapiens	157	86	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	His_Phos_1|SH3_9	PF00300|PF14604	-	-	-	-	-
119740	53339	-	BTBD1	C15orf1|NS5ATP8	9606	Homo sapiens	215	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|PHR	PF07707|PF00651|PF08005	-	-	-	-	-
114774	9373	-	PLAA	DOA1|PLA2P|PLAP	9606	Homo sapiens	148	90	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	PFU|PUL|WD40	PF09070|PF08324|PF00400	-	-	-	-	-
31855	851337	YDL190C	UFD2	ubiquitin-ubiquitin ligase UFD2|L000002788	559292	Saccharomyces cerevisiae (S288c)	376	38	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	U-box|Ufd2P_core	PF04564|PF10408	-	-	-	-	-
32620	852194	YBL084C	CDC27	APC3|SNB1|anaphase promoting complex subunit CDC27|L000000266	559292	Saccharomyces cerevisiae (S288c)	638	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TPR_1|TPR_8	PF00515|PF13181	-	-	-	-	-
120353	55023	RP11-173D14.2	PHIP	BRWD2|DCAF14|WDR11|ndrp	9606	Homo sapiens	264	123	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|WD40	PF00439|PF00400	-	-	-	-	-
127799	161725	-	OTUD7A	C15orf16|C16ORF15|CEZANNE2|OTUD7	9606	Homo sapiens	28	4	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	OTU|zf-A20	PF02338|PF01754	-	-	-	-	-
120359	55030	CGI-301	FBXO34	Fbx34	9606	Homo sapiens	71	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116736	23113	RP3-330M21.2	CUL9	H7AP1|PARC	9606	Homo sapiens	250	113	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10|Cul7|Cullin|IBR	PF03256|PF11515|PF00888|PF01485	-	-	-	-	-
124219	84708	UNQ574/PRO1136	LNX1	LNX|MPDZ|PDZRN2	9606	Homo sapiens	710	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PDZ	PF00595	-	-	-	-	-
120228	54880	-	BCOR	ANOP2|MAA2|MCOPS2	9606	Homo sapiens	467	223	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|BCOR|PUFD	PF12796|PF15808|PF16553	-	-	-	-	-
120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	106	47	6	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DCA16	PF15349	-	-	-	-	-
124189	84669	-	USP32	NY-REN-60|USP10	9606	Homo sapiens	165	72	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|EF-hand_5|UCH	PF06337|PF13202|PF00443	-	-	-	-	-
117397	25886	-	POC1A	PIX2|SOFT|WDR51A	9606	Homo sapiens	187	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
128736	221504	DASS-97D12.7	ZBTB9	ZNF919	9606	Homo sapiens	159	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
117393	25879	HSPC064	DCAF13	GM83|WDSOF1	9606	Homo sapiens	280	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sof1|WD40|eIF2A	PF04158|PF00400|PF08662	-	-	-	-	-
117156	23624	-	CBLC	CBL-3|CBL-SL|RNF57	9606	Homo sapiens	120	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cbl_N|Cbl_N2|Cbl_N3	PF02262|PF02761|PF02762	-	-	-	-	-
129125	255877	-	BCL6B	BAZF|ZBTB28|ZNF62	9606	Homo sapiens	38	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
106868	373	-	TRIM23	ARD1|ARFD1|RNF46	9606	Homo sapiens	467	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arf|zf-B_box|zf-RING_5	PF00025|PF00643|PF14634	-	-	-	-	-
124322	84878	-	ZBTB45	ZNF499	9606	Homo sapiens	8	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
124320	84875	-	PARP10	ARTD10	9606	Homo sapiens	61	8	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	PARP	PF00644	-	-	-	-	-
128358	200933	-	FBXO45	Fbx45	9606	Homo sapiens	277	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|SPRY	PF12937|PF00622	-	-	-	-	-
129019	254170	-	FBXO33	BMND12|Fbx33|c14_5247	9606	Homo sapiens	37	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
128350	200845	-	KCTD6	KCASH3	9606	Homo sapiens	101	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
129210	257240	RP11-450P7.3	KLHL34	-	9606	Homo sapiens	79	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
116608	22954	RP11-67K19.1	TRIM32	BBS11|HT2A|LGMD2H|TATIP	9606	Homo sapiens	372	114	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	NHL|zf-RING_UBOX	PF01436|PF13445	-	-	-	-	-
121244	56916	-	SMARCAD1	ADERM|ETL1|HEL1	9606	Homo sapiens	274	191	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Helicase_C|SNF2_N	PF00271|PF00176	-	-	-	-	-
111671	5698	DADB-223G19.3	PSMB9	LMP2|PSMB6i|RING12|beta1i	9606	Homo sapiens	275	3	5	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
125615	118611	RP11-422P15.2	C10orf90	FATS|bA422P15.2	9606	Homo sapiens	17	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ALMS_motif|Centro_C10orf90	PF15309|PF17730	-	-	-	-	-
129216	257397	-	TAB3	MAP3K7IP3|NAP1	9606	Homo sapiens	134	4	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
122914	79819	RP11-342H21.1	WDR78	DIC4	9606	Homo sapiens	3	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	2558	142	34	BIOGRID	ER-associated degradation (ERAD)|Endosome and golgi-associated degradation (EGAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	AAA|AAA_lid_3|CDC48_2|CDC48_N|Vps4_C	PF00004|PF17862|PF02933|PF02359|PF09336	-	-	-	-	-
113703	7994	-	KAT6A	MOZ|MYST3|RUNXBP2|ZC2HC6A|ZNF220	9606	Homo sapiens	577	33	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MOZ_SAS|PHD|zf-MYST	PF01853|PF00628|PF17772	-	-	-	-	-
125038	93611	RP3-330O12.2	FBXO44	FBG3|FBX30|FBX6A|Fbx44|Fbxo6a	9606	Homo sapiens	79	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|FBA	PF12937|PF04300	-	-	-	-	-
125033	93550	RP11-358L16.1	ZFAND4	ANUBL1	9606	Homo sapiens	23	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ubiquitin|zf-AN1	PF00240|PF01428	-	-	-	-	-
33609	853292	YJL149W	DAS1	SCF ubiquitin ligase complex subunit DAS1	559292	Saccharomyces cerevisiae (S288c)	106	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
133110	389362	RP11-506K6.3	PSMG4	C6orf86|PAC4|bA506K6.2	9606	Homo sapiens	95	4	0	BIOGRID	Proteasome	-	-	-	-	-	-	PAC4	PF16093	-	-	-	-	-
33603	853283	YJL157C	FAR1	cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1|L000000600	559292	Saccharomyces cerevisiae (S288c)	183	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121664	57617	-	VPS18	PEP3	9606	Homo sapiens	268	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Clathrin|Pep3_Vps18	PF00637|PF05131	-	-	-	-	-
121667	57621	-	ZBTB2	ZNF437	9606	Homo sapiens	512	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
122461	78990	-	OTUB2	C14orf137|OTB2|OTU2	9606	Homo sapiens	142	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C65	PF10275	-	-	-	-	-
122863	79752	-	ZFAND1	-	9606	Homo sapiens	21	3	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	zf-AN1	PF01428	-	-	-	-	-
113498	7704	-	ZBTB16	PLZF|ZNF145	9606	Homo sapiens	322	2	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
113497	7703	-	PCGF2	MEL-18|RNF110|ZNF144	9606	Homo sapiens	242	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	1540	1909	2	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF908|DUF913|HECT|UBA|UBM|WWE	PF06012|PF06025|PF00632|PF00627|PF14377|PF02825	-	-	-	-	-
575596	653192	-	TRIM43B	-	9606	Homo sapiens	3	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
33917	853629	YKL206C	ADD66	PBA2|POC2	559292	Saccharomyces cerevisiae (S288c)	238	1	0	BIOGRID	Proteasome	-	-	-	-	-	-	PAC2	PF09754	-	-	-	-	-
107140	672	-	BRCA1	BRCAI|BRCC1|BROVCA1|FANCS|IRIS|PNCA4|PPP1R53|PSCP|RNF53	9606	Homo sapiens	2597	107	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BRCT|BRCT_assoc|zf-C3HC4	PF00533|PF12820|PF00097	-	-	-	-	-
122265	64750	-	SMURF2	-	9606	Homo sapiens	486	5	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
115709	10444	-	ZER1	C9orf60|ZYG|ZYG11BL	9606	Homo sapiens	143	57	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
608698	728269	-	MAGEA9B	-	9606	Homo sapiens	15	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE_N	PF12440	-	-	-	-	-
115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	1721	16	9	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CHIP_TPR_N|U-box	PF18391|PF04564	-	-	-	-	-
115566	10277	-	UBE4B	E4|HDNB1|UBOX3|UFD2|UFD2A	9606	Homo sapiens	201	193	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	U-box|Ufd2P_core	PF04564|PF10408	-	-	-	-	-
31280	850693	YLR007W	NSE1	-	559292	Saccharomyces cerevisiae (S288c)	344	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SMC_Nse1|zf-RING-like	PF07574|PF08746	-	-	-	-	-
126566	139422	-	MAGEB10	-	9606	Homo sapiens	105	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
34012	853735	YKL124W	SSH4	MLF4|L000002951	559292	Saccharomyces cerevisiae (S288c)	89	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
122315	64839	-	FBXL17	FBXO13|Fbl17|Fbx13	9606	Homo sapiens	157	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|LRR_6	PF12937|PF13516	-	-	-	-	-
122319	64844	-	MARCH7	AXO|AXOT|MARCH-VII|RNF177	9606	Homo sapiens	137	101	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
123224	80311	-	KLHL15	HEL-S-305	9606	Homo sapiens	172	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
32857	852455	YBR158W	AMN1	CST13|ICS4|L000002997	559292	Saccharomyces cerevisiae (S288c)	100	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
34479	854247	YOR080W	DIA2	YOR29-31|DNA-binding SCF ubiquitin ligase subunit DIA2	559292	Saccharomyces cerevisiae (S288c)	1160	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|LRR_1	PF00646|PF00560	-	-	-	-	-
115413	10107	DAAP-200B17.4	TRIM10	HERF1|RFB30|RNF9	9606	Homo sapiens	97	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
114946	9577	-	BRE	BRCC4|BRCC45	9606	Homo sapiens	213	53	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	BRE	PF06113	-	-	-	-	-
129334	266740	-	MAGEA2B	MAGE2|MAGEA2	9606	Homo sapiens	35	22	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
129804	284252	hCG_38480	KCTD1	C18orf5|SENS	9606	Homo sapiens	67	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
34651	854435	YOR261C	RPN8	proteasome regulatory particle lid subunit RPN8|L000004308	559292	Saccharomyces cerevisiae (S288c)	770	27	0	BIOGRID	Proteasome	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
34122	853859	YKL010C	UFD4	putative ubiquitin-protein ligase UFD4|L000003509	559292	Saccharomyces cerevisiae (S288c)	223	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
117941	26994	CGI-123	RNF11	SID1669	9606	Homo sapiens	270	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
31468	850896	YLR199C	PBA1	POC1	559292	Saccharomyces cerevisiae (S288c)	166	4	0	BIOGRID	Proteasome	-	-	-	-	-	-	POC1	PF10450	-	-	-	-	-
568729	643376	hCG_1730474	BTBD18	-	9606	Homo sapiens	4	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
119121	50717	RP11-574F21.1	DCAF8	GAN2|H326|WDR42A	9606	Homo sapiens	270	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
31194	850597	YFR036W	CDC26	HIT3|SCD26|anaphase promoting complex subunit CDC26|L000000265|L000001809	559292	Saccharomyces cerevisiae (S288c)	214	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC_CDC26	PF10471	-	-	-	-	-
35831	855739	YNR006W	VPS27	DID7|GRD11|SSV17|VPL23|VPT27|ESCRT-0 subunit protein VPS27|L000002790	559292	Saccharomyces cerevisiae (S288c)	1204	24	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	FYVE|UIM|VHS	PF01363|PF02809|PF00790	-	-	-	-	-
108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	2963	31	9	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|Creb_binding|DUF902|HAT_KAT11|KIX|ZZ|zf-TAZ	PF00439|PF09030|PF06001|PF08214|PF02172|PF00569|PF02135	-	-	-	-	-
107316	868	Nbla00127	CBLB	Cbl-b|RNF56	9606	Homo sapiens	199	270	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cbl_N|Cbl_N2|Cbl_N3	PF02262|PF02761|PF02762	-	-	-	-	-
31515	850949	YLR247C	IRC20	E3 ubiquitin-protein ligase IRC20	559292	Saccharomyces cerevisiae (S288c)	148	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SNF2_N	PF00176	-	-	-	-	-
31042	850430	YCR066W	RAD18	E3 ubiquitin-protein ligase RAD18|L000001567	559292	Saccharomyces cerevisiae (S288c)	612	13	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SAP	PF02037	-	-	-	-	-
35016	854843	YIR025W	MND2	-	559292	Saccharomyces cerevisiae (S288c)	143	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Apc15p	PF05841	-	-	-	-	-
126769	142678	RP11-345P4.1	MIB2	ZZANK1|ZZZ5	9606	Homo sapiens	101	182	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|MIB_HERC2|SH3_15|ZZ	PF12796|PF06701|PF18346|PF00569	-	-	-	-	-
31047	850435	YCR072C	RSA4	-	559292	Saccharomyces cerevisiae (S288c)	238	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	NLE|WD40	PF08154|PF00400	-	-	-	-	-
109698	3476	RP13-46G5.1	IGBP1	ALPHA-4|IBP1	9606	Homo sapiens	267	39	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	TAP42	PF04177	-	-	-	-	-
32892	852494	YBR195C	MSI1	CAC3|L000001193	559292	Saccharomyces cerevisiae (S288c)	260	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40|eIF2A	PF12265|PF00400|PF08662	-	-	-	-	-
32898	852500	YBR201W	DER1	L000002800	559292	Saccharomyces cerevisiae (S288c)	411	0	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	DER1	PF04511	-	-	-	-	-
111425	5429	RP11-22I24.1	POLH	RAD30|RAD30A|XP-V|XPV	9606	Homo sapiens	185	60	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	IMS|IMS_C|zf_UBZ	PF00817|PF11799|PF18439	-	-	-	-	-
34722	854517	YOR339C	UBC11	putative E2 ubiquitin-protein ligase UBC11|L000004673	559292	Saccharomyces cerevisiae (S288c)	53	0	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
122605	79228	PSEC0006	THOC6	BBIS|WDR58|fSAP35	9606	Homo sapiens	124	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
115962	10739	-	RFPL2	RNF79	9606	Homo sapiens	40	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|RDM|SPRY	PF13765|PF11002|PF00622	-	-	-	-	-
127962	168433	-	RNF133	-	9606	Homo sapiens	28	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
127564	154881	-	KCTD7	CLN14|EPM3	9606	Homo sapiens	108	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
130974	339976	-	TRIML1	RNF209	9606	Homo sapiens	8	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY	PF13765|PF00622	-	-	-	-	-
299847	554251	-	FBXO48	-	9606	Homo sapiens	6	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
120039	54554	-	WDR5B	-	9606	Homo sapiens	79	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
120036	54551	-	MAGEL2	NDNL1|PWLS|nM15	9606	Homo sapiens	66	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
120033	54546	RP11-91K11.1	RNF186	-	9606	Homo sapiens	22	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
32766	852354	YBR062C	YBR062C	-	559292	Saccharomyces cerevisiae (S288c)	45	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124993	92999	-	ZBTB47	ZNF651	9606	Homo sapiens	374	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
124992	92979	-	MARCH9	MARCH-IX|RNF179	9606	Homo sapiens	11	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
35522	855399	YNL317W	PFS2	-	559292	Saccharomyces cerevisiae (S288c)	146	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
117016	23450	-	SF3B3	RSE1|SAP130|SF3b130|STAF130	9606	Homo sapiens	794	35	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CPSF_A	PF03178	-	-	-	-	-
35528	855405	YNL311C	SKP2	putative SCF ubiquitin ligase complex subunit SKP2	559292	Saccharomyces cerevisiae (S288c)	114	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
120327	54994	-	GID8	C20orf11|TWA1	9606	Homo sapiens	248	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH|LisH	PF10607|PF08513	-	-	-	-	-
32385	851928	YDR328C	SKP1	MGO1|SCF ubiquitin ligase subunit SKP1|CBF3D|L000001910	559292	Saccharomyces cerevisiae (S288c)	458	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Skp1|Skp1_POZ	PF01466|PF03931	-	-	-	-	-
116727	23099	RP11-489N22.2	ZBTB43	ZBTB22B|ZNF-X|ZNF297B	9606	Homo sapiens	70	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
32160	851680	YDR103W	STE5	HMD3|NUL3|L000002115	559292	Saccharomyces cerevisiae (S288c)	194	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ste5|Ste5_C	PF11610|PF12194	-	-	-	-	-
120250	54904	DC28	WHSC1L1	NSD3|pp14328	9606	Homo sapiens	162	43	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	AWS|C5HCH|PWWP|SET	PF17907|PF17982|PF00855|PF00856	-	-	-	-	-
32366	851908	YDR313C	PIB1	phosphatidylinositol-3-phosphate-binding ubiquitin-protein ligase|L000004635	559292	Saccharomyces cerevisiae (S288c)	110	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FYVE|zf-RING_2	PF01363|PF13639	-	-	-	-	-
124195	84676	-	TRIM63	IRF|MURF1|MURF2|RNF28|SMRZ	9606	Homo sapiens	415	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
124194	84675	-	TRIM55	MURF-2|RNF29|muRF2	9606	Homo sapiens	503	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
124197	84678	-	KDM2B	CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2	9606	Homo sapiens	250	26	6	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cupin_8|F-box|JHD|PHD_4|zf-CXXC	PF13621|PF00646|PF17811|PF16866|PF02008	-	-	-	-	-
114610	9169	-	SCAF11	CASP11|SFRS2IP|SIP1|SRRP129|SRSF2IP	9606	Homo sapiens	158	195	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
125824	123355	UNQ436/PRO867	LRRC28	-	9606	Homo sapiens	50	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_8	PF13855	-	-	-	-	-
117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	148	4	5	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
130398	286514	-	MAGEB18	-	9606	Homo sapiens	20	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
124668	90135	-	BTBD6	BDPL	9606	Homo sapiens	26	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|PHR	PF07707|PF00651|PF08005	-	-	-	-	-
135277	401934	-	RNF223	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124333	84893	RP11-536K7.6	FBXO18	FBH1|Fbx18	9606	Homo sapiens	70	60	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|UvrD_C	PF12937|PF13361	-	-	-	-	-
124684	90268	-	OTULIN	FAM105B|GUM	9606	Homo sapiens	274	35	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C101	PF16218	-	-	-	-	-
121256	56929	-	FEM1C	EUROIMAGE686608|EUROIMAGE783647|FEM1A	9606	Homo sapiens	37	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2	PF12796	-	-	-	-	-
124688	90293	-	KLHL13	BKLHD2	9606	Homo sapiens	189	184	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
113067	7216	RP6-14C6.1	TRO	MAGE-d3|MAGED3	9606	Homo sapiens	96	227	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
571674	646862	-	RNF225	-	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
113241	7398	-	USP1	UBP	9606	Homo sapiens	287	65	7	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
124536	85451	-	UNK	ZC3H5|ZC3HDC5	9606	Homo sapiens	420	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CCCH|zf_CCCH_5	PF00642|PF18384	-	-	-	-	-
122670	79444	RP11-261N11.7	BIRC7	KIAP|LIVIN|ML-IAP|MLIAP|RNF50	9606	Homo sapiens	111	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR	PF00653	-	-	-	-	-
33163	852793	YGL087C	MMS2	E2  ubiquitin-conjugating protein MMS2|L000004015	559292	Saccharomyces cerevisiae (S288c)	416	3	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
33168	852798	YGL082W	YGL082W	-	559292	Saccharomyces cerevisiae (S288c)	34	7	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	MINDY_DUB	PF04424	-	-	-	-	-
118882	29116	RP1-13D10.1	MYLIP	IDOL|MIR	9606	Homo sapiens	85	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FERM_C|FERM_M|FERM_N	PF09380|PF00373|PF09379	-	-	-	-	-
125956	126119	SBBI54	JOSD2	-	9606	Homo sapiens	77	12	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Josephin	PF02099	-	-	-	-	-
36423	856387	YHL002W	HSE1	ESCRT-0 subunit protein HSE1	559292	Saccharomyces cerevisiae (S288c)	453	9	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SH3_1|VHS	PF00018|PF00790	-	-	-	-	-
568894	643596	-	RNF224	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_UBOX	PF13445	-	-	-	-	-
121673	57630	-	SH3RF1	POSH|RNF142|SH3MD2	9606	Homo sapiens	140	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH3_1|SH3_9	PF00018|PF14604	-	-	-	-	-
121671	57626	RP11-394C23.1	KLHL1	MRP2	9606	Homo sapiens	25	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
122419	65264	HOYS7	UBE2Z	USE1	9606	Homo sapiens	110	9	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
129106	255488	-	RNF144B	IBRDC2|PIR2|bA528A10.3|p53RFP	9606	Homo sapiens	51	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
113800	8139	-	GAN	GAN1|KLHL16	9606	Homo sapiens	328	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
115628	10346	-	TRIM22	GPSTAF50|RNF94|STAF50	9606	Homo sapiens	99	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
33295	852939	YGR048W	UFD1	polyubiquitin-binding protein UFD1|L000002787	559292	Saccharomyces cerevisiae (S288c)	323	13	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UFD1	PF03152	-	-	-	-	-
122781	79654	RP11-69J16.1	HECTD3	-	9606	Homo sapiens	229	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10|HECT	PF03256|PF00632	-	-	-	-	-
113485	7690	-	ZNF131	ZBTB35|pHZ-10	9606	Homo sapiens	163	158	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
122895	79798	-	ARMC5	AIMAH2	9606	Homo sapiens	229	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
122890	79791	PP2386	FBXO31	FBX14|FBXO14|Fbx31|MRT45	9606	Homo sapiens	86	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	1411	41	6	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|Creb_binding|DUF902|HAT_KAT11|KIX|ZZ|zf-TAZ	PF00439|PF09030|PF06001|PF08214|PF02172|PF00569|PF02135	-	-	-	-	-
31295	850708	YLR021W	IRC25	DMP2|PBA3|POC3	559292	Saccharomyces cerevisiae (S288c)	371	1	0	BIOGRID	Proteasome	-	-	-	-	-	-	POC3_POC4	PF10448	-	-	-	-	-
31298	850711	YLR024C	UBR2	putative ubiquitin-protein ligase UBR2	559292	Saccharomyces cerevisiae (S288c)	633	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRT6_C|zf-UBR	PF18995|PF02207	-	-	-	-	-
126574	139562	-	OTUD6A	DUBA2|HSHIN6	9606	Homo sapiens	59	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
126577	139599	-	MAGEE2	HCA3	9606	Homo sapiens	46	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
115085	9736	-	USP34	-	9606	Homo sapiens	233	37	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUF3517|UCH	PF12030|PF00443	-	-	-	-	-
34391	854149	YOL013C	HRD1	DER3|E3 ubiquitin-protein ligase HRD1|L000002963	559292	Saccharomyces cerevisiae (S288c)	409	4	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
31614	851066	YLR352W	YLR352W	-	559292	Saccharomyces cerevisiae (S288c)	126	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117542	26091	RP11-57G10.4	HERC4	-	9606	Homo sapiens	107	393	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|RCC1	PF00632|PF00415	-	-	-	-	-
122327	64854	-	USP46	-	9606	Homo sapiens	151	8	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
123237	80325	PP2259	ABTB1	BPOZ|BTB3|BTBD21|EF1ABP	9606	Homo sapiens	35	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|BTB	PF12796|PF00651	-	-	-	-	-
115402	10095	-	ARPC1B	ARC41|p40-ARC|p41-ARC	9606	Homo sapiens	389	45	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	909	43	21	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
115159	9820	-	CUL7	3M1|KIAA0076|dJ20C7.5	9606	Homo sapiens	1023	173	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10|Cul7|Cullin	PF03256|PF11515|PF00888	-	-	-	-	-
129497	283212	-	KLHL35	-	9606	Homo sapiens	12	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
115409	10102	-	TSFM	EFTS|EFTSMT	9606	Homo sapiens	452	20	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EF_TS	PF00889	-	-	-	-	-
114977	9616	-	RNF7	CKBBP1|ROC2|SAG	9606	Homo sapiens	302	4	1	BIOGRID	NEDD8 E3|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-rbx1	PF12678	-	-	-	-	-
34646	854430	YOR256C	TRE2	-	559292	Saccharomyces cerevisiae (S288c)	25	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Peptidase_M28|TFR_dimer	PF04389|PF04253	-	-	-	-	-
31474	850903	YLR206W	ENT2	-	559292	Saccharomyces cerevisiae (S288c)	255	25	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	ENTH	PF01417	-	-	-	-	-
34649	854433	YOR259C	RPT4	CRL13|PCS1|SUG2|proteasome regulatory particle base subunit RPT4|L000003423|L000003107|L000000413	559292	Saccharomyces cerevisiae (S288c)	1251	13	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
119130	50813	-	COPS7A	CSN7|CSN7A|SGN7a	9606	Homo sapiens	378	59	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	CSN7a_helixI|PCI	PF18392|PF01399	-	-	-	-	-
114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	652	1	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Acetyltransf_1|Bromodomain|PCAF_N	PF00583|PF00439|PF06466	-	-	-	-	-
123125	80124	-	VCPIP1	DUBA3|VCIP135	9606	Homo sapiens	229	60	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
127317	150684	-	COMMD1	C2orf5|MURR1	9606	Homo sapiens	294	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	COMMD1_N|COMM_domain	PF17221|PF07258	-	-	-	-	-
127315	150678	-	MYEOV2	-	9606	Homo sapiens	111	2	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	MYEOV2	PF15004	-	-	-	-	-
123129	80128	RP11-263K19.1	TRIM46	GENEY|TRIFIC	9606	Homo sapiens	40	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	COS|zf-B_box|zf-RING_UBOX	PF18568|PF00643|PF13445	-	-	-	-	-
575543	653121	-	ZBTB8A	BOZF1|ZBTB8|ZNF916A	9606	Homo sapiens	138	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
31057	850445	YCR084C	TUP1	AAR1|AER2|AMM1|CRT4|CYC9|FLK1|ROX4|SFL2|UMR7|chromatin-silencing transcriptional regulator TUP1|L000002391	559292	Saccharomyces cerevisiae (S288c)	215	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Tup_N|WD40	PF08581|PF00400	-	-	-	-	-
126773	142684	LL0XNC01-250H12.1	RAB40A	RAR2|RAR2A	9606	Homo sapiens	35	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ras|SOCS_box	PF00071|PF07525	-	-	-	-	-
111384	5371	-	PML	MYL|PP8675|RNF71|TRIM19	9606	Homo sapiens	1465	116	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF3583|zf-B_box	PF12126|PF00643	-	-	-	-	-
126776	142689	RP11-284B18.4	ASB12	-	9606	Homo sapiens	37	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank|Ank_2|SOCS_box	PF00023|PF12796|PF07525	-	-	-	-	-
126775	142686	-	ASB14	-	9606	Homo sapiens	58	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
126774	142685	-	ASB15	-	9606	Homo sapiens	33	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
131544	348995	-	NUP43	bA350J20.1|p42	9606	Homo sapiens	764	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
126404	134510	-	UBLCP1	CPUB1	9606	Homo sapiens	151	19	0	BIOGRID	Proteasome	-	-	-	-	-	-	NIF|ubiquitin	PF03031|PF00240	-	-	-	-	-
31987	851485	YDL074C	BRE1	E3 ubiquitin-protein ligase BRE1	559292	Saccharomyces cerevisiae (S288c)	1597	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
131548	349136	-	WDR86	-	9606	Homo sapiens	38	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
110474	4331	-	MNAT1	CAP35|MAT1|RNF66|TFB3	9606	Homo sapiens	204	19	1	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAT1|zf-C3HC4_5	PF06391|PF17121	-	-	-	-	-
35608	855491	YNL230C	ELA1	elongin A|L000004956	559292	Saccharomyces cerevisiae (S288c)	132	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Elongin_A	PF06881	-	-	-	-	-
126794	143279	RP11-108M11.2	HECTD2	-	9606	Homo sapiens	24	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
115979	10758	RP3-487J7.3	TRAF3IP2	ACT1|C6orf2|C6orf4|C6orf5|C6orf6|CANDF8|CIKS|PSORS13	9606	Homo sapiens	105	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SEFIR	PF08357	-	-	-	-	-
113523	7737	-	RNF113A	Cwc24|RNF113|ZNF183	9606	Homo sapiens	734	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CCCH	PF00642	-	-	-	-	-
32955	852562	YBR259W	YBR259W	-	559292	Saccharomyces cerevisiae (S288c)	21	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
119625	51592	-	TRIM33	ECTO|PTC7|RFG7|TF1G|TIF1G|TIF1GAMMA|TIFGAMMA	9606	Homo sapiens	617	50	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|PHD|zf-B_box|zf-RING_UBOX	PF00439|PF00628|PF00643|PF13445	-	-	-	-	-
128737	221527	DADB-122G4.2	ZBTB12	Bat9|C6orf46|D6S59E|G10|NG35	9606	Homo sapiens	32	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
32420	851967	YDR363W-A	SEM1	DSS1|HOD1|proteasome regulatory particle lid subunit SEM1|L000003539|L000004647	559292	Saccharomyces cerevisiae (S288c)	1010	2	0	BIOGRID	Proteasome	-	-	-	-	-	-	DSS1_SEM1	PF05160	-	-	-	-	-
117954	27012	-	KCNV1	HNKA|KCNB3|KV2.3|KV8.1	9606	Homo sapiens	36	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
117950	27005	RP11-297K8.3	USP21	USP16|USP23	9606	Homo sapiens	228	38	3	BIOGRID	Deubiquitinating enzyme (DUB)|NEDD8-specific protease	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
127223	149603	-	RNF187	RACO-1|RACO1	9606	Homo sapiens	65	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4	PF00097	-	-	-	-	-
120029	54542	RP11-163B6.3	RC3H2	MNAB|RNF164	9606	Homo sapiens	764	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ROQ_II|zf-CCCH|zf-RING_UBOX	PF18386|PF00642|PF13445	-	-	-	-	-
110276	4102	-	MAGEA3	CT1.3|HIP8|HYPD|MAGE3|MAGEA6	9606	Homo sapiens	164	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110275	4101	-	MAGEA2	CT1.2|MAGE2|MAGEA2A	9606	Homo sapiens	44	25	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
120798	55666	-	NPLOC4	NPL4	9606	Homo sapiens	372	113	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	NPL4|UN_NPL4|zf-NPL4	PF05021|PF11543|PF05020	-	-	-	-	-
110279	4105	-	MAGEA6	CT1.6|MAGE-3b|MAGE3B|MAGE6	9606	Homo sapiens	121	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110278	4104	-	MAGEA5	CT1.5|MAGE5|MAGEA4	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE_N	PF12440	-	-	-	-	-
120020	54532	-	USP53	-	9606	Homo sapiens	154	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
1529114	100507650	hCG_1815045	RNF212B	C14orf164	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
120790	55658	-	RNF126	-	9606	Homo sapiens	266	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2|zinc_ribbon_9	PF13639|PF14369	-	-	-	-	-
114757	9354	-	UBE4A	E4|UBOX2|UFD2	9606	Homo sapiens	171	31	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	U-box|Ufd2P_core	PF04564|PF10408	-	-	-	-	-
114023	8445	-	DYRK2	-	9606	Homo sapiens	226	4	9	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
114028	8450	-	CUL4B	CUL-4B|MRXHF2|MRXS15|MRXSC|SFM2	9606	Homo sapiens	1355	215	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
114029	8451	RP11-391H12.1	CUL4A	-	9606	Homo sapiens	1595	209	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
114595	9148	-	NEURL1	NEUR1|NEURL|RNF67|bA416N2.1|neu|neu-1	9606	Homo sapiens	29	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Neuralized	PF07177	-	-	-	-	-
114593	9146	-	HGS	HRS	9606	Homo sapiens	800	111	1	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	FYVE|Hrs_helical|VHS	PF01363|PF12210|PF00790	-	-	-	-	-
120335	55003	RP11-421M1.5	PAK1IP1	MAK11|PIP1|WDR84|bA421M1.5|hPIP1	9606	Homo sapiens	189	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
32174	851696	YDR118W	APC4	anaphase promoting complex subunit 4|L000004319	559292	Saccharomyces cerevisiae (S288c)	144	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4	PF12896	-	-	-	-	-
120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	490	2	8	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ZNRF_3_ecto|zf-RING_2	PF18212|PF13639	-	-	-	-	-
115192	9858	RP11-426A6.6	PPP1R26	KIAA0649	9606	Homo sapiens	28	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PPP1R26_N	PF15740	-	-	-	-	-
121310	56995	RP3-442A17.1	TULP4	TUSP	9606	Homo sapiens	37	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Tub	PF01167	-	-	-	-	-
32376	851918	YDR320C	SWA2	AUX1|BUD24	559292	Saccharomyces cerevisiae (S288c)	607	24	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Ubiq-assoc	PF09145	-	-	-	-	-
117133	23598	-	PATZ1	MAZR|PATZ|RIAZ|ZBTB19|ZNF278|ZSG|dJ400N23	9606	Homo sapiens	212	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
119435	51283	-	BFAR	BAR|RNF47	9606	Homo sapiens	58	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SAM_1	PF00536	-	-	-	-	-
119920	54165	-	DCUN1D1	DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3	9606	Homo sapiens	442	103	7	BIOGRID	NEDD8 E3	-	-	-	-	-	-	Cullin_binding	PF03556	-	-	-	-	-
575963	653659	-	TMEM183B	C1orf37-DUP	9606	Homo sapiens	1	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	149	40	28	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
32633	852212	YBL067C	UBP13	L000003172	559292	Saccharomyces cerevisiae (S288c)	278	14	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
124834	91445	-	RNF185	-	9606	Homo sapiens	268	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
124301	84851	-	TRIM52	RNF102	9606	Homo sapiens	137	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box	PF00643	-	-	-	-	-
124308	84861	-	KLHL22	KELCHL	9606	Homo sapiens	250	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
116664	23024	-	PDZRN3	LNX3|SEMACAP3|SEMCAP3	9606	Homo sapiens	74	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PDZ	PF00595	-	-	-	-	-
118096	27248	UNQ1878/PRO4321	ERLEC1	C2orf30|CIM|CL24936|CL25084|HEL117|XTP3-B|XTP3TPB	9606	Homo sapiens	269	29	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	PRKCSH	PF07915	-	-	-	-	-
118094	27246	-	RNF115	BCA2|ZNF364	9606	Homo sapiens	205	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124941	92369	-	SPSB4	SSB-4|SSB4	9606	Homo sapiens	151	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box|SPRY	PF07525|PF00622	-	-	-	-	-
124238	84749	-	USP30	-	9606	Homo sapiens	184	19	2	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
128203	196403	-	DTX3	RNF154|deltex3	9606	Homo sapiens	150	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DTC	PF18102	-	-	-	-	-
36893	856887	YER144C	UBP5	L000002419	559292	Saccharomyces cerevisiae (S288c)	92	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Rhodanese|UCH	PF00581|PF00443	-	-	-	-	-
36892	856886	YER143W	DDI1	VSM1|L000004257	559292	Saccharomyces cerevisiae (S288c)	206	14	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Asp_protease|UBA	PF09668|PF00627	-	-	-	-	-
113722	8027	-	STAM	STAM-1|STAM1	9606	Homo sapiens	269	144	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SH3_1|UIM|VHS	PF00018|PF02809|PF00790	-	-	-	-	-
122067	64110	-	MAGEF1	-	9606	Homo sapiens	46	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
133800	391104	-	VHLL	VHLP|VLP	9606	Homo sapiens	9	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	VHL	PF01847	-	-	-	-	-
570429	645402	-	USP17L4	-	9606	Homo sapiens	0	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
33111	852736	YGL141W	HUL5	ubiquitin-ubiquitin ligase HUL5	559292	Saccharomyces cerevisiae (S288c)	100	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	531	185	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|SAD_SRA|TTD|ubiquitin	PF00628|PF02182|PF12148|PF00240	-	-	-	-	-
118895	29761	-	USP25	USP21	9606	Homo sapiens	223	306	1	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UCH|UIM	PF00443|PF02809	-	-	-	-	-
125120	94121	RP11-524D16__A.2	SYTL4	SLP4	9606	Homo sapiens	122	50	7	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|FYVE_2	PF00168|PF02318	-	-	-	-	-
36413	856376	YHL010C	ETP1	BRP2	559292	Saccharomyces cerevisiae (S288c)	89	30	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BRAP2|zf-RING_2|zf-UBP	PF07576|PF13639|PF02148	-	-	-	-	-
36410	856373	YHL013C	OTU2	-	559292	Saccharomyces cerevisiae (S288c)	201	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
113836	8193	-	DPF1	BAF45b|NEUD4|neuro-d4	9606	Homo sapiens	157	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|Requiem_N	PF00628|PF14051	-	-	-	-	-
119981	54476	-	RNF216	CAHH|TRIAD3|U7I1|UBCE7IP1|ZIN	9606	Homo sapiens	92	171	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121683	57646	-	USP28	-	9606	Homo sapiens	192	377	3	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
121680	57643	RP11-69J16.3	ZSWIM5	-	9606	Homo sapiens	7	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
32149	851666	YDR092W	UBC13	E2  ubiquitin-conjugating protein UBC13|L000003387	559292	Saccharomyces cerevisiae (S288c)	419	3	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
36673	856654	YEL056W	HAT2	L000003400	559292	Saccharomyces cerevisiae (S288c)	148	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40	PF12265|PF00400	-	-	-	-	-
134027	391712	-	TRIM61	RNF35	9606	Homo sapiens	12	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box	PF00643	-	-	-	-	-
33756	853456	YJL001W	PRE3	CRL21|proteasome core particle subunit beta 1|L000000418|L000001485	559292	Saccharomyces cerevisiae (S288c)	271	12	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
122886	79786	-	KLHL36	C16orf44	9606	Homo sapiens	105	20	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
33247	852886	YGR003W	CUL3	cullin CUL3|CULLIN B|CULB	559292	Saccharomyces cerevisiae (S288c)	146	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
33241	852880	YGL004C	RPN14	-	559292	Saccharomyces cerevisiae (S288c)	168	1	0	BIOGRID	Proteasome	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
33242	852881	YGL003C	CDH1	HCT1|L000004229	559292	Saccharomyces cerevisiae (S288c)	662	35	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40	PF12894|PF00400	-	-	-	-	-
123686	83590	SB144	TMUB1	C7orf21|DULP	9606	Homo sapiens	175	7	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
122243	64718	LA16c-316G12.1	UNKL	C16orf28|ZC3H5L|ZC3HDC5L	9606	Homo sapiens	81	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-CCCH|zf_CCCH_5	PF00642|PF18384	-	-	-	-	-
36350	856307	YPR178W	PRP4	RNA4|L000001497	559292	Saccharomyces cerevisiae (S288c)	841	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
122532	79084	HKMT1069	WDR77	MEP-50|MEP50|Nbla10071|p44|p44/Mep50	9606	Homo sapiens	568	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
138966	494470	-	RNF165	ARKL2|RNF111L2	9606	Homo sapiens	19	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
122084	64145	-	RBSN	Rabenosyn-5|ZFYVE20	9606	Homo sapiens	108	12	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	FYVE|Rbsn	PF01363|PF11464	-	-	-	-	-
116705	23072	-	HECW1	NEDL1	9606	Homo sapiens	47	94	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|HECW1_helix|HECW_N|WW	PF00168|PF00632|PF18436|PF16562|PF00397	-	-	-	-	-
115769	10513	-	APPBP2	APP-BP2|HS.84084|PAT1	9606	Homo sapiens	276	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
34921	854739	YIL071C	PCI8	CSN11|YIH1|YIL071W|S000007580	559292	Saccharomyces cerevisiae (S288c)	121	0	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	-	-	-	-	-	-	-
122960	79872	-	CBLL1	HAKAI|RNF188	9606	Homo sapiens	102	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf_Hakai	PF18408	-	-	-	-	-
109340	3093	-	UBE2K	E2-25K|HIP2|HYPG|LIG|UBC1	9606	Homo sapiens	261	40	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UBA|UQ_con	PF00627|PF00179	-	-	-	-	-
115508	10213	-	PSMD14	PAD1|POH1|RPN11	9606	Homo sapiens	1082	22	2	BIOGRID	Deubiquitinating enzyme (DUB)|Proteasome	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
109349	3104	RP11-58A11.4	ZBTB48	HKR3|ZNF855|pp9964	9606	Homo sapiens	211	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
35276	855126	YMR100W	MUB1	L000004359	559292	Saccharomyces cerevisiae (S288c)	428	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-MYND	PF01753	-	-	-	-	-
126542	139081	RP6-232G24.3	MAGEC3	CT7.2|HCA2|MAGE-C3|MAGEC4	9606	Homo sapiens	11	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
115501	10206	-	TRIM13	CAR|DLEU5|LEU5|RFP2|RNF77	9606	Homo sapiens	209	45	15	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
117142	23609	HSPC070	MKRN2	RNF62	9606	Homo sapiens	472	35	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4|zf-CCCH|zf-CCCH_4	PF00097|PF00642|PF18044	-	-	-	-	-
115505	10210	RP11-205M20.5	TOPORS	LUN|P53BP3|RP31|TP53BPL	9606	Homo sapiens	160	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
123205	80263	RP11-229A19.2	TRIM45	RNF99	9606	Homo sapiens	48	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Filamin|zf-B_box|zf-RING_UBOX	PF00630|PF00643|PF13445	-	-	-	-	-
123207	80267	-	EDEM3	C1orf22	9606	Homo sapiens	204	17	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Glyco_hydro_47|PA	PF01532|PF02225	-	-	-	-	-
33806	853512	YJR052W	RAD7	UV-damaged DNA-binding protein RAD7|L000001561	559292	Saccharomyces cerevisiae (S288c)	183	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
123751	83743	-	GRWD1	CDW4|GRWD|RRB1|WDR28	9606	Homo sapiens	479	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40	PF12265|PF00400	-	-	-	-	-
108564	2273	RP11-535K18.1	FHL1	FHL-1|FHL1A|FHL1B|FLH1A|KYOT|SLIM|SLIM-1|SLIM1|SLIMMER|XMPMA	9606	Homo sapiens	220	269	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LIM	PF00412	-	-	-	-	-
106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	1513	18	20	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR|CARD	PF00653|PF00619	-	-	-	-	-
106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	620	66	88	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR|CARD	PF00653|PF00619	-	-	-	-	-
106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	740	90	73	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR	PF00653	-	-	-	-	-
114968	9604	HRIHFB2038	RNF14	ARA54|HFB30|TRIAD2	9606	Homo sapiens	78	90	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR|RWD	PF01485|PF05773	-	-	-	-	-
115217	9886	-	RHOBTB1	-	9606	Homo sapiens	467	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Ras	PF00651|PF00071	-	-	-	-	-
115211	9880	-	ZBTB39	ZNF922	9606	Homo sapiens	38	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	735	15	9	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase|UBA	PF00069|PF00627	-	-	-	-	-
34109	853846	YKL022C	CDC16	anaphase promoting complex subunit CDC16|L000000256	559292	Saccharomyces cerevisiae (S288c)	444	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TPR_2|TPR_8	PF07719|PF13181	-	-	-	-	-
128878	246184	-	CDC26	ANAPC12|APC12|C9orf17	9606	Homo sapiens	147	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC_CDC26	PF10471	-	-	-	-	-
114362	8835	-	SOCS2	CIS2|Cish2|SOCS-2|SSI-2|SSI2|STATI2	9606	Homo sapiens	206	1	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS_box	PF00017|PF07525	-	-	-	-	-
110865	4799	-	NFX1	NFX2|TEG-42|Tex42	9606	Homo sapiens	509	77	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	R3H|zf-NF-X1	PF01424|PF01422	-	-	-	-	-
126432	135644	DAAP-200B17.3	TRIM40	RNF35	9606	Homo sapiens	108	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_UBOX	PF13445	-	-	-	-	-
126435	135892	-	TRIM50	TRIM50A	9606	Homo sapiens	82	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box|zf-RING_UBOX	PF13765|PF00622|PF00643|PF13445	-	-	-	-	-
35618	855503	YNL218W	MGS1	ssDNA-dependent ATPase MGS1	559292	Saccharomyces cerevisiae (S288c)	134	2	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	AAA|AAA_assoc_2|MgsA_C	PF00004|PF16193|PF12002	-	-	-	-	-
117727	26524	-	LATS2	KPM	9606	Homo sapiens	484	14	2	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase|Pkinase_C	PF00069|PF00433	-	-	-	-	-
119162	50862	-	RNF141	ZFP26|ZNF230	9606	Homo sapiens	15	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
35349	855207	YMR171C	EAR1	-	559292	Saccharomyces cerevisiae (S288c)	88	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
115989	10771	RP11-486H9.1	ZMYND11	BRAM1|BS69|MRD30	9606	Homo sapiens	146	235	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|PWWP	PF00439|PF00855	-	-	-	-	-
114103	8533	-	COPS3	CSN3|SGN3	9606	Homo sapiens	535	185	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	PCI	PF01399	-	-	-	-	-
34747	854544	YOR362C	PRE10	proteasome core particle subunit alpha 7|L000003146	559292	Saccharomyces cerevisiae (S288c)	780	8	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
35296	855147	YMR119W	ASI1	putative ubiquitin-protein ligase ASI1	559292	Saccharomyces cerevisiae (S288c)	125	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
32967	852575	YBR272C	HSM3	L000004729	559292	Saccharomyces cerevisiae (S288c)	255	3	0	BIOGRID	Proteasome	-	-	-	-	-	-	HSM3_C|HSM3_N	PF18794|PF18795	-	-	-	-	-
119655	51646	CGI-127	YPEL5	-	9606	Homo sapiens	152	28	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Yippee-Mis18	PF03226	-	-	-	-	-
32418	851965	YDR363W	ESC2	L000004423	559292	Saccharomyces cerevisiae (S288c)	543	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Rad60-SLD	PF11976	-	-	-	-	-
32414	851960	YDR358W	GGA1	S000007493	559292	Saccharomyces cerevisiae (S288c)	196	20	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Alpha_adaptinC2|GAT|GGA_N-GAT|VHS	PF02883|PF03127|PF18308|PF00790	-	-	-	-	-
32984	852593	YBR290W	BSD2	L000000194	559292	Saccharomyces cerevisiae (S288c)	276	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF2370	PF10176	-	-	-	-	-
110288	4114	-	MAGEB3	CT3.5	9606	Homo sapiens	8	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110289	4115	-	MAGEB4	CT3.6	9606	Homo sapiens	79	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110286	4112	-	MAGEB1	CT3.1|DAM10|MAGE-Xp|MAGEL1	9606	Homo sapiens	11	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110287	4113	-	MAGEB2	CT3.2|DAM6|MAGE-XP-2	9606	Homo sapiens	413	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110284	4110	-	MAGEA11	CT1.11|MAGE-11|MAGE11|MAGEA-11	9606	Homo sapiens	236	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110285	4111	-	MAGEA12	CT1.12|MAGE12	9606	Homo sapiens	40	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110282	4108	-	MAGEA9	CT1.9|MAGE9	9606	Homo sapiens	225	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE_N	PF12440	-	-	-	-	-
110283	4109	-	MAGEA10	CT1.10|MAGE10	9606	Homo sapiens	196	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
110281	4107	-	MAGEA8	CT1.8|MAGE8	9606	Homo sapiens	155	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
117039	23480	-	SEC61G	SSS1	9606	Homo sapiens	48	3	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	SecE	PF00584	-	-	-	-	-
114031	8453	RP11-297A16.3	CUL2	-	9606	Homo sapiens	1028	134	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
114030	8452	-	CUL3	CUL-3|PHA2E	9606	Homo sapiens	4893	210	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
114032	8454	-	CUL1	-	9606	Homo sapiens	1954	172	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
110912	4850	-	CNOT4	CLONE243|NOT4|NOT4H	9606	Homo sapiens	107	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RRM_1	PF00076	-	-	-	-	-
127431	152137	-	CCDC50	C3orf6|DFNA44|YMER	9606	Homo sapiens	99	80	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CCDC50_N	PF15295	-	-	-	-	-
131888	374286	-	CDRT1	C170RF1|C17ORF1|C17ORF1A|FBXW10B|FBXW10P1|HREP|SM25H2	9606	Homo sapiens	2	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
120474	55175	-	KLHL11	-	9606	Homo sapiens	97	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120475	55176	-	SEC61A2	-	9606	Homo sapiens	59	25	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Plug_translocon|SecY	PF10559|PF00344	-	-	-	-	-
32188	851710	YDR132C	YDR132C	-	559292	Saccharomyces cerevisiae (S288c)	80	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
121301	56984	-	PSMG2	CLAST3|HCCA3|HsT1707|MDS003|PAC2|TNFSF5IP1	9606	Homo sapiens	168	15	0	BIOGRID	Proteasome	-	-	-	-	-	-	PAC2	PF09754	-	-	-	-	-
138138	442247	-	RFPL4B	RNF211	9606	Homo sapiens	108	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
126237	130507	-	UBR3	ZNF650	9606	Homo sapiens	179	83	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRT6_C|zf-UBR	PF18995|PF02207	-	-	-	-	-
119424	51271	RP11-571F15.1	UBAP1	NAG20|UAP|UBAP|UBAP-1	9606	Homo sapiens	79	121	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
128522	219333	-	USP12	UBH1|USP12L1	9606	Homo sapiens	165	2	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
124047	84321	-	THOC3	THO3|hTREX45	9606	Homo sapiens	206	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40|eIF2A	PF12894|PF00400|PF08662	-	-	-	-	-
116856	23252	RP11-460G22.1	OTUD3	DUBA4	9606	Homo sapiens	86	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
125796	122809	-	SOCS4	SOCS7	9606	Homo sapiens	34	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS|SOCS_box	PF00017|PF12610|PF07525	-	-	-	-	-
116183	10987	-	COPS5	CSN5|JAB1|MOV-34|SGN5	9606	Homo sapiens	1724	23	1	BIOGRID	Deubiquitinating enzyme (DUB)|NEDD8-specific protease	-	-	-	-	-	-	CSN5_C|JAB	PF18323|PF01398	-	-	-	-	-
125793	122769	-	LRR1	4-1BBLRR|LRR-1|PPIL5	9606	Homo sapiens	89	18	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_4	PF12799	-	-	-	-	-
116671	23032	-	USP33	VDU1	9606	Homo sapiens	240	257	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|UCH|zf-UBP	PF06337|PF00443|PF02148	-	-	-	-	-
36085	856009	YPL096W	PNG1	-	559292	Saccharomyces cerevisiae (S288c)	88	29	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Rad4	PF03835	-	-	-	-	-
116677	23038	RP11-4K3__A.1	WDTC1	ADP|DCAF9	9606	Homo sapiens	242	31	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
36719	856704	YEL012W	UBC8	GID3|E2 ubiquitin-conjugating protein UBC8|L000002410	559292	Saccharomyces cerevisiae (S288c)	148	1	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
570781	645836	-	USP17L3	USP17B|USP17F	9606	Homo sapiens	6	2	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
128238	197131	-	UBR1	JBS	9606	Homo sapiens	391	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ClpS|PRT6_C|zf-UBR	PF02617|PF18995|PF02207	-	-	-	-	-
124954	92552	-	ATXN3L	MJDL	9606	Homo sapiens	22	0	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Josephin|UIM	PF02099|PF02809	-	-	-	-	-
124227	84727	-	SPSB2	GRCC9|SSB2	9606	Homo sapiens	95	2	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box|SPRY	PF07525|PF00622	-	-	-	-	-
124958	92591	-	ASB16	-	9606	Homo sapiens	41	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
36755	856742	YER021W	RPN3	SUN2|proteasome regulatory particle lid subunit RPN3|L000003109	559292	Saccharomyces cerevisiae (S288c)	350	5	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|Rpn3_C	PF01399|PF08375	-	-	-	-	-
113221	7375	-	USP4	UNP|Unph	9606	Homo sapiens	448	47	3	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|UCH|Ubiquitin_3	PF06337|PF00443|PF14836	-	-	-	-	-
116077	10868	-	USP20	LSFR3A|VDU2|hVDU2	9606	Homo sapiens	289	53	3	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DUSP|UCH|zf-UBP	PF06337|PF00443|PF02148	-	-	-	-	-
116078	10869	-	USP19	ZMYND9	9606	Homo sapiens	247	318	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	CS|UCH|zf-MYND	PF04969|PF00443|PF01753	-	-	-	-	-
107574	1154	-	CISH	BACTS2|CIS|CIS-1|G18|SOCS	9606	Homo sapiens	62	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS_box	PF00017|PF07525	-	-	-	-	-
116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	1805	82	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
36458	856422	YHR027C	RPN1	HRD2|NAS1|proteasome regulatory particle base subunit RPN1|L000003039	559292	Saccharomyces cerevisiae (S288c)	1197	64	0	BIOGRID	Proteasome	-	-	-	-	-	-	PC_rep|RPN1_C|RPN1_RPN2_N	PF01851|PF18051|PF17781	-	-	-	-	-
120877	55759	-	WDR12	YTM1	9606	Homo sapiens	195	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	NLE|WD40	PF08154|PF00400	-	-	-	-	-
115301	9978	RP11-554C12.1	RBX1	BA554C12.1|RNF75|ROC1	9606	Homo sapiens	1541	5	1	BIOGRID	NEDD8 E3|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-rbx1	PF12678	-	-	-	-	-
113647	7917	DADB-70P7.10-021	BAG6	BAG-6|BAT3|D6S52E|G3	9606	Homo sapiens	727	382	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	BAG6|ubiquitin	PF12057|PF00240	-	-	-	-	-
122435	65986	-	ZBTB10	RINZF	9606	Homo sapiens	182	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
118842	29068	-	ZBTB44	BTBD15|HSPC063|ZNF851	9606	Homo sapiens	84	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
123921	84164	SC22CB-11B7.2	ASCC2	ASC1p100|p100	9606	Homo sapiens	179	220	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
121694	57661	-	PHRF1	PPP1R125|RNF221	9606	Homo sapiens	79	90	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|zf-RING_2	PF00628|PF13639	-	-	-	-	-
121696	57663	-	USP29	HOM-TES-84/86	9606	Homo sapiens	77	0	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|UCH_N	PF00443|PF16674	-	-	-	-	-
121693	57659	-	ZBTB4	KAISO-L1|ZNF903	9606	Homo sapiens	40	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
126578	139604	RP11-497J7.3	MAGEB16	-	9606	Homo sapiens	3	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
939139	100287478	-	USP17L21	-	9606	Homo sapiens	5	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
114439	8925	-	HERC1	p532|p619	9606	Homo sapiens	229	97	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|RCC1|SPRY|WD40	PF00632|PF00415|PF00622|PF00400	-	-	-	-	-
123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	197	18	7	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C2H2	PF00096	-	-	-	-	-
608244	727800	-	RNF208	-	9606	Homo sapiens	76	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
940177	100288520	-	USP17L15	-	9606	Homo sapiens	3	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
938840	100287178	-	USP17L11	-	9606	Homo sapiens	5	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
122506	79047	-	KCTD15	-	9606	Homo sapiens	91	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
113912	8315	-	BRAP	BRAP2|IMP|RNF52	9606	Homo sapiens	138	50	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BRAP2|zf-RING_2|zf-UBP	PF07576|PF13639|PF02148	-	-	-	-	-
113911	8314	hucep-6	BAP1	HUCEP-13|UCHL2	9606	Homo sapiens	1667	23	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C12|UCH_C	PF01088|PF18031	-	-	-	-	-
115772	10517	-	FBXW10	Fbw10|HREP|SM25H2|SM2SH2	9606	Homo sapiens	141	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
31278	850691	YLR005W	SSL1	TFIIH/NER complex subunit SSL1|L000002085	559292	Saccharomyces cerevisiae (S288c)	634	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C1_4|Ssl1	PF07975|PF04056	-	-	-	-	-
123747	83737	-	ITCH	ADMFD|AIF4|AIP4|NAPP1|dJ468O1.1	9606	Homo sapiens	823	163	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
35992	855910	YPL191C	YPL191C	-	559292	Saccharomyces cerevisiae (S288c)	82	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	MINDY_DUB	PF04424	-	-	-	-	-
31677	851137	YLR419W	YLR419W	putative helicase	559292	Saccharomyces cerevisiae (S288c)	132	10	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DEAD|HA2|Helicase_C|OB_NTP_bind|RWD	PF00270|PF04408|PF00271|PF07717|PF05773	-	-	-	-	-
31675	851135	YLR417W	VPS36	GRD12|VAC3|VPL11|ESCRT-II subunit protein VPS36|L000002958	559292	Saccharomyces cerevisiae (S288c)	223	1	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EAP30|Vps36-NZF-N|Vps36_ESCRT-II	PF04157|PF16988|PF11605	-	-	-	-	-
106764	267	-	AMFR	GP78|RNF45	9606	Homo sapiens	587	26	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CUE|G2BR|zf-RING_2	PF02845|PF18442|PF13639	-	-	-	-	-
112770	6907	-	TBL1X	EBI|SMAP55|TBL1	9606	Homo sapiens	250	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LisH|WD40	PF08513|PF00400	-	-	-	-	-
34242	853986	YOL133W	HRT1	HRT2|RBX1|ROC1|SCF ubiquitin ligase complex subunit HRT1|L000004443	559292	Saccharomyces cerevisiae (S288c)	178	3	0	BIOGRID	NEDD8 E3|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-rbx1	PF12678	-	-	-	-	-
115177	9841	-	ZBTB24	BIF1|ICF2|PATZ2|ZNF450	9606	Homo sapiens	203	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
35197	855040	YMR025W	CSI1	S000028416	559292	Saccharomyces cerevisiae (S288c)	183	0	0	BIOGRID	NEDD8-specific protease	-	-	-	-	-	-	-	-	-	-	-	-	-
35193	855036	YMR022W	UBC7	DER2|QRI8|E2 ubiquitin-conjugating protein UBC7|L000001552	559292	Saccharomyces cerevisiae (S288c)	529	2	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
115200	9867	-	PJA2	Neurodap1|RNF131	9606	Homo sapiens	210	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
115203	9870	-	AREL1	KIAA0317	9606	Homo sapiens	68	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Filamin|HECT	PF00630|PF00632	-	-	-	-	-
31417	850840	YLR148W	PEP3	VAM8|VPS18|VPT18|tethering complex subunit PEP3|L000001374|L000002473	559292	Saccharomyces cerevisiae (S288c)	209	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Clathrin|Pep3_Vps18	PF00637|PF05131	-	-	-	-	-
35198	855041	YMR026C	PEX12	PAS11|ubiquitin-protein ligase peroxin 12|L000004223|L000003964	559292	Saccharomyces cerevisiae (S288c)	415	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12	PF04757	-	-	-	-	-
115195	9861	-	PSMD6	Rpn7|S10|SGA-113M|p42A|p44S10	9606	Homo sapiens	628	112	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|RPN7	PF01399|PF10602	-	-	-	-	-
108374	2060	-	EPS15	AF-1P|AF1P|MLLT5	9606	Homo sapiens	411	183	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EF-hand_4	PF12763	-	-	-	-	-
108173	1840	-	DTX1	hDx-1	9606	Homo sapiens	49	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DTC|WWE|zf-C3HC4	PF18102|PF02825|PF00097	-	-	-	-	-
32900	852502	YBR203W	COS111	-	559292	Saccharomyces cerevisiae (S288c)	108	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111656	5683	-	PSMA2	HC3|MU|PMSA2|PSC2	9606	Homo sapiens	631	16	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
111657	5684	-	PSMA3	HC8|PSC3	9606	Homo sapiens	793	36	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
123596	81844	-	TRIM56	RNF109	9606	Homo sapiens	197	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
111655	5682	-	PSMA1	HC2|HEL-S-275|NU|PROS30	9606	Homo sapiens	941	33	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
111658	5685	-	PSMA4	HC9|HsT17706|PSC9	9606	Homo sapiens	849	137	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
111659	5686	-	PSMA5	PSC5|ZETA	9606	Homo sapiens	638	40	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
31306	850719	YLR032W	RAD5	REV2|SNM2|DNA helicase RAD5|L000001559	559292	Saccharomyces cerevisiae (S288c)	816	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HIRAN|Helicase_C|SNF2_N|zf-RING_2	PF08797|PF00271|PF00176|PF13639	-	-	-	-	-
127931	166655	-	TRIM60	RNF129|RNF33	9606	Homo sapiens	5	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
127934	166793	-	ZBTB49	ZNF509	9606	Homo sapiens	42	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
127688	158506	-	ZNF645	CT138|HAKAIL	9606	Homo sapiens	33	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf_Hakai	PF18408	-	-	-	-	-
115991	10773	-	ZBTB6	ZID|ZNF482	9606	Homo sapiens	16	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
114979	9618	-	TRAF4	CART1|MLN62|RNF83	9606	Homo sapiens	339	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4|zf-TRAF	PF00097|PF02176	-	-	-	-	-
119641	51619	-	UBE2D4	HBUCE1	9606	Homo sapiens	188	5	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
32974	852583	YBR280C	SAF1	SCF ubiquitin ligase complex subunit SAF1	559292	Saccharomyces cerevisiae (S288c)	57	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
132764	388591	-	RNF207	C1orf188	9606	Homo sapiens	386	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-C3HC4	PF00643|PF00097	-	-	-	-	-
119647	51633	CGI-77	OTUD6B	DUBA-5|DUBA5	9606	Homo sapiens	160	14	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
32977	852586	YBR283C	SSH1	L000003994	559292	Saccharomyces cerevisiae (S288c)	628	1	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Plug_translocon|SecY	PF10559|PF00344	-	-	-	-	-
32196	851720	YDR142C	PEX7	PAS7|PEB1|L000001340	559292	Saccharomyces cerevisiae (S288c)	127	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
110678	4591	-	TRIM37	MUL|POB1|TEF3	9606	Homo sapiens	747	175	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MATH|zf-B_box	PF00917|PF00643	-	-	-	-	-
107985	1616	DADB-159G18.9	DAXX	BING2|DAP6|EAP1	9606	Homo sapiens	790	83	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Daxx	PF03344	-	-	-	-	-
116510	22836	-	RHOBTB3	-	9606	Homo sapiens	189	74	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Ras	PF00651|PF00071	-	-	-	-	-
116512	22838	-	RNF44	-	9606	Homo sapiens	16	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
35578	855460	YNL261W	ORC5	origin recognition complex subunit 5|L000002814	559292	Saccharomyces cerevisiae (S288c)	255	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	AAA_22|ORC5_C	PF13401|PF14630	-	-	-	-	-
120481	55182	RP4-678E16.1	RNF220	C1orf164	9606	Homo sapiens	64	61	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RNF220	PF15926	-	-	-	-	-
120485	55187	-	VPS13D	-	9606	Homo sapiens	88	23	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Chorein_N|SHR-BD|UBA|VPS13|VPS13_C|VPS13_mid_rpt	PF12624|PF06650|PF00627|PF16908|PF16909|PF16910	-	-	-	-	-
127116	148066	-	ZNRF4	RNF204|SPERIZIN|Ssrzf1|spzn	9606	Homo sapiens	265	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
35401	855263	YMR223W	UBP8	ubiquitin-specific protease UBP8|L000004587	559292	Saccharomyces cerevisiae (S288c)	987	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|zf-UBP	PF00443|PF02148	-	-	-	-	-
127449	152518	-	NFXL1	CDZFP|HOZFP|OZFP|URCC5	9606	Homo sapiens	175	118	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-NF-X1	PF01422	-	-	-	-	-
120467	55167	-	MSL2	MSL-2|MSL2L1|RNF184	9606	Homo sapiens	75	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MSL2-CXC|zf-RING_10	PF16682|PF16685	-	-	-	-	-
120460	55159	-	RFWD3	RNF201	9606	Homo sapiens	149	113	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124146	84614	-	ZBTB37	D430004I08Rik|ZNF908	9606	Homo sapiens	7	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
32197	851721	YDR143C	SAN1	ubiquitin-protein ligase SAN1|L000001800	559292	Saccharomyces cerevisiae (S288c)	272	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
32193	851717	YDR139C	RUB1	NEDD8 family protein RUB1|L000003330|L000004485	559292	Saccharomyces cerevisiae (S288c)	110	4	0	BIOGRID	NEDD8	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
32358	851900	YDR306C	YDR306C	-	559292	Saccharomyces cerevisiae (S288c)	71	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
117443	25948	CGI-73	KBTBD2	BKLHD1	9606	Homo sapiens	31	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
130617	337867	RP11-178C10.1	UBAC2	PHGDHL1	9606	Homo sapiens	304	4	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA	PF00627	-	-	-	-	-
35409	855271	YMR231W	PEP5	END1|VAM1|VPL9|VPS11|VPT11|tethering complex subunit PEP5|L000001376|L000002957	559292	Saccharomyces cerevisiae (S288c)	218	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	VPS11_C	PF12451	-	-	-	-	-
32353	851895	YDR301W	CFT1	YHH1|L000003600	559292	Saccharomyces cerevisiae (S288c)	220	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CPSF_A	PF03178	-	-	-	-	-
124816	91319	-	DERL3	C22orf14|IZP6|LLN2|derlin-3	9606	Homo sapiens	31	0	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	DER1	PF04511	-	-	-	-	-
128825	223082	-	ZNRF2	RNF202	9606	Homo sapiens	91	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
119411	51255	HSPC238	RNF181	-	9606	Homo sapiens	183	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
119413	51257	HSPC240	MARCH2	MARCH-II|RNF172	9606	Homo sapiens	110	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
125816	123103	-	KLHL33	-	9606	Homo sapiens	40	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|Kelch_1	PF07707|PF01344	-	-	-	-	-
31475	850904	YLR207W	HRD3	ubiquitin ligase complex subunit HRD3|L000003040	559292	Saccharomyces cerevisiae (S288c)	249	10	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Sel1	PF08238	-	-	-	-	-
134457	399939	-	TRIM49D1	TRIM49D|TRIM49D1P|TRIM49DP	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
124491	85363	-	TRIM5	RNF88|TRIM5alpha	9606	Homo sapiens	163	105	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box|zf-RING_UBOX	PF00622|PF00643|PF13445	-	-	-	-	-
125789	122706	-	PSMB11	BETA5T	9606	Homo sapiens	8	0	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
125819	123228	FKSG8	SENP8	DEN1|NEDP1|PRSC2	9606	Homo sapiens	49	0	1	BIOGRID	Deubiquitinating enzyme (DUB)|NEDD8-specific protease	-	-	-	-	-	-	Peptidase_C48	PF02902	-	-	-	-	-
116887	23291	-	FBXW11	BTRC2|BTRCP2|FBW1B|FBXW1B|Fbw11|Hos	9606	Homo sapiens	1003	36	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Beta-TrCP_D|F-box-like|WD40	PF12125|PF12937|PF00400	-	-	-	-	-
128792	222235	-	FBXL13	Fbl13	9606	Homo sapiens	45	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_6	PF13516	-	-	-	-	-
128798	222484	-	LNX2	PDZRN1	9606	Homo sapiens	148	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PDZ	PF00595	-	-	-	-	-
113038	7186	-	TRAF2	MGC:45012|TRAP|TRAP3	9606	Homo sapiens	2194	140	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TRAF_BIRC3_bd|zf-C3HC4|zf-TRAF	PF16673|PF00097|PF02176	-	-	-	-	-
113039	7187	-	TRAF3	CAP-1|CAP1|CD40bp|CRAF1|IIAE5|LAP1	9606	Homo sapiens	557	70	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-TRAF	PF02176	-	-	-	-	-
113037	7185	-	TRAF1	EBI6|MGC:10353	9606	Homo sapiens	541	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TRAF_BIRC3_bd	PF16673	-	-	-	-	-
36276	856225	YPR109W	YPR109W	-	559292	Saccharomyces cerevisiae (S288c)	146	1	0	BIOGRID	Endosome and golgi-associated degradation (EGAD)	-	-	-	-	-	-	DUF1746	PF08508	-	-	-	-	-
36274	856223	YPR108W	RPN7	proteasome regulatory particle lid subunit RPN7|L000004307	559292	Saccharomyces cerevisiae (S288c)	824	10	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|RPN7	PF01399|PF10602	-	-	-	-	-
120266	54926	RP11-176F3.4	UBE2R2	CDC34B|E2-CDC34B|UBC3B	9606	Homo sapiens	101	39	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
135145	401551	RP11-175D17.5	WDR38	-	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
124969	92703	-	TMEM183A	C1orf37	9606	Homo sapiens	33	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
124780	90933	-	TRIM41	RINCK	9606	Homo sapiens	304	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
124783	90957	-	DHX57	DDX57	9606	Homo sapiens	363	26	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DEAD|HA2|Helicase_C|OB_NTP_bind|RWD|zf-CCCH_4	PF00270|PF04408|PF00271|PF07717|PF05773|PF18044	-	-	-	-	-
116243	11059	-	WWP1	AIP5|Tiul1|hSDRP1	9606	Homo sapiens	448	69	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
116244	11060	-	WWP2	AIP2|WWp2-like	9606	Homo sapiens	1190	79	11	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT|WW	PF00632|PF00397	-	-	-	-	-
120861	55743	-	CHFR	RNF116|RNF196	9606	Homo sapiens	113	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FHA|zf-CCHH|zf-CRD	PF00498|PF10283|PF17979	-	-	-	-	-
116249	11065	RP3-447F3.1	UBE2C	UBCH10|dJ447F3.2	9606	Homo sapiens	216	40	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
33135	852762	YGL116W	CDC20	PAC5|ubiquitin-protein transferase activating protein CDC20|L000000259	559292	Saccharomyces cerevisiae (S288c)	1469	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40	PF12894	-	-	-	-	-
133620	390594	hCG_1645727	KBTBD13	HCG1645727|NEM6	9606	Homo sapiens	2	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Kelch_1	PF00651|PF01344	-	-	-	-	-
128647	220441	-	RNF152	-	9606	Homo sapiens	50	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_5	PF14634	-	-	-	-	-
128317	200312	-	RNF215	-	9606	Homo sapiens	10	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
113102	7251	-	TSG101	TSG10|VPS23	9606	Homo sapiens	591	23	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UEV|Vps23_core	PF05743|PF09454	-	-	-	-	-
33484	853147	YGR232W	NAS6	-	559292	Saccharomyces cerevisiae (S288c)	257	2	0	BIOGRID	Proteasome	-	-	-	-	-	-	Ank_2	PF12796	-	-	-	-	-
118858	29089	HSPC150	UBE2T	PIG50	9606	Homo sapiens	152	31	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
123911	84142	UNQ496/PRO1013	FAM175A	ABRA1|CCDC98	9606	Homo sapiens	176	43	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
118855	29086	HSPC142	BABAM1	C19orf62|MERIT40|NBA1	9606	Homo sapiens	231	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
125369	114818	-	KLHL29	KBTBD9	9606	Homo sapiens	48	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
113692	7979	-	SHFM1	DSS1|ECD|SEM1|SHFD1|SHSF1|Shfdg1	9606	Homo sapiens	225	3	0	BIOGRID	Proteasome	-	-	-	-	-	-	DSS1_SEM1	PF05160	-	-	-	-	-
34836	854650	YIL156W	UBP7	L000003169	559292	Saccharomyces cerevisiae (S288c)	127	6	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
125363	114803	RP4-592A1.1	MYSM1	2A-DUB|2ADUB	9606	Homo sapiens	67	83	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	JAB|Myb_DNA-binding|SWIRM	PF01398|PF00249|PF04433	-	-	-	-	-
125364	114804	-	RNF157	-	9606	Homo sapiens	57	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121427	57178	RP11-519K18.1	ZMIZ1	MIZ|RAI17|TRAFIP10|ZIMP10|hZIMP10	9606	Homo sapiens	59	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Zmiz1_N|zf-MIZ	PF18028|PF02891	-	-	-	-	-
36692	856674	YEL037C	RAD23	L000001568	559292	Saccharomyces cerevisiae (S288c)	547	30	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|XPC-binding|ubiquitin	PF00627|PF09280|PF00240	-	-	-	-	-
113743	8065	-	CUL5	VACM-1|VACM1	9606	Homo sapiens	1049	37	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
33000	852611	YGL240W	DOC1	APC10|anaphase promoting complex subunit DOC1|L000004350	559292	Saccharomyces cerevisiae (S288c)	338	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC10	PF03256	-	-	-	-	-
112615	6737	-	TRIM21	RNF81|RO52|Ro/SSA|SSA|SSA1	9606	Homo sapiens	998	11	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
138947	494188	-	FBXO47	-	9606	Homo sapiens	3	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box	PF00646	-	-	-	-	-
112162	6248	-	RSC1A1	RS1	9606	Homo sapiens	18	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	-	-	-	-	-	-	-
115691	10422	RP11-432J22.3	UBAC1	GBDR1|UBADC1	9606	Homo sapiens	189	20	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA	PF00627	-	-	-	-	-
115694	10425	HT005	ARIH2	ARI2|TRIAD1	9606	Homo sapiens	405	328	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
112983	7128	RP11-356I2.3	TNFAIP3	A20|OTUD7C|TNFA1P2	9606	Homo sapiens	454	92	0	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	OTU|zf-A20	PF02338|PF01754	-	-	-	-	-
125217	112939	-	NACC1	BEND8|BTBD14B|BTBD30|NAC-1|NAC1	9606	Homo sapiens	144	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BEN|BTB	PF10523|PF00651	-	-	-	-	-
125219	112950	RP1-92O14.5	MED8	ARC32	9606	Homo sapiens	282	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Med8	PF10232	-	-	-	-	-
115740	10477	-	UBE2E3	UBCH9|UbcM2	9606	Homo sapiens	244	55	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
33312	852960	YGR068C	ART5	-	559292	Saccharomyces cerevisiae (S288c)	137	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C	PF02752	-	-	-	-	-
127922	165918	-	RNF168	hRNF168	9606	Homo sapiens	207	38	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
137127	441061	-	MARCH11	MARCH-XI	9606	Homo sapiens	1	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
34349	854102	YOL054W	PSH1	ubiquitin-protein ligase PSH1	559292	Saccharomyces cerevisiae (S288c)	363	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
111085	5048	-	PAFAH1B1	LIS1|LIS2|MDCR|MDS|PAFAH	9606	Homo sapiens	394	55	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LisH|WD40	PF08513|PF00400	-	-	-	-	-
119093	50613	-	UBQLN3	TUP-1	9606	Homo sapiens	3	5	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|ubiquitin	PF00627|PF00240	-	-	-	-	-
608671	728239	hCG_32481	MAGED4	MAGE-E1|MAGE1|MAGEE1	9606	Homo sapiens	16	40	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
106771	274	-	BIN1	AMPH2|AMPHL|SH3P9	9606	Homo sapiens	192	196	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	BAR|SH3_9	PF03114|PF14604	-	-	-	-	-
106770	273	-	AMPH	AMPH1	9606	Homo sapiens	109	30	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	BAR|SH3_9	PF03114|PF14604	-	-	-	-	-
939102	100287441	-	USP17L20	-	9606	Homo sapiens	5	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
938988	100287327	-	USP17L17	-	9606	Homo sapiens	8	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
34238	853982	YOL138C	RTC1	SEA2	559292	Saccharomyces cerevisiae (S288c)	292	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
129465	283116	-	TRIM49B	-	9606	Homo sapiens	0	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
115232	9903	-	KLHL21	-	9606	Homo sapiens	195	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
114343	8816	-	DCAF5	BCRG2|BCRP2|D14S1461E|WDR22	9606	Homo sapiens	168	98	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
34167	853908	YKR036C	CAF4	L000003417	559292	Saccharomyces cerevisiae (S288c)	199	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Caf4|WD40	PF11615|PF00400	-	-	-	-	-
109943	3741	-	KCNA5	ATFB7|HCK1|HK2|HPCN1|KV1.5|PCN1	9606	Homo sapiens	136	1	41	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
132113	386617	-	KCTD8	-	9606	Homo sapiens	8	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
132114	386618	-	KCTD4	bA321C24.3	9606	Homo sapiens	17	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
123173	80204	UG063H01	FBXO11	FBX11|PRMT9|UBR6|VIT1	9606	Homo sapiens	263	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Beta_helix|F-box-like|NosD|zf-UBR	PF13229|PF12937|PF05048|PF02207	-	-	-	-	-
127320	150726	-	FBXO41	FBX41	9606	Homo sapiens	4	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
111865	5930	My038	RBBP6	P2P-R|PACT|RBQ-1|SNAMA	9606	Homo sapiens	327	60	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DWNN|U-box|zf-CCHC_2	PF08783|PF04564|PF13696	-	-	-	-	-
111864	5929	-	RBBP5	RBQ3|SWD1	9606	Homo sapiens	616	23	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
129208	257218	RP11-545I5.1	SHPRH	bA545I5.2	9606	Homo sapiens	133	61	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Helicase_C|Linker_histone|SNF2_N	PF00271|PF00538|PF00176	-	-	-	-	-
111866	5931	RP11-716A19.5	RBBP7	RbAp46	9606	Homo sapiens	1044	39	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40	PF12265|PF00400	-	-	-	-	-
111863	5928	-	RBBP4	NURF55|RBAP48|lin-53	9606	Homo sapiens	1205	41	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40	PF12265|PF00400	-	-	-	-	-
129202	257160	-	RNF214	-	9606	Homo sapiens	125	56	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
34586	854363	YOR191W	ULS1	DIS1|RIS1|TID4|translocase ULS1|L000004381	559292	Saccharomyces cerevisiae (S288c)	281	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Helicase_C|SNF2_N	PF00271|PF00176	-	-	-	-	-
126459	136371	-	ASB10	GLC1F	9606	Homo sapiens	95	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
127926	166348	-	KBTBD12	KLHDC6	9606	Homo sapiens	6	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
119674	51676	-	ASB2	ASB-2	9606	Homo sapiens	80	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|Ank_3|SOCS_box	PF12796|PF13606|PF07525	-	-	-	-	-
119670	51667	-	NUB1	BS4|NUB1L|NYREN18	9606	Homo sapiens	102	194	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|Ubiquitin_5	PF00627|PF18037	-	-	-	-	-
131819	360023	RP11-469L3.1	ZBTB41	FRBZ1|ZNF924	9606	Homo sapiens	20	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
111464	5468	-	PPARG	CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma	9606	Homo sapiens	668	2	240	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Hormone_recep|PPARgamma_N|zf-C4	PF00104|PF12577|PF00105	-	-	-	-	-
123006	79931	-	TNIP3	ABIN-3|LIND	9606	Homo sapiens	55	1	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CC2-LZ	PF16516	-	-	-	-	-
36620	856593	YHR186C	KOG1	LAS24	559292	Saccharomyces cerevisiae (S288c)	715	8	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	HEAT|Raptor_N	PF02985|PF14538	-	-	-	-	-
127218	149478	RP11-269F19.7	BTBD19	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB	PF07707|PF00651	-	-	-	-	-
130052	285231	-	FBXW12	FBW12|FBXO12|FBXO35	9606	Homo sapiens	20	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
117057	23510	-	KCTD2	-	9606	Homo sapiens	99	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
567977	642446	-	TRIM64B	-	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-C3HC4	PF00622|PF00097	-	-	-	-	-
126850	144406	-	WDR66	CaM-IP4	9606	Homo sapiens	5	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
32692	852276	YBL007C	SLA1	cytoskeletal protein-binding protein SLA1|L000001912	559292	Saccharomyces cerevisiae (S288c)	1301	75	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SH3_1|SH3_9|SHD1	PF00018|PF14604|PF03983	-	-	-	-	-
34639	854423	YOR249C	APC5	RMC1|anaphase promoting complex subunit 5|L000004320	559292	Saccharomyces cerevisiae (S288c)	930	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC5	PF12862	-	-	-	-	-
124622	89857	-	KLHL6	-	9606	Homo sapiens	156	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120451	55148	-	UBR7	C14orf130	9606	Homo sapiens	140	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-UBR	PF02207	-	-	-	-	-
116470	11342	-	RNF13	RZF	9606	Homo sapiens	135	153	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
120105	54708	RP11-543N17.3	MARCH5	MARCH-V|MITOL|RNF153	9606	Homo sapiens	313	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
117474	25998	RP1-93K22.1	IBTK	BTBD26|BTKI	9606	Homo sapiens	176	70	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|BTB|RCC1	PF12796|PF00651|PF00415	-	-	-	-	-
35411	855273	YMR233W	TRI1	-	559292	Saccharomyces cerevisiae (S288c)	124	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	DEK_C|SWIB	PF08766|PF02201	-	-	-	-	-
32321	851858	YDR265W	PEX10	PAS4|ubiquitin-protein ligase peroxin 10|L000003961	559292	Saccharomyces cerevisiae (S288c)	247	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12|zf-RING_2	PF04757|PF13639	-	-	-	-	-
32322	851859	YDR266C	HEL2	E3 ubiquitin-protein ligase HEL2	559292	Saccharomyces cerevisiae (S288c)	158	38	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
32327	851866	YDR273W	DON1	-	559292	Saccharomyces cerevisiae (S288c)	48	1	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
120582	55295	-	KLHL26	-	9606	Homo sapiens	168	22	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120580	55293	-	UEVLD	ATTP|UEV3	9606	Homo sapiens	30	55	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Ldh_1_C|Ldh_1_N|UEV	PF02866|PF00056|PF05743	-	-	-	-	-
120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	1852	0	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
31930	851424	YDL132W	CDC53	cullin CDC53|L000000281	559292	Saccharomyces cerevisiae (S288c)	807	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Cullin|Cullin_Nedd8	PF00888|PF10557	-	-	-	-	-
120585	55298	-	RNF121	-	9606	Homo sapiens	22	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
120074	54602	-	NDFIP2	N4WBP5A	9606	Homo sapiens	89	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
120078	54620	-	FBXL19	CXXC11|Fbl19|JHDM1C	9606	Homo sapiens	133	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|PHD_4|zf-CXXC	PF00646|PF16866|PF02008	-	-	-	-	-
116877	23276	OK/SW-cl.74	KLHL18	-	9606	Homo sapiens	81	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
121212	56852	-	RAD18	RNF73	9606	Homo sapiens	707	79	0	BIOGRID	Ubiquitin binding domain protein (UBP)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SAP	PF02037	-	-	-	-	-
116656	23014	-	FBXO21	FBX21	9606	Homo sapiens	121	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Transglut_core2|YccV-like	PF13369|PF08755	-	-	-	-	-
124371	84937	-	ZNRF1	NIN283	9606	Homo sapiens	75	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
124370	84936	-	ZFYVE19	ANCHR|MPFYVE	9606	Homo sapiens	62	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FYVE	PF01363	-	-	-	-	-
116896	23304	RP3-392M17.3	UBR2	C6orf133|bA49A4.1|dJ242G1.1|dJ392M17.3	9606	Homo sapiens	226	140	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ClpS|PRT6_C|zf-UBR	PF02617|PF18995|PF02207	-	-	-	-	-
116890	23295	-	MGRN1	RNF156	9606	Homo sapiens	217	86	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
1529322	100526832	-	PHOSPHO2-KLHL23	-	9606	Homo sapiens	2	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
36269	856218	YPR103W	PRE2	DOA3|PRG1|SRR2|proteasome core particle subunit beta 5|L000001484	559292	Saccharomyces cerevisiae (S288c)	1023	9	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
128255	197370	HSPC333	NSMCE1	NSE1	9606	Homo sapiens	126	47	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SMC_Nse1|zf-RING-like	PF07574|PF08746	-	-	-	-	-
31375	850792	YLR102C	APC9	anaphase promoting complex subunit 9|L000004321	559292	Saccharomyces cerevisiae (S288c)	213	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC9	PF12856	-	-	-	-	-
124979	92799	PP203	SHKBP1	Sb1	9606	Homo sapiens	193	36	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
124970	92714	RP11-48C7.5	ARRDC1	-	9606	Homo sapiens	153	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
36869	856862	YER125W	RSP5	MDP1|MUT2|NPI1|SMM1|UBY1|NEDD4 family E3 ubiquitin-protein ligase|L000001054|L000001779|L000001220	559292	Saccharomyces cerevisiae (S288c)	1986	22	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	C2|HECT|WW	PF00168|PF00632|PF00397	-	-	-	-	-
132031	378108	-	TRIM74	TRIM50C	9606	Homo sapiens	22	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box|zf-RING_UBOX	PF00643|PF13445	-	-	-	-	-
36861	856852	YER116C	SLX8	SUMO-targeted ubiquitin ligase complex subunit SLX8	559292	Saccharomyces cerevisiae (S288c)	824	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-C3HC4	PF00097	-	-	-	-	-
124775	90864	-	SPSB3	C16orf31|SSB3	9606	Homo sapiens	70	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY	PF00622	-	-	-	-	-
124771	90850	-	ZNF598	-	9606	Homo sapiens	509	12	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
116098	10892	-	MALT1	IMD12|MLT|MLT1	9606	Homo sapiens	157	50	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ig_2|MALT1_Ig	PF13895|PF18703	-	-	-	-	-
134126	392188	-	USP17L8	USP17L10	9606	Homo sapiens	0	0	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
120859	55741	UNQ573/PRO1135	EDEM2	C20orf31|C20orf49|bA4204.1	9606	Homo sapiens	229	13	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Glyco_hydro_47	PF01532	-	-	-	-	-
116092	10885	RP4-776P7.1	WDR3	DIP2|UTP12	9606	Homo sapiens	227	30	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|Utp12|WD40	PF12894|PF04003|PF00400	-	-	-	-	-
113111	7260	-	TSSC1	-	9606	Homo sapiens	164	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
116257	11074	DAAP-112O13.2	TRIM31	C6orf13|HCG1|HCGI|RNF	9606	Homo sapiens	515	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-B_box	PF00643	-	-	-	-	-
125992	126433	-	FBXO27	FBG5|Fbx27	9606	Homo sapiens	32	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box|FBA	PF00646|PF04300	-	-	-	-	-
113118	7267	-	TTC3	DCRR1|RNF105|TPRDIII	9606	Homo sapiens	147	174	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF5861|zf-RING_2	PF19179|PF13639	-	-	-	-	-
125354	114792	RP1-39B17.1	KLHL32	BKLHD5|KIAA1900|UG0030H05|dJ21F7.1	9606	Homo sapiens	13	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
125424	115290	-	FBXO17	FBG4|FBX26|FBXO26|Fbx17	9606	Homo sapiens	108	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|FBA	PF12937|PF04300	-	-	-	-	-
113374	7542	-	ZFPL1	D11S750|MCG4	9606	Homo sapiens	523	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
113373	7541	-	ZBTB14	ZF5|ZFP-161|ZFP-5|ZFP161|ZNF478	9606	Homo sapiens	110	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
125429	115353	-	LRRC42	dJ167A19.4	9606	Homo sapiens	32	84	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_6	PF13516	-	-	-	-	-
107427	991	-	CDC20	CDC20A|bA276H19.3|p55CDC	9606	Homo sapiens	940	20	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC4_WD40|WD40	PF12894|PF00400	-	-	-	-	-
33012	852624	YGL227W	VID30	GID1|glucose-induced degradation complex subunit VID30|L000004008	559292	Saccharomyces cerevisiae (S288c)	296	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH|SPRY	PF10607|PF00622	-	-	-	-	-
120928	55819	-	RNF130	G1RZFP|GOLIATH|GP	9606	Homo sapiens	354	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
110274	4100	-	MAGEA1	CT1.1|MAGE1	9606	Homo sapiens	205	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
113751	8078	-	USP5	ISOT	9606	Homo sapiens	339	199	7	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|UCH|zf-UBP|zf-UBP_var	PF00627|PF00443|PF02148|PF17807	-	-	-	-	-
113200	7353	-	UFD1L	UFD1	9606	Homo sapiens	289	55	0	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UFD1	PF03152	-	-	-	-	-
113758	8085	-	KMT2D	AAD10|ALR|CAGL114|KABUK1|KMS|MLL2|MLL4|TNRC21	9606	Homo sapiens	289	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FYRC|FYRN|PHD|SET	PF05965|PF05964|PF00628|PF00856	-	-	-	-	-
112372	6477	-	SIAH1	SIAH1A	9606	Homo sapiens	453	5	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sina	PF03145	-	-	-	-	-
112373	6478	-	SIAH2	hSiah2	9606	Homo sapiens	217	3	3	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Sina	PF03145	-	-	-	-	-
123583	81790	-	RNF170	ADSA|SNAX1	9606	Homo sapiens	110	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF1232|zf-C3HC4	PF06803|PF00097	-	-	-	-	-
115043	9690	tcag7.998	UBE3C	HECTH2	9606	Homo sapiens	324	94	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
34917	854735	YIL075C	RPN2	SEN3|proteasome regulatory particle base subunit RPN2|L000001864	559292	Saccharomyces cerevisiae (S288c)	379	54	0	BIOGRID	Proteasome	-	-	-	-	-	-	PC_rep|RPN2_C	PF01851|PF18004	-	-	-	-	-
33789	853494	YJR036C	HUL4	putative E3 ubiquitin-protein ligase HUL4	559292	Saccharomyces cerevisiae (S288c)	74	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	HECT	PF00632	-	-	-	-	-
124057	84333	-	PCGF5	RNF159	9606	Homo sapiens	211	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RAWUL	PF16207	-	-	-	-	-
939025	100287364	-	USP17L18	-	9606	Homo sapiens	7	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	HABP4_PAI-RBP1|UCH	PF04774|PF00443	-	-	-	-	-
109940	3737	RP11-284N8.1	KCNA2	HBK5|HK4|HUKIV|KV1.2|MK2|NGK1|RBK2	9606	Homo sapiens	144	4	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
121720	57695	-	USP37	-	9606	Homo sapiens	182	77	1	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UCH|UCH_N|UIM	PF00443|PF16674|PF02809	-	-	-	-	-
115752	10489	PP7759	LRRC41	MUF1	9606	Homo sapiens	118	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	69	6	2	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ZNRF_3_ecto|zf-RING_2	PF18212|PF13639	-	-	-	-	-
123904	84132	tcag7.880	USP42	-	9606	Homo sapiens	81	13	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
109945	3743	-	KCNA7	HAK6|KV1.7	9606	Homo sapiens	0	0	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
31788	851261	YAL002W	VPS8	FUN15|VPL8|VPT8|CORVET complex membrane-binding subunit VPS8|L000003013	559292	Saccharomyces cerevisiae (S288c)	1065	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Vps8	PF12816	-	-	-	-	-
111073	5034	-	P4HB	DSI|ERBA2L|GIT|P4Hbeta|PDI|PDIA1|PHDB|PO4DB|PO4HB|PROHB	9606	Homo sapiens	602	30	1	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Thioredoxin	PF00085	-	-	-	-	-
130316	286151	-	FBXO43	EMI2|ERP1|FBX43	9606	Homo sapiens	80	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
123764	83844	RP1-97K10.1	USP26	-	9606	Homo sapiens	249	1	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH|UCH_N	PF00443|PF16674	-	-	-	-	-
119242	51043	RP11-307C12.9	ZBTB7B	CKROX|THPOK|ZBTB15|ZFP-67|ZFP67|ZNF857B|c-KROX|hcKROX	9606	Homo sapiens	85	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
122164	64412	RP3-322G13.10-004	GZF1	ZBTB23|ZNF336	9606	Homo sapiens	96	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
122162	64410	-	KLHL25	ENC-2|ENC2	9606	Homo sapiens	38	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
31651	851108	YLR392C	ART10	-	559292	Saccharomyces cerevisiae (S288c)	53	14	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
129675	283807	-	FBXL22	Fbl22	9606	Homo sapiens	22	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like	PF12937	-	-	-	-	-
126610	140456	-	ASB11	-	9606	Homo sapiens	262	0	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
115354	10043	CTA-286B10.4	TOM1	-	9606	Homo sapiens	178	98	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GAT|VHS	PF03127|PF00790	-	-	-	-	-
115352	10040	-	TOM1L1	OK/KNS-CL.3|SRCASM	9606	Homo sapiens	125	65	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GAT|VHS	PF03127|PF00790	-	-	-	-	-
34225	853969	YKR094C	RPL40B	CEP52B|UB12|UBI2|ubiquitin-ribosomal 60S subunit protein L40B fusion protein|L40e|L40B|L000002412|L000000314	559292	Saccharomyces cerevisiae (S288c)	496	12	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	Ribosomal_L40e|ubiquitin	PF01020|PF00240	-	-	-	-	-
109954	3752	RP4-773A18.7	KCND3	KCND3L|KCND3S|KSHIVB|KV4.3|SCA19|SCA22	9606	Homo sapiens	52	0	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|DUF3399|Ion_trans|Shal-type	PF02214|PF11879|PF00520|PF11601	-	-	-	-	-
34229	853973	YKR098C	UBP11	L000003171	559292	Saccharomyces cerevisiae (S288c)	80	1	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
109950	3748	-	KCNC3	KSHIIID|KV3.3|SCA13	9606	Homo sapiens	36	1	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans|Potassium_chann	PF02214|PF00520|PF11404	-	-	-	-	-
109951	3749	-	KCNC4	C1orf30|HKSHIIIC|KSHIIIC|KV3.4	9606	Homo sapiens	66	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans|Potassium_chann	PF02214|PF00520|PF11404	-	-	-	-	-
115359	10048	-	RANBP9	BPM-L|BPM90|RANBPM|RanBP7	9606	Homo sapiens	686	41	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH|LisH|SPRY	PF10607|PF08513|PF00622	-	-	-	-	-
109953	3751	-	KCND2	KV4.2|RK5	9606	Homo sapiens	48	0	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|DUF3399|Ion_trans|Shal-type	PF02214|PF11879|PF00520|PF11601	-	-	-	-	-
114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	536	38	14	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|PHD|zf-B_box	PF00439|PF00628|PF00643	-	-	-	-	-
126613	140460	-	ASB7	-	9606	Homo sapiens	119	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
115227	9898	RP11-205M9.4	UBAP2L	NICE-4	9606	Homo sapiens	453	603	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DUF3697	PF12478	-	-	-	-	-
111216	5193	-	PEX12	PAF-3|PBD3A	9606	Homo sapiens	59	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12	PF04757	-	-	-	-	-
111214	5191	RP11-55K22.6	PEX7	PBD9B|PTS2R|RCDP1|RD	9606	Homo sapiens	84	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
111215	5192	-	PEX10	NALD|PBD6A|PBD6B|RNF69	9606	Homo sapiens	49	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pex2_Pex12	PF04757	-	-	-	-	-
123169	80196	-	RNF34	CARP-1|CARP1|RFI|RIF|RIFF|hRFI	9606	Homo sapiens	102	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
115532	10238	-	DCAF7	AN11|HAN11|SWAN-1|WDR68	9606	Homo sapiens	629	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
111678	5705	-	PSMC5	S8|SUG-1|SUG1|TBP10|TRIP1|p45|p45/SUG	9606	Homo sapiens	1034	68	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
111679	5706	-	PSMC6	CADP44|HEL-S-73|P44|SUG2|p42	9606	Homo sapiens	684	49	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
115535	10241	-	CALCOCO2	NDP52	9606	Homo sapiens	744	107	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	SKICH	PF17751	-	-	-	-	-
111674	5701	-	PSMC2	MSS1|Nbla10058|S7	9606	Homo sapiens	811	67	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3	PF00004|PF17862	-	-	-	-	-
111675	5702	-	PSMC3	TBP1	9606	Homo sapiens	908	69	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
111677	5704	-	PSMC4	MIP224|RPT3|S6|TBP-7|TBP7	9606	Homo sapiens	804	41	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
114805	9410	RP11-490K7.3	SNRNP40	40K|HPRP8BP|PRP8BP|PRPF8BP|SPF38|WDR57	9606	Homo sapiens	848	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
111672	5699	-	PSMB10	LMP10|MECL1|beta2i	9606	Homo sapiens	124	11	5	BIOGRID	Proteasome	-	-	-	-	-	-	Pr_beta_C|Proteasome	PF12465|PF00227	-	-	-	-	-
111673	5700	-	PSMC1	P26S4|S4|p56	9606	Homo sapiens	768	88	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
114488	9021	-	SOCS3	ATOD4|CIS3|Cish3|SOCS-3|SSI-3|SSI3	9606	Homo sapiens	200	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2	PF00017	-	-	-	-	-
35312	855166	YMR135C	GID8	DCR1|glucose-induced degradation complex subunit GID8	559292	Saccharomyces cerevisiae (S288c)	228	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
111692	5720	-	PSME1	IFI5111|PA28A|PA28alpha|REGalpha	9606	Homo sapiens	426	40	0	BIOGRID	Proteasome	-	-	-	-	-	-	PA28_alpha|PA28_beta	PF02251|PF02252	-	-	-	-	-
111693	5721	-	PSME2	PA28B|PA28beta|REGbeta	9606	Homo sapiens	241	13	0	BIOGRID	Proteasome	-	-	-	-	-	-	PA28_alpha|PA28_beta	PF02251|PF02252	-	-	-	-	-
111690	5718	-	PSMD12	Rpn5|p55	9606	Homo sapiens	677	85	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|RPN5_C	PF01399|PF18098	-	-	-	-	-
111691	5719	-	PSMD13	HSPC027|Rpn9|S11|p40.5	9606	Homo sapiens	593	55	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI	PF01399	-	-	-	-	-
119669	51666	-	ASB4	ASB-4	9606	Homo sapiens	49	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
119668	51665	-	ASB1	ASB-1	9606	Homo sapiens	51	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
114242	8697	-	CDC23	ANAPC8|APC8|CUT23	9606	Homo sapiens	454	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ANAPC8|TPR_8	PF04049|PF13181	-	-	-	-	-
127260	150094	-	SIK1	MSK|SIK|SNF1LK	9606	Homo sapiens	99	32	3	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
119066	49854	-	ZBTB21	ZNF295	9606	Homo sapiens	206	46	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2|zf_C2H2_6	PF00651|PF00096|PF18450	-	-	-	-	-
129500	283219	-	KCTD21	KCASH2	9606	Homo sapiens	56	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
570806	645864	-	MAGEB17	-	9606	Homo sapiens	1	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
127001	146691	UNQ3124	TOM1L2	-	9606	Homo sapiens	93	146	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GAT|VHS	PF03127|PF00790	-	-	-	-	-
114791	9391	-	CIAO1	CIA1|WDR39	9606	Homo sapiens	464	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
130451	317719	-	KLHL10	SPGF11	9606	Homo sapiens	74	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
120666	55432	RP11-164O23.1	YOD1	DUBA8|OTUD2|PRO0907	9606	Homo sapiens	576	8	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
115823	10572	-	SIVA1	CD27BP|SIVA|Siva-1|Siva-2	9606	Homo sapiens	99	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Siva	PF05458	-	-	-	-	-
109046	2784	-	GNB3	-	9606	Homo sapiens	93	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
109044	2782	RP1-283E3.7	GNB1	-	9606	Homo sapiens	506	48	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
109045	2783	-	GNB2	-	9606	Homo sapiens	675	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
32511	852068	YDR457W	TOM1	E3 ubiquitin-protein ligase TOM1|L000002983	559292	Saccharomyces cerevisiae (S288c)	936	55	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	DUF908|DUF913|HECT|UBM	PF06012|PF06025|PF00632|PF14377	-	-	-	-	-
32514	852071	YDR460W	TFB3	RIG2|TFIIH/NER complex subunit TFB3|L000003496	559292	Saccharomyces cerevisiae (S288c)	119	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAT1|zf-C3HC4_5	PF06391|PF17121	-	-	-	-	-
130859	339287	-	MSL1	MSL-1|hMSL1	9606	Homo sapiens	129	29	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MSL1_dimer|PEHE	PF16801|PF15275	-	-	-	-	-
32518	852075	YDR464W	SPP41	L000002019	559292	Saccharomyces cerevisiae (S288c)	300	10	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DUF3020	PF11223	-	-	-	-	-
116402	11237	-	RNF24	G1L	9606	Homo sapiens	21	63	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
116401	11236	-	RNF139	HRCA1|RCA1|TRC8	9606	Homo sapiens	59	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TRC8_N|zf-RING_2	PF13705|PF13639	-	-	-	-	-
127710	158809	-	MAGEB6	CT3.4|MAGE-B6|MAGEB6A	9606	Homo sapiens	12	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE|MAGE_N	PF01454|PF12440	-	-	-	-	-
124165	84640	-	USP38	HP43.8KD	9606	Homo sapiens	49	28	1	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	UCH	PF00443	-	-	-	-	-
120112	54726	-	OTUD4	DUBA6|HIN1|HSHIN1	9606	Homo sapiens	769	29	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	OTU	PF02338	-	-	-	-	-
119471	51320	BM-013	MEX3C	MEX-3C|RKHD2|RNF194	9606	Homo sapiens	110	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	KH_1	PF00013	-	-	-	-	-
35426	855289	YMR247C	RKR1	LTN1|ubiquitin-protein ligase RKR1	559292	Saccharomyces cerevisiae (S288c)	339	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_2	PF13639	-	-	-	-	-
128809	222658	RP1-108K11.2	KCTD20	C6orf69|dJ108K11.3	9606	Homo sapiens	32	22	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_3	PF16017	-	-	-	-	-
131211	342931	-	RFPL4A	RFPL4|RNF210	9606	Homo sapiens	9	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|RDM|SPRY	PF13765|PF11002|PF00622	-	-	-	-	-
114465	8975	-	USP13	ISOT3|IsoT-3	9606	Homo sapiens	240	100	1	BIOGRID	Deubiquitinating enzyme (DUB)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|UCH|zf-UBP|zf-UBP_var	PF00627|PF00443|PF02148|PF17807	-	-	-	-	-
135008	401265	-	KLHL31	BKLHD6|KBTBD1|KLHL|bA345L23.2	9606	Homo sapiens	0	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
109952	3750	-	KCND1	KV4.1	9606	Homo sapiens	2	0	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|DUF3399|Ion_trans|Shal-type	PF02214|PF11879|PF00520|PF11601	-	-	-	-	-
124019	84292	-	WDR83	MORG1	9606	Homo sapiens	377	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
119988	54491	-	FAM105A	NET20	9606	Homo sapiens	419	4	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C101	PF16218	-	-	-	-	-
119989	54492	-	NEURL1B	NEURL3|hNeur2|neur2	9606	Homo sapiens	8	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Neuralized	PF07177	-	-	-	-	-
125768	122416	-	ANKRD9	-	9606	Homo sapiens	44	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121887	59345	RP11-145M9.4	GNB4	CMTD1F	9606	Homo sapiens	177	21	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
119980	54475	HUSSY-07	NLE1	Nle	9606	Homo sapiens	272	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	NLE|WD40	PF08154|PF00400	-	-	-	-	-
121227	56897	RP11-420G6.2	WRNIP1	WHIP|bA420G6.2	9606	Homo sapiens	184	93	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	AAA|AAA_assoc_2|MgsA_C|zf-WRNIP1_ubi	PF00004|PF16193|PF12002|PF18279	-	-	-	-	-
121223	56893	RP11-336K24.8	UBQLN4	A1U|A1Up|C1orf6|CIP75|UBIN	9606	Homo sapiens	325	27	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UBA|ubiquitin	PF00627|PF00240	-	-	-	-	-
116318	11146	-	GLMN	FAP|FAP48|FAP68|FKBPAP|GLML|GVM|VMGLOM	9606	Homo sapiens	302	121	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Kinetochor_Ybp2	PF08568	-	-	-	-	-
116310	11137	-	PWP1	IEF-SSP-9502	9606	Homo sapiens	222	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	725	648	12	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Peptidase_C12|UCH_C	PF01088|PF18031	-	-	-	-	-
117260	23759	-	PPIL2	CYC4|CYP60|Cyp-60|UBOX7|hCyP-60	9606	Homo sapiens	133	111	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Pro_isomerase	PF00160	-	-	-	-	-
119504	51371	HSPC014	POMP	C13orf12|PNAS-110|UMP1	9606	Homo sapiens	162	8	0	BIOGRID	Proteasome	-	-	-	-	-	-	UMP1	PF05348	-	-	-	-	-
119501	51366	-	UBR5	DD5|EDD|EDD1|HYD	9606	Homo sapiens	899	218	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	E3_UbLigase_EDD|HECT|PABP	PF11547|PF00632|PF00658	-	-	-	-	-
135642	404093	-	CUEDC1	-	9606	Homo sapiens	151	58	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	CUE	PF02845	-	-	-	-	-
120281	54941	-	RNF125	TRAC-1|TRAC1	9606	Homo sapiens	102	25	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-Di19|zf_C2HC_14	PF05605|PF18574	-	-	-	-	-
36853	856844	YER107C	GLE2	RAE1|RNA export factor GLE2|L000004084	559292	Saccharomyces cerevisiae (S288c)	473	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
124585	89122	-	TRIM4	RNF87	9606	Homo sapiens	87	37	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SPRY|zf-B_box	PF00622|PF00643	-	-	-	-	-
124582	88455	-	ANKRD13A	ANKRD13|NY-REN-25	9606	Homo sapiens	248	171	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	GPCR_chapero_1	PF11904	-	-	-	-	-
120847	55727	-	BTBD7	FUP1	9606	Homo sapiens	18	11	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB	PF07707|PF00651	-	-	-	-	-
118005	27107	-	ZBTB11	ZNF-U69274|ZNF913	9606	Homo sapiens	156	26	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|Integrase_H2C2|zf-C2H2	PF00651|PF17921|PF00096	-	-	-	-	-
120848	55728	-	N4BP2	B3BP	9606	Homo sapiens	103	166	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DUF1771|Smr	PF08590|PF01713	-	-	-	-	-
113162	7314	-	UBB	-	9606	Homo sapiens	646	291	3	BIOGRID	Ubiquitin	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
113167	7319	-	UBE2A	HHR6A|MRXS30|MRXSN|RAD6A|UBC2	9606	Homo sapiens	333	5	0	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113164	7316	-	UBC	HMG20	9606	Homo sapiens	4546	148	1	BIOGRID	Ubiquitin	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
113165	7317	CTD-2522E6.1	UBA1	A1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X	9606	Homo sapiens	656	340	9	BIOGRID	Ubiquitin activating enzyme (E1)	-	-	-	-	-	-	E1_4HB|E1_FCCH|E1_UFD|ThiF|UBA_e1_thiolCys	PF16191|PF16190|PF09358|PF00899|PF10585	-	-	-	-	-
113168	7320	-	UBE2B	E2-17kDa|HHR6B|HR6B|RAD6B|UBC2	9606	Homo sapiens	181	3	1	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
113169	7321	-	UBE2D1	E2(17)KB1|SFT|UBC4/5|UBCH5|UBCH5A	9606	Homo sapiens	940	9	1	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
122183	64446	-	DNAI2	CILD9|DIC2	9606	Homo sapiens	103	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
124340	84900	UNQ514	RNFT2	TMEM118	9606	Homo sapiens	4	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
128666	220972	RP11-67C2.1	MARCH8	MARCH-VIII|MIR|RNF178|c-MIR	9606	Homo sapiens	97	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RINGv	PF12906	-	-	-	-	-
125343	114781	RP3-322I12.1	BTBD9	dJ322I12.1	9606	Homo sapiens	86	32	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|F5_F8_type_C	PF07707|PF00651|PF00754	-	-	-	-	-
125434	115426	RP11-472F14.2	UHRF2	NIRF|RNF107|URF2	9606	Homo sapiens	214	44	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PHD|SAD_SRA|TTD|ubiquitin	PF00628|PF02182|PF12148|PF00240	-	-	-	-	-
113306	7468	RP11-262P20.3	WHSC1	MMSET|NSD2|REIIBP|TRX5|WHS	9606	Homo sapiens	380	84	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	AWS|C5HCH|HMG_box|PWWP|SET	PF17907|PF17982|PF00505|PF00855|PF00856	-	-	-	-	-
125186	112401	-	BIRC8	ILP-2|ILP2|hILP2	9606	Homo sapiens	47	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BIR	PF00653	-	-	-	-	-
107431	996	-	CDC27	ANAPC3|APC3|CDC27Hs|D0S1430E|D17S978E|H-NUC|HNUC|NUC2	9606	Homo sapiens	801	382	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TPR_1|TPR_8	PF00515|PF13181	-	-	-	-	-
107432	997	-	CDC34	E2-CDC34|UBC3|UBCH3|UBE2R1	9606	Homo sapiens	500	22	1	BIOGRID	Ubiquitin conjugating enzyme (E2)	-	-	-	-	-	-	UQ_con	PF00179	-	-	-	-	-
112364	6468	RP11-529I10.3	FBXW4	DAC|FBW4|FBWD4|SHFM3|SHSF3	9606	Homo sapiens	106	6	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box-like|WD40	PF12937|PF00400	-	-	-	-	-
120938	55833	RP11-176F3.6	UBAP2	UBAP-2	9606	Homo sapiens	199	13	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	DUF3697	PF12478	-	-	-	-	-
120937	55832	-	CAND1	TIP120|TIP120A	9606	Homo sapiens	1297	126	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	TIP120	PF08623	-	-	-	-	-
120934	55829	AD-015	VIMP	ADO15|SBBI8|SELS|SEPS1	9606	Homo sapiens	138	19	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	Selenoprotein_S	PF06936	-	-	-	-	-
120933	55827	RP4-745I14.1	DCAF6	1200006M05Rik|ARCAP|IQWD1|MSTP055|NRIP|PC326	9606	Homo sapiens	331	173	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
35098	854934	YML068W	ITT1	-	559292	Saccharomyces cerevisiae (S288c)	90	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR	PF01485	-	-	-	-	-
120930	55823	PP3476	VPS11	END1|PEP5|RNF108|hVPS11	9606	Homo sapiens	186	75	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Clathrin|VPS11_C	PF00637|PF12451	-	-	-	-	-
36039	855959	YPL144W	POC4	DMP1|PBA4	559292	Saccharomyces cerevisiae (S288c)	439	0	0	BIOGRID	Proteasome	-	-	-	-	-	-	POC3_POC4	PF10448	-	-	-	-	-
36032	855952	YPL151C	PRP46	NTC50	559292	Saccharomyces cerevisiae (S288c)	344	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
122287	64777	UNQ2508/PRO5996	RMND5B	GID2|GID2B	9606	Homo sapiens	66	17	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CLTH	PF10607	-	-	-	-	-
111683	5710	RP11-126K1.1	PSMD4	AF|AF-1|ASF|MCB1|Rpn10|S5A|pUB-R5	9606	Homo sapiens	915	71	0	BIOGRID	Proteasome|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	UIM|VWA_2	PF02809|PF13519	-	-	-	-	-
112147	6233	-	RPS27A	CEP80|HEL112|S27A|UBA80|UBC|UBCEP1|UBCEP80	9606	Homo sapiens	712	83	0	BIOGRID	Ubiquitin	-	-	-	-	-	-	Ribosomal_S27|ubiquitin	PF01599|PF00240	-	-	-	-	-
33200	852834	YGL048C	RPT6	CIM3|CRL3|SCB68|SUG1|proteasome regulatory particle base subunit RPT6|L000002174|L000000406|L000002265	559292	Saccharomyces cerevisiae (S288c)	1239	19	0	BIOGRID	Proteasome	-	-	-	-	-	-	AAA|AAA_lid_3|Prot_ATP_ID_OB	PF00004|PF17862|PF16450	-	-	-	-	-
33203	852837	YGL045W	RIM8	ART9|PAL3|YGL046W|L000004171	559292	Saccharomyces cerevisiae (S288c)	689	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Arrestin_C|Arrestin_N	PF02752|PF00339	-	-	-	-	-
123803	83892	MSTP028	KCTD10	BTBD28|ULRO61|hBACURD3	9606	Homo sapiens	283	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
123800	83889	-	WDR87	NYD-SP11	9606	Homo sapiens	22	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
123579	81786	-	TRIM7	GNIP|RNF90	9606	Homo sapiens	156	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PRY|SPRY|zf-B_box	PF13765|PF00622|PF00643	-	-	-	-	-
122573	79155	RP3-474M20.1	TNIP2	ABIN2|FLIP1|KLIP	9606	Homo sapiens	1078	15	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	EABR	PF12180	-	-	-	-	-
121711	57684	-	ZBTB26	ZNF481|bioref	9606	Homo sapiens	45	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
121714	57688	hCG_18020	ZSWIM6	AFND	9606	Homo sapiens	12	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
121716	57690	-	TNRC6C	-	9606	Homo sapiens	211	8	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Ago_hook|M_domain|TNRC6-PABC_bdg|UBA	PF10427|PF12938|PF16608|PF00627	-	-	-	-	-
121718	57692	RP4-596C3.1	MAGEE1	DAMAGE|HCA1	9606	Homo sapiens	55	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	MAGE	PF01454	-	-	-	-	-
33844	853552	YJR090C	GRR1	CAT80|COT2|SDC1|SSU2|SCF ubiquitin ligase complex subunit GRR1|L000000730	559292	Saccharomyces cerevisiae (S288c)	218	16	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	-	-	-	-	-	-	-
115036	9683	-	N4BP1	-	9606	Homo sapiens	60	39	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	RNase_Zc3h12a	PF11977	-	-	-	-	-
115037	9684	-	LRRC14	LRRC14A	9606	Homo sapiens	26	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LRR_6	PF13516	-	-	-	-	-
34364	854119	YOL038W	PRE6	proteasome core particle subunit alpha 4|L000001488	559292	Saccharomyces cerevisiae (S288c)	549	13	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
119278	51088	-	KLHL5	-	9606	Homo sapiens	27	19	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
108010	1643	-	DDB2	DDBB|UV-DDB2	9606	Homo sapiens	424	22	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WD40	PF00400	-	-	-	-	-
112981	7126	-	TNFAIP1	B12|B61|BTBD34|EDP1|hBACURD2	9606	Homo sapiens	154	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2	PF02214	-	-	-	-	-
109949	3747	-	KCNC2	KV3.2	9606	Homo sapiens	1	6	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
109948	3746	-	KCNC1	KV3.1|KV4|NGK2	9606	Homo sapiens	20	4	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
115327	10009	-	ZBTB33	ZNF-kaiso|ZNF348	9606	Homo sapiens	196	36	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
112785	6923	-	TCEB2	ELOB|SIII	9606	Homo sapiens	710	13	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	ubiquitin	PF00240	-	-	-	-	-
109942	3739	-	KCNA4	HBK4|HK1|HPCN2|HUKII|KCNA4L|KCNA8|KV1.4|PCN2	9606	Homo sapiens	115	0	4	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans|K_channel_TID	PF02214|PF00520|PF07941	-	-	-	-	-
109941	3738	RP11-284N8.3	KCNA3	HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3	9606	Homo sapiens	847	3	10	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
112786	6924	MSTP059	TCEB3	EloA|SIII|SIII p110|TCEB3A	9606	Homo sapiens	319	10	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Elongin_A|Med26	PF06881|PF08711	-	-	-	-	-
109947	3745	-	KCNB1	DRK1|EIEE26|KV2.1|h-DRK1	9606	Homo sapiens	53	5	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans|Kv2channel	PF02214|PF00520|PF03521	-	-	-	-	-
109946	3744	-	KCNA10	Kcn1|Kv1.8	9606	Homo sapiens	38	0	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
112783	6921	-	TCEB1	SIII|eloC	9606	Homo sapiens	666	49	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Skp1_POZ	PF03931	-	-	-	-	-
109944	3742	-	KCNA6	HBK2|KV1.6|PPP1R96	9606	Homo sapiens	28	0	1	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB_2|Ion_trans	PF02214|PF00520	-	-	-	-	-
31680	851140	YLR421C	RPN13	proteasome regulatory particle lid subunit RPN13	559292	Saccharomyces cerevisiae (S288c)	231	8	0	BIOGRID	Proteasome|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Proteasom_Rpn13	PF04683	-	-	-	-	-
31687	851147	YLR427W	MAG2	-	559292	Saccharomyces cerevisiae (S288c)	89	27	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	zf-RING_UBOX	PF13445	-	-	-	-	-
31138	850539	YFL009W	CDC4	SCF ubiquitin ligase complex subunit CDC4|L000000244	559292	Saccharomyces cerevisiae (S288c)	910	15	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CDC4_D|F-box-like|WD40	PF16856|PF12937|PF00400	-	-	-	-	-
115252	9924	-	PAN2	USP52	9606	Homo sapiens	422	10	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	RNase_T|UCH_1	PF00929|PF13423	-	-	-	-	-
115253	9925	RP11-397D12.5	ZBTB5	-	9606	Homo sapiens	82	8	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB	PF00651	-	-	-	-	-
126612	140459	RP11-483H20.7	ASB6	-	9606	Homo sapiens	169	9	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
115251	9923	-	ZBTB40	ZNF923	9606	Homo sapiens	33	40	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BTB|zf-C2H2	PF00651|PF00096	-	-	-	-	-
126614	140461	PP14212	ASB8	-	9606	Homo sapiens	58	1	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Ank_2|SOCS_box	PF12796|PF07525	-	-	-	-	-
115257	9929	RP3-508I15.17-002	JOSD1	dJ508I15.2	9606	Homo sapiens	71	43	0	BIOGRID	Deubiquitinating enzyme (DUB)	-	-	-	-	-	-	Josephin	PF02099	-	-	-	-	-
123158	80176	RP3-324M8.1	SPSB1	SSB-1|SSB1	9606	Homo sapiens	56	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SOCS_box|SPRY	PF07525|PF00622	-	-	-	-	-
129991	284996	-	RNF149	DNAPTP2	9606	Homo sapiens	716	34	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	PA|zf-RING_2	PF02225|PF13639	-	-	-	-	-
129222	258010	-	SVIP	-	9606	Homo sapiens	49	21	0	BIOGRID	ER-associated degradation (ERAD)	-	-	-	-	-	-	SVIP	PF15811	-	-	-	-	-
123598	81847	RP3-351K20.1	RNF146	dJ351K20.1	9606	Homo sapiens	154	33	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	WWE	PF02825	-	-	-	-	-
111669	5696	DAAP-57C1.3	PSMB8	ALDD|D6S216|D6S216E|JMP|LMP7|NKJO|PSMB5i|RING10	9606	Homo sapiens	231	9	16	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
111668	5695	RP11-101K10.7	PSMB7	Z	9606	Homo sapiens	527	15	19	BIOGRID	Proteasome	-	-	-	-	-	-	Pr_beta_C|Proteasome	PF12465|PF00227	-	-	-	-	-
111848	5913	-	RAPSN	RAPSYN|RNF205	9606	Homo sapiens	28	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Rapsyn_N|TPR_MalT|zf-RING_2	PF10579|PF17874|PF13639	-	-	-	-	-
111663	5690	RP5-983H21.1	PSMB2	HC7-I	9606	Homo sapiens	493	22	6	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
111662	5689	-	PSMB1	HC5|PMSB1|PSC5	9606	Homo sapiens	706	13	2	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
111661	5688	RP5-1005F21.4	PSMA7	C6|HSPC|RC6-1|XAPC7	9606	Homo sapiens	598	14	2	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
111660	5687	-	PSMA6	IOTA|PROS27|p27K	9606	Homo sapiens	621	75	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome|Proteasome_A_N	PF00227|PF10584	-	-	-	-	-
111667	5694	-	PSMB6	DELTA|LMPY|Y	9606	Homo sapiens	479	6	7	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
126501	138151	-	NACC2	BEND9|BTBD14|BTBD14A|BTBD31|NAC-2|RBB	9606	Homo sapiens	73	7	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BEN|BTB	PF10523|PF00651	-	-	-	-	-
111665	5692	-	PSMB4	HN3|HsN3|PROS-26|PROS26	9606	Homo sapiens	507	5	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
111664	5691	-	PSMB3	HC10-II	9606	Homo sapiens	501	10	1	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasome	PF00227	-	-	-	-	-
35308	855161	YMR131C	RRB1	-	559292	Saccharomyces cerevisiae (S288c)	171	5	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	CAF1C_H4-bd|WD40	PF12265|PF00400	-	-	-	-	-
127903	164832	-	LONRF2	RNF192	9606	Homo sapiens	41	3	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	LON_substr_bdg|zf-RING_UBOX	PF02190|PF13445	-	-	-	-	-
114492	9025	-	RNF8	hRNF8	9606	Homo sapiens	593	24	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	FHA	PF00498	-	-	-	-	-
114491	9024	HUSSY-12	BRSK2	C11orf7|PEN11B|SAD1|SADA|STK29	9606	Homo sapiens	49	65	3	BIOGRID	ER-associated degradation (ERAD)|Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	Pkinase	PF00069	-	-	-	-	-
114497	9031	-	BAZ1B	WBSCR10|WBSCR9|WSTF	9606	Homo sapiens	302	118	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Bromodomain|PHD|WAC_Acf1_DNA_bd|WHIM1|WSD	PF00439|PF00628|PF10537|PF15612|PF15613	-	-	-	-	-
126278	131377	-	KLHL40	KBTBD5|NEM8|SRYP|SYRP	9606	Homo sapiens	116	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	BACK|BTB|Kelch_1	PF07707|PF00651|PF01344	-	-	-	-	-
126279	131405	-	TRIM71	LIN-41|LIN41	9606	Homo sapiens	105	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	Filamin|NHL|zf-B_box	PF00630|PF01436|PF00643	-	-	-	-	-
111685	5713	-	PSMD7	MOV34|P40|Rpn8|S12	9606	Homo sapiens	601	19	0	BIOGRID	Proteasome	-	-	-	-	-	-	JAB|MitMem_reg	PF01398|PF13012	-	-	-	-	-
111684	5711	RP11-27I1.5	PSMD5	S5B	9606	Homo sapiens	274	33	0	BIOGRID	Proteasome	-	-	-	-	-	-	Proteasom_PSMB	PF10508	-	-	-	-	-
111687	5715	-	PSMD9	Rpn4|p27	9606	Homo sapiens	271	14	0	BIOGRID	Proteasome	-	-	-	-	-	-	Nas2_N|PDZ_6	PF18265|PF17820	-	-	-	-	-
111686	5714	-	PSMD8	HEL-S-91n|HIP6|HYPF|Nin1p|Rpn12|S14|p31	9606	Homo sapiens	372	23	0	BIOGRID	Proteasome	-	-	-	-	-	-	CSN8_PSD8_EIF3K	PF10075	-	-	-	-	-
111681	5708	-	PSMD2	P97|RPN1|S2|TRAP2	9606	Homo sapiens	871	98	0	BIOGRID	Proteasome	-	-	-	-	-	-	PC_rep|RPN1_C|RPN1_RPN2_N	PF01851|PF18051|PF17781	-	-	-	-	-
111680	5707	-	PSMD1	P112|Rpn2|S1	9606	Homo sapiens	811	145	0	BIOGRID	Proteasome	-	-	-	-	-	-	PC_rep|RPN2_C	PF01851|PF18004	-	-	-	-	-
119698	51725	-	FBXO40	FBX40	9606	Homo sapiens	22	4	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	F-box_4|zf-TRAF_2	PF15966|PF15965	-	-	-	-	-
111682	5709	-	PSMD3	P58|RPN3|S3|TSTA2	9606	Homo sapiens	1187	31	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|Rpn3_C	PF01399|PF08375	-	-	-	-	-
119697	51720	-	UIMC1	RAP80|X2HRIP110	9606	Homo sapiens	328	645	0	BIOGRID	Ubiquitin binding domain protein (UBP)	-	-	-	-	-	-	RAP80_UIM	PF18282	-	-	-	-	-
111689	5717	-	PSMD11	Rpn6|S9|p44.5	9606	Homo sapiens	649	45	0	BIOGRID	Proteasome	-	-	-	-	-	-	PCI|RPN6_C_helix|RPN6_N	PF01399|PF18503|PF18055	-	-	-	-	-
111688	5716	RP5-889N15.3	PSMD10	dJ889N15.2|p28|p28(GANK)	9606	Homo sapiens	400	18	0	BIOGRID	Proteasome	-	-	-	-	-	-	Ank|Ank_2	PF00023|PF12796	-	-	-	-	-
119053	30837	-	SOCS7	NAP4|NCKAP4	9606	Homo sapiens	71	0	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	SH2|SOCS_box	PF00017|PF07525	-	-	-	-	-
123029	79960	-	JADE1	PHF17	9606	Homo sapiens	172	43	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	EPL1	PF10513	-	-	-	-	-
34149	853887	YKR017C	HEL1	E3 ubiquitin-protein ligase HEL1	559292	Saccharomyces cerevisiae (S288c)	29	2	0	BIOGRID	Ubiquitin ligase enzyme (E3)	-	-	-	-	-	-	IBR|zf-C3HC4	PF01485|PF00097	-	-	-	-	-
