#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
15	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Viloria-Petit A (2001)	11431346	171748	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
17	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Hosokawa N (1999)	10480573	171746	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
18	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Wakita H (1999)	10601294	171747	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
19	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Suwa T (2000)	10628369	171745	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
20	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Burke P (2001)	11408594	141935	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
40	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Duvic M (2008)	18684057	171751	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
41	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Turturro F (2007)	17187516	171750	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
42	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
43	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Overington JP (2006)	17139284	171741	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
44	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Murphy JR (1988)	3124610	171755	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
45	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Kiyokawa T (1989)	2786749	171754	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
46	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	binder	target	Imming P (2006)	17016423	171742	4	Denileukin diftitox	Diphtheria toxin precursor|DT|NAD(+--diphthamide ADP- ribosyltransferase)	ontak	DRUGBANK	DB00004	C2560H4042N678O799S17	biologic	L01XX29	173146-27-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
62	112987	7133	-	TNFRSF1B	CD120b|TBPII|TNF-R-II|TNF-R75|TNFBR|TNFR1B|TNFR2|TNFR80|p75|p75TNFR	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
78	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Chen X (2002)	11752352	171740	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
79	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Park YC (1999)	10206649	144893	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
80	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Moreland LW (1999)	10375846	171766	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
81	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Grell M (1999)	10357816	171767	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
82	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Calabrese LH (1999)	10405518	171768	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
83	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Sandborn WJ (1999)	10338381	171769	5	Etanercept	p75|CD120b|Tumor necrosis factor receptor 2|TNF-R2|Tumor necrosis factor receptor type II|Tumor necrosis factor receptor superfamily member 1B precursor|p80 TNF-alpha receptor	enbrel|brenzys	DRUGBANK	DB00005	C2224H3475N621O698S36	biologic	L04AB01	185243-69-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
112	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hilleman DE (2007)	17963464	171789	9	Alteplase	t-plasminogen activator|t-PA|tPA|Tissue-type plasminogen activator precursor	activase rt-pa|lysatec rt - pa	DRUGBANK	DB00009	C2569H3928N746O781S40	biologic	B01AD02|S01XA13	105857-23-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
113	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	9	Alteplase	t-plasminogen activator|t-PA|tPA|Tissue-type plasminogen activator precursor	activase rt-pa|lysatec rt - pa	DRUGBANK	DB00009	C2569H3928N746O781S40	biologic	B01AD02|S01XA13	105857-23-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
114	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	9	Alteplase	t-plasminogen activator|t-PA|tPA|Tissue-type plasminogen activator precursor	activase rt-pa|lysatec rt - pa	DRUGBANK	DB00009	C2569H3928N746O781S40	biologic	B01AD02|S01XA13	105857-23-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
132	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Gerstein ES (2003)	12785198	171800	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
133	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hellgren M (2003)	12709915	171797	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
134	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Chang H (2003)	12745435	171796	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
135	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Gamberi G (2003)	12579271	171799	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
136	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Shetty S (2003)	12642587	171798	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
148	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Wygrecka M (2004)	15351849	171809	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
149	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Grebenchtchikov N (2005)	15944795	171808	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
150	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Swartz JM (2004)	15277569	171810	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
151	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Iglesias D (2005)	15640330	171811	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
152	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Fernandez-Soria V (2006)	16327990	171812	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
153	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Stief TW (2003)	14507109	171813	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
154	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Chang H (2003)	12745435	171796	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
155	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Lindholt JS (2003)	12787697	171816	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
156	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Wells RG (2003)	12893898	171814	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
157	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Aleman C (2003)	12826021	171815	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
158	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Bell WR (2003)	12556741	171818	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
159	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Chang H (2003)	12745435	171796	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
160	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Gamberi G (2003)	12579271	171799	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
161	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Zhang G (2003)	12707394	171817	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
162	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Wielockx B (2003)	12824001	171819	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
163	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Fuchs T (2003)	12817472	171823	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
164	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Gutova M (2007)	17327908	171822	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
165	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Czekay RP (2003)	12615913	171821	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
166	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Kanse SM (2004)	14679304	171820	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
167	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Beaufort N (2004)	14688365	171825	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
168	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Guerrero J (2004)	14720519	171824	13	Urokinase	uPA|Urokinase-type plasminogen activator precursor|U-plasminogen activator	kinlytic (urokinase for inject	DRUGBANK	DB00013	C1376H2145N383O406S18	biologic	B01AD04	9039-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
186	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hilleman DE (2007)	17963464	171789	15	Reteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	retavase	DRUGBANK	DB00015	C1736H2671N499O522S22	biologic	B01AD07	133652-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
187	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	15	Reteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	retavase	DRUGBANK	DB00015	C1736H2671N499O522S22	biologic	B01AD07	133652-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
188	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	15	Reteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	retavase	DRUGBANK	DB00015	C1736H2671N499O522S22	biologic	B01AD07	133652-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
278	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	chaperone	target	Imming P (2006)	17016423	171742	25	Antihemophilic Factor (Recombinant)	rAHF|Factor VIII (Recombinant)|Antihemophilic factor (human)|Antihemophilic factor human|Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method|moroctocog alfa|Antihemophilic Factor, Human Recombinant|Human Factor VIII (Recombinant)|octocog alfa	kogenate fs|kryobulin vh 500 u	DRUGBANK	DB00025	C11794H18314N3220O3553S83	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
279	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	chaperone	target	Kaufman RJ (1997)	9607108	171871	25	Antihemophilic Factor (Recombinant)	rAHF|Factor VIII (Recombinant)|Antihemophilic factor (human)|Antihemophilic factor human|Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method|moroctocog alfa|Antihemophilic Factor, Human Recombinant|Human Factor VIII (Recombinant)|octocog alfa	kogenate fs|kryobulin vh 500 u	DRUGBANK	DB00025	C11794H18314N3220O3553S83	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
280	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	chaperone	target	Pipe SW (1998)	9525969	1039	25	Antihemophilic Factor (Recombinant)	rAHF|Factor VIII (Recombinant)|Antihemophilic factor (human)|Antihemophilic factor human|Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method|moroctocog alfa|Antihemophilic Factor, Human Recombinant|Human Factor VIII (Recombinant)|octocog alfa	kogenate fs|kryobulin vh 500 u	DRUGBANK	DB00025	C11794H18314N3220O3553S83	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
281	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	chaperone	target	Overington JP (2006)	17139284	171741	25	Antihemophilic Factor (Recombinant)	rAHF|Factor VIII (Recombinant)|Antihemophilic factor (human)|Antihemophilic factor human|Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method|moroctocog alfa|Antihemophilic Factor, Human Recombinant|Human Factor VIII (Recombinant)|octocog alfa	kogenate fs|kryobulin vh 500 u	DRUGBANK	DB00025	C11794H18314N3220O3553S83	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
282	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	chaperone	target	Srour MA (2008)	17899080	171873	25	Antihemophilic Factor (Recombinant)	rAHF|Factor VIII (Recombinant)|Antihemophilic factor (human)|Antihemophilic factor human|Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method|moroctocog alfa|Antihemophilic Factor, Human Recombinant|Human Factor VIII (Recombinant)|octocog alfa	kogenate fs|kryobulin vh 500 u	DRUGBANK	DB00025	C11794H18314N3220O3553S83	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
299	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Do H (2006)	17083033	171889	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
300	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Vannier E (1999)	10210771	171888	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
301	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
302	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Vamvakopoulos J (2002)	12355453	171885	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
303	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Dayer JM (2003)	12817089	171884	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
304	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	So A (2007)	17352828	171887	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
305	109770	3554	-	IL1R1	CD121A|D2S1473|IL-1R-alpha|IL1R|IL1RA|P80	9606	Homo sapiens	antagonist	target	Tang YH (2007)	17498496	171886	26	Anakinra	IL1 inhibitor|ICIL-1RA|IL-1RN|IRAP|Interleukin-1 receptor antagonist protein precursor|IL-1ra	kineret	DRUGBANK	DB00026	C759H1186N208O232S10	biologic	L04AC03	143090-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
345	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hilleman DE (2007)	17963464	171789	29	Anistreplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	eminase 30 units	DRUGBANK	DB00029	C2569H3928N746O781S40	biologic	B01AD03	81669-57-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
346	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	29	Anistreplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	eminase 30 units	DRUGBANK	DB00029	C2569H3928N746O781S40	biologic	B01AD03	81669-57-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
347	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	29	Anistreplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	eminase 30 units	DRUGBANK	DB00029	C2569H3928N746O781S40	biologic	B01AD03	81669-57-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
358	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
359	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
362	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
363	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
376	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Lindberg P (2001)	11163592	171900	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
377	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hattori M (2001)	14564902	171899	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
378	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Hilleman DE (2007)	17963464	171789	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
383	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	unknown	target	Allen S (1997)	9359841	1042	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
384	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Ferrier CM (2002)	12210068	171901	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
385	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Maupas-Schwalm F (2004)	15231724	171902	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
386	111345	5329	-	PLAUR	CD87|U-PAR|UPAR|URKR	9606	Homo sapiens	unknown	target	Bankl HC (2001)	11447759	171903	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
388	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Verkleij-Hagoort AC (2007)	17141398	171904	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
389	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Bremer HA (1994)	7958159	171905	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
390	111092	5055	-	SERPINB2	HsT1201|PAI|PAI-2|PAI2|PLANH2	9606	Homo sapiens	unknown	target	Stump DC (1986)	3091604	171906	31	Tenecteplase	t-plasminogen activator|tPA|Tissue-type plasminogen activator precursor|t- PA	tnkase	DRUGBANK	DB00031	C2561H3919N747O781S40	biologic	B01AD11	191588-94-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
525	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Ouyang Y (1999)	10207608	171999	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
526	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Waldmann TA (2007)	17530023	171998	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
527	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Vlad G (2007)	17584597	171997	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
528	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Waldmann TA (2007)	17216565	171996	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
529	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Liu BY (2006)	16864089	171995	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
530	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Recchia F (2003)	16767920	171994	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
531	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	modulator	target	Chen X (2002)	11752352	171740	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
532	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Ouyang Y (1999)	10207608	171999	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
533	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Waldmann TA (2007)	17530023	171998	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
534	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Vlad G (2007)	17584597	171997	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
535	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Waldmann TA (2007)	17216565	171996	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
536	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Liu BY (2006)	16864089	171995	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
537	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Recchia F (2003)	16767920	171994	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
538	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	40	Aldesleukin	Recombinant interleukin-2 human|Interleukin-2(2-133),125-ser|125-L-serine-2-133-interleukin 2 (human reduced)|Interleukin-2 aldesleukin	proleukin	DRUGBANK	DB00041	C690H1115N177O202S6	biologic	L03AC01	110942-02-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
561	112952	7097	-	TLR2	CD282|TIL4	9606	Homo sapiens	unknown	target	Welty DM (2003)	14617145	172016	44	OspA lipoprotein	Outer surface protein A precursor	-	DRUGBANK	DB00045	C1198H2012N322O422S2	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
615	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Chen X (2002)	11752352	171740	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
616	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Flendrie M (2003)	14532145	172043	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
617	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Lorenz HM (2002)	12044041	172044	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
618	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Bang LM (2004)	15046527	172045	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
619	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Klinkhoff A (2004)	15200343	172046	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
620	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Aguillon JC (2003)	15022409	172042	50	Adalimumab	Ig gamma-1 chain C region	humira	DRUGBANK	DB00051	C6428H9912N1694O1987S46	biologic	L04AB04	331731-18-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
672	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Cerchiara E (2007)	17566522	172067	54	Drotrecogin alfa	Drotrecogin alfa activated|Blood coagulation factor XIV (human)|Drotrecogin-alfa|Recombinant human activated protein C (rH-APC)|Activated protein C|Drotrecogin alfa (activated)|Drotrecogin alfa, activated|Drotrecogin alfa (activated), lyophilized	xigris (5mg/vial)|xigris  (20m	DRUGBANK	DB00055	C1786H2779N509O519S29	biologic	B01AD10	98530-76-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
673	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Dhainaut JF (2003)	14515185	172070	54	Drotrecogin alfa	Drotrecogin alfa activated|Blood coagulation factor XIV (human)|Drotrecogin-alfa|Recombinant human activated protein C (rH-APC)|Activated protein C|Drotrecogin alfa (activated)|Drotrecogin alfa, activated|Drotrecogin alfa (activated), lyophilized	xigris (5mg/vial)|xigris  (20m	DRUGBANK	DB00055	C1786H2779N509O519S29	biologic	B01AD10	98530-76-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
674	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Carr ME (2001)	11259926	172068	54	Drotrecogin alfa	Drotrecogin alfa activated|Blood coagulation factor XIV (human)|Drotrecogin-alfa|Recombinant human activated protein C (rH-APC)|Activated protein C|Drotrecogin alfa (activated)|Drotrecogin alfa, activated|Drotrecogin alfa (activated), lyophilized	xigris (5mg/vial)|xigris  (20m	DRUGBANK	DB00055	C1786H2779N509O519S29	biologic	B01AD10	98530-76-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
675	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	unknown	target	Idell S (2002)	12004248	172069	54	Drotrecogin alfa	Drotrecogin alfa activated|Blood coagulation factor XIV (human)|Drotrecogin-alfa|Recombinant human activated protein C (rH-APC)|Activated protein C|Drotrecogin alfa (activated)|Drotrecogin alfa, activated|Drotrecogin alfa (activated), lyophilized	xigris (5mg/vial)|xigris  (20m	DRUGBANK	DB00055	C1786H2779N509O519S29	biologic	B01AD10	98530-76-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
768	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Mori S (2006)	16622728	172132	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
769	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Danese S (2006)	16456024	172133	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
770	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Magro F (2005)	15674127	172134	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
771	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Popa C (2005)	15804598	172135	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
772	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Shen C (2005)	15691299	172136	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
773	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Mimura T (2007)	17642244	172137	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
774	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Maini RN (2002)	12110154	172138	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
775	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Braun J (2005)	16052578	172139	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
776	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
777	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Sapienza MS (2004)	15481318	172141	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
778	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Tobin AM (2005)	15691217	172140	64	Infliximab	Ig gamma-1 chain C region	remicade|remsima|inflectra	DRUGBANK	DB00065	C6428H9912N1694O1987S46	biologic	L04AB02	170277-31-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
812	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1998)	9850732	172163	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
813	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (2001)	11327694	172166	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
814	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Locci P (1995)	7648625	172165	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
815	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1997)	9435505	172164	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
829	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Radulescu RT (2007)	17475416	172174	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
830	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Degeorges A (1999)	10383131	172175	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
831	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Lopez-Bermejo A (2000)	11089538	172176	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
832	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
833	109711	3490	-	IGFBP7	AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
839	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
840	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
841	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Biener Y (1990)	1701386	172180	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
893	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	71	Trastuzumab	Anti HER2|Ig gamma-1 chain C region	herceptin|perjeta-herceptin	DRUGBANK	DB00072	C6470H10012N1726O2013S42	biologic	L01XC03	180288-69-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
968	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Garcia CD (2006)	16908318	172228	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
969	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Choy BY (2003)	12591363	172229	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
970	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Chen X (2002)	11752352	171740	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
971	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Kovarik J (1998)	9695721	172226	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
972	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Berard JL (1999)	10512062	172227	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
973	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Mentre F (1999)	10567956	172230	73	Basiliximab	chimeric mouse-human antiCD25|Ig gamma-1 chain C region	simulect	DRUGBANK	DB00074	C6378H9844N1698O1997S48	biologic	L04AC02	179045-86-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1294	109610	3383	-	ICAM1	BB2|CD54|P3.58	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	103	Natalizumab	Anti-alpha4 integrin|Anti-VLA4	tysabri	DRUGBANK	DB00108	-	biologic	L04AA23	189261-10-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1362	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Garcia CD (2006)	16908318	172228	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1363	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Przepiorka D (2000)	10607689	172453	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1364	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Chen X (2002)	11752352	171740	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1365	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Monti P (2009)	19788505	172457	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1366	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Patlolla V (2007)	17564638	172456	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1367	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Krouwels FH (1996)	8600944	172455	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1368	109774	3559	RP11-536K7.1	IL2RA	CD25|IDDM10|IL2R|TCGFR|p55	9606	Homo sapiens	antibody	target	Shamsi TS (2005)	16304857	172454	106	Daclizumab	Dacliximab|Daclizumab beta	zenapax 5mg/ml|zinbryta	DRUGBANK	DB00111	C6332H9808N1678O1989S42	biologic	L04AC01	152923-56-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1387	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1388	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gerber HP (2005)	15705858	172458	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
2128	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Mayes MA (2007)	17167165	173052	125	Adenosine monophosphate	Adenosine 5'-(dihydrogen phosphate)|5'-Adenosine monophosphate|Adenosine 5'-monophosphate|Adenosine-5'-monophosphoric acid|PAdo|Adenylate|Phosphate d'adenosine|Adenosine-5'-Monophosphate|5'-O-Phosphonoadenosine|Adenosine phosphate|Ado5'p|Adenosine-5'p|AMP|Fosfato de adenosina|5'-Adenylic acid|ADENOSINE monophosphate|Phosaden|Adenylic acid|Phosphaden|5'-AMP|Adenosini phosphas|Adenosine 5'-phosphate	-	DRUGBANK	DB00131	C10H14N5O7P	small molecule	-	61-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UDMBCSSLTHHNCD-KQYNXXCUSA-N
2945	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Das UN (2005)	15990700	173594	148	Dihomo-gamma-linolenic acid	(Z,Z,Z)-8,11,14-Eicosatrienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoate|all-cis-Eicosa-8,11,14-triensaeure|Homo-gamma-linolenic acid|all-cis-icosa-8,11,14-trienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoic acid|Homo-gamma-linolensaeure|gamma-Homolinolenic acid|Dihomo--linolenic acid|DGLA|20:3, n-6,9,12 all-cis|8,11,14-Eicosatrienoic Acid|all-cis-8,11,14-eicosatrienoic acid|eicosa-8Z,11Z,14Z-trienoic acid|C20:3, n-6,9,12 all-cis|cis,cis,cis-8,11,14-eicosatrienoic acid|(8Z,11Z,14Z)-Icosatrienoic acid|all-cis-eicosa-8,11,14-trienoic acid|8c,11c,14c-Eicosatriensaeure|8c,11c,14c-eicosatrienoic acid|all-cis-8,11,14-icosatrienoic acid	-	DRUGBANK	DB00154	C20H34O2	small molecule	-	1783-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOBAELRKJCKHQD-QNEBEIHSSA-N
2946	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Das UN (2005)	16190133	173591	148	Dihomo-gamma-linolenic acid	(Z,Z,Z)-8,11,14-Eicosatrienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoate|all-cis-Eicosa-8,11,14-triensaeure|Homo-gamma-linolenic acid|all-cis-icosa-8,11,14-trienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoic acid|Homo-gamma-linolensaeure|gamma-Homolinolenic acid|Dihomo--linolenic acid|DGLA|20:3, n-6,9,12 all-cis|8,11,14-Eicosatrienoic Acid|all-cis-8,11,14-eicosatrienoic acid|eicosa-8Z,11Z,14Z-trienoic acid|C20:3, n-6,9,12 all-cis|cis,cis,cis-8,11,14-eicosatrienoic acid|(8Z,11Z,14Z)-Icosatrienoic acid|all-cis-eicosa-8,11,14-trienoic acid|8c,11c,14c-Eicosatriensaeure|8c,11c,14c-eicosatrienoic acid|all-cis-8,11,14-icosatrienoic acid	-	DRUGBANK	DB00154	C20H34O2	small molecule	-	1783-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOBAELRKJCKHQD-QNEBEIHSSA-N
2947	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Thuresson ED (2001)	11121413	173590	148	Dihomo-gamma-linolenic acid	(Z,Z,Z)-8,11,14-Eicosatrienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoate|all-cis-Eicosa-8,11,14-triensaeure|Homo-gamma-linolenic acid|all-cis-icosa-8,11,14-trienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoic acid|Homo-gamma-linolensaeure|gamma-Homolinolenic acid|Dihomo--linolenic acid|DGLA|20:3, n-6,9,12 all-cis|8,11,14-Eicosatrienoic Acid|all-cis-8,11,14-eicosatrienoic acid|eicosa-8Z,11Z,14Z-trienoic acid|C20:3, n-6,9,12 all-cis|cis,cis,cis-8,11,14-eicosatrienoic acid|(8Z,11Z,14Z)-Icosatrienoic acid|all-cis-eicosa-8,11,14-trienoic acid|8c,11c,14c-Eicosatriensaeure|8c,11c,14c-eicosatrienoic acid|all-cis-8,11,14-icosatrienoic acid	-	DRUGBANK	DB00154	C20H34O2	small molecule	-	1783-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOBAELRKJCKHQD-QNEBEIHSSA-N
2948	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Levin G (2002)	11939906	173592	148	Dihomo-gamma-linolenic acid	(Z,Z,Z)-8,11,14-Eicosatrienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoate|all-cis-Eicosa-8,11,14-triensaeure|Homo-gamma-linolenic acid|all-cis-icosa-8,11,14-trienoic acid|(Z,Z,Z)-8,11,14-Icosatrienoic acid|Homo-gamma-linolensaeure|gamma-Homolinolenic acid|Dihomo--linolenic acid|DGLA|20:3, n-6,9,12 all-cis|8,11,14-Eicosatrienoic Acid|all-cis-8,11,14-eicosatrienoic acid|eicosa-8Z,11Z,14Z-trienoic acid|C20:3, n-6,9,12 all-cis|cis,cis,cis-8,11,14-eicosatrienoic acid|(8Z,11Z,14Z)-Icosatrienoic acid|all-cis-eicosa-8,11,14-trienoic acid|8c,11c,14c-Eicosatriensaeure|8c,11c,14c-eicosatrienoic acid|all-cis-8,11,14-icosatrienoic acid	-	DRUGBANK	DB00154	C20H34O2	small molecule	-	1783-84-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOBAELRKJCKHQD-QNEBEIHSSA-N
3453	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Machida T (2005)	16141635	173820	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3454	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Lee JY (2003)	12562875	173822	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3455	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chene G (2007)	17459764	173843	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3456	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Vecchio AJ (2010)	20463020	173819	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3457	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Das UN (2005)	16190133	173591	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3458	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ait-Said F (2003)	12573452	173842	153	Icosapent	all-cis-5,8,11,14,17-eicosapentaenoic acid|(all-Z)-5,8,11,14,17-Eicosapentaenoic acid|cis-5,8,11,14,17-Eicosapentaenoic acid|Icosapent|EPA|Timnodonic acid|Eicosapentaenoic acid|5,8,11,14,17-Icosapentaenoic acid|Icosapentum|(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid|cis, cis, cis, cis, cis-Eicosa-5,8,11,14,17-pentaenoic acid|5,8,11,14,17-EICOSAPENTAENOIC acid|all-cis-5,8,11,14,17-icosapentaenoic acid|all-cis-icosa-5,8,11,14,17-pentaenoic acid|Icosapentaenoic acid|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate|(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid|Icosapento|cis-delta(5,8,11,14,17)-Eicosapentaenoic acid|cis-5,8,11,14,17-EPA	natelle one|gesticare dha|ulti	DRUGBANK	DB00159	C20H30O2	small molecule	-	10417-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JAZBEHYOTPTENJ-JLNKQSITSA-N
3749	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3750	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
4137	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	antagonist	target	Kruszynska YT (2000)	10871202	174275	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4138	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	antagonist	target	Nordt TK (2000)	10770198	174277	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4139	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	antagonist	target	Kato K (2000)	10831180	174276	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4140	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	antagonist	target	Gottschling-Zeller H (2000)	10768100	174279	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4141	111091	5054	-	SERPINE1	PAI|PAI-1|PAI1|PLANH1	9606	Homo sapiens	antagonist	target	Sobel BE (1999)	10418858	174278	190	Troglitazone	-	-	DRUGBANK	DB00197	C24H27NO5S	small molecule	A10BG01	97322-87-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GXPHKUHSUJUWKP-UHFFFAOYSA-N
4261	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Blasina A (1999)	10531013	174349	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4262	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Sarkaria JN (1999)	10485486	174348	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4568	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Cipolla G (2002)	12208114	174550	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4569	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Generini S (2002)	12463455	174551	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4570	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Mifflin RC (2004)	14742690	174552	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4571	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Pruzanski W (1997)	9256165	174553	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4572	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Distrutti E (2006)	16855178	174554	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4704	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4705	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Bantel H (2000)	11151876	174545	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4706	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4707	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Cipolla G (2002)	12208114	174550	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4708	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Generini S (2002)	12463455	174551	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4709	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Mifflin RC (2004)	14742690	174552	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4710	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Pruzanski W (1997)	9256165	174553	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4711	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Distrutti E (2006)	16855178	174554	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
5089	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Sakaguchi M (2006)	16551906	174881	274	Lidocaine	2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide|alpha-diethylamino-2,6-dimethylacetanilide|Lignocaine|2-(Diethylamino)-2',6'-acetoxylidide|-diethylamino-2,6-dimethylacetanilide	scar zone burn gel|sting relie	DRUGBANK	DB00281	C14H22N2O	small molecule	C05AD01|N01BB52|D04AB01|C01BB01|N01BB02|R02AD02|S01HA07|S02DA01	137-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNJVILVZKWQKPM-UHFFFAOYSA-N
5477	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Lee YS (2007)	17175104	175138	309	Acetaminophen	actaminophne|p-hydroxyacetanilide|p-acetamidophenol|p-hydroxy-acetanilid|p-acetaminophenol|Acenol|N-acetyl-p-aminophenol|4-(Acetylamino)phenol|Paracetamolum|4'-hydroxyacetanilide|Paractamol|p-Acetylaminophenol|Acetaminophen|p-hydroxyphenolacetamide|Paracetamol|4-acetamidophenol|APAP|acetaminofn	tylenol cold and flu nighttime	DRUGBANK	DB00316	C8H9NO2	small molecule	N02BE71|N02BE01|N02BE51	103-90-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZVAJINKPMORJF-UHFFFAOYSA-N
5478	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	309	Acetaminophen	actaminophne|p-hydroxyacetanilide|p-acetamidophenol|p-hydroxy-acetanilid|p-acetaminophenol|Acenol|N-acetyl-p-aminophenol|4-(Acetylamino)phenol|Paracetamolum|4'-hydroxyacetanilide|Paractamol|p-Acetylaminophenol|Acetaminophen|p-hydroxyphenolacetamide|Paracetamol|4-acetamidophenol|APAP|acetaminofn	tylenol cold and flu nighttime	DRUGBANK	DB00316	C8H9NO2	small molecule	N02BE71|N02BE01|N02BE51	103-90-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZVAJINKPMORJF-UHFFFAOYSA-N
5479	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Weinheimer EM (2007)	17322116	175137	309	Acetaminophen	actaminophne|p-hydroxyacetanilide|p-acetamidophenol|p-hydroxy-acetanilid|p-acetaminophenol|Acenol|N-acetyl-p-aminophenol|4-(Acetylamino)phenol|Paracetamolum|4'-hydroxyacetanilide|Paractamol|p-Acetylaminophenol|Acetaminophen|p-hydroxyphenolacetamide|Paracetamol|4-acetamidophenol|APAP|acetaminofn	tylenol cold and flu nighttime	DRUGBANK	DB00316	C8H9NO2	small molecule	N02BE71|N02BE01|N02BE51	103-90-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZVAJINKPMORJF-UHFFFAOYSA-N
5480	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hinz B (2008)	17884974	175136	309	Acetaminophen	actaminophne|p-hydroxyacetanilide|p-acetamidophenol|p-hydroxy-acetanilid|p-acetaminophenol|Acenol|N-acetyl-p-aminophenol|4-(Acetylamino)phenol|Paracetamolum|4'-hydroxyacetanilide|Paractamol|p-Acetylaminophenol|Acetaminophen|p-hydroxyphenolacetamide|Paracetamol|4-acetamidophenol|APAP|acetaminofn	tylenol cold and flu nighttime	DRUGBANK	DB00316	C8H9NO2	small molecule	N02BE71|N02BE01|N02BE51	103-90-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZVAJINKPMORJF-UHFFFAOYSA-N
5481	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Nicholson RI (2001)	11566608	175152	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5482	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Albanell J (2001)	11522647	175151	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5483	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Arteaga CL (2001)	11673690	175150	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5484	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5485	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Ciardiello F (2000)	10815932	175148	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5486	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Moasser MM (2001)	11585753	175149	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5614	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Pilane CM (2005)	15668944	175250	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5615	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Jerde TJ (2005)	15667901	175249	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5616	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yokota A (2005)	15831440	175248	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5617	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Armstrong PJ (2005)	15770365	175247	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5618	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Zhang GS (2004)	15730717	175251	321	Indomethacin	Indomethacin|Indometacinum|1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid|Indocin|{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid|Aconip|Indometacin|Indometacine|Indometacina	indocid cap 25mg|tivorbex|apo 	DRUGBANK	DB00328	C19H16ClNO4	small molecule	M01AB51|S01BC01|M02AA23|S01CC02|M01AB01|C01EB03	53-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGIGDMFJXJATDK-UHFFFAOYSA-N
5759	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	potentiator	target	Reitamo S (2002)	12113647	175334	329	Pimecrolimus	Pimecrolimusum|Pimecrolimus|33-Epi-chloro-33-desoxyascomycin	elidel	DRUGBANK	DB00337	C43H68ClNO11	small molecule	D11AH02	137071-32-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KASDHRXLYQOAKZ-XDSKOBMDSA-N
6016	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	agonist	target	Szabo S (1995)	8578198	175527	356	Sucralfate	Sucralfate|Sucralfatum|Sucralfato|Hexadeca--hydroxytetracosahydroxy[8-[1,3,4,6-tetra-O-sulfo--Dfructofuranosyl--D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum|Sucralfat	sulcrate suspension plus|caraf	DRUGBANK	DB00364	C11H28Al8O51S8	small molecule	A02BX02	54182-58-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNQYNQBOVCBZIQ-JQOFMKNESA-A
6017	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	agonist	target	Konturek SJ (1990)	1970337	175531	356	Sucralfate	Sucralfate|Sucralfatum|Sucralfato|Hexadeca--hydroxytetracosahydroxy[8-[1,3,4,6-tetra-O-sulfo--Dfructofuranosyl--D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum|Sucralfat	sulcrate suspension plus|caraf	DRUGBANK	DB00364	C11H28Al8O51S8	small molecule	A02BX02	54182-58-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNQYNQBOVCBZIQ-JQOFMKNESA-A
6018	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	agonist	target	Tarnawski A (1995)	8578218	175530	356	Sucralfate	Sucralfate|Sucralfatum|Sucralfato|Hexadeca--hydroxytetracosahydroxy[8-[1,3,4,6-tetra-O-sulfo--Dfructofuranosyl--D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum|Sucralfat	sulcrate suspension plus|caraf	DRUGBANK	DB00364	C11H28Al8O51S8	small molecule	A02BX02	54182-58-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNQYNQBOVCBZIQ-JQOFMKNESA-A
6019	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	agonist	target	Szabo S (1991)	1957124	175528	356	Sucralfate	Sucralfate|Sucralfatum|Sucralfato|Hexadeca--hydroxytetracosahydroxy[8-[1,3,4,6-tetra-O-sulfo--Dfructofuranosyl--D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum|Sucralfat	sulcrate suspension plus|caraf	DRUGBANK	DB00364	C11H28Al8O51S8	small molecule	A02BX02	54182-58-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNQYNQBOVCBZIQ-JQOFMKNESA-A
6020	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	agonist	target	Korman MG (1994)	7948825	175529	356	Sucralfate	Sucralfate|Sucralfatum|Sucralfato|Hexadeca--hydroxytetracosahydroxy[8-[1,3,4,6-tetra-O-sulfo--Dfructofuranosyl--D-glucopyranoside tetrakis(hydrogen sulfato)8-)]]hexadecaaluminum|Sucralfat	sulcrate suspension plus|caraf	DRUGBANK	DB00364	C11H28Al8O51S8	small molecule	A02BX02	54182-58-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNQYNQBOVCBZIQ-JQOFMKNESA-A
7154	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7155	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Elliott SN (1995)	7615202	176244	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7156	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Roy HK (2001)	11304699	176245	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7157	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hedner T (2004)	15456329	176242	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7158	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	van Kraaij DJ (2002)	12047490	176243	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7159	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Fackovcova D (2001)	11153163	176241	453	Nabumetone	Nabumtone|4-(6-Methoxy-2-naphthalenyl)-2-butanone|Nabumetona|4-(6-Methoxy-2-naphthyl)-2-butanone|Nabumeton|Nabumetonum|Relafen|Nabumetone	apo-nabumetone|relafen tablets	DRUGBANK	DB00461	C15H16O2	small molecule	M01AX01	42924-53-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BLXXJMDCKKHMKV-UHFFFAOYSA-N
7205	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Blais V (2002)	12446609	176260	457	Ketorolac	Ketorolacum|Ketorolaco|Ktorolac|(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid|rac-Ketorolac|(+-)-Ketorolac|Ketorolac	toradol|acular ls|toradol tab 	DRUGBANK	DB00465	C15H13NO3	small molecule	M01AB15|S01BC05	74103-06-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OZWKMVRBQXNZKK-UHFFFAOYSA-N
7206	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ma W (2003)	14568028	176261	457	Ketorolac	Ketorolacum|Ketorolaco|Ktorolac|(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid|rac-Ketorolac|(+-)-Ketorolac|Ketorolac	toradol|acular ls|toradol tab 	DRUGBANK	DB00465	C15H13NO3	small molecule	M01AB15|S01BC05	74103-06-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OZWKMVRBQXNZKK-UHFFFAOYSA-N
7207	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Padi SS (2004)	15102535	176262	457	Ketorolac	Ketorolacum|Ketorolaco|Ktorolac|(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid|rac-Ketorolac|(+-)-Ketorolac|Ketorolac	toradol|acular ls|toradol tab 	DRUGBANK	DB00465	C15H13NO3	small molecule	M01AB15|S01BC05	74103-06-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OZWKMVRBQXNZKK-UHFFFAOYSA-N
7208	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hoecherl K (2002)	12110513	176263	457	Ketorolac	Ketorolacum|Ketorolaco|Ktorolac|(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid|rac-Ketorolac|(+-)-Ketorolac|Ketorolac	toradol|acular ls|toradol tab 	DRUGBANK	DB00465	C15H13NO3	small molecule	M01AB15|S01BC05	74103-06-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OZWKMVRBQXNZKK-UHFFFAOYSA-N
7209	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ma W (2003)	14568029	176264	457	Ketorolac	Ketorolacum|Ketorolaco|Ktorolac|(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid|rac-Ketorolac|(+-)-Ketorolac|Ketorolac	toradol|acular ls|toradol tab 	DRUGBANK	DB00465	C15H13NO3	small molecule	M01AB15|S01BC05	74103-06-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OZWKMVRBQXNZKK-UHFFFAOYSA-N
7232	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7233	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Galvao RI (2005)	15756931	176291	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7234	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yamada M (1997)	9152412	176290	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7235	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yilmaz H (2005)	16245223	176292	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7236	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kothekar V (2001)	11563332	176288	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7237	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ozgocmen S (2005)	15943176	176289	461	Tenoxicam	Tenoxicamum|Tnoxicam|Tenoxicam	tenoxicam tablets|tenoxicam-20	DRUGBANK	DB00469	C13H11N3O4S2	small molecule	M01AC02	59804-37-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZNWYQJJBLGYLT-UHFFFAOYSA-N
7368	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	negative modulator	target	Payvandi F (2004)	15598423	176374	472	Lenalidomide	1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline|IMid-1|CC-5013|IMiD3|Revlimid|3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione|CDC 501	revlimid	DRUGBANK	DB00480	C13H13N3O3	small molecule	L04AX04	191732-72-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GOTYRUGSSMKFNF-UHFFFAOYSA-N
7369	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	negative modulator	target	Zeldis JB (2003)	12720152	176373	472	Lenalidomide	1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline|IMid-1|CC-5013|IMiD3|Revlimid|3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione|CDC 501	revlimid	DRUGBANK	DB00480	C13H13N3O3	small molecule	L04AX04	191732-72-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GOTYRUGSSMKFNF-UHFFFAOYSA-N
7390	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7391	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ahmad SR (2002)	12093311	176398	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7392	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Scheiman JM (2002)	12086292	176394	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7393	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Reddy BS (2002)	12086402	176395	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7394	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Lu S (2002)	12104042	176396	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7395	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Sigthorsson G (2002)	12055598	176397	474	Celecoxib	P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide|Celecoxibum|Celecoxib|Celebrex|Clcoxib	lupin-celecoxib|bio-celecoxib|	DRUGBANK	DB00482	C17H14F3N3O2S	small molecule	L01XX33|M01AH01	169590-42-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZEKVGVHFLEQIL-UHFFFAOYSA-N
7498	112874	7015	-	TERT	CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT	9606	Homo sapiens	inhibitor	target	Leeansyah E (2013)	23303810	176483	487	Zidovudine	AZT|ZDV|Azidothymidine|Zidovudin|Zidovudinum	trizivir|retrovir (azt)|apo-la	DRUGBANK	DB00495	C10H13N5O4	small molecule	J05AR01|J05AF01|J05AR05|J05AR04	30516-87-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBOMLICNUCNMMY-XLPZGREQSA-N
7537	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7538	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kennedy JH (2003)	14613550	176516	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7539	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Capasso A (1997)	9253954	176515	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7540	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Burdan F (2004)	15458776	176519	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7541	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Capasso A (1999)	10465690	176518	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7542	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kirkova M (2007)	17391279	176520	492	Tolmetin	Tolmetina|1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid|Tolmetino|5-(P-Toluoyl)-1-methylpyrrole-2-acetic acid|1-Methyl-5-P-toluoylpyrrole-2-acetic acid|Tolmetin|Tolmtine|Tolmetinum	tolectin 400 cap 400mg|tolmeti	DRUGBANK	DB00500	C15H15NO3	small molecule	M01AB03|M02AA21	26171-23-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UPSPUYADGBWSHF-UHFFFAOYSA-N
7624	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	antagonist	target	Tran-Thang C (1994)	7962113	176574	503	Aminocaproic Acid	Aminocapronsure|Acidum Aminocaproicum|6-aminohexanoic acid|Z|Epsicaprom|Epsilon-Aminocaproic Acid|Aminocaproic acid|epsilon-Aminohexanoic acid|epsilon-Ahx|Epsilcapramine|Aminohexanoic acid|EACA|Caproamin|AMICAR|6-Aminocaproic acid|Acide aminocaproque|Ahx|cido aminocaprico|Acide aminocaproque|Eaca|AMINOCAPROIC	exoden white tooth|amicar|amin	DRUGBANK	DB00513	C6H13NO2	small molecule	B02AA01	60-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLXKOJJOQWFEFD-UHFFFAOYSA-N
7625	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	antagonist	target	Urano T (1988)	3146348	176575	503	Aminocaproic Acid	Aminocapronsure|Acidum Aminocaproicum|6-aminohexanoic acid|Z|Epsicaprom|Epsilon-Aminocaproic Acid|Aminocaproic acid|epsilon-Aminohexanoic acid|epsilon-Ahx|Epsilcapramine|Aminohexanoic acid|EACA|Caproamin|AMICAR|6-Aminocaproic acid|Acide aminocaproque|Ahx|cido aminocaprico|Acide aminocaproque|Eaca|AMINOCAPROIC	exoden white tooth|amicar|amin	DRUGBANK	DB00513	C6H13NO2	small molecule	B02AA01	60-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLXKOJJOQWFEFD-UHFFFAOYSA-N
7626	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	antagonist	target	Husain SS (1989)	2502209	176576	503	Aminocaproic Acid	Aminocapronsure|Acidum Aminocaproicum|6-aminohexanoic acid|Z|Epsicaprom|Epsilon-Aminocaproic Acid|Aminocaproic acid|epsilon-Aminohexanoic acid|epsilon-Ahx|Epsilcapramine|Aminohexanoic acid|EACA|Caproamin|AMICAR|6-Aminocaproic acid|Acide aminocaproque|Ahx|cido aminocaprico|Acide aminocaproque|Eaca|AMINOCAPROIC	exoden white tooth|amicar|amin	DRUGBANK	DB00513	C6H13NO2	small molecule	B02AA01	60-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLXKOJJOQWFEFD-UHFFFAOYSA-N
7627	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	antagonist	target	Krishnamurti C (1994)	8073394	176573	503	Aminocaproic Acid	Aminocapronsure|Acidum Aminocaproicum|6-aminohexanoic acid|Z|Epsicaprom|Epsilon-Aminocaproic Acid|Aminocaproic acid|epsilon-Aminohexanoic acid|epsilon-Ahx|Epsilcapramine|Aminohexanoic acid|EACA|Caproamin|AMICAR|6-Aminocaproic acid|Acide aminocaproque|Ahx|cido aminocaprico|Acide aminocaproque|Eaca|AMINOCAPROIC	exoden white tooth|amicar|amin	DRUGBANK	DB00513	C6H13NO2	small molecule	B02AA01	60-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLXKOJJOQWFEFD-UHFFFAOYSA-N
7762	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Bulgaru AM (2003)	12820772	176686	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7763	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Kim TE (2002)	12498017	176687	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7764	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Akita RW (2003)	12840797	176684	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7765	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Laird AD (2003)	12517254	176685	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7766	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Delbaldo C (2003)	12814826	176683	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7767	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7774	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Malmstrom K (1999)	10566562	176707	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7775	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Matheson AJ (2001)	11398914	176706	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7776	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Langman MJ (1999)	10580458	176705	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7777	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chakraborti AK (2010)	20166930	176704	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7778	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ashok V (2011)	20724158	176703	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7779	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Baron JA (2008)	18922570	176702	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7780	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7781	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Pascucci RA (1999)	10643177	176709	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7782	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hawkey C (2000)	10693877	176708	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7783	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ehrich EW (1999)	10555907	176710	523	Rofecoxib	-	vioxx tab 25mg|vioxx suspensio	DRUGBANK	DB00533	C17H14O4S	small molecule	M01AH02	162011-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZJQGNCSTQAWON-UHFFFAOYSA-N
7999	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Fukuda M (2006)	16959356	176837	541	Acetohydroxamic Acid	Acethydroxamsaeure|Acetohydroxamic acid|Acethydroxamsaure|AHA|Acetyl hydroxyamino|Acidum acetohydroxamicum|Acetic acid, oxime|Acetohydroximic acid|N-Acetyl hydroxyacetamide|N-Acetylhydroxylamine|Acetylhydroxamic acid|Acetohydroxamate|Acido acetohidroxamico|Cetohyroxamic acid|Acide acetohydroxamique|Methylhydroxamic acid|Lithostat|N-Hydroxyacetamide	lithostat	DRUGBANK	DB00551	C2H5NO2	small molecule	G04BX03	546-88-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RRUDCFGSUDOHDG-UHFFFAOYSA-N
8000	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Bertini I (2007)	17269766	176836	541	Acetohydroxamic Acid	Acethydroxamsaeure|Acetohydroxamic acid|Acethydroxamsaure|AHA|Acetyl hydroxyamino|Acidum acetohydroxamicum|Acetic acid, oxime|Acetohydroximic acid|N-Acetyl hydroxyacetamide|N-Acetylhydroxylamine|Acetylhydroxamic acid|Acetohydroxamate|Acido acetohidroxamico|Cetohyroxamic acid|Acide acetohydroxamique|Methylhydroxamic acid|Lithostat|N-Hydroxyacetamide	lithostat	DRUGBANK	DB00551	C2H5NO2	small molecule	G04BX03	546-88-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RRUDCFGSUDOHDG-UHFFFAOYSA-N
8001	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Mannino C (2006)	16899369	176839	541	Acetohydroxamic Acid	Acethydroxamsaeure|Acetohydroxamic acid|Acethydroxamsaure|AHA|Acetyl hydroxyamino|Acidum acetohydroxamicum|Acetic acid, oxime|Acetohydroximic acid|N-Acetyl hydroxyacetamide|N-Acetylhydroxylamine|Acetylhydroxamic acid|Acetohydroxamate|Acido acetohidroxamico|Cetohyroxamic acid|Acide acetohydroxamique|Methylhydroxamic acid|Lithostat|N-Hydroxyacetamide	lithostat	DRUGBANK	DB00551	C2H5NO2	small molecule	G04BX03	546-88-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RRUDCFGSUDOHDG-UHFFFAOYSA-N
8002	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Bertini I (2005)	15809432	176838	541	Acetohydroxamic Acid	Acethydroxamsaeure|Acetohydroxamic acid|Acethydroxamsaure|AHA|Acetyl hydroxyamino|Acidum acetohydroxamicum|Acetic acid, oxime|Acetohydroximic acid|N-Acetyl hydroxyacetamide|N-Acetylhydroxylamine|Acetylhydroxamic acid|Acetohydroxamate|Acido acetohidroxamico|Cetohyroxamic acid|Acide acetohydroxamique|Methylhydroxamic acid|Lithostat|N-Hydroxyacetamide	lithostat	DRUGBANK	DB00551	C2H5NO2	small molecule	G04BX03	546-88-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RRUDCFGSUDOHDG-UHFFFAOYSA-N
8012	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8013	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Fackovcova D (2001)	11153163	176241	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8014	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Blanco FJ (1999)	10381057	176844	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8015	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Bugajski J (2001)	11785774	176845	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8016	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Raju J (2002)	11952155	176846	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8017	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Veiga AP (2004)	15464832	176843	544	Piroxicam	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid|Feldene|Pyroxycam|Piroxicam|Piroxicamum	feldene cap 20mg|nu-pirox cap 	DRUGBANK	DB00554	C15H13N3O4S	small molecule	M01AC01|M02AA07|S01BC06	36322-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYSPLQLAKJAUJT-UHFFFAOYSA-N
8115	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Martinez-Campa C (2006)	16555127	176947	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8116	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Duan L (2007)	17126817	176949	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8117	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Obey TB (2005)	16111654	176948	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8118	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Brantley-Finley C (2003)	12907245	176950	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8119	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Bene A (2004)	15498923	176951	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8176	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Poggi JC (2006)	17050798	176976	563	Fenoprofen	2-(3-phenoxyphenyl)propionic acid|Fenoprofen|(+/-)-m-phenoxyhydratropic acid|DL-2-(3-phenoxyphenyl)propionic acid|alpha-(m-Phenoxyphenyl)propionic acid|(+/-)-fenoprofen|Fenoprofeno|Fnoprofne|(+-)-2-(3-Phenoxyphenyl)propionic acid|3-phenoxyhydratropic acid|2-(m-phenoxyphenyl)propionic acid|Fenoprofenum|alpha-Methyl-3-phenoxybenzeneacetic acid	nalfon tab 600mg|fenoprofen|na	DRUGBANK	DB00573	C15H14O3	small molecule	M01AE04	29679-58-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RDJGLLICXDHJDY-UHFFFAOYSA-N
8219	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Talley JJ (2000)	10715145	177027	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8220	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hood WF (2003)	12644588	177026	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8221	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Jain KK (2000)	11060833	177030	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8222	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Gierse JK (2005)	15494548	177031	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8223	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8224	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Tacconelli S (2003)	12564662	177029	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8225	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yuan JJ (2002)	12167567	177028	570	Valdecoxib	-	-	DRUGBANK	DB00580	C16H14N2O3S	small molecule	M01AH03	181695-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LNPDTQAFDNKSHK-UHFFFAOYSA-N
8314	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kirchheiner J (2003)	12534640	177083	576	Diclofenac	2-((2,6-dichlorophenyl)amino)benzeneacetic acid|[2-(2,6-dichloroanilino)phenyl]acetic acid|Diclofenac Acid|Diclofenacum|Diclofenaco	dom-diclofenac|diclofenac sodi	DRUGBANK	DB00586	C14H11Cl2NO2	small molecule	D11AX18|S01BC03|M01AB55|M02AA15|S01CC01|M01AB05	15307-86-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCOPUUMXTXDBNB-UHFFFAOYSA-N
8315	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chavez ML (2003)	12852704	177085	576	Diclofenac	2-((2,6-dichlorophenyl)amino)benzeneacetic acid|[2-(2,6-dichloroanilino)phenyl]acetic acid|Diclofenac Acid|Diclofenacum|Diclofenaco	dom-diclofenac|diclofenac sodi	DRUGBANK	DB00586	C14H11Cl2NO2	small molecule	D11AX18|S01BC03|M01AB55|M02AA15|S01CC01|M01AB05	15307-86-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCOPUUMXTXDBNB-UHFFFAOYSA-N
8316	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Rowlinson SW (2003)	12925531	177102	576	Diclofenac	2-((2,6-dichlorophenyl)amino)benzeneacetic acid|[2-(2,6-dichloroanilino)phenyl]acetic acid|Diclofenac Acid|Diclofenacum|Diclofenaco	dom-diclofenac|diclofenac sodi	DRUGBANK	DB00586	C14H11Cl2NO2	small molecule	D11AX18|S01BC03|M01AB55|M02AA15|S01CC01|M01AB05	15307-86-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCOPUUMXTXDBNB-UHFFFAOYSA-N
8317	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Beubler E (2003)	12705061	177100	576	Diclofenac	2-((2,6-dichlorophenyl)amino)benzeneacetic acid|[2-(2,6-dichloroanilino)phenyl]acetic acid|Diclofenac Acid|Diclofenacum|Diclofenaco	dom-diclofenac|diclofenac sodi	DRUGBANK	DB00586	C14H11Cl2NO2	small molecule	D11AX18|S01BC03|M01AB55|M02AA15|S01CC01|M01AB05	15307-86-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCOPUUMXTXDBNB-UHFFFAOYSA-N
8318	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Blomme EA (2003)	12588370	177101	576	Diclofenac	2-((2,6-dichlorophenyl)amino)benzeneacetic acid|[2-(2,6-dichloroanilino)phenyl]acetic acid|Diclofenac Acid|Diclofenacum|Diclofenaco	dom-diclofenac|diclofenac sodi	DRUGBANK	DB00586	C14H11Cl2NO2	small molecule	D11AX18|S01BC03|M01AB55|M02AA15|S01CC01|M01AB05	15307-86-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCOPUUMXTXDBNB-UHFFFAOYSA-N
8407	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Cejkova J (2005)	15866288	177159	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8408	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Jankun J (2001)	11562773	177158	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8409	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8410	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Luikart S (2002)	12183060	177160	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8411	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Chen YX (2003)	12897821	177161	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8412	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	inhibitor	target	Vakili J (2001)	11544332	177162	584	Amiloride	Amilorida|Amiloridum|Amilorid|Amyloride|N-amidino-3,5-diamino-6-chloropyrazinecarboxamide|Amipramidine|Amipramidin|3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide	amiloride hydrocloride|amilori	DRUGBANK	DB00594	C6H8ClN7O	small molecule	C03DB01	2609-46-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSDQTOBWRPYKKA-UHFFFAOYSA-N
8550	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2001)	11245463	177238	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8551	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2004)	15548677	177239	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8552	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2003)	12566304	177235	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8553	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Pangburn HA (2005)	16138927	177236	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8554	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2006)	16546990	177237	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8560	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Giuliano F (1999)	10372826	177229	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8561	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yip-Schneider MT (2000)	10657949	177245	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8562	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Fosslien E (2000)	11078056	177244	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8563	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Molina MA (1999)	10485483	177247	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8564	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Taylor MT (2000)	11118042	177246	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8577	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Jang CH (2006)	16418198	177263	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8578	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Dias-Melicio LA (2007)	17456179	177260	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8579	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Lim EJ (2006)	16870179	177261	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8580	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Rachmilewitz D (2006)	16670522	177259	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8581	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Wozniacka A (2006)	16761500	177262	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
9205	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antagonist	target	van der Poll T (1996)	8609227	177679	658	Epinephrine	(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol|Epinefrin|Epinephrinum|(-)-(R)-Epinephrine|4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol|L-Adrenaline|(R)-()-adrenaline|Epinephrine|Epinefrina|Primatene|()-adrenaline|(R)-(-)-Adrenaline|Adrenaline|(-)-Adrenaline|(R)-(-)-Epirenamine|levoepinephrine|(R)-(-)-Adnephrine|Epinephrin|Adrenalin|(R)-(-)-Epinephrine	dentsply 2% lidocaine with epi	DRUGBANK	DB00668	C9H13NO3	small molecule	A01AD01|B02BC09|C01CA24|S01EA01|R03AA01|R03AK01|S01EA51|R01AA14	51-43-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UCTWMZQNUQWSLP-VIFPVBQESA-N
9488	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	antagonist	target	Zugmaier G (2000)	10667230	177811	676	Pentosan Polysulfate	Pentosane polysulfate|Pentosanpolysulfat|Pentosan sulfuric polyester|Pentosano polisulfato|Pentosani polysulfas	elmiron	DRUGBANK	DB00686	C10H18O21S4	small molecule	C05BA04|G04BX15	37300-21-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCNSUIJIOOXEZ-SJYYZXOBSA-N
9489	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	antagonist	target	Pluda JM (1993)	7692072	177812	676	Pentosan Polysulfate	Pentosane polysulfate|Pentosanpolysulfat|Pentosan sulfuric polyester|Pentosano polisulfato|Pentosani polysulfas	elmiron	DRUGBANK	DB00686	C10H18O21S4	small molecule	C05BA04|G04BX15	37300-21-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCNSUIJIOOXEZ-SJYYZXOBSA-N
9490	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	antagonist	target	Mucha S (2002)	12375053	177813	676	Pentosan Polysulfate	Pentosane polysulfate|Pentosanpolysulfat|Pentosan sulfuric polyester|Pentosano polisulfato|Pentosani polysulfas	elmiron	DRUGBANK	DB00686	C10H18O21S4	small molecule	C05BA04|G04BX15	37300-21-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCNSUIJIOOXEZ-SJYYZXOBSA-N
9491	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	antagonist	target	Jerebtsova M (2007)	17071728	177814	676	Pentosan Polysulfate	Pentosane polysulfate|Pentosanpolysulfat|Pentosan sulfuric polyester|Pentosano polisulfato|Pentosani polysulfas	elmiron	DRUGBANK	DB00686	C10H18O21S4	small molecule	C05BA04|G04BX15	37300-21-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCNSUIJIOOXEZ-SJYYZXOBSA-N
9492	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	antagonist	target	McLeskey SW (1996)	8738610	177808	676	Pentosan Polysulfate	Pentosane polysulfate|Pentosanpolysulfat|Pentosan sulfuric polyester|Pentosano polisulfato|Pentosani polysulfas	elmiron	DRUGBANK	DB00686	C10H18O21S4	small molecule	C05BA04|G04BX15	37300-21-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCCNSUIJIOOXEZ-SJYYZXOBSA-N
9720	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Bayly CI (1999)	10091674	177979	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9721	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hinz B (2001)	11405284	177978	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9722	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	van Haeringen NJ (2000)	10977131	177980	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9723	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Nivsarkar M (2008)	19066416	177973	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9724	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Smith T (2000)	11006278	160486	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9725	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hewett SJ (2000)	10773011	177971	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
9726	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Basselin M (2007)	17562170	177977	702	Flurbiprofen	Flurbiprofenum|3-Fluoro-4-phenylhydratropic acid|S-flurbiprofen|2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid|(+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid|2-(2-Fluorobiphenyl-4-yl)propanoic acid|Flurbiprofen|Flurbiprofeno|FLP|Ansaid|Flurbiprofene	nu-flurbiprofen tab 50mg|ratio	DRUGBANK	DB00712	C15H13FO2	small molecule	M02AA19|S01BC04|M01AE09|R02AX01	5104-49-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SYTBZMRGLBWNTM-UHFFFAOYSA-N
10061	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen WS (2001)	11275997	178176	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10062	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Svendsen KB (2000)	11009046	178174	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10063	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kusuhara H (1999)	10594327	178175	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10064	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen WS (2003)	12824918	178173	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10065	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wilson JE (2004)	15198222	178171	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10066	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	739	Etodolac	Etodolac|(1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid|todolac|1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid|1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid|Etodolaco|Etodolacum|Etodolsure|Etodolic acid|(+-)-1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid|1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid	taro-etodolac 200 mg|etodolac|	DRUGBANK	DB00749	C17H21NO3	small molecule	M01AB08	41340-25-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNYBQONXHNTVIJ-UHFFFAOYSA-N
10426	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Bhat AS (2005)	15792781	65577	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10427	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Walton LJ (1999)	10393680	178381	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10428	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Gierse JK (1995)	7832763	178380	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10429	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10430	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Bhat AS (2007)	17150210	178382	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10431	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Cryer B (1998)	9626023	178378	774	Mefenamic acid	CN 35355|CN-35355|Mefenaminsaeure|Acidum mefenamicum|Acido mefenamico|Mefenaminsure|INF-3355|INF 3355|N-(2,3-Xylyl)-2-aminobenzoic acid|Ponstel|N-2,3-Xylylanthranilic acid|Acide mfnamique|CI-473	mefenamic acid|nu-mefenamic 25	DRUGBANK	DB00784	C15H15NO2	small molecule	M01AG01	61-68-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYYBABOKPJLUIN-UHFFFAOYSA-N
10444	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10445	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Shinoda K (2003)	12527923	178389	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10446	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Bernardo MM (2002)	11790786	178388	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10447	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10448	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Bourd-Boittin K (2005)	15748894	178385	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10449	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Fanchon S (2004)	15056115	178387	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10450	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Treharne GD (1999)	10460642	178386	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10451	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Nenan S (2007)	17234180	178390	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10452	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Underwood CK (2003)	12763661	178391	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10453	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10456	110462	4319	-	MMP10	SL-2|STMY2	9606	Homo sapiens	antagonist	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10457	110462	4319	-	MMP10	SL-2|STMY2	9606	Homo sapiens	antagonist	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10466	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10467	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10470	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10471	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10472	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10477	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10478	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10483	110466	4323	-	MMP14	MMP-14|MMP-X1|MT-MMP|MT-MMP 1|MT1-MMP|MT1MMP|MTMMP1|WNCHRS	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10484	110466	4323	-	MMP14	MMP-14|MMP-X1|MT-MMP|MT-MMP 1|MT1-MMP|MT1MMP|MTMMP1|WNCHRS	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10501	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Dhir A (2007)	17604186	178398	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10502	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	White WB (2007)	17612049	178399	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10503	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10504	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hassan-Alin M (2007)	17532719	178402	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10505	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kumar P (2007)	17521299	178400	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10506	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Albertini R (2007)	17607546	178401	778	Naproxen	(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid|(+)-(S)-Naproxen|Naproxne|Naproxeno|(+)-Naproxen|Naproxenum|(S)-(+)-Naproxen|(+)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionic acid|(+)-(S)-6-Methoxy--methyl-2-naphthaleneacetic acid|(S)-Naproxen|(S)-2-(6-Methoxy-2-naphthyl)propionic acid|(+)-2-(Methoxy-2-naphthyl)-propionsure|Naproxen|Naprolag|(S)-2-(6-Methoxy-2-naphthyl)propanoic acid|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid	ntp-naproxen sodium|naprosyn 5	DRUGBANK	DB00788	C14H14O3	small molecule	M01AE56|G02CC02|M02AA12|M01AE52|M01AE02	22204-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWTZPSULFXXJA-VIFPVBQESA-N
10562	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10563	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10564	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Cipolla G (2002)	12208114	174550	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10565	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Generini S (2002)	12463455	174551	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10566	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Mifflin RC (2004)	14742690	174552	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10567	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Pruzanski W (1997)	9256165	174553	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10568	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Distrutti E (2006)	16855178	174554	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10755	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Takada Y (2004)	15489888	178495	802	Phenylbutazone	Phenylbutazon|3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine|Phenylbutazonum|4-BUTYL-1,2-diphenyl-pyrazolidine-3,5-dione|Phenylbutazone|Phenbutazone|4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione|Fenilbutazona	alka phenyl tab|novo-butazone 	DRUGBANK	DB00812	C19H20N2O2	small molecule	M01AA01|M02AA01|M01BA01	50-33-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VYMDGNCVAMGZFE-UHFFFAOYSA-N
10756	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Arifah AK (2002)	12213119	178494	802	Phenylbutazone	Phenylbutazon|3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine|Phenylbutazonum|4-BUTYL-1,2-diphenyl-pyrazolidine-3,5-dione|Phenylbutazone|Phenbutazone|4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione|Fenilbutazona	alka phenyl tab|novo-butazone 	DRUGBANK	DB00812	C19H20N2O2	small molecule	M01AA01|M02AA01|M01BA01	50-33-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VYMDGNCVAMGZFE-UHFFFAOYSA-N
10757	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	802	Phenylbutazone	Phenylbutazon|3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine|Phenylbutazonum|4-BUTYL-1,2-diphenyl-pyrazolidine-3,5-dione|Phenylbutazone|Phenbutazone|4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione|Fenilbutazona	alka phenyl tab|novo-butazone 	DRUGBANK	DB00812	C19H20N2O2	small molecule	M01AA01|M02AA01|M01BA01	50-33-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VYMDGNCVAMGZFE-UHFFFAOYSA-N
10758	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Beretta C (2005)	15939622	178489	802	Phenylbutazone	Phenylbutazon|3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine|Phenylbutazonum|4-BUTYL-1,2-diphenyl-pyrazolidine-3,5-dione|Phenylbutazone|Phenbutazone|4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione|Fenilbutazona	alka phenyl tab|novo-butazone 	DRUGBANK	DB00812	C19H20N2O2	small molecule	M01AA01|M02AA01|M01BA01	50-33-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VYMDGNCVAMGZFE-UHFFFAOYSA-N
10775	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Tegeder I (1999)	10340919	178510	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10776	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Poulsen Nautrup B (1999)	10220944	178511	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10777	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10778	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Blanco FJ (1999)	10381057	176844	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10779	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Gross JM (1999)	10567199	178509	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10780	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Panara MR (1999)	10381787	178508	804	Meloxicam	Mloxicam|Meloxicamum|UNII-vg2qf83cgl|Mobic|Meloxicam	ava-meloxicam|auro-meloxicam|a	DRUGBANK	DB00814	C14H13N3O4S2	small molecule	M01AC56|M01AC06	71125-38-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
10827	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wilson JE (2004)	15198222	178171	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
10828	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
10829	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Brideau C (2001)	11703020	178550	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
10830	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Narlawar R (2006)	17181139	178551	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
10831	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kay-Mugford P (2000)	10895904	178552	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
10832	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Beretta C (2005)	15939622	178489	811	Carprofen	(+-)-6-chloro-alpha-Methylcarbazole-2-acetic acid|Carprofeno|2-(6-Chloro-9H-carbazol-2-yl)-propionic acid|6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid|Carprofne|Carprofen|Carprofenum|(+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid	-	DRUGBANK	DB00821	C15H12ClNO2	small molecule	-	53716-49-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUXBGTOOZJQSKH-UHFFFAOYSA-N
11173	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11174	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11181	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Wu Z (2014)	24365491	178701	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11182	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11216	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Cappon GD (2003)	12852483	178741	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11217	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11218	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Young JM (1996)	8737748	178742	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11219	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Jeske AH (1999)	10825891	178745	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11220	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Mao H (2001)	11673972	178744	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11221	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Moore PA (2001)	11315375	178743	851	Diflunisal	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid|Dolobid|Diflunisalum|5-(2,4-Difluorophenyl)salicylic acid|2-(Hydroxy)-5-(2,4-difluorophenyl)benzoic acid|Diflunisal	diflunisal-500 - tab 500mg|nu-	DRUGBANK	DB00861	C13H8F2O3	small molecule	N02BA11	22494-42-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUPFGZXOMWLGNK-UHFFFAOYSA-N
11281	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	860	Suprofen	alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid|Suprofenum|2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid|Suprofne|2-(4-(2-Thenoyl)phenyl)propionsaeure|4-(2-Thenoyl)hydratropsaeure|Suprofene|SUTOPROFEN|(+-)-2-(P-(2-Thenoyl)phenyl)propionic acid|P-2-Thenoylhydratropic acid|Suprofeno|Suprofen|PROFENAL	-	DRUGBANK	DB00870	C14H12O3S	small molecule	M01AE07	40828-46-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDKGKXOCJGEUJW-UHFFFAOYSA-N
11282	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Llorens O (2002)	11885959	178800	860	Suprofen	alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid|Suprofenum|2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid|Suprofne|2-(4-(2-Thenoyl)phenyl)propionsaeure|4-(2-Thenoyl)hydratropsaeure|Suprofene|SUTOPROFEN|(+-)-2-(P-(2-Thenoyl)phenyl)propionic acid|P-2-Thenoylhydratropic acid|Suprofeno|Suprofen|PROFENAL	-	DRUGBANK	DB00870	C14H12O3S	small molecule	M01AE07	40828-46-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDKGKXOCJGEUJW-UHFFFAOYSA-N
11283	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	860	Suprofen	alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid|Suprofenum|2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid|Suprofne|2-(4-(2-Thenoyl)phenyl)propionsaeure|4-(2-Thenoyl)hydratropsaeure|Suprofene|SUTOPROFEN|(+-)-2-(P-(2-Thenoyl)phenyl)propionic acid|P-2-Thenoylhydratropic acid|Suprofeno|Suprofen|PROFENAL	-	DRUGBANK	DB00870	C14H12O3S	small molecule	M01AE07	40828-46-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDKGKXOCJGEUJW-UHFFFAOYSA-N
11349	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Sehgal SN (2003)	12742462	178847	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11350	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Sehgal SN (2003)	12742462	178847	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11351	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11352	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Dowling RJ (2010)	20005306	178848	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11353	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Shuuin T (2009)	19620795	178849	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11869	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Zhang L (2007)	17369473	179062	904	Phenformin	DBI|Fenformin|Phenformine|-Phenethybiguanide|Fenformina|Phenforminum	-	DRUGBANK	DB00914	C10H15N5	small molecule	A10BD01|A10BA01	114-86-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ICFJFFQQTFMIBG-UHFFFAOYSA-N
11870	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Chen S (2008)	17995453	179061	904	Phenformin	DBI|Fenformin|Phenformine|-Phenethybiguanide|Fenformina|Phenforminum	-	DRUGBANK	DB00914	C10H15N5	small molecule	A10BD01|A10BA01	114-86-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ICFJFFQQTFMIBG-UHFFFAOYSA-N
11871	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Woollhead AM (2007)	17603555	179060	904	Phenformin	DBI|Fenformin|Phenformine|-Phenethybiguanide|Fenformina|Phenforminum	-	DRUGBANK	DB00914	C10H15N5	small molecule	A10BD01|A10BA01	114-86-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ICFJFFQQTFMIBG-UHFFFAOYSA-N
12105	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Graham GG (2004)	15035793	179201	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12106	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chae HJ (2004)	15106733	179207	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12107	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Fiebich BL (2004)	15070163	179206	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12108	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Vane JR (1971)	5284360	179204	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12109	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wu KK (2003)	15199473	179209	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12110	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Elvira C (2001)	15348270	179208	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
12131	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Narsinghani T (2006)	16290292	179228	929	Meclofenamic acid	N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid|Acide meclofenamique|Acidum meclofenamicum|Meclofenamate|N-(2,6-Dichloro-3-methylphenyl)anthranilic acid|INF 4668|N-(2,6-Dichloro-m-tolyl)anthranilic acid|CI-583|Acido meclofenamico	meclofenamate sodium	DRUGBANK	DB00939	C14H11Cl2NO2	small molecule	M01AG04|M02AA18	644-62-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SBDNJUWAMKYJOX-UHFFFAOYSA-N
12132	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kalgutkar AS (2000)	10639181	179223	929	Meclofenamic acid	N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid|Acide meclofenamique|Acidum meclofenamicum|Meclofenamate|N-(2,6-Dichloro-3-methylphenyl)anthranilic acid|INF 4668|N-(2,6-Dichloro-m-tolyl)anthranilic acid|CI-583|Acido meclofenamico	meclofenamate sodium	DRUGBANK	DB00939	C14H11Cl2NO2	small molecule	M01AG04|M02AA18	644-62-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SBDNJUWAMKYJOX-UHFFFAOYSA-N
12133	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wilson JE (2004)	15198222	178171	929	Meclofenamic acid	N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid|Acide meclofenamique|Acidum meclofenamicum|Meclofenamate|N-(2,6-Dichloro-3-methylphenyl)anthranilic acid|INF 4668|N-(2,6-Dichloro-m-tolyl)anthranilic acid|CI-583|Acido meclofenamico	meclofenamate sodium	DRUGBANK	DB00939	C14H11Cl2NO2	small molecule	M01AG04|M02AA18	644-62-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SBDNJUWAMKYJOX-UHFFFAOYSA-N
12134	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Traupe T (2002)	12409963	179227	929	Meclofenamic acid	N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid|Acide meclofenamique|Acidum meclofenamicum|Meclofenamate|N-(2,6-Dichloro-3-methylphenyl)anthranilic acid|INF 4668|N-(2,6-Dichloro-m-tolyl)anthranilic acid|CI-583|Acido meclofenamico	meclofenamate sodium	DRUGBANK	DB00939	C14H11Cl2NO2	small molecule	M01AG04|M02AA18	644-62-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SBDNJUWAMKYJOX-UHFFFAOYSA-N
12135	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Smith WL (1994)	7825862	179226	929	Meclofenamic acid	N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid|Acide meclofenamique|Acidum meclofenamicum|Meclofenamate|N-(2,6-Dichloro-3-methylphenyl)anthranilic acid|INF 4668|N-(2,6-Dichloro-m-tolyl)anthranilic acid|CI-583|Acido meclofenamico	meclofenamate sodium	DRUGBANK	DB00939	C14H11Cl2NO2	small molecule	M01AG04|M02AA18	644-62-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SBDNJUWAMKYJOX-UHFFFAOYSA-N
12156	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	acetylation	target	Alfonso LF (2009)	21475861	179244	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12164	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	activator	target	Din FV (2012)	22406476	179247	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12165	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	activator	target	Hawley SA (2012)	22517326	179246	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12168	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Din FV (2012)	22406476	179247	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12169	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator	target	Hawley SA (2012)	22517326	179246	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12173	110858	4791	-	NFKB2	CVID10|H2TF1|LYT-10|LYT10|NF-kB2|p100|p52	9606	Homo sapiens	antagonist	target	Kopp E (1994)	8052854	179249	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12174	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Kopp E (1994)	8052854	179249	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12176	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	unknown	target	Yin MJ (1998)	9817203	179251	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12177	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Shen J (2006)	17181859	179252	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12178	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Nakano M (2007)	17258197	179253	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12179	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wang HJ (2006)	17037745	179254	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12180	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hall MN (2007)	17301265	179255	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12181	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Brzozowski T (2006)	17033106	179256	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12182	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12183	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	unknown	target	Stevenson MA (1999)	10553090	179248	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12330	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Sanchez-Matienzo D (2006)	16982289	179368	953	Bromfenac	Bromfenaco|2-amino-3-(4-Bromobenzoyl)benzeneacetic acid|[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid|Bromfenacum	prolensa|bromsite 0.075%|bromd	DRUGBANK	DB00963	C15H12BrNO3	small molecule	S01BC11	91714-94-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
12331	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Waterbury LD (2006)	16846546	179366	953	Bromfenac	Bromfenaco|2-amino-3-(4-Bromobenzoyl)benzeneacetic acid|[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid|Bromfenacum	prolensa|bromsite 0.075%|bromd	DRUGBANK	DB00963	C15H12BrNO3	small molecule	S01BC11	91714-94-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
12332	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chitturi S (2002)	12016548	179367	953	Bromfenac	Bromfenaco|2-amino-3-(4-Bromobenzoyl)benzeneacetic acid|[2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid|Bromfenacum	prolensa|bromsite 0.075%|bromd	DRUGBANK	DB00963	C15H12BrNO3	small molecule	S01BC11	91714-94-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBPLOVFIXSTCRZ-UHFFFAOYSA-N
12565	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kawai S (1998)	9650852	159681	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12566	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yamazaki R (2002)	12065695	179564	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12567	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kawai S (1998)	9831331	179562	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12568	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ottonello L (2009)	19338579	179563	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12569	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yood MU (2006)	17024689	179560	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12570	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Zhou XP (2009)	19952416	179561	981	Oxaprozin	Duraprox|Walix|Daypro|Dayrun|Oxaprozinum|Danoprox|Oxaprozina|Deflam|Oxaprozine	apo-oxaprozin|rhoxal-oxaprozin	DRUGBANK	DB00991	C18H15NO3	small molecule	M01AE12	21256-18-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFPXSFXSNFPTHF-UHFFFAOYSA-N
12579	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Jeon KI (2003)	12754408	179568	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
12580	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Youn HS (2006)	17034761	179569	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
12703	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wilson JE (2004)	15198222	178171	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12704	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Zuniga J (2003)	14513718	179627	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12705	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Sommerauer M (2001)	11729362	179635	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12706	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Levoin N (2002)	11814865	179634	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12707	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12708	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kay-Mugford P (2000)	10895904	178552	999	Ketoprofen	m-Benzoylhydratropic acid|3-Benzoyl--methylbenzeneacetic acid|3-Benzoyl-alpha-methylbenzeneacetic acid|2-(3-Benzoylphenyl)propionic acid|Ketoprofen|3-Benzoylhydratropic acid|Orudis (tn)|L'Acide (benzoyl-3-phenyl)-2-propionique	nu-ketoprofen-e ect 50mg|orudi	DRUGBANK	DB01009	C16H14O3	small molecule	M01AE53|M01AE03|M02AA10	22071-15-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DKYWVDODHFEZIM-UHFFFAOYSA-N
12745	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12746	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Stolfi C (2008)	17981262	179660	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12747	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12748	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12749	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wiggins JB (2009)	19743890	179656	1004	Balsalazide	Balsalazida|Balsalazido|(e)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid|Balsalazidum|5-[4-(2-Carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid|(e)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid|3-(2-{4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid	balsalazide disodium|colazal|g	DRUGBANK	DB01014	C17H15N3O6	small molecule	A07EC04	80573-04-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IPOKCKJONYRRHP-FMQUCBEESA-N
12797	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Steinmeyer J (1998)	9413935	179698	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12798	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Sadowski T (2001)	11246672	179699	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12799	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Amin AR (1996)	8943052	179700	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12800	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Oringer RJ (2002)	12211491	179701	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12802	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Yao JS (2004)	15256478	179704	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12803	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Sasamura H (2002)	11875741	179702	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12804	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Rocchetti R (2005)	16224178	179703	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12820	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Koistinaho M (2005)	15674236	179720	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12821	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Sutton TA (2005)	15353401	179721	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12822	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Brundula V (2002)	12023318	179717	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12823	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Lee CZ (2006)	16395286	179719	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12824	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Machado LS (2006)	16846501	179718	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12945	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Zhu ZS (2004)	15133856	179770	1018	Irbesartan	2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one|Irbesartan|Avapro|BMS 186295	ipg-irbesartan|dom-irbesartan|	DRUGBANK	DB01029	C25H28N6O	small molecule	C09DA04|C09CA04|C09DB05	138402-11-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YOSHYTLCDANDAN-UHFFFAOYSA-N
12946	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Cheng SM (2004)	15210574	179769	1018	Irbesartan	2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one|Irbesartan|Avapro|BMS 186295	ipg-irbesartan|dom-irbesartan|	DRUGBANK	DB01029	C25H28N6O	small molecule	C09DA04|C09CA04|C09DB05	138402-11-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YOSHYTLCDANDAN-UHFFFAOYSA-N
13085	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13086	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Yasui K (2005)	15723633	179849	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13090	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13091	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Richardson P (2002)	12046682	179856	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13092	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Fu LM (2002)	12102294	179854	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13093	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Vescovo G (2002)	12167383	179855	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13094	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Enomoto N (2002)	12105857	179852	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13095	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Rajkumar SV (2001)	12113124	179853	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13096	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Turk BE (1996)	8755512	179851	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13098	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Kim JH (2011)	21507989	179857	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13099	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Payvandi F (2004)	15598423	176374	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13100	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Hada M (2004)	15446566	179858	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13101	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Horrobin DF (2003)	12710892	179859	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13102	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Wiedmann MW (2005)	15892618	179861	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13103	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	antagonist	target	Du GJ (2005)	15982930	179860	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13285	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	negative modulator	target	Palayoor ST (2012)	22668799	179903	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13289	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chavez ML (2003)	12852704	177085	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13290	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13291	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Gallego-Sandin S (2004)	15481334	179907	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13292	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Murphey LJ (2004)	15494133	179908	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13293	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ouellet M (2004)	14510637	179909	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13294	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Sanchez-Fidalgo S (2004)	15556152	179910	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13308	112251	6347	-	CCL2	GDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF	9606	Homo sapiens	inhibitor	target	Frydas S (2005)	15698514	179916	1043	Mimosine	Leucaenine|Leucenine|Leucaenol|Mimosin|(S)-2-Amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate|Leucenol|L-Mimosine	-	DRUGBANK	DB01055	C8H10N2O4	small molecule	-	500-44-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WZNJWVWKTVETCG-YFKPBYRVSA-N
13309	112251	6347	-	CCL2	GDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF	9606	Homo sapiens	inhibitor	target	Conti P (2002)	11936838	179915	1043	Mimosine	Leucaenine|Leucenine|Leucaenol|Mimosin|(S)-2-Amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate|Leucenol|L-Mimosine	-	DRUGBANK	DB01055	C8H10N2O4	small molecule	-	500-44-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WZNJWVWKTVETCG-YFKPBYRVSA-N
13356	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Dubey RK (2004)	15292328	179944	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13357	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Oudit GY (2003)	12963636	179940	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13358	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Vaniotis G (2011)	20732414	179941	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13359	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Azzi M (2003)	13679574	179942	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13360	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Yeh CK (2005)	15689414	179943	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13361	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Adissu HA (2004)	15138589	179939	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13389	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	unknown	target	Hardeland R (2009)	19449447	179953	1053	Melatonin	5-methoxy-N-acetyltryptamine|Melatonin|N-Acetyl-5-methoxytryptamine|Melatonine|N-[2-(5-methoxyindol-3-yl)ethyl]acetamide	-	DRUGBANK	DB01065	C13H16N2O2	small molecule	N05CH01	73-31-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DRLFMBDRBRZALE-UHFFFAOYSA-N
13390	107262	811	-	CALR	CRT|HEL-S-99n|RO|SSA|cC1qR	9606	Homo sapiens	unknown	target	Macias M (2003)	12603316	179957	1053	Melatonin	5-methoxy-N-acetyltryptamine|Melatonin|N-Acetyl-5-methoxytryptamine|Melatonine|N-[2-(5-methoxyindol-3-yl)ethyl]acetamide	-	DRUGBANK	DB01065	C13H16N2O2	small molecule	N05CH01	73-31-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DRLFMBDRBRZALE-UHFFFAOYSA-N
13647	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Nichols WW (1991)	1717784	180082	1076	Iloprost	-	ventavis	DRUGBANK	DB01088	C22H32O4	small molecule	B01AC11	78919-13-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIFJCPQKFCZDDL-ACWOEMLNSA-N
13648	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Kerins DM (1992)	1370924	180081	1076	Iloprost	-	ventavis	DRUGBANK	DB01088	C22H32O4	small molecule	B01AC11	78919-13-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIFJCPQKFCZDDL-ACWOEMLNSA-N
13649	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Herczenik E (2007)	17510465	180079	1076	Iloprost	-	ventavis	DRUGBANK	DB01088	C22H32O4	small molecule	B01AC11	78919-13-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIFJCPQKFCZDDL-ACWOEMLNSA-N
13650	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Nicolini FA (1990)	1689620	180083	1076	Iloprost	-	ventavis	DRUGBANK	DB01088	C22H32O4	small molecule	B01AC11	78919-13-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIFJCPQKFCZDDL-ACWOEMLNSA-N
13651	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Nizankowski R (1991)	1726988	180080	1076	Iloprost	-	ventavis	DRUGBANK	DB01088	C22H32O4	small molecule	B01AC11	78919-13-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIFJCPQKFCZDDL-ACWOEMLNSA-N
13961	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Mamputu JC (2004)	14746574	180261	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13962	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Kimura T (2007)	17602961	180260	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13963	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Mamputu JC (2002)	12126787	180263	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13964	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Li L (2006)	17046555	180262	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
14066	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	de Boer RA (2001)	11378004	180311	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14067	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Shyu KG (2005)	15732037	180310	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14068	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Shyu KG (2005)	15942707	180313	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14069	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Saijonmaa O (2004)	15071347	180312	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14070	113255	7412	-	VCAM1	CD106|INCAM-100	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14071	113255	7412	-	VCAM1	CD106|INCAM-100	9606	Homo sapiens	inhibitor	target	Chen JW (2004)	15374848	180314	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14072	113255	7412	-	VCAM1	CD106|INCAM-100	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14398	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Kietzmann T (2003)	12637567	180441	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14399	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Li J (2003)	12547826	180437	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14400	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Dong Z (2002)	12426127	180438	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14401	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Drobna Z (2003)	12475910	180439	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14402	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Muscarella DE (2002)	12075113	180440	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14403	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Dong Z (2002)	12426127	180438	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14404	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	He Z (2003)	12529330	180442	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14411	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Fauconneau B (2002)	12472888	180444	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14412	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Tanaka-Kagawa T (2003)	14674888	180447	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14413	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Jung DK (2003)	14516795	180449	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14414	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Mousa SA (2007)	17158527	180448	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14415	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Felix K (2005)	15849723	180450	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14416	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Chen X (2002)	11752352	171740	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14417	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2007)	17450217	180452	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14418	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2005)	16230390	180453	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14419	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2006)	16387740	180451	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14720	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Williams RN (2005)	15993560	180580	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14721	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Brower GL (2007)	17308006	180581	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14722	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Reinhardt D (2002)	12381651	180579	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14723	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Okada M (2008)	19057128	180578	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14724	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Prontera C (1999)	10328230	180577	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14725	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Yamamoto D (2010)	20184869	180576	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14733	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Williams RN (2005)	15993560	180580	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14734	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Okada M (2008)	19057128	180578	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14735	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Yamamoto D (2008)	18501888	180584	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14736	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Reinhardt D (2002)	12381651	180579	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
15380	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Ito R (2006)	17034586	180845	1238	Olsalazine	Dipentum	dipentum	DRUGBANK	DB01250	C14H10N2O6	small molecule	A07EC03	15722-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QQBDLJCYGRGAKP-FOCLMDBBSA-N
15381	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Egan LJ (1998)	9797390	180846	1238	Olsalazine	Dipentum	dipentum	DRUGBANK	DB01250	C14H10N2O6	small molecule	A07EC03	15722-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QQBDLJCYGRGAKP-FOCLMDBBSA-N
15446	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Zhou H (2004)	14751502	180891	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15447	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Burris HA (2004)	15163842	180890	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15448	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Xia W (2004)	14737100	180889	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15449	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Vazquez-Martin A (2011)	20658522	180888	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15450	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Grana TM (2003)	14633707	180885	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15451	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Wood ER (2004)	15374980	180884	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15452	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Johnston SR (2006)	16894399	180887	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15453	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Xia W (2002)	12214266	180886	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15454	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Langer CJ (2004)	14967461	180881	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15455	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15456	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Tevaarwerk AJ (2010)	20110044	180883	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15457	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Medina PJ (2008)	18803986	180882	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15594	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Heymach JV (2006)	16857825	180948	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15595	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Cohen RB (2003)	12620146	180949	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15596	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Chen X (2002)	11752352	171740	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15597	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Foon KA (2004)	14967460	180947	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15598	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Keating GM (2010)	20481659	180957	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15599	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Yang XD (2001)	11255078	180956	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15600	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Segaert S (2005)	16012181	180955	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15601	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Lynch DH (2002)	11894013	180954	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15602	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Saadeh CE (2007)	17355997	180953	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15603	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Wu M (2008)	18343240	180952	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15604	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Jean GW (2008)	18503402	180951	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15605	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Keating GM (2010)	20623992	180950	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15606	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Ferrara N (2006)	17031284	180966	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15607	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gaudreault J (2007)	18046235	180967	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15608	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Kourlas H (2007)	18035187	180964	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15609	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Spitzer MS (2008)	19668384	180965	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15610	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Pieramici DJ (2006)	17049020	180962	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15611	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Nguyen QD (2006)	17046701	180963	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15612	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Michels S (2005)	15973626	180960	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15613	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Rosenfeld PJ (2006)	16935211	180961	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15614	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gaudreault J (2005)	15671306	180959	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15615	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Bakri SJ (2007)	18054637	180958	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15667	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Unknown Authors (2005)	15777106	181007	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15668	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Williams RM (2008)	18363546	181008	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15669	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Kemp SF (2009)	19627167	181009	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15731	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kalbag J (2004)	15177307	181038	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15732	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Tacconelli S (2004)	14965322	181037	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15733	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Atherton C (2004)	15017615	181036	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15734	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Esser R (2005)	15655513	181035	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15735	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Capone ML (2003)	14552704	181033	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15736	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1270	Lumiracoxib	COX189|Lumiracoxibum|2-((2-chloro-6-Fluorophenyl)amino)-5-methylbenzeneacetic acid|COX 189|Prexige|COX-189	-	DRUGBANK	DB01283	C15H13ClFNO2	small molecule	M01AH06	220991-20-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KHPKQFYUPIUARC-UHFFFAOYSA-N
15774	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Chen JT (2006)	16431966	181067	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15775	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Sarrazin S (2005)	16155294	181068	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15776	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Lortat-Jacob H (2006)	16709188	181069	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15777	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Chen JT (2006)	17238806	181070	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15778	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Fenton JI (2002)	12405690	181073	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15779	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Dodge GR (2003)	12801482	181072	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15780	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Chu SC (2006)	16756968	181071	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15781	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Mendis E (2006)	16616490	181075	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15782	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Rajapakse N (2007)	17498959	181074	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15783	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Lapaque N (2006)	16469053	181079	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15784	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Chen JT (2006)	16431966	181067	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15785	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Yi HA (2005)	16445576	181077	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15786	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Bitler CM (2005)	15930455	181076	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15787	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Delcommenne M (2002)	12244074	181078	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15788	110858	4791	-	NFKB2	CVID10|H2TF1|LYT-10|LYT10|NF-kB2|p100|p52	9606	Homo sapiens	antagonist	target	Largo R (2003)	12681956	181080	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
16414	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Graham GG (2004)	15035793	179201	1347	Magnesium salicylate	Magnesium salicylate anhydrous	diurex water pills|herbogesic|	DRUGBANK	DB01397	C14H10MgO6	small molecule	-	18917-89-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MQHWFIOJQSCFNM-UHFFFAOYSA-L
16415	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Elvira C (2001)	15348270	179208	1347	Magnesium salicylate	Magnesium salicylate anhydrous	diurex water pills|herbogesic|	DRUGBANK	DB01397	C14H10MgO6	small molecule	-	18917-89-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MQHWFIOJQSCFNM-UHFFFAOYSA-L
16416	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chae HJ (2004)	15106733	179207	1347	Magnesium salicylate	Magnesium salicylate anhydrous	diurex water pills|herbogesic|	DRUGBANK	DB01397	C14H10MgO6	small molecule	-	18917-89-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MQHWFIOJQSCFNM-UHFFFAOYSA-L
16417	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Fiebich BL (2004)	15070163	179206	1347	Magnesium salicylate	Magnesium salicylate anhydrous	diurex water pills|herbogesic|	DRUGBANK	DB01397	C14H10MgO6	small molecule	-	18917-89-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MQHWFIOJQSCFNM-UHFFFAOYSA-L
16418	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wu KK (2003)	15199473	179209	1347	Magnesium salicylate	Magnesium salicylate anhydrous	diurex water pills|herbogesic|	DRUGBANK	DB01397	C14H10MgO6	small molecule	-	18917-89-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MQHWFIOJQSCFNM-UHFFFAOYSA-L
16435	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Schaefer MG (2003)	12901032	181297	1349	Salsalate	Sasapyrin|Disalicylsaeure|Sasapyrinum|2-Carboxyphenyl salicylate|Salsalato|salicylsalicylic acid|Salicyloxysalicylic acid|O-Salicylsalicylic acid|Salsalatum|O-Salicylcylsalicylsaeure|Disalicylic acid|Sasapyrine|Salicylic acid bimolecular ester|Disalcid|Salicyloylsalicylic acid	salsalate|disalcid tab 750mg|d	DRUGBANK	DB01399	C14H10O5	small molecule	N02BA06	552-94-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WVYADZUPLLSGPU-UHFFFAOYSA-N
16436	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Motsko SP (2006)	16808554	181296	1349	Salsalate	Sasapyrin|Disalicylsaeure|Sasapyrinum|2-Carboxyphenyl salicylate|Salsalato|salicylsalicylic acid|Salicyloxysalicylic acid|O-Salicylsalicylic acid|Salsalatum|O-Salicylcylsalicylsaeure|Disalicylic acid|Sasapyrine|Salicylic acid bimolecular ester|Disalcid|Salicyloylsalicylic acid	salsalate|disalcid tab 750mg|d	DRUGBANK	DB01399	C14H10O5	small molecule	N02BA06	552-94-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WVYADZUPLLSGPU-UHFFFAOYSA-N
16437	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Stichtenoth DO (1998)	9711054	181295	1349	Salsalate	Sasapyrin|Disalicylsaeure|Sasapyrinum|2-Carboxyphenyl salicylate|Salsalato|salicylsalicylic acid|Salicyloxysalicylic acid|O-Salicylsalicylic acid|Salsalatum|O-Salicylcylsalicylsaeure|Disalicylic acid|Sasapyrine|Salicylic acid bimolecular ester|Disalcid|Salicyloylsalicylic acid	salsalate|disalcid tab 750mg|d	DRUGBANK	DB01399	C14H10O5	small molecule	N02BA06	552-94-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WVYADZUPLLSGPU-UHFFFAOYSA-N
16438	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Josephs MD (1999)	10452868	181294	1349	Salsalate	Sasapyrin|Disalicylsaeure|Sasapyrinum|2-Carboxyphenyl salicylate|Salsalato|salicylsalicylic acid|Salicyloxysalicylic acid|O-Salicylsalicylic acid|Salsalatum|O-Salicylcylsalicylsaeure|Disalicylic acid|Sasapyrine|Salicylic acid bimolecular ester|Disalcid|Salicyloylsalicylic acid	salsalate|disalcid tab 750mg|d	DRUGBANK	DB01399	C14H10O5	small molecule	N02BA06	552-94-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WVYADZUPLLSGPU-UHFFFAOYSA-N
16449	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Simon RA (2004)	14680616	181305	1351	Trisalicylate-choline	Tricosal	-	DRUGBANK	DB01401	C26H29MgNO10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQCQGOZEWWPOKI-UHFFFAOYSA-K
16450	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Shen J (2006)	17181859	179252	1351	Trisalicylate-choline	Tricosal	-	DRUGBANK	DB01401	C26H29MgNO10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQCQGOZEWWPOKI-UHFFFAOYSA-K
16451	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Nakano M (2007)	17258197	179253	1351	Trisalicylate-choline	Tricosal	-	DRUGBANK	DB01401	C26H29MgNO10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQCQGOZEWWPOKI-UHFFFAOYSA-K
16452	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Wang HJ (2006)	17037745	179254	1351	Trisalicylate-choline	Tricosal	-	DRUGBANK	DB01401	C26H29MgNO10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQCQGOZEWWPOKI-UHFFFAOYSA-K
16453	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Brzozowski T (2006)	17033106	179256	1351	Trisalicylate-choline	Tricosal	-	DRUGBANK	DB01401	C26H29MgNO10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQCQGOZEWWPOKI-UHFFFAOYSA-K
16489	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	Kim SJ (2007)	17436372	181309	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16490	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	Kim DH (2003)	14642426	181310	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16492	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kim SJ (2007)	17436372	181309	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16493	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yim HW (2005)	15753395	181312	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16494	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Seo JY (2005)	15778128	181313	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16507	112251	6347	-	CCL2	GDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF	9606	Homo sapiens	inhibitor	target	Boucher A (2000)	11056242	181321	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16508	112251	6347	-	CCL2	GDCF-2|HC11|HSMCR30|MCAF|MCP-1|MCP1|SCYA2|SMC-CF	9606	Homo sapiens	inhibitor	target	Jolicoeur C (2001)	11216879	181320	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16525	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Izeboud CA (1999)	10071758	181338	1356	Clenbuterol	4-amino-alpha-((Tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|()-clenbuterol|(+-)-Clenbuterol|1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol|4-amino-3,5-Dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol|CLENBUTEROL|4-amino--((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|Clenbuterolum	-	DRUGBANK	DB01407	C12H18Cl2N2O	small molecule	R03AC14|R03CC13	37148-27-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	STJMRWALKKWQGH-UHFFFAOYSA-N
16526	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Laan TT (2005)	16261833	181334	1356	Clenbuterol	4-amino-alpha-((Tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|()-clenbuterol|(+-)-Clenbuterol|1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol|4-amino-3,5-Dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol|CLENBUTEROL|4-amino--((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|Clenbuterolum	-	DRUGBANK	DB01407	C12H18Cl2N2O	small molecule	R03AC14|R03CC13	37148-27-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	STJMRWALKKWQGH-UHFFFAOYSA-N
16527	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Izeboud CA (2004)	15021963	181335	1356	Clenbuterol	4-amino-alpha-((Tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|()-clenbuterol|(+-)-Clenbuterol|1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol|4-amino-3,5-Dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol|CLENBUTEROL|4-amino--((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|Clenbuterolum	-	DRUGBANK	DB01407	C12H18Cl2N2O	small molecule	R03AC14|R03CC13	37148-27-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	STJMRWALKKWQGH-UHFFFAOYSA-N
16528	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	van den Hoven R (2006)	17139543	181336	1356	Clenbuterol	4-amino-alpha-((Tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|()-clenbuterol|(+-)-Clenbuterol|1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol|4-amino-3,5-Dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol|CLENBUTEROL|4-amino--((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|Clenbuterolum	-	DRUGBANK	DB01407	C12H18Cl2N2O	small molecule	R03AC14|R03CC13	37148-27-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	STJMRWALKKWQGH-UHFFFAOYSA-N
16529	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Yoshimura T (2000)	11193379	181337	1356	Clenbuterol	4-amino-alpha-((Tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|()-clenbuterol|(+-)-Clenbuterol|1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol|4-amino-3,5-Dichloro-alpha-(((1,1-dimethylethyl)amino)methyl)benzenemethanol|CLENBUTEROL|4-amino--((tert-butylamino)methyl)-3,5-dichlorobenzyl alcohol|Clenbuterolum	-	DRUGBANK	DB01407	C12H18Cl2N2O	small molecule	R03AC14|R03CC13	37148-27-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	STJMRWALKKWQGH-UHFFFAOYSA-N
16562	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	unknown	target	Ichiyama T (2003)	12801316	181363	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16563	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	unknown	target	Tomari S (2003)	12801315	181364	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16570	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Ichiyama T (2003)	12801316	181363	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16571	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Ichiyama T (2007)	17430359	181370	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16572	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Tomari S (2003)	12801315	181364	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16614	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Dhir A (2007)	17604186	178398	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16615	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	White WB (2007)	17612049	178399	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16616	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16617	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Hassan-Alin M (2007)	17532719	178402	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16618	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Kumar P (2007)	17521299	178400	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16619	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Albertini R (2007)	17607546	178401	1367	Antrafenine	-	-	DRUGBANK	DB01419	C30H26F6N4O2	small molecule	-	55300-29-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NWGGKKGAFZIVBJ-UHFFFAOYSA-N
16643	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Kumar A (1999)	10075051	181402	1375	Amrinone	Inamrinone|Amrinonum|Amcoral|Amrinona	inocor  liq 5mg/ml	DRUGBANK	DB01427	C10H9N3O	small molecule	C01CE01	60719-84-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RNLQIBCLLYYYFJ-UHFFFAOYSA-N
16644	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Haddad JJ (2002)	11805217	181403	1375	Amrinone	Inamrinone|Amrinonum|Amcoral|Amrinona	inocor  liq 5mg/ml	DRUGBANK	DB01427	C10H9N3O	small molecule	C01CE01	60719-84-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RNLQIBCLLYYYFJ-UHFFFAOYSA-N
16645	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Bergman MR (1999)	10444479	181400	1375	Amrinone	Inamrinone|Amrinonum|Amcoral|Amrinona	inocor  liq 5mg/ml	DRUGBANK	DB01427	C10H9N3O	small molecule	C01CE01	60719-84-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RNLQIBCLLYYYFJ-UHFFFAOYSA-N
16646	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Marx D (2002)	11969359	181401	1375	Amrinone	Inamrinone|Amrinonum|Amcoral|Amrinona	inocor  liq 5mg/ml	DRUGBANK	DB01427	C10H9N3O	small molecule	C01CE01	60719-84-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RNLQIBCLLYYYFJ-UHFFFAOYSA-N
16647	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Giroir BP (1992)	1611705	181399	1375	Amrinone	Inamrinone|Amrinonum|Amcoral|Amrinona	inocor  liq 5mg/ml	DRUGBANK	DB01427	C10H9N3O	small molecule	C01CE01	60719-84-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RNLQIBCLLYYYFJ-UHFFFAOYSA-N
16673	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Brune K (2001)	11695253	181415	1383	Antipyrine	1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one|Phenazone|Fenazon|2,3-Dimethyl-1-phenyl-5-pyrazolone|Fenazona|Antipyrine|Analgesine|Phenazon	auralgan eardrops|antipyrine a	DRUGBANK	DB01435	C11H12N2O	small molecule	S02DA03|N02BB51|N02BB71|N02BB01	60-80-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEQOALNAAJBPNY-UHFFFAOYSA-N
17203	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17204	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Rostaing L (2010)	20155724	181558	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17205	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	George S (2009)	19774211	181559	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17206	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Ettenger R (2008)	18466433	181554	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17207	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Coppin C (2010)	20531964	181555	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17208	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Albert S (2010)	20569080	181556	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17209	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Teachey DT (2009)	19344392	181557	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17311	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Brandt KD (1990)	2277128	181583	1538	Tiaprofenic acid	Tiaprofensaeure|Tiaprofensure|Acide tiaprofenique|5-Benzoyl-alpha-methyl-2-thiopheneacetic acid|5-Benzoyl-alpha-methylthiophene-2-acetic acid|2-(5-Benzyl-2-thienyl)propionsaeure|alpha-Methyl-5-benzoyl-2-thienylacetic acid|Acido tiaprofenico|Acidum tiaprofenicum|2-(5-Benzoyl-thiophen-2-yl)-propionic acid	surgam|tiaprofenic-200 - tab|a	DRUGBANK	DB01600	C14H12O3S	small molecule	M01AE11	33005-95-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GUHPRPJDBZHYCJ-UHFFFAOYSA-N
17312	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	1538	Tiaprofenic acid	Tiaprofensaeure|Tiaprofensure|Acide tiaprofenique|5-Benzoyl-alpha-methyl-2-thiopheneacetic acid|5-Benzoyl-alpha-methylthiophene-2-acetic acid|2-(5-Benzyl-2-thienyl)propionsaeure|alpha-Methyl-5-benzoyl-2-thienylacetic acid|Acido tiaprofenico|Acidum tiaprofenicum|2-(5-Benzoyl-thiophen-2-yl)-propionic acid	surgam|tiaprofenic-200 - tab|a	DRUGBANK	DB01600	C14H12O3S	small molecule	M01AE11	33005-95-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GUHPRPJDBZHYCJ-UHFFFAOYSA-N
17313	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1538	Tiaprofenic acid	Tiaprofensaeure|Tiaprofensure|Acide tiaprofenique|5-Benzoyl-alpha-methyl-2-thiopheneacetic acid|5-Benzoyl-alpha-methylthiophene-2-acetic acid|2-(5-Benzyl-2-thienyl)propionsaeure|alpha-Methyl-5-benzoyl-2-thienylacetic acid|Acido tiaprofenico|Acidum tiaprofenicum|2-(5-Benzoyl-thiophen-2-yl)-propionic acid	surgam|tiaprofenic-200 - tab|a	DRUGBANK	DB01600	C14H12O3S	small molecule	M01AE11	33005-95-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GUHPRPJDBZHYCJ-UHFFFAOYSA-N
17314	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	1538	Tiaprofenic acid	Tiaprofensaeure|Tiaprofensure|Acide tiaprofenique|5-Benzoyl-alpha-methyl-2-thiopheneacetic acid|5-Benzoyl-alpha-methylthiophene-2-acetic acid|2-(5-Benzyl-2-thienyl)propionsaeure|alpha-Methyl-5-benzoyl-2-thienylacetic acid|Acido tiaprofenico|Acidum tiaprofenicum|2-(5-Benzoyl-thiophen-2-yl)-propionic acid	surgam|tiaprofenic-200 - tab|a	DRUGBANK	DB01600	C14H12O3S	small molecule	M01AE11	33005-95-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GUHPRPJDBZHYCJ-UHFFFAOYSA-N
17449	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17450	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17451	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17452	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Yuan Y (2007)	17691997	181616	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17453	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Capone ML (2007)	17164136	181615	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17454	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	FitzGerald GA (2007)	17573128	181614	1565	Etoricoxib	5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine|5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine|Etoricoxibum|5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl|L791456|ETORICOXIB	-	DRUGBANK	DB01628	C18H15ClN2O2S	small molecule	M01AH05	202409-33-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNJVRJDLRVPLFE-UHFFFAOYSA-N
17457	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1567	SC-74020	-	-	DRUGBANK	DB01630	C29H42N4O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJNCFXPJICILOK-HHHXNRCGSA-N
17458	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1567	SC-74020	-	-	DRUGBANK	DB01630	C29H42N4O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJNCFXPJICILOK-HHHXNRCGSA-N
17705	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1684	Naphthalen-1-Yl-Acetic Acid	-	-	DRUGBANK	DB01750	C12H10O2	small molecule	-	86-87-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PRPINYUDVPFIRX-UHFFFAOYSA-N
17734	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17735	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17758	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17759	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17777	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1714	2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One	-	-	DRUGBANK	DB01782	C14H8N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACPOUJIDANTYHO-UHFFFAOYSA-N
17778	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1714	2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One	-	-	DRUGBANK	DB01782	C14H8N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACPOUJIDANTYHO-UHFFFAOYSA-N
17779	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1714	2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One	-	-	DRUGBANK	DB01782	C14H8N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACPOUJIDANTYHO-UHFFFAOYSA-N
17780	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1714	2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One	-	-	DRUGBANK	DB01782	C14H8N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACPOUJIDANTYHO-UHFFFAOYSA-N
17814	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17815	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17816	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
18009	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1805	N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide	-	-	DRUGBANK	DB01877	C13H19N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OJLWCTMBGWSVFC-JOYOIKCWSA-N
18010	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1805	N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide	-	-	DRUGBANK	DB01877	C13H19N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OJLWCTMBGWSVFC-JOYOIKCWSA-N
18011	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1808	3,4-Dihydroxycinnamic Acid	-	-	DRUGBANK	DB01880	C9H8O4	small molecule	-	331-39-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QAIPRVGONGVQAS-DUXPYHPUSA-N
18017	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18018	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18047	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1832	2-(2-Hydroxy-5-Methoxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine	-	-	DRUGBANK	DB01905	C15H15N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZFCKHJJALHETHG-UHFFFAOYSA-O
18139	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18140	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18141	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1873	2-Amino-N,3,3-Trimethylbutanamide	-	-	DRUGBANK	DB01949	C7H16N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPKJNEIOHOEWLO-RXMQYKEDSA-N
18142	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1873	2-Amino-N,3,3-Trimethylbutanamide	-	-	DRUGBANK	DB01949	C7H16N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPKJNEIOHOEWLO-RXMQYKEDSA-N
18147	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18148	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18230	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1901	6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB01977	C18H15N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AECPTICWHONWNW-UHFFFAOYSA-N
18231	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1901	6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB01977	C18H15N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AECPTICWHONWNW-UHFFFAOYSA-N
18232	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1901	6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB01977	C18H15N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AECPTICWHONWNW-UHFFFAOYSA-N
18241	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18242	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18259	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18260	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18261	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18282	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18283	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18284	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18285	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18334	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18335	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18336	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18337	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18390	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18391	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18392	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18404	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1971	2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide	-	-	DRUGBANK	DB02049	C19H20ClNO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QOPFTBAEAJQKSY-UHFFFAOYSA-N
18409	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18410	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18456	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18457	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18458	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18507	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2010	A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor	-	-	DRUGBANK	DB02090	C20H37N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLEGVELHGVWFGG-BBWFWOEESA-N
18508	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2010	A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor	-	-	DRUGBANK	DB02090	C20H37N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLEGVELHGVWFGG-BBWFWOEESA-N
18509	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2010	A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor	-	-	DRUGBANK	DB02090	C20H37N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLEGVELHGVWFGG-BBWFWOEESA-N
18510	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18511	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18512	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18513	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18568	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18569	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18575	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2037	CP-271485	2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl) ethyl-4-(4'-ethoxy [1,1'-biphenyl]-4-yl)-4-oxobutanoic acid|(6R)-4-BENZYL-6-(1-METHYL-2,2-DIOXIDO-1,3-DIHYDRO-2,1-BENZISOTHIAZOL-5-YL)MORPHOLIN-3-ONE	-	DRUGBANK	DB02118	C19H20N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIUMOGWIMXNXSQ-GOSISDBHSA-N
18576	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2037	CP-271485	2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl) ethyl-4-(4'-ethoxy [1,1'-biphenyl]-4-yl)-4-oxobutanoic acid|(6R)-4-BENZYL-6-(1-METHYL-2,2-DIOXIDO-1,3-DIHYDRO-2,1-BENZISOTHIAZOL-5-YL)MORPHOLIN-3-ONE	-	DRUGBANK	DB02118	C19H20N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIUMOGWIMXNXSQ-GOSISDBHSA-N
18577	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2037	CP-271485	2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl) ethyl-4-(4'-ethoxy [1,1'-biphenyl]-4-yl)-4-oxobutanoic acid|(6R)-4-BENZYL-6-(1-METHYL-2,2-DIOXIDO-1,3-DIHYDRO-2,1-BENZISOTHIAZOL-5-YL)MORPHOLIN-3-ONE	-	DRUGBANK	DB02118	C19H20N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIUMOGWIMXNXSQ-GOSISDBHSA-N
18621	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2069	K-252a	-	-	DRUGBANK	DB02152	C27H21N3O5	small molecule	-	97161-97-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KOZFSFOOLUUIGY-SOLYNIJKSA-N
18695	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2109	2-(2-Hydroxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine	-	-	DRUGBANK	DB02193	C14H13N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDVCRKGBQLPJRQ-ZROIWOOFSA-O
18697	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18698	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18699	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18713	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18714	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18715	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18734	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18735	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18736	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18832	109330	3082	-	HGF	DFNB39|F-TCF|HGFB|HPTA|SF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2173	O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB02264	C6H10O10S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	COJBCAMFZDFGFK-SZXBDDMQSA-N
18833	109330	3082	-	HGF	DFNB39|F-TCF|HGFB|HPTA|SF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2173	O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB02264	C6H10O10S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	COJBCAMFZDFGFK-SZXBDDMQSA-N
18842	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Ouellet M (1995)	7864817	181626	2175	Flufenamic Acid	-	-	DRUGBANK	DB02266	C14H10F3NO2	small molecule	M01AG03	530-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LPEPZBJOKDYZAD-UHFFFAOYSA-N
18864	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18865	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18866	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18889	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
18890	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
18946	112255	6352	-	CCL5	D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2229	Heparin Disaccharide I-S	-	-	DRUGBANK	DB02322	C12H15NO19S3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LRPGJWKAYQRIAQ-XKUCOZAXSA-J
18947	112255	6352	-	CCL5	D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2229	Heparin Disaccharide I-S	-	-	DRUGBANK	DB02322	C12H15NO19S3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LRPGJWKAYQRIAQ-XKUCOZAXSA-J
19008	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2255	N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide	-	-	DRUGBANK	DB02350	C15H22N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYYCSKFJEOSZTF-CYBMUJFWSA-N
19009	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2255	N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide	-	-	DRUGBANK	DB02350	C15H22N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYYCSKFJEOSZTF-CYBMUJFWSA-N
19010	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2255	N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide	-	-	DRUGBANK	DB02350	C15H22N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYYCSKFJEOSZTF-CYBMUJFWSA-N
19012	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19013	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19014	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19016	112255	6352	-	CCL5	D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2258	Heparin Disaccharide Iii-S	-	-	DRUGBANK	DB02353	C12H16NO16S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSYQGRODWXMUOO-XKUCOZAXSA-K
19017	112255	6352	-	CCL5	D17S136E|RANTES|SCYA5|SIS-delta|SISd|TCP228|eoCP	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2258	Heparin Disaccharide Iii-S	-	-	DRUGBANK	DB02353	C12H16NO16S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSYQGRODWXMUOO-XKUCOZAXSA-K
19037	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2272	(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine	-	-	DRUGBANK	DB02367	C16H25N3O7S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ULDXUWXTVRRUND-SWLSCSKDSA-N
19038	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2272	(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine	-	-	DRUGBANK	DB02367	C16H25N3O7S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ULDXUWXTVRRUND-SWLSCSKDSA-N
19097	109678	3456	RP11-113D19.1	IFNB1	IFB|IFF|IFNB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2284	Beta-D-Glucose	Glucose, beta-D-|Glucoside|beta-D-glucopyranose|Beta-D-glucose, anhydrous|Glucose, beta-D|Beta-D-glucose anhydrous	-	DRUGBANK	DB02379	C6H12O6	small molecule	-	492-61-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZGKKKJIJFFOK-VFUOTHLCSA-N
19098	109678	3456	RP11-113D19.1	IFNB1	IFB|IFF|IFNB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2284	Beta-D-Glucose	Glucose, beta-D-|Glucoside|beta-D-glucopyranose|Beta-D-glucose, anhydrous|Glucose, beta-D|Beta-D-glucose anhydrous	-	DRUGBANK	DB02379	C6H12O6	small molecule	-	492-61-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZGKKKJIJFFOK-VFUOTHLCSA-N
19128	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2293	Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine	-	-	DRUGBANK	DB02388	C27H34Cl2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQFRSHRWRKYNDE-UHFFFAOYSA-N
19129	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2293	Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine	-	-	DRUGBANK	DB02388	C27H34Cl2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQFRSHRWRKYNDE-UHFFFAOYSA-N
19141	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2301	6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02398	C19H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLBDETRVUYOIHQ-UHFFFAOYSA-N
19142	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2301	6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02398	C19H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLBDETRVUYOIHQ-UHFFFAOYSA-N
19143	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2301	6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02398	C19H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLBDETRVUYOIHQ-UHFFFAOYSA-N
19154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19157	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19225	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2350	3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid	-	-	DRUGBANK	DB02449	C28H28N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUWISPSREJFEEW-HHHXNRCGSA-N
19226	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2350	3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid	-	-	DRUGBANK	DB02449	C28H28N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PUWISPSREJFEEW-HHHXNRCGSA-N
19272	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2373	6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02473	C24H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRHANBWAKSYPEN-UHFFFAOYSA-N
19273	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2373	6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02473	C24H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRHANBWAKSYPEN-UHFFFAOYSA-N
19274	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2373	6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02473	C24H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRHANBWAKSYPEN-UHFFFAOYSA-N
19284	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19285	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19286	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19394	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2423	CRA_10655	-	-	DRUGBANK	DB02526	C19H20N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCFWDBPDMBXMTQ-UHFFFAOYSA-N
19418	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19419	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19420	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19445	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2448	6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02551	C23H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNMYQLXKMSQTG-AWEZNQCLSA-N
19446	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2448	6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02551	C23H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNMYQLXKMSQTG-AWEZNQCLSA-N
19447	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2448	6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02551	C23H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNMYQLXKMSQTG-AWEZNQCLSA-N
19526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19527	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19528	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19620	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19621	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19622	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19723	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19724	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19725	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19726	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19738	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2594	6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02705	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DARQQJKHXPXSRO-QFIPXVFZSA-N
19739	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2594	6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02705	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DARQQJKHXPXSRO-QFIPXVFZSA-N
19740	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2594	6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine	-	-	DRUGBANK	DB02705	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DARQQJKHXPXSRO-QFIPXVFZSA-N
19745	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2597	Resveratrol	(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol|trans-3,4',5-trihydroxystilbene|(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol|3,4',5-Stilbenetriol|3,4',5-Trihydroxystilbene|(E)-5-(p-Hydroxystyryl)resorcinol|3,4',5-trihydroxy-stilbene|(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol|(E)-resveratrol	co-veratrol	DRUGBANK	DB02709	C14H12O3	small molecule	-	501-36-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUKBXSAWLPMMSZ-OWOJBTEDSA-N
19805	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2616	7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester	-	-	DRUGBANK	DB02728	C12H10O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IETDBZQIWIJQJG-UHFFFAOYSA-N
19806	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2616	7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester	-	-	DRUGBANK	DB02728	C12H10O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IETDBZQIWIJQJG-UHFFFAOYSA-N
19807	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2616	7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester	-	-	DRUGBANK	DB02728	C12H10O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IETDBZQIWIJQJG-UHFFFAOYSA-N
19812	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19814	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19815	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19816	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19817	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19818	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19986	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19987	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19988	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19989	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
20059	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2754	Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone	-	-	DRUGBANK	DB02872	C31H34Br2N4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVRYEWOXWGDQHA-FQLXRVMXSA-N
20060	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2754	Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone	-	-	DRUGBANK	DB02872	C31H34Br2N4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVRYEWOXWGDQHA-FQLXRVMXSA-N
20061	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20062	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20063	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20095	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20096	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20127	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20128	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20129	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20130	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20185	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20200	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20201	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20202	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20216	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20217	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20233	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20234	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20235	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20323	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20324	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20357	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20358	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20359	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20360	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20375	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20376	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20377	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2918	7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB03046	C16H16N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KQUXAFOLFXHVQN-UHFFFAOYSA-N
20378	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2918	7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB03046	C16H16N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KQUXAFOLFXHVQN-UHFFFAOYSA-N
20379	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2918	7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB03046	C16H16N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KQUXAFOLFXHVQN-UHFFFAOYSA-N
20436	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2953	6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide	-	-	DRUGBANK	DB03082	C23H21N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CSWQJKHBMACTGB-UHFFFAOYSA-N
20437	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2953	6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide	-	-	DRUGBANK	DB03082	C23H21N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CSWQJKHBMACTGB-UHFFFAOYSA-N
20439	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2955	Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine	-	-	DRUGBANK	DB03084	C25H30Cl2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCTKFTOEAKJMII-UHFFFAOYSA-N
20440	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2955	Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine	-	-	DRUGBANK	DB03084	C25H30Cl2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCTKFTOEAKJMII-UHFFFAOYSA-N
20456	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20457	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20458	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20462	106780	283	-	ANG	ALS9|HEL168|RAA1|RNASE4|RNASE5	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20463	106780	283	-	ANG	ALS9|HEL168|RAA1|RNASE4|RNASE5	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20505	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20506	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20510	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2986	5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide	-	-	DRUGBANK	DB03115	C16H13BrF3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSSGBYXSKOLAM-MRVPVSSYSA-N
20511	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2986	5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide	-	-	DRUGBANK	DB03115	C16H13BrF3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSSGBYXSKOLAM-MRVPVSSYSA-N
20548	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2996	Benzamidine	-	-	DRUGBANK	DB03127	C7H9N2	small molecule	-	618-39-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PXXJHWLDUBFPOL-UHFFFAOYSA-O
20549	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2996	Benzamidine	-	-	DRUGBANK	DB03127	C7H9N2	small molecule	-	618-39-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PXXJHWLDUBFPOL-UHFFFAOYSA-O
20569	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3004	4-Iodobenzo[B]Thiophene-2-Carboxamidine	-	-	DRUGBANK	DB03136	C9H8IN2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YERQOXAYAFWFEJ-UHFFFAOYSA-O
20694	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3027	CRA_8696	-	-	DRUGBANK	DB03159	C21H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GAVRMVQHHVMXFD-UHFFFAOYSA-N
20786	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20787	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20788	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20918	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3162	Benzylsulfinic Acid	-	-	DRUGBANK	DB03297	C7H8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVSONFIVLCXXDH-UHFFFAOYSA-N
20919	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3162	Benzylsulfinic Acid	-	-	DRUGBANK	DB03297	C7H8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVSONFIVLCXXDH-UHFFFAOYSA-N
20920	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3162	Benzylsulfinic Acid	-	-	DRUGBANK	DB03297	C7H8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVSONFIVLCXXDH-UHFFFAOYSA-N
20933	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20934	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20935	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20959	115915	10673	RP11-153I24.1	TNFSF13B	BAFF|BLYS|CD257|DTL|TALL-1|TALL1|THANK|TNFSF20|ZTNF4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3181	1,4-Diethylene Dioxide	-	-	DRUGBANK	DB03316	C4H8O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYHBNJHYFVUHQT-UHFFFAOYSA-N
20960	115915	10673	RP11-153I24.1	TNFSF13B	BAFF|BLYS|CD257|DTL|TALL-1|TALL1|THANK|TNFSF20|ZTNF4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3181	1,4-Diethylene Dioxide	-	-	DRUGBANK	DB03316	C4H8O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYHBNJHYFVUHQT-UHFFFAOYSA-N
21009	116609	22955	-	SCMH1	Scml3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3208	Beta-Mercaptoethanol	2-Sulfhydryl-Ethanol	-	DRUGBANK	DB03345	C2H6OS	small molecule	-	60-24-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGVVWUTYPXICAM-UHFFFAOYSA-N
21040	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21041	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21042	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21043	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3228	PF-00356231	3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid	-	DRUGBANK	DB03367	C25H20N2O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMTJQZUZINLEKC-JOCHJYFZSA-N
21044	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3228	PF-00356231	3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid	-	DRUGBANK	DB03367	C25H20N2O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMTJQZUZINLEKC-JOCHJYFZSA-N
21045	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3228	PF-00356231	3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thien-2-yl]carbonyl}amino)propanoic acid	-	DRUGBANK	DB03367	C25H20N2O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMTJQZUZINLEKC-JOCHJYFZSA-N
21046	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3229	5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione	-	-	DRUGBANK	DB03368	C17H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTBMLCLTYAPKIF-UHFFFAOYSA-N
21047	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3229	5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione	-	-	DRUGBANK	DB03368	C17H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTBMLCLTYAPKIF-UHFFFAOYSA-N
21048	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3229	5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione	-	-	DRUGBANK	DB03368	C17H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTBMLCLTYAPKIF-UHFFFAOYSA-N
21186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21189	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21353	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3331	Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine	-	-	DRUGBANK	DB03476	C20H18N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NQRIWXVAIWPBEM-OALUTQOASA-N
21354	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3331	Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine	-	-	DRUGBANK	DB03476	C20H18N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NQRIWXVAIWPBEM-OALUTQOASA-N
21355	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3331	Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine	-	-	DRUGBANK	DB03476	C20H18N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NQRIWXVAIWPBEM-OALUTQOASA-N
21356	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3332	1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole	-	-	DRUGBANK	DB03477	C16H11BrF3N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYZKFVIVPRQRQQ-UHFFFAOYSA-N
21384	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21385	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21386	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21393	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21394	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21398	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21400	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21401	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Zvelebil MJ (1998)	18465538	182075	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21419	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21420	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21421	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21535	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21536	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21537	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21610	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3470	9-(4-Hydroxyphenyl)-2,7-Phenanthroline	-	-	DRUGBANK	DB03623	C18H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IUSSGTWHFMSCOY-UHFFFAOYSA-N
21611	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3470	9-(4-Hydroxyphenyl)-2,7-Phenanthroline	-	-	DRUGBANK	DB03623	C18H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IUSSGTWHFMSCOY-UHFFFAOYSA-N
21612	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3470	9-(4-Hydroxyphenyl)-2,7-Phenanthroline	-	-	DRUGBANK	DB03623	C18H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IUSSGTWHFMSCOY-UHFFFAOYSA-N
21632	111469	5473	-	PPBP	B-TG1|Beta-TG|CTAP-III|CTAP3|CTAPIII|CXCL7|LA-PF4|LDGF|MDGF|NAP-2|PBP|SCYB7|TC1|TC2|TGB|TGB1|THBGB|THBGB1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3482	Ethanesulfonic Acid	-	-	DRUGBANK	DB03635	C2H6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCIVGXIOQKPBKL-UHFFFAOYSA-N
21633	111469	5473	-	PPBP	B-TG1|Beta-TG|CTAP-III|CTAP3|CTAPIII|CXCL7|LA-PF4|LDGF|MDGF|NAP-2|PBP|SCYB7|TC1|TC2|TGB|TGB1|THBGB|THBGB1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3482	Ethanesulfonic Acid	-	-	DRUGBANK	DB03635	C2H6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCIVGXIOQKPBKL-UHFFFAOYSA-N
21674	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21675	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21676	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21706	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21707	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21708	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21810	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3572	2-Amino-5-Hydroxy-Benzimidazole	-	-	DRUGBANK	DB03729	C7H6N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
21811	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3572	2-Amino-5-Hydroxy-Benzimidazole	-	-	DRUGBANK	DB03729	C7H6N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
21826	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21827	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21828	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21863	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21864	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21865	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21917	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3622	N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea	-	-	DRUGBANK	DB03782	C19H27N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQPLKJCBEOVDBS-CSVIQDERSA-N
21918	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3622	N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea	-	-	DRUGBANK	DB03782	C19H27N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQPLKJCBEOVDBS-CSVIQDERSA-N
21919	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3622	N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea	-	-	DRUGBANK	DB03782	C19H27N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQPLKJCBEOVDBS-CSVIQDERSA-N
21979	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
21980	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
22087	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3702	6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine	-	-	DRUGBANK	DB03865	C21H17ClN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FEKRWNWZMOSVBX-UHFFFAOYSA-O
22090	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3703	Prostaglandin G2	-	-	DRUGBANK	DB03866	C20H32O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SGUKUZOVHSFKPH-YNNPMVKQSA-N
22094	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3713	Thieno[2,3-B]Pyridine-2-Carboxamidine	-	-	DRUGBANK	DB03876	C8H8N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZEJMYFXZMUAEC-UHFFFAOYSA-O
22105	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3717	Batimastat	-	-	DRUGBANK	DB03880	C23H31N3O4S2	small molecule	-	130370-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFILPEOLDIKJHX-QYZOEREBSA-N
22106	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3717	Batimastat	-	-	DRUGBANK	DB03880	C23H31N3O4S2	small molecule	-	130370-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFILPEOLDIKJHX-QYZOEREBSA-N
22107	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3717	Batimastat	-	-	DRUGBANK	DB03880	C23H31N3O4S2	small molecule	-	130370-60-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFILPEOLDIKJHX-QYZOEREBSA-N
22217	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3771	1,4-Dideoxy-O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB03935	C6H10O8S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IRTONBQROPNEJZ-UOWFLXDJSA-N
22218	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3771	1,4-Dideoxy-O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB03935	C6H10O8S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IRTONBQROPNEJZ-UOWFLXDJSA-N
22273	109330	3082	-	HGF	DFNB39|F-TCF|HGFB|HPTA|SF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3794	N,O6-Disulfo-Glucosamine	-	-	DRUGBANK	DB03959	C6H13NO11S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQTRACMFIGDHSN-RUTHBDMASA-N
22274	109330	3082	-	HGF	DFNB39|F-TCF|HGFB|HPTA|SF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3794	N,O6-Disulfo-Glucosamine	-	-	DRUGBANK	DB03959	C6H13NO11S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQTRACMFIGDHSN-RUTHBDMASA-N
22277	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3794	N,O6-Disulfo-Glucosamine	-	-	DRUGBANK	DB03959	C6H13NO11S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQTRACMFIGDHSN-RUTHBDMASA-N
22278	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3794	N,O6-Disulfo-Glucosamine	-	-	DRUGBANK	DB03959	C6H13NO11S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQTRACMFIGDHSN-RUTHBDMASA-N
22288	112952	7097	-	TLR2	CD282|TIL4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3798	S-(Dimethylarsenic)Cysteine	-	-	DRUGBANK	DB03963	C5H12AsNO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UKLXSOVDMSQHMM-SCSAIBSYSA-N
22289	112952	7097	-	TLR2	CD282|TIL4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3798	S-(Dimethylarsenic)Cysteine	-	-	DRUGBANK	DB03963	C5H12AsNO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UKLXSOVDMSQHMM-SCSAIBSYSA-N
22329	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3814	4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole	-	-	DRUGBANK	DB03980	C17H16FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFEYXQGDDCDXJK-UHFFFAOYSA-N
22333	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3815	1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB03981	C6H8O8S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLBOXLMLDIGNGG-NQXXGFSBSA-N
22334	108538	2247	-	FGF2	BFGF|FGF-2|FGFB|HBGF-2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3815	1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid	-	-	DRUGBANK	DB03981	C6H8O8S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLBOXLMLDIGNGG-NQXXGFSBSA-N
22373	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22374	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22375	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22446	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3891	8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB04059	C15H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GRQLDCHTDNYVQI-UHFFFAOYSA-N
22447	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3891	8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB04059	C15H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GRQLDCHTDNYVQI-UHFFFAOYSA-N
22448	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3891	8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide	-	-	DRUGBANK	DB04059	C15H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GRQLDCHTDNYVQI-UHFFFAOYSA-N
22570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22644	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22645	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22646	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22663	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3971	1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide	-	-	DRUGBANK	DB04140	C19H21N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUSMVCKSLVPRCL-QGZVFWFLSA-N
22664	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3971	1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide	-	-	DRUGBANK	DB04140	C19H21N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUSMVCKSLVPRCL-QGZVFWFLSA-N
22665	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3971	1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide	-	-	DRUGBANK	DB04140	C19H21N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUSMVCKSLVPRCL-QGZVFWFLSA-N
22685	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22686	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22687	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3975	Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone	-	-	DRUGBANK	DB04144	C30H32Cl2N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXIPEZDMQNYFOO-VSGBNLITSA-N
22761	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4002	[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine	-	-	DRUGBANK	DB04172	C32H48N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WATXEHGLYJKXOF-MUUNZHRXSA-N
22762	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4002	[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine	-	-	DRUGBANK	DB04172	C32H48N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WATXEHGLYJKXOF-MUUNZHRXSA-N
22781	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22782	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22783	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22849	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4060	N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide	-	-	DRUGBANK	DB04232	C20H23N3O7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNGGPLKVDUPXFN-GOSISDBHSA-N
22850	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4060	N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide	-	-	DRUGBANK	DB04232	C20H23N3O7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNGGPLKVDUPXFN-GOSISDBHSA-N
22851	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4060	N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide	-	-	DRUGBANK	DB04232	C20H23N3O7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNGGPLKVDUPXFN-GOSISDBHSA-N
22950	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22951	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22957	106780	283	-	ANG	ALS9|HEL168|RAA1|RNASE4|RNASE5	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22958	106780	283	-	ANG	ALS9|HEL168|RAA1|RNASE4|RNASE5	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22964	115915	10673	RP11-153I24.1	TNFSF13B	BAFF|BLYS|CD257|DTL|TALL-1|TALL1|THANK|TNFSF20|ZTNF4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22965	115915	10673	RP11-153I24.1	TNFSF13B	BAFF|BLYS|CD257|DTL|TALL-1|TALL1|THANK|TNFSF20|ZTNF4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
23004	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23005	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23006	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23055	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23056	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23057	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23162	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23163	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23164	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23318	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23319	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23348	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4223	2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid	-	-	DRUGBANK	DB04405	C28H25NO6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AQYSXARQCHHHLK-OAQYLSRUSA-N
23349	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4223	2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid	-	-	DRUGBANK	DB04405	C28H25NO6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AQYSXARQCHHHLK-OAQYLSRUSA-N
23350	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23351	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23352	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23362	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4232	R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid	-	-	DRUGBANK	DB04416	C20H21NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QJKGJGURDPRKGW-LJQANCHMSA-N
23363	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4232	R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid	-	-	DRUGBANK	DB04416	C20H21NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QJKGJGURDPRKGW-LJQANCHMSA-N
23364	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4232	R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid	-	-	DRUGBANK	DB04416	C20H21NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QJKGJGURDPRKGW-LJQANCHMSA-N
23386	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4251	3-Fluorotyrosine	3-fluoro-L-tyrosine	-	DRUGBANK	DB04436	C9H10FNO3	small molecule	-	403-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VIIAUOZUUGXERI-ZETCQYMHSA-N
23387	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4251	3-Fluorotyrosine	3-fluoro-L-tyrosine	-	DRUGBANK	DB04436	C9H10FNO3	small molecule	-	403-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VIIAUOZUUGXERI-ZETCQYMHSA-N
23388	112531	6648	RP1-56L9.2	SOD2	IPOB|MNSOD|MVCD6	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4251	3-Fluorotyrosine	3-fluoro-L-tyrosine	-	DRUGBANK	DB04436	C9H10FNO3	small molecule	-	403-90-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VIIAUOZUUGXERI-ZETCQYMHSA-N
23545	109839	3627	-	CXCL10	C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4300	N-Methylleucine	-	-	DRUGBANK	DB04487	C7H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJODGRWDFZVTKW-ZCFIWIBFSA-N
23546	109839	3627	-	CXCL10	C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4300	N-Methylleucine	-	-	DRUGBANK	DB04487	C7H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJODGRWDFZVTKW-ZCFIWIBFSA-N
23592	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23593	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23594	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23687	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Alpert E (2007)	17098211	138173	4362	Niflumic Acid	Acidum niflumicum|Acide niflumique|Niflugel|NFA|Acido niflumico	-	DRUGBANK	DB04552	C13H9F3N2O2	small molecule	M02AA17|M01AX02	4394-00-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZFPYUNJRRFVQU-UHFFFAOYSA-N
23688	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Jabeen T (2005)	16301791	181921	4362	Niflumic Acid	Acidum niflumicum|Acide niflumique|Niflugel|NFA|Acido niflumico	-	DRUGBANK	DB04552	C13H9F3N2O2	small molecule	M02AA17|M01AX02	4394-00-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZFPYUNJRRFVQU-UHFFFAOYSA-N
23689	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Diao HL (2007)	17485303	182008	4362	Niflumic Acid	Acidum niflumicum|Acide niflumique|Niflugel|NFA|Acido niflumico	-	DRUGBANK	DB04552	C13H9F3N2O2	small molecule	M02AA17|M01AX02	4394-00-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZFPYUNJRRFVQU-UHFFFAOYSA-N
23766	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4413	5-iodotubercidin	-	-	DRUGBANK	DB04604	C11H13IN4O4	small molecule	-	24386-93-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHSIXKUPQCKWBY-IOSLPCCCSA-N
23767	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4416	PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE	-	-	DRUGBANK	DB04607	C20H14Cl2N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQAWGIKJINAKIZ-UHFFFAOYSA-N
23786	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4438	4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE	-	-	DRUGBANK	DB04632	C24H26FN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JHHBGNIRSUTQAS-UHFFFAOYSA-N
23804	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4467	OLOMOUCINE II	-	-	DRUGBANK	DB04662	C19H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NDUVSANREQEDRE-CQSZACIVSA-N
23806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4474	TRIAZOLOPYRIMIDINE	-	-	DRUGBANK	DB04669	C17H14BrN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWBFPKPWMSWWEA-UHFFFAOYSA-O
23849	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Vidal C (2007)	17015640	181969	4529	Licofelone	LCF|ML3000	-	DRUGBANK	DB04725	C23H22ClNO2	small molecule	-	156897-06-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UAWXGRJVZSAUSZ-UHFFFAOYSA-N
23862	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Rainsford KD (2006)	16846549	181954	4546	Nimesulide	-	-	DRUGBANK	DB04743	C13H12N2O5S	small molecule	M01AX17|M02AA26	51803-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYWYRSMBCFDLJT-UHFFFAOYSA-N
23863	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	4546	Nimesulide	-	-	DRUGBANK	DB04743	C13H12N2O5S	small molecule	M01AX17|M02AA26	51803-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYWYRSMBCFDLJT-UHFFFAOYSA-N
23866	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4554	Purvalanol A	6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine|Purv	-	DRUGBANK	DB04751	C19H25ClN6O	small molecule	-	212844-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PMXCMJLOPOFPBT-HNNXBMFYSA-N
23870	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4562	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE)	-	-	DRUGBANK	DB04759	C22H22N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTBUZLPQANSGGE-UHFFFAOYSA-N
23871	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4563	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE)	-	-	DRUGBANK	DB04760	C22H20F2N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYFRREJCFXFNRR-UHFFFAOYSA-N
23872	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4564	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE]	-	-	DRUGBANK	DB04761	C18H16N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHPBWKYFMTXWAA-UHFFFAOYSA-N
23910	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4599	Triazolopyridine	-	-	DRUGBANK	DB04797	C18H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVCXRBARSPBVMC-UHFFFAOYSA-N
24039	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Elkin M (2000)	11099465	181766	4666	Halofuginone	Tempostatin (Collgard Biopharmaceuticals)	-	DRUGBANK	DB04866	C16H17BrClN3O3	small molecule	-	55837-20-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVASCWIMLIKXLA-YSSOQSIOSA-N
24179	112874	7015	-	TERT	CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT	9606	Homo sapiens	unknown	target	Kokhaei P (2007)	17258078	181984	4733	GV1001	-	-	DRUGBANK	DB04937	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24232	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Vincent JL (2000)	10829362	181750	4750	Afelimomab	MAK 195F|Fab 2	-	DRUGBANK	DB04956	-	biologic	L04AB03	156227-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24279	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Farhan H (2006)	16963623	181966	4779	IGN311	-	-	DRUGBANK	DB04988	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24286	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	Almansa C (2004)	15481993	181866	4878	Cimicoxib	-	-	DRUGBANK	DB05095	C16H13ClFN3O3S	small molecule	-	265114-23-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KYXDNECMRLFQMZ-UHFFFAOYSA-N
24303	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	antagonist	target	Eby G (2005)	16122880	181906	5038	Gallium nitrate	Gallium nitrate (anhydrous)|Nitric acid, gallium salt, anhydrate	ganite	DRUGBANK	DB05260	GaN3O9	small molecule	-	13494-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CHPZKNULDCNCBW-UHFFFAOYSA-N
24359	109790	3576	-	CXCL8	GCP-1|GCP1|IL8|LECT|LUCT|LYNAP|MDNCF|MONAP|NAF|NAP-1|NAP1	9606	Homo sapiens	antagonist	target	Spoettl T (2007)	16715250	181946	5414	Rivanicline	(3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine|(E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine|(E)-metanicotine|N-methyl-4-(3-pyridinyl)-(3E)-3-buten-1-amine|trans-metanicotine	-	DRUGBANK	DB05855	C10H14N2	small molecule	-	15585-43-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JUOSGGQXEBBCJB-GORDUTHDSA-N
24404	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Oka S (2000)	10788610	181749	5519	Acetylcysteine	(R)-Mercapturic acid|N-acetylcysteine|N-Acetyl-L-(+)-cysteine|(2R)-2-acetylamino-3-Sulfanylpropanoic acid|Acetilcisteina|Mercapturic acid|Acetylcysteine|Acetylcysteinum|L-Acetylcysteine|(R)-2-acetylamino-3-Mercaptopropanoic acid|N-ACETYL-L-cysteine|L-alpha-acetamido-beta-Mercaptopropionic acid	parvolex|parvolex liq iv 200mg	DRUGBANK	DB06151	C5H9NO3S	small molecule	V03AB23|S01XA08|R05CB01	616-91-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWKSKIMOESPYIA-BYPYZUCNSA-N
24407	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Church LD (2009)	19169963	182096	5521	Canakinumab	ACZ-885|ACZ885	ilaris	DRUGBANK	DB06168	C6452H9958N1722O2010S42	biologic	L04AC08	914613-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24548	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24549	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Radulovic S (2007)	17935273	182057	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24550	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Patard JJ (2008)	18265991	182064	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24563	109768	3552	-	IL1A	IL-1A|IL1|IL1-ALPHA|IL1F1	9606	Homo sapiens	binder	target	Tran TH (2013)	23553601	182241	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24564	109768	3552	-	IL1A	IL-1A|IL1|IL1-ALPHA|IL1F1	9606	Homo sapiens	binder	target	Cronstein BN (2013)	23319019	182226	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24567	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Tran TH (2013)	23553601	182241	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24568	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Cronstein BN (2013)	23319019	182226	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24591	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24624	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	antibody	target	Mittal M (2010)	21079302	182177	5569	Golimumab	-	simponi aria|simponi i.v.|simp	DRUGBANK	DB06674	C6530H10068N1752O2026S44	biologic	L04AB06	476181-74-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24785	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Renner RM (2010)	20399943	182151	5605	Lornoxicam	Chlortenoxicam|Lornoxicamum	-	DRUGBANK	DB06725	C13H10ClN3O4S2	small molecule	M01AC05	70374-39-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WLHQHAUOOXYABV-UHFFFAOYSA-N
24786	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Rose P (2007)	17516707	182014	5605	Lornoxicam	Chlortenoxicam|Lornoxicamum	-	DRUGBANK	DB06725	C13H10ClN3O4S2	small molecule	M01AC05	70374-39-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WLHQHAUOOXYABV-UHFFFAOYSA-N
24787	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Berg J (1999)	10450786	181738	5605	Lornoxicam	Chlortenoxicam|Lornoxicamum	-	DRUGBANK	DB06725	C13H10ClN3O4S2	small molecule	M01AC05	70374-39-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WLHQHAUOOXYABV-UHFFFAOYSA-N
24788	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Bianchi M (2002)	11846620	181788	5605	Lornoxicam	Chlortenoxicam|Lornoxicamum	-	DRUGBANK	DB06725	C13H10ClN3O4S2	small molecule	M01AC05	70374-39-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WLHQHAUOOXYABV-UHFFFAOYSA-N
24824	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Norrby K (2010)	21091776	182178	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24825	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Marchetti M (2007)	17692905	182038	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24826	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Takahashi H (2005)	16041398	181901	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24839	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Gamache DA (2000)	10850857	181753	5639	Nepafenac	AHR 9434|Amfenac amide|AL-6515|Nepafenaco|2-amino-3-Benzoylbenzeneacetamide|AL 6515|Nepafenacum|AHR-9434|Nevanac	ilevro|nevanac	DRUGBANK	DB06802	C15H14N2O2	small molecule	S01BC10	78281-72-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QEFAQIPZVLVERP-UHFFFAOYSA-N
24844	112288	6387	-	CXCL12	IRH|PBSF|SCYB12|SDF1|TLSF|TPAR1	9606	Homo sapiens	binder	target	Koo CY (2008)	18991783	182089	5647	Tinzaparin	Tinzaparin sodium	innohep multi-dose vial- 10000	DRUGBANK	DB06822	-	small molecule	B01AB10	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24870	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5665	4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE	-	-	DRUGBANK	DB06844	C21H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBXKBJLIESPLIK-UHFFFAOYSA-N
24871	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5665	4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE	-	-	DRUGBANK	DB06844	C21H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBXKBJLIESPLIK-UHFFFAOYSA-N
24880	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5673	4-[(3S)-1-AZABICYCLO[2.2.2]OCT-3-YLAMINO]-3-(1H-BENZIMIDAZOL-2-YL)-6-CHLOROQUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB06852	C23H22ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOVBBVMDHIRCTG-LJQANCHMSA-N
24883	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5675	2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE	-	-	DRUGBANK	DB06854	C20H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LMGQGPVCSYOMNS-UHFFFAOYSA-N
24885	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5676	6-FLUORO-2-(2-HYDROXY-3-ISOBUTOXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE	-	-	DRUGBANK	DB06855	C18H19FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NSUDDASMRZSVON-UHFFFAOYSA-N
24886	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5677	6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE	-	-	DRUGBANK	DB06856	C22H24FN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HUYQYLFFFNSAAX-BUXKBTBVSA-N
24887	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5678	N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE	-	-	DRUGBANK	DB06857	C15H13ClIN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKGFTDAISIBIBV-UHFFFAOYSA-N
24906	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5696	N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE	-	-	DRUGBANK	DB06876	C24H24N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJWJKKXGAPWLGT-UHFFFAOYSA-N
24907	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5697	N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB06877	C16H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OPBUUQBZKJSWTN-UHFFFAOYSA-N
24912	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5702	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	-	-	DRUGBANK	DB06882	C24H25N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HJWMLCDGRWWLAQ-UHFFFAOYSA-N
24917	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5708	(13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25),18,20-HEPTAENE-23,26-DIONE	-	-	DRUGBANK	DB06888	C22H21N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBLPHMRCKHFBJB-OLZOCXBDSA-N
24919	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5712	(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide	-	-	DRUGBANK	DB06892	C15H12F3IN2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDLJJGJCIWWATJ-OOHURIHSSA-N
24958	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5752	N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide	-	-	DRUGBANK	DB06933	C24H24N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GJTCKUKIFXWJKG-UHFFFAOYSA-N
24963	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5759	N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide	-	-	DRUGBANK	DB06940	C19H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZZTMFGIGOADCFX-UHFFFAOYSA-N
24967	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5763	N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide	-	-	DRUGBANK	DB06944	C18H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIGZCVNCFXYBEG-UHFFFAOYSA-N
24968	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5763	N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide	-	-	DRUGBANK	DB06944	C18H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIGZCVNCFXYBEG-UHFFFAOYSA-N
24971	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5767	2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE	-	-	DRUGBANK	DB06948	C18H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XWWRLKIBRPJQJX-UHFFFAOYSA-N
24972	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5767	2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE	-	-	DRUGBANK	DB06948	C18H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XWWRLKIBRPJQJX-UHFFFAOYSA-N
24991	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5794	1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-(5-PYRROLIDIN-2-YL-1H-PYRAZOL-3-YL)-UREA	-	-	DRUGBANK	DB06976	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IWOOJEZSDPRYAZ-WFASDCNBSA-N
24994	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5798	(2S)-2-(1H-indol-3-yl)hexanoic acid	-	-	DRUGBANK	DB06980	C14H17NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCBHCHBXRBYJGU-NSHDSACASA-N
24995	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5799	(2S)-2-(1H-indol-3-yl)pentanoic acid	-	-	DRUGBANK	DB06981	C13H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QRCBLBWFQJDFJQ-JTQLQIEISA-N
24996	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5800	(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid	-	-	DRUGBANK	DB06982	C21H30N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWVCKFLATUTBCX-INIZCTEOSA-N
24997	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5801	(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol	-	-	DRUGBANK	DB06983	C19H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RBLKWWBHDUBPFN-UHFFFAOYSA-N
25004	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5809	N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide	-	-	DRUGBANK	DB06991	C17H22N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYOUIHFZUAKCEF-LLVKDONJSA-N
25024	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5828	N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07010	C21H17ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PDJZASCRQRBYQS-UHFFFAOYSA-N
25025	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5828	N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07010	C21H17ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PDJZASCRQRBYQS-UHFFFAOYSA-N
25027	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5831	TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE	-	-	DRUGBANK	DB07013	C22H31N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RXFCFGLSOUOCEA-UHFFFAOYSA-N
25033	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5838	N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide	-	-	DRUGBANK	DB07020	C20H14N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LMDMJDCLPIVGQD-UHFFFAOYSA-N
25037	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5842	2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE	-	-	DRUGBANK	DB07024	C19H17NO7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEXBEGBNDJVZPK-UHFFFAOYSA-N
25038	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5843	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB07025	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBIHHEGEALBUMT-UHFFFAOYSA-N
25039	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5844	(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE	-	-	DRUGBANK	DB07026	C20H21N3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PPLDARNGJSQINK-OKZBNKHCSA-N
25047	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5852	2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID	-	-	DRUGBANK	DB07034	C17H13NO7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOKATEXROYSXDW-UHFFFAOYSA-N
25049	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5855	(2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07037	C12H14N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBZPCTWLFNYBND-QMMMGPOBSA-N
25050	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5856	2-(cyclohexylamino)benzoic acid	-	-	DRUGBANK	DB07038	C13H17NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JSXMFCCPQQJLCR-UHFFFAOYSA-N
25054	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5864	2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide	-	-	DRUGBANK	DB07046	C16H14ClF2IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCADPEDUULETPK-SECBINFHSA-N
25060	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5872	(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL	-	-	DRUGBANK	DB07054	C22H23F4N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSCWQKTUILTARV-MRXNPFEDSA-N
25069	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5883	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07065	C19H12Cl2N6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHPKUZJCNHGFQA-UHFFFAOYSA-N
25079	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5893	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)-1H-INDAZOLE-6-CARBONITRILE	-	-	DRUGBANK	DB07075	C23H24N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WBKUBPBCFYCSRT-UHFFFAOYSA-N
25080	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5894	6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE	-	-	DRUGBANK	DB07076	C23H23N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWTQOPWAMQXIMI-UHFFFAOYSA-N
25082	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5896	(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB07078	C20H16N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYSXURJZVXBSRV-WJDWOHSUSA-N
25111	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5919	N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide	-	-	DRUGBANK	DB07101	C16H14F3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUDAHWBOROXANE-SECBINFHSA-N
25126	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5935	5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE	-	-	DRUGBANK	DB07117	C24H22N6O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMKQJGOROFNCGM-UHFFFAOYSA-N
25131	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5940	1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine	-	-	DRUGBANK	DB07122	C15H15N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MERNPSIIBFTCAI-UHFFFAOYSA-N
25134	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5944	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	-	-	DRUGBANK	DB07126	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWXORKPNCHJYOF-UHFFFAOYSA-N
25135	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5944	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	-	-	DRUGBANK	DB07126	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWXORKPNCHJYOF-UHFFFAOYSA-N
25138	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5947	(2R)-1-(2,6-dimethylphenoxy)propan-2-amine	-	-	DRUGBANK	DB07129	C11H17NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VLPIATFUUWWMKC-SNVBAGLBSA-N
25147	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5955	(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE	-	-	DRUGBANK	DB07137	C18H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPAWNIKVRIVDBT-PORMKJMCSA-N
25148	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5955	(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE	-	-	DRUGBANK	DB07137	C18H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPAWNIKVRIVDBT-PORMKJMCSA-N
25149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5956	5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one	-	-	DRUGBANK	DB07138	C19H9Cl2F2N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEPKQEUBKLEPRA-UHFFFAOYSA-N
25168	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5976	5-ETHYL-3-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]QUINOLIN-4-ONE	-	-	DRUGBANK	DB07158	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASEHARDUZDZEKS-UHFFFAOYSA-N
25173	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5981	5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE	-	-	DRUGBANK	DB07163	C17H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CQCXWWWNUFQYJS-UHFFFAOYSA-N
25174	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5982	N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine	-	-	DRUGBANK	DB07164	C13H12N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAGHIASAHLPQMS-UHFFFAOYSA-N
25175	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5982	N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine	-	-	DRUGBANK	DB07164	C13H12N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAGHIASAHLPQMS-UHFFFAOYSA-N
25186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5996	3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide	-	-	DRUGBANK	DB07179	C19H16BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DXUJQXZHHGJMFM-UHFFFAOYSA-N
25205	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6020	6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE	-	-	DRUGBANK	DB07203	C18H20ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUEGMEMDEAOAEG-UHFFFAOYSA-N
25206	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6020	6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE	-	-	DRUGBANK	DB07203	C18H20ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUEGMEMDEAOAEG-UHFFFAOYSA-N
25215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6027	3-bromo-5-phenyl-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07210	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JECHSYMSTXETFI-UHFFFAOYSA-N
25219	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6030	(5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL	-	-	DRUGBANK	DB07213	C24H25N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FNWHPLLNMLOZTL-UHFFFAOYSA-N
25224	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6033	N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide	-	-	DRUGBANK	DB07217	C16H13FN2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YVYPYORTKAIUGJ-UHFFFAOYSA-N
25225	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6034	6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE	-	-	DRUGBANK	DB07218	C12H10ClN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYKGPCNWPACUQV-UHFFFAOYSA-N
25228	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6036	N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE	-	-	DRUGBANK	DB07220	C23H27N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXYIRNXOAJYLCU-UHFFFAOYSA-N
25237	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6044	1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA	-	-	DRUGBANK	DB07228	C17H22ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIAYFZLMPSVQDV-NSHDSACASA-N
25245	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6050	3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	-	-	DRUGBANK	DB07234	C17H15N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MCBPNFWHHNJTGN-LLVKDONJSA-N
25253	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6059	(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE	-	-	DRUGBANK	DB07243	C16H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQGFCATXRXQKNB-GDNZZTSVSA-N
25257	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6062	(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE	-	-	DRUGBANK	DB07246	C16H15F3N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MKRPIBSCGZAUCH-OAHLLOKOSA-N
25276	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6080	(S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07264	C22H17Cl2FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YMUYGRBBEDYUOP-HXUWFJFHSA-N
25280	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6084	2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE	-	-	DRUGBANK	DB07268	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QHPKKGUGRGRSGA-UHFFFAOYSA-N
25284	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6088	N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE	-	-	DRUGBANK	DB07272	C18H19BrN4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKODDLYLEKSDJL-UHFFFAOYSA-N
25287	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6092	5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07276	C18H19N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEGKZYFYGCWXMN-UHFFFAOYSA-N
25297	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6101	(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID	-	-	DRUGBANK	DB07285	C11H12F2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OBQLOVWIRUXBAW-SECBINFHSA-N
25314	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6123	N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide	-	-	DRUGBANK	DB07307	C26H23N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GQXMJOSCBRZMKE-UHFFFAOYSA-N
25318	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6127	18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE	-	-	DRUGBANK	DB07311	C16H17ClN4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRSWWYITYIOHOP-UHFFFAOYSA-N
25321	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6130	1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA	-	-	DRUGBANK	DB07314	C14H12ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	URQYPXQXSVUVRG-UHFFFAOYSA-N
25327	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6136	4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID	-	-	DRUGBANK	DB07320	C25H27N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEDLHZCDTXWLOC-SGNKCFNYSA-N
25341	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6152	4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL	-	-	DRUGBANK	DB07336	C21H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GYPHGCGOSZJXOT-UHFFFAOYSA-N
25397	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6195	(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol	(2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol|Aminopurvalanol	-	DRUGBANK	DB07379	C19H26ClN7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAMROQQYRRQPDL-OAHLLOKOSA-N
25409	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6205	2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YL)-UREIDO]-N-METHYL-3-PHENYL-PROPIONAMIDE	-	-	DRUGBANK	DB07390	C13H15N5O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RKWXKADYTDWZIJ-VIFPVBQESA-N
25431	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6220	(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE	-	-	DRUGBANK	DB07406	C21H24N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QWFFPYQWUWLDBV-NSHDSACASA-N
25451	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6243	(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	-	-	DRUGBANK	DB07430	C21H18N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWRPDHVGMHLSZ-GFCCVEGCSA-N
25452	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6244	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	-	-	DRUGBANK	DB07431	C13H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXYKBKYDFZQOCB-SSDOTTSWSA-N
25453	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6244	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	-	-	DRUGBANK	DB07431	C13H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXYKBKYDFZQOCB-SSDOTTSWSA-N
25464	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6257	N-(biphenyl-4-ylsulfonyl)-D-leucine	-	-	DRUGBANK	DB07446	C18H21NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FBSVJQQVDISETN-QGZVFWFLSA-N
25475	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6270	4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE	-	-	DRUGBANK	DB07459	C19H16N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HVLSCZSVTCNAQX-UHFFFAOYSA-N
25484	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6282	5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE	-	-	DRUGBANK	DB07471	C22H20ClN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHCHLTQBLNUYRT-GFCCVEGCSA-N
25485	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6282	5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE	-	-	DRUGBANK	DB07471	C22H20ClN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHCHLTQBLNUYRT-GFCCVEGCSA-N
25516	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6304	(2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATE	-	-	DRUGBANK	DB07493	C16H9BrN2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IEQQJQHHJMQETK-YPKPFQOOSA-N
25523	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6312	(2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07501	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-KRWDZBQOSA-N
25526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6315	(2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07504	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-QGZVFWFLSA-N
25543	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6339	2-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONE	-	-	DRUGBANK	DB07529	C9H7N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LHGOQMPIWSCKBA-FNORWQNLSA-N
25546	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6341	4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07531	C14H10N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNPRTUHVCHGFHJ-GHXNOFRVSA-N
25547	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6343	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07533	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJJJERLTHDXEPT-JYRVWZFOSA-N
25548	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6343	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07533	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJJJERLTHDXEPT-JYRVWZFOSA-N
25549	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6344	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07534	C14H11N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKUMVXIXUVYKDQ-GHXNOFRVSA-N
25550	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6344	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07534	C14H11N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKUMVXIXUVYKDQ-GHXNOFRVSA-N
25553	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6348	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07538	C15H10F3N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGVVHQNJKUNSFQ-WDZFZDKYSA-N
25554	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6348	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07538	C15H10F3N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGVVHQNJKUNSFQ-WDZFZDKYSA-N
25555	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6349	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID	-	-	DRUGBANK	DB07539	C15H10N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLRKRQCTYQGDKJ-GHXNOFRVSA-N
25556	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6349	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID	-	-	DRUGBANK	DB07539	C15H10N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLRKRQCTYQGDKJ-GHXNOFRVSA-N
25557	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6350	4-{5-[(1Z)-1-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ETHYL]-2-FURYL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07540	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AKFVRSQELXTCFW-JYRVWZFOSA-N
25568	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6365	N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE	-	-	DRUGBANK	DB07556	C18H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSIZUMJRKYHEBR-QGZVFWFLSA-N
25569	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6365	N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE	-	-	DRUGBANK	DB07556	C18H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSIZUMJRKYHEBR-QGZVFWFLSA-N
25577	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6371	N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE	-	-	DRUGBANK	DB07562	C17H19N5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FGGSNQOBRJVAKL-UHFFFAOYSA-N
25578	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6371	N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE	-	-	DRUGBANK	DB07562	C17H19N5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FGGSNQOBRJVAKL-UHFFFAOYSA-N
25605	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6402	(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE	-	-	DRUGBANK	DB07595	C18H15BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WSIQKQLAGWVKSL-UHFFFAOYSA-O
25610	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6408	S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE	-	-	DRUGBANK	DB07602	C20H21N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLVZTRZPMRTVRC-INIZCTEOSA-N
25613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6412	6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE	-	-	DRUGBANK	DB07606	C20H15Cl3N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OPRAIFVPXXVXDL-UHFFFAOYSA-N
25614	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6413	4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB07607	C21H16IN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RXDZANYWRNIAOR-HHHXNRCGSA-N
25615	108192	1859	-	DYRK1A	DYRK|DYRK1|HP86|MNB|MNBH|MRD7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6414	N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide	-	-	DRUGBANK	DB07608	C24H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JDGOPNUGILVNJZ-IBGZPJMESA-N
25617	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6418	6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE	-	-	DRUGBANK	DB07612	C19H19F3N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XQKJVNGGVLHNLA-UHFFFAOYSA-N
25623	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6424	2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE	-	-	DRUGBANK	DB07618	C24H31N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AITZHKQVQNLKHI-UHFFFAOYSA-N
25626	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6428	1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA	-	-	DRUGBANK	DB07622	C21H23N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKQVGZXTNLQSV-UHFFFAOYSA-N
25629	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6431	4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide	-	-	DRUGBANK	DB07625	C21H28N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHTPPZCTHZHCQD-UHFFFAOYSA-N
25630	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6432	4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide	-	-	DRUGBANK	DB07626	C24H32ClN3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CKBBGCJYKCLKHE-UHFFFAOYSA-N
25653	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6453	(2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07647	C21H20N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VBASHTSSQNDDAS-CQSZACIVSA-N
25654	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6454	(2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL	-	-	DRUGBANK	DB07648	C21H20N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWEONIHFGKSPLC-MRXNPFEDSA-N
25657	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6459	N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE	-	-	DRUGBANK	DB07653	C20H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXTCEUDVOCLEJG-UHFFFAOYSA-N
25658	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6460	(5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC	-	-	DRUGBANK	DB07654	C21H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDJWWYRYKMXMKA-UHFFFAOYSA-N
25659	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6461	3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE	-	-	DRUGBANK	DB07655	C20H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MPJYGQHMIFDQIN-UHFFFAOYSA-N
25660	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6462	N-[4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL]-3-PYRIDIN-3-YLPROPANAMIDE	-	-	DRUGBANK	DB07656	C24H31N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UKQGSFUTDYQJST-UHFFFAOYSA-N
25666	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6468	N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE	-	-	DRUGBANK	DB07662	C17H13BrN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HTUBKQUPEREOGA-UHFFFAOYSA-N
25690	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6488	N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine	-	-	DRUGBANK	DB07683	C17H17NO4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZWYSEXQXOXWKA-INIZCTEOSA-N
25691	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6489	5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID	-	-	DRUGBANK	DB07684	C12H13NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VENHBDIMAAXWKI-UHFFFAOYSA-N
25692	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6490	4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07685	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMAZGYDYIYLSLJ-UHFFFAOYSA-N
25693	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6491	4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07686	C17H21N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPOGRVWIIVMWRI-UHFFFAOYSA-N
25694	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6492	4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07687	C17H22N8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVRKQJAEQWVSCM-HAQNSBGRSA-N
25695	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6493	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07688	C17H20N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPJIMTALCNCQLV-UHFFFAOYSA-N
25696	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6493	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07688	C17H20N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPJIMTALCNCQLV-UHFFFAOYSA-N
25724	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6521	3-(4-HYDROXY-PHENYL)PYRUVIC ACID	-	-	DRUGBANK	DB07718	C9H8O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KKADPXVIOXHVKN-UHFFFAOYSA-N
25733	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6529	2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB07728	C18H14FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJJYJNMNYDNXNO-UHFFFAOYSA-N
25734	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6529	2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB07728	C18H14FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJJYJNMNYDNXNO-UHFFFAOYSA-N
25736	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6532	4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL	-	-	DRUGBANK	DB07731	C9H10N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYZRKFOEZQBUEA-OUKQBFOZSA-N
25751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6551	(2R)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07750	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-MRXNPFEDSA-N
25752	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6552	(2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07751	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-HNNXBMFYSA-N
25763	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6556	(2S)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07755	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-INIZCTEOSA-N
25769	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6562	(2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07761	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-OAHLLOKOSA-N
25816	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6587	(3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE	-	-	DRUGBANK	DB07788	C19H22O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEQZWEXWOFPKOT-RCPUWQGCSA-N
25818	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6589	N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07790	C20H26N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LDXLQEXLXZCYSR-UHFFFAOYSA-N
25819	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6590	4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07791	C18H20N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MZWCVBFANHIPTJ-UHFFFAOYSA-N
25822	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6593	5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE	-	-	DRUGBANK	DB07794	C18H13N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XVECMUKVOMUNLE-UHFFFAOYSA-N
25823	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6594	3,7,3',4'-TETRAHYDROXYFLAVONE	-	-	DRUGBANK	DB07795	C15H10O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XHEFDIBZLJXQHF-UHFFFAOYSA-N
25833	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6609	N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide	-	-	DRUGBANK	DB07811	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBVTVSINEVHYSY-UHFFFAOYSA-N
25846	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6625	4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID	-	-	DRUGBANK	DB07827	C26H20N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FLTYDFYSVZBKOB-UHFFFAOYSA-N
25847	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6626	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE	-	-	DRUGBANK	DB07829	C14H10FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BILJSHVAAVZERY-UHFFFAOYSA-N
25850	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6629	4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde	-	-	DRUGBANK	DB07832	C20H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKQPTVJDZIILPG-UHFFFAOYSA-N
25851	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6630	N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide	-	-	DRUGBANK	DB07833	C24H18N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PMMLSQFPBFKLHH-UHFFFAOYSA-N
25852	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6631	N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	-	-	DRUGBANK	DB07834	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOHZGCHKLPIBBX-UHFFFAOYSA-N
25853	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6632	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide	-	-	DRUGBANK	DB07835	C22H24N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPSUAHGQHFKGG-UHFFFAOYSA-N
25869	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6642	2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide	-	-	DRUGBANK	DB07845	C22H21FN6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGYXXQRDIVRILX-UHFFFAOYSA-N
25876	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6649	1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID	-	-	DRUGBANK	DB07852	C10H7Cl2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CZTNDZALWLHXBA-UHFFFAOYSA-N
25877	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6649	1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID	-	-	DRUGBANK	DB07852	C10H7Cl2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CZTNDZALWLHXBA-UHFFFAOYSA-N
25918	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6685	3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER	-	-	DRUGBANK	DB07888	C12H13NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AIXMJTYHQHQJLU-SNVBAGLBSA-N
25919	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6686	1-(DIMETHYLAMINO)-3-(4-{{4-(2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PHENOXY)PROPAN-2-OL	-	-	DRUGBANK	DB07889	C23H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VCPXSBULBDYRLT-SFHVURJKSA-N
25929	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6701	(1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione	-	-	DRUGBANK	DB07905	C19H22O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SSNQAUBBJYCSMY-KNTMUCJRSA-N
25947	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6716	N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide	-	-	DRUGBANK	DB07920	C14H12N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGRPZMQLAVBWPV-UHFFFAOYSA-N
25948	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6717	2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide	-	-	DRUGBANK	DB07921	C8H7FN2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATANXIMWDMRRIO-UHFFFAOYSA-N
25949	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6718	N-oxo-2-(phenylsulfonylamino)ethanamide	-	-	DRUGBANK	DB07922	C8H8N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBEMJFIVKDOIBO-UHFFFAOYSA-N
25952	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6722	N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE	-	-	DRUGBANK	DB07926	C19H29N3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYZPDCGWIJYZMN-ZBFHGGJFSA-N
25964	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6732	N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine	-	-	DRUGBANK	DB07936	C24H30FN7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BACSZMCLZIDTIO-IBGZPJMESA-N
25966	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6737	3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide	-	-	DRUGBANK	DB07941	C22H19BrF2N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KCAJXIDMCNPGHZ-UHFFFAOYSA-N
25967	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6738	2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine	-	-	DRUGBANK	DB07942	C14H9F2N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJCHZVXSPFPKMX-UHFFFAOYSA-N
25968	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6739	2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07943	C20H20ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CATQHDWESBRRQA-UHFFFAOYSA-N
25978	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6745	1H-INDOL-3-YLACETIC ACID	-	-	DRUGBANK	DB07950	C10H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SEOVTRFCIGRIMH-UHFFFAOYSA-N
25991	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6754	3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE	-	-	DRUGBANK	DB07959	C14H10N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTKFRFMSUBOCIQ-UHFFFAOYSA-N
26009	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6777	2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07982	C23H29N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVTKDXZNSUHUMO-UHFFFAOYSA-N
26013	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6781	[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID	-	-	DRUGBANK	DB07986	C19H22N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNSLACGSDSJAIQ-UHFFFAOYSA-N
26014	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6782	[2-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YLCARBAMOYL)-1-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER	-	-	DRUGBANK	DB07987	C19H18N4O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWAKNMKLVLWIIQ-OAHLLOKOSA-N
26015	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6783	2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2YL)-UREIDO]-N-METHYL-3-PENTAFLUOROPHENYL-PROPIONAMIDE	-	-	DRUGBANK	DB07988	C13H10F5N5O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HZAXNPDJVFUGDS-BYPYZUCNSA-N
26031	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6798	4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide	-	-	DRUGBANK	DB08005	C20H23ClN6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARMFMDYRYOKSOW-UHFFFAOYSA-N
26036	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6803	(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime	-	-	DRUGBANK	DB08010	C25H19FN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DDHASJXGNUWZTM-ZLEWNXFRSA-N
26037	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6804	(3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime	-	-	DRUGBANK	DB08011	C17H12F2N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DXIHOIDYHQSQKJ-HMMYKYKNSA-N
26038	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6808	(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime	-	-	DRUGBANK	DB08015	C23H17FN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SZYREAUDQRVVLV-DAFNUICNSA-N
26045	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6814	5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide	-	-	DRUGBANK	DB08021	C18H17BrClN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEFJFXHHHNDHEN-UHFFFAOYSA-N
26047	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6816	N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine	-	-	DRUGBANK	DB08023	C18H21N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYNNWLVWJXWXFO-UHFFFAOYSA-N
26049	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6818	N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE	-	-	DRUGBANK	DB08025	C24H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACGBFWCBVIXTPZ-OQIWPSSASA-N
26050	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6819	2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide	-	-	DRUGBANK	DB08026	C19H23N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AJLILYAPRHIFAS-UHFFFAOYSA-N
26052	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6822	N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide	-	-	DRUGBANK	DB08029	C16H18N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QQDWEVONJRXVDB-UHFFFAOYSA-N
26053	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6823	3-[(4'-cyanobiphenyl-4-yl)oxy]-N-hydroxypropanamide	-	-	DRUGBANK	DB08030	C16H14N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XZWFHJUEAVOHHG-UHFFFAOYSA-N
26089	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6857	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	-	-	DRUGBANK	DB08064	C20H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NTMADESEDXKNFZ-UHFFFAOYSA-N
26092	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6859	N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE	-	-	DRUGBANK	DB08066	C17H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPKSFXFWECAIBR-UHFFFAOYSA-N
26094	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6861	N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-	-	-	DRUGBANK	DB08068	C23H25ClFN3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQJVDUKATDECHF-ICSRJNTNSA-N
26097	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6865	4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE	-	-	DRUGBANK	DB08072	C18H20Cl2N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYKUIRSGEMLIFT-UHFFFAOYSA-N
26119	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6884	3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE	-	-	DRUGBANK	DB08091	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIUFYIOMUILESI-UHFFFAOYSA-N
26120	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6885	3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide	-	-	DRUGBANK	DB08092	C19H18FN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMLSXFMXUNVCSK-UHFFFAOYSA-N
26121	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6886	3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE	-	-	DRUGBANK	DB08093	C16H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SZANYTFSQVBOBA-UHFFFAOYSA-N
26122	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6887	(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE	-	-	DRUGBANK	DB08094	C18H21F2N5O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRNJNYBQQYBCLE-UHFFFAOYSA-N
26123	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6888	3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA	-	-	DRUGBANK	DB08095	C23H26ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWYFTKPEHRQCCW-HNNXBMFYSA-N
26124	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6889	8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM	-	-	DRUGBANK	DB08096	C19H15ClF2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWKOUFZHPNIQSH-UHFFFAOYSA-N
26125	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6890	2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE	-	-	DRUGBANK	DB08097	C20H16F3N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGWSGDLIXOEZJG-UHFFFAOYSA-N
26141	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6914	N-METHYL-4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB08122	C16H15N3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKASAFLVQIJQOK-UVTDQMKNSA-N
26142	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6915	N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE	-	-	DRUGBANK	DB08123	C17H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GEWPSTLKJDIUHW-UHFFFAOYSA-N
26143	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6916	3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB08124	C20H15N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FTQYGMLRLRXBPT-IDUWFGFVSA-N
26144	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6917	4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB08125	C18H14N4O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOMPRXSVSIPRDT-PTNGSMBKSA-N
26145	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6918	3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE	-	-	DRUGBANK	DB08126	C16H15N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DMCRNUMVSATRTP-LCYFTJDESA-N
26148	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6922	N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine	-	-	DRUGBANK	DB08130	C16H13F3IN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPDWDLAITHFTTP-UHFFFAOYSA-N
26150	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6924	5-hydroxynaphthalene-1-sulfonamide	-	-	DRUGBANK	DB08132	C10H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFVBVKHGDDDCEA-UHFFFAOYSA-N
26151	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6925	N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide	-	-	DRUGBANK	DB08133	C14H12N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNHPHKFLWAPNOV-UHFFFAOYSA-N
26152	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6926	4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide	-	-	DRUGBANK	DB08134	C10H9ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RSNSGNZRUMHXAY-UHFFFAOYSA-N
26153	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6927	N-phenyl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08135	C10H9N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMZYZYFPPQOFKY-UHFFFAOYSA-N
26154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6928	4-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08136	C12H11FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CWQKPKYIMQTGJK-UHFFFAOYSA-N
26155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6929	(4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08137	C17H13FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZMWYSLJBNJUCRK-UHFFFAOYSA-N
26156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6930	{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08138	C17H11F3N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDRDBXXWQDFXEC-UHFFFAOYSA-N
26157	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6931	5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile	-	-	DRUGBANK	DB08139	C10H10ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFTLYNKTSANXFA-UHFFFAOYSA-N
26158	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6932	5-[(4-AMINOCYCLOHEXYL)AMINO]-7-(PROPAN-2-YLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE	-	-	DRUGBANK	DB08140	C16H23N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOESVLPZMGVWBM-JOCQHMNTSA-N
26159	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6933	4-{[(2,6-difluorophenyl)carbonyl]amino}-N-[(3S)-piperidin-3-yl]-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08141	C16H17F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KOMNQBZWMCFDTQ-VIFPVBQESA-N
26160	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6934	4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08142	C16H17Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVPNQJVDAFNBDN-UHFFFAOYSA-N
26203	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6970	4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08178	C12H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGEWEQJWGGJUHO-UHFFFAOYSA-N
26204	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6970	4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08178	C12H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGEWEQJWGGJUHO-UHFFFAOYSA-N
26208	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6974	4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08182	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZHMRPXZRUZLCNL-UHFFFAOYSA-N
26209	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6974	4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08182	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZHMRPXZRUZLCNL-UHFFFAOYSA-N
26228	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6999	2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE	-	-	DRUGBANK	DB08208	C17H13F3N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMNKRBRQQAMACZ-UHFFFAOYSA-N
26234	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7009	HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM	-	-	DRUGBANK	DB08218	C19H15N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLQVWKCQWFFUFJ-FCDQGJHFSA-N
26235	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7009	HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM	-	-	DRUGBANK	DB08218	C19H15N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLQVWKCQWFFUFJ-FCDQGJHFSA-N
26236	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7010	4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE	-	-	DRUGBANK	DB08219	C18H20N6OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPSZSAKYXPWBRR-RELWKKBWSA-N
26237	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7010	4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE	-	-	DRUGBANK	DB08219	C18H20N6OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPSZSAKYXPWBRR-RELWKKBWSA-N
26273	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7023	6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE	-	-	DRUGBANK	DB08233	C18H21N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFSDQDHHBKYQOD-UHFFFAOYSA-N
26274	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7023	6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE	-	-	DRUGBANK	DB08233	C18H21N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFSDQDHHBKYQOD-UHFFFAOYSA-N
26294	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7031	4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE	-	-	DRUGBANK	DB08241	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUUOIINPNMNPIU-UHFFFAOYSA-N
26295	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7031	4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE	-	-	DRUGBANK	DB08241	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUUOIINPNMNPIU-UHFFFAOYSA-N
26296	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7032	N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	-	-	DRUGBANK	DB08242	C20H18N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYTBZXSFNNAVKU-UHFFFAOYSA-N
26299	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7036	6-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINE	-	-	DRUGBANK	DB08247	C15H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JABXNQUXGJTKRO-UHFFFAOYSA-N
26300	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7037	3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE	-	-	DRUGBANK	DB08248	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKDUVKJYBJDZQW-UHFFFAOYSA-N
26301	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7037	3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE	-	-	DRUGBANK	DB08248	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKDUVKJYBJDZQW-UHFFFAOYSA-N
26317	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7059	N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID	-	-	DRUGBANK	DB08271	C13H20N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JIRXORZYIXSWOB-UHFFFAOYSA-N
26318	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7059	N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID	-	-	DRUGBANK	DB08271	C13H20N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JIRXORZYIXSWOB-UHFFFAOYSA-N
26319	110462	4319	-	MMP10	SL-2|STMY2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7059	N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID	-	-	DRUGBANK	DB08271	C13H20N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JIRXORZYIXSWOB-UHFFFAOYSA-N
26325	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7073	(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	-	-	DRUGBANK	DB08285	C19H26N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQUNOCMDMIQIQK-OAHLLOKOSA-N
26326	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7073	(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	-	-	DRUGBANK	DB08285	C19H26N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQUNOCMDMIQIQK-OAHLLOKOSA-N
26346	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7096	3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL	-	-	DRUGBANK	DB08309	C23H32N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMFGILNPFBVREA-UHFFFAOYSA-N
26347	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7096	3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL	-	-	DRUGBANK	DB08309	C23H32N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMFGILNPFBVREA-UHFFFAOYSA-N
26348	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7098	6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE	-	-	DRUGBANK	DB08312	C11H17N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGWXOLHKVGDQLN-UHFFFAOYSA-N
26375	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7119	4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME	-	-	DRUGBANK	DB08333	C14H17NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWZBYSBZDQWXGQ-XNTDXEJSSA-N
26376	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7120	3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME	-	-	DRUGBANK	DB08334	C14H16FNO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NPVNUGQNVVMJJP-CXUHLZMHSA-N
26377	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7121	4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME	-	-	DRUGBANK	DB08335	C13H17NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IRHAIEVALGHVLW-NTEUORMPSA-N
26396	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7134	N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide	-	-	DRUGBANK	DB08349	C24H21F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMEYCLAVMZKZCS-UHFFFAOYSA-N
26398	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7136	N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide	-	-	DRUGBANK	DB08351	C25H29N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNEXDVSJIUQQRH-UHFFFAOYSA-N
26399	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7137	6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine	-	-	DRUGBANK	DB08352	C19H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQYJTHIYAQQJAB-UHFFFAOYSA-N
26402	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7140	1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid	-	-	DRUGBANK	DB08355	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOBRPBVIEUWYJR-UHFFFAOYSA-N
26403	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7140	1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid	-	-	DRUGBANK	DB08355	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOBRPBVIEUWYJR-UHFFFAOYSA-N
26407	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7143	2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB08358	C21H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWFLADWRSCINST-UHFFFAOYSA-N
26408	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7143	2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB08358	C21H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWFLADWRSCINST-UHFFFAOYSA-N
26413	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7148	1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine	-	-	DRUGBANK	DB08363	C16H18N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBPNOEAFWYTTEB-UHFFFAOYSA-N
26434	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7172	5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE	-	-	DRUGBANK	DB08388	C20H19FN2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRSYNYGEEYTXJV-UHFFFAOYSA-N
26437	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7176	2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL	-	-	DRUGBANK	DB08392	C22H21N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARBUGBBNEFAECO-UHFFFAOYSA-N
26438	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7177	2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL	-	-	DRUGBANK	DB08393	C20H17N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQHINZSKNAAVOZ-UHFFFAOYSA-N
26440	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7179	2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE	-	-	DRUGBANK	DB08395	C22H18FN3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSOXFJURLPCSOO-UHFFFAOYSA-N
26452	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7187	METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID	-	-	DRUGBANK	DB08403	C18H27N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOPRTFSMCQNUCT-CABCVRRESA-N
26468	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7205	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	-	-	DRUGBANK	DB08423	C21H21FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKZZJXRGCHXIAI-UHFFFAOYSA-N
26469	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7206	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE	-	-	DRUGBANK	DB08424	C19H18FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJDQETGUEUJVTB-HNNXBMFYSA-N
26492	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7223	6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE	-	-	DRUGBANK	DB08441	C13H14BrN5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWSQADBSXFTFKL-UHFFFAOYSA-N
26514	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7244	(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol	-	-	DRUGBANK	DB08463	C24H29N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOCBJBNQIQQQGT-LJQANCHMSA-N
26515	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7244	(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol	-	-	DRUGBANK	DB08463	C24H29N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOCBJBNQIQQQGT-LJQANCHMSA-N
26529	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7263	[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER	-	-	DRUGBANK	DB08482	C19H35N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKRONJXEXGFBRZ-ZNMIVQPWSA-N
26536	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7270	CTS-1027	4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL]-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE|193022-04-7|RS-130830|Ro-1130830	-	DRUGBANK	DB08490	C19H20ClNO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ROSNVSQTEGHUKU-UHFFFAOYSA-N
26537	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7271	N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE	-	-	DRUGBANK	DB08491	C19H21NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARIRIZBKMKMEBD-UHFFFAOYSA-N
26548	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7286	N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID	-	-	DRUGBANK	DB08507	C20H27N2O3P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KGUVBHLPMGERAT-NIYFSFCBSA-N
26552	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7292	[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID	-	-	DRUGBANK	DB08513	C20H19N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAIQRYUOBBCBSE-UHFFFAOYSA-N
26570	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7299	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB08521	C21H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDMGBJANTYXAIV-HHHXNRCGSA-N
26571	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7299	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB08521	C21H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDMGBJANTYXAIV-HHHXNRCGSA-N
26572	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7300	4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE	-	-	DRUGBANK	DB08522	C18H16FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ROKOFZNQCIIJMI-UHFFFAOYSA-N
26575	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7305	1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08527	C15H12N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGAKLLFPOGATII-UHFFFAOYSA-N
26576	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7305	1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08527	C15H12N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGAKLLFPOGATII-UHFFFAOYSA-N
26579	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7309	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08531	C18H13Cl2N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CVYWYUAQFJMLEO-UHFFFAOYSA-N
26580	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7310	6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08532	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCNPGRRMPFCHEO-UHFFFAOYSA-N
26581	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7311	3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08533	C13H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LXRVAGIYXNQOKP-UHFFFAOYSA-N
26582	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7312	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08534	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZAIYYXVHGBMLEC-UHFFFAOYSA-N
26583	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7313	3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08535	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMIZFGZXFDGISG-UHFFFAOYSA-N
26584	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7314	3-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine	-	-	DRUGBANK	DB08536	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IBUPHWYGVDAASU-UHFFFAOYSA-N
26585	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7315	3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine	-	-	DRUGBANK	DB08537	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZLKFNBMXXLTLX-UHFFFAOYSA-N
26586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7316	N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08538	C19H17F2N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HQPVGVSQPQVZLD-UHFFFAOYSA-N
26587	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7317	3-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08539	C21H19N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCDIUVLNHCGSMH-UHFFFAOYSA-N
26597	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7333	1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline	-	-	DRUGBANK	DB08555	C16H13BrClNO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKGXHBGCVQTQBH-UHFFFAOYSA-N
26602	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7339	BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE	-	-	DRUGBANK	DB08561	C21H16N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLBINCOCFGQAJM-UHFFFAOYSA-N
26613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7349	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	-	-	DRUGBANK	DB08572	C18H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBKLJTXDSBEVRV-UHFFFAOYSA-N
26614	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7349	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	-	-	DRUGBANK	DB08572	C18H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBKLJTXDSBEVRV-UHFFFAOYSA-N
26631	110464	4321	-	MMP12	HME|ME|MME|MMP-12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7376	N-[(4-methoxyphenyl)sulfonyl]-D-alanine	-	-	DRUGBANK	DB08599	C10H13NO5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XTCIPBHRVYICGT-SSDOTTSWSA-N
26665	110458	4314	-	MMP3	CHDS6|MMP-3|SL-1|STMY|STMY1|STR1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7417	2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER	-	-	DRUGBANK	DB08643	C24H31N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFAWBPLETHINFK-UNMCSNQZSA-N
26684	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7447	4-[(5-ISOPROPYL-1,3-THIAZOL-2-YL)AMINO]BENZENESULFONAMIDE	-	-	DRUGBANK	DB08673	C12H15N3O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LPQUJAANWFHCJV-UHFFFAOYSA-N
26690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7451	N-(5-ISOPROPYL-THIAZOL-2-YL)-2-PYRIDIN-3-YL-ACETAMIDE	-	-	DRUGBANK	DB08677	C13H15N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZOOPQQADNJEG-UHFFFAOYSA-N
26692	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7457	REL-(9R,12S)-9,10,11,12-TETRAHYDRO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-1,3(2H)-DIONE	-	-	DRUGBANK	DB08683	C24H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTPNDVKVEAIXTI-IYBDPMFKSA-N
26721	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7468	9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol	-	-	DRUGBANK	DB08694	C14H11N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTHKPHCVZVYDFN-UHFFFAOYSA-N
26722	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7468	9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol	-	-	DRUGBANK	DB08694	C14H11N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTHKPHCVZVYDFN-UHFFFAOYSA-N
26726	111344	5328	RP11-417O11.1	PLAU	ATF|BDPLT5|QPD|UPA|URK|u-PA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7471	4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide	-	-	DRUGBANK	DB08697	C22H28ClN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JDYIYIRPQKMWMM-UHFFFAOYSA-N
26736	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7503	3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	-	-	DRUGBANK	DB08730	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPFBZMFUCGHBAP-UHFFFAOYSA-N
26752	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7524	N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE	-	-	DRUGBANK	DB08751	C12H15N5O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YSVJZZZGPPWEIC-UHFFFAOYSA-N
26765	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7538	6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE	-	-	DRUGBANK	DB08765	C7H6N2O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NOOBQTYVTDBXTL-UHFFFAOYSA-N
26768	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7541	N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE	-	-	DRUGBANK	DB08768	C10H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYVABZIGRDEKCD-UHFFFAOYSA-N
26775	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7546	1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine	-	-	DRUGBANK	DB08774	C17H19N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBRZCAKSBYWZTC-ZDUSSCGKSA-N
26777	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7548	N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE	-	-	DRUGBANK	DB08776	C9H11N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYHOEDBNAJPFKK-UHFFFAOYSA-N
26778	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7549	5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE	-	-	DRUGBANK	DB08777	C10H10N2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMMOEJUJKIXUQZ-UHFFFAOYSA-N
26779	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7550	[4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone	-	-	DRUGBANK	DB08778	C14H17N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KEHNGAHNKVLUSC-UHFFFAOYSA-N
26780	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7551	2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol	-	-	DRUGBANK	DB08779	C9H10N2OS2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QWYGHJVEZLVLSU-UHFFFAOYSA-N
26781	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7552	6-MORPHOLIN-4-YL-9H-PURINE	-	-	DRUGBANK	DB08780	C9H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEOMXKNIFWDDGZ-UHFFFAOYSA-N
26782	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7553	1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE	-	-	DRUGBANK	DB08781	C11H14BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BJUBFXSKTBULRW-ZETCQYMHSA-N
26846	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	inhibitor	target	Sustar V (2009)	19261492	182099	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26847	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	inhibitor	target	Nagy Z (2009)	19757196	182127	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26850	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Anninos H (2009)	19465361	182109	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26851	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Zhang W (2005)	15678110	181880	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26852	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Gomez-Isla T (2008)	18317243	182067	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26853	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Whitehead SN (2007)	17194886	181980	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26951	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	binder	target	Browning DJ (2012)	22813448	182207	7629	Aflibercept	VEGF Trap|Ziv-Aflibercept|VEGF Trap-Eye	eylea|zaltrap	DRUGBANK	DB08885	C4318H6788N1164O1304S32	biologic	L01XX44|S01LA05	862111-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26953	111249	5228	-	PGF	D12S1900|PGFL|PLGF|PlGF-2|SHGC-10760	9606	Homo sapiens	binder	target	Browning DJ (2012)	22813448	182207	7629	Aflibercept	VEGF Trap|Ziv-Aflibercept|VEGF Trap-Eye	eylea|zaltrap	DRUGBANK	DB08885	C4318H6788N1164O1304S32	biologic	L01XX44|S01LA05	862111-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26954	108621	2335	-	FN1	CIG|ED-B|FINC|FN|FNZ|GFND|GFND2|LETS|MSF	9606	Homo sapiens	cleavage	target	Tsui I (2012)	23193358	182220	7632	Ocriplasmin	-	jetrea	DRUGBANK	DB08888	C1214H1890N338O348S14	biologic	S01XA22	1048016-09-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26980	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	neutralizer	target	Chimenti MS (2013)	23620660	182248	7648	Certolizumab pegol	CDP870	cimzia	DRUGBANK	DB08904	C2115H3252N556O673S16	biologic	L04AB05	428863-50-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26984	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	inhibitor	target	Gertz MA (2013)	22917017	182210	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
26988	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Ferguson GD (2007)	17308870	159982	7654	Pomalidomide	-	pomalyst	DRUGBANK	DB08910	C13H11N3O4	small molecule	L04AX06	19171-19-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UVSMNLNDYGZFPF-UHFFFAOYNA-N
26990	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Salama AK (2013)	23432625	182233	7655	Trametinib	JTP 74057|GSK 1120212|Trametinib Dimethyl Sulfoxide|Trametinibum	mekinist	DRUGBANK	DB08911	C26H23FIN5O4	small molecule	L01XE25	871700-17-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LIRYPHYGHXZJBZ-UHFFFAOYSA-N
27039	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27040	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	61	Human Serum Albumin	Human albumin|Albumin human|Albumin microspheres, human|Albumin (human)|Albumin, human|Albumin, blood|Serum albumin	sterile diluent for allergenic	DRUGBANK	DB00062	C2936H4624N786O889S41	biologic	-	9048-46-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27041	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Danesh J (1999)	10361047	172127	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27042	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27043	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27044	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Grehan S (1997)	9200475	172129	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27045	112196	6288	-	SAA1	PIG4|SAA|SAA2|TP53I4	9606	Homo sapiens	unknown	target	Danesh J (2000)	10903648	172128	63	Serum albumin iodonated	Serum albumin precursor	-	DRUGBANK	DB00064	C2936H4624N786O889S41	biologic	-	9048-49-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27146	113255	7412	-	VCAM1	CD106|INCAM-100	9606	Homo sapiens	unknown	target	Arevalo E (2008)	18165316	188487	888	Ethanol	thanol|Methylcarbinol|Ethyl Alcohol|Alcohol|Alcohol etlico|thylalkohol|Grain alcohol|Alcohol (ethyl)|1-Hydroxyethane|Alcohol anhydrous|thanol|Alcohol, denatured|etanol|Dehydrated ethanol|Spiritus vini|Hydroxyethane|Alkohol|Alcool thylique|Alcohol denatured	lisa frank bubblegum antisepti	DRUGBANK	DB00898	C2H6O	small molecule	D08AX08|V03AB16|V03AZ01	64-17-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFQSCWFLJHTTHZ-UHFFFAOYSA-N
27364	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Singh A (2015)	26384788	188510	5018	Cobimetinib	-	cotellic	DRUGBANK	DB05239	C21H21F3IN3O2	small molecule	-	934660-93-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSMCAPRUBJMWDF-KRWDZBQOSA-N
27375	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1998)	9850732	172163	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27376	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (2001)	11327694	172166	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27377	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Locci P (1995)	7648625	172165	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27378	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1997)	9435505	172164	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27422	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Talley JJ (2000)	10794682	188524	7221	Parecoxib	-	-	DRUGBANK	DB08439	C19H18N2O4S	small molecule	M01AH04	198470-84-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZRHLKRLEZJVIJ-UHFFFAOYSA-N
27457	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	van Zaanen HC (1996)	8823310	188534	7799	Siltuximab	-	sylvant	DRUGBANK	DB09036	C6450H9932N1688O2016S50	biologic	L04AC11	541502-14-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27458	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antibody	target	van Zaanen HC (1996)	8823310	188534	7799	Siltuximab	-	sylvant	DRUGBANK	DB09036	C6450H9932N1688O2016S50	biologic	L04AC11	541502-14-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27477	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	inhibitor	target	Fry DW (2004)	15542782	188549	7820	Palbociclib	6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one	ibrance	DRUGBANK	DB09073	C24H29N7O2	small molecule	L01XE33	571190-30-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHJRHEGDXFFMBM-UHFFFAOYSA-N
27478	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	inhibitor	target	Fry DW (2004)	15542782	188549	7820	Palbociclib	6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one	ibrance	DRUGBANK	DB09073	C24H29N7O2	small molecule	L01XE33	571190-30-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHJRHEGDXFFMBM-UHFFFAOYSA-N
27521	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	unknown	target	McCann ME (2004)	15077695	188559	7961	Firocoxib	-	-	DRUGBANK	DB09217	C17H20O5S	small molecule	-	189954-96-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FULAPETWGIGNMT-UHFFFAOYSA-N
27585	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	inhibitor	target	Zheng L (2007)	17259377	181291	926	Salicylic acid	2-Carboxyphenol|2-Hydroxybenzoic acid|O-hydroxybenzoic acid|O-carboxyphenol	md cell scalp|neutrogena oil f	DRUGBANK	DB00936	C7H6O3	small molecule	N02BA04|D01AE12|S01BC08	69-72-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YGSDEFSMJLZEOE-UHFFFAOYSA-N
27638	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	8061	Isopropyl Alcohol	-	labsco sterile alcohol prep pa	DRUGBANK	DB02325	C3H8O	small molecule	-	67-63-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KFZMGEQAYNKOFK-UHFFFAOYSA-N
27850	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	inhibitor	target	Cicardi M (2005)	16267649	195964	7771	C1 Esterase Inhibitor (Human)	C1 inhibitor|hC1INH|C1-esterase inhibitor, human|C1INH|C1-inhibiting factor|Human C1 inhibitor|Complement C1 esterase inhibitor|C1-inhibitor, plasma derived|Plasma protease C1 inhibitor|C1 inhibitor (human)|C1 inhibitor human|C1-INH|Human C1-esterase inhibitor	berinert 1500|berinert|beriner	DRUGBANK	DB06404	-	biologic	B06AC01	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27925	111343	5327	-	PLAT	T-PA|TPA	9606	Homo sapiens	inhibitor	target	Cicardi M (2005)	16267649	195964	7972	C1 Esterase Inhibitor (Recombinant)	C1 Inhibitor (Recombinant)|C1-INH|Conestat Alfa|C1INH	ruconest	DRUGBANK	DB09228	-	biologic	B06AC04	80295-38-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27930	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	inhibitor	target	Yosaatmadja Y (2015)	26522274	196035	8129	Osimertinib	N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide|Mereletinib	tagrisso	DRUGBANK	DB09330	C28H33N7O2	small molecule	-	1421373-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUYJMQONPNNFPI-UHFFFAOYSA-N
27933	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Kuenen B (2010)	20197484	195996	8209	Necitumumab	-	portrazza	DRUGBANK	DB09559	-	biologic	L01XC22	906805-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
28022	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2014)	25375378	206180	8422	Bivalent ligand 5	Bivalent_ligand_5|SNIPER(TACC3)-1/SNIPER(TACC3)-2|SNIPER(TACC3)-1|SNIPER(TACC3)-2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(TACC3)-1(cIAP1:bestatin --- TACC3:KHS108)	-
28030	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited E3 ligase	Schneekloth AR (2008)	18752944	85706	8420	Bivalent ligand 9	Bivalent_ligand_9|PROTAC 14|Protac-14	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 14(MDM2:nutlin-3 --- AR:SARM)	-
28121	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	degradation	target	Tomoshige S (2015)	26338696	191691	8399	Bivalent ligand 48	Bivalent_ligand_48|compound 1b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: compound 1b(cIAP1:BE04 --- HaloTag-c-jun)	-
28123	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	degradation	target	Tomoshige S (2016)	27236416	205947	8400	Bivalent ligand 49	Bivalent_ligand_49|Compound 4a/4b|Compound 4a|Compound 4b|4a|4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: Compound 4a/4b(IAP pan-ligand:MV1 --- HaloTag-TNFalpha)	-
28127	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	degradation	target	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-ERK1)	-
28129	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-MEK1)	-
28139	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Burslem GM (2018)	29129716	211414	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: compound 1(VHL:Ligand 9 --- EGFR:lapatinib)	-
28141	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Burslem GM (2018)	29129716	211414	8439	Bivalent ligand 53	Bivalent_ligand_53|COMPOUND 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: compound 3(VHL:Ligand 9 --- EGFR:gefitinib)	-
28143	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Burslem GM (2018)	29129716	211414	8442	Bivalent ligand 54	Bivalent_ligand_54|COMPOUND 3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: compound 4(VHL:Ligand 9 --- EGFR:afatinib)	-
28163	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPK14:foretinib)	-
28175	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK3:foretinib)	-
28197	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK2:foretinib)	-
28398	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24900784	211364	8355	RO5353	Spiro[pyrrolidine-3,6'-[6H]thieno[3,2-b]pyrrole]-5-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-4',5'-dihydro-5'-oxo-, (2S,3R,4R,5R)-|(2S,3R,4R,5R)-N-(4-Carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide	-	CHEMSPIDER	31135029	C29H29Cl2FN4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UOVSZRTTWLJPHE-HNXAPSNLSA-N
28399	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24900784	211364	8356	RO2468	(2S,3R,4S,5R)-N-(4-Carbamoyl-2-methoxyphenyl)-6'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-2'-oxo-1',2'-dihydrospiro[pyrrolidine-3,3'-pyrrolo[3,2-c]pyridine]-5-carboxamide	-	CHEMSPIDER	31135031	C30H30Cl2FN5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CGCOPBXAGSCZNX-FNQJWKMRSA-N
28400	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Tan G (2017)	28549433	207226	8357	JS-K	Ethyl 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-1-piperazinecarboxylate|1-Piperazinecarboxylic acid, 4-[(E)-(2,4-dinitrophenoxy)-NNO-azoxy]-, ethyl ester	-	CHEMSPIDER	24684273	C13H16N6O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DNJRNBYZLPKSHV-XMHGGMMESA-N
28420	112391	6500	-	SKP1	EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A	9606	Homo sapiens	inhibitor	target	Liu YQ (2015)	26474281	191844	8370	6-OAP	(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-butenoate|2-Butenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester, (2Z)-	-	CHEMSPIDER	21246838	C20H26O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KUPPZVXLWANEJJ-UXPPPGSFSA-N
28430	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Tovar C (2013)	23400593	211352	8379	RG7112	RO-5045337|Q8MI0X869M|{(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}{4-[3-(methylsulfonyl)propyl]-1-piperazinyl}methanone|Methanone, [(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]-	-	CHEMSPIDER	28189760	C38H48Cl2N4O4S	small molecule	-	939981-39-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBGKPEROWUKSBK-QPPIDDCLSA-N
28431	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ding Q (2013)	23808545	211356	8380	RG7388	idasanutlin|4-{[(3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-D-prolyl]amino}-3-methoxybenzoic acid|Benzoic acid, 4-[[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxy-	-	CHEMSPIDER	30831264	C31H29Cl2F2N3O4	small molecule	-	1229705-06-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TVTXCJFHQKSQQM-LJQIRTBHSA-N
28432	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Bill KL (2016)	26475335	211379	8381	SAR405838	8570LZ3RCA|SAR-405838|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	30811498	C29H34Cl2FN3O3	small molecule	-	1303607-60-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IDKAKZRYYDCJDU-HBMMIIHUSA-N
28433	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Shangary S (2008)	18316739	208243	8382	MI-219	(2'R,3R,4'R,5'R)-6-Chloro-4'-(3-chlorophenyl)-N-[(3S)-3,4-dihydroxybutyl]-5-fluoro-2'-(2-methyl-2-propanyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chlorophenyl)-N-[(3S)-3,4-dihydroxybutyl]-2'-(1,1-dimethylethyl)-5-fluoro-1,2-dihydro-2-oxo-, (2'R,3R,4'R,5'R)-	-	CHEMSPIDER	59695355	C26H30Cl2FN3O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KUMSTKUNLHZBEQ-MWFJYFKBSA-N
28495	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	inhibitor	target	Zeng X (2010)	20951947	139860	8463	TAMe	TAME|tosyl-arginine methyl ester|tosyl-L-arginine methyl ester|Ts-Arg-OMe|p-toluensulfonyl-L-arginine methyl ester|Nalpha-p-tosyl-L-arginine methyl ester|methyl N2-(p-tosyl)-L-argininate|methyl N2-(p-toluenenesulfonyl)-L-argininate|methyl N2-[(p-tolyl)sulphonyl]-L-argininate|N2-(p-tolylsulfonyl)-L-arginine methyl ester|methyl N2-[(4-methylphenyl)sulfonyl]-L-argininate	-	CHEBI	62167	C14H22N4O4S	small molecule	-	1784-03-08	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FKMJXALNHKIDOD-LBPRGKRZSA-N
28505	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhou Y (2018)	29670376	212575	8591	Butein	Butein|Chalcone, 2',3,4,4'-tetrahydroxy- (7CI,8CI)|2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one|(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one|2056928|4WVS5M0LGF|(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one[	-	CHEMSPIDER	4444634	C15H12O5	small molecule	-	487-52-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AYMYWHCQALZEGT-ORCRQEGFSA-N
28525	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Lu J (2016)	27764791	216708	8381	SAR405838	8570LZ3RCA|SAR-405838|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, 6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	30811498	C29H34Cl2FN3O3	small molecule	-	1303607-60-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IDKAKZRYYDCJDU-HBMMIIHUSA-N
28529	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Sznarkowska A (2019)	30603043	218393	2193	Protoporphyrin Ix	protoporphyrin IX|protoporphyrin|553-12-8|Ooporphyrin|Protoporpyrin IX|ppIX|Porphyrinogen IX|Protoporphyrin IX disodium|Kammerers prophyrin	-	DRUGBANK	DB02285	C34H33N4O4	small molecule	-	553-12-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	PpIX ablates TAp73/MDM2, TAp73/MDMX and TAp73/Itch complexes	-
28530	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Sznarkowska A (2019)	30603043	218393	2193	Protoporphyrin Ix	protoporphyrin IX|protoporphyrin|553-12-8|Ooporphyrin|Protoporpyrin IX|ppIX|Porphyrinogen IX|Protoporphyrin IX disodium|Kammerers prophyrin	-	DRUGBANK	DB02285	C34H33N4O4	small molecule	-	553-12-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	PpIX ablates TAp73/MDM2, TAp73/MDMX and TAp73/Itch complexes	-
28540	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Lain S (2008)	18455128	78113	8621	Tenovin-1	N-[4-({[(4-tert-butylbenzoyl)amino]carbothioyl}amino)phenyl]acetamide|Tenovin-1|N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide|Benzamide, N-[[[4-(acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-|N-[(4-Acetamidophenyl)carbamothioyl]-4-(2-methyl-2-propanyl)benzamide|N-[(4-acetamidoanilino)-sulfanylidenemethyl]-4-tert-butylbenzamide|BIQ6AID2B7	-	CHEMSPIDER	875023	C20H23N3O2S	small molecule	-	380315-80-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	Tenovin-1 protects against MDM2-mediated p53 degradation and inhibits the protein deacetylating activities of SirT1 and SirT2.	WOWJIWFCOPZFGV-UHFFFAOYSA-N
28541	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Thompson T (2010)	20406950	223663	8606	Serdemetan	Serdemetan|1,4-Benzenediamine, N~1~-[2-(1H-indol-3-yl)ethyl]-N~4~-4-pyridinyl-|N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine|9161|ID6YB4W3V8	-	CHEMSPIDER	9784341	C21H20N4	small molecule	-	881202-45-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CEGSUKYESLWKJP-UHFFFAOYSA-N
28542	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Wang H (2011)	21075910	223664	8619	7-(4-Methyl-1-piperazinyl)-4-nitro-2,1,3-benzoxadiazole 1-oxide	7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide|2,1,3-Benzoxadiazole, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide|7-(4-Methyl-1-piperazinyl)-4-nitro-2,1,3-benzoxadiazole 1-oxide	-	CHEMSPIDER	38890	C11H13N5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MWFZDJLPWDCQIL-UHFFFAOYSA-N
28543	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Issaeva N (2004)	15558054	144968	8582	RITA (NSC 652287)	(Furan-2,5-diyldithiene-5,2-diyl)dimethanol|2-Thiophenemethanol, 5,5'-(2,5-furandiyl)bis-|RITA (NSC 652287)|(2,5-Furandiyldi-5,2-thienediyl)dimethanol|[5-[5-[5-(hydroxymethyl)-2-thiophenyl]-2-furanyl]-2-thiophenyl]methanol	-	CHEMSPIDER	332269	C14H12O3S2	small molecule	-	213261-59-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	RITA binds to p53 and blocks the p53MDM2 interaction	KZENBFUSKMWCJF-UHFFFAOYSA-N
28544	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ma T (2012)	22166212	220337	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
28552	113169	7321	-	UBE2D1	E2(17)KB1|SFT|UBC4/5|UBCH5|UBCH5A	9606	Homo sapiens	inhibitor	target	Chen H (2017)	28696694	208509	8572	UbcH5c-IN-1	(3aS,9bR)-8-[(2-Bromobenzyl)oxy]-6,9-dimethyl-3-methylene-3a,4,5,9b-tetrahydronaphtho[1,2-b]furan-2(3H)-one|Naphtho[1,2-b]furan-2(3H)-one, 8-[(2-bromophenyl)methoxy]-3a,4,5,9b-tetrahydro-6,9-dimethyl-3-methylene-, (3aS,9bR)-	-	CHEMSPIDER	71061570	C22H21BrO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IRBNWCSCHCJSLT-LAUBAEHRSA-N
28568	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	De Cesare V (2018)	30017913	216529	786	Candesartan	2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid|Candesartan cilexetil|CV-11974|2-Ethoxy-1-(P-(O-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid|Blopress|2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid	auro-candesartan|atacand plus|	DRUGBANK	DB00796	C24H20N6O3	small molecule	C09DB07|C09DA06|C09CA06	139481-59-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Positive hit in high screen assay validated by IC-50 determination.	HTQMVQVXFRQIKW-UHFFFAOYSA-N
28601	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	degradation	target	Smith BE (2019)	30631068	219514	8512	Bivalent ligand 72	SJFa PROTAC|Bivalent_ligand_72	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	SJFalpha PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28603	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	degradation	target	Smith BE (2019)	30631068	219514	8511	Bivalent ligand 73	SJFd PROTAC|Bivalent_ligand_73	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	SJFDelta PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28609	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Brand M (2019)	30595531	214853	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	BSJ-03-123|Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28613	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Rana S (2019)	30935795	215476	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28616	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Hines J (2019)	30385614	215621	8518	Bivalent ligand 78	A1874|Bivalent_ligand_78	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: A1874(MDM2:idasanutlin --- BRD4:JQ1)	-
28621	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	target	Li Y (2019)	30525597	223612	8490	Bivalent ligand 82	MD-224|Bivalent_ligand_82	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MD-224 (CRBN:lenalidomide --- MDM2:MI-1061)	-
28625	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Burslem GM (2018)	29129716	211414	8492	Bivalent ligand 84	Compound 1|Bivalent_ligand_84	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 1 (VHL: compound 15 --- EGFR:lapatinib)	-
28667	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Wei J (2019)	31730343	223618	8508	Bivalent ligand 102	MS432N|Bivalent_ligand_102	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS432N(VHL:VHL1 --- MAP2K1:PD0325901)	-
28682	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Q (2019)	30540295	223621	8505	Bivalent ligand 107	compound-3|Bivalent_ligand_107	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: compound-3 (MDM2:nutlin-3 --- PARP1:niraparib)	-
28697	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Bai L (2019)	31715132	223626	8467	Bivalent ligand 113	SD-36|Bivalent_ligand_113	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SD-36 (CRBN:lenalidomide --- STAT3:SI-109)	-
28749	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
28751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
28755	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
28757	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- PRKAA1:TL13-87)	-
28781	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK3:Probe 1)	-
28783	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK1:Probe 1)	-
28837	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Banik SM (2020)	32728216	223640	8526	Bivalent ligand 136	Ab-2|Bivalent_ligand_136	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	109703	3482	-	IGF2R	CD222|CIMPR|M6P-R|MPR1|MPRI	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: Ab-2 (IGF2R:M6Pn glycopolypeptide ligand --- EGFR:cetuximab)	-
28887	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Crew AP (2018)	28692295	217494	8488	Bivalent ligand 80	PROTAC 3i|Bivalent_ligand_80	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 3i (VHL:VHL ligand 2 ---TBK1:ligand 1b)	-
28905	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HRAS:RASabHaloTag)	-
28913	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK14:PH-797804)	-
28915	111586	5600	-	MAPK11	P38B|P38BETA2|PRKM11|SAPK2|SAPK2B|p38-2|p38Beta	9606	Homo sapiens	degradation	target	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK11:PH-797804)	-
28937	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK4:palbociclib)	-
28939	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK6:palbociclib)	-
28941	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK4:ribociclib)	-
28943	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK6:ribociclib)	-
28945	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK4:abemaciclib)	-
28947	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK6:abemaciclib)	-
28951	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8479	Bivalent ligand 166	BSJ-01-187|Bivalent_ligand_166	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01187 (CRBN:thalidomide --- CDK4:ribociclib)	-
28953	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8480	Bivalent ligand 167	YKL-06-102|Bivalent_ligand_167	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL06102 (CRBN:thalidomide --- CDK6:palbociclib)	-
28967	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK4:palbociclib)	-
28969	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK6:palbociclib)	-
28971	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8474	Bivalent ligand 169	BSJ-04-132|Bivalent_ligand_169	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ04132 (CRBN:thalidomide --- CDK4:ribociclib)	-
28973	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8472	Bivalent ligand 170	BSJ-03-123|Bivalent_ligand_170	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03123 (CRBN:thalidomide --- CDK6:palbociclib)	-
29126	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Holzer P (2015)	26181851	224770	9193	Nvp-cgm097	ZINC253387855|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-[METHYL-[[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-7-PROPAN-2-YLOXY-1,4-DIHYDROISOQUINOLIN-3-ONE|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-[METHYL[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)-TRANS-CYCLOHEXYLMETHYL]AMINO]PHENYL)-1,4-DIHYDRO-2H-ISOQUINOLIN-3-ONE|4UF6MSL0ZH|NVP-CGM-097|KS-00000TSY|CCG-270337|US9051279, 106|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-(METHYL{[TRANS-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL}AMINO)PHENYL]-7-(PROPAN-2-YLOXY)-1,4-DIHYDROISOQUINOLIN-3(2H)-ONE|EX-A1059|CS-3138|HY-15954|NVP-CGM097 (CGM-097)|NVP-CGM097|Q27454942|NCGC00390552-01|W5747|4T4|NVP CGM097|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-{4-[METHYL({[(1R,4R)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL})AMINO]PHENYL}-7-(PROPAN-2-YLOXY)-1,2,3,4-TETRAHYDROISOQUINOLIN-3-ONE|C38H47CLN4O4|1313363-54-0|(1S)-1-(4-CHLOROPHENYL)-1,4-DIHYDRO-6-METHOXY-7-(1-METHYLETHOXY)-2-[4-[METHYL[[TRANS-4-(4-METHYL-3-OXO-1-PIPERAZINYL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-3(2H)-ISOQUINOLINONE|CGM-097|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-(METHYL(((1R,4S)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL)METHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE|UNII-4UF6MSL0ZH|A16326|AS-75288|S7875|CGM097|J3.509.326E|CGM 097|BCP18308|AKOS030526402|BDBM162123	-	PUBCHEM	53240420	C38H47ClN4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CLRSLRWKONPSRQ-CPOWQTMSSA-N
29139	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9206	[(2S,4R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-4-fluoropyrrolidin-2-yl]-[(6R)-6-ethyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	BDBM50069632	-	PUBCHEM	46840822	C34H38Cl2F2N6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QUYOIFDRHGZSFZ-YABFKZQLSA-N
29140	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9207	[(2S,4R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-4-fluoropyrrolidin-2-yl]-[(6S)-6-methyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	[(2S,4R)-1-[(5R,6S)-5-(4-CHLORO-3-FLUOROPHENYL)-6-(6-CHLOROPYRIDIN-3-YL)-6-METHYL-3-PROPAN-2-YL-5H-IMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBONYL]-4-FLUOROPYRROLIDIN-2-YL]-[(6S)-6-METHYL-4,7-DIAZASPIRO[2.5]OCTAN-7-YL]METHANONE|(6S)-7-[(4R)-1-{[(5R,6S)-5-(4-CHLORO-3-FLUOROPHENYL)-6-(6-CHLOROPYRIDIN-3-YL)-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOL-2-YL]CARBONYL}-4-FLUORO-L-PROLYL]-6-METHYL-4,7-DIAZASPIRO[2.5]OCTANE|BDBM50069631	-	PUBCHEM	46840819	C33H36Cl2F2N6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OKIDBNYMCUVSLU-QSSUNTQZSA-N
29141	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9208	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-[(6S)-6-methyl-4,7-diazaspiro[2.5]octan-7-yl]methanone	BDBM50069630	-	PUBCHEM	87252803	C34H39Cl2FN6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KUZMUIBQNCSWPP-BYJYTBDMSA-N
29142	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9209	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069629	-	PUBCHEM	87252745	C33H37Cl2FN6O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FZPRQVYQBJKIQG-KERGWKIMSA-N
29143	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9210	[(2S,5R)-1-[(5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069628	-	PUBCHEM	67058381	C34H38Cl2FN5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LIFXVTDIRXSOPW-ZNGXGWPMSA-N
29144	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9211	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069627	-	PUBCHEM	44596000	C34H39Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XLBQSMBISPUIMT-MAMXRPNDSA-N
29145	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9212	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-(4-methyl-4,7-diazaspiro[2.5]octan-7-yl)methanone	BDBM50069626	-	PUBCHEM	67058380	C35H41Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZCAFJDRQRAWKAO-GRZVAKJNSA-N
29146	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Miyazaki M (2015)	25882531	224772	9213	[(2S,5R)-1-[(5R,6S)-5,6-Bis(4-chlorophenyl)-6-methyl-3-propan-2-yl-5H-imidazo[2,1-b][1,3]thiazole-2-carbonyl]-5-methylpyrrolidin-2-yl]-[(3R)-3,4-dimethylpiperazin-1-yl]methanone	(5R,6S)-5,6-BIS(4-CHLOROPHENYL)-2-[((2S,5R)-2-{[(3R)-3,4-DIMETHYLPIPERAZIN-1-YL]CARBONYL}-5-METHYLPYRROLIDIN-1-YL)CARBONYL]-3-ISOPROPYL-6-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE|[(2S,5R)-1-[(5R,6S)-5,6-BIS(4-CHLOROPHENYL)-6-METHYL-3-PROPAN-2-YL-5H-IMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBONYL]-5-METHYLPYRROLIDIN-2-YL]-[(3R)-3,4-DIMETHYLPIPERAZIN-1-YL]METHANONE|BDBM50069625	-	PUBCHEM	58007373	C34H41Cl2N5O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZEYRMSIQYBSOGW-KBVCYFDGSA-N
29163	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9224	CID 70677271	MI-1061|4-((3'R,4'S,5'R)-6''-CHLORO-4'-(3-CHLORO-2-FLUOROPHENYL)-2''-OXODISPIRO[CYCLOHEXANE-1,2'-PYRROLIDINE-3',3''-INDOLINE]-5'-CARBOXAMIDO)BENZOIC ACID|HY-125858|CS-0102051|1410737-34-6|BDBM50041086	-	PUBCHEM	70677271	C30H26Cl2FN3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BIDSEXPFIMKDMF-LOLKONATSA-N
29164	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9225	BDBM50041085	-	-	CHEMBL	CHEMBL3355429	C28H30Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CQRICESTNDBKIY-KUGUZAOFSA-N
29165	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9226	CID 118720818	BDBM50041081	-	PUBCHEM	118720818	C27H30Cl2FN3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UKYBEEZQFSEMPW-LPJWUPNOSA-N
29166	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9227	BDBM50041075	-	-	CHEMBL	CHEMBL3355417	C30H34Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVWMOYGSAUBCGS-WPUIHRAISA-N
29167	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9228	BDBM50041074	-	-	CHEMBL	CHEMBL3355416	C29H32Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QQOSBFYZJBKRMS-UAKSBLKBSA-N
29168	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9229	BDBM50041073	-	-	CHEMBL	CHEMBL3355415	C28H30Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQXQIUHXDOQUSV-XLKFOPSHSA-N
29169	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9230	BDBM50041031	-	-	CHEMBL	CHEMBL3355411	C28H32Cl2FN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IRTYMVBGDAJRNN-XLKFOPSHSA-N
29170	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Aguilar A (2014)	25496041	224775	9231	CID 71023165	US8629141, 15|BDBM112748	-	PUBCHEM	71023165	C29H33Cl2FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZULOPCMLZWFEKU-ZLZBJJAKSA-N
29171	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Zhao Y (2015)	25396320	224776	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29172	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Rew Y (2014)	25384157	224777	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29173	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Rew Y (2014)	25384157	224777	9233	4-[[2-[(3R,5R,6S)-1-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetyl]amino]-2-methoxybenzoic acid	3UD|4WT2|US8952036, EX. 3|4-(2-((3R,5R,6S)-1-((S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL)-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETAMIDO)-2-METHOXYBENZOIC ACID|4-[[2-[(3R,5R,6S)-1-[(1S)-2-TERT-BUTYLSULFONYL-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETYL]AMINO]-2-METHOXYBENZOIC ACID|4-({[(3R,5R,6S)-1-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETYL}AMINO)-2-METHOXYBENZOIC ACID|Q27454148|BDBM144638	-	PUBCHEM	77108133	C37H41Cl2FN2O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGOICCMBEDDFCI-NXQGQTBASA-N
29203	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9251	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-morpholin-4-ylsulfonylethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-MORPHOLIN-4-YLSULFONYLETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053052	-	PUBCHEM	67999720	C29H34Cl2N2O6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSZIUWBZPLMUNE-GCMXZSHTSA-N
29204	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9252	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-piperidin-1-ylsulfonylethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-PIPERIDIN-1-YLSULFONYLETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053051	-	PUBCHEM	67998850	C30H36Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HLRWFQSMFDJFQQ-QXMDYEBFSA-N
29205	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9253	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(methylsulfamoyl)ethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(METHYLSULFAMOYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053045	-	PUBCHEM	68000050	C26H30Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TUDCVMKUXPXOII-HLMLHLEXSA-N
29206	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wang Y (2014)	25042256	224780	9254	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(propan-2-ylsulfamoyl)ethyl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PROPAN-2-YLSULFAMOYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|BDBM50053040	-	PUBCHEM	68000097	C28H34Cl2N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OLQSAQIIKIWIRZ-YWCVFVGNSA-N
29212	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9260	[(2R,3S)-2-(2-Hydroxyethyl)-3-[4-[2-(2-methoxyethoxy)phenyl]piperazine-1-carbonyl]-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020151	-	PUBCHEM	90644648	C35H39ClF6N4O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GAWXPLJRMGISPF-AAYBCKPTSA-N
29213	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9261	[(2R,3S)-2-(2,3-Dihydroxypropyl)-3-[4-[2-(2-methoxyethoxy)phenyl]piperazine-1-carbonyl]-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020150	-	PUBCHEM	90644647	C36H41ClF6N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLKVYUYEIZLSOY-QAJMXTGNSA-N
29214	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9262	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-propyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone;hydrochloride	BDBM50020149	-	PUBCHEM	90644646	C36H41ClF6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOTYTBNHWCLYIW-BRMBYNPVSA-N
29215	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Ma Y (2014)	24900882	224782	9263	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-prop-2-enyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone	BDBM50001929	-	PUBCHEM	23642310	C36H38F6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKOYVKQWXLFSPH-FJQKOURKSA-N
29216	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9264	2-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-5-methyl-1,3,4-oxadiazole	2-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-5-METHYL-1,3,4-OXADIAZOLE|BDBM50012598	-	PUBCHEM	67031670	C24H20Cl2F2N4O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WSYHJRPECYYALB-UHFFFAOYSA-N
29217	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9265	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazole-4-carboxamide	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOLE-4-CARBOXAMIDE|BDBM50012597	-	PUBCHEM	67032018	C22H19Cl2F2N3O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WCIBRTOQTDTZEH-UHFFFAOYSA-N
29218	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9266	1-(5-Chloro-2-methylphenyl)-5-(3-chlorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012596	-	PUBCHEM	67035866	C23H16Cl2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HGVSKSDYMUWDDZ-UHFFFAOYSA-N
29219	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9267	1-(5-Chloro-2-Methylphenyl)-5-(3-Chlorophenyl)-2-(3-Methylphenyl)-1h-Imidazole-4-Carboxylic Acid	1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-(3-METHYLPHENYL)IMIDAZOLE-4-CARBOXYLIC ACID|4OQ3|Q27453318|2V8|1-(5-CHLORO-2-METHYLPHENYL)-5-(3-CHLOROPHENYL)-2-(3-METHYLPHENYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012595	-	PUBCHEM	50996417	C24H18Cl2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UYJZPBBJELZWKZ-UHFFFAOYSA-N
29220	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9268	1-(3-Chloro-2-fluorophenyl)-5-(3-chlorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012594	-	PUBCHEM	67035746	C22H13Cl2FN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWKUHDIFHWGKSW-UHFFFAOYSA-N
29221	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9269	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-phenylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-PHENYLACETAMIDE|BDBM50012593	-	PUBCHEM	67954180	C31H26Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LVTCZQLXJGEKOF-UHFFFAOYSA-N
29222	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9270	5-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-1,3,4-oxadiazol-2-amine	5-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-1,3,4-OXADIAZOL-2-AMINE|BDBM50012592	-	PUBCHEM	67954546	C23H19Cl2F2N5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XPRXKGPGGKKGGT-UHFFFAOYSA-N
29223	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9271	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-methylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-METHYLACETAMIDE|2-{2-[4-(5-AMINO-[1,3,4]OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUORO-PHENYL)-2-CYCLOHEXYL-IMIDAZOL-1-YL]-4-CHLORO-3-FLUORO-PHENYL}-N-METHYL-ACETAMIDE|BDBM50012591	-	PUBCHEM	67032045	C26H24Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FXKYGUQUTHFCIZ-UHFFFAOYSA-N
29224	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9272	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012590	-	PUBCHEM	67954173	C22H18Cl2F2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OKZRWZNDCUYSPD-UHFFFAOYSA-N
29225	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9273	5-[1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-4-yl]-2H-tetrazole	5-[1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-4-YL]-2H-TETRAZOLE|BDBM50012589	-	PUBCHEM	67032499	C22H18Cl2F2N6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	APOKXFGOAIBPAE-UHFFFAOYSA-N
29226	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9274	1-(3-Chloro-2-fluorophenyl)-5-(3-chloro-4-fluorophenyl)-2-phenylimidazole-4-carboxylic acid	1-(3-CHLORO-2-FLUOROPHENYL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-PHENYLIMIDAZOLE-4-CARBOXYLIC ACID|BDBM50012588	-	PUBCHEM	67954174	C22H12Cl2F2N2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FQIJHXGZFVSBLN-UHFFFAOYSA-N
29227	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9275	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-tert-butylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-TERT-BUTYLACETAMIDE|BDBM50012587	-	PUBCHEM	60167943	C29H30Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZZSUOGVLVLJPR-UHFFFAOYSA-N
29228	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Vaupel A (2014)	24704029	224783	9276	2-[2-[4-(5-Amino-1,3,4-oxadiazol-2-yl)-5-(3-chloro-4-fluorophenyl)-2-cyclohexylimidazol-1-yl]-4-chloro-3-fluorophenyl]-N-cyclohexylacetamide	2-[2-[4-(5-AMINO-1,3,4-OXADIAZOL-2-YL)-5-(3-CHLORO-4-FLUOROPHENYL)-2-CYCLOHEXYLIMIDAZOL-1-YL]-4-CHLORO-3-FLUOROPHENYL]-N-CYCLOHEXYLACETAMIDE|BDBM50012586	-	PUBCHEM	67034825	C31H32Cl2F2N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SMUUKZTVPGSBEE-UHFFFAOYSA-N
29229	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Pan W (2014)	24656661	224784	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29230	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Pan W (2014)	24656661	224784	9263	[(2R,3S)-3-[4-[2-(2-Methoxyethoxy)phenyl]piperazine-1-carbonyl]-2-prop-2-enyl-3-[4-(trifluoromethyl)phenoxy]piperidin-1-yl]-[4-(trifluoromethyl)pyridin-3-yl]methanone	BDBM50001929	-	PUBCHEM	23642310	C36H38F6N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QKOYVKQWXLFSPH-FJQKOURKSA-N
29252	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Gonzalez AZ (2014)	24601644	224786	9297	2-[2-[[(3R,5R,6S)-1-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl]-1,3-thiazol-5-yl]acetic acid	(2-{[(3R,5R,6S)-1-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(4-CHLORO-3-FLUOROPHENYL)-5-(3-CHLOROPHENYL)-3-METHYL-2-OXOPIPERIDIN-3-YL]METHYL}-1,3-THIAZOL-5-YL)ACETIC ACID|Q27453278|AM-6761|2U0|4ODE|BDBM50008748	-	PUBCHEM	73386675	C33H37Cl2FN2O5S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNLHOKSDTBAERS-CWIPYCOQSA-N
29253	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Gonzalez AZ (2014)	24548297	224787	9298	2-[(2R,5R,6R)-4-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid	Q27453272|CS-0012311|AM-8735|[(2R,5R,6R)-4-[(1S)-2-(TERT-BUTYLSULFONYL)-1-CYCLOPROPYLETHYL]-6-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-3-OXOMORPHOLIN-2-YL]ACETIC ACID|4OBA|2TW|2-[(2R,5R,6R)-4-[(1S)-2-TERT-BUTYLSULFONYL-1-CYCLOPROPYLETHYL]-6-(3-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-3-OXOMORPHOLIN-2-YL]ACETIC ACID|HY-12734|BDBM50007638	-	PUBCHEM	71544420	C27H31Cl2NO6S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZTMSSDQFJNEUNG-WMMXXEOUSA-N
29254	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Sun D (2014)	24456472	224788	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29255	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Sun D (2014)	24456472	224788	9299	2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid	Q27451341|AM-8553|{(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(2S,3S)-2-HYDROXYPENTAN-3-YL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(2S,3S)-2-HYDROXYPENTAN-3-YL]-3-METHYL-2-OXOPIPERIDIN-3-YL]ACETIC ACID|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((2S,3S)-2-HYDROXYPENTAN-3-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|0R3|BDBM50388626	-	PUBCHEM	56965957	C25H29Cl2NO4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YUALYRLIFVPOHL-VPLUBSIMSA-N
29290	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wells JA (2007)	18075579	224792	8613	Nutlin-3	NUTLIN-3, (-)-|NUTLIN 3|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-[4-METHOXY-2-(PROPAN-2-YLOXY)PHENYL]-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|EX-A1359|CC-452|(-)-NUTLIN-3|NUTLIN3A|Q27166862|SB19406|HMS3649P17|C30H30CL2N4O4|AS-75148|1960AH|RAC-4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NUTLIN (3A)|BCP9001003|(RAC)-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL)(PIPERAZIN-1-YL)METHANONE|S8059|ZINC16051336|4-((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|4-[(4S,5R)-4,5-BIS-(4-CHLORO-PHENYL)-2-(2-ISOPROPOXY-4-METHOXY-PHENYL)-4,5-DIHYDRO-IMIDAZOLE-1-CARBONYL]-PIPERAZIN-2-ONE|NUTLIN-3A CHIRAL|(4S,5R)-NUTLIN-3|2-PIPERAZINONE, 4-(((4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-(4-METHOXY-2-(1-METHYLETHOXY)PHENYL)-1H-IMIDAZOL-1-YL)CARBONYL)-|4HG7|2603AH|A11501|4-[[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-4,5-DIHYDRO-2-[4-METHOXY-2-(1-METHYLETHOXY)PHENYL]-1H-IMIDAZOL-1-YL]CARBONYL]-2-PIPERAZINONE|SR-01000946691|W-5585|NUTLIN 3A|675576-98-4|UNII-53IA0V845C COMPONENT BDUHCSBCVGXTJM-WUFINQPMSA-N|NUTLIN-3A, >=98% (HPLC)|4-(4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4, 5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-2-ONE|NCGC00344347-05|NUTLIN-3A|SC-95163|UNII-L7C92IOE65|AKOS027422740|4J3E|4-[(4S,5R)-4,5-BIS(4-CHLOROPHENYL)-2-(4-METHOXY-2-PROPAN-2-YLOXYPHENYL)-4,5-DIHYDROIMIDAZOLE-1-CARBONYL]PIPERAZIN-2-ONE|HY-10029|CS-0296|SR-01000946691-1|NUTLIN-3A (CHIRAL)|L7C92IOE65|BDBM50229787	-	CHEMSPIDER	187530	C30H30Cl2N4O4	small molecule	-	548472-68-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BDUHCSBCVGXTJM-UHFFFAOYSA-N
29291	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Wells JA (2007)	18075579	224792	9309	DI-Chloro-benzo-diazepine	BENZODIAZEPINEDIONE, 1|(2S)-(4-CHLOROPHENYL)[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ETHANOIC ACID|BMCL163310 COMPOUND 1|Q27459367|TDP-222669|(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|DIZ|(2S)-2-(4-CHLOROPHENYL)-2-[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,3-DIHYDRO-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|1T4E|JNJ-38732382|DI-CHLORO-BENZO-DIAZEPINE|BDBM31285	-	PUBCHEM	656933	C23H15Cl2IN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQEQUYKKMMKSSX-PMACEKPBSA-N
29300	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	unknown	target	Grasberger BL (2005)	15715460	224796	9309	DI-Chloro-benzo-diazepine	BENZODIAZEPINEDIONE, 1|(2S)-(4-CHLOROPHENYL)[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ETHANOIC ACID|BMCL163310 COMPOUND 1|Q27459367|TDP-222669|(4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|DIZ|(2S)-2-(4-CHLOROPHENYL)-2-[(3S)-3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,3-DIHYDRO-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID|1T4E|JNJ-38732382|DI-CHLORO-BENZO-DIAZEPINE|BDBM31285	-	PUBCHEM	656933	C23H15Cl2IN2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQEQUYKKMMKSSX-PMACEKPBSA-N
29306	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	unknown	target	He Y (2017)	28135237	224799	9322	A-395	(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine|2089148-72-9|GTPL9525|HY-101512|CS-0021615|J3.609.234C|(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]pyrrolidin-3-amine|rel-(3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine|rac-(3R,4S)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine (4)|BDBM223987|BDBM50241662	-	PUBCHEM	123132213	C26H35FN4O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CMZCLMBPMLFJJU-YVEFUNNKSA-N
29307	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	unknown	target	Qi W (2017)	28135235	224800	9323	N-(Furan-2-Ylmethyl)-8-(4-Methylsulfonylphenyl)-[1,2,4]triazolo[4,3-C]pyrimidin-5-Amine	KS-00000U9I|N-(FURAN-2-YLMETHYL)-8-(4-(METHYLSULFONYL)PHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|S8496|AK684382|CS-6391|N-[(FURAN-2-YL)METHYL]-8-(4-METHANESULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|EX-A1724|AS-74203|N-(FURAN-2-YLMETHYL)-8-(4-METHYLSULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE|EED-226|AKOS030632048|2083627-02-3|AC-29879|BCP19849|CCG-268284|MAK683(EED226/COMPOUND 43)|J3.609.221A|SB40406|ACN-051243|EED226|HY-101117|BDBM225230	-	PUBCHEM	123132228	C17H15N5O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DYIRSNMPIZZNBK-UHFFFAOYSA-N
29834	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Cao K (2020)	32211658	226774	9929	Cisplatin	transplatin|cis-platin|cis-Diamminedichlorplatine|Dichloroplatinum diammoniate|cis-Diamineplatinum(II) dichloride|MFCD00011623|TP2450000|UNII:Q20Q21Q62J|TP2455000|Cisplatin impurity A	-	CHEMSPIDER	76401	H6Cl2N2Pt	small molecule	-	14913-33-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LXZZYRPGZAFOLE-UHFFFAOYSA-L
29836	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Ishizawa J (2018)	29490944	228642	9913	DS-3032B	-	-	CHEMSPIDER	71060369	C37H44Cl2FN5O8S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WPJOGWGXMTUHPW-CIPNXXNHSA-N
29837	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Holzer P (2015)	26181851	224770	9193	Nvp-cgm097	ZINC253387855|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-[METHYL-[[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-7-PROPAN-2-YLOXY-1,4-DIHYDROISOQUINOLIN-3-ONE|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-[METHYL[4-(4-METHYL-3-OXOPIPERAZIN-1-YL)-TRANS-CYCLOHEXYLMETHYL]AMINO]PHENYL)-1,4-DIHYDRO-2H-ISOQUINOLIN-3-ONE|4UF6MSL0ZH|NVP-CGM-097|KS-00000TSY|CCG-270337|US9051279, 106|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-[4-(METHYL{[TRANS-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL}AMINO)PHENYL]-7-(PROPAN-2-YLOXY)-1,4-DIHYDROISOQUINOLIN-3(2H)-ONE|EX-A1059|CS-3138|HY-15954|NVP-CGM097 (CGM-097)|NVP-CGM097|Q27454942|NCGC00390552-01|W5747|4T4|NVP CGM097|(1S)-1-(4-CHLOROPHENYL)-6-METHOXY-2-{4-[METHYL({[(1R,4R)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL]METHYL})AMINO]PHENYL}-7-(PROPAN-2-YLOXY)-1,2,3,4-TETRAHYDROISOQUINOLIN-3-ONE|C38H47CLN4O4|1313363-54-0|(1S)-1-(4-CHLOROPHENYL)-1,4-DIHYDRO-6-METHOXY-7-(1-METHYLETHOXY)-2-[4-[METHYL[[TRANS-4-(4-METHYL-3-OXO-1-PIPERAZINYL)CYCLOHEXYL]METHYL]AMINO]PHENYL]-3(2H)-ISOQUINOLINONE|CGM-097|(S)-1-(4-CHLOROPHENYL)-7-ISOPROPOXY-6-METHOXY-2-(4-(METHYL(((1R,4S)-4-(4-METHYL-3-OXOPIPERAZIN-1-YL)CYCLOHEXYL)METHYL)AMINO)PHENYL)-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE|UNII-4UF6MSL0ZH|A16326|AS-75288|S7875|CGM097|J3.509.326E|CGM 097|BCP18308|AKOS030526402|BDBM162123	-	PUBCHEM	53240420	C38H47ClN4O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CLRSLRWKONPSRQ-CPOWQTMSSA-N
29838	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Furet P (2016)	27542305	228643	9857	Siremadlin	-	-	CHEMSPIDER	27542305	C11H6F3N3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NJLJARSIRPKVMU-UHFFFAOYSA-N
29839	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Sun D (2014)	24456472	224788	9232	Mdm2 inhibitor amg-232	AC-29027|1352066-68-2|ZINC103248035|COMPOUND 2 [PMID: 24456472]|SB17210|AMG 232|GTPL11133|C28H35CL2NO5S|HY-12296|2-((3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-((S)-1-(ISOPROPYLSULFONYL)-3-METHYLBUTAN-2-YL)-3-METHYL-2-OXOPIPERIDIN-3-YL)ACETIC ACID|KRT232|V2654|MDM2 INHIBITOR AMG-232|2-[(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-[(2S)-3-METHYL-1-PROPAN-2-YLSULFONYLBUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID|AMG232|AOB87308|3-IPERIDINEACETIC ACID, 5-(3-HLOROPHENYL)-6-(4-HLOROPHENYL)-3-ETHYL-1-(1S)-2-ETHYL-1-[(1-ETHYLETHYL)ULFONYL]ETHYL]ROPYL]-2-XO-, (3R,5R,6S)-|AMG-232|UNII-7R7G6EH5UL|CS-3282|DB15299|(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3-METHYL-1-((1S)-2-METHYL-1-(((1-METHYLETHYL)SULFONYL)METHYL)PROPYL)-2-OXO-3-PIPERIDINEACETIC ACID|NCGC00387801-04|AS-17007|NCGC00387801-05|KRT-232|1447813-21-9|7R7G6EH5UL|BDBM50448947	-	PUBCHEM	58573469	C28H35Cl2NO5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DRLCSJFKKILATL-YWCVFVGNSA-N
29840	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Yi H (2018)	29716622	228645	9893	APG-115	-	-	CHEMSPIDER	64853887	C34H38Cl2FN3O4	small molecule	-	1818393-16-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YJCZPJQGFSSFOL-MNZPCBJKSA-N
29936	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Vu B (2013)	24900694	228678	8379	RG7112	RO-5045337|Q8MI0X869M|{(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}{4-[3-(methylsulfonyl)propyl]-1-piperazinyl}methanone|Methanone, [(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl][4-[3-(methylsulfonyl)propyl]-1-piperazinyl]-	-	CHEMSPIDER	28189760	C38H48Cl2N4O4S	small molecule	-	939981-39-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBGKPEROWUKSBK-QPPIDDCLSA-N
29940	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Reed D (2010)	20080970	228679	9926	SJ 172550	SJ 172550|MFCD03142926|SJ-172550|2-[2-Chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-acetic acid methyl ester|Methyl {2-chloro-6-ethoxy-4-[(Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]phenoxy}acetate|Acetic acid, 2-[2-chloro-4-[(Z)-(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-, methyl ester	-	CHEMSPIDER	1104430	C22H21ClN2O5	small molecule	-	431979-47-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RKKFQJXGAQWHBZ-YVLHZVERSA-N
29941	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Gu L (2016)	27666947	228680	9898	MX69	Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-|4-{8-[(3,4-Dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl}benzoic acid	-	CHEMSPIDER	3290554	C27H26N2O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XCBONKHCCRJMNW-UHFFFAOYSA-N
29944	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Zhang Z (2014)	24997575	228681	9839	RO8994	RO8994|Spiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-2-oxo-, (2'S,3R,4'S,5'R)-|(2'S,3R,4'S,5'R)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide	-	CHEMSPIDER	31135025	C31H31Cl2FN4O4	small molecule	-	1309684-94-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MURAVORBGFDSMA-ISKXDESKSA-N
29945	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Karan G (2016)	26883273	228682	9865	Ctx1	9-Acridinecarbonitrile, 3,6-diamino-|3,6-Diamino-9-acridinecarbonitrile	-	CHEMSPIDER	384728	C14H10N4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PUMGFEMNXBLDKD-UHFFFAOYSA-N
29946	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Huang Y (2014)	24405416	228683	9841	YH239-EE	1H-Indole-2-carboxylic acid, 6-chloro-3-[1-[[(4-chlorophenyl)methyl]formylamino]-2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-, ethyl ester|Ethyl 6-chloro-3-{1-[(4-chlorobenzyl)(formyl)amino]-2-[(2-methyl-2-propanyl)amino]-2-oxoethyl}-1H-indole-2-carboxylate|YH239-EE|YH 239-EE	-	CHEMSPIDER	31042602	C25H27Cl2N3O4	small molecule	-	1364488-67-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTUBDDRFPQLPKD-UHFFFAOYSA-N
29947	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Porter JR (2010)	20856941	228684	9838	BH3I-1	BH3I-1|MFCD03453544|5-(p-Bromobenzylidine)-alpha-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic acid|3-Thiazolidineacetic acid, 5-[(4-bromophenyl)methylene]-alpha-(1-methylethyl)-4-oxo-2-thioxo-, (5E)-|2-[(5E)-5-(4-Bromobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-methylbutanoic acid	-	CHEMSPIDER	23291035	C15H14BrNO3S2	small molecule	-	300817-68-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	COHIEJLWRGREHV-YRNVUSSQSA-N
29948	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Chen R (2017)	28581721	228685	9751	Bivalent ligand 197	CG428|Bivalent_ligand_197	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	-	-	-	-	-	-	-	-	-	-
29949	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Gollner A (2016)	27775892	228686	9872	BI-0252	Benzoic acid, 4-[(3S,3'S,3a'S,5'R,6a'S)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-1,2,3',3'a,4',5',6',6'a-octahydro-2-oxospiro[3H-indole-3,2'(1'H)-pyrrolo[3,2-b]pyrrol]-5'-yl]-|4-[(3S,3'S,3a'S,5'R,6a'S)-6-Chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1,2,3',3a',4',5',6',6a'-octahydro-1'H-spiro[indole-3,2'-pyrrolo[3,2-b]pyrrol]-5'-yl]benzoic acid	-	CHEMSPIDER	59053072	C30H26Cl2FN3O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CCPUFNJKOGKOOG-AFKAWQRRSA-N
29953	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Wang W (2018)	30217928	228687	9860	MA242	Acetic acid, 2,2,2-trifluoro-, compd. with 7-[[(4-chlorophenyl)methyl]amino]-3,4-dihydro-1-[(4-methylphenyl)sulfonyl]pyrrolo[4,3,2-de]quinolin-8(1H)-one (1:1)|7-[(4-Chlorobenzyl)amino]-1-[(4-methylphenyl)sulfonyl]-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one trifluoroacetate (1:1)	-	CHEMSPIDER	75533946	C26H21ClF3N3O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YTSFRIUMZUCDMV-UHFFFAOYSA-N
29954	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Graves B (2012)	22745160	216713	9905	RO-5963	2-{(4E)-4-[(6-Chloro-7-methyl-1H-indol-3-yl)methylene]-2,5-dioxo-1-imidazolidinyl}-2-(3,4-difluorophenyl)-N-(1,3-dihydroxy-2-propanyl)acetamide|1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-alpha-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo-, (4E)-	-	CHEMSPIDER	75533987	C24H21ClF2N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZFYQBPVMECJUBO-FBCYGCLPSA-N
29955	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Graves B (2012)	22745160	216713	9905	RO-5963	2-{(4E)-4-[(6-Chloro-7-methyl-1H-indol-3-yl)methylene]-2,5-dioxo-1-imidazolidinyl}-2-(3,4-difluorophenyl)-N-(1,3-dihydroxy-2-propanyl)acetamide|1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-alpha-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo-, (4E)-	-	CHEMSPIDER	75533987	C24H21ClF2N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZFYQBPVMECJUBO-FBCYGCLPSA-N
29956	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Chen R (2017)	28581721	228685	9921	2-[4-({(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}carbonyl)-1-piperazinyl]-1-(4-morpholinyl)ethanone dihydrochloride	2-[4-({(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[2-ethoxy-4-(2-methyl-2-propanyl)phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl}carbonyl)-1-piperazinyl]-1-(4-morpholinyl)ethanone dihydrochloride|Ethanone, 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)-, hydrochloride (1:2)	-	CHEMSPIDER	35308372	C40H51Cl4N5O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSDSITOZGWIHGA-IBBBAUQKSA-N
29993	115301	9978	RP11-554C12.1	RBX1	BA554C12.1|RNF75|ROC1	9606	Homo sapiens	inhibitor	target	Yu Q (2020)	32145688	226735	9858	Gossypol	N,N,1,3-Tetramethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine|1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N,N,1,3-tetramethyl-|Dipotassium Salt|Sodium Salt|BL193|ssypol|AT101|TASH1|POGOSIN	-	CHEMSPIDER	32145688	C30H30O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBKSWRVVCFFDOT-UHFFFAOYSA-N
30069	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- RPS6KA1:TAE684)	-
30079	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- RPS6KA1:ceritinib)	-
30149	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EED: EED ligand)	-
30151	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EED: EED ligand)	-
30153	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EZH2: EED ligand)	-
30155	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EZH2: EED ligand)	-
30157	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- SUZ12: EED ligand)	-
30159	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- SUZ12: EED ligand)	-
30187	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30189	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30299	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	target	Li Y (2019)	30525597	223612	9809	Bivalent ligand 246	MD-222|Bivalent_ligand_246	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MD-222 (CRBN:lenalidomide --- MDM2:MI-1061)	-
30372	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	inhibitor	target	Pairawan S (2021)	33663585	228644	9937	ALRN-6924	CS-0044703	-	PUBCHEM	381833444	-	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	-
30373	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	inhibitor	target	Pairawan S (2021)	33663585	228644	9937	ALRN-6924	CS-0044703	-	PUBCHEM	381833444	-	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	-
30574	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK2:TAE684)	-
30576	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK4:TAE684)	-
30580	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK6:TAE684)	-
30628	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30648	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PRKAA1:TAE684)	-
30650	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PRKAA2:TAE684)	-
30660	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KA1:TAE684)	-
30740	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK2:TAE684)	-
30742	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK4:TAE684)	-
30746	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK6:TAE684)	-
30790	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30806	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PRKAA1:TAE684)	-
30812	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- RPS6KA1:TAE684)	-
30848	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CDK4:GNF-7)	-
30890	111586	5600	-	MAPK11	P38B|P38BETA2|PRKM11|SAPK2|SAPK2B|p38-2|p38Beta	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK11:GNF-7)	-
30894	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
30896	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
30898	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
30900	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPKAPK2:GNF-7)	-
30916	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- RPS6KA3:GNF-7)	-
30956	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK2:TAE)	-
30958	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK4:TAE)	-
30960	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDk6:TAE)	-
30966	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CHEK1:TAE)	-
30990	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAPK7:TAE)	-
31000	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PRKAA1:TAE)	-
31034	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31054	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31056	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31068	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PRKAA1:Ceritinib)	-
31070	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PRKAA2:Ceritinib)	-
31076	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
31078	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
31088	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- TBK1:Ceritinib)	-
31106	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- CDK4:GNF-7)	-
31130	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK14:GNF-7)	-
31132	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK8:GNF-7)	-
31134	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK9:GNF-7)	-
31136	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPKAPK2:GNF-7)	-
31146	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- RPS6KA1:GNF-7)	-
31148	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- RPS6KA3:GNF-7)	-
31178	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK2:Rebastinib)	-
31180	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK4:Rebastinib)	-
31184	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK6:Rebastinib)	-
31206	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- PRKAA1:Rebastinib)	-
31208	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- RPS6KA1:Rebastinib)	-
31238	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK6:Ponatinib)	-
31268	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAPK14:Ponatinib)	-
31296	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- CDK4:GNF-7)	-
31322	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK14:GNF-7)	-
31324	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK7:GNF-7)	-
31326	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK9:GNF-7)	-
31328	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31330	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31338	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31358	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- CDK4:GNF-7)	-
31380	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK14:GNF-7)	-
31382	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK7:GNF-7)	-
31384	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK8:GNF-7)	-
31386	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK9:GNF-7)	-
31388	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31390	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31400	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31402	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA3:GNF-7)	-
31428	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31448	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31450	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31454	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- PRKAA1:Ceritinib)	-
31456	111550	5563	-	PRKAA2	AMPK|AMPK2|AMPKa2|PRKAA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- PRKAA2:Ceritinib)	-
31460	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
31462	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
31482	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK4:AT7519)	-
31486	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CHEK1:AT7519)	-
31530	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK2:Thienopyrimidines)	-
31532	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK4:Thienopyrimidines)	-
31534	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK6:Thienopyrimidines)	-
31546	114120	8550	-	MAPKAPK5	MAPKAP-K5|MK-5|MK5|PRAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MAPKAPK5:Thienopyrimidines)	-
31586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK2:TAE684)	-
31588	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK4:TAE684)	-
31592	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK6:TAE684)	-
31608	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- PRKAA1:TAE684)	-
31612	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- RPS6KA1:TAE684)	-
31628	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
31630	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
31644	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK8:Thienopyrimidines)	-
31646	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK9:Thienopyrimidines)	-
31666	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10070	Bivalent Ligand 280	DD-02-198|Bivalent_Ligand_280	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-02-198 (VHL:VH032---MAPK14:AZ628)	-
31672	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide---CDK4:TAE684)	-
31682	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK6:TAE684)	-
31690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK2:TAE684)	-
31706	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- PRKAA1:TAE684)	-
31724	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK2:Dabrafenib)	-
31728	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK4:Dabrafenib)	-
31730	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK6:Dabrafenib)	-
31778	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- MAPK14:PP58 (kinobeads) 212391-57-6)	-
31806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK2:TAE684)	-
31808	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK4:TAE684)	-
31812	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK6:TAE684)	-
31832	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide---CDK4:GNF-7)	-
31854	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
31856	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide---a MAPK9:GNF-7)	-
31868	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- CDK4:GNF-7)	-
31880	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
31882	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
31942	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK2:Ceritinib)	-
31944	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK4:Ceritinib)	-
31948	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK6:Ceritinib)	-
31954	111588	5602	RP13-514E23.1	MAPK10	JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK10:Ceritinib)	-
31956	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK8:Ceritinib)	-
31958	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK9:Ceritinib)	-
31960	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- RPS6KA1:Ceritinib)	-
31972	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK2:TAE684)	-
31992	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide---CDK4:Dinaciclib)	-
32062	119075	50488	-	MINK1	B55|MAP4K6|MINK|YSK2|ZC3|hMINK|hMINKbeta	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- MINK1:not specified)	-
32084	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
32086	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
32136	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
32140	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
32142	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
32146	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- RPS6KA1:Ceritinib)	-
32148	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- RPS6KA3:Ceritinib)	-
32238	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- MAPK14:Quizartinib)	-
32284	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- CDK4:GNF-7)	-
32304	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- MAPK7:PND-1186)	-
32308	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- RPS6KA1:PND-1186)	-
32310	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- RPS6KA3:PND-1186)	-
32318	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK4:Palbociclib)	-
32320	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32338	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- CDK6:kinobeads)	-
32368	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- RPS6KA1:PND-1186)	-
32370	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- RPS6KA3:PND-1186)	-
32378	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK4:Ribociclib)	-
32380	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK6:Ribociclib)	-
32422	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- CDK4:Ipatasertib)	-
32428	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide---CDK4:Ponatininb)	-
32434	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- MAPK14:Ponatininb)	-
32480	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-204 (CRBN:thalidomide---CDK4:Palbociclib)	-
32482	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- CDK6:Palbociclib)	-
32510	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32512	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32548	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10117	Bivalent Ligand 330	TL13-112|Bivalent_Ligand_330	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-112 (CRBN:pomalidomide---RPS6KA1:TAE684)	-
32550	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32552	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK6:Palbociclib)	-
32560	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	degradation	target	Yan S (2021)	34093856	232273	10110	Bivalent ligand 334	dCeMM4|Bivalent_ligand_334	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Nano-MP@PSI (VHL:Nano-MP@PSI---MDMX:Nano-MP@PSI)	-
32562	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Qu X (2021)	33773286	232265	10113	Bivalent Ligand 335	Bivalent_Ligand_335	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS125 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32564	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Qu X (2021)	33773286	232265	10112	Bivalent Ligand 336	Bivalent_Ligand_336	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS126 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32582	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	degradation	target	Zhang C (2021)	34927316	232727	10096	Bivalent Ligand 342	SPNCOX|Bivalent_Ligand_342	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SPNCOX (VHL:GSGSALAPYIP---PTGS2:indomethacin)	-
32588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32594	111902	5970	-	RELA	NFKB3|p65	9606	Homo sapiens	degradation	target	Liu J (2021)	34100597	232747	10100	Bivalent Ligand 346	Bivalent_Ligand_346	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NF-kB-PROTAC (dNF-kB)(VHL:VHLL-X-BCN---RELA:N3-ODN)	-
32596	108201	1869	-	E2F1	E2F-1|RBAP1|RBBP3|RBP3	9606	Homo sapiens	degradation	target	Liu J (2021)	34100597	232747	10101	Bivalent Ligand 347	Bivalent_Ligand_347	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E2F-PROTAC (dE2F) (VHL:VHLL-X-BCN---E2F1:N3-ODN)	-
32638	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	He K (2020)	32317208	235047	10049	Bivalent Ligand 363	PROTAC 16c|Bivalent_Ligand_363	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 16c (CRBN:lenalidomide---EGFR:osimertinib)	-
32720	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
32722	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
32726	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
32750	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Wang J (2022)	35210568	236436	9999	Bivalent ligand 384	MS177|Bivalent_ligand_384	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS177 (CRBN:pomalidomide --- EZH2:C24)	-
32752	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EZH2:EED226)	-
32754	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EED:EED226)	-
32756	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- SUZ12:EED226)	-
32781	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	He S (2021)	34221872	233411	10146	Bivalent ligand 393	PROTAC 11a-1|Bivalent_ligand_393	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 11a-1 (MDM2:Nutlin-3 derivative compound 2 --- MDM2:Nutlin-3 derivative compound 2)	-
32800	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10125	Bivalent ligand 402	R0/ctx|Bivalent_ligand_402	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/ctx (RNF43:RNF43 ab, R0 clone --- EGFR:cetuximab)	-
32802	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10124	Bivalent ligand 403	R0/matu|Bivalent_ligand_403	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/matu (RNF43:RNF43 ab, R0 clone --- EGFR:matuzumab)	-
32804	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10127	Bivalent ligand 404	R0/neci|Bivalent_ligand_404	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/neci (RNF43:RNF43 ab, R0 clone --- EGFR:necitumumab)	-
32806	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10126	Bivalent ligand 405	R0/pani|Bivalent_ligand_405	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/pani (RNF43:RNF43 ab, R0 clone --- EGFR:panitumumab)	-
32808	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10129	Bivalent ligand 406	R3/ctx|Bivalent_ligand_406	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R3/ctx  (RNF43:RNF43 ab, R3 clone --- EGFR:cetuximab)	-
32812	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10131	Bivalent ligand 408	Z18/ctx|Bivalent_ligand_408	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Z18/ctx (ZNRF3:Z18 --- EGFR:cetuximab)	-
32889	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Roeth S (2020)	32668202	242881	10369	Bivalent ligand 437	VHL-aHRAS AdPROM|Bivalent_ligand_437	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: VHL-aHRAS AdPROM (VHL --- HRAS:aHRAS)	-
32893	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- HRAS:iDAB RAS)	-
32899	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- HRAS:iDAB RAS)	-
32925	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Lim S (2021)	33655066	242886	10408	Bivalent ligand 449	K27-SPOP|Bivalent_ligand_449	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: K27-SPOP (SPOP --- HRAS:DARPin K27)	-
32939	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK6:palbociclib)	-
32941	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10377	Bivalent ligand 456	SAB355|Bivalent_ligand_456	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB355 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32943	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10382	Bivalent ligand 457	CST837|Bivalent_ligand_457	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CST837 (CRBN:thalidomide --- CDK6:palbociclib)	-
32945	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32947	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK4:palbociclib)	-
32957	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10361	Bivalent ligand 459	PROTAC 34|Bivalent_ligand_459	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 34 (VHL:modified VH298 --- CDK6:palbociclib)	-
32959	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32961	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10418	Bivalent ligand 460	PROTAC 11|Bivalent_ligand_460	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 11 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32963	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK6:palbociclib)	-
32965	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK4:palbociclib)	-
32967	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK4:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK4:palbociclib)	-
32969	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK6:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK6:palbociclib)	-
32991	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao M (2021)	33676183	232098	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CC-885 (CRBN:CC-885 --- CDK4:CC-885)	-
33021	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10410	Bivalent ligand 473	p53-DUBTACs #6|Bivalent_ligand_473	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: p53-DUBTACs #6 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33023	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10428	Bivalent ligand 474	p53-DUBTACs #7|Bivalent_ligand_474	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: p53-DUBTACs #7 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33025	109869	3661	-	IRF3	-	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10417	Bivalent ligand 475	IRF-DUBTAC #7|Bivalent_ligand_475	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: IRF-DUBTAC #7 (OTUB1:DUBL-X-BCN --- IRF3:N3-IRF3-ODN)	-
33045	108202	1870	-	E2F2	E2F-2	9606	Homo sapiens	degradation	target	Liu TT (2022)	36375317	244515	10412	Bivalent ligand 482	bufalin|Bivalent_ligand_482	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: bufalin (ZFP91:bufalin---E2F2:bufalin)	-
33087	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation 	target	Zhang X (2020)	32171162	246256	10352	Bivalent ligand 503	14o|Bivalent_ligand_503	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 14o (VHL:VHL ligand --- EGFRL858R/T790M:XTF-262)	-
33161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Raymonda MH (2022)	34871905	239614	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: p38 MAPK inhibitor; viral inhibition mechanism undetermined	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
33188	107027	545	-	ATR	FCTCS|FRP1|MEC1|SCKL|SCKL1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10213	berzosertib	VE-822|UNII:L423PRV3V3|VX-970|Berzosertib|L423PRV3V3|5-[4-(Isopropylsulfonyl)phenyl]-3-(3-{4-[(methylamino)methyl]phenyl}-1,2-oxazol-5-yl)-2-pyrazinamine|2-Pyrazinamine, 3-[3-[4-[(methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-	-	CHEMSPIDER	30773968	C24H25N5O3S	small molecule	-	1232416-25-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: ATR inhibitor (PMID: 31018854); viral inhibition mechanism undetermined	JZCWLJDSIRUGIN-UHFFFAOYSA-N
33197	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10202	Torin 2	Torin 2|9-(6-AMINOPYRIDIN-3-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H,2H-BENZO[H]1,6-NAPHTHYRIDIN-2-ONE|Benzo[h][1,6]naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-|9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one	-	CHEMSPIDER	26232176	C24H15F3N4O	small molecule	-	1223001-51-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor (PMID: 26239364); viral inhibition mechanism undetermined	GUXXEUUYCAYESJ-UHFFFAOYSA-N
33198	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10207	vistusertib	AZD-2014|AZD 2014|vistusertib	-	CHEMSPIDER	28294977	C25H30N6O3	small molecule	-	1009298-59-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor (PMID: 27031247); viral inhibition mechanism undetermined	JUSFANSTBFGBAF-IRXDYDNUSA-N
33199	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10258	dactolisib	BEZ-235|2-Methyl-2-{4-[3-methyl-2-oxo-8-(3-quinolinyl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile|Benzeneacetonitrile, 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alpha-dimethyl-|NVP-BEZ 235|NVP-BEZ235|BEZ 235|NVP-BEZ235-NX|BEZ235|Dactolisib|NVPBEZ235|NVP BEZ235	-	CHEMSPIDER	10151099	C30H23N5O	small molecule	-	915019-65-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor; viral inhibition mechanism undetermined	JOGKUKXHTYWRGZ-UHFFFAOYSA-N
33269	111595	5609	-	MAP2K7	JNKK2|MAPKK7|MEK|MEK 7|MKK7|PRKMK7|SAPKK-4|SAPKK4	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Huntington KE (2022)	35631444	232850	10165	VS-6766	CH5126766|D0D4252V97|Ro-5126766 Free Base|Ro 5126766|N-(3-Fluoro-4-{[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-chromen-3-yl]methyl}-2-pyridinyl)-N'-methylsulfuric diamide|Sulfamide, N-[3-fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N'-methyl-	-	CHEMSPIDER	17623621	C21H18FN5O5S	small molecule	-	946128-88-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: Integrin inhibitor; viral inhibition mechanism undetermined	LMMJFBMMJUMSJS-UHFFFAOYSA-N
33281	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Yamamoto M (2021)	888800000485	232833	7270	CTS-1027	4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL]-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE|193022-04-7|RS-130830|Ro-1130830	-	DRUGBANK	DB08490	C19H20ClNO6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:MMP13 inhibitor; exact viral inhibition mechanism undetermined but authors show disruption of the metalloproteinase pathway is involved	ROSNVSQTEGHUKU-UHFFFAOYSA-N
33294	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	activator/sars-cov-2 inhibitor	target	Parthasarathy H (2023)	36417940	246230	323	Metformin	Metformine|Metformine pamoate|Haurymellin|1,1-Dimethylbiguanide|Metformina|N,N-Dimethylimidodicarbonimidic diamide|Metforminum|Metformin|Dimethylbiguanid	apo-metformin 850 mg tablets|g	DRUGBANK	DB00331	C4H11N5	small molecule	A10BD03|A10BD05|A10BD11|A10BD10|A10BD02|A10BD13|A10BD14|A10BD15|A10BD16|A10BD17|A10BD18|A10BD07|A10BD08|A10BA02|A10BD20	657-24-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:AMPK activator; viral inhibition mechanism undetermined	XZWYZXLIPXDOLR-UHFFFAOYSA-N
33360	112550	6667	-	SP1	-	9606	Homo sapiens	sars-cov-2 inhibitor	target	Han H (2024)	38375778	241442	5643	Plicamycin	Mithramycine|Mithracin|Mithramycinum|Plicamycine|Plicamycin|Plicamycinum|Mithramycin|Aureolic acid	-	DRUGBANK	DB06810	C52H76O24	small molecule	L01DC02	18378-89-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: SP1 inhibitor, mechanism undetermined; antiviral activity in cells and hamsters	CFCUWKMKBJTWLW-BKHRDMLASA-N
33449	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10330	4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole	SW218141-2|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE;SB-203580|SR-01000597367|J-008891|HMS3267B07|BCP01763|CDMGBJANTYXAIV-UHFFFAOYSA-N|RWJ-64809|US9187470, 104 (SB203580)|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]- & Z-100|4-[5-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-3H-IMIDAZOL-4-YL]PYRIDINE|OU13V1EYWQ|SB 203580|AKOS015994568|HMS1792H05|AM81234|4-{4-(4-FLUOROPHENYL)-2-[4-(METHANESULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|PB-203580|UNII-OU13V1EYWQ|HMS3403H05|RAC-4-(5-(4-FLUOROPHENYL)-2-(4-((R)- METHANESULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|NCGC00025035-04|PB203580|HMS3676M17|CCG-206878|BIO1_000745|4-{4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|HB1302|NCGC00025035-05|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE|S1076|F0864|HMS3244I16|BIO1_000256|NCGC00025035-02|A15256|NCGC00025035-01|J-513573|RWJ 64809|K00038|PYRIDINE, 4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)-|ES-0013|NSC-755772|PYRIDINE, 4-[4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL]-|TOCRIS-1402|4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|4-[4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|PYRIDINE, 4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)-|SB203580|4-[4-(4-FLUOROPHENYL)-2-(4-METHANESULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|BIRB-203580|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|HMS3295M11|NSC755772|BRD-A37704979-003-01-2|SB 203580, SOLID, >=98% (HPLC)|SB 203580 & Z-100|SR-01000597367-1|CBIOL_001970|ADEZMAPIMOD|NCGC00381704-12|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]-|KINOME_2521|4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE|ADEZMAPIMOD [INN]|SMR004701767|1PME|TOCRIS-1202|SB16633|MLS006010840|HMS3244I15|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)-PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|AC-32046|BIO1_001234|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)1H-IMIDAZOLE|EX-A134|GTPL5269|NCGC00025035-03|SB-203580|DTXSID2040577|CS-0140|152121-47-6|PB 203580|FT-0674525|BIRB203580|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|HMS3412M17|CID_176155|F17411|HMS3654M15|SB 203580 - CAS 152121-47-6|SB203580,RWJ 64809,PB 203580|BRD-A37704979-001-02-4|Q7389023|C21H16FN3OS|BCPP000074|RWJ64809|HMS3244J15|MFCD00922198|HMS1990H05|HY-10256|AKOS005145971|HMS3229O04|BSPBIO_001104	-	PUBCHEM	176155	C21H16FN3OS	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human p38 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	CDMGBJANTYXAIV-UHFFFAOYSA-N
33453	111586	5600	-	MAPK11	P38B|P38BETA2|PRKM11|SAPK2|SAPK2B|p38-2|p38Beta	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10333	Ralimetinib	5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL)-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO(4,5-B)PYRIDIN-2-YLAMINE|UNII-73I34XW4HD|SB16635|NCGC00346537-01|XPPBBJCBDOEXDN-UHFFFAOYSA-N|NSC-766820|LSN-2322600 FREE BASE|BCPP000180|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|RALIMETINIB [USAN]|Q27088512|862505-00-8|RALIMETINIB [INN]|LY 2228820|RALIMETINIB [USAN:INN]|LY2228820 FREE BASE|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|862505-00-8 (FREE BASE)|RALIMETINIB [WHO-DD]|NCGC00346537-05|LY22288220|DB11787|AKOS027282678|HMS3674E21|3H-IMIDAZO(4,5-B)PYRIDIN-2-AMINE, 5-(2-(1,1-DIMETHYLETHYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-|GTPL7959|3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,5-[2-(1,1-DIMETHYLETHYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)-|CS-0008496|D10658|RALIMETINIB (USAN/INN)|(5P)-5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|DTXSID00235456|HY-13241A|BCP02033|LY-2228820|73I34XW4HD|RALIMETINIB ( LY2228820)|NSC766820|NCGC00346537-03|E98891|RALIMETINIB|YXT|5-(2-(TERT-BUTYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|LSN2322600 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-YLAMINE|LY-2228820 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUOROPHENYL)-3H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[5,4-B]PYRIDIN-2-AMINE|NSC785335|NSC-785335|BCP9000871|FT-0727743	-	PUBCHEM	11539025	C24H29FN6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK11/MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	XPPBBJCBDOEXDN-UHFFFAOYSA-N
33454	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10333	Ralimetinib	5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL)-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO(4,5-B)PYRIDIN-2-YLAMINE|UNII-73I34XW4HD|SB16635|NCGC00346537-01|XPPBBJCBDOEXDN-UHFFFAOYSA-N|NSC-766820|LSN-2322600 FREE BASE|BCPP000180|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|RALIMETINIB [USAN]|Q27088512|862505-00-8|RALIMETINIB [INN]|LY 2228820|RALIMETINIB [USAN:INN]|LY2228820 FREE BASE|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|862505-00-8 (FREE BASE)|RALIMETINIB [WHO-DD]|NCGC00346537-05|LY22288220|DB11787|AKOS027282678|HMS3674E21|3H-IMIDAZO(4,5-B)PYRIDIN-2-AMINE, 5-(2-(1,1-DIMETHYLETHYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-|GTPL7959|3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,5-[2-(1,1-DIMETHYLETHYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)-|CS-0008496|D10658|RALIMETINIB (USAN/INN)|(5P)-5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|DTXSID00235456|HY-13241A|BCP02033|LY-2228820|73I34XW4HD|RALIMETINIB ( LY2228820)|NSC766820|NCGC00346537-03|E98891|RALIMETINIB|YXT|5-(2-(TERT-BUTYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|LSN2322600 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-YLAMINE|LY-2228820 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUOROPHENYL)-3H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[5,4-B]PYRIDIN-2-AMINE|NSC785335|NSC-785335|BCP9000871|FT-0727743	-	PUBCHEM	11539025	C24H29FN6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK11/MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	XPPBBJCBDOEXDN-UHFFFAOYSA-N
33456	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10335	p38alpha Inhibitor 1	5-(2,4-DIFLUOROPHENOXY)-N-(2-(DIMETHYLAMINO)ETHYL)-1-ISOBUTYL-1H-INDAZOLE-6-CARBOXAMIDE|ARRY-797|1034189-82-6|CS-0085271|P38?? INHIBITOR 1|EX-A3148|ARRY-371797|ARRY371797|1036404-17-7|COMPOUND 7 [PMID: 19950901]|ARRY797|P38A INHIBITOR 1|P38 ALPHA INHIBITOR 1|P38-ALPHA- INHIBITOR 1|-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|P38ALPHA INHIBITOR 1|HY-114423|AKOS040733949|ARRY-797; ARRY-371797|P38|A INHIBITOR 1|MS-27245|5-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|GTPL11095	-	PUBCHEM	46883775	C22H26F2N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	IFGWYHGYNVGVRB-UHFFFAOYSA-N
33457	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10176	dinaciclib	Dinaciclib|SCH 727965|SCH727965|2-[(2S)-1-(3-Ethyl-7-{[(1-oxido-3-pyridinyl)methyl]amino}pyrazolo[1,5-a]pyrimidin-5-yl)-2-piperidinyl]ethanol|4V8ECV0NBQ|2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-	-	CHEMSPIDER	25027387	C21H28N6O2	small molecule	-	779353-01-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human CDK2/5/9 inhibitor;  antiviral activity against SARS-CoV-2 in VERO-E6 and ACE2-A549 cells	PIMQWRZWLQKKBJ-SFHVURJKSA-N
33511	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Thomas E (2023)	36831540	248703	10744	Bivalent ligand 514	VNPP433-3b|bivalent_ligand_514	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: VNPP433-3 (MDM2:VNPP433-3 --- AR/AR-V7: VNPP433-3)	-
33586	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	De Dominici M (2020)	32040545	256620	10765	Bivalent ligand 536	YX-2-107|bivalent_ligand_536	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YX-2-107 (CRBN:thalidomide --- CDK6:palbociclib)	-
33587	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK6:palbociclib)	-
33589	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK4:palbociclib)	-
33598	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK6:palbociclib)	-
33600	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK4:palbociclib)	-
33602	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK6:ribociclib)	-
33604	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK4:ribociclib)	-
33622	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK4:palbociclib)	-
33624	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK6:palbociclib)	-
33652	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2021)	34788776	254514	10794	Bivalent ligand 565	ha-PROTAC 13|bivalent_ligand_565	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 13 (CRBN:lenalidomide --- EGFRDel19:HALG-gefitinib 4-anilinoquinazoline core)	-
33654	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2021)	34788776	254514	10795	Bivalent ligand 566	PROTAC 11|bivalent_ligand_566	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 11 (CRBN:lenalidomide --- EGFRDel19:gefitinib 4-anilinoquinazoline core)	-
33674	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	degradation	target	Wu Y (2022)	35755293	256634	10805	Bivalent ligand 576	PROTAC A7|bivalent_ligand_576	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC A7 (VHL:VHL-1 --- NAMPT:MS7)	-
33716	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK4:Palbociclib)	-
33718	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK6:Palbociclib)	-
33728	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Pan P (2023)	37751283	254536	10822	Bivalent ligand 601	PPM-3|bivalent_ligand_601	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PPM-3 (VHL:VH032 --- ERK5:XMD8-92)	-
33729	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10823	Bivalent ligand 602	22-SLF|bivalent_ligand_602	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: 22-SLF (FBXO22:22 --- FKBP12:SLF)	-
33731	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10824	Bivalent ligand 603	22a-SLF|bivalent_ligand_603	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108570	2280	RP11-314N13.2	FKBP1A	FKBP-12|FKBP-1A|FKBP1|FKBP12|PKC12|PKCI2|PPIASE	9606	Homo sapiens	target	Standardized BVL Name: 22-SLF (FBXO22:22a --- FKBP12:SLF)	-
33733	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10825	Bivalent ligand 604	22-JQ1|bivalent_ligand_604	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: 22-JQ1 (FBXO22:22 --- BRD4:JQ1)	-
33735	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	degradation	recruited e3 ligase	Basu AA (2024)	38965383	254538	10826	Bivalent ligand 605	22-TAE|bivalent_ligand_605	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: 22-TAE (FBXO22:22 --- ALK:TAE)	-
33774	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK4:palbociclib)	-
33776	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK6:palbociclib)	-
33778	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10846	Bivalent ligand 625	FN-POM|bivalent_ligand_625	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FN-POM (CRBN:pomalidomide --- CDK2:N-1501)	-
33791	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37572533	254628	10852	Bivalent ligand 631	E-3P-MDM2|bivalent_ligand_631	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: E-3P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33793	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37572533	254628	10853	Bivalent ligand 632	E-4P-MDM2|bivalent_ligand_632	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: E-4P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33860	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	degradation	target	Zhang P (2023)	37369332	254853	10878	Bivalent ligand 657	compound C5|bivalent_ligand_657	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound C5 (VHL:VHL ligand 2 --- NAMPT:FK866)	-
33864	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Ody BK (2023)	37625128	254777	10880	Bivalent ligand 659	HaloPROTAC-4b|bivalent_ligand_659	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-4b (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33866	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Ody BK (2023)	37625128	254777	10881	Bivalent ligand 660	HaloPROTAC-5c|bivalent_ligand_660	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-5c (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33868	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Ody BK (2023)	37625128	254777	10882	Bivalent ligand 661	HaloPROTAC-3|bivalent_ligand_661	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-3 (VHL:degradation moiety B --- EGFR:EGFP-HaloTag2)	-
33880	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10888	Bivalent ligand 667	18|bivalent_ligand_667	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 18 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33882	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10889	Bivalent ligand 668	19|bivalent_ligand_668	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 19 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33926	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Wang L (2021)	33664520	256648	10909	Bivalent ligand 688	CPS2|bivalent_ligand_688	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CPS2 (CRBN:pomalidomide --- CDK2:J2)	-
33928	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Jin J (2022)	36509291	256649	10910	Bivalent ligand 689	TSM-1|bivalent_ligand_689	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TSM-1 (CRBN:lenalidomide --- STAT3:Toosendanin)	-
33942	110428	4282	-	MIF	GIF|GLIF|MMIF	9606	Homo sapiens	degradation	target	Xiao Z (2021)	34018657	255460	10917	Bivalent ligand 696	MD13|bivalent_ligand_696	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MD13 (CRBN:pomalidomide --- MIF:Compound 3 (MIF tautomerase inhibitor))	-
33948	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Zhou H (2021)	34141084	255462	10919	Bivalent ligand 698	SD-91|bivalent_ligand_698	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SD-91 (CRBN:lenalidomide --- STAT3:SI-191)	-
33950	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Zhang H (2022)	35178183	255463	10920	Bivalent ligand 699	Compound 6h|bivalent_ligand_699	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 6h (VHL:VHL ligand --- EGFR Del19/T790M/C797S:brigatinib analog 3)	-
33964	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	target	Wang B (2021)	33862513	232662	10928	Bivalent ligand 707	WB214|bivalent_ligand_707	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WB214 (CRBN:lenalidomide --- MDM2:MDM2 Ugi ligand 1)	-
33982	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Hati S (2021)	34560429	255476	10936	Bivalent ligand 715	PROTAC-8|bivalent_ligand_715	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC-8 (VHL:VH032 --- CDK2:AZD5438)	-
34000	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Li N (2025)	40045307	256655	10942	Bivalent ligand 721	KT-333|bivalent_ligand_721	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KT-333 (VHL:VHL ligand --- STAT3:undisclosed)	-
34008	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	degradation	target	Zhou P (2024)	39267779	256658	10946	Bivalent ligand 725	V5|bivalent_ligand_725	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	109703	3482	-	IGF2R	CD222|CIMPR|M6P-R|MPR1|MPRI	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: V5 (IGF2R:M6PR-A --- VEGF:VEGF-A2)	-
34024	111181	5155	LL22NC03-10C3.2	PDGFB	IBGC5|PDGF-2|PDGF2|SIS|SSV|c-sis	9606	Homo sapiens	degradation	target	Wu Y (2023)	36722696	256661	10952	Bivalent ligand 731	GalNAc-AptPDGF|bivalent_ligand_731	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	106924	432	-	ASGR1	ASGPR|ASGPR1|CLEC4H1|HL-1	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: GalNAc-AptPDGF (ASGR1:tri-GalNAc --- PDGFB:AptPDGF)	-
34054	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Hu J (2020)	33284613	256664	10961	Bivalent ligand 740	MS928|bivalent_ligand_740	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS928 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34058	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Hu J (2020)	33284613	256664	10962	Bivalent ligand 741	MS934|bivalent_ligand_741	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS934 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34062	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Hu J (2020)	33284613	256664	10963	Bivalent ligand 742	MS910|bivalent_ligand_742	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS910 (CRBN:pomalidomide --- MAP2K1:PD0325901)	-
34066	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- EZH2:EPZ6438)	-
34068	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- EED:EPZ6438)	-
34070	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- SUZ12:EPZ6438)	-
34072	111863	5928	-	RBBP4	NURF55|RBAP48|lin-53	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- RBBP4:EPZ6438)	-
34088	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EED:EED226)	-
34090	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EZH2:EED226)	-
34092	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---SUZ12:EED226)	-
34094	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EED:EED226)	-
34096	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EZH2:EED226)	-
34098	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---SUZ12:EED226)	-
34100	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Bashore FM (2023)	36877831	256669	10974	Bivalent ligand 753	UNC7698|bivalent_ligand_753	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC7698 (VHL:VH032-amine ---EED:EED226)	-
34120	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK4:YHJ1039)	-
34122	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK6:YHJ1039)	-
34132	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK4:Palbociclib)	-
34134	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK6:Palbociclib)	-
34164	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	degradation	target	Zhu Z (2023)	37183204	256444	10992	Bivalent ligand 771	UNC9036|bivalent_ligand_771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC9036 (VHL:VH032 --- STING:diABZI compound 3)	-
34166	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	degradation	target	Zhu Z (2023)	37183204	256444	10993	Bivalent ligand 772	UNC8899|bivalent_ligand_772	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC8899 (VHL:VH032 --- STING:diABZI compound 3)	-
34168	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	degradation	target	Zhu Z (2023)	37183204	256444	10994	Bivalent ligand 773	UNC8900|bivalent_ligand_773	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UNC8900 (VHL:VH032 --- STING:diABZI compound 3)	-
34173	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Cui J (2023)	37175323	256446	10996	Bivalent ligand 775	XR-4|bivalent_ligand_775	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	target	Standardized BVL Name: XR-4 (MDM2:Compound 2 (spiroindolinone pyrrolidinecarboxamide Nutlin-3 derivative) --- MDM2:Compound 2 (spiroindolinone pyrrolidinecarboxamide Nutlin-3 derivative))	-
34228	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Son SH (2023)	36968534	256474	11017	Bivalent ligand 796	PRZ-18002|bivalent_ligand_796	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PRZ-18002 (CRBN:pomalidomide --- MAPK14:p-p38 ligand)	-
34237	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	degradation	recruited e3 ligase	Chang M (2022)	36910255	256500	11022	Bivalent ligand 800	BMM4|bivalent_ligand_800	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: BMM4 (MDM2:Nutlin-3 --- BCL-XL:ABT-263)	-
34240	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2023)	36906965	256503	11023	Bivalent ligand 801	ha-PROTAC 9|bivalent_ligand_801	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 9 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34242	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2023)	36906965	256503	11024	Bivalent ligand 802	ha-PROTAC 10|bivalent_ligand_802	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 10 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34262	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Cubillos-Rojas M (2023)	36765568	256520	11032	Bivalent ligand 810	NR-11c|bivalent_ligand_810	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-11c (VHL:VHL ligand --- MAPK14:PH-797804)	-
34272	111972	6045	GS1-120K12.1	RNF2	BAP-1|BAP1|DING|HIPI3|RING1B|RING2	9606	Homo sapiens	degradation	target	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS147 (VHL:VHL1 --- RING1B:EED226)	-
34274	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	degradation	target	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS147 (VHL:VHL1 --- EED:EED226)	-
