#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
15	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Viloria-Petit A (2001)	11431346	171748	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
17	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Hosokawa N (1999)	10480573	171746	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
18	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Wakita H (1999)	10601294	171747	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
19	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Suwa T (2000)	10628369	171745	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
20	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Burke P (2001)	11408594	141935	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer|Ctuximab|Cetuximab|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
362	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
363	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	30	Insulin Human	Insulin human, rDNA origin|Regular Insulin, human|Insulin Human Regular|Insulin human regular (rDNA)|Human insulin|Insulin (human)|Insulin, human|Insulin human|Insulin regular|Insulin recombinant human|human insulin (rDNA)|Insulin human [rDNA origin]|Insulin recombinant purified human|High molecular weight insulin human	humulin r u-500 kwikpen|humuli	DRUGBANK	DB00030	C257H383N65O77S6	biologic	-	11061-68-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
464	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	unknown	target	Mummery CL (1993)	7680555	171953	38	Palifermin	FGF-7|KGF|HBGF-7|Keratinocyte growth factor precursor|Fibroblast growth factor- 7	kepivance	DRUGBANK	DB00039	C721H1142N202O204S9	biologic	V03AF08	162394-19-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
465	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	unknown	target	Cancilla B (2001)	11422746	171957	38	Palifermin	FGF-7|KGF|HBGF-7|Keratinocyte growth factor precursor|Fibroblast growth factor- 7	kepivance	DRUGBANK	DB00039	C721H1142N202O204S9	biologic	V03AF08	162394-19-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
466	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	unknown	target	Beer HD (2000)	10821861	171956	38	Palifermin	FGF-7|KGF|HBGF-7|Keratinocyte growth factor precursor|Fibroblast growth factor- 7	kepivance	DRUGBANK	DB00039	C721H1142N202O204S9	biologic	V03AF08	162394-19-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
467	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	unknown	target	Yamanaka T (2000)	11149756	171955	38	Palifermin	FGF-7|KGF|HBGF-7|Keratinocyte growth factor precursor|Fibroblast growth factor- 7	kepivance	DRUGBANK	DB00039	C721H1142N202O204S9	biologic	V03AF08	162394-19-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
468	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	unknown	target	Launay C (1994)	7890137	171954	38	Palifermin	FGF-7|KGF|HBGF-7|Keratinocyte growth factor precursor|Fibroblast growth factor- 7	kepivance	DRUGBANK	DB00039	C721H1142N202O204S9	biologic	V03AF08	162394-19-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
812	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1998)	9850732	172163	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
813	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (2001)	11327694	172166	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
814	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Locci P (1995)	7648625	172165	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
815	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1997)	9435505	172164	69	Hyaluronidase	Hyaluronidase PH-20|Hyaluronidase (sheep testis isoenzyme)|Ovine hyaluronidase|Sperm surface protein PH-20|Hyaluronidase (ovine)|HYAL-1|Hyaluronidase, ovine|Hyaluronidase (glycoprotein, sheep testis isoenzyme)|Hyaluronidase 1 precursor|Sperm adhesion molecule 1	wydase injection liq 150 units	DRUGBANK	DB00070	C2455H3775N617O704S21	biologic	B06AA03	488712-31-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
839	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
840	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
841	111860	5925	RP11-174I10.1	RB1	OSRC|PPP1R130|RB|p105-Rb|pRb|pp110	9606	Homo sapiens	unknown	target	Biener Y (1990)	1701386	172180	70	Insulin Pork	Insulin (pork)|Insulin, regular, pork|Insulin purified porcine|Porcine insulin|Insulin purified pork|Insulin, porcine|Insulin porcine	-	DRUGBANK	DB00071	C257H387N65O76S6	biologic	A10AE03|A10AD03|A10AC03|A10AB03	12584-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
893	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	71	Trastuzumab	Anti HER2|Ig gamma-1 chain C region	herceptin|perjeta-herceptin	DRUGBANK	DB00072	C6470H10012N1726O2013S42	biologic	L01XC03	180288-69-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1387	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1388	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gerber HP (2005)	15705858	172458	107	Bevacizumab	antiVEGF|Avastin	avastin	DRUGBANK	DB00112	C6538H10034N1716O2033S44	biologic	L01XC07	216974-75-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1914	120060	54583	PNAS-118	EGLN1	C1orf12|ECYT3|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1915	120060	54583	PNAS-118	EGLN1	C1orf12|ECYT3|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
3075	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3076	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3077	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	unknown	target	Grant GA (1989)	2692566	173667	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3078	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	unknown	target	Goldsmith LA (1976)	945314	173666	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3079	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	unknown	target	Grant GA (2002)	12183470	173668	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3261	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	O'Brien J (2006)	17006762	173739	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3262	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Draghia AC (2007)	17308685	173740	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3263	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Semenza GL (2007)	17555402	73182	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3588	111507	5515	-	PPP2CA	PP2Ac|PP2CA|PP2Calpha|RP-C	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	157	Vitamin E	(R,R,R)--tocopherol|(2R,4'R,8'R)--tocopherol|(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL|5,7,8-trimethyltocol|d--tocopherol|alpha-tocopherol|(+)--tocopherol	maltlevol liq|mnps formula sup	DRUGBANK	DB00163	C29H50O2	small molecule	-	59-02-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVJHHUAWPYXKBD-IEOSBIPESA-N
3589	111507	5515	-	PPP2CA	PP2Ac|PP2CA|PP2Calpha|RP-C	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	157	Vitamin E	(R,R,R)--tocopherol|(2R,4'R,8'R)--tocopherol|(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL|5,7,8-trimethyltocol|d--tocopherol|alpha-tocopherol|(+)--tocopherol	maltlevol liq|mnps formula sup	DRUGBANK	DB00163	C29H50O2	small molecule	-	59-02-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVJHHUAWPYXKBD-IEOSBIPESA-N
3718	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3719	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3727	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	unknown	target	Van Meter TE (2006)	17041888	174029	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
4079	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Ulus IH (2000)	10799660	174228	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4080	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Kilpatrick IC (2001)	11673765	174229	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4081	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Rothman RB (1999)	10231134	174226	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4082	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Nandigama RK (2002)	11911838	174227	184	Phentermine	Phenterminum|Fentermina|alpha,alpha-Dimethylphenethylamine	phentermine resin er|lomaira|f	DRUGBANK	DB00191	C10H15N	small molecule	A08AA01	122-09-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHHVAGZRUROJKS-UHFFFAOYSA-N
4158	110831	4758	DAAP-222I20.1	NEU1	NANH|NEU|SIAL1	9606	Homo sapiens	inhibitor	target	Chavas LM (2010)	20222714	174303	191	Oseltamivir	Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate|1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-|osltamivir|Oseltamivirum|()-oseltamivir|Oseltamivir	nat-oseltamivir|tamiflu oral s	DRUGBANK	DB00198	C16H28N2O4	small molecule	J05AH02	196618-13-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSZGPKBBMSAYNT-RRFJBIMHSA-N
4254	111309	5291	-	PIK3CB	P110BETA|PI3K|PI3KBETA|PIK3C1	9606	Homo sapiens	unknown	target	Foukas LC (2002)	12145276	174346	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4258	111577	5591	-	PRKDC	DNA-PKcs|DNAPK|DNPK1|HYRC|HYRC1|IMD26|XRCC7|p350	9606	Homo sapiens	unknown	target	Foukas LC (2002)	12145276	174346	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4259	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	unknown	target	Foukas LC (2002)	12145276	174346	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4261	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Blasina A (1999)	10531013	174349	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4262	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Sarkaria JN (1999)	10485486	174348	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4561	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4562	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Bantel H (2000)	11151876	174545	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4563	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	226	Aminosalicylic Acid	PAS|4-amino-2-hydroxybenzoic acid|para-amino salicylic acid|p-aminosalicylic acid|4-aminosalicylic acid|para-aminosalicylic acid|4-aminosalicylate	paser|nemasol sodium tab 500mg	DRUGBANK	DB00233	C7H7NO3	small molecule	J04AA03|J04AA02|J04AA01	65-49-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUBBRNOQWQTFEX-UHFFFAOYSA-N
4701	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4702	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Bantel H (2000)	11151876	174545	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4703	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4704	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4705	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Bantel H (2000)	11151876	174545	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4706	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	237	Mesalazine	Pentasa|m-Aminosalicylic acid|Mesasal|5-ASA|Mesalazina|Canasa|Mesalazinum|Mesalamine|Mesalazine|P-Aminosalicylsaeure|Asacolitin|Rowasa|Fisalamine|Claversal|Asacol|Salofalk|Iialda|5-aminosalicylic acid|3-carboxy-4-hydroxyaniline|Lixacol	asacol 800|pentasa|pentasa sup	DRUGBANK	DB00244	C7H7NO3	small molecule	A07EC02	89-57-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBOPZPXVLCULAV-UHFFFAOYSA-N
4870	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4871	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Baron S (2007)	17317669	116189	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4872	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Hart SA (2007)	17314305	174699	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4873	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kwok KC (2010)	20387803	174698	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4874	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Dixon A (2007)	17308373	174697	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4875	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Bains M (2007)	17320868	174696	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4876	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Munoz G (2007)	17306201	174695	248	Diethylstilbestrol	trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol|4,4'-Dihydroxy-alpha,beta-diethylstilbene|,'-diethyl-(E)-4,4'-stilbenediol|trans-Diethylstilbesterol|Diethylstilbestrol|Stilboestrol|(E)-3,4-bis(4-hydroxyphenyl)-3-hexene|4,4'-dihydroxy-,-diethylstilbene|DES|(e)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol|Dietilestilbestrol|trans-Diethylstilboesterol|Diethylstilbestrolum|Distilbene|trans-Diethylstilbestrol|alpha,Alpha'-diethyl-(e)-4,4'-stilbenediol	stilbestrol 1.0mg tablet|stilb	DRUGBANK	DB00255	C18H20O2	small molecule	G03CB02|L02AA04|G03CC05|L02AA01	56-53-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGLYKWWBQGJZGM-ISLYRVAYSA-N
4967	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Jordan VC (1983)	6872937	174767	262	Chlorotrianisene	Chlortrianizen|Chlortrianisestrol|Chloortrianisestrol|Chlorotrianizen|Chlortrianisoestrolum|Clorotrianiseno|Chlorotrianisenum|Chlorestrolo|Chlorotrianisine|Chlortrianisen	-	DRUGBANK	DB00269	C23H21ClO3	small molecule	G03CA06	569-57-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPSDSIWYFKGBC-UHFFFAOYSA-N
4968	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Wang JY (2006)	17236558	174766	262	Chlorotrianisene	Chlortrianizen|Chlortrianisestrol|Chloortrianisestrol|Chlorotrianizen|Chlortrianisoestrolum|Clorotrianiseno|Chlorotrianisenum|Chlorestrolo|Chlorotrianisine|Chlortrianisen	-	DRUGBANK	DB00269	C23H21ClO3	small molecule	G03CA06	569-57-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPSDSIWYFKGBC-UHFFFAOYSA-N
4969	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	262	Chlorotrianisene	Chlortrianizen|Chlortrianisestrol|Chloortrianisestrol|Chlorotrianizen|Chlortrianisoestrolum|Clorotrianiseno|Chlorotrianisenum|Chlorestrolo|Chlorotrianisine|Chlortrianisen	-	DRUGBANK	DB00269	C23H21ClO3	small molecule	G03CA06	569-57-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPSDSIWYFKGBC-UHFFFAOYSA-N
4970	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kupfer D (1990)	2307235	174768	262	Chlorotrianisene	Chlortrianizen|Chlortrianisestrol|Chloortrianisestrol|Chlorotrianizen|Chlortrianisoestrolum|Clorotrianiseno|Chlorotrianisenum|Chlorestrolo|Chlorotrianisine|Chlortrianisen	-	DRUGBANK	DB00269	C23H21ClO3	small molecule	G03CA06	569-57-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPSDSIWYFKGBC-UHFFFAOYSA-N
5089	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Sakaguchi M (2006)	16551906	174881	274	Lidocaine	2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide|alpha-diethylamino-2,6-dimethylacetanilide|Lignocaine|2-(Diethylamino)-2',6'-acetoxylidide|-diethylamino-2,6-dimethylacetanilide	scar zone burn gel|sting relie	DRUGBANK	DB00281	C14H22N2O	small molecule	C05AD01|N01BB52|D04AB01|C01BB01|N01BB02|R02AD02|S01HA07|S02DA01	137-58-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NNJVILVZKWQKPM-UHFFFAOYSA-N
5154	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Stroud FC (2006)	16884174	174936	279	Conjugated Equine Estrogens	Estrogens, Conjugated|conjugated estrogens	apo-conest tab 0.3mg|premphase	DRUGBANK	DB00286	C18H21NaO5S	small molecule	G03CA57|G03CC07	438-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VUCAHVBMSFIGAI-ZFINNJDLSA-M
5155	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Smith MR (2006)	16985877	174937	279	Conjugated Equine Estrogens	Estrogens, Conjugated|conjugated estrogens	apo-conest tab 0.3mg|premphase	DRUGBANK	DB00286	C18H21NaO5S	small molecule	G03CA57|G03CC07	438-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VUCAHVBMSFIGAI-ZFINNJDLSA-M
5156	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Hou NN (2006)	16955786	174940	279	Conjugated Equine Estrogens	Estrogens, Conjugated|conjugated estrogens	apo-conest tab 0.3mg|premphase	DRUGBANK	DB00286	C18H21NaO5S	small molecule	G03CA57|G03CC07	438-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VUCAHVBMSFIGAI-ZFINNJDLSA-M
5157	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Gouva L (2006)	16982590	174938	279	Conjugated Equine Estrogens	Estrogens, Conjugated|conjugated estrogens	apo-conest tab 0.3mg|premphase	DRUGBANK	DB00286	C18H21NaO5S	small molecule	G03CA57|G03CC07	438-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VUCAHVBMSFIGAI-ZFINNJDLSA-M
5158	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Ropero AB (2006)	16876190	174939	279	Conjugated Equine Estrogens	Estrogens, Conjugated|conjugated estrogens	apo-conest tab 0.3mg|premphase	DRUGBANK	DB00286	C18H21NaO5S	small molecule	G03CA57|G03CC07	438-67-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VUCAHVBMSFIGAI-ZFINNJDLSA-M
5168	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	281	Amcinonide	Triamcinolonacetatcyclopentanonid|Amcinonidum|Amcinonida	cyclocort ont 0.1%|taro-amcino	DRUGBANK	DB00288	C28H35FO7	small molecule	D07AC11	51022-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ILKJAFIWWBXGDU-MOGDOJJUSA-N
5169	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Serres M (1994)	7981624	174978	281	Amcinonide	Triamcinolonacetatcyclopentanonid|Amcinonidum|Amcinonida	cyclocort ont 0.1%|taro-amcino	DRUGBANK	DB00288	C28H35FO7	small molecule	D07AC11	51022-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ILKJAFIWWBXGDU-MOGDOJJUSA-N
5170	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	281	Amcinonide	Triamcinolonacetatcyclopentanonid|Amcinonidum|Amcinonida	cyclocort ont 0.1%|taro-amcino	DRUGBANK	DB00288	C28H35FO7	small molecule	D07AC11	51022-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ILKJAFIWWBXGDU-MOGDOJJUSA-N
5216	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	287	Etonogestrel	Etonogestrelum|3-Ketodesogestrel|Implanon|3-Oxodesogestrel	nexplanon|implanon|nuvaring	DRUGBANK	DB00294	C22H28O2	small molecule	G03AC08	54048-10-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GCKFUYQCUCGESZ-BPIQYHPVSA-N
5217	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	287	Etonogestrel	Etonogestrelum|3-Ketodesogestrel|Implanon|3-Oxodesogestrel	nexplanon|implanon|nuvaring	DRUGBANK	DB00294	C22H28O2	small molecule	G03AC08	54048-10-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GCKFUYQCUCGESZ-BPIQYHPVSA-N
5272	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Juchem M (1990)	2175153	175067	297	Desogestrel	Cerazette|Desogestrelum|13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol	freya 21|linessa 28|apri|lines	DRUGBANK	DB00304	C22H30O	small molecule	G03AA09|G03FB10|G03AC09|G03AB05	54024-22-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPLCPCMSCLEKRS-BPIQYHPVSA-N
5273	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Fuhrmann U (1995)	7750284	175066	297	Desogestrel	Cerazette|Desogestrelum|13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol	freya 21|linessa 28|apri|lines	DRUGBANK	DB00304	C22H30O	small molecule	G03AA09|G03FB10|G03AC09|G03AB05	54024-22-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPLCPCMSCLEKRS-BPIQYHPVSA-N
5274	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Rabe T (2000)	10836199	175065	297	Desogestrel	Cerazette|Desogestrelum|13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol	freya 21|linessa 28|apri|lines	DRUGBANK	DB00304	C22H30O	small molecule	G03AA09|G03FB10|G03AC09|G03AB05	54024-22-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPLCPCMSCLEKRS-BPIQYHPVSA-N
5481	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Nicholson RI (2001)	11566608	175152	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5482	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Albanell J (2001)	11522647	175151	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5483	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Arteaga CL (2001)	11673690	175150	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5484	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5485	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Ciardiello F (2000)	10815932	175148	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5486	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Moasser MM (2001)	11585753	175149	310	Gefitinib	N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine|Gefitinib|ZD 1839|4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline|Iressa	iressa	DRUGBANK	DB00317	C22H24ClFN4O3	small molecule	L01XE02	184475-35-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XGALLCVXEZPNRQ-UHFFFAOYSA-N
5759	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	potentiator	target	Reitamo S (2002)	12113647	175334	329	Pimecrolimus	Pimecrolimusum|Pimecrolimus|33-Epi-chloro-33-desoxyascomycin	elidel	DRUGBANK	DB00337	C43H68ClNO11	small molecule	D11AH02	137071-32-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KASDHRXLYQOAKZ-XDSKOBMDSA-N
6033	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Vereide AB (2006)	16325240	175553	359	Levonorgestrel	13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one|Lvonorgestrel|17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol|Postinor|Levonorgestrelum|13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one|13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one|(-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one|18-Methyl-17-alpha-ethynyl-19-nortestosterone|Levonova|(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one|NorLevo|Jadelle|17alpha-Ethynyl-18-homo-19-nortestosterone|17-alpha-Ethynyl-13-ethyl-19-nortestosterone|d(-)-Norgestrel|17-Ethynyl-18-methyl-19-nortestosterone|Microval|Levonorgestrel|Mirena|17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one|Levonelle|18-Methylnorethisterone|Microlut|17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one|Plan b|Microluton	option 2|levonest|sronyx|lillo	DRUGBANK	DB00367	C21H28O2	small molecule	G03AB03|G03FA11|G03AA07|G03AD01|G03AC03|G03FB09	797-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYNJERNGUHSAO-XUDSTZEESA-N
6034	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Mirkin S (2005)	16084894	175552	359	Levonorgestrel	13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one|Lvonorgestrel|17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol|Postinor|Levonorgestrelum|13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one|13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one|(-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one|18-Methyl-17-alpha-ethynyl-19-nortestosterone|Levonova|(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one|NorLevo|Jadelle|17alpha-Ethynyl-18-homo-19-nortestosterone|17-alpha-Ethynyl-13-ethyl-19-nortestosterone|d(-)-Norgestrel|17-Ethynyl-18-methyl-19-nortestosterone|Microval|Levonorgestrel|Mirena|17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one|Levonelle|18-Methylnorethisterone|Microlut|17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one|Plan b|Microluton	option 2|levonest|sronyx|lillo	DRUGBANK	DB00367	C21H28O2	small molecule	G03AB03|G03FA11|G03AA07|G03AD01|G03AC03|G03FB09	797-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYNJERNGUHSAO-XUDSTZEESA-N
6035	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Vijayanathan V (2006)	16609013	175551	359	Levonorgestrel	13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one|Lvonorgestrel|17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol|Postinor|Levonorgestrelum|13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one|13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one|(-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one|18-Methyl-17-alpha-ethynyl-19-nortestosterone|Levonova|(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one|NorLevo|Jadelle|17alpha-Ethynyl-18-homo-19-nortestosterone|17-alpha-Ethynyl-13-ethyl-19-nortestosterone|d(-)-Norgestrel|17-Ethynyl-18-methyl-19-nortestosterone|Microval|Levonorgestrel|Mirena|17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one|Levonelle|18-Methylnorethisterone|Microlut|17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one|Plan b|Microluton	option 2|levonest|sronyx|lillo	DRUGBANK	DB00367	C21H28O2	small molecule	G03AB03|G03FA11|G03AA07|G03AD01|G03AC03|G03FB09	797-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYNJERNGUHSAO-XUDSTZEESA-N
6036	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Sun D (2007)	17634204	175555	359	Levonorgestrel	13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one|Lvonorgestrel|17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol|Postinor|Levonorgestrelum|13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one|13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one|(-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one|18-Methyl-17-alpha-ethynyl-19-nortestosterone|Levonova|(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one|NorLevo|Jadelle|17alpha-Ethynyl-18-homo-19-nortestosterone|17-alpha-Ethynyl-13-ethyl-19-nortestosterone|d(-)-Norgestrel|17-Ethynyl-18-methyl-19-nortestosterone|Microval|Levonorgestrel|Mirena|17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one|Levonelle|18-Methylnorethisterone|Microlut|17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one|Plan b|Microluton	option 2|levonest|sronyx|lillo	DRUGBANK	DB00367	C21H28O2	small molecule	G03AB03|G03FA11|G03AA07|G03AD01|G03AC03|G03FB09	797-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYNJERNGUHSAO-XUDSTZEESA-N
6037	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Abdel-Aleem H (2005)	16307966	175554	359	Levonorgestrel	13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one|Lvonorgestrel|17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol|Postinor|Levonorgestrelum|13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one|13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one|(-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one|18-Methyl-17-alpha-ethynyl-19-nortestosterone|Levonova|(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one|NorLevo|Jadelle|17alpha-Ethynyl-18-homo-19-nortestosterone|17-alpha-Ethynyl-13-ethyl-19-nortestosterone|d(-)-Norgestrel|17-Ethynyl-18-methyl-19-nortestosterone|Microval|Levonorgestrel|Mirena|17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one|Levonelle|18-Methylnorethisterone|Microlut|17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one|Plan b|Microluton	option 2|levonest|sronyx|lillo	DRUGBANK	DB00367	C21H28O2	small molecule	G03AB03|G03FA11|G03AA07|G03AD01|G03AC03|G03FB09	797-63-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYNJERNGUHSAO-XUDSTZEESA-N
6457	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Ghebeh H (2007)	17415709	175788	388	Progesterone	Akrolutin|Lutogynon|(S)-Pregn-4-en-3,20-dione|Luteohormone|17alpha-Progesterone|Progesteron|delta(4)-Pregnene-3,20-dione|Crinone|(S)-Progesterone|Progesterona|Pregn-4-ene-3,20-dione|Progesterone|17-progesterone|Progestrone|Agolutin|(S)-4-Pregnene-3,20-dione|Corpus Luteum Hormone|Gelbkoerperhormon|Progesteronum|4-Pregnene-3,20-dione	gesterol in oil-liq im 50mg/ml	DRUGBANK	DB00396	C21H30O2	small molecule	G03DA04|G03FA04	57-83-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RJKFOVLPORLFTN-LEKSSAKUSA-N
6458	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lessey BA (2006)	17118173	175789	388	Progesterone	Akrolutin|Lutogynon|(S)-Pregn-4-en-3,20-dione|Luteohormone|17alpha-Progesterone|Progesteron|delta(4)-Pregnene-3,20-dione|Crinone|(S)-Progesterone|Progesterona|Pregn-4-ene-3,20-dione|Progesterone|17-progesterone|Progestrone|Agolutin|(S)-4-Pregnene-3,20-dione|Corpus Luteum Hormone|Gelbkoerperhormon|Progesteronum|4-Pregnene-3,20-dione	gesterol in oil-liq im 50mg/ml	DRUGBANK	DB00396	C21H30O2	small molecule	G03DA04|G03FA04	57-83-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RJKFOVLPORLFTN-LEKSSAKUSA-N
6459	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Yuri T (2007)	17203775	175786	388	Progesterone	Akrolutin|Lutogynon|(S)-Pregn-4-en-3,20-dione|Luteohormone|17alpha-Progesterone|Progesteron|delta(4)-Pregnene-3,20-dione|Crinone|(S)-Progesterone|Progesterona|Pregn-4-ene-3,20-dione|Progesterone|17-progesterone|Progestrone|Agolutin|(S)-4-Pregnene-3,20-dione|Corpus Luteum Hormone|Gelbkoerperhormon|Progesteronum|4-Pregnene-3,20-dione	gesterol in oil-liq im 50mg/ml	DRUGBANK	DB00396	C21H30O2	small molecule	G03DA04|G03FA04	57-83-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RJKFOVLPORLFTN-LEKSSAKUSA-N
6460	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Montero Girard G (2007)	17341305	175787	388	Progesterone	Akrolutin|Lutogynon|(S)-Pregn-4-en-3,20-dione|Luteohormone|17alpha-Progesterone|Progesteron|delta(4)-Pregnene-3,20-dione|Crinone|(S)-Progesterone|Progesterona|Pregn-4-ene-3,20-dione|Progesterone|17-progesterone|Progestrone|Agolutin|(S)-4-Pregnene-3,20-dione|Corpus Luteum Hormone|Gelbkoerperhormon|Progesteronum|4-Pregnene-3,20-dione	gesterol in oil-liq im 50mg/ml	DRUGBANK	DB00396	C21H30O2	small molecule	G03DA04|G03FA04	57-83-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RJKFOVLPORLFTN-LEKSSAKUSA-N
6461	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kumar AS (2007)	17103262	175785	388	Progesterone	Akrolutin|Lutogynon|(S)-Pregn-4-en-3,20-dione|Luteohormone|17alpha-Progesterone|Progesteron|delta(4)-Pregnene-3,20-dione|Crinone|(S)-Progesterone|Progesterona|Pregn-4-ene-3,20-dione|Progesterone|17-progesterone|Progestrone|Agolutin|(S)-4-Pregnene-3,20-dione|Corpus Luteum Hormone|Gelbkoerperhormon|Progesteronum|4-Pregnene-3,20-dione	gesterol in oil-liq im 50mg/ml	DRUGBANK	DB00396	C21H30O2	small molecule	G03DA04|G03FA04	57-83-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RJKFOVLPORLFTN-LEKSSAKUSA-N
6488	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Cascone T (2007)	17272980	175818	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6489	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Huether A (2007)	17266941	175819	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6490	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Smalley KS (2009)	18794803	175816	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6491	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Lu X (2010)	20812347	175817	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6492	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Adnane L (2006)	16757355	175807	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6493	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Wilhelm SM (2008)	18852116	175815	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6494	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Gridelli C (2007)	17296815	175811	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
6495	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	inhibitor	target	Gollob JA (2006)	16890795	175820	390	Sorafenib	N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea|Sorafenibum|4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide	nexavar	DRUGBANK	DB00398	C21H16ClF3N4O3	small molecule	L01XE05	284461-73-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLDQJTXFUGDVEO-UHFFFAOYSA-N
7238	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	agonist	target	Pertwee RG (2009)	19226257	176293	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7239	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	agonist	target	Davis M (2007)	17139494	176294	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7240	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7241	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7242	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7243	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	agonist	target	Pryce G (2003)	12686391	176295	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7244	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	agonist	target	Tsai SJ (2000)	11204352	176296	462	Dronabinol	6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol|9-tetrahydrocannabinol|delta-9-tetrahydrocannabinol|delta(1)-Tetrahydrocannabinol|(-)-delta9-trans-Tetrahydrocannabinol|3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol|Dronabinol|delta-9-THC|Dronabinolum|Tetrahydrocannabinol|delta9-Tetrahydrocannabinol|1-trans-delta-9-Tetrahydrocannabinol|delta(9)-THC	dronabinol|marinol|sativex|mar	DRUGBANK	DB00470	C21H30O2	small molecule	A04AD10	1972-08-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CYQFCXCEBYINGO-IAGOWNOFSA-N
7376	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Moen MD (2008)	18778124	176379	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7377	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7378	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Matsumoto T (2006)	16951478	176385	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7379	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Khovidhunkit W (1999)	10068418	176383	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7380	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Figtree GA (1999)	10477535	176382	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7381	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Cummings SR (1999)	10376571	176381	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7382	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Scott JA (1999)	10507743	176380	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7383	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Bryant HU (1999)	10418979	176378	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7384	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Schafer JI (1999)	10485477	176384	473	Raloxifene	(2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone|Keoxifene|RAL|Raloxifene|LY 139481|Raloxifeno|Raloxifenum	pms-raloxifene|evista|act ralo	DRUGBANK	DB00481	C28H27NO4S	small molecule	G03XC01	84449-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GZUITABIAKMVPG-UHFFFAOYSA-N
7425	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	partial agonist	target	Kraft B (2004)	15221424	176431	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7426	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	partial agonist	target	Conti S (2002)	11786493	176430	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7427	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	partial agonist	target	Darmani NA (2001)	11698062	176428	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7428	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	partial agonist	target	Mendizabal VE (2007)	17450170	176429	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7429	107669	1269	RP11-4M23.1	CNR2	CB-2|CB2|CX5	9606	Homo sapiens	partial agonist	target	Davis M (2007)	17139494	176294	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7430	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Hirst RA (1996)	8981483	176433	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7431	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Pertwee RG (1999)	10575283	176432	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7432	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Pertwee RG (1996)	8864542	176434	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7433	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Chen X (2002)	11752352	171740	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7434	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Davis M (2007)	17139494	176294	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7435	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	partial agonist	target	Darmani NA (2001)	11698062	176428	478	Nabilone	Nabilon|Cesamet|Nabilone|Nabilona|Nabilonum	act nabilone|cesamet|pms-nabil	DRUGBANK	DB00486	C24H36O3	small molecule	A04AD11	51022-71-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GECBBEABIDMGGL-RTBURBONSA-N
7498	112874	7015	-	TERT	CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT	9606	Homo sapiens	inhibitor	target	Leeansyah E (2013)	23303810	176483	487	Zidovudine	AZT|ZDV|Azidothymidine|Zidovudin|Zidovudinum	trizivir|retrovir (azt)|apo-la	DRUGBANK	DB00495	C10H13N5O4	small molecule	J05AR01|J05AF01|J05AR05|J05AR04	30516-87-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBOMLICNUCNMMY-XLPZGREQSA-N
7636	111817	5879	MIG5	RAC1	Rac-1|TC-25|p21-Rac1	9606	Homo sapiens	inhibitor	target	Zhang W (2004)	14734632	176580	504	Dextromethorphan	Dex|DM|Dextromthorphane|Dextromethorfan|Dextromethorphan|DXM|Dextrometorfano|D-methorphan|(+)-dextromethorphan|delta-Methorphan|Dextromethorphanum	tylenol cold and flu nighttime	DRUGBANK	DB00514	C18H25NO	small molecule	N07XX59|R05DA09	125-71-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MKXZASYAUGDDCJ-NJAFHUGGSA-N
7762	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Bulgaru AM (2003)	12820772	176686	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7763	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Kim TE (2002)	12498017	176687	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7764	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Akita RW (2003)	12840797	176684	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7765	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Laird AD (2003)	12517254	176685	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7766	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Delbaldo C (2003)	12814826	176683	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7767	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	520	Erlotinib	OSI-774|[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine|Erlotinib	pms-erlotinib|tarceva|teva-erl	DRUGBANK	DB00530	C22H23N3O4	small molecule	L01XE03	183321-74-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AAKJLRGGTJKAMG-UHFFFAOYSA-N
7806	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	526	Guanidine	Gu|Iminourea|Aminomethanamidine|Imidourea|Guanidin|H2N-C(=NH)-NH2|GUANIDINE	guanidine hydrochloride	DRUGBANK	DB00536	CH5N3	small molecule	-	113-00-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRALSGWEFCBTJO-UHFFFAOYSA-N
7807	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	526	Guanidine	Gu|Iminourea|Aminomethanamidine|Imidourea|Guanidin|H2N-C(=NH)-NH2|GUANIDINE	guanidine hydrochloride	DRUGBANK	DB00536	CH5N3	small molecule	-	113-00-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRALSGWEFCBTJO-UHFFFAOYSA-N
7808	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	526	Guanidine	Gu|Iminourea|Aminomethanamidine|Imidourea|Guanidin|H2N-C(=NH)-NH2|GUANIDINE	guanidine hydrochloride	DRUGBANK	DB00536	CH5N3	small molecule	-	113-00-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRALSGWEFCBTJO-UHFFFAOYSA-N
7814	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Lewis-Wambi JS (2006)	16917142	176743	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7815	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Liu X (2003)	12870885	176742	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7816	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Locci P (2001)	11747628	176741	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7817	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Gennari L (2007)	17503894	176740	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7818	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Shelly W (2008)	18279543	176738	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7819	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Jones KL (2004)	15369444	176739	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7820	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Ariazi EA (2006)	16515478	176736	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7821	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Goldstein LJ (2006)	16595024	176737	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7822	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Smith MR (2006)	17062721	176734	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7823	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Taneja SS (2006)	16503765	176735	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
7824	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Chen X (2002)	11752352	171740	529	Toremifene	Toremifenum|Toremifeno	fareston	DRUGBANK	DB00539	C26H28ClNO	small molecule	L02BA02	89778-26-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XFCLJVABOIYOMF-QPLCGJKRSA-N
8115	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Martinez-Campa C (2006)	16555127	176947	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8116	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Duan L (2007)	17126817	176949	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8117	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Obey TB (2005)	16111654	176948	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8118	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Brantley-Finley C (2003)	12907245	176950	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8119	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Bene A (2004)	15498923	176951	560	Vinblastine	Vinblastinum|(2alpha,2'BETA,3beta,4alpha,5beta)-vincaleukoblastine|Vinblastina|VLB|Vinblastine|Vinblastin|Vincaleukoblastine	vinblastine sulphate injection	DRUGBANK	DB00570	C46H58N4O9	small molecule	L01CA01	865-21-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXLYSJRDGCGARV-XQKSVPLYSA-N
8509	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Jain JK (2007)	17094978	177204	593	Medroxyprogesterone acetate	6-Methyl-17-hydroxyprogesterone acetate|(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione|Medroxyprogesterone acetate|17alpha-Hydroxy-6alpha-methylprogesterone acetate|Medroxyprogesterone 17-acetate|Metigestrona|6alpha-Methyl-17alpha-hydroxyprogesterone acetate|MPA|6-Methyl-17-acetoxy progesterone|6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate|17-Acetoxy-6alpha-methylprogesterone|6-alpha-Methyl-17-alpha-acetoxyprogesterone|17-hydroxy-6-methylprogesterone acetate|6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate|17-Acetoxy-6-methylprogesterone|Methylacetoxyprogesterone|6alpha-Methyl-17-acetoxy progesterone|Medroxyacetate progesterone	provera 2.5mg tablets|medroxy-	DRUGBANK	DB00603	C24H34O4	small molecule	G03AA08|G03FA12|G03FB06|G03DA02|G03AC06|L02AB02	71-58-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PSGAAPLEWMOORI-PEINSRQWSA-N
8510	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Ghebeh H (2007)	17415709	175788	593	Medroxyprogesterone acetate	6-Methyl-17-hydroxyprogesterone acetate|(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione|Medroxyprogesterone acetate|17alpha-Hydroxy-6alpha-methylprogesterone acetate|Medroxyprogesterone 17-acetate|Metigestrona|6alpha-Methyl-17alpha-hydroxyprogesterone acetate|MPA|6-Methyl-17-acetoxy progesterone|6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate|17-Acetoxy-6alpha-methylprogesterone|6-alpha-Methyl-17-alpha-acetoxyprogesterone|17-hydroxy-6-methylprogesterone acetate|6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate|17-Acetoxy-6-methylprogesterone|Methylacetoxyprogesterone|6alpha-Methyl-17-acetoxy progesterone|Medroxyacetate progesterone	provera 2.5mg tablets|medroxy-	DRUGBANK	DB00603	C24H34O4	small molecule	G03AA08|G03FA12|G03FB06|G03DA02|G03AC06|L02AB02	71-58-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PSGAAPLEWMOORI-PEINSRQWSA-N
8511	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lessey BA (2006)	17118173	175789	593	Medroxyprogesterone acetate	6-Methyl-17-hydroxyprogesterone acetate|(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione|Medroxyprogesterone acetate|17alpha-Hydroxy-6alpha-methylprogesterone acetate|Medroxyprogesterone 17-acetate|Metigestrona|6alpha-Methyl-17alpha-hydroxyprogesterone acetate|MPA|6-Methyl-17-acetoxy progesterone|6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate|17-Acetoxy-6alpha-methylprogesterone|6-alpha-Methyl-17-alpha-acetoxyprogesterone|17-hydroxy-6-methylprogesterone acetate|6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate|17-Acetoxy-6-methylprogesterone|Methylacetoxyprogesterone|6alpha-Methyl-17-acetoxy progesterone|Medroxyacetate progesterone	provera 2.5mg tablets|medroxy-	DRUGBANK	DB00603	C24H34O4	small molecule	G03AA08|G03FA12|G03FB06|G03DA02|G03AC06|L02AB02	71-58-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PSGAAPLEWMOORI-PEINSRQWSA-N
8512	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Yuri T (2007)	17203775	175786	593	Medroxyprogesterone acetate	6-Methyl-17-hydroxyprogesterone acetate|(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione|Medroxyprogesterone acetate|17alpha-Hydroxy-6alpha-methylprogesterone acetate|Medroxyprogesterone 17-acetate|Metigestrona|6alpha-Methyl-17alpha-hydroxyprogesterone acetate|MPA|6-Methyl-17-acetoxy progesterone|6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate|17-Acetoxy-6alpha-methylprogesterone|6-alpha-Methyl-17-alpha-acetoxyprogesterone|17-hydroxy-6-methylprogesterone acetate|6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate|17-Acetoxy-6-methylprogesterone|Methylacetoxyprogesterone|6alpha-Methyl-17-acetoxy progesterone|Medroxyacetate progesterone	provera 2.5mg tablets|medroxy-	DRUGBANK	DB00603	C24H34O4	small molecule	G03AA08|G03FA12|G03FB06|G03DA02|G03AC06|L02AB02	71-58-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PSGAAPLEWMOORI-PEINSRQWSA-N
8513	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kumar AS (2007)	17103262	175785	593	Medroxyprogesterone acetate	6-Methyl-17-hydroxyprogesterone acetate|(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione|Medroxyprogesterone acetate|17alpha-Hydroxy-6alpha-methylprogesterone acetate|Medroxyprogesterone 17-acetate|Metigestrona|6alpha-Methyl-17alpha-hydroxyprogesterone acetate|MPA|6-Methyl-17-acetoxy progesterone|6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate|17-Acetoxy-6alpha-methylprogesterone|6-alpha-Methyl-17-alpha-acetoxyprogesterone|17-hydroxy-6-methylprogesterone acetate|6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate|17-Acetoxy-6-methylprogesterone|Methylacetoxyprogesterone|6alpha-Methyl-17-acetoxy progesterone|Medroxyacetate progesterone	provera 2.5mg tablets|medroxy-	DRUGBANK	DB00603	C24H34O4	small molecule	G03AA08|G03FA12|G03FB06|G03DA02|G03AC06|L02AB02	71-58-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PSGAAPLEWMOORI-PEINSRQWSA-N
8550	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2001)	11245463	177238	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8551	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2004)	15548677	177239	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8552	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2003)	12566304	177235	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8553	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Pangburn HA (2005)	16138927	177236	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8554	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Rice PL (2006)	16546990	177237	595	Sulindac	cis-5-Fluoro-2-methyl-1-((P-methylsulfinyl)benzylidene)indene-3-acetic acid|Sulindac|Clinoril|Sulindaco|(Z)-5-Fluoro-2-methyl-1-((P-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|Sulindacum	sulindac|clinoril tab 150mg|ap	DRUGBANK	DB00605	C20H17FO3S	small molecule	M01AB02	38194-50-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLKXDPUZXIRXEP-MFOYZWKCSA-N
8582	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	unknown	target	Huang LY (2005)	16148144	177269	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8583	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	unknown	target	Rutz M (2004)	15307186	177268	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8584	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	unknown	target	Lenert P (2005)	15762869	177267	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8585	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	unknown	target	Trevani AS (2003)	14579285	177266	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
8586	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	unknown	target	Merrell MA (2006)	16849519	177265	598	Chloroquine	Chloraquine|Chloroquine|Chloroquina|Chloroquinum|Chloroquinium|Chlorochine|Chlorochin|N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine|Cloroquina	aralen|chloroquine|teva-chloro	DRUGBANK	DB00608	C18H26ClN3	small molecule	P01BA01	54-05-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHTVZRBIWZFKQO-UHFFFAOYSA-N
9046	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	645	Estrone	Folliculin|Estrona|Estronum|Estrone|follicular hormone|3-Hydroxy-1,3,5(10)-estratrien-17-one|Oestrone	oestrilin creme vaginale 1mg|e	DRUGBANK	DB00655	C18H22O2	small molecule	G03CA07|G03CC04	53-16-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNXHEGUUPJUMQT-CBZIJGRNSA-N
9047	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	645	Estrone	Folliculin|Estrona|Estronum|Estrone|follicular hormone|3-Hydroxy-1,3,5(10)-estratrien-17-one|Oestrone	oestrilin creme vaginale 1mg|e	DRUGBANK	DB00655	C18H22O2	small molecule	G03CA07|G03CC04	53-16-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNXHEGUUPJUMQT-CBZIJGRNSA-N
9048	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Margeat E (2003)	12547192	177584	645	Estrone	Folliculin|Estrona|Estronum|Estrone|follicular hormone|3-Hydroxy-1,3,5(10)-estratrien-17-one|Oestrone	oestrilin creme vaginale 1mg|e	DRUGBANK	DB00655	C18H22O2	small molecule	G03CA07|G03CC04	53-16-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DNXHEGUUPJUMQT-CBZIJGRNSA-N
9383	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Fabian CJ (2002)	11906441	177735	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9384	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9385	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9386	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Cyrus K (2010)	20512796	177734	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9387	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Fabian CJ (2002)	11906441	177735	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9388	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Sasson S (1991)	2011412	177583	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9389	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9390	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Cyrus K (2010)	20512796	177734	665	Tamoxifen	1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Citofen|Valodex|Tamoxifene|Tamoxifeno|Nourytam|(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine|Crisafeno|Tamone|1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene|Retaxim|Tamoxifenum|Apo-tamox|Tamoxifne|Zemide|Istubol|Noltam|Diemon|Tamofen|trans-Tamoxifen|Tamoxasta|Oncomox|Tamoxifen|Gen-tamoxifen|(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine	pms-tamoxifen|tamone  -  (20 m	DRUGBANK	DB00675	C26H29NO	small molecule	L02BA01	10540-29-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKANXQFJJICGDU-QPLCGJKRSA-N
9827	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	MacFarlane MD (1975)	1109354	178033	711	Procaine	Procaina|4-aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl 4-aminobenzoate|2-Diethylaminoethyl p-aminobenzoate|Vitamin H3|Procainum|Novocaine|p-Aminobenzoic acid 2-diethylaminoethyl ester|-(diethylamino)ethyl p-aminobenzoate	novocain 20 mg/ml|novocain liq	DRUGBANK	DB00721	C13H20N2O2	small molecule	S01HA05|C05AD05|N01BA52|N01BA02	59-46-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MFDFERRIHVXMIY-UHFFFAOYSA-N
10013	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	731	Hydrocortisone	11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione|Hidrocortisona|(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione|11beta-hydrocortisone|Hydrocortisonum|Reichstein's substance M|Hydrocortisone|(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione|Cortisol|4-Pregnen-11beta,17alpha,21-triol-3,20-dione|11-hydrocortisone|Kendall's compound F|17-Hydroxycorticosterone	kaiser permanente hydrocortiso	DRUGBANK	DB00741	C21H30O5	small molecule	S01BB01|D07XA01|S01CA03|D07BA04|D07AA02|D07CA01|A07EA02|A01AC03|D07AB02|D07AC16|S03CA04|S02CA03|C05AA01|H02AB09|D07BB04|S01CB03|S02BA01|R01AD60|S01BA02	50-23-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JYGXADMDTFJGBT-VWUMJDOOSA-N
10014	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Sato-Matsumura KC (2000)	11142771	178123	731	Hydrocortisone	11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione|Hidrocortisona|(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione|11beta-hydrocortisone|Hydrocortisonum|Reichstein's substance M|Hydrocortisone|(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione|Cortisol|4-Pregnen-11beta,17alpha,21-triol-3,20-dione|11-hydrocortisone|Kendall's compound F|17-Hydroxycorticosterone	kaiser permanente hydrocortiso	DRUGBANK	DB00741	C21H30O5	small molecule	S01BB01|D07XA01|S01CA03|D07BA04|D07AA02|D07CA01|A07EA02|A01AC03|D07AB02|D07AC16|S03CA04|S02CA03|C05AA01|H02AB09|D07BB04|S01CB03|S02BA01|R01AD60|S01BA02	50-23-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JYGXADMDTFJGBT-VWUMJDOOSA-N
10015	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	731	Hydrocortisone	11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione|Hidrocortisona|(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione|11beta-hydrocortisone|Hydrocortisonum|Reichstein's substance M|Hydrocortisone|(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione|Cortisol|4-Pregnen-11beta,17alpha,21-triol-3,20-dione|11-hydrocortisone|Kendall's compound F|17-Hydroxycorticosterone	kaiser permanente hydrocortiso	DRUGBANK	DB00741	C21H30O5	small molecule	S01BB01|D07XA01|S01CA03|D07BA04|D07AA02|D07CA01|A07EA02|A01AC03|D07AB02|D07AC16|S03CA04|S02CA03|C05AA01|H02AB09|D07BB04|S01CB03|S02BA01|R01AD60|S01BA02	50-23-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JYGXADMDTFJGBT-VWUMJDOOSA-N
10016	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Serres M (1994)	8060156	178125	731	Hydrocortisone	11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione|Hidrocortisona|(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione|11beta-hydrocortisone|Hydrocortisonum|Reichstein's substance M|Hydrocortisone|(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione|Cortisol|4-Pregnen-11beta,17alpha,21-triol-3,20-dione|11-hydrocortisone|Kendall's compound F|17-Hydroxycorticosterone	kaiser permanente hydrocortiso	DRUGBANK	DB00741	C21H30O5	small molecule	S01BB01|D07XA01|S01CA03|D07BA04|D07AA02|D07CA01|A07EA02|A01AC03|D07AB02|D07AC16|S03CA04|S02CA03|C05AA01|H02AB09|D07BB04|S01CB03|S02BA01|R01AD60|S01BA02	50-23-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JYGXADMDTFJGBT-VWUMJDOOSA-N
10017	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	White MV (1991)	1712816	178124	731	Hydrocortisone	11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione|Hidrocortisona|(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione|11beta-hydrocortisone|Hydrocortisonum|Reichstein's substance M|Hydrocortisone|(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione|Cortisol|4-Pregnen-11beta,17alpha,21-triol-3,20-dione|11-hydrocortisone|Kendall's compound F|17-Hydroxycorticosterone	kaiser permanente hydrocortiso	DRUGBANK	DB00741	C21H30O5	small molecule	S01BB01|D07XA01|S01CA03|D07BA04|D07AA02|D07CA01|A07EA02|A01AC03|D07AB02|D07AC16|S03CA04|S02CA03|C05AA01|H02AB09|D07BB04|S01CB03|S02BA01|R01AD60|S01BA02	50-23-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JYGXADMDTFJGBT-VWUMJDOOSA-N
10092	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Shioda K (2010)	20655983	178189	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10093	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Wiest SA (1999)	10494892	178188	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10094	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Salsali M (2004)	15049511	178194	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10095	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Todd KG (1995)	8749840	178187	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10096	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Finberg JP (2002)	12504917	178196	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10097	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Gatch MB (2006)	16495723	178197	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10098	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Nolen WA (2003)	14574774	178190	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10099	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Volz HP (1998)	9829163	178186	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10100	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Lang W (2004)	15351283	178192	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10101	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Shioda K (2004)	15276688	178191	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10102	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Cohen C (1999)	10548268	178195	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10103	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Loescher W (1999)	10027835	178193	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10104	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	742	Tranylcypromine	Tranylcypromin|Tranilcipromina|Transamine|Tranylcypromine|Parnate|Tranylcyprominum	parnate|tranylcypromine sulfat	DRUGBANK	DB00752	C9H11N	small molecule	N06AF04	155-09-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AELCINSCMGFISI-YGPZHTELSA-N
10153	106695	190	-	NR0B1	AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NROB1|SRXY2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10154	106695	190	-	NR0B1	AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NROB1|SRXY2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10387	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10388	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Nolen WA (2003)	14574774	178190	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10389	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Volz HP (1998)	9829163	178186	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10390	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	McIntyre RS (2006)	16370964	178345	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10391	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Wooters TE (2007)	17912044	178344	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10392	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Pickar D (1982)	7092487	178347	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10393	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Chiche F (2009)	19201819	178346	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10394	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	MacKenzie EM (2008)	17768678	178353	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10395	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	antagonist	target	Chenu F (2009)	18700056	178343	770	Phenelzine	Phenelzinum|Phenelzin|Alazine|Phnelzine|Nardil|-Phenylethylhydrazine|Fenelzina|Monofen	nardil|phenelzine sulfate	DRUGBANK	DB00780	C8H12N2	small molecule	N06AF03	51-71-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMUCZJUITONUFY-UHFFFAOYSA-N
10417	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	773	Estradiol	Estradiol|(17beta)-Estra-1,3,5(10)-triene-3,17-diol|beta-Estradiol|Dihydrotheelin|Dihydrofolliculin|17beta-Oestradiol|17beta Oestradiol|Femestral|Estradiolum|Benzhormovarine|Lio-Oid|17beta-Estra-1,3,5(10)-triene-3,17-diol|Dihydroxyestrin|Estradiol-17beta|cis-Estradiol|Dihydrofollicular hormone	climara 100|sandoz estradiol d	DRUGBANK	DB00783	C18H24O2	small molecule	G03CA03|G03FA13|G03FA12|G03FA11|G03FA10|G03FA17|G03FA16|G03FA15|G03FA14|G03CA53|G03AB08|G03FB10|G03FB11|G03FB12|G03FA08|G03FA09|G03EA01|G03EA03|G03EA02|G03FA01|G03FA02|G03FA03|G03FA04|G03FA05|G03FA06|G03FA07|G03AA14|G03HB01|G02BB01|G03FB03|G03FB02|G03FB01|G03FB07|G03FB06|G03FB05|G03FB04|G03FB09|G03FB08	50-28-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOXZDWNPVJITMN-ZBRFXRBCSA-N
10418	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lehnes K (2007)	17138652	178365	773	Estradiol	Estradiol|(17beta)-Estra-1,3,5(10)-triene-3,17-diol|beta-Estradiol|Dihydrotheelin|Dihydrofolliculin|17beta-Oestradiol|17beta Oestradiol|Femestral|Estradiolum|Benzhormovarine|Lio-Oid|17beta-Estra-1,3,5(10)-triene-3,17-diol|Dihydroxyestrin|Estradiol-17beta|cis-Estradiol|Dihydrofollicular hormone	climara 100|sandoz estradiol d	DRUGBANK	DB00783	C18H24O2	small molecule	G03CA03|G03FA13|G03FA12|G03FA11|G03FA10|G03FA17|G03FA16|G03FA15|G03FA14|G03CA53|G03AB08|G03FB10|G03FB11|G03FB12|G03FA08|G03FA09|G03EA01|G03EA03|G03EA02|G03FA01|G03FA02|G03FA03|G03FA04|G03FA05|G03FA06|G03FA07|G03AA14|G03HB01|G02BB01|G03FB03|G03FB02|G03FB01|G03FB07|G03FB06|G03FB05|G03FB04|G03FB09|G03FB08	50-28-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOXZDWNPVJITMN-ZBRFXRBCSA-N
10419	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	773	Estradiol	Estradiol|(17beta)-Estra-1,3,5(10)-triene-3,17-diol|beta-Estradiol|Dihydrotheelin|Dihydrofolliculin|17beta-Oestradiol|17beta Oestradiol|Femestral|Estradiolum|Benzhormovarine|Lio-Oid|17beta-Estra-1,3,5(10)-triene-3,17-diol|Dihydroxyestrin|Estradiol-17beta|cis-Estradiol|Dihydrofollicular hormone	climara 100|sandoz estradiol d	DRUGBANK	DB00783	C18H24O2	small molecule	G03CA03|G03FA13|G03FA12|G03FA11|G03FA10|G03FA17|G03FA16|G03FA15|G03FA14|G03CA53|G03AB08|G03FB10|G03FB11|G03FB12|G03FA08|G03FA09|G03EA01|G03EA03|G03EA02|G03FA01|G03FA02|G03FA03|G03FA04|G03FA05|G03FA06|G03FA07|G03AA14|G03HB01|G02BB01|G03FB03|G03FB02|G03FB01|G03FB07|G03FB06|G03FB05|G03FB04|G03FB09|G03FB08	50-28-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOXZDWNPVJITMN-ZBRFXRBCSA-N
10420	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Brama M (2007)	17125913	178366	773	Estradiol	Estradiol|(17beta)-Estra-1,3,5(10)-triene-3,17-diol|beta-Estradiol|Dihydrotheelin|Dihydrofolliculin|17beta-Oestradiol|17beta Oestradiol|Femestral|Estradiolum|Benzhormovarine|Lio-Oid|17beta-Estra-1,3,5(10)-triene-3,17-diol|Dihydroxyestrin|Estradiol-17beta|cis-Estradiol|Dihydrofollicular hormone	climara 100|sandoz estradiol d	DRUGBANK	DB00783	C18H24O2	small molecule	G03CA03|G03FA13|G03FA12|G03FA11|G03FA10|G03FA17|G03FA16|G03FA15|G03FA14|G03CA53|G03AB08|G03FB10|G03FB11|G03FB12|G03FA08|G03FA09|G03EA01|G03EA03|G03EA02|G03FA01|G03FA02|G03FA03|G03FA04|G03FA05|G03FA06|G03FA07|G03AA14|G03HB01|G02BB01|G03FB03|G03FB02|G03FB01|G03FB07|G03FB06|G03FB05|G03FB04|G03FB09|G03FB08	50-28-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOXZDWNPVJITMN-ZBRFXRBCSA-N
10445	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Shinoda K (2003)	12527923	178389	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10446	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Bernardo MM (2002)	11790786	178388	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10447	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10448	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Bourd-Boittin K (2005)	15748894	178385	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10449	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Fanchon S (2004)	15056115	178387	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10450	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Treharne GD (1999)	10460642	178386	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10451	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Nenan S (2007)	17234180	178390	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10452	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Underwood CK (2003)	12763661	178391	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10453	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10466	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10467	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10470	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10471	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10472	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10483	110466	4323	-	MMP14	MMP-14|MMP-X1|MT-MMP|MT-MMP 1|MT1-MMP|MT1MMP|MTMMP1|WNCHRS	9606	Homo sapiens	inhibitor	target	Heath EI (2000)	10852638	178392	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10484	110466	4323	-	MMP14	MMP-14|MMP-X1|MT-MMP|MT-MMP 1|MT1-MMP|MT1MMP|MTMMP1|WNCHRS	9606	Homo sapiens	inhibitor	target	Belotti D (2000)	10669951	178393	776	Marimastat	BB-2516|Marimastat	-	DRUGBANK	DB00786	C15H29N3O5	small molecule	-	154039-60-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OCSMOTCMPXTDND-OUAUKWLOSA-N
10560	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10561	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10562	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Weber CK (2000)	11054378	174546	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10563	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Allgayer H (2003)	12950415	174544	785	Sulfasalazine	Sulfasalazinum|Azopyrin|Salicylazosulfapyridine|Salazosulfapyridinum|Sulfasalazine|5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid|Azulfidine|Sulfasalazin|Salazosulfapiridina|5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid|4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene|5-(P-(2-Pyridylsulfamyl)phenylazo)salicylic acid|Salazosulfapyridine|2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid|Sulfasalazina|2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid	ratio-sulfasalazine tab 500mg|	DRUGBANK	DB00795	C18H14N4O5S	small molecule	A07EC01	599-79-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCEXYHBECQHGNR-QZQOTICOSA-N
10688	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Kan JP (1986)	3954800	178464	795	Minaprine	4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine|Minaprinum|4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin|Minaprina|N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine	-	DRUGBANK	DB00805	C17H22N4O	small molecule	N06AX07	25905-77-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LDMWSLGGVTVJPG-UHFFFAOYSA-N
10712	110962	4907	RP11-321N4.1	NT5E	CALJA|CD73|E5NT|NT|NT5|NTE|eN|eNT	9606	Homo sapiens	inhibitor	target	Ustunsoy H (2006)	16426349	178471	796	Pentoxifylline	Pentoxil|Trental|Pentoxifilina|Pentoxifyllinum|Pentoxifylline|Oxpentifylline|Pentoxifyllin	trental tab 400mg|gapeam budib	DRUGBANK	DB00806	C13H18N4O3	small molecule	C04AD03	6493-05-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BYPFEZZEUUWMEJ-UHFFFAOYSA-N
10713	110962	4907	RP11-321N4.1	NT5E	CALJA|CD73|E5NT|NT|NT5|NTE|eN|eNT	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	796	Pentoxifylline	Pentoxil|Trental|Pentoxifilina|Pentoxifyllinum|Pentoxifylline|Oxpentifylline|Pentoxifyllin	trental tab 400mg|gapeam budib	DRUGBANK	DB00806	C13H18N4O3	small molecule	C04AD03	6493-05-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BYPFEZZEUUWMEJ-UHFFFAOYSA-N
10836	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	813	Ethynodiol diacetate	Etynodiolum|17-Ethynyl-4-estrene-3,17-diol diacetate|3,17-Diacetoxy-19-nor-17-pregn-4-en-20-yne|Etynodiol|Etynodiol acetate|tynodiol|Etinodiol|17-Ethynyl-19-norandrost-4-ene-3,17-beta-diol diacetate|19-Nor-17-pregn-4-en-20-yne-3,17-diol diacetate|3, 17-Diacetoxy-17-ethynyl-4-oestrene|17-Ethynylestr-4-ene-3,17-diol acetate|17-Ethynyl-3,17-dihydroxy-4-estrene diacetate|Ethynodiol	kelnor 1/35|demulen 30 (28 day	DRUGBANK	DB00823	C24H32O4	small molecule	G03AA01|G03DC06|G03FA06	297-76-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONKUMRGIYFNPJW-KIEAKMPYSA-N
10837	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kappus H (1973)	4123746	178556	813	Ethynodiol diacetate	Etynodiolum|17-Ethynyl-4-estrene-3,17-diol diacetate|3,17-Diacetoxy-19-nor-17-pregn-4-en-20-yne|Etynodiol|Etynodiol acetate|tynodiol|Etinodiol|17-Ethynyl-19-norandrost-4-ene-3,17-beta-diol diacetate|19-Nor-17-pregn-4-en-20-yne-3,17-diol diacetate|3, 17-Diacetoxy-17-ethynyl-4-oestrene|17-Ethynylestr-4-ene-3,17-diol acetate|17-Ethynyl-3,17-dihydroxy-4-estrene diacetate|Ethynodiol	kelnor 1/35|demulen 30 (28 day	DRUGBANK	DB00823	C24H32O4	small molecule	G03AA01|G03DC06|G03FA06	297-76-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONKUMRGIYFNPJW-KIEAKMPYSA-N
10838	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	813	Ethynodiol diacetate	Etynodiolum|17-Ethynyl-4-estrene-3,17-diol diacetate|3,17-Diacetoxy-19-nor-17-pregn-4-en-20-yne|Etynodiol|Etynodiol acetate|tynodiol|Etinodiol|17-Ethynyl-19-norandrost-4-ene-3,17-beta-diol diacetate|19-Nor-17-pregn-4-en-20-yne-3,17-diol diacetate|3, 17-Diacetoxy-17-ethynyl-4-oestrene|17-Ethynylestr-4-ene-3,17-diol acetate|17-Ethynyl-3,17-dihydroxy-4-estrene diacetate|Ethynodiol	kelnor 1/35|demulen 30 (28 day	DRUGBANK	DB00823	C24H32O4	small molecule	G03AA01|G03DC06|G03FA06	297-76-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONKUMRGIYFNPJW-KIEAKMPYSA-N
11170	106957	467	RP11-338C15.1	ATF3	-	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11173	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11174	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
11350	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Sehgal SN (2003)	12742462	178847	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11351	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11352	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Dowling RJ (2010)	20005306	178848	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11353	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Shuuin T (2009)	19620795	178849	867	Sirolimus	(-)-Rapamycin|Rapamycin	rapamune oral solution|sirolim	DRUGBANK	DB00877	C51H79NO13	small molecule	L04AA10|S01XA23	53123-88-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QFJCIRLUMZQUOT-KLHQEZAJSA-N
11371	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Homburg R (2005)	15878925	178873	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11372	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Overbeek A (2009)	19761360	178872	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11373	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kurosawa T (2010)	20379036	178871	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11374	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Brown J (2009)	19821295	178870	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11375	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11376	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11377	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Hughes E (2010)	20091498	178868	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11378	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Unknown Authors (2006)	17055820	178869	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11379	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Homburg R (2008)	18320435	178867	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11380	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Homburg R (2005)	15878925	178873	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11381	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Overbeek A (2009)	19761360	178872	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11382	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Kurosawa T (2010)	20379036	178871	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11383	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Brown J (2009)	19821295	178870	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11384	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Sasson S (1991)	2011412	177583	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11385	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11386	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Hughes E (2010)	20091498	178868	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11387	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Unknown Authors (2006)	17055820	178869	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11388	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Homburg R (2008)	18320435	178867	872	Clomifene	Clomifeno|Clomifene|Clomiphene|Clomifenum	clomid|serophene tab 50mg|clom	DRUGBANK	DB00882	C26H28ClNO	small molecule	G03GB02	911-45-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKIRPKYJQBWNGO-OCEACIFDSA-N
11433	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Grove RI (1987)	3622377	178918	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11434	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Juriansz RL (1988)	3334987	178919	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11435	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Bovee TF (2004)	15276617	178914	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11436	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Maru BS (2009)	18976723	178915	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11437	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chae K (1998)	9558716	178916	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11438	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kuiper GG (1997)	9048584	178917	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11439	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	880	Dienestrol	Cycladiene|alpha-dienestrol diacetate|Dinestrol|Dehydrostilbestrol|Dienestrolum|DV|Dienestrol	ortho dienestrol crm	DRUGBANK	DB00890	C18H18O2	small molecule	G03CB01|G03CC02	13029-44-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFDFQCUYFHCNBW-SCGPFSFSSA-N
11656	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Murata M (2010)	20502722	179028	899	Zonisamide	1,2-Benzisoxazole-3-methanesulfonamide|Zonisamida|Zonisamidum|Benzo[D]isoxazol-3-yl-methanesulfonamide|3-(Sulfamoylmethyl)-1,2-benzisoxazole	zonegran|zonisamide	DRUGBANK	DB00909	C8H8N2O3S	small molecule	N03AX15	68291-97-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBQNRHZMVUUOMG-UHFFFAOYSA-N
11657	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Okada M (1995)	8991786	179032	899	Zonisamide	1,2-Benzisoxazole-3-methanesulfonamide|Zonisamida|Zonisamidum|Benzo[D]isoxazol-3-yl-methanesulfonamide|3-(Sulfamoylmethyl)-1,2-benzisoxazole	zonegran|zonisamide	DRUGBANK	DB00909	C8H8N2O3S	small molecule	N03AX15	68291-97-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBQNRHZMVUUOMG-UHFFFAOYSA-N
12003	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Cataldo VD (2009)	19589026	179158	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12004	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Fenaux P (2005)	16341239	179149	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12005	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Kaminskas E (2005)	15793220	179153	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12006	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	O'Dwyer K (2008)	18627335	179152	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12007	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Ghoshal K (2007)	17612710	179151	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12008	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Hollenbach PW (2010)	20126405	179150	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12009	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Leone G (2003)	14585280	179157	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12010	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Silverman LR (2002)	12011120	179156	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12011	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Glover AB (1987)	2443243	179155	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12012	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Silverman LR (2001)	11700387	179154	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12013	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMUSYJAQQFHJEW-KVTDHHQDSA-N
12156	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	acetylation	target	Alfonso LF (2009)	21475861	179244	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12172	110859	4792	-	NFKBIA	IKBA|MAD-3|NFKBI	9606	Homo sapiens	unknown	target	Stevenson MA (1999)	10553090	179248	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12173	110858	4791	-	NFKB2	CVID10|H2TF1|LYT-10|LYT10|NF-kB2|p100|p52	9606	Homo sapiens	antagonist	target	Kopp E (1994)	8052854	179249	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12174	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Kopp E (1994)	8052854	179249	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12176	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	unknown	target	Yin MJ (1998)	9817203	179251	935	Acetylsalicylic acid	2-Acetoxybenzenecarboxylic acid|cido acetilsaliclico|Polopiryna|Easprin|Azetylsalizylsaeure|Salicylic acid acetate|2-Acetoxybenzoic acid|Acide actylsalicylique|O-acetylsalicylic acid|ASA|Acide 2-(acetyloxy)benzoique|Acetylsalicylsaeure|Acetylsalicylic acid|o-acetoxybenzoic acid|Azetylsalizylsure|2-(ACETYLOXY)benzoic acid|Acidum acetylsalicylicum|Acetylsalicylate|o-carboxyphenyl acetate|Aspirin	medique medi seltzer|asatab 80	DRUGBANK	DB00945	C9H8O4	small molecule	N02BA51|A01AD05|B01AC06|C10BX06|N02BA71|B01AC56|C10BX01|C10BX02|C10BX05|C10BX04|M01BA03|C10BX08|N02BA01	50-78-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSYNRYMUTXBXSQ-UHFFFAOYSA-N
12189	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Curran M (2001)	11398912	179274	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12190	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Elkak AE (2002)	11922402	179275	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12191	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Morris C (2002)	12542403	179272	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12192	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Dow KH (2002)	12080538	179273	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12193	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Bundred N (2002)	12113237	179270	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12194	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Kabos P (2010)	20151846	179271	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12195	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12196	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	McKeage K (2004)	15018596	179269	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12197	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Jones SE (2005)	15865850	179268	937	Fulvestrant	ICI 182,780	faslodex	DRUGBANK	DB00947	C32H47F5O3S	small molecule	L02BA03	129453-61-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWUXBMIQPBEWFH-LQKBAPIOSA-N
12281	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Pasqualini JR (2003)	14670645	179325	947	Norgestimate	(+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester)|Dexnorgestrel Acetime|Norgestimato|D-13beta-Ethyl-17alpha-ethynyl-17beta-acetoxygon-4-en-3-one oxime|Norgestimatum|(17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime	tri-cyclen tablets - 21-day|fe	DRUGBANK	DB00957	C23H31NO3	small molecule	G03FA13|G03AA11	35189-28-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KIQQMECNKUGGKA-NMYWJIRASA-N
12282	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Juchem M (1990)	2175153	175067	947	Norgestimate	(+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester)|Dexnorgestrel Acetime|Norgestimato|D-13beta-Ethyl-17alpha-ethynyl-17beta-acetoxygon-4-en-3-one oxime|Norgestimatum|(17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime	tri-cyclen tablets - 21-day|fe	DRUGBANK	DB00957	C23H31NO3	small molecule	G03FA13|G03AA11	35189-28-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KIQQMECNKUGGKA-NMYWJIRASA-N
12283	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Shields-Botella J (2003)	14672731	175549	947	Norgestimate	(+)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one oxime acetate (ester)|Dexnorgestrel Acetime|Norgestimato|D-13beta-Ethyl-17alpha-ethynyl-17beta-acetoxygon-4-en-3-one oxime|Norgestimatum|(17alpha)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime	tri-cyclen tablets - 21-day|fe	DRUGBANK	DB00957	C23H31NO3	small molecule	G03FA13|G03AA11	35189-28-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KIQQMECNKUGGKA-NMYWJIRASA-N
12430	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Brama M (2007)	17125913	178366	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12431	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Micevych PE (2007)	17095591	179458	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12432	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Notch EG (2009)	19237207	179459	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12433	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12434	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lehnes K (2007)	17138652	178365	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12435	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Bennink HJ (2009)	19434891	179462	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12436	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Mukai H (2006)	17142999	179461	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12437	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Garcia-Segura LM (2006)	17124377	179460	967	Ethinyl Estradiol	17-ethinylestradiol|17-ethinyl-3,17-estradiol|17 alpha-Ethinylestradiol|Ethinyloestradiol|Ethinyl-Oestranol|Ethinylestradiolum|Etinilestradiol|17 alpha-Ethynyloestradiol|Ethinylestriol|17alpha-Ethinyl estradiol|Ethynylestradiol|17-ethynylestradiol|17-ethinyl-3,17-oestradiol|17 alpha-Ethynylestradiol|Ethynyloestradiol|Ethinylestradiol|Ethynyl estradiol	sronyx|linessa 21|levonorgestr	DRUGBANK	DB00977	C20H24O2	small molecule	G03AA09|G03AA08|G03AB01|L02AA03|G03AB07|G03AB04|G03AB05|G03AA01|G03AA03|G03AA02|G03AA05|G03AA04|G03AA07|G03AA06|G03AB02|G03CA01|G03AB03|G03AA16|G03AA15|G03AA12|G03AA13|G03AA10|G03AA11|G03AB06	57-63-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BFPYWIDHMRZLRN-RHKZOZTBNA-N
12579	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Jeon KI (2003)	12754408	179568	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
12580	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Youn HS (2006)	17034761	179569	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
12797	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Steinmeyer J (1998)	9413935	179698	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12798	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Sadowski T (2001)	11246672	179699	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12799	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Amin AR (1996)	8943052	179700	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12800	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	modulator	target	Oringer RJ (2002)	12211491	179701	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12802	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Yao JS (2004)	15256478	179704	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12803	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Sasamura H (2002)	11875741	179702	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12804	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Rocchetti R (2005)	16224178	179703	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12805	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Baptiste DC (2004)	15304547	179708	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12806	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Lee SM (2003)	14588118	179706	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12807	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Arvin KL (2002)	12112047	179707	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12808	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Dommergues MA (2003)	14568022	179705	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12809	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Chen M (2000)	10888929	179696	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12810	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	negative modulator	target	Kim HS (2009)	18977395	179697	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12820	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Koistinaho M (2005)	15674236	179720	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12821	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Sutton TA (2005)	15353401	179721	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12822	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Brundula V (2002)	12023318	179717	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12823	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Lee CZ (2006)	16395286	179719	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12824	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Machado LS (2006)	16846501	179718	1007	Minocycline	Minocyclinum|Minocyclin|Minociclina|7-Dimethylamino-6-demethyl-6-deoxytetracycline|Minociclinum|(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide	solodyn|phl-minocycline|apo-mi	DRUGBANK	DB01017	C23H27N3O7	small molecule	J01AA08|A01AB23	10118-90-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYKFCLLONBREIL-KVUCHLLUSA-N
12945	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Zhu ZS (2004)	15133856	179770	1018	Irbesartan	2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one|Irbesartan|Avapro|BMS 186295	ipg-irbesartan|dom-irbesartan|	DRUGBANK	DB01029	C25H28N6O	small molecule	C09DA04|C09CA04|C09DB05	138402-11-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YOSHYTLCDANDAN-UHFFFAOYSA-N
12946	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	unknown	target	Cheng SM (2004)	15210574	179769	1018	Irbesartan	2-Butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one|Irbesartan|Avapro|BMS 186295	ipg-irbesartan|dom-irbesartan|	DRUGBANK	DB01029	C25H28N6O	small molecule	C09DA04|C09CA04|C09DB05	138402-11-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YOSHYTLCDANDAN-UHFFFAOYSA-N
13021	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13022	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Oskouian B (1999)	10102370	47998	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13023	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Heiligtag SJ (2002)	12181752	179812	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13024	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Lupu R (2006)	17168665	179813	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13025	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Flavin R (2010)	20373869	179810	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13026	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Ronnett GV (2005)	15878185	179811	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13027	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Li JN (2001)	11245456	179814	1023	Cerulenin	Cerulenin|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide|(2R,3S)-3-((4e,7e)-Nona-4,7-dienoyl)oxirane-2-carboxamide	-	DRUGBANK	DB01034	C12H17NO3	small molecule	-	17397-89-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVEZIHKRYBHEFX-NQQPLRFYSA-N
13034	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Lee BH (2005)	16230360	179823	1024	Procainamide	Procainamida|Procainamide|Biocoryl|p-Aminobenzoic diethylaminoethylamide|Procainamidum|p-Amino-N-(2-diethylaminoethyl)benzamide	apo-procainamide cap 375mg|pro	DRUGBANK	DB01035	C13H21N3O	small molecule	C01BA02	51-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	REQCZEXYDRLIBE-UHFFFAOYSA-N
13035	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Oelke K (2004)	15188362	179822	1024	Procainamide	Procainamida|Procainamide|Biocoryl|p-Aminobenzoic diethylaminoethylamide|Procainamidum|p-Amino-N-(2-diethylaminoethyl)benzamide	apo-procainamide cap 375mg|pro	DRUGBANK	DB01035	C13H21N3O	small molecule	C01BA02	51-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	REQCZEXYDRLIBE-UHFFFAOYSA-N
13036	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Januchowski R (2005)	15795105	179821	1024	Procainamide	Procainamida|Procainamide|Biocoryl|p-Aminobenzoic diethylaminoethylamide|Procainamidum|p-Amino-N-(2-diethylaminoethyl)benzamide	apo-procainamide cap 375mg|pro	DRUGBANK	DB01035	C13H21N3O	small molecule	C01BA02	51-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	REQCZEXYDRLIBE-UHFFFAOYSA-N
13037	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Scheinbart LS (1991)	2066944	179820	1024	Procainamide	Procainamida|Procainamide|Biocoryl|p-Aminobenzoic diethylaminoethylamide|Procainamidum|p-Amino-N-(2-diethylaminoethyl)benzamide	apo-procainamide cap 375mg|pro	DRUGBANK	DB01035	C13H21N3O	small molecule	C01BA02	51-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	REQCZEXYDRLIBE-UHFFFAOYSA-N
13062	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Patkar AA (2006)	16641841	179836	1026	Selegiline	L-Deprenalin|Selegilinum|()-selegiline|Selegilina	dom-selegiline|mylan-selegilin	DRUGBANK	DB01037	C13H17N	small molecule	N04BD01	14611-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZLKOACVSPNER-UHFFFAOYSA-N
13063	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Azzaro AJ (2007)	17715422	179828	1026	Selegiline	L-Deprenalin|Selegilinum|()-selegiline|Selegilina	dom-selegiline|mylan-selegilin	DRUGBANK	DB01037	C13H17N	small molecule	N04BD01	14611-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZLKOACVSPNER-UHFFFAOYSA-N
13064	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Baker GB (2007)	17823646	179831	1026	Selegiline	L-Deprenalin|Selegilinum|()-selegiline|Selegilina	dom-selegiline|mylan-selegilin	DRUGBANK	DB01037	C13H17N	small molecule	N04BD01	14611-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZLKOACVSPNER-UHFFFAOYSA-N
13065	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Lee KC (2007)	19300583	179829	1026	Selegiline	L-Deprenalin|Selegilinum|()-selegiline|Selegilina	dom-selegiline|mylan-selegilin	DRUGBANK	DB01037	C13H17N	small molecule	N04BD01	14611-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZLKOACVSPNER-UHFFFAOYSA-N
13085	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13086	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Yasui K (2005)	15723633	179849	1030	Thalidomide	alpha-N-Phthalylglutaramide|-phthalimidoglutarimide|2,6-dioxo-3-phthalimidopiperidine|3-Phthalimidoglutarimide|(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide|(+-)-Thalidomide|N-Phthalylglutamic acid imide|alpha-(N-Phthalimido)glutarimide|N-Phthalyl-glutaminsaeure-imid|-N-phthalylglutaramide|N-Phthaloylglutamimide|Thalidomidum|-(N-phthalimido)glutarimide|()-N-(2,6-dioxo-3-piperidyl)phthalimide|1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline|Talidomida|N-(2,6-dioxo-3-piperidyl)phthalimide|()-thalidomide	thalomid	DRUGBANK	DB01041	C13H10N2O4	small molecule	L04AX02	50-35-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UEJJHQNACJXSKW-UHFFFAOYSA-N
13283	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	modulator	target	Palayoor ST (2012)	22668799	179903	1039	Ibuprofen	Mynosedin|Para-Isobutylhydratropic Acid|Advil|Nuprin|(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid|Apsifen|P-Isobutylhydratropic Acid|Butylenin|alpha-(4-Isobutylphenyl)propionic acid|4-Isobutylhydratropic acid|Rufen|Tabalon|Femadon|(RS)-ibuprofen|Buburone|Haltran|Anflagen|Dolo-dolgit|Epobron|Amibufen|Urem|Trendar|(+-)-Ibuprofen|(+-)-2-(P-Isobutylphenyl)propionic acid|(+-)-P-Isobutylhydratropic acid|Motrin|Ibuprophen|Nobfen|Brufort|Brufen|Dolgit|Ibutid|alpha-(P-Isobutylphenyl)propionic acid|Ebufac|Nurofen|Anco|Ibuprofen|Lebrufen|Suspren|Dolgirid|Bluton|Dolgin|Pediaprofen|2-(4-Isobutylphenyl)propanoic acid|Seclodin|Roidenin|Ibuprocin|Nobgen|Inoven|Ibu-attritin|Lamidon|(4-Isobutylphenyl)-alpha-methylacetic acid|Adran|Medipren|Ibumetin|Liptan|Inabrin	advil cold and sinus nighttime	DRUGBANK	DB01050	C13H18O2	small molecule	M01AE01|M02AA13|G02CC01|R02AX02|C01EB16|M01AE51	15687-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HEFNNWSXXWATRW-UHFFFAOYSA-N
13356	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Dubey RK (2004)	15292328	179944	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13357	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Oudit GY (2003)	12963636	179940	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13358	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Vaniotis G (2011)	20732414	179941	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13359	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Azzi M (2003)	13679574	179942	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13360	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Yeh CK (2005)	15689414	179943	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13361	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Adissu HA (2004)	15138589	179939	1052	Isoprenaline	(+-)-Isoprenaline|Isoproterenol|Isoprenalina|N-isopropyl--dihydroxyphenyl--hydroxyethylamine|(+-)-Isoproterenol|N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine|Isoprenaline|Isopropyl noradrenaline|alpha-(Isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol|()-isoprenaline|Isoprenalinum|N-Isopropylnorepinephrine|()-isoproterenol|3,4-Dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol|-(isopropylaminomethyl)protocatechuyl alcohol|1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol|N-Isopropylnoradrenaline	isuprel mistometer aem 0.25%|i	DRUGBANK	DB01064	C11H17NO3	small molecule	R03AK02|R03AB02|C01CA02|R03CB01|R03CB51	7683-59-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JWZZKOKVBUJMES-UHFFFAOYSA-N
13387	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	del Rio B (2004)	15229223	179956	1053	Melatonin	5-methoxy-N-acetyltryptamine|Melatonin|N-Acetyl-5-methoxytryptamine|Melatonine|N-[2-(5-methoxyindol-3-yl)ethyl]acetamide	-	DRUGBANK	DB01065	C13H16N2O2	small molecule	N05CH01	73-31-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DRLFMBDRBRZALE-UHFFFAOYSA-N
13388	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Yoo YM (2009)	19796047	179955	1053	Melatonin	5-methoxy-N-acetyltryptamine|Melatonin|N-Acetyl-5-methoxytryptamine|Melatonine|N-[2-(5-methoxyindol-3-yl)ethyl]acetamide	-	DRUGBANK	DB01065	C13H16N2O2	small molecule	N05CH01	73-31-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DRLFMBDRBRZALE-UHFFFAOYSA-N
13593	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Purohit VC (2006)	16749788	180052	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13594	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Kremer L (2005)	16091048	180053	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13595	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Kridel SJ (2004)	15026345	180050	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13596	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Knowles LM (2004)	15138278	180051	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13597	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Menendez JA (2005)	15870086	180054	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13598	108488	2194	-	FASN	FAS|OA-519|SDR27X1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1071	Orlistat	(-)-Tetrahydrolipstatin|Xenical|Orlipastat|Orlipastatum|Tetrahydrolipstatin	xenical|xenical 120mg capsule|	DRUGBANK	DB01083	C29H53NO5	small molecule	A08AB01	96829-58-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHLBNYSZXLDEJQ-FWEHEUNISA-N
13716	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Wyszynski MW (1993)	8441637	180122	1087	Flucytosine	5-Fluorocystosine|5-Fluorocytosin|Flucytosine|5-Fluorocytosine|5-Flurocytosine|Fluorcytosine|5-FC|Fluocytosine|Flucytosin|Ancobon (tn)	ancobon|flucytosine	DRUGBANK	DB01099	C4H4FN3O	small molecule	D01AE21|J02AX01	2022-85-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRECTZIEBJDKEO-UHFFFAOYSA-N
13717	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1087	Flucytosine	5-Fluorocystosine|5-Fluorocytosin|Flucytosine|5-Fluorocytosine|5-Flurocytosine|Fluorcytosine|5-FC|Fluocytosine|Flucytosin|Ancobon (tn)	ancobon|flucytosine	DRUGBANK	DB01099	C4H4FN3O	small molecule	D01AE21|J02AX01	2022-85-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRECTZIEBJDKEO-UHFFFAOYSA-N
13718	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1087	Flucytosine	5-Fluorocystosine|5-Fluorocytosin|Flucytosine|5-Fluorocytosine|5-Flurocytosine|Fluorcytosine|5-FC|Fluocytosine|Flucytosin|Ancobon (tn)	ancobon|flucytosine	DRUGBANK	DB01099	C4H4FN3O	small molecule	D01AE21|J02AX01	2022-85-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRECTZIEBJDKEO-UHFFFAOYSA-N
13719	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	unknown	target	Shieh FK (2007)	17897676	180123	1087	Flucytosine	5-Fluorocystosine|5-Fluorocytosin|Flucytosine|5-Fluorocytosine|5-Flurocytosine|Fluorcytosine|5-FC|Fluocytosine|Flucytosin|Ancobon (tn)	ancobon|flucytosine	DRUGBANK	DB01099	C4H4FN3O	small molecule	D01AE21|J02AX01	2022-85-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRECTZIEBJDKEO-UHFFFAOYSA-N
13825	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	allosteric modulator	target	Barker S (2006)	16806905	180192	1096	Trilostane	Trilostano|Trilostanum	-	DRUGBANK	DB01108	C20H27NO3	small molecule	H02CA01	13647-35-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KVJXBPDAXMEYOA-CXANFOAXSA-N
13826	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	allosteric modulator	target	Puddefoot JR (2002)	12209583	180191	1096	Trilostane	Trilostano|Trilostanum	-	DRUGBANK	DB01108	C20H27NO3	small molecule	H02CA01	13647-35-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KVJXBPDAXMEYOA-CXANFOAXSA-N
13827	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	allosteric modulator	target	Puddefoot JR (2006)	17109615	180190	1096	Trilostane	Trilostano|Trilostanum	-	DRUGBANK	DB01108	C20H27NO3	small molecule	H02CA01	13647-35-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KVJXBPDAXMEYOA-CXANFOAXSA-N
13961	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Mamputu JC (2004)	14746574	180261	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13962	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Kimura T (2007)	17602961	180260	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13963	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Mamputu JC (2002)	12126787	180263	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
13964	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Li L (2006)	17046555	180262	1108	Gliclazide	1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea|Gliclazida|1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea|Gliclazidum|N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea	sandoz gliclazide|glic|nu-glic	DRUGBANK	DB01120	C15H21N3O3S	small molecule	A10BB09	21187-98-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOVGTQGAOIONJV-BETUJISGNA-N
14066	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	de Boer RA (2001)	11378004	180311	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14067	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Shyu KG (2005)	15732037	180310	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14068	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Shyu KG (2005)	15942707	180313	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14069	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Saijonmaa O (2004)	15071347	180312	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14084	109338	3091	-	HIF1A	HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78	9606	Homo sapiens	modulator	target	Shyu KG (2005)	15732037	180310	1124	Carvedilol	(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol|Carvedilolum|SKF 105517|Carvedilol	novo-carvedilol tablets|mylan-	DRUGBANK	DB01136	C24H26N2O4	small molecule	C07AG02	72956-09-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGHNVEJMJSYVRP-UHFFFAOYSA-N
14398	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Kietzmann T (2003)	12637567	180441	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14399	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Li J (2003)	12547826	180437	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14400	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Dong Z (2002)	12426127	180438	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14401	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Drobna Z (2003)	12475910	180439	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14402	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	inducer	target	Muscarella DE (2002)	12075113	180440	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14403	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	Dong Z (2002)	12426127	180438	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14404	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inducer	target	He Z (2003)	12529330	180442	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14405	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inducer	target	Tsou TC (2005)	16239170	180445	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14406	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inducer	target	Fauconneau B (2002)	12472888	180444	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14407	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inducer	target	Ivanov VN (2005)	15580309	180446	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14408	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inducer	target	Wang ZX (2005)	15916724	180443	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14409	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inducer	target	He Z (2003)	12529330	180442	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14411	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Fauconneau B (2002)	12472888	180444	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14412	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Tanaka-Kagawa T (2003)	14674888	180447	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14413	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Jung DK (2003)	14516795	180449	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14414	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Mousa SA (2007)	17158527	180448	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14415	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inducer	target	Felix K (2005)	15849723	180450	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14416	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Chen X (2002)	11752352	171740	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14417	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2007)	17450217	180452	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14418	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2005)	16230390	180453	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14419	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inducer	target	Ouyang W (2006)	16387740	180451	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14420	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Hwang BJ (2006)	17005224	180456	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14421	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2007)	17370311	180454	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14422	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Hyun Park W (2003)	12480548	180455	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14423	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2005)	16230390	180453	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14424	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2006)	16387740	180451	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14428	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1159	Moclobemide	p-Chloro-N-(2-morpholinoethyl)benzamide|Moclobemida|4-Chloro-N-(2-(4-morpholinyl)ethyl)benzamide|Moclobemidum|Moclaime|Moclamine|4-Chlor-N-(2-morpholinoethyl)benzamid|4-Chloro-N-(2-morpholin-4-yl-ethyl)-benzamide|Aurorix|Moclamide|Moclobemide|Moclobemid	manerix|nu-moclobemide|manerix	DRUGBANK	DB01171	C13H17ClN2O2	small molecule	N06AG02	71320-77-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YHXISWVBGDMDLQ-UHFFFAOYSA-N
14429	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Berlin I (1990)	1705137	180461	1159	Moclobemide	p-Chloro-N-(2-morpholinoethyl)benzamide|Moclobemida|4-Chloro-N-(2-(4-morpholinyl)ethyl)benzamide|Moclobemidum|Moclaime|Moclamine|4-Chlor-N-(2-morpholinoethyl)benzamid|4-Chloro-N-(2-morpholin-4-yl-ethyl)-benzamide|Aurorix|Moclamide|Moclobemide|Moclobemid	manerix|nu-moclobemide|manerix	DRUGBANK	DB01171	C13H17ClN2O2	small molecule	N06AG02	71320-77-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YHXISWVBGDMDLQ-UHFFFAOYSA-N
14430	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Fulton B (1996)	8875133	180460	1159	Moclobemide	p-Chloro-N-(2-morpholinoethyl)benzamide|Moclobemida|4-Chloro-N-(2-(4-morpholinyl)ethyl)benzamide|Moclobemidum|Moclaime|Moclamine|4-Chlor-N-(2-morpholinoethyl)benzamid|4-Chloro-N-(2-morpholin-4-yl-ethyl)-benzamide|Aurorix|Moclamide|Moclobemide|Moclobemid	manerix|nu-moclobemide|manerix	DRUGBANK	DB01171	C13H17ClN2O2	small molecule	N06AG02	71320-77-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YHXISWVBGDMDLQ-UHFFFAOYSA-N
14530	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Farooqui M (2006)	16546975	180500	1171	Naloxone	Naloxona|N-Allylnoroxymorphone|Nalossone|Naloxone|L-Naloxone|1-N-Allyl-14-hydroxynordihydromorphinone|EN 1530 Base|17-Allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one|Naloxonum	naloxone hydrochloride|naloxon	DRUGBANK	DB01183	C19H21NO4	small molecule	V03AB15	465-65-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZHSEJADLWPNLE-GRGSLBFTSA-N
14552	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	inhibitor	target	Lewis SS (2012)	22520687	180516	1171	Naloxone	Naloxona|N-Allylnoroxymorphone|Nalossone|Naloxone|L-Naloxone|1-N-Allyl-14-hydroxynordihydromorphinone|EN 1530 Base|17-Allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one|Naloxonum	naloxone hydrochloride|naloxon	DRUGBANK	DB01183	C19H21NO4	small molecule	V03AB15	465-65-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZHSEJADLWPNLE-GRGSLBFTSA-N
14566	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Sledge GW (2000)	10637238	180526	1173	Fluoxymesterone	9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one|Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-|17-Methyl-9-fluoro-11-hydroxytesterone|Fluoxymesteronum|Fluoximesterona|11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one|17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone|9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone	androxy|halotestin	DRUGBANK	DB01185	C20H29FO3	small molecule	G03BA01	76-43-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YLRFCQOZQXIBAB-RBZZARIASA-N
14567	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Perloff M (1996)	8622076	180527	1173	Fluoxymesterone	9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one|Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-|17-Methyl-9-fluoro-11-hydroxytesterone|Fluoxymesteronum|Fluoximesterona|11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one|17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone|9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone	androxy|halotestin	DRUGBANK	DB01185	C20H29FO3	small molecule	G03BA01	76-43-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YLRFCQOZQXIBAB-RBZZARIASA-N
14568	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Swain SM (1988)	3058238	180524	1173	Fluoxymesterone	9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one|Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-|17-Methyl-9-fluoro-11-hydroxytesterone|Fluoxymesteronum|Fluoximesterona|11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one|17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone|9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone	androxy|halotestin	DRUGBANK	DB01185	C20H29FO3	small molecule	G03BA01	76-43-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YLRFCQOZQXIBAB-RBZZARIASA-N
14569	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Pearson OH (1982)	7044524	180525	1173	Fluoxymesterone	9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one|Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-|17-Methyl-9-fluoro-11-hydroxytesterone|Fluoxymesteronum|Fluoximesterona|11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one|17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone|9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone	androxy|halotestin	DRUGBANK	DB01185	C20H29FO3	small molecule	G03BA01	76-43-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YLRFCQOZQXIBAB-RBZZARIASA-N
14570	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Ingle JN (2006)	16538529	180528	1173	Fluoxymesterone	9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one|Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-|17-Methyl-9-fluoro-11-hydroxytesterone|Fluoxymesteronum|Fluoximesterona|11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one|17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone|9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone	androxy|halotestin	DRUGBANK	DB01185	C20H29FO3	small molecule	G03BA01	76-43-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YLRFCQOZQXIBAB-RBZZARIASA-N
14710	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Tew KD (1983)	6364362	180571	1184	Estramustine	Estramustinum|Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)|17beta-Estradiol 3-(bis(2-chloroethyl)carbamate)|17-Estradiol 3-(bis(2-chloroethyl)carbamate)|Estramustina|Estramustine	emcyt cap 140mg|emcyt	DRUGBANK	DB01196	C23H31Cl2NO3	small molecule	L01XX11	2998-57-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRPJXPJMRWBBIH-RBRWEJTLSA-N
14711	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	von Schoultz E (1994)	7703721	180570	1184	Estramustine	Estramustinum|Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)|17beta-Estradiol 3-(bis(2-chloroethyl)carbamate)|17-Estradiol 3-(bis(2-chloroethyl)carbamate)|Estramustina|Estramustine	emcyt cap 140mg|emcyt	DRUGBANK	DB01196	C23H31Cl2NO3	small molecule	L01XX11	2998-57-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRPJXPJMRWBBIH-RBRWEJTLSA-N
14712	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Yoshizumi N (1985)	3989343	180568	1184	Estramustine	Estramustinum|Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)|17beta-Estradiol 3-(bis(2-chloroethyl)carbamate)|17-Estradiol 3-(bis(2-chloroethyl)carbamate)|Estramustina|Estramustine	emcyt cap 140mg|emcyt	DRUGBANK	DB01196	C23H31Cl2NO3	small molecule	L01XX11	2998-57-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRPJXPJMRWBBIH-RBRWEJTLSA-N
14713	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Fernoe M (1987)	3314674	180569	1184	Estramustine	Estramustinum|Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)|17beta-Estradiol 3-(bis(2-chloroethyl)carbamate)|17-Estradiol 3-(bis(2-chloroethyl)carbamate)|Estramustina|Estramustine	emcyt cap 140mg|emcyt	DRUGBANK	DB01196	C23H31Cl2NO3	small molecule	L01XX11	2998-57-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRPJXPJMRWBBIH-RBRWEJTLSA-N
14720	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Williams RN (2005)	15993560	180580	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14721	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Brower GL (2007)	17308006	180581	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14722	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Reinhardt D (2002)	12381651	180579	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14723	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Okada M (2008)	19057128	180578	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14724	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Prontera C (1999)	10328230	180577	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14725	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	inhibitor	target	Yamamoto D (2010)	20184869	180576	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14733	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Williams RN (2005)	15993560	180580	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14734	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Okada M (2008)	19057128	180578	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14735	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Yamamoto D (2008)	18501888	180584	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
14736	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	inhibitor	target	Reinhardt D (2002)	12381651	180579	1185	Captopril	(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid|Captopryl|Apopril|Garranil|Tensoprel|Cesplon|Capoten|D-3-Mercapto-2-methylpropanoyl-L-proline|Captoprilum|D-2-Methyl-3-mercaptopropanoyl-L-proline|Dilabar|Captoril|Hypertil|Captolane|Tensobon|Acepress|CP|Tenosbon|L-Captopril|Lopirin	capoten tab 100mg|med captopri	DRUGBANK	DB01197	C9H15NO3S	small molecule	C09AA01|C09BA01	62571-86-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAKRSMQSSFJEIM-RQJHMYQMSA-N
15113	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Matsuyoshi S (2006)	17119350	180733	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15114	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Thomadaki H (2006)	16895478	180737	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15115	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Yoshino T (2006)	17062688	180736	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15116	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Zhang X (2007)	17230521	180735	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15117	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Gan Y (2006)	16741658	180734	1217	Paclitaxel	5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine|(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester|Taxol|Taxol A|Paclitaxel	abraxane|paclitaxel injection,	DRUGBANK	DB01229	C47H51NO14	small molecule	L01CD01	33069-62-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RCINICONZNJXQF-MZXODVADSA-N
15163	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Morand EF (2006)	16883066	180762	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15164	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Davies E (2007)	17158208	180763	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15165	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	John CD (2006)	17076770	180764	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15166	106798	301	RP11-71A24.1	ANXA1	ANX1|LPC1	9606	Homo sapiens	agonist	target	Wang C (2007)	17644190	180765	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15167	106695	190	-	NR0B1	AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NROB1|SRXY2	9606	Homo sapiens	stimulator	target	Gummow BM (2006)	16857744	180766	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15168	106695	190	-	NR0B1	AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NROB1|SRXY2	9606	Homo sapiens	stimulator	target	Yu CC (2006)	17526944	180767	1222	Dexamethasone	Decadron|9-Fluoro-16-methylprednisolone|Dexamethasonum|9alpha-Fluoro-16alpha-methylprednisolone|16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol|16-Methyl-9-fluoro-1-dehydrocortisol|1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone|Dexamethasone|Dexametasona|1-Dehydro-16-methyl-9-fluorohydrocortisone	cresophene liq|maxidex ont 0.1	DRUGBANK	DB01234	C22H29FO5	small molecule	S01CA01|D10AA03|S02BA06|S01CB01|S03BA01|A01AC02|S02CA06|H02AB02|D07AB19|S03CA01|R01AD53|R01AD03|S01BA01|D07XB05|C05AA09|D07CB04	50-02-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UREBDLICKHMUKA-CXSFZGCWSA-N
15363	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Kettler R (1990)	2248058	180832	1235	Isocarboxazid	Isocarboxazide|Isocarboxazidum|Marplan|Isocarboxazida	marplan	DRUGBANK	DB01247	C12H13N3O2	small molecule	N06AF01	59-63-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKFPYPQQHFEXRZ-UHFFFAOYSA-N
15364	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Thase ME (1995)	7612154	180834	1235	Isocarboxazid	Isocarboxazide|Isocarboxazidum|Marplan|Isocarboxazida	marplan	DRUGBANK	DB01247	C12H13N3O2	small molecule	N06AF01	59-63-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKFPYPQQHFEXRZ-UHFFFAOYSA-N
15365	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1235	Isocarboxazid	Isocarboxazide|Isocarboxazidum|Marplan|Isocarboxazida	marplan	DRUGBANK	DB01247	C12H13N3O2	small molecule	N06AF01	59-63-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKFPYPQQHFEXRZ-UHFFFAOYSA-N
15366	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Inoue Y (2005)	15643508	180835	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15367	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Magi-Galluzzi C (2007)	17674353	180836	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15368	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Marshall J (2004)	15277270	180837	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15369	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Gligorov J (2004)	15161985	180838	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15370	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Petrylak DP (2005)	15685445	180839	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15371	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Miyoshi Y (2005)	15714982	180840	1236	Docetaxel	N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel|TXL|N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol|Docetaxel anhydrous	taxotere|docetaxel for injecti	DRUGBANK	DB01248	C43H53NO14	small molecule	L01CD02	114977-28-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
15380	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Ito R (2006)	17034586	180845	1238	Olsalazine	Dipentum	dipentum	DRUGBANK	DB01250	C14H10N2O6	small molecule	A07EC03	15722-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QQBDLJCYGRGAKP-FOCLMDBBSA-N
15381	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Egan LJ (1998)	9797390	180846	1238	Olsalazine	Dipentum	dipentum	DRUGBANK	DB01250	C14H10N2O6	small molecule	A07EC03	15722-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QQBDLJCYGRGAKP-FOCLMDBBSA-N
15403	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Schittenhelm MM (2006)	16397263	180858	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15404	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Quintas-Cardama A (2006)	17155893	180859	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15405	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Chen X (2002)	11752352	171740	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15406	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Kamath AV (2008)	17429625	180862	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15407	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Nam S (2005)	16230377	180861	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15408	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	multitarget	target	Serrels A (2006)	17148760	180860	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15422	112654	6777	-	STAT5B	STAT5	9606	Homo sapiens	inhibitor	target	Nam S (2007)	17431118	180869	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15423	112654	6777	-	STAT5B	STAT5	9606	Homo sapiens	inhibitor	target	Fiskus W (2006)	17020995	180868	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15446	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Zhou H (2004)	14751502	180891	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15447	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Burris HA (2004)	15163842	180890	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15448	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Xia W (2004)	14737100	180889	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15449	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Vazquez-Martin A (2011)	20658522	180888	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15450	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Grana TM (2003)	14633707	180885	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15451	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Wood ER (2004)	15374980	180884	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15452	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Johnston SR (2006)	16894399	180887	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15453	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Xia W (2002)	12214266	180886	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15454	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Langer CJ (2004)	14967461	180881	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15455	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15456	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Tevaarwerk AJ (2010)	20110044	180883	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15457	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Medina PJ (2008)	18803986	180882	1246	Lapatinib	GW 572016|N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine|Lapatinib tosilate hydrate|N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine|FMM|Tykerb	tykerb	DRUGBANK	DB01259	C29H26ClFN4O4S	small molecule	L01XE07	231277-92-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BCFGMOOMADDAQU-UHFFFAOYSA-N
15485	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Csankovszki G (2001)	11352938	131895	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15486	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15487	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Daskalakis M (2010)	20072836	180910	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15488	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Oki Y (2007)	17023173	180908	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15489	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Takebayashi S (2001)	11688997	91253	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15490	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Saba HI (2005)	16015501	180912	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15491	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Stresemann C (2008)	18425818	180905	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15492	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Jabbour E (2008)	18398832	180906	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15493	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Karpf AR (2001)	11259619	180907	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15494	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Saunthararajah Y (2003)	12907443	180911	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15495	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor	target	Ando T (2000)	11069027	180909	1249	Decitabine	Azadc|5-Azadeoxycytidine|Decitabine|5-aza-2'-deoxycytidine|4-amino-1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-S-triazin-2(1H)-one|Dezocitidine	decitabine|dacogen	DRUGBANK	DB01262	C8H12N4O4	small molecule	L01BC08	2353-33-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XAUDJQYHKZQPEU-KVQBGUIXSA-N
15594	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Heymach JV (2006)	16857825	180948	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15595	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Cohen RB (2003)	12620146	180949	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15596	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Chen X (2002)	11752352	171740	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15597	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Foon KA (2004)	14967460	180947	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15598	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Keating GM (2010)	20481659	180957	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15599	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Yang XD (2001)	11255078	180956	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15600	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Segaert S (2005)	16012181	180955	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15601	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Lynch DH (2002)	11894013	180954	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15602	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Saadeh CE (2007)	17355997	180953	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15603	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Wu M (2008)	18343240	180952	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15604	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Jean GW (2008)	18503402	180951	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15605	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	suppressor	target	Keating GM (2010)	20623992	180950	1256	Panitumumab	ABX-EGF	vectibix	DRUGBANK	DB01269	-	biologic	L01XC08	339177-26-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15606	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Ferrara N (2006)	17031284	180966	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15607	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gaudreault J (2007)	18046235	180967	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15608	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Kourlas H (2007)	18035187	180964	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15609	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Spitzer MS (2008)	19668384	180965	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15610	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Pieramici DJ (2006)	17049020	180962	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15611	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Nguyen QD (2006)	17046701	180963	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15612	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Michels S (2005)	15973626	180960	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15613	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Rosenfeld PJ (2006)	16935211	180961	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15614	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Gaudreault J (2005)	15671306	180959	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15615	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Bakri SJ (2007)	18054637	180958	1257	Ranibizumab	rhuFab V2	lucentis	DRUGBANK	DB01270	C2158H3282N562O681S12	biologic	S01LA04	347396-82-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15667	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Unknown Authors (2005)	15777106	181007	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15668	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Williams RM (2008)	18363546	181008	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15669	109707	3486	tcag7.703	IGFBP3	BP-53|IBP3	9606	Homo sapiens	unknown	target	Kemp SF (2009)	19627167	181009	1264	Mecasermin	IGF1|IGF-1|Mecasermin rinfabate recombinant|Mecasermin rinfabate|Mechano growth factor|Somatomedin-C|Insulin-like growth factor 1|Mecasermin recombinant	increlex	DRUGBANK	DB01277	C331H518N94O101S7	biologic	H01AC03|H01AC05	68562-41-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
15774	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Chen JT (2006)	16431966	181067	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15775	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Sarrazin S (2005)	16155294	181068	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15776	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Lortat-Jacob H (2006)	16709188	181069	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15777	109680	3458	-	IFNG	IFG|IFI	9606	Homo sapiens	unknown	target	Chen JT (2006)	17238806	181070	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15778	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Fenton JI (2002)	12405690	181073	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15779	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Dodge GR (2003)	12801482	181072	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15780	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Chu SC (2006)	16756968	181071	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15781	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Mendis E (2006)	16616490	181075	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15782	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	antagonist	target	Rajapakse N (2007)	17498959	181074	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
15788	110858	4791	-	NFKB2	CVID10|H2TF1|LYT-10|LYT10|NF-kB2|p100|p52	9606	Homo sapiens	antagonist	target	Largo R (2003)	12681956	181080	1278	Glucosamine	2-Amino-2-deoxy-D-glucose|Chitosamine|D-Glucosamine	remaxazon external patch	DRUGBANK	DB01296	C6H13NO5	small molecule	M01AX05	3416-24-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSWZFWKMSRAUBD-IVMDWMLBSA-N
16088	109187	2932	-	GSK3B	-	9606	Homo sapiens	inhibitor	target	Borsotto M (2007)	16733521	181143	1320	Lithium	Lithium, ion|Lithium cation|Lithium ion|Li(+)|Lithium, ion (li1+)	lithium carbonate|carbolith ca	DRUGBANK	DB01356	Li	small molecule	N05AN01	7439-93-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBBGRARXTFLTSG-UHFFFAOYSA-N
16089	109187	2932	-	GSK3B	-	9606	Homo sapiens	inhibitor	target	Adli M (2007)	17628506	181145	1320	Lithium	Lithium, ion|Lithium cation|Lithium ion|Li(+)|Lithium, ion (li1+)	lithium carbonate|carbolith ca	DRUGBANK	DB01356	Li	small molecule	N05AN01	7439-93-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBBGRARXTFLTSG-UHFFFAOYSA-N
16090	109187	2932	-	GSK3B	-	9606	Homo sapiens	inhibitor	target	O'Brien WT (2009)	19754466	181144	1320	Lithium	Lithium, ion|Lithium cation|Lithium ion|Li(+)|Lithium, ion (li1+)	lithium carbonate|carbolith ca	DRUGBANK	DB01356	Li	small molecule	N05AN01	7439-93-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBBGRARXTFLTSG-UHFFFAOYSA-N
16101	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Cleuren AC (2010)	20524981	181154	1321	Mestranol	-	ortho-novum 1/50 tablets (28 d	DRUGBANK	DB01357	C21H26O2	small molecule	-	72-33-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IMSSROKUHAOUJS-ZTUUXWJNNA-N
16102	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Dulos J (2010)	20497523	181155	1321	Mestranol	-	ortho-novum 1/50 tablets (28 d	DRUGBANK	DB01357	C21H26O2	small molecule	-	72-33-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IMSSROKUHAOUJS-ZTUUXWJNNA-N
16103	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	1321	Mestranol	-	ortho-novum 1/50 tablets (28 d	DRUGBANK	DB01357	C21H26O2	small molecule	-	72-33-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IMSSROKUHAOUJS-ZTUUXWJNNA-N
16139	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Ulus IH (2000)	10799660	174228	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16140	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Sulzer D (2005)	15955613	174152	1325	Ephedra	Chinese jointfir|Ma huang|Indian jointfir	stacker 2 nasal decongestant|e	DRUGBANK	DB01363	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16197	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	activator	target	Bar-Am O (2005)	16148027	181187	1329	Rasagiline	(R)-Indan-1-yl-prop-2-ynyl-amine|(1R)-N-Propargylindan-1-amine|RAS|(R)-N-2-Propynyl-1-indanamine	apo-rasagiline|teva-rasagiline	DRUGBANK	DB01367	C12H13N	small molecule	N04BD02	136236-51-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUOKEQAAGRXIBM-GFCCVEGCSA-N
16198	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	activator	target	Youdim MB (2001)	12043833	181186	1329	Rasagiline	(R)-Indan-1-yl-prop-2-ynyl-amine|(1R)-N-Propargylindan-1-amine|RAS|(R)-N-2-Propynyl-1-indanamine	apo-rasagiline|teva-rasagiline	DRUGBANK	DB01367	C12H13N	small molecule	N04BD02	136236-51-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUOKEQAAGRXIBM-GFCCVEGCSA-N
16199	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	activator	target	Maruyama W (2002)	12200198	181185	1329	Rasagiline	(R)-Indan-1-yl-prop-2-ynyl-amine|(1R)-N-Propargylindan-1-amine|RAS|(R)-N-2-Propynyl-1-indanamine	apo-rasagiline|teva-rasagiline	DRUGBANK	DB01367	C12H13N	small molecule	N04BD02	136236-51-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUOKEQAAGRXIBM-GFCCVEGCSA-N
16200	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	activator	target	Youdim MB (2003)	14555244	181184	1329	Rasagiline	(R)-Indan-1-yl-prop-2-ynyl-amine|(1R)-N-Propargylindan-1-amine|RAS|(R)-N-2-Propynyl-1-indanamine	apo-rasagiline|teva-rasagiline	DRUGBANK	DB01367	C12H13N	small molecule	N04BD02	136236-51-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUOKEQAAGRXIBM-GFCCVEGCSA-N
16201	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	activator	target	Akao Y (2002)	12057839	181183	1329	Rasagiline	(R)-Indan-1-yl-prop-2-ynyl-amine|(1R)-N-Propargylindan-1-amine|RAS|(R)-N-2-Propynyl-1-indanamine	apo-rasagiline|teva-rasagiline	DRUGBANK	DB01367	C12H13N	small molecule	N04BD02	136236-51-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUOKEQAAGRXIBM-GFCCVEGCSA-N
16489	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	Kim SJ (2007)	17436372	181309	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16490	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	Kim DH (2003)	14642426	181310	1353	Ginseng	-	ginsana cap 100mg|siberian gin	DRUGBANK	DB01404	-	small molecule	-	50647-08-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
16495	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Fujimoto J (1995)	7540578	181316	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16496	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Snyder BW (1990)	2326286	181314	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16497	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sanfilippo JS (1985)	4039467	181315	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16498	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	1355	Danazol	Cyclomen|Danazolum|Danocrine	cyclomen|danazol	DRUGBANK	DB01406	C22H27NO2	small molecule	G03XA01	17230-88-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POZRVZJJTULAOH-LHZXLZLDSA-N
16562	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	unknown	target	Ichiyama T (2003)	12801316	181363	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16563	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	unknown	target	Tomari S (2003)	12801315	181364	1360	Pranlukast	ONO-RS 411	-	DRUGBANK	DB01411	C27H23N5O4	small molecule	R03DC02	103177-37-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBQKINXMPLXUET-UHFFFAOYSA-N
16656	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Csaba G (1996)	8820988	181410	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16657	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Yuri T (2007)	17203775	175786	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16658	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Montero Girard G (2007)	17341305	175787	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16659	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Kumar AS (2007)	17103262	175785	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16660	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Ghebeh H (2007)	17415709	175788	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16661	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lessey BA (2006)	17118173	175789	1379	Allylestrenol	Perselin|Allyloestrenol|Allyl estrenol	-	DRUGBANK	DB01431	C21H32O	small molecule	G03DC01	432-60-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATXHVCQZZJYMCF-XUDSTZEESA-N
16702	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Sulzer D (2005)	15955613	174152	1390	MMDA	3-Methoxy-4,5-methylenedioxyphenylisopropylamine|5-Methoxy-3,4-methylenedioxyamphetamine|3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine|Amphetamine, 3,4-methylenedioxy-5-methoxy|(+-)-mmda|3-METHOXY-METHYLENEDIOXYAMPHETAMINE	-	DRUGBANK	DB01442	C11H15NO3	small molecule	-	13674-05-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQYUWUKDEVZFDB-UHFFFAOYSA-N
16766	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Green AL (1980)	6103055	181444	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
16767	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Ask AL (1983)	6646243	181443	1418	4-Methoxyamphetamine	Paramethoxyamphetamine|(2RS)-1-(4-methoxyphenyl)propan-2-amine|P-methoxyamfetamine|P-methoxyamphetamine|4-methoxyamfetamine|Formoterol fumarate related compound G|D,L-p-methoxyamphetamine	-	DRUGBANK	DB01472	C10H15NO	small molecule	-	64-13-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEGYEDYHPHMHGK-UHFFFAOYSA-N
17052	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Ulus IH (2000)	10799660	174228	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17053	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Sulzer D (2005)	15955613	174152	1517	Methamphetamine	d-deoxyephedrine|Mtamftamine|(S)-N,-dimethylbenzeneethanamine|(S)-N,alpha-Dimethylbenzeneethanamine|(S)-N,-dimethylbenzeneethanamine|Methamphetamine|(+)-(S)-N--dimethylphenethylamine|d-phenylisopropylmethylamine|Methamphetaminum|d-N-methylamphetamine|Metamfetamine|(+)-(S)-N-alpha-Dimethylphenethylamine|Metamfetaminum|d-1-phenyl-2-methylaminopropane|Dextromethamphetamine|Metanfetamina|methyl--phenylisopropylamine|Methyl-beta-phenylisopropylamine|d-desoxyephedrine|(AlphaS)-N,alpha-dimethylbenzeneethanamine	desoxyn|methamphetamine hydroc	DRUGBANK	DB01577	C10H15N	small molecule	N06BA03	537-46-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MYWUZJCMWCOHBA-VIFPVBQESA-N
17203	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17204	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Rostaing L (2010)	20155724	181558	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17205	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	George S (2009)	19774211	181559	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17206	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Ettenger R (2008)	18466433	181554	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17207	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Coppin C (2010)	20531964	181555	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17208	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Albert S (2010)	20569080	181556	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17209	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Teachey DT (2009)	19344392	181557	1529	Everolimus	40-O-(2-hydroxyethyl)-rapamycin	afinitor|afinitor disperz|zort	DRUGBANK	DB01590	C53H83NO14	small molecule	L04AA18|L01XE10	159351-69-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKVAMNSJSFKALM-GKUWKFKPSA-N
17328	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	antagonist	target	Trevani AS (2003)	14579285	177266	1549	Hydroxychloroquine	7-chloro-4-[4-(N-Ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline|7-chloro-4-(4-(N-Ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline|Hydroxychloroquinum|Hidroxicloroquina|Oxichloroquine|Oxichlorochine|2-((4-((7-chloro-4-Quinolyl)amino)pentyl)ethylamino)ethanol|(+-)-Hydroxychloroquine|2-(N-(4-(7-Chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol|7-chloro-4-(4-(Ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline|NSC4375|7-chloro-4-[5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline|()-hydroxychloroquine|Polirreumin	pms-hydroxychloroquine|apo-hyd	DRUGBANK	DB01611	C18H26ClN3O	small molecule	P01BA02	118-42-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSMGPRMXLTPCZ-UHFFFAOYSA-N
17329	119902	54106	UNQ5798/PRO19605	TLR9	CD289	9606	Homo sapiens	antagonist	target	Sun S (2007)	18220957	181586	1549	Hydroxychloroquine	7-chloro-4-[4-(N-Ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline|7-chloro-4-(4-(N-Ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline|Hydroxychloroquinum|Hidroxicloroquina|Oxichloroquine|Oxichlorochine|2-((4-((7-chloro-4-Quinolyl)amino)pentyl)ethylamino)ethanol|(+-)-Hydroxychloroquine|2-(N-(4-(7-Chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol|7-chloro-4-(4-(Ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline|NSC4375|7-chloro-4-[5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline|()-hydroxychloroquine|Polirreumin	pms-hydroxychloroquine|apo-hyd	DRUGBANK	DB01611	C18H26ClN3O	small molecule	P01BA02	118-42-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSMGPRMXLTPCZ-UHFFFAOYSA-N
17443	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Patkar AA (2006)	16641841	179836	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17444	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Baker GB (2007)	17823646	179831	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17445	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Lee KC (2007)	19300583	179829	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17446	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Azzaro AJ (2007)	17715422	179828	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17447	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Murphy DL (1998)	9564606	181613	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17448	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Fuentes JA (1979)	477738	181612	1563	Pargyline	Eutonyl|Pargyline|Eutron	-	DRUGBANK	DB01626	C11H13N	small molecule	C02KC01|C02LL01	555-57-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DPWPWRLQFGFJFI-UHFFFAOYSA-N
17457	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1567	SC-74020	-	-	DRUGBANK	DB01630	C29H42N4O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJNCFXPJICILOK-HHHXNRCGSA-N
17458	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1567	SC-74020	-	-	DRUGBANK	DB01630	C29H42N4O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJNCFXPJICILOK-HHHXNRCGSA-N
17494	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1582	Genistein	Genisterin|5,7,4'-Trihydroxyisoflavone|4',5, 7-Trihydroxyisoflavone|Genisteol	-	DRUGBANK	DB01645	C15H10O5	small molecule	-	446-72-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TZBJGXHYKVUXJN-UHFFFAOYSA-N
17552	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1614	RU84687	N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide	-	DRUGBANK	DB01678	C31H34N3O8P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SAFPHFWYRLLBFO-IZLXSDGUSA-N
17631	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	binder	target	Chen F (2005)	15994348	181621	1643	Prasterone	Dehydroandrosterone|3-hydroxyandrost-5-en-17-one|Dehydroepiandrosterone|Dehydroisoandrosterone|5-dehydroepiandrosterone|3beta-hydroxyandrost-5-en-17-one|3-beta-Hydroxy-5-androsten-17-one|5-DHEA|DHEA	prastera	DRUGBANK	DB01708	C19H28O2	small molecule	A14AA07|G03EA03	53-43-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMGSKLZLMKYGDP-USOAJAOKSA-N
17706	109512	3276	-	PRMT1	ANM1|HCP1|HRMT1L2|IR1B4	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1686	S-Adenosyl-L-Homocysteine	-	-	DRUGBANK	DB01752	C14H20N6O5S	small molecule	-	979-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZJUKTBDSGOFHSH-SRMDEQNCSA-N
17734	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17735	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1694	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	-	-	DRUGBANK	DB01761	C28H29F3N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QICPQLFMWYQJGX-SFHVURJKSA-N
17741	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1698	(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid	-	-	DRUGBANK	DB01765	C17H12N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	INSBKYCYLCEBOD-UHFFFAOYSA-N
17742	111317	5300	-	PIN1	DOD|UBL5	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1699	Beta-(2-Naphthyl)-Alanine	-	-	DRUGBANK	DB01766	C13H13NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPZXHKDZASGCLU-LBPRGKRZSA-N
17756	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17757	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17758	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17759	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17761	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1705	3-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-Dione	-	-	DRUGBANK	DB01772	C22H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPGZQOOZHIEPJW-HNNXBMFYSA-N
17762	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1705	3-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-Dione	-	-	DRUGBANK	DB01772	C22H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPGZQOOZHIEPJW-HNNXBMFYSA-N
17763	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1705	3-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-Dione	-	-	DRUGBANK	DB01772	C22H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPGZQOOZHIEPJW-HNNXBMFYSA-N
17777	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1714	2,6-Dihydroanthra/1,9-Cd/Pyrazol-6-One	-	-	DRUGBANK	DB01782	C14H8N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ACPOUJIDANTYHO-UHFFFAOYSA-N
17790	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1721	Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate	-	-	DRUGBANK	DB01790	C10H12N5O5PS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMPNJFHAPJOHPP-BTQOAJACSA-N
17791	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1721	Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate	-	-	DRUGBANK	DB01790	C10H12N5O5PS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMPNJFHAPJOHPP-BTQOAJACSA-N
17792	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1721	Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate	-	-	DRUGBANK	DB01790	C10H12N5O5PS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMPNJFHAPJOHPP-BTQOAJACSA-N
17799	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1724	I-5	-	-	DRUGBANK	DB01793	C17H10Cl2N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONVZFCHLOZUXRP-UHFFFAOYSA-N
17800	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1724	I-5	-	-	DRUGBANK	DB01793	C17H10Cl2N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONVZFCHLOZUXRP-UHFFFAOYSA-N
17801	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1724	I-5	-	-	DRUGBANK	DB01793	C17H10Cl2N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ONVZFCHLOZUXRP-UHFFFAOYSA-N
17814	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17815	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17816	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1737	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	-	-	DRUGBANK	DB01807	C20H21ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEGHHVFLTANTIZ-PTGBLXJZSA-N
17958	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1793	Inositol 1,3,4,5-Tetrakisphosphate	-	-	DRUGBANK	DB01863	C6H16O18P4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIPFCGZLFXVXBG-ZIQZFLOESA-N
17959	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1793	Inositol 1,3,4,5-Tetrakisphosphate	-	-	DRUGBANK	DB01863	C6H16O18P4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIPFCGZLFXVXBG-ZIQZFLOESA-N
17979	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1796	RU79256	-	-	DRUGBANK	DB01866	C8H8O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USNMCXDGQQVYSW-SSDOTTSWSA-N
18017	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18018	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18029	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1820	N6-Benzyl Adenosine-5'-Diphosphate	-	-	DRUGBANK	DB01893	C17H21N5O10P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MRHGMAGSDAQUFH-HVOFVXBASA-N
18030	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1820	N6-Benzyl Adenosine-5'-Diphosphate	-	-	DRUGBANK	DB01893	C17H21N5O10P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MRHGMAGSDAQUFH-HVOFVXBASA-N
18048	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1834	RU85493	-	-	DRUGBANK	DB01908	C32H36N3O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWEWSHNGVWABKG-SXOMAYOGSA-N
18049	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1834	RU85493	-	-	DRUGBANK	DB01908	C32H36N3O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWEWSHNGVWABKG-SXOMAYOGSA-N
18050	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1834	RU85493	-	-	DRUGBANK	DB01908	C32H36N3O9P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWEWSHNGVWABKG-SXOMAYOGSA-N
18075	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1844	Pentanal	-	-	DRUGBANK	DB01919	C5H10O	small molecule	-	110-62-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGBOYTHUEUWSSQ-UHFFFAOYSA-N
18076	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1844	Pentanal	-	-	DRUGBANK	DB01919	C5H10O	small molecule	-	110-62-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGBOYTHUEUWSSQ-UHFFFAOYSA-N
18077	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1844	Pentanal	-	-	DRUGBANK	DB01919	C5H10O	small molecule	-	110-62-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGBOYTHUEUWSSQ-UHFFFAOYSA-N
18100	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1865	Balanol Analog 2	-	-	DRUGBANK	DB01940	C27H26N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQLYTJZXRRDERK-LADGPHEKSA-N
18101	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1865	Balanol Analog 2	-	-	DRUGBANK	DB01940	C27H26N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQLYTJZXRRDERK-LADGPHEKSA-N
18102	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1865	Balanol Analog 2	-	-	DRUGBANK	DB01940	C27H26N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQLYTJZXRRDERK-LADGPHEKSA-N
18138	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1871	RU78262	-	-	DRUGBANK	DB01947	C7H7O5P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BYNSFVCWJXZPOW-UHFFFAOYSA-N
18139	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18140	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1872	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	-	-	DRUGBANK	DB01948	C26H22Cl2F2N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXIYTVJEIXMAQF-UHFFFAOYSA-N
18141	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1873	2-Amino-N,3,3-Trimethylbutanamide	-	-	DRUGBANK	DB01949	C7H16N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPKJNEIOHOEWLO-RXMQYKEDSA-N
18142	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1873	2-Amino-N,3,3-Trimethylbutanamide	-	-	DRUGBANK	DB01949	C7H16N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPKJNEIOHOEWLO-RXMQYKEDSA-N
18143	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1874	N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)Urea	-	-	DRUGBANK	DB01950	C12H12N4O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAEMHJKFIIIULI-UHFFFAOYSA-N
18144	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1874	N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)Urea	-	-	DRUGBANK	DB01950	C12H12N4O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAEMHJKFIIIULI-UHFFFAOYSA-N
18145	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1874	N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)Urea	-	-	DRUGBANK	DB01950	C12H12N4O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAEMHJKFIIIULI-UHFFFAOYSA-N
18147	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18148	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1877	Inhibitor of P38 Kinase	-	-	DRUGBANK	DB01953	C15H14N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UUEYCHLWAOBOHG-UHFFFAOYSA-N
18185	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1886	Phosphonotyrosine	-	-	DRUGBANK	DB01962	C9H12NO6P	small molecule	-	21820-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCWXELXMIBXGTH-QMMMGPOBSA-N
18186	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1886	Phosphonotyrosine	-	-	DRUGBANK	DB01962	C9H12NO6P	small molecule	-	21820-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DCWXELXMIBXGTH-QMMMGPOBSA-N
18224	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1896	Guanosine-5'-Monophosphate	-	-	DRUGBANK	DB01972	C10H14N5O8P	small molecule	-	85-32-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RQFCJASXJCIDSX-BZKDHIKHSA-N
18225	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1896	Guanosine-5'-Monophosphate	-	-	DRUGBANK	DB01972	C10H14N5O8P	small molecule	-	85-32-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RQFCJASXJCIDSX-BZKDHIKHSA-N
18226	108086	1742	-	DLG4	PSD95|SAP-90|SAP90	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1896	Guanosine-5'-Monophosphate	-	-	DRUGBANK	DB01972	C10H14N5O8P	small molecule	-	85-32-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RQFCJASXJCIDSX-BZKDHIKHSA-N
18241	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18242	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1912	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	-	-	DRUGBANK	DB01988	C30H27N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WFSFNKVFXLIZIY-MHZLTWQESA-N
18259	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18260	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18261	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18284	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18285	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1920	3-Methylpyridine	-	-	DRUGBANK	DB01996	C6H7N	small molecule	-	108-99-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITQTTZVARXURQS-UHFFFAOYSA-N
18330	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18331	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18336	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18337	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18390	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18391	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18392	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18404	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1971	2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide	-	-	DRUGBANK	DB02049	C19H20ClNO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QOPFTBAEAJQKSY-UHFFFAOYSA-N
18405	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18406	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18407	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18409	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18410	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18411	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18456	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18457	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18458	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1991	WAY-151693	n-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide	-	DRUGBANK	DB02071	C21H21N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AINJYWXKBKRQSX-UHFFFAOYSA-N
18510	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18511	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18512	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18513	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18568	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18569	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18573	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18621	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2069	K-252a	-	-	DRUGBANK	DB02152	C27H21N3O5	small molecule	-	97161-97-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KOZFSFOOLUUIGY-SOLYNIJKSA-N
18636	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2072	Balanol Analog 8	-	-	DRUGBANK	DB02155	C32H36N2O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XVLMXAUKCDSMMW-WBZRNCBQSA-N
18637	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2072	Balanol Analog 8	-	-	DRUGBANK	DB02155	C32H36N2O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XVLMXAUKCDSMMW-WBZRNCBQSA-N
18638	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2072	Balanol Analog 8	-	-	DRUGBANK	DB02155	C32H36N2O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XVLMXAUKCDSMMW-WBZRNCBQSA-N
18660	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2086	1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One	-	-	DRUGBANK	DB02170	C13H7NO6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOHCDJRFYXKEQW-UHFFFAOYSA-N
18663	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2091	Malonic acid	Propanedioic acid|Malonate	-	DRUGBANK	DB02175	C3H4O4	small molecule	-	141-82-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFOBLEOULBTSOW-UHFFFAOYSA-N
18664	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2091	Malonic acid	Propanedioic acid|Malonate	-	DRUGBANK	DB02175	C3H4O4	small molecule	-	141-82-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFOBLEOULBTSOW-UHFFFAOYSA-N
18665	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2091	Malonic acid	Propanedioic acid|Malonate	-	DRUGBANK	DB02175	C3H4O4	small molecule	-	141-82-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OFOBLEOULBTSOW-UHFFFAOYSA-N
18697	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18698	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18699	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2111	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	-	-	DRUGBANK	DB02195	C18H12FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSMYZLKEZDYVPI-UHFFFAOYSA-N
18713	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18714	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18715	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18734	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18735	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18736	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2123	Hexane-1,6-Diol	-	-	DRUGBANK	DB02210	C6H14O2	small molecule	-	629-11-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXMIOPMDWAUFGU-UHFFFAOYSA-N
18864	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18865	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18866	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2186	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	-	-	DRUGBANK	DB02277	C15H19ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FWIJKWMXNHRSRO-UHFFFAOYSA-N
18889	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
18890	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
18922	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2222	Cyclic Guanosine Monophosphate	Guanosine-3',5'-monophosphate	-	DRUGBANK	DB02315	C10H12N5O7P	small molecule	-	7665-99-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOOGRGPOEVQQDX-KHLHZJAASA-N
18923	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2222	Cyclic Guanosine Monophosphate	Guanosine-3',5'-monophosphate	-	DRUGBANK	DB02315	C10H12N5O7P	small molecule	-	7665-99-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOOGRGPOEVQQDX-KHLHZJAASA-N
18924	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2222	Cyclic Guanosine Monophosphate	Guanosine-3',5'-monophosphate	-	DRUGBANK	DB02315	C10H12N5O7P	small molecule	-	7665-99-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOOGRGPOEVQQDX-KHLHZJAASA-N
18964	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2241	RU83876	-	-	DRUGBANK	DB02336	C30H35N3O9P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCMLXBUNHNAMNH-FTJBHMTQSA-N
18965	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2241	RU83876	-	-	DRUGBANK	DB02336	C30H35N3O9P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCMLXBUNHNAMNH-FTJBHMTQSA-N
18966	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2241	RU83876	-	-	DRUGBANK	DB02336	C30H35N3O9P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCMLXBUNHNAMNH-FTJBHMTQSA-N
18985	109338	3091	-	HIF1A	HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78	9606	Homo sapiens	unknown	target	Dai Y (2007)	17498737	181627	2247	2-Methoxyestradiol	2-Hydroxyestradol 2-methyl ether|2-MeOE2|2-methoxy-17beta-estradiol|2ME2|2-methoxyestra-1(10),2,4-triene-3,17-diol|2-Hydroxyestradiol 2-methyl ether|ESM|2-Methoxyestradiol-17beta	-	DRUGBANK	DB02342	C19H26O3	small molecule	-	362-07-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CQOQDQWUFQDJMK-WRWXEFHESA-N
18986	109338	3091	-	HIF1A	HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78	9606	Homo sapiens	unknown	target	Zhou D (2008)	17716391	181628	2247	2-Methoxyestradiol	2-Hydroxyestradol 2-methyl ether|2-MeOE2|2-methoxy-17beta-estradiol|2ME2|2-methoxyestra-1(10),2,4-triene-3,17-diol|2-Hydroxyestradiol 2-methyl ether|ESM|2-Methoxyestradiol-17beta	-	DRUGBANK	DB02342	C19H26O3	small molecule	-	362-07-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CQOQDQWUFQDJMK-WRWXEFHESA-N
19012	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19013	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19014	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2257	3-(Benzyloxy)Pyridin-2-Amine	-	-	DRUGBANK	DB02352	C12H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMCBWICNRJLKKM-UHFFFAOYSA-N
19097	109678	3456	RP11-113D19.1	IFNB1	IFB|IFF|IFNB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2284	Beta-D-Glucose	Glucose, beta-D-|Glucoside|beta-D-glucopyranose|Beta-D-glucose, anhydrous|Glucose, beta-D|Beta-D-glucose anhydrous	-	DRUGBANK	DB02379	C6H12O6	small molecule	-	492-61-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZGKKKJIJFFOK-VFUOTHLCSA-N
19098	109678	3456	RP11-113D19.1	IFNB1	IFB|IFF|IFNB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2284	Beta-D-Glucose	Glucose, beta-D-|Glucoside|beta-D-glucopyranose|Beta-D-glucose, anhydrous|Glucose, beta-D|Beta-D-glucose anhydrous	-	DRUGBANK	DB02379	C6H12O6	small molecule	-	492-61-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZGKKKJIJFFOK-VFUOTHLCSA-N
19154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19157	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19194	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2335	RU90395	-	-	DRUGBANK	DB02432	C35H36FN3O9	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLAUERCSKPFGD-FQLXRVMXSA-N
19195	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2335	RU90395	-	-	DRUGBANK	DB02432	C35H36FN3O9	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLAUERCSKPFGD-FQLXRVMXSA-N
19196	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2335	RU90395	-	-	DRUGBANK	DB02432	C35H36FN3O9	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLAUERCSKPFGD-FQLXRVMXSA-N
19284	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19285	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19286	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19292	111554	5567	RP11-82H13.1	PRKACB	PKA C-beta|PKACB	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19293	111554	5567	RP11-82H13.1	PRKACB	PKA C-beta|PKACB	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19294	111554	5567	RP11-82H13.1	PRKACB	PKA C-beta|PKACB	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19295	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19296	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19297	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19298	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19299	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19304	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2381	Etheno-Nad	-	-	DRUGBANK	DB02483	C17H23N5O14P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LWAISUABIKYXTN-BVNNLCGGSA-N
19305	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2381	Etheno-Nad	-	-	DRUGBANK	DB02483	C17H23N5O14P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LWAISUABIKYXTN-BVNNLCGGSA-N
19306	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2381	Etheno-Nad	-	-	DRUGBANK	DB02483	C17H23N5O14P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LWAISUABIKYXTN-BVNNLCGGSA-N
19361	111507	5515	-	PPP2CA	PP2Ac|PP2CA|PP2Calpha|RP-C	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2403	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	-	-	DRUGBANK	DB02506	C20H33NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SWTFXINHZPXNOX-DZBHQSCQSA-N
19401	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2424	Cyclic Adenosine Monophosphate	cAMP|3',5'-Cyclic AMP|Cyclic adenylic acid|3'-5'-cyclic adenosine monophosphate|Cyclic AMP	-	DRUGBANK	DB02527	C10H12N5O6P	small molecule	-	60-92-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IVOMOUWHDPKRLL-ASCDQALMSA-N
19402	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2424	Cyclic Adenosine Monophosphate	cAMP|3',5'-Cyclic AMP|Cyclic adenylic acid|3'-5'-cyclic adenosine monophosphate|Cyclic AMP	-	DRUGBANK	DB02527	C10H12N5O6P	small molecule	-	60-92-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IVOMOUWHDPKRLL-ASCDQALMSA-N
19403	111559	5573	-	PRKAR1A	ACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2424	Cyclic Adenosine Monophosphate	cAMP|3',5'-Cyclic AMP|Cyclic adenylic acid|3'-5'-cyclic adenosine monophosphate|Cyclic AMP	-	DRUGBANK	DB02527	C10H12N5O6P	small molecule	-	60-92-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IVOMOUWHDPKRLL-ASCDQALMSA-N
19418	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19419	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19420	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19433	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Xu WS (2007)	17694093	181632	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
19436	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
19437	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	inhibitor	target	Xu WS (2007)	17694093	181632	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
19526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19527	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19528	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19540	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2504	Balanol Analog 1	-	-	DRUGBANK	DB02611	C20H22N2O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FZJQHARRQUNVGZ-QZTJIDSGSA-N
19548	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2507	Compound 19	-	-	DRUGBANK	DB02615	C27H29NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZOOIPXOYYJULJ-OALGXETFSA-N
19549	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2507	Compound 19	-	-	DRUGBANK	DB02615	C27H29NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZOOIPXOYYJULJ-OALGXETFSA-N
19556	109189	2934	RP11-477J21.1	GSN	ADF|AGEL	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2513	Latrunculin A	LAT-A|LatA|(+)-latrunculin A|(4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one	-	DRUGBANK	DB02621	C22H31NO5S	small molecule	-	76343-93-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DDVBPZROPPMBLW-IZGXTMSKSA-N
19620	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19621	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19622	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19725	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19726	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2586	Hydroxyaminovaline	-	-	DRUGBANK	DB02697	C5H12N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USSBBYRBOWZYSB-SCSAIBSYSA-N
19732	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
19733	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
19734	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
19744	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	2597	Resveratrol	(E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol|trans-3,4',5-trihydroxystilbene|(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol|3,4',5-Stilbenetriol|3,4',5-Trihydroxystilbene|(E)-5-(p-Hydroxystyryl)resorcinol|3,4',5-trihydroxy-stilbene|(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol|(E)-resveratrol	co-veratrol	DRUGBANK	DB02709	C14H12O3	small molecule	-	501-36-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUKBXSAWLPMMSZ-OWOJBTEDSA-N
19756	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2603	Compound 18	-	-	DRUGBANK	DB02715	C27H29NO4S	small molecule	-	31112-66-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZOOIPXOYYJULJ-OALGXETFSA-N
19757	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2603	Compound 18	-	-	DRUGBANK	DB02715	C27H29NO4S	small molecule	-	31112-66-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UZOOIPXOYYJULJ-OALGXETFSA-N
19812	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19814	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19815	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19816	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19817	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19818	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19871	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2647	RU79072	-	-	DRUGBANK	DB02762	C10H7N2O4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NQLPTOOPFMPCHQ-UHFFFAOYSA-N
19882	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2652	3-Hydroxy-Myristic Acid	-	-	DRUGBANK	DB02767	C14H28O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ATRNZOYKSNPPBF-CYBMUJFWSA-N
19986	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19987	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19988	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19989	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
20061	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20062	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20063	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2755	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	-	-	DRUGBANK	DB02873	C24H20Cl2F2N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YAWZIQKDHQIHOS-UHFFFAOYSA-N
20095	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20096	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20112	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2788	RU78783	-	-	DRUGBANK	DB02908	C7H10O6P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRLTXWJJMCIUNT-UHFFFAOYSA-N
20113	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2788	RU78783	-	-	DRUGBANK	DB02908	C7H10O6P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRLTXWJJMCIUNT-UHFFFAOYSA-N
20114	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2788	RU78783	-	-	DRUGBANK	DB02908	C7H10O6P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FRLTXWJJMCIUNT-UHFFFAOYSA-N
20127	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20128	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20129	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20130	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20185	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20189	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20200	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20201	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20202	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20216	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20217	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20233	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20234	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20235	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2861	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB02984	C17H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUSDVOSGGMBSMK-UHFFFAOYSA-N
20323	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20324	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20331	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2897	1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine	-	-	DRUGBANK	DB03023	C15H17ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PBBRWFOVCUAONR-UHFFFAOYSA-O
20359	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20360	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2906	1-Methyloxy-4-Sulfone-Benzene	-	-	DRUGBANK	DB03033	C7H8O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUNSZADDFLWFOL-UHFFFAOYSA-N
20361	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2908	1,8-Di-Hydroxy-4-Nitro-Anthraquinone	-	-	DRUGBANK	DB03035	C14H7NO6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIYCICFDXLNQPV-UHFFFAOYSA-N
20375	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20376	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
20429	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2949	PASBN	-	-	DRUGBANK	DB03078	C14H13O5P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWDTUFYQEUEVQD-UHFFFAOYSA-N
20456	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20457	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20458	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2959	Pyroglutamic Acid	-	-	DRUGBANK	DB03088	C5H7NO3	small molecule	-	98-79-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ODHCTXKNWHHXJC-GSVOUGTGSA-N
20497	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2975	RU82129	-	-	DRUGBANK	DB03104	C33H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKMPOVPTYDXGEC-HMIUAYQISA-N
20498	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2975	RU82129	-	-	DRUGBANK	DB03104	C33H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKMPOVPTYDXGEC-HMIUAYQISA-N
20499	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2975	RU82129	-	-	DRUGBANK	DB03104	C33H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKMPOVPTYDXGEC-HMIUAYQISA-N
20505	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20506	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2981	2-Chlorophenol	-	-	DRUGBANK	DB03110	C6H5ClO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ISPYQTSUDJAMAB-UHFFFAOYSA-N
20509	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2985	PAS219	-	-	DRUGBANK	DB03114	C14H19O5P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBEVTZVQKMYQPM-UHFFFAOYSA-N
20510	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2986	5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide	-	-	DRUGBANK	DB03115	C16H13BrF3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSSGBYXSKOLAM-MRVPVSSYSA-N
20511	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2986	5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide	-	-	DRUGBANK	DB03115	C16H13BrF3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXSSGBYXSKOLAM-MRVPVSSYSA-N
20525	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20526	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20527	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2993	5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid	-	-	DRUGBANK	DB03124	C20H20N2O9S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBAHOXPDTNUYCX-INIZCTEOSA-N
20540	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2996	Benzamidine	-	-	DRUGBANK	DB03127	C7H9N2	small molecule	-	618-39-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PXXJHWLDUBFPOL-UHFFFAOYSA-O
20541	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2996	Benzamidine	-	-	DRUGBANK	DB03127	C7H9N2	small molecule	-	618-39-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PXXJHWLDUBFPOL-UHFFFAOYSA-O
20542	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2996	Benzamidine	-	-	DRUGBANK	DB03127	C7H9N2	small molecule	-	618-39-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PXXJHWLDUBFPOL-UHFFFAOYSA-O
20601	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3015	Flavin adenine dinucleotide	Riboflavin 5'-adenosine diphosphate|Adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate]|FLAVIN-adenine dinucleotide|FAD|Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine|Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine|Flavin adenine dinucleotide	-	DRUGBANK	DB03147	C27H33N9O15P2	small molecule	-	146-14-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWWQXMAJTJZDQX-UYBVJOGSSA-N
20602	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3015	Flavin adenine dinucleotide	Riboflavin 5'-adenosine diphosphate|Adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate]|FLAVIN-adenine dinucleotide|FAD|Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine|Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine|Flavin adenine dinucleotide	-	DRUGBANK	DB03147	C27H33N9O15P2	small molecule	-	146-14-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWWQXMAJTJZDQX-UYBVJOGSSA-N
20603	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3015	Flavin adenine dinucleotide	Riboflavin 5'-adenosine diphosphate|Adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate]|FLAVIN-adenine dinucleotide|FAD|Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine|Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine|Flavin adenine dinucleotide	-	DRUGBANK	DB03147	C27H33N9O15P2	small molecule	-	146-14-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VWWQXMAJTJZDQX-UYBVJOGSSA-N
20769	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3085	DPI59	-	-	DRUGBANK	DB03217	C11H11O4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AXIBZLYWMBUYRV-NSHDSACASA-N
20786	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20787	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20788	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3094	Trifluoroethanol	-	-	DRUGBANK	DB03226	C2H3F3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQDFWAXVIIEBN-UHFFFAOYSA-N
20874	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3134	RU82197	-	-	DRUGBANK	DB03268	C32H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WKTQBTSOHBKBRW-WDYNHAJCSA-N
20875	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3134	RU82197	-	-	DRUGBANK	DB03268	C32H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WKTQBTSOHBKBRW-WDYNHAJCSA-N
20876	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3134	RU82197	-	-	DRUGBANK	DB03268	C32H33N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WKTQBTSOHBKBRW-WDYNHAJCSA-N
20926	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3163	Phenylphosphate	-	-	DRUGBANK	DB03298	C6H7O4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMPQUABWPXYYSH-UHFFFAOYSA-N
20927	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3163	Phenylphosphate	-	-	DRUGBANK	DB03298	C6H7O4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMPQUABWPXYYSH-UHFFFAOYSA-N
20928	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3163	Phenylphosphate	-	-	DRUGBANK	DB03298	C6H7O4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMPQUABWPXYYSH-UHFFFAOYSA-N
20932	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3171	RU78300	-	-	DRUGBANK	DB03306	C8H9O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CGEZBCISRKFHLZ-UHFFFAOYSA-N
20933	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20934	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20935	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
21040	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21041	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21042	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21057	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3235	3,5-Diiodotyrosine	-	-	DRUGBANK	DB03374	C9H9I2NO3	small molecule	-	300-39-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NYPYHUZRZVSYKL-ZETCQYMHSA-N
21186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21189	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21190	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21244	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3300	(3e)-6'-Bromo-2,3'-Biindole-2',3(1h,1'h)-Dione 3-Oxime	-	-	DRUGBANK	DB03444	C16H10BrN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DDLZLOKCJHBUHD-WAVHTBQISA-N
21384	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21385	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21386	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21391	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21393	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21394	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21398	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21400	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21401	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Zvelebil MJ (1998)	18465538	182075	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21419	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21420	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21421	112986	7132	-	TNFRSF1A	CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3362	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One	-	-	DRUGBANK	DB03507	C21H20N4O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXGUZFZBZPPZGL-UHFFFAOYSA-N
21439	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3379	RU79073	-	-	DRUGBANK	DB03525	C9H12NO4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NSJSAHCLJYVEDM-UHFFFAOYSA-N
21535	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21536	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21537	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21553	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3439	RU82209	-	-	DRUGBANK	DB03591	C31H34F2N3O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVZDQVATAQEMCX-IZLXSDGUSA-N
21554	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3439	RU82209	-	-	DRUGBANK	DB03591	C31H34F2N3O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVZDQVATAQEMCX-IZLXSDGUSA-N
21555	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3439	RU82209	-	-	DRUGBANK	DB03591	C31H34F2N3O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVZDQVATAQEMCX-IZLXSDGUSA-N
21620	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3475	ISO24	-	-	DRUGBANK	DB03628	C9H12NO4P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KGNSYMGWPCEFDZ-UHFFFAOYSA-N
21674	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21675	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21676	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21706	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21707	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21708	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3529	2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid	-	-	DRUGBANK	DB03683	C8H15NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LFMOJNDZFCHHPV-SSDOTTSWSA-N
21781	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3556	RU85053	-	-	DRUGBANK	DB03712	C33H35N3O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEKLBQMULVLLTD-WDYNHAJCSA-N
21782	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3556	RU85053	-	-	DRUGBANK	DB03712	C33H35N3O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEKLBQMULVLLTD-WDYNHAJCSA-N
21783	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3556	RU85053	-	-	DRUGBANK	DB03712	C33H35N3O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEKLBQMULVLLTD-WDYNHAJCSA-N
21826	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21827	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21828	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21843	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3585	Compound 4-D	-	-	DRUGBANK	DB03742	C27H29NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWZNCTCQAGRUGQ-KAYWLYCHSA-N
21844	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3585	Compound 4-D	-	-	DRUGBANK	DB03742	C27H29NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWZNCTCQAGRUGQ-KAYWLYCHSA-N
21863	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21864	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21865	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3596	Tris	Tromethamine|Tris(hydroxymethyl)aminomethane|THAM	sooryehan hyo fermented sun bl	DRUGBANK	DB03754	C4H11NO3	small molecule	-	77-86-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LENZDBCJOHFCAS-UHFFFAOYSA-N
21979	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
21980	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
21985	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3641	1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol	-	-	DRUGBANK	DB03802	C29H33N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZGHFWBDHZZKWSI-GGXMVOPNSA-N
21986	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3641	1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol	-	-	DRUGBANK	DB03802	C29H33N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZGHFWBDHZZKWSI-GGXMVOPNSA-N
22039	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3666	RU78299	-	-	DRUGBANK	DB03828	C9H9O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NAYNUXXSJZLKPW-UHFFFAOYSA-N
22148	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3739	Oxalic Acid	-	-	DRUGBANK	DB03902	C2H2O4	small molecule	-	144-62-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MUBZPKHOEPUJKR-UHFFFAOYSA-N
22149	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3739	Oxalic Acid	-	-	DRUGBANK	DB03902	C2H2O4	small molecule	-	144-62-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MUBZPKHOEPUJKR-UHFFFAOYSA-N
22150	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3739	Oxalic Acid	-	-	DRUGBANK	DB03902	C2H2O4	small molecule	-	144-62-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MUBZPKHOEPUJKR-UHFFFAOYSA-N
22156	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3741	Urea	-	uramaxin|umecta mousse urea|ca	DRUGBANK	DB03904	CH4N2O	small molecule	-	57-13-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSQUKJJJFZCRTK-UHFFFAOYSA-N
22157	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3741	Urea	-	uramaxin|umecta mousse urea|ca	DRUGBANK	DB03904	CH4N2O	small molecule	-	57-13-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSQUKJJJFZCRTK-UHFFFAOYSA-N
22158	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3741	Urea	-	uramaxin|umecta mousse urea|ca	DRUGBANK	DB03904	CH4N2O	small molecule	-	57-13-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XSQUKJJJFZCRTK-UHFFFAOYSA-N
22180	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3746	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate	-	-	DRUGBANK	DB03909	C11H18N5O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UFZTZBNSLXELAL-WOIOKPISSA-N
22181	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3746	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate	-	-	DRUGBANK	DB03909	C11H18N5O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UFZTZBNSLXELAL-WOIOKPISSA-N
22182	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3746	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate	-	-	DRUGBANK	DB03909	C11H18N5O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UFZTZBNSLXELAL-WOIOKPISSA-N
22193	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3758	4-(3-Pyridin-2-Yl-1h-Pyrazol-4-Yl)Quinoline	-	-	DRUGBANK	DB03921	C17H12N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IBCXZJCWDGCXQT-UHFFFAOYSA-N
22197	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3760	5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone	-	-	DRUGBANK	DB03924	C14H10N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QVEMRPAUHFWHRV-UHFFFAOYSA-N
22224	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3776	Oxamic Acid	-	-	DRUGBANK	DB03940	C2H3NO3	small molecule	-	471-47-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SOWBFZRMHSNYGE-UHFFFAOYSA-N
22225	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3776	Oxamic Acid	-	-	DRUGBANK	DB03940	C2H3NO3	small molecule	-	471-47-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SOWBFZRMHSNYGE-UHFFFAOYSA-N
22226	110131	3939	PIG19	LDHA	GSD11|HEL-S-133P|LDH1|LDHM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3776	Oxamic Acid	-	-	DRUGBANK	DB03940	C2H3NO3	small molecule	-	471-47-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SOWBFZRMHSNYGE-UHFFFAOYSA-N
22329	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3814	4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole	-	-	DRUGBANK	DB03980	C17H16FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFEYXQGDDCDXJK-UHFFFAOYSA-N
22373	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22374	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22375	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22387	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3848	Alsterpaullone	-	-	DRUGBANK	DB04014	C16H11N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OLUKILHGKRVDCT-UHFFFAOYSA-N
22388	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3848	Alsterpaullone	-	-	DRUGBANK	DB04014	C16H11N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OLUKILHGKRVDCT-UHFFFAOYSA-N
22389	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3848	Alsterpaullone	-	-	DRUGBANK	DB04014	C16H11N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OLUKILHGKRVDCT-UHFFFAOYSA-N
22390	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3848	Alsterpaullone	-	-	DRUGBANK	DB04014	C16H11N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OLUKILHGKRVDCT-UHFFFAOYSA-N
22400	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3851	N-Methyl-N-Propargyl-3-(2,4-Dichlorophenoxy)Propylamine	-	-	DRUGBANK	DB04017	C13H15Cl2NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BTFHLQRNAMSNLC-UHFFFAOYSA-N
22489	112906	7048	-	TGFBR2	AAT3|FAA3|LDS1B|LDS2|LDS2B|MFS2|RIIC|TAAD2|TGFR-2|TGFbeta-RII	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3909	Glycerol	-	-	DRUGBANK	DB04077	C3H8O3	small molecule	A06AG04|A06AX01	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEDCQBHIVMGVHV-UHFFFAOYSA-N
22490	112906	7048	-	TGFBR2	AAT3|FAA3|LDS1B|LDS2|LDS2B|MFS2|RIIC|TAAD2|TGFR-2|TGFbeta-RII	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3909	Glycerol	-	-	DRUGBANK	DB04077	C3H8O3	small molecule	A06AG04|A06AX01	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PEDCQBHIVMGVHV-UHFFFAOYSA-N
22521	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3912	RU78191	-	-	DRUGBANK	DB04080	C9H8O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WWYDYZMNFQIYPT-UHFFFAOYSA-N
22557	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3930	Balanol	-	-	DRUGBANK	DB04098	C28H26N2O10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XYUFCXJZFZPEJD-PGRDOPGGSA-N
22558	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3930	Balanol	-	-	DRUGBANK	DB04098	C28H26N2O10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XYUFCXJZFZPEJD-PGRDOPGGSA-N
22559	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3930	Balanol	-	-	DRUGBANK	DB04098	C28H26N2O10	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XYUFCXJZFZPEJD-PGRDOPGGSA-N
22570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22644	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22645	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22646	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3968	Guanosine-5'-Triphosphate	-	-	DRUGBANK	DB04137	C10H16N5O14P3	small molecule	-	86-01-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKMLYUALXHKNFT-BZKDHIKHSA-N
22781	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22782	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22783	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22939	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22940	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
22941	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4099	Citric Acid	2-Hydroxytricarballylic acid|3-Carboxy-3-hydroxypentane-1,5-dioic acid|Citronensure	medique medi seltzer|purg-odan	DRUGBANK	DB04272	C6H8O7	small molecule	A09AB04	77-92-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKNYBCHXYNGOX-UHFFFAOYSA-N
23004	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23005	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23006	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23055	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23056	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23057	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23108	106880	387	-	RHOA	ARH12|ARHA|RHO12|RHOH12	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23109	106880	387	-	RHOA	ARH12|ARHA|RHO12|RHOH12	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23110	106880	387	-	RHOA	ARH12|ARHA|RHO12|RHOH12	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4140	Guanosine-5'-Diphosphate	-	-	DRUGBANK	DB04315	C10H15N5O11P2	small molecule	-	146-91-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QGWNDRXFNXRZMB-BZKDHIKHSA-N
23161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23162	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23163	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23164	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4163	SB220025	-	-	DRUGBANK	DB04338	C18H19FN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VSPFURGQAYMVAN-UHFFFAOYSA-N
23269	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23270	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23271	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23302	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23303	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23350	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23351	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23352	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23385	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4249	Naphthyridine Inhibitor	-	-	DRUGBANK	DB04434	C17H15N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YRBHUKMLAGQYHS-UHFFFAOYSA-N
23474	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4276	Tetrabromo-2-Benzotriazole	-	-	DRUGBANK	DB04462	C6HBr4N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OMZYUVOATZSGJY-UHFFFAOYSA-N
23475	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4276	Tetrabromo-2-Benzotriazole	-	-	DRUGBANK	DB04462	C6HBr4N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OMZYUVOATZSGJY-UHFFFAOYSA-N
23476	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4276	Tetrabromo-2-Benzotriazole	-	-	DRUGBANK	DB04462	C6HBr4N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OMZYUVOATZSGJY-UHFFFAOYSA-N
23522	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Reed CA (2005)	15846122	181889	4282	Afimoxifene	4-monohydroxytamoxifen|4-Hydroxytamoxifen|4-OHT	-	DRUGBANK	DB04468	C26H29NO2	small molecule	-	68392-35-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXUZVZSFRXZGTL-QPLCGJKRSA-N
23526	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4285	2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol	-	-	DRUGBANK	DB04471	C28H32N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMWVCTJKLAVRPB-MUUNZHRXSA-N
23527	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4285	2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol	-	-	DRUGBANK	DB04471	C28H32N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMWVCTJKLAVRPB-MUUNZHRXSA-N
23537	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4293	3-(4-Fluorophenyl)-2-(6-Methylpyridin-2-Yl)-5,6-Dihydro-4h-Pyrrolo[1,2-B]Pyrazole	-	-	DRUGBANK	DB04480	C18H16FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NBDZLUOYAAVYHF-UHFFFAOYSA-N
23545	109839	3627	-	CXCL10	C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4300	N-Methylleucine	-	-	DRUGBANK	DB04487	C7H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJODGRWDFZVTKW-ZCFIWIBFSA-N
23546	109839	3627	-	CXCL10	C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4300	N-Methylleucine	-	-	DRUGBANK	DB04487	C7H15NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJODGRWDFZVTKW-ZCFIWIBFSA-N
23564	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4308	RU81843	-	-	DRUGBANK	DB04495	C30H34N3O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGPXNASQNUOIPB-IZLXSDGUSA-N
23565	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4308	RU81843	-	-	DRUGBANK	DB04495	C30H34N3O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGPXNASQNUOIPB-IZLXSDGUSA-N
23566	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4308	RU81843	-	-	DRUGBANK	DB04495	C30H34N3O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGPXNASQNUOIPB-IZLXSDGUSA-N
23571	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4322	3-Phosphoglyceric Acid	-	-	DRUGBANK	DB04510	C3H7O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSJPPGNTCRNQQC-REOHCLBHSA-N
23572	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4322	3-Phosphoglyceric Acid	-	-	DRUGBANK	DB04510	C3H7O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSJPPGNTCRNQQC-REOHCLBHSA-N
23573	111251	5230	RP4-570L12.1	PGK1	HEL-S-68p|MIG10|PGKA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4322	3-Phosphoglyceric Acid	-	-	DRUGBANK	DB04510	C3H7O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSJPPGNTCRNQQC-REOHCLBHSA-N
23592	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23593	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23594	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23608	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4334	Phosphonoserine	-	-	DRUGBANK	DB04522	C3H8NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BZQFBWGGLXLEPQ-REOHCLBHSA-N
23609	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4334	Phosphonoserine	-	-	DRUGBANK	DB04522	C3H8NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BZQFBWGGLXLEPQ-REOHCLBHSA-N
23610	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4334	Phosphonoserine	-	-	DRUGBANK	DB04522	C3H8NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BZQFBWGGLXLEPQ-REOHCLBHSA-N
23647	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4342	S,S-(2-Hydroxyethyl)Thiocysteine	-	-	DRUGBANK	DB04530	C5H11NO3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YPUBRSXDQSFQBA-BYPYZUCNSA-N
23648	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4342	S,S-(2-Hydroxyethyl)Thiocysteine	-	-	DRUGBANK	DB04530	C5H11NO3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YPUBRSXDQSFQBA-BYPYZUCNSA-N
23649	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4342	S,S-(2-Hydroxyethyl)Thiocysteine	-	-	DRUGBANK	DB04530	C5H11NO3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YPUBRSXDQSFQBA-BYPYZUCNSA-N
23731	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	4383	Estriol	16-alpha-Hydroxyestradiol|(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol|Estriel|16-hydroxyestradiol|(16,17)-estra-1,3,5(10)-triene-3,16,17-triol|Oestriol|3,16alpha,17beta-Trihydroxy-delta(1,3,5)-estratriene|1,3,5(10)-Estratriene-3,16-alpha,17beta-triol|Trihydroxyestrin|Deuslon-a|Estriol|16alpha-hydroxyestradiol	-	DRUGBANK	DB04573	C18H24O3	small molecule	G03CA04|G03CC06	50-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PROQIPRRNZUXQM-ZXXIGWHRSA-N
23732	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	4383	Estriol	16-alpha-Hydroxyestradiol|(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol|Estriel|16-hydroxyestradiol|(16,17)-estra-1,3,5(10)-triene-3,16,17-triol|Oestriol|3,16alpha,17beta-Trihydroxy-delta(1,3,5)-estratriene|1,3,5(10)-Estratriene-3,16-alpha,17beta-triol|Trihydroxyestrin|Deuslon-a|Estriol|16alpha-hydroxyestradiol	-	DRUGBANK	DB04573	C18H24O3	small molecule	G03CA04|G03CC06	50-27-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PROQIPRRNZUXQM-ZXXIGWHRSA-N
23735	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Sasson S (1991)	2011412	177583	4384	Estrone sulfate	Estrone bisulfate|Estrone-3-sulphate|estrone sulphate|Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate|Estrone 3-sulfate|Estrone hemisulfate|Estrone hydrogen sulfate|Estrone, hydrogen sulfate	ogen .625|estropipate|ogen 2.5	DRUGBANK	DB04574	C18H22O5S	small molecule	-	481-97-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JKKFKPJIXZFSSB-CBZIJGRNSA-N
23736	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Lehnes K (2007)	17138652	178365	4384	Estrone sulfate	Estrone bisulfate|Estrone-3-sulphate|estrone sulphate|Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate|Estrone 3-sulfate|Estrone hemisulfate|Estrone hydrogen sulfate|Estrone, hydrogen sulfate	ogen .625|estropipate|ogen 2.5	DRUGBANK	DB04574	C18H22O5S	small molecule	-	481-97-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JKKFKPJIXZFSSB-CBZIJGRNSA-N
23737	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	4384	Estrone sulfate	Estrone bisulfate|Estrone-3-sulphate|estrone sulphate|Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate|Estrone 3-sulfate|Estrone hemisulfate|Estrone hydrogen sulfate|Estrone, hydrogen sulfate	ogen .625|estropipate|ogen 2.5	DRUGBANK	DB04574	C18H22O5S	small molecule	-	481-97-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JKKFKPJIXZFSSB-CBZIJGRNSA-N
23738	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Brama M (2007)	17125913	178366	4384	Estrone sulfate	Estrone bisulfate|Estrone-3-sulphate|estrone sulphate|Estra-1,3,5 (10)-triene-17-one-3-yl-sulfate|Estrone 3-sulfate|Estrone hemisulfate|Estrone hydrogen sulfate|Estrone, hydrogen sulfate	ogen .625|estropipate|ogen 2.5	DRUGBANK	DB04574	C18H22O5S	small molecule	-	481-97-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JKKFKPJIXZFSSB-CBZIJGRNSA-N
23739	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Imming P (2006)	17016423	171742	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23740	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Chen X (2002)	11752352	171740	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23741	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Overington JP (2006)	17139284	171741	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23742	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	modulator	target	Shyu C (2011)	21075131	182176	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23743	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Imming P (2006)	17016423	171742	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23744	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Chen X (2002)	11752352	171740	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23745	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Overington JP (2006)	17139284	171741	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23746	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Shyu C (2011)	21075131	182176	4385	Quinestrol	Estrovis|Eston|Estrovister|Quinestrolo|Quinestrolum|17alpha-Ethynylestradiol 3-cyclopentyl ether|Quinestrol|Quilea|Estradiol-17-beta 3-cyclopentyl ether|17-alpha-Ethinylestradiol 3-cyclopentyl ether|Estrovis 4000|ethinyl estradiol 3-cyclopentyl ether|Plestrovis	-	DRUGBANK	DB04575	C25H32O2	small molecule	-	152-43-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWZUUYSISTUNDW-VAFBSOEGSA-N
23766	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4413	5-iodotubercidin	-	-	DRUGBANK	DB04604	C11H13IN4O4	small molecule	-	24386-93-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WHSIXKUPQCKWBY-IOSLPCCCSA-N
23767	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4416	PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE	-	-	DRUGBANK	DB04607	C20H14Cl2N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQAWGIKJINAKIZ-UHFFFAOYSA-N
23786	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4438	4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE	-	-	DRUGBANK	DB04632	C24H26FN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JHHBGNIRSUTQAS-UHFFFAOYSA-N
23804	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4467	OLOMOUCINE II	-	-	DRUGBANK	DB04662	C19H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NDUVSANREQEDRE-CQSZACIVSA-N
23806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4474	TRIAZOLOPYRIMIDINE	-	-	DRUGBANK	DB04669	C17H14BrN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWBFPKPWMSWWEA-UHFFFAOYSA-O
23826	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4511	HYDROXYFASUDIL	-	-	DRUGBANK	DB04707	C14H17N3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZAVGJDAFCZAWSZ-UHFFFAOYSA-N
23836	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4520	2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE	-	-	DRUGBANK	DB04716	C18H16FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VNDWQCSOSCCWIP-UHFFFAOYSA-N
23837	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4520	2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE	-	-	DRUGBANK	DB04716	C18H16FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VNDWQCSOSCCWIP-UHFFFAOYSA-N
23839	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4520	2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE	-	-	DRUGBANK	DB04716	C18H16FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VNDWQCSOSCCWIP-UHFFFAOYSA-N
23841	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4523	DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE	-	-	DRUGBANK	DB04719	C9H7Br4N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SLPJGDQJLTYWCI-UHFFFAOYSA-N
23842	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4524	S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE	-	-	DRUGBANK	DB04720	C8H4Br4N2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZIGJZZDDPXRGTL-UHFFFAOYSA-N
23843	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4525	N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE	-	-	DRUGBANK	DB04721	C10H7Br4N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QHCZROILDUNGRT-UHFFFAOYSA-N
23864	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4554	Purvalanol A	6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine|Purv	-	DRUGBANK	DB04751	C19H25ClN6O	small molecule	-	212844-53-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PMXCMJLOPOFPBT-HNNXBMFYSA-N
23870	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4562	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE)	-	-	DRUGBANK	DB04759	C22H22N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTBUZLPQANSGGE-UHFFFAOYSA-N
23871	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4563	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE)	-	-	DRUGBANK	DB04760	C22H20F2N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYFRREJCFXFNRR-UHFFFAOYSA-N
23872	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4564	PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE]	-	-	DRUGBANK	DB04761	C18H16N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHPBWKYFMTXWAA-UHFFFAOYSA-N
23910	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4599	Triazolopyridine	-	-	DRUGBANK	DB04797	C18H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVCXRBARSPBVMC-UHFFFAOYSA-N
23926	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Hovevey-Sion D (1989)	2506486	181654	4622	Nialamide	2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid|Isonicitinic acid 2-[(2-benzylcarbamoyl)ethyl]hydrazide|2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid|N-Benzyl-3-(2-isonicotinoylhydrazino)propanamide|2-(2-(Benzylcarbamoyl)ethyl)hydrazide, isonicotinic acid|Isonicotinic acid, 2-[2-(benzylcarbamoylethyl]hydrazide|Pyridine-4-carboxylic 2-[2-(benzylcarbamoyl)ethyl]hydrazide|1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine|N-benzyl-beta-(isonicotinoylhydrazine)propionamide|N-benzyl-beta-(isonicotinylhydrazino)propionamide|Isonicotinic acid, 2-[2-(benzylcarbamoyl)ethyl]hydrazide|Isonicotinic acid, 2-[2- (benzylcarbamoyl)ethyl]hydrazide|BEIH|Isonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazide|N-isonicotinyl hydrazide|N-isonicotinoyl-n'(beta-n-benzylcarboxamidoethyl)hydrazine|Isonicotinic acid, {2-[2-(benzylcarbamoyl)ethyl]hydrazide}|Isonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazide|2-[2-(Benzylcarbamoyl)ethyl]hydrazide isonicotinic acid|N-(2-(Benzylcarbamyl)ethylamino)isonicotinamide|Isonicotinic acid, {2-[2-(benzylcarbamoylethyl]hydrazide}|1-[2-(Benzylcarbamoyl)ethyl]-2-isonicotinoylhydrazine|Nialamida|Nialamidum	-	DRUGBANK	DB04820	C16H18N4O2	small molecule	N06AF02	51-12-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NOIIUHRQUVNIDD-UHFFFAOYSA-N
23929	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Egashira T (1999)	10580379	181743	4623	Nomifensine	(+-)-nomifensin|Nomifensin|2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine|(+)-nomiphensine|8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline|Nomifensina|Nomifensinum|8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisochinolin|8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline|(+-)-nomifensine|(+)-nomifensine|(R)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine	-	DRUGBANK	DB04821	C16H18N2	small molecule	N06AX04	24526-64-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXPANQJNYNUNES-UHFFFAOYSA-N
23940	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Egashira T (1996)	8842678	181710	4634	Zimelidine	(z)-zimelidine|Zimeldine|(Z)-3-(4'-Bromophenyl)-3-(3''-pyridyl)dimethylallylamine|Cis-zimelidine|(Z)-3-[1-(p-Bromophenyl)-3-(dimethylamino)propenyl]pyridine	-	DRUGBANK	DB04832	C16H17BrN2	small molecule	N06AB02	56775-88-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYPPVKRFBIWMSX-SXGWCWSVSA-N
23942	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Overington JP (2006)	17139284	171741	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
23943	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Imming P (2006)	17016423	171742	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
23944	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
23945	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Agrawal-Gamse C (2009)	19692476	182123	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
23946	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Napier C (2005)	16298345	181920	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
23947	107639	1234	-	CCR5	CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22	9606	Homo sapiens	antagonist	target	Levy JA (2009)	19098484	182094	4637	Maraviroc	-	selzentry|celsentri	DRUGBANK	DB04835	C29H41F2N5O	small molecule	J05AX09	376348-65-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSNHKUDZZFZSJB-QYOOZWMWSA-N
24039	110457	4313	-	MMP2	CLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1	9606	Homo sapiens	unknown	target	Elkin M (2000)	11099465	181766	4666	Halofuginone	Tempostatin (Collgard Biopharmaceuticals)	-	DRUGBANK	DB04866	C16H17BrClN3O3	small molecule	-	55837-20-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVASCWIMLIKXLA-YSSOQSIOSA-N
24176	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	unknown	target	Shimamoto A (2006)	16820585	181952	4730	Eritoran	-	-	DRUGBANK	DB04933	C66H126N2O19P2	small molecule	-	185955-34-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPSMYQFMCXXNPC-MFCPCZTFSA-N
24177	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	unknown	target	Kim HM (2007)	17803912	182045	4730	Eritoran	-	-	DRUGBANK	DB04933	C66H126N2O19P2	small molecule	-	185955-34-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPSMYQFMCXXNPC-MFCPCZTFSA-N
24179	112874	7015	-	TERT	CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT	9606	Homo sapiens	unknown	target	Kokhaei P (2007)	17258078	181984	4733	GV1001	-	-	DRUGBANK	DB04937	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24180	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Wurz GT (2005)	16153821	181910	4734	Ospemifene	2-(P-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol|Deamino-hydroxytoremifene|2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol|Osphena|FC-1271a|FC-1271	osphena	DRUGBANK	DB04938	C24H23ClO2	small molecule	G03XC05	128607-22-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUMKNAVTFCDUIE-VHXPQNKSSA-N
24181	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Komi J (2004)	15255284	181854	4734	Ospemifene	2-(P-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol|Deamino-hydroxytoremifene|2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol|Osphena|FC-1271a|FC-1271	osphena	DRUGBANK	DB04938	C24H23ClO2	small molecule	G03XC05	128607-22-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUMKNAVTFCDUIE-VHXPQNKSSA-N
24182	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Wurz GT (2005)	16153821	181910	4734	Ospemifene	2-(P-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol|Deamino-hydroxytoremifene|2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol|Osphena|FC-1271a|FC-1271	osphena	DRUGBANK	DB04938	C24H23ClO2	small molecule	G03XC05	128607-22-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUMKNAVTFCDUIE-VHXPQNKSSA-N
24183	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Komi J (2004)	15255284	181854	4734	Ospemifene	2-(P-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol|Deamino-hydroxytoremifene|2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol|Osphena|FC-1271a|FC-1271	osphena	DRUGBANK	DB04938	C24H23ClO2	small molecule	G03XC05	128607-22-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUMKNAVTFCDUIE-VHXPQNKSSA-N
24184	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	unknown	target	Kuznetsov G (2004)	15313917	181859	4735	E7389	-	-	DRUGBANK	DB04940	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24243	116934	23352	RP5-1126H10.1	UBR4	RBAF600|ZUBR1|p600	9606	Homo sapiens	unknown	target	Huh KW (2005)	16061792	145574	4753	HspE7	HPV E7 Peptide Epitope Vaccine|HPV 16 E7/HSP65 Vaccine	-	DRUGBANK	DB04959	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24257	111831	5894	-	RAF1	CMD1NN|CRAF|NS5|Raf-1|c-Raf	9606	Homo sapiens	unknown	target	Gokhale PC (2002)	12429653	181807	4765	LErafAON	-	-	DRUGBANK	DB04973	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24279	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Farhan H (2006)	16963623	181966	4779	IGN311	-	-	DRUGBANK	DB04988	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24303	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	antagonist	target	Eby G (2005)	16122880	181906	5038	Gallium nitrate	Gallium nitrate (anhydrous)|Nitric acid, gallium salt, anhydrate	ganite	DRUGBANK	DB05260	GaN3O9	small molecule	-	13494-90-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CHPZKNULDCNCBW-UHFFFAOYSA-N
24340	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	unknown	target	Khan N (2008)	17868033	182049	5277	MGCD-0103	MGCD0103	-	DRUGBANK	DB05651	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24341	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	unknown	target	Beckers T (2007)	17455259	182004	5277	MGCD-0103	MGCD0103	-	DRUGBANK	DB05651	-	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24359	109790	3576	-	CXCL8	GCP-1|GCP1|IL8|LECT|LUCT|LYNAP|MDNCF|MONAP|NAF|NAP-1|NAP1	9606	Homo sapiens	antagonist	target	Spoettl T (2007)	16715250	181946	5414	Rivanicline	(3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine|(E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine|(E)-metanicotine|N-methyl-4-(3-pyridinyl)-(3E)-3-buten-1-amine|trans-metanicotine	-	DRUGBANK	DB05855	C10H14N2	small molecule	-	15585-43-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JUOSGGQXEBBCJB-GORDUTHDSA-N
24402	107569	1147	-	CHUK	IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16	9606	Homo sapiens	inhibitor	target	Oka S (2000)	10788610	181749	5519	Acetylcysteine	(R)-Mercapturic acid|N-acetylcysteine|N-Acetyl-L-(+)-cysteine|(2R)-2-acetylamino-3-Sulfanylpropanoic acid|Acetilcisteina|Mercapturic acid|Acetylcysteine|Acetylcysteinum|L-Acetylcysteine|(R)-2-acetylamino-3-Mercaptopropanoic acid|N-ACETYL-L-cysteine|L-alpha-acetamido-beta-Mercaptopropionic acid	parvolex|parvolex liq iv 200mg	DRUGBANK	DB06151	C5H9NO3S	small molecule	V03AB23|S01XA08|R05CB01	616-91-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWKSKIMOESPYIA-BYPYZUCNSA-N
24404	109767	3551	-	IKBKB	IKK-beta|IKK2|IKKB|IMD15|NFKBIKB	9606	Homo sapiens	inhibitor	target	Oka S (2000)	10788610	181749	5519	Acetylcysteine	(R)-Mercapturic acid|N-acetylcysteine|N-Acetyl-L-(+)-cysteine|(2R)-2-acetylamino-3-Sulfanylpropanoic acid|Acetilcisteina|Mercapturic acid|Acetylcysteine|Acetylcysteinum|L-Acetylcysteine|(R)-2-acetylamino-3-Mercaptopropanoic acid|N-ACETYL-L-cysteine|L-alpha-acetamido-beta-Mercaptopropionic acid	parvolex|parvolex liq iv 200mg	DRUGBANK	DB06151	C5H9NO3S	small molecule	V03AB23|S01XA08|R05CB01	616-91-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWKSKIMOESPYIA-BYPYZUCNSA-N
24405	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	antagonist	target	Chen X (2002)	11752352	171740	5520	Rimonabant	-	-	DRUGBANK	DB06155	C22H21Cl3N4O	small molecule	A08AX01	168273-06-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZCPYUJPEARBJL-UHFFFAOYSA-N
24406	107668	1268	RP1-23D17.1	CNR1	CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR	9606	Homo sapiens	antagonist	target	Shire D (1996)	8636122	181704	5520	Rimonabant	-	-	DRUGBANK	DB06155	C22H21Cl3N4O	small molecule	A08AX01	168273-06-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JZCPYUJPEARBJL-UHFFFAOYSA-N
24407	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Church LD (2009)	19169963	182096	5521	Canakinumab	ACZ-885|ACZ885	ilaris	DRUGBANK	DB06168	C6452H9958N1722O2010S42	biologic	L04AC08	914613-48-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24548	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24549	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Radulovic S (2007)	17935273	182057	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24550	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor	target	Patard JJ (2008)	18265991	182064	5545	Temsirolimus	42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin|Torisel	gd-temsirolimus|torisel	DRUGBANK	DB06287	C56H87NO16	small molecule	L01XE09	162635-04-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CBPNZQVSJQDFBE-FUXHJELOSA-N
24567	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Tran TH (2013)	23553601	182241	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24568	109769	3553	-	IL1B	IL-1|IL1-BETA|IL1F2	9606	Homo sapiens	binder	target	Cronstein BN (2013)	23319019	182226	5551	Rilonacept	Arcalyst|interleukin-1 (IL-1) trap	arcalyst	DRUGBANK	DB06372	C9030H13932N2400O2670S74	biologic	L04AC04	501081-76-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24573	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	inhibitor	target	Deeks ED (2012)	23072642	182214	5557	Pazopanib	GW 78603|GW786034|Pazopanibum	votrient	DRUGBANK	DB06589	C21H23N7O2S	small molecule	L01XE11	444731-52-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CUIHSIWYWATEQL-UHFFFAOYSA-N
24588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24590	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24591	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24824	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Norrby K (2010)	21091776	182178	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24825	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Marchetti M (2007)	17692905	182038	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24826	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	inhibitor	target	Takahashi H (2005)	16041398	181901	5634	Dalteparin	Daltepariininatrium|Dalteparinum Natricum|Dalteparinnatrium|Dalteparin sodn sl|Dalteparina sdica|Dalteparino natrio druska|Dalteparin Sodyum|Heparin Fragment KABI 2165|Dalteparyna sodowa|Daltparine sodique|Dalteparin sodium|Dalteparin-ntrium|Tedelparin	fragmin inj.-liq 2500 iu(anti-	DRUGBANK	DB06779	-	small molecule	B01AB04	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
24870	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5665	4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE	-	-	DRUGBANK	DB06844	C21H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBXKBJLIESPLIK-UHFFFAOYSA-N
24871	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5665	4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE	-	-	DRUGBANK	DB06844	C21H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBXKBJLIESPLIK-UHFFFAOYSA-N
24880	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5673	4-[(3S)-1-AZABICYCLO[2.2.2]OCT-3-YLAMINO]-3-(1H-BENZIMIDAZOL-2-YL)-6-CHLOROQUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB06852	C23H22ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOVBBVMDHIRCTG-LJQANCHMSA-N
24892	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5683	2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID	-	-	DRUGBANK	DB06862	C9H11NO5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UCQUNSCHVXCSCJ-UHFFFAOYSA-N
24896	111317	5300	-	PIN1	DOD|UBL5	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5687	3,6,9,12,15,18-HEXAOXAICOSANE	-	-	DRUGBANK	DB06867	C14H30O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IXFAFGFZFQHRLB-UHFFFAOYSA-N
24901	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5691	17-METHYL-17-ALPHA-DIHYDROEQUILENIN	-	-	DRUGBANK	DB06871	C19H22O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQMQOMRDADWGJJ-GBESFXJTSA-N
24906	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5696	N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE	-	-	DRUGBANK	DB06876	C24H24N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJWJKKXGAPWLGT-UHFFFAOYSA-N
24907	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5697	N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB06877	C16H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OPBUUQBZKJSWTN-UHFFFAOYSA-N
24911	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5702	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	-	-	DRUGBANK	DB06882	C24H25N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HJWMLCDGRWWLAQ-UHFFFAOYSA-N
24912	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5702	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	-	-	DRUGBANK	DB06882	C24H25N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HJWMLCDGRWWLAQ-UHFFFAOYSA-N
24913	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5703	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea	-	-	DRUGBANK	DB06883	C20H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DHNYNLNKNQJSHF-UHFFFAOYSA-N
24917	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5708	(13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25),18,20-HEPTAENE-23,26-DIONE	-	-	DRUGBANK	DB06888	C22H21N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBLPHMRCKHFBJB-OLZOCXBDSA-N
24919	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5712	(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide	-	-	DRUGBANK	DB06892	C15H12F3IN2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDLJJGJCIWWATJ-OOHURIHSSA-N
24922	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5716	3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol	-	-	DRUGBANK	DB06897	C23H22ClN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MMGKIHLBFPJYJL-HNNXBMFYSA-N
24924	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5717	4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol	-	-	DRUGBANK	DB06898	C13H12N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UGJXOCBVCWTJFP-UHFFFAOYSA-N
24930	111507	5515	-	PPP2CA	PP2Ac|PP2CA|PP2Calpha|RP-C	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5724	(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid	-	-	DRUGBANK	DB06905	C20H29NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HJVCHYDYCYBBQX-HLTLHRPFSA-N
24950	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5746	[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE	-	-	DRUGBANK	DB06927	C16H11NO3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKJVCUXZMYKTLT-UHFFFAOYSA-N
24963	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5759	N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide	-	-	DRUGBANK	DB06940	C19H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZZTMFGIGOADCFX-UHFFFAOYSA-N
24967	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5763	N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide	-	-	DRUGBANK	DB06944	C18H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIGZCVNCFXYBEG-UHFFFAOYSA-N
24968	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5763	N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide	-	-	DRUGBANK	DB06944	C18H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIGZCVNCFXYBEG-UHFFFAOYSA-N
24971	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5767	2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE	-	-	DRUGBANK	DB06948	C18H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XWWRLKIBRPJQJX-UHFFFAOYSA-N
24972	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5767	2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE	-	-	DRUGBANK	DB06948	C18H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XWWRLKIBRPJQJX-UHFFFAOYSA-N
24980	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5778	(1S)-2-(1H-INDOL-3-YL)-1-{[(5-ISOQUINOLIN-6-YLPYRIDIN-3-YL)OXY]METHYL}ETHYLAMINE	-	-	DRUGBANK	DB06959	C25H22N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BUCZDJYEOAQTHL-VXKWHMMOSA-N
24984	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5782	3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide	-	-	DRUGBANK	DB06963	C24H25N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZFGCLYUGFRNYFE-INIZCTEOSA-N
24991	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5794	1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-(5-PYRROLIDIN-2-YL-1H-PYRAZOL-3-YL)-UREA	-	-	DRUGBANK	DB06976	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IWOOJEZSDPRYAZ-WFASDCNBSA-N
24992	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5795	(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE	-	-	DRUGBANK	DB06977	C23H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAASENZOSQYNPX-WMZHIEFXSA-N
24997	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5801	(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol	-	-	DRUGBANK	DB06983	C19H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RBLKWWBHDUBPFN-UHFFFAOYSA-N
25004	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5809	N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide	-	-	DRUGBANK	DB06991	C17H22N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYOUIHFZUAKCEF-LLVKDONJSA-N
25024	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5828	N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07010	C21H17ClN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PDJZASCRQRBYQS-UHFFFAOYSA-N
25027	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5831	TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE	-	-	DRUGBANK	DB07013	C22H31N3O6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RXFCFGLSOUOCEA-UHFFFAOYSA-N
25028	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5832	2-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazole	-	-	DRUGBANK	DB07014	C17H13FN2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUTZKAQTSPMEBI-UHFFFAOYSA-N
25033	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5838	N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide	-	-	DRUGBANK	DB07020	C20H14N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LMDMJDCLPIVGQD-UHFFFAOYSA-N
25037	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5842	2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE	-	-	DRUGBANK	DB07024	C19H17NO7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEXBEGBNDJVZPK-UHFFFAOYSA-N
25038	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5843	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB07025	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBIHHEGEALBUMT-UHFFFAOYSA-N
25047	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5852	2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID	-	-	DRUGBANK	DB07034	C17H13NO7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOKATEXROYSXDW-UHFFFAOYSA-N
25049	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5855	(2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07037	C12H14N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBZPCTWLFNYBND-QMMMGPOBSA-N
25050	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5856	2-(cyclohexylamino)benzoic acid	-	-	DRUGBANK	DB07038	C13H17NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JSXMFCCPQQJLCR-UHFFFAOYSA-N
25054	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5864	2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide	-	-	DRUGBANK	DB07046	C16H14ClF2IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FCADPEDUULETPK-SECBINFHSA-N
25060	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5872	(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL	-	-	DRUGBANK	DB07054	C22H23F4N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSCWQKTUILTARV-MRXNPFEDSA-N
25063	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5876	5-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2(3H)-thione	-	-	DRUGBANK	DB07058	C16H12N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QBVJMUOTMRYUKR-UHFFFAOYSA-N
25069	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5883	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07065	C19H12Cl2N6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHPKUZJCNHGFQA-UHFFFAOYSA-N
25079	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5893	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)-1H-INDAZOLE-6-CARBONITRILE	-	-	DRUGBANK	DB07075	C23H24N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WBKUBPBCFYCSRT-UHFFFAOYSA-N
25082	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5896	(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB07078	C20H16N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYSXURJZVXBSRV-WJDWOHSUSA-N
25095	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5904	4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	-	-	DRUGBANK	DB07086	C16H20O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XXIFNRNIQJKFLP-XHSDSOJGSA-N
25097	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5905	4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	-	-	DRUGBANK	DB07087	C17H24O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YMSZEVAWRFDVQX-GHVWTTSJSA-N
25111	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5919	N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide	-	-	DRUGBANK	DB07101	C16H14F3IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUDAHWBOROXANE-SECBINFHSA-N
25116	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5925	(1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE	-	-	DRUGBANK	DB07107	C23H22N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SGHXFHRRWFLILP-XJDXJNMNSA-N
25121	120060	54583	PNAS-118	EGLN1	C1orf12|ECYT3|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5930	N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE	-	-	DRUGBANK	DB07112	C12H9IN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FUMNLXHPILGSLC-UHFFFAOYSA-N
25126	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5935	5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE	-	-	DRUGBANK	DB07117	C24H22N6O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FMKQJGOROFNCGM-UHFFFAOYSA-N
25132	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5942	(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	-	-	DRUGBANK	DB07124	C22H20N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCIACUJJBPSOHE-KRWDZBQOSA-N
25134	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5944	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	-	-	DRUGBANK	DB07126	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWXORKPNCHJYOF-UHFFFAOYSA-N
25135	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5944	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	-	-	DRUGBANK	DB07126	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWXORKPNCHJYOF-UHFFFAOYSA-N
25147	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5955	(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE	-	-	DRUGBANK	DB07137	C18H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPAWNIKVRIVDBT-PORMKJMCSA-N
25148	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5955	(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE	-	-	DRUGBANK	DB07137	C18H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPAWNIKVRIVDBT-PORMKJMCSA-N
25149	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5956	5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one	-	-	DRUGBANK	DB07138	C19H9Cl2F2N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEPKQEUBKLEPRA-UHFFFAOYSA-N
25160	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5967	(7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one	-	-	DRUGBANK	DB07149	C13H14FN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LCBAQTCTQXHTJG-ZETCQYMHSA-N
25164	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5970	N-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide	-	-	DRUGBANK	DB07152	C19H15FN6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TYPILNNEZPSNTI-UHFFFAOYSA-N
25168	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5976	5-ETHYL-3-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]QUINOLIN-4-ONE	-	-	DRUGBANK	DB07158	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASEHARDUZDZEKS-UHFFFAOYSA-N
25171	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5979	5-phenyl-1H-indazol-3-amine	-	-	DRUGBANK	DB07161	C13H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCUSNQPYUNLATP-UHFFFAOYSA-N
25172	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5980	4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide	-	-	DRUGBANK	DB07162	C17H20N4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KFJCXIOVAGJCKB-UHFFFAOYSA-N
25173	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5981	5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE	-	-	DRUGBANK	DB07163	C17H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CQCXWWWNUFQYJS-UHFFFAOYSA-N
25174	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5982	N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine	-	-	DRUGBANK	DB07164	C13H12N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAGHIASAHLPQMS-UHFFFAOYSA-N
25175	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5982	N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine	-	-	DRUGBANK	DB07164	C13H12N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAGHIASAHLPQMS-UHFFFAOYSA-N
25186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5996	3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide	-	-	DRUGBANK	DB07179	C19H16BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DXUJQXZHHGJMFM-UHFFFAOYSA-N
25191	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6003	4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE	-	-	DRUGBANK	DB07186	C23H24N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TYYNSDQVFIOSFH-UHFFFAOYSA-N
25192	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6003	4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE	-	-	DRUGBANK	DB07186	C23H24N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TYYNSDQVFIOSFH-UHFFFAOYSA-N
25199	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6012	4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	-	-	DRUGBANK	DB07195	C18H24O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DTZWKYVREFMAJA-QXWBOSQLSA-N
25205	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6020	6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE	-	-	DRUGBANK	DB07203	C18H20ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUEGMEMDEAOAEG-UHFFFAOYSA-N
25206	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6020	6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE	-	-	DRUGBANK	DB07203	C18H20ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUEGMEMDEAOAEG-UHFFFAOYSA-N
25207	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6021	(1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE	-	-	DRUGBANK	DB07204	C24H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQIXTEDFNFZMCM-SFHVURJKSA-N
25215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6027	3-bromo-5-phenyl-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07210	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JECHSYMSTXETFI-UHFFFAOYSA-N
25219	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6030	(5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL	-	-	DRUGBANK	DB07213	C24H25N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FNWHPLLNMLOZTL-UHFFFAOYSA-N
25225	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6034	6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE	-	-	DRUGBANK	DB07218	C12H10ClN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYKGPCNWPACUQV-UHFFFAOYSA-N
25228	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6036	N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE	-	-	DRUGBANK	DB07220	C23H27N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXYIRNXOAJYLCU-UHFFFAOYSA-N
25237	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6044	1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA	-	-	DRUGBANK	DB07228	C17H22ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIAYFZLMPSVQDV-NSHDSACASA-N
25246	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6051	N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07235	C19H19Cl2N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHOVRZGUSBMKKU-ZDUSSCGKSA-N
25253	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6059	(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE	-	-	DRUGBANK	DB07243	C16H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQGFCATXRXQKNB-GDNZZTSVSA-N
25257	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6062	(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE	-	-	DRUGBANK	DB07246	C16H15F3N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MKRPIBSCGZAUCH-OAHLLOKOSA-N
25260	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6064	7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE	-	-	DRUGBANK	DB07248	C20H19N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YENZSPIOXMNEFF-UHFFFAOYSA-N
25276	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6080	(S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07264	C22H17Cl2FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YMUYGRBBEDYUOP-HXUWFJFHSA-N
25278	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6082	8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one	-	-	DRUGBANK	DB07266	C21H24N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AOMMPEGZDRAGRC-UHFFFAOYSA-N
25279	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6083	2-(6-methylpyridin-2-yl)-N-pyridin-4-ylquinazolin-4-amine	-	-	DRUGBANK	DB07267	C19H15N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JONFDFIXMPXTRH-UHFFFAOYSA-N
25280	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6084	2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE	-	-	DRUGBANK	DB07268	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QHPKKGUGRGRSGA-UHFFFAOYSA-N
25284	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6088	N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE	-	-	DRUGBANK	DB07272	C18H19BrN4O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GKODDLYLEKSDJL-UHFFFAOYSA-N
25287	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6092	5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE	-	-	DRUGBANK	DB07276	C18H19N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VEGKZYFYGCWXMN-UHFFFAOYSA-N
25297	110461	4318	-	MMP9	CLG4B|GELB|MANDP2|MMP-9	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6101	(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID	-	-	DRUGBANK	DB07285	C11H12F2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OBQLOVWIRUXBAW-SECBINFHSA-N
25314	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6123	N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide	-	-	DRUGBANK	DB07307	C26H23N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GQXMJOSCBRZMKE-UHFFFAOYSA-N
25318	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6127	18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE	-	-	DRUGBANK	DB07311	C16H17ClN4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRSWWYITYIOHOP-UHFFFAOYSA-N
25321	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6130	1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA	-	-	DRUGBANK	DB07314	C14H12ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	URQYPXQXSVUVRG-UHFFFAOYSA-N
25327	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6136	4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID	-	-	DRUGBANK	DB07320	C25H27N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEDLHZCDTXWLOC-SGNKCFNYSA-N
25339	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6151	3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL	-	-	DRUGBANK	DB07335	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWYBBCLGEHZSCP-UHFFFAOYSA-N
25341	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6152	4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL	-	-	DRUGBANK	DB07336	C21H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GYPHGCGOSZJXOT-UHFFFAOYSA-N
25367	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6176	1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea	-	-	DRUGBANK	DB07360	C19H15F3N6OS2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJHXPDTVQKWKHA-UHFFFAOYSA-N
25368	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6177	1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea	-	-	DRUGBANK	DB07361	C18H15ClN6OS2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FAYAUAZLLLJJGH-UHFFFAOYSA-N
25369	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6178	1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea	-	-	DRUGBANK	DB07362	C19H17F3N8OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UOLCZAFAGDOUFX-UHFFFAOYSA-N
25397	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6195	(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol	(2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol|Aminopurvalanol	-	DRUGBANK	DB07379	C19H26ClN7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAMROQQYRRQPDL-OAHLLOKOSA-N
25428	111189	5163	-	PDK1	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6217	4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE	-	-	DRUGBANK	DB07403	C19H18ClF3N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DTDZLJHKVNTQGZ-GOSISDBHSA-N
25453	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6244	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	-	-	DRUGBANK	DB07431	C13H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXYKBKYDFZQOCB-SSDOTTSWSA-N
25474	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6269	3-(1H-INDOL-3-YL)-4-{1-[2-(1-METHYLPYRROLIDIN-2-YL)ETHYL]-1H-INDOL-3-YL}-1H-PYRROLE-2,5-DIONE	-	-	DRUGBANK	DB07458	C27H26N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBFDERUQORUFIN-KRWDZBQOSA-N
25475	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6270	4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE	-	-	DRUGBANK	DB07459	C19H16N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HVLSCZSVTCNAQX-UHFFFAOYSA-N
25476	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6271	2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE	-	-	DRUGBANK	DB07460	C23H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UYJNQQDJUOUFQJ-UHFFFAOYSA-N
25484	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6282	5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE	-	-	DRUGBANK	DB07471	C22H20ClN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHCHLTQBLNUYRT-GFCCVEGCSA-N
25485	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6282	5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE	-	-	DRUGBANK	DB07471	C22H20ClN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHCHLTQBLNUYRT-GFCCVEGCSA-N
25516	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6304	(2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATE	-	-	DRUGBANK	DB07493	C16H9BrN2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IEQQJQHHJMQETK-YPKPFQOOSA-N
25523	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6312	(2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07501	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-KRWDZBQOSA-N
25526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6315	(2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07504	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-QGZVFWFLSA-N
25543	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6339	2-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONE	-	-	DRUGBANK	DB07529	C9H7N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LHGOQMPIWSCKBA-FNORWQNLSA-N
25546	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6341	4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07531	C14H10N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNPRTUHVCHGFHJ-GHXNOFRVSA-N
25547	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6343	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07533	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJJJERLTHDXEPT-JYRVWZFOSA-N
25548	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6343	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07533	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJJJERLTHDXEPT-JYRVWZFOSA-N
25549	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6344	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07534	C14H11N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKUMVXIXUVYKDQ-GHXNOFRVSA-N
25550	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6344	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07534	C14H11N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKUMVXIXUVYKDQ-GHXNOFRVSA-N
25553	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6348	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07538	C15H10F3N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGVVHQNJKUNSFQ-WDZFZDKYSA-N
25554	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6348	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07538	C15H10F3N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGVVHQNJKUNSFQ-WDZFZDKYSA-N
25555	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6349	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID	-	-	DRUGBANK	DB07539	C15H10N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLRKRQCTYQGDKJ-GHXNOFRVSA-N
25556	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6349	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID	-	-	DRUGBANK	DB07539	C15H10N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLRKRQCTYQGDKJ-GHXNOFRVSA-N
25557	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6350	4-{5-[(1Z)-1-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ETHYL]-2-FURYL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07540	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AKFVRSQELXTCFW-JYRVWZFOSA-N
25562	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6355	N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE	-	-	DRUGBANK	DB07545	C21H18F3N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RDTDWGQDFJPTPD-UHFFFAOYSA-N
25569	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6365	N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE	-	-	DRUGBANK	DB07556	C18H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSIZUMJRKYHEBR-QGZVFWFLSA-N
25577	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6371	N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE	-	-	DRUGBANK	DB07562	C17H19N5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FGGSNQOBRJVAKL-UHFFFAOYSA-N
25578	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6371	N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE	-	-	DRUGBANK	DB07562	C17H19N5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FGGSNQOBRJVAKL-UHFFFAOYSA-N
25580	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6375	(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL	-	-	DRUGBANK	DB07567	C28H31NO4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XPVKGTWRXBSJKO-LHXLBICKSA-N
25591	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6390	(4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE	-	-	DRUGBANK	DB07583	C21H22ClN3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLNNFNGBXLTQOB-RBUKOAKNSA-N
25593	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6391	N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	-	-	DRUGBANK	DB07584	C15H13N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OKGCSZUKOGMZAL-UHFFFAOYSA-N
25594	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6391	N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	-	-	DRUGBANK	DB07584	C15H13N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OKGCSZUKOGMZAL-UHFFFAOYSA-N
25595	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6392	5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine	-	-	DRUGBANK	DB07585	C12H11ClN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFFJXGRXFASBDL-UHFFFAOYSA-N
25596	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6392	5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine	-	-	DRUGBANK	DB07585	C12H11ClN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YFFJXGRXFASBDL-UHFFFAOYSA-N
25605	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6402	(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE	-	-	DRUGBANK	DB07595	C18H15BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WSIQKQLAGWVKSL-UHFFFAOYSA-O
25610	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6408	S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE	-	-	DRUGBANK	DB07602	C20H21N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NLVZTRZPMRTVRC-INIZCTEOSA-N
25613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6412	6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE	-	-	DRUGBANK	DB07606	C20H15Cl3N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OPRAIFVPXXVXDL-UHFFFAOYSA-N
25614	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6413	4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB07607	C21H16IN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RXDZANYWRNIAOR-HHHXNRCGSA-N
25615	108192	1859	-	DYRK1A	DYRK|DYRK1|HP86|MNB|MNBH|MRD7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6414	N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide	-	-	DRUGBANK	DB07608	C24H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JDGOPNUGILVNJZ-IBGZPJMESA-N
25617	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6418	6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE	-	-	DRUGBANK	DB07612	C19H19F3N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XQKJVNGGVLHNLA-UHFFFAOYSA-N
25623	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6424	2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE	-	-	DRUGBANK	DB07618	C24H31N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AITZHKQVQNLKHI-UHFFFAOYSA-N
25626	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6428	1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA	-	-	DRUGBANK	DB07622	C21H23N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKQVGZXTNLQSV-UHFFFAOYSA-N
25644	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6444	(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	-	-	DRUGBANK	DB07638	C18H16F2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QJSMFUTULGSHNQ-ZOBUZTSGSA-N
25646	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6447	DECYL(DIMETHYL)PHOSPHINE OXIDE	-	-	DRUGBANK	DB07641	C12H27OP	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GSVLCKASFMVUSW-UHFFFAOYSA-N
25653	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6453	(2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07647	C21H20N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VBASHTSSQNDDAS-CQSZACIVSA-N
25654	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6454	(2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL	-	-	DRUGBANK	DB07648	C21H20N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWEONIHFGKSPLC-MRXNPFEDSA-N
25657	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6459	N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE	-	-	DRUGBANK	DB07653	C20H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXTCEUDVOCLEJG-UHFFFAOYSA-N
25658	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6460	(5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC	-	-	DRUGBANK	DB07654	C21H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDJWWYRYKMXMKA-UHFFFAOYSA-N
25659	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6461	3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE	-	-	DRUGBANK	DB07655	C20H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MPJYGQHMIFDQIN-UHFFFAOYSA-N
25665	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6468	N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE	-	-	DRUGBANK	DB07662	C17H13BrN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HTUBKQUPEREOGA-UHFFFAOYSA-N
25666	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6468	N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE	-	-	DRUGBANK	DB07662	C17H13BrN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HTUBKQUPEREOGA-UHFFFAOYSA-N
25683	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6482	3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one	-	-	DRUGBANK	DB07676	C20H19N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CKLAPOFDFZKCPB-LBPRGKRZSA-N
25687	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6484	(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL	-	-	DRUGBANK	DB07678	C22H30O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ANAMDWGJXBYJEB-SHKDNAECSA-N
25692	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6490	4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07685	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMAZGYDYIYLSLJ-UHFFFAOYSA-N
25693	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6491	4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07686	C17H21N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPOGRVWIIVMWRI-UHFFFAOYSA-N
25694	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6492	4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07687	C17H22N8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVRKQJAEQWVSCM-HAQNSBGRSA-N
25695	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6493	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07688	C17H20N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPJIMTALCNCQLV-UHFFFAOYSA-N
25696	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6493	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07688	C17H20N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPJIMTALCNCQLV-UHFFFAOYSA-N
25703	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6501	methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate	-	-	DRUGBANK	DB07696	C11H19NO5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKEQESWFLCEUCV-QMMMGPOBSA-N
25712	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6511	(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL	-	-	DRUGBANK	DB07707	C20H28O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LEOPSILMAOYZBO-IUTAEKPZSA-N
25714	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6512	3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL	-	-	DRUGBANK	DB07708	C13H9ClN2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZNHQDSBJVFFIAK-UHFFFAOYSA-N
25718	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6515	3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL	-	-	DRUGBANK	DB07712	C15H14N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XBMVVMYGKMGLJX-UHFFFAOYSA-N
25721	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6518	Emodin	3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE|Emodin|Emodol|Frangula Emodin|Schuttgelb|1,3,8-Trihydroxy-6-Methylanthracene-9,10-Dione|Rheum Emodin|Archin	-	DRUGBANK	DB07715	C15H10O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHMXXJGYXNZAPX-UHFFFAOYSA-N
25736	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6532	4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL	-	-	DRUGBANK	DB07731	C9H10N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYZRKFOEZQBUEA-OUKQBFOZSA-N
25744	109400	3157	-	HMGCS1	HMGCS	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6541	(3R,5S,7R,12S,13R)-13-FORMYL-12,14-DIHYDROXY-3,5,7-TRIMETHYLTETRADECANOIC ACID	-	-	DRUGBANK	DB07740	C18H34O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IXYKBBOQNSGWJZ-JJTUDDRGSA-N
25751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6551	(2R)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07750	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-MRXNPFEDSA-N
25752	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6552	(2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07751	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-HNNXBMFYSA-N
25763	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6556	(2S)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07755	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-INIZCTEOSA-N
25769	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6562	(2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07761	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-OAHLLOKOSA-N
25816	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6587	(3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE	-	-	DRUGBANK	DB07788	C19H22O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NEQZWEXWOFPKOT-RCPUWQGCSA-N
25817	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6588	1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea	-	-	DRUGBANK	DB07789	C18H17F3N10O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KNTGXMNWVXZIMW-UHFFFAOYSA-N
25818	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6589	N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07790	C20H26N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LDXLQEXLXZCYSR-UHFFFAOYSA-N
25819	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6590	4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07791	C18H20N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MZWCVBFANHIPTJ-UHFFFAOYSA-N
25822	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6593	5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE	-	-	DRUGBANK	DB07794	C18H13N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XVECMUKVOMUNLE-UHFFFAOYSA-N
25823	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6594	3,7,3',4'-TETRAHYDROXYFLAVONE	-	-	DRUGBANK	DB07795	C15H10O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XHEFDIBZLJXQHF-UHFFFAOYSA-N
25827	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6599	N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide	-	-	DRUGBANK	DB07801	C22H29N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WOYITRCGMUXUDE-UHFFFAOYSA-N
25828	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6600	3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE	-	-	DRUGBANK	DB07802	C10H6Br2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSOLROYRAHCJNK-UHFFFAOYSA-N
25833	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6609	N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide	-	-	DRUGBANK	DB07811	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBVTVSINEVHYSY-UHFFFAOYSA-N
25834	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6610	N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide	-	-	DRUGBANK	DB07812	C20H18N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWYNGDRSMHRPSY-MRXNPFEDSA-N
25846	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6625	4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID	-	-	DRUGBANK	DB07827	C26H20N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FLTYDFYSVZBKOB-UHFFFAOYSA-N
25847	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6626	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE	-	-	DRUGBANK	DB07829	C14H10FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BILJSHVAAVZERY-UHFFFAOYSA-N
25850	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6629	4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde	-	-	DRUGBANK	DB07832	C20H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKQPTVJDZIILPG-UHFFFAOYSA-N
25851	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6630	N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide	-	-	DRUGBANK	DB07833	C24H18N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PMMLSQFPBFKLHH-UHFFFAOYSA-N
25852	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6631	N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	-	-	DRUGBANK	DB07834	C21H21N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOHZGCHKLPIBBX-UHFFFAOYSA-N
25853	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6632	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide	-	-	DRUGBANK	DB07835	C22H24N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPSUAHGQHFKGG-UHFFFAOYSA-N
25869	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6642	2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide	-	-	DRUGBANK	DB07845	C22H21FN6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VGYXXQRDIVRILX-UHFFFAOYSA-N
25876	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6649	1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID	-	-	DRUGBANK	DB07852	C10H7Cl2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CZTNDZALWLHXBA-UHFFFAOYSA-N
25877	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6649	1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID	-	-	DRUGBANK	DB07852	C10H7Cl2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CZTNDZALWLHXBA-UHFFFAOYSA-N
25881	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6651	N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE	-	-	DRUGBANK	DB07854	C13H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VRGSDHJXBVCQEL-UHFFFAOYSA-N
25883	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6652	(S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE	-	-	DRUGBANK	DB07855	C18H15N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CWHMAWBXRCDOEB-HNNXBMFYSA-N
25885	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6653	6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE	-	-	DRUGBANK	DB07856	C22H20ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HPWBHQIUIBFTQC-UHFFFAOYSA-N
25887	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6654	(2R)-2-(4-CHLOROPHENYL)-2-[4-(1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	-	-	DRUGBANK	DB07857	C17H16ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HWVGILTYGZFGLR-QGZVFWFLSA-N
25889	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6655	(2S)-2-(4-CHLOROPHENYL)-2-[4-(1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	-	-	DRUGBANK	DB07858	C17H16ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HWVGILTYGZFGLR-KRWDZBQOSA-N
25891	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6656	4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE	-	-	DRUGBANK	DB07859	C20H20ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZMOSYUFVYJEPY-UHFFFAOYSA-N
25892	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6656	4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE	-	-	DRUGBANK	DB07859	C20H20ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZMOSYUFVYJEPY-UHFFFAOYSA-N
25895	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6657	(2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE	-	-	DRUGBANK	DB07860	C14H14ClN	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNKKPFLBOWGVSF-CQSZACIVSA-N
25907	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6673	(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE	-	-	DRUGBANK	DB07876	C16H21N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWDORCFLUJZUQS-ZDUSSCGKSA-N
25919	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6686	1-(DIMETHYLAMINO)-3-(4-{{4-(2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PHENOXY)PROPAN-2-OL	-	-	DRUGBANK	DB07889	C23H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VCPXSBULBDYRLT-SFHVURJKSA-N
25929	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6701	(1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione	-	-	DRUGBANK	DB07905	C19H22O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SSNQAUBBJYCSMY-KNTMUCJRSA-N
25946	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6715	7-METHOXY-1-METHYL-9H-BETA-CARBOLINE	-	-	DRUGBANK	DB07919	C13H12N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BXNJHAXVSOCGBA-UHFFFAOYSA-N
25952	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6722	N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE	-	-	DRUGBANK	DB07926	C19H29N3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QYZPDCGWIJYZMN-ZBFHGGJFSA-N
25960	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6728	dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate	-	-	DRUGBANK	DB07932	C22H18O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CRLQCBACIMUGDZ-BGYRXZFFSA-N
25962	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6729	(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	-	-	DRUGBANK	DB07933	C18H18O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XIESSJVMWNJCGZ-VKJFTORMSA-N
25964	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6732	N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine	-	-	DRUGBANK	DB07936	C24H30FN7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BACSZMCLZIDTIO-IBGZPJMESA-N
25966	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6737	3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide	-	-	DRUGBANK	DB07941	C22H19BrF2N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KCAJXIDMCNPGHZ-UHFFFAOYSA-N
25967	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6738	2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine	-	-	DRUGBANK	DB07942	C14H9F2N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJCHZVXSPFPKMX-UHFFFAOYSA-N
25968	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6739	2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07943	C20H20ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CATQHDWESBRRQA-UHFFFAOYSA-N
25971	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6743	ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE	-	-	DRUGBANK	DB07947	C20H22ClN3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUHWQSZMVMMRLM-UHFFFAOYSA-N
25972	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6743	ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE	-	-	DRUGBANK	DB07947	C20H22ClN3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUHWQSZMVMMRLM-UHFFFAOYSA-N
25991	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6754	3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE	-	-	DRUGBANK	DB07959	C14H10N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTKFRFMSUBOCIQ-UHFFFAOYSA-N
25995	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6761	[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile	-	-	DRUGBANK	DB07966	C22H19N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVMCVWOODOWOLT-UHFFFAOYSA-N
26009	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6777	2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07982	C23H29N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVTKDXZNSUHUMO-UHFFFAOYSA-N
26016	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6786	N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE	-	-	DRUGBANK	DB07991	C26H26N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	APLJSSOXDWUNGV-GOSISDBHSA-N
26019	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6790	N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE	-	-	DRUGBANK	DB07995	C20H20BrN3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKZXNDJNWUTGDK-NSCUHMNNSA-N
26022	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6791	5-(2-methylpiperazine-1-sulfonyl)isoquinoline	1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine|1-(5-Isoquinolinesulfonyl)-2-methylpiperazine	-	DRUGBANK	DB07996	C14H17N3O2S	small molecule	-	84477-87-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDVFVCGFMNCYPV-UHFFFAOYSA-N
26024	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6792	N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE	-	-	DRUGBANK	DB07997	C12H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PJWUXKNZVMEPPH-UHFFFAOYSA-N
26044	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6813	(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	-	-	DRUGBANK	DB08020	C20H22O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RHQLNMNKTIOREN-AOIWGVFYSA-N
26068	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6840	4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol	-	-	DRUGBANK	DB08047	C17H13F3N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZDUDMCQPFKPISO-UHFFFAOYSA-N
26070	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6841	4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL	-	-	DRUGBANK	DB08048	C13H10N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WLDZDEMGKFWJNR-UHFFFAOYSA-N
26073	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6845	1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	-	-	DRUGBANK	DB08052	C17H17N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVRXTLZYXZNATH-UHFFFAOYSA-N
26074	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6846	1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	-	-	DRUGBANK	DB08053	C17H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ITOYZJGFTNTKKR-UHFFFAOYSA-N
26075	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6847	1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	-	-	DRUGBANK	DB08054	C17H16N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GEZALMMCQYDFML-UHFFFAOYSA-N
26081	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6852	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	-	-	DRUGBANK	DB08059	C23H24O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QDLHCMPXEPAAMD-QAIWCSMKSA-N
26083	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6852	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	-	-	DRUGBANK	DB08059	C23H24O8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QDLHCMPXEPAAMD-QAIWCSMKSA-N
26089	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6857	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	-	-	DRUGBANK	DB08064	C20H22ClN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NTMADESEDXKNFZ-UHFFFAOYSA-N
26090	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6858	2-(1H-pyrazol-3-yl)-1H-benzimidazole	-	-	DRUGBANK	DB08065	C10H8N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IYTGPPNUOLLGBE-UHFFFAOYSA-N
26091	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6859	N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE	-	-	DRUGBANK	DB08066	C17H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPKSFXFWECAIBR-UHFFFAOYSA-N
26092	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6859	N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE	-	-	DRUGBANK	DB08066	C17H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPKSFXFWECAIBR-UHFFFAOYSA-N
26093	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6860	4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM	-	-	DRUGBANK	DB08067	C19H24N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LOLPPWBBNUVNQZ-UHFFFAOYSA-O
26094	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6861	N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-	-	-	DRUGBANK	DB08068	C23H25ClFN3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YQJVDUKATDECHF-ICSRJNTNSA-N
26095	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6863	2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	-	-	DRUGBANK	DB08070	C12H15N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ILTOXASLQDKYJW-UHFFFAOYSA-N
26098	109187	2932	-	GSK3B	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6866	(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	-	-	DRUGBANK	DB08073	C24H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWTBGJGMTBHQTM-IBGZPJMESA-N
26099	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6866	(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	-	-	DRUGBANK	DB08073	C24H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWTBGJGMTBHQTM-IBGZPJMESA-N
26119	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6884	3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE	-	-	DRUGBANK	DB08091	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIUFYIOMUILESI-UHFFFAOYSA-N
26120	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6885	3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide	-	-	DRUGBANK	DB08092	C19H18FN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VMLSXFMXUNVCSK-UHFFFAOYSA-N
26121	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6886	3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE	-	-	DRUGBANK	DB08093	C16H14N2O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SZANYTFSQVBOBA-UHFFFAOYSA-N
26122	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6887	(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE	-	-	DRUGBANK	DB08094	C18H21F2N5O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRNJNYBQQYBCLE-UHFFFAOYSA-N
26123	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6888	3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA	-	-	DRUGBANK	DB08095	C23H26ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWYFTKPEHRQCCW-HNNXBMFYSA-N
26124	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6889	8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM	-	-	DRUGBANK	DB08096	C19H15ClF2N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZWKOUFZHPNIQSH-UHFFFAOYSA-N
26125	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6890	2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE	-	-	DRUGBANK	DB08097	C20H16F3N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OGWSGDLIXOEZJG-UHFFFAOYSA-N
26134	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6906	3-pyridin-4-yl-1H-indazole	-	-	DRUGBANK	DB08113	C12H9N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MSRXUUDVRNWSTN-UHFFFAOYSA-N
26136	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6907	5-benzyl-1,3-thiazol-2-amine	-	-	DRUGBANK	DB08114	C10H10N2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJIMLXBJUVLMMN-UHFFFAOYSA-N
26141	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6914	N-METHYL-4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB08122	C16H15N3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKASAFLVQIJQOK-UVTDQMKNSA-N
26142	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6915	N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE	-	-	DRUGBANK	DB08123	C17H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GEWPSTLKJDIUHW-UHFFFAOYSA-N
26143	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6916	3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB08124	C20H15N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FTQYGMLRLRXBPT-IDUWFGFVSA-N
26144	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6917	4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB08125	C18H14N4O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOMPRXSVSIPRDT-PTNGSMBKSA-N
26145	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6918	3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE	-	-	DRUGBANK	DB08126	C16H15N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DMCRNUMVSATRTP-LCYFTJDESA-N
26148	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6922	N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine	-	-	DRUGBANK	DB08130	C16H13F3IN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPDWDLAITHFTTP-UHFFFAOYSA-N
26150	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6924	5-hydroxynaphthalene-1-sulfonamide	-	-	DRUGBANK	DB08132	C10H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFVBVKHGDDDCEA-UHFFFAOYSA-N
26151	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6925	N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide	-	-	DRUGBANK	DB08133	C14H12N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNHPHKFLWAPNOV-UHFFFAOYSA-N
26152	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6926	4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide	-	-	DRUGBANK	DB08134	C10H9ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RSNSGNZRUMHXAY-UHFFFAOYSA-N
26153	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6927	N-phenyl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08135	C10H9N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMZYZYFPPQOFKY-UHFFFAOYSA-N
26154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6928	4-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08136	C12H11FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CWQKPKYIMQTGJK-UHFFFAOYSA-N
26155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6929	(4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08137	C17H13FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZMWYSLJBNJUCRK-UHFFFAOYSA-N
26156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6930	{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08138	C17H11F3N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDRDBXXWQDFXEC-UHFFFAOYSA-N
26157	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6931	5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile	-	-	DRUGBANK	DB08139	C10H10ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFTLYNKTSANXFA-UHFFFAOYSA-N
26158	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6932	5-[(4-AMINOCYCLOHEXYL)AMINO]-7-(PROPAN-2-YLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE	-	-	DRUGBANK	DB08140	C16H23N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOESVLPZMGVWBM-JOCQHMNTSA-N
26159	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6933	4-{[(2,6-difluorophenyl)carbonyl]amino}-N-[(3S)-piperidin-3-yl]-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08141	C16H17F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KOMNQBZWMCFDTQ-VIFPVBQESA-N
26160	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6934	4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08142	C16H17Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVPNQJVDAFNBDN-UHFFFAOYSA-N
26166	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6940	1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine	-	-	DRUGBANK	DB08148	C18H20ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QOZMRRGNAZNWDN-UHFFFAOYSA-N
26168	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6941	1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine	-	-	DRUGBANK	DB08149	C19H22ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KCWPSUKJCKZEAO-UHFFFAOYSA-N
26170	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6942	4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium	-	-	DRUGBANK	DB08150	C18H21ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RZIDZIGAXXNODG-UHFFFAOYSA-O
26182	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6954	5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE	-	-	DRUGBANK	DB08162	C14H17N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NGOGFTYYXHNFQH-UHFFFAOYSA-N
26203	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6970	4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08178	C12H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGEWEQJWGGJUHO-UHFFFAOYSA-N
26204	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6970	4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08178	C12H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGEWEQJWGGJUHO-UHFFFAOYSA-N
26208	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6974	4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08182	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZHMRPXZRUZLCNL-UHFFFAOYSA-N
26209	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6974	4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08182	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZHMRPXZRUZLCNL-UHFFFAOYSA-N
26210	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6975	3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile	-	-	DRUGBANK	DB08183	C16H20N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UJLAWZDWDVHWOW-YPMHNXCESA-N
26212	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6975	3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile	-	-	DRUGBANK	DB08183	C16H20N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UJLAWZDWDVHWOW-YPMHNXCESA-N
26213	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6975	3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile	-	-	DRUGBANK	DB08183	C16H20N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UJLAWZDWDVHWOW-YPMHNXCESA-N
26215	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6978	(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE	-	-	DRUGBANK	DB08186	C13H13NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCYQBFAGILCNRB-BQYQJAHWSA-N
26219	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6983	2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE	-	-	DRUGBANK	DB08192	C16H18N2O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HCUGCUQZFBURHR-LBPRGKRZSA-N
26228	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6999	2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE	-	-	DRUGBANK	DB08208	C17H13F3N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMNKRBRQQAMACZ-UHFFFAOYSA-N
26230	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7004	1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE	-	-	DRUGBANK	DB08213	C20H20N2O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PFAYCUAUBOGVDX-AWEZNQCLSA-N
26234	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7009	HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM	-	-	DRUGBANK	DB08218	C19H15N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLQVWKCQWFFUFJ-FCDQGJHFSA-N
26235	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7009	HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM	-	-	DRUGBANK	DB08218	C19H15N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLQVWKCQWFFUFJ-FCDQGJHFSA-N
26236	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7010	4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE	-	-	DRUGBANK	DB08219	C18H20N6OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPSZSAKYXPWBRR-RELWKKBWSA-N
26237	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7010	4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE	-	-	DRUGBANK	DB08219	C18H20N6OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPSZSAKYXPWBRR-RELWKKBWSA-N
26246	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7019	[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID	-	-	DRUGBANK	DB08229	C20H23N3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JGMMFVVACJREFE-KRWDZBQOSA-N
26254	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7021	MYRISTIC ACID	-	-	DRUGBANK	DB08231	C14H28O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUNFSRHWOTWDNC-UHFFFAOYSA-N
26264	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7021	MYRISTIC ACID	-	-	DRUGBANK	DB08231	C14H28O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUNFSRHWOTWDNC-UHFFFAOYSA-N
26273	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7023	6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE	-	-	DRUGBANK	DB08233	C18H21N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFSDQDHHBKYQOD-UHFFFAOYSA-N
26274	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7023	6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE	-	-	DRUGBANK	DB08233	C18H21N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFSDQDHHBKYQOD-UHFFFAOYSA-N
26294	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7031	4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE	-	-	DRUGBANK	DB08241	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUUOIINPNMNPIU-UHFFFAOYSA-N
26295	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7031	4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE	-	-	DRUGBANK	DB08241	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUUOIINPNMNPIU-UHFFFAOYSA-N
26296	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7032	N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	-	-	DRUGBANK	DB08242	C20H18N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYTBZXSFNNAVKU-UHFFFAOYSA-N
26299	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7036	6-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINE	-	-	DRUGBANK	DB08247	C15H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JABXNQUXGJTKRO-UHFFFAOYSA-N
26300	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7037	3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE	-	-	DRUGBANK	DB08248	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKDUVKJYBJDZQW-UHFFFAOYSA-N
26301	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7037	3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE	-	-	DRUGBANK	DB08248	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKDUVKJYBJDZQW-UHFFFAOYSA-N
26304	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7040	4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID	-	-	DRUGBANK	DB08251	C17H14N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNRAPROKLOUIRA-AWEZNQCLSA-N
26325	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7073	(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	-	-	DRUGBANK	DB08285	C19H26N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQUNOCMDMIQIQK-OAHLLOKOSA-N
26326	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7073	(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	-	-	DRUGBANK	DB08285	C19H26N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQUNOCMDMIQIQK-OAHLLOKOSA-N
26329	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7078	N-(3-AMINOPROPYL)-2-NITROBENZENAMINE	-	-	DRUGBANK	DB08291	C9H13N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GVGDDEYVTBKACE-UHFFFAOYSA-N
26346	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7096	3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL	-	-	DRUGBANK	DB08309	C23H32N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMFGILNPFBVREA-UHFFFAOYSA-N
26347	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7096	3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL	-	-	DRUGBANK	DB08309	C23H32N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMFGILNPFBVREA-UHFFFAOYSA-N
26348	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7098	6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE	-	-	DRUGBANK	DB08312	C11H17N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGWXOLHKVGDQLN-UHFFFAOYSA-N
26356	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7106	DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE	-	-	DRUGBANK	DB08320	C24H24O7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHKDFDHHMHBFLG-COPRSSIGSA-N
26380	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7124	19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one	-	-	DRUGBANK	DB08338	C19H21N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HIJNSOUPEZHEMC-UHFFFAOYSA-N
26382	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7126	N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE	-	-	DRUGBANK	DB08340	C17H14N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LLYYAUZAGCZEKV-UHFFFAOYSA-N
26390	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7130	4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE	-	-	DRUGBANK	DB08345	C17H15N9	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IWUUKHQIKFHWIW-UHFFFAOYSA-N
26396	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7134	N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide	-	-	DRUGBANK	DB08349	C24H21F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMEYCLAVMZKZCS-UHFFFAOYSA-N
26398	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7136	N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide	-	-	DRUGBANK	DB08351	C25H29N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNEXDVSJIUQQRH-UHFFFAOYSA-N
26399	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7137	6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine	-	-	DRUGBANK	DB08352	C19H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FQYJTHIYAQQJAB-UHFFFAOYSA-N
26400	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7138	2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE	-	-	DRUGBANK	DB08353	C19H21N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NCVMTHVSAJMOPI-UHFFFAOYSA-N
26401	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7139	2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE	-	-	DRUGBANK	DB08354	C19H14ClN7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QCVULERVJOYHCP-UHFFFAOYSA-N
26402	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7140	1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid	-	-	DRUGBANK	DB08355	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOBRPBVIEUWYJR-UHFFFAOYSA-N
26403	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7140	1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid	-	-	DRUGBANK	DB08355	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOBRPBVIEUWYJR-UHFFFAOYSA-N
26410	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7145	2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE	-	-	DRUGBANK	DB08360	C18H20N8	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIFHJPUTQBOBGJ-UHFFFAOYSA-N
26412	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7147	N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE	-	-	DRUGBANK	DB08362	C20H16N8O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QVKXQLGRDOMAGC-UHFFFAOYSA-N
26413	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7148	1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine	-	-	DRUGBANK	DB08363	C16H18N2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LBPNOEAFWYTTEB-UHFFFAOYSA-N
26434	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7172	5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE	-	-	DRUGBANK	DB08388	C20H19FN2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XRSYNYGEEYTXJV-UHFFFAOYSA-N
26437	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7176	2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL	-	-	DRUGBANK	DB08392	C22H21N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARBUGBBNEFAECO-UHFFFAOYSA-N
26438	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7177	2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL	-	-	DRUGBANK	DB08393	C20H17N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQHINZSKNAAVOZ-UHFFFAOYSA-N
26440	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7179	2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE	-	-	DRUGBANK	DB08395	C22H18FN3O5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSOXFJURLPCSOO-UHFFFAOYSA-N
26443	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7182	2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE	-	-	DRUGBANK	DB08398	C13H12N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQVKZNNCIHJZLS-UHFFFAOYSA-N
26452	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7187	METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID	-	-	DRUGBANK	DB08403	C18H27N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOPRTFSMCQNUCT-CABCVRRESA-N
26468	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7205	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	-	-	DRUGBANK	DB08423	C21H21FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QKZZJXRGCHXIAI-UHFFFAOYSA-N
26469	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7206	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE	-	-	DRUGBANK	DB08424	C19H18FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IJDQETGUEUJVTB-HNNXBMFYSA-N
26492	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7223	6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE	-	-	DRUGBANK	DB08441	C13H14BrN5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWSQADBSXFTFKL-UHFFFAOYSA-N
26499	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7232	N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine	-	-	DRUGBANK	DB08450	C21H16N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HNHRWNUXTCATSG-UHFFFAOYSA-N
26513	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7243	N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE	-	-	DRUGBANK	DB08462	C17H14N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JGWHILNNHLDARR-UHFFFAOYSA-N
26514	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7244	(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol	-	-	DRUGBANK	DB08463	C24H29N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOCBJBNQIQQQGT-LJQANCHMSA-N
26515	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7244	(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol	-	-	DRUGBANK	DB08463	C24H29N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOCBJBNQIQQQGT-LJQANCHMSA-N
26522	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7254	5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole	-	-	DRUGBANK	DB08473	C12H12Cl2N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XHSQDZXAVJRBMX-DDHJBXDOSA-N
26529	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7263	[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER	-	-	DRUGBANK	DB08482	C19H35N3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XKRONJXEXGFBRZ-ZNMIVQPWSA-N
26536	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7270	CTS-1027	4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL]-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE|193022-04-7|RS-130830|Ro-1130830	-	DRUGBANK	DB08490	C19H20ClNO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ROSNVSQTEGHUKU-UHFFFAOYSA-N
26537	110456	4312	-	MMP1	CLG|CLGN	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7271	N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE	-	-	DRUGBANK	DB08491	C19H21NO6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARIRIZBKMKMEBD-UHFFFAOYSA-N
26541	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7276	(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate	-	-	DRUGBANK	DB08497	C19H14N2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKBDSMREMMRFSI-INIZCTEOSA-N
26542	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7277	(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate	-	-	DRUGBANK	DB08498	C19H13ClN2O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVSAMUIBGQSLDC-INIZCTEOSA-N
26543	107286	836	-	CASP3	CPP32|CPP32B|SCA-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7278	N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide	-	-	DRUGBANK	DB08499	C21H18FN3O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DQXBKUVWJSZHSI-UHFFFAOYSA-N
26552	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7292	[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID	-	-	DRUGBANK	DB08513	C20H19N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAIQRYUOBBCBSE-UHFFFAOYSA-N
26570	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7299	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB08521	C21H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDMGBJANTYXAIV-HHHXNRCGSA-N
26571	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7299	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	-	-	DRUGBANK	DB08521	C21H16FN3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CDMGBJANTYXAIV-HHHXNRCGSA-N
26572	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7300	4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE	-	-	DRUGBANK	DB08522	C18H16FN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ROKOFZNQCIIJMI-UHFFFAOYSA-N
26575	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7305	1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08527	C15H12N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGAKLLFPOGATII-UHFFFAOYSA-N
26576	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7305	1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08527	C15H12N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGAKLLFPOGATII-UHFFFAOYSA-N
26579	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7309	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08531	C18H13Cl2N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CVYWYUAQFJMLEO-UHFFFAOYSA-N
26580	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7310	6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08532	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCNPGRRMPFCHEO-UHFFFAOYSA-N
26581	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7311	3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08533	C13H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LXRVAGIYXNQOKP-UHFFFAOYSA-N
26582	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7312	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08534	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZAIYYXVHGBMLEC-UHFFFAOYSA-N
26583	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7313	3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08535	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMIZFGZXFDGISG-UHFFFAOYSA-N
26584	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7314	3-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine	-	-	DRUGBANK	DB08536	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IBUPHWYGVDAASU-UHFFFAOYSA-N
26585	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7315	3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine	-	-	DRUGBANK	DB08537	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZLKFNBMXXLTLX-UHFFFAOYSA-N
26586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7316	N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08538	C19H17F2N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HQPVGVSQPQVZLD-UHFFFAOYSA-N
26587	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7317	3-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08539	C21H19N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCDIUVLNHCGSMH-UHFFFAOYSA-N
26602	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7339	BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE	-	-	DRUGBANK	DB08561	C21H16N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLBINCOCFGQAJM-UHFFFAOYSA-N
26606	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7341	(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide	-	-	DRUGBANK	DB08564	C20H20BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCIXBBSRVLSRJQ-QPJJXVBHSA-N
26609	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7345	(2S)-1-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-PHENYLPROPAN-2-AMINE	-	-	DRUGBANK	DB08568	C22H22N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BPNUQXPIQBZCMR-IBGZPJMESA-N
26611	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7346	3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE	-	-	DRUGBANK	DB08569	C22H21BrN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VLPMRZSKJUTRBQ-IBGZPJMESA-N
26613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7349	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	-	-	DRUGBANK	DB08572	C18H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBKLJTXDSBEVRV-UHFFFAOYSA-N
26614	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7349	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	-	-	DRUGBANK	DB08572	C18H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBKLJTXDSBEVRV-UHFFFAOYSA-N
26627	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7372	4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	-	-	DRUGBANK	DB08595	C17H22O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BBZPJHFECDCNGT-BPUTZDHNSA-N
26672	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7429	9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE	-	-	DRUGBANK	DB08655	C14H13NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MIGJEXKBUJPKJF-UHFFFAOYSA-N
26675	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7434	1,2,5,8-tetrahydroxyanthracene-9,10-dione	-	-	DRUGBANK	DB08660	C14H8O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VBHKTXLEJZIDJF-UHFFFAOYSA-N
26684	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7447	4-[(5-ISOPROPYL-1,3-THIAZOL-2-YL)AMINO]BENZENESULFONAMIDE	-	-	DRUGBANK	DB08673	C12H15N3O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LPQUJAANWFHCJV-UHFFFAOYSA-N
26690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7451	N-(5-ISOPROPYL-THIAZOL-2-YL)-2-PYRIDIN-3-YL-ACETAMIDE	-	-	DRUGBANK	DB08677	C13H15N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZOOPQQADNJEG-UHFFFAOYSA-N
26692	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7457	REL-(9R,12S)-9,10,11,12-TETRAHYDRO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-1,3(2H)-DIONE	-	-	DRUGBANK	DB08683	C24H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTPNDVKVEAIXTI-IYBDPMFKSA-N
26693	120060	54583	PNAS-118	EGLN1	C1orf12|ECYT3|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7461	N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE	-	-	DRUGBANK	DB08687	C12H9ClN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUQVKRKGTAUJQA-UHFFFAOYSA-N
26694	109338	3091	-	HIF1A	HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7461	N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE	-	-	DRUGBANK	DB08687	C12H9ClN2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUQVKRKGTAUJQA-UHFFFAOYSA-N
26721	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7468	9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol	-	-	DRUGBANK	DB08694	C14H11N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTHKPHCVZVYDFN-UHFFFAOYSA-N
26722	107331	890	-	CCNA2	CCN1|CCNA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7468	9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol	-	-	DRUGBANK	DB08694	C14H11N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTHKPHCVZVYDFN-UHFFFAOYSA-N
26736	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7503	3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	-	-	DRUGBANK	DB08730	C26H25FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPFBZMFUCGHBAP-UHFFFAOYSA-N
26740	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7510	(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL	-	-	DRUGBANK	DB08737	C18H18O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FSYFYSFYUHBIHE-GLJUWKHASA-N
26752	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7524	N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE	-	-	DRUGBANK	DB08751	C12H15N5O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YSVJZZZGPPWEIC-UHFFFAOYSA-N
26755	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7529	(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE	-	-	DRUGBANK	DB08756	C14H21N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IYOZTVGMEWJPKR-IJLUTSLNSA-N
26768	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7541	N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE	-	-	DRUGBANK	DB08768	C10H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYVABZIGRDEKCD-UHFFFAOYSA-N
26774	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7545	RALOXIFENE CORE	-	-	DRUGBANK	DB08773	C14H10O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDGWZLQPNOETLH-UHFFFAOYSA-N
26775	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7546	1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine	-	-	DRUGBANK	DB08774	C17H19N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBRZCAKSBYWZTC-ZDUSSCGKSA-N
26777	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7548	N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE	-	-	DRUGBANK	DB08776	C9H11N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYHOEDBNAJPFKK-UHFFFAOYSA-N
26778	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7549	5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE	-	-	DRUGBANK	DB08777	C10H10N2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMMOEJUJKIXUQZ-UHFFFAOYSA-N
26779	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7550	[4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone	-	-	DRUGBANK	DB08778	C14H17N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KEHNGAHNKVLUSC-UHFFFAOYSA-N
26780	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7551	2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol	-	-	DRUGBANK	DB08779	C9H10N2OS2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QWYGHJVEZLVLSU-UHFFFAOYSA-N
26781	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7552	6-MORPHOLIN-4-YL-9H-PURINE	-	-	DRUGBANK	DB08780	C9H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEOMXKNIFWDDGZ-UHFFFAOYSA-N
26782	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7553	1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE	-	-	DRUGBANK	DB08781	C11H14BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BJUBFXSKTBULRW-ZETCQYMHSA-N
26829	111189	5163	-	PDK1	-	9606	Homo sapiens	inhibitor	target	Stacpoole PW (1989)	2554095	181656	7580	Dichloroacetic Acid	dichloracetic acid|dichloroacetate|DCA	bichloracetic acid 100%	DRUGBANK	DB08809	C2H2Cl2O2	small molecule	-	79-43-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JXTHNDFMNIQAHM-UHFFFAOYSA-N
26844	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	inhibitor	target	Sustar V (2009)	19261492	182099	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26845	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	inhibitor	target	Nagy Z (2009)	19757196	182127	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26846	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	inhibitor	target	Sustar V (2009)	19261492	182099	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26847	108636	2353	-	FOS	AP-1|C-FOS|p55	9606	Homo sapiens	inhibitor	target	Nagy Z (2009)	19757196	182127	7583	Nadroparin	-	fraxiparine forte|fraxiparine	DRUGBANK	DB08813	-	small molecule	B01AB06	9041-08-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26850	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Anninos H (2009)	19465361	182109	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26851	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Zhang W (2005)	15678110	181880	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26852	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Gomez-Isla T (2008)	18317243	182067	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26853	110857	4790	-	NFKB1	EBP-1|KBF1|NF-kB1|NF-kappa-B|NF-kappaB|NFKB-p105|NFKB-p50|NFkappaB|p105|p50	9606	Homo sapiens	antagonist	target	Whitehead SN (2007)	17194886	181980	7584	Triflusal	Triflusal	-	DRUGBANK	DB08814	C10H7F3O4	small molecule	B01AC18	322-79-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RMWVZGDJPAKBDE-UHFFFAOYSA-N
26905	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	inhibitor	target	Cozza G (2006)	16610779	181936	7605	Ellagic Acid	2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione|Benzoaric acid|Elagostasine|Lagistase|476-66-4|Alizarine Yellow	-	DRUGBANK	DB08846	C14H6O8	small molecule	-	476-66-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AFSDNFLWKVMVRB-UHFFFAOYSA-N
26906	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	inhibitor	target	Sekiguchi Y (2009)	19414254	182103	7605	Ellagic Acid	2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione|Benzoaric acid|Elagostasine|Lagistase|476-66-4|Alizarine Yellow	-	DRUGBANK	DB08846	C14H6O8	small molecule	-	476-66-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AFSDNFLWKVMVRB-UHFFFAOYSA-N
26908	111553	5566	-	PRKACA	PKACA	9606	Homo sapiens	inhibitor, competitive	target	Wang BH (1998)	9581512	181727	7605	Ellagic Acid	2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione|Benzoaric acid|Elagostasine|Lagistase|476-66-4|Alizarine Yellow	-	DRUGBANK	DB08846	C14H6O8	small molecule	-	476-66-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AFSDNFLWKVMVRB-UHFFFAOYSA-N
26942	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	inhibitor	target	Yang LP (2012)	23061804	182213	7621	Ruxolitinib	INCB424|INCB018424	jakafi|jakavi	DRUGBANK	DB08877	C17H18N6	small molecule	L01XE18	941678-49-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFNKQEVNSGCOJV-OAHLLOKOSA-N
26943	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	inhibitor	target	Cervantes F (2013)	23514013	182236	7621	Ruxolitinib	INCB424|INCB018424	jakafi|jakavi	DRUGBANK	DB08877	C17H18N6	small molecule	L01XE18	941678-49-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFNKQEVNSGCOJV-OAHLLOKOSA-N
26944	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	inhibitor	target	Yang LP (2012)	23061804	182213	7621	Ruxolitinib	INCB424|INCB018424	jakafi|jakavi	DRUGBANK	DB08877	C17H18N6	small molecule	L01XE18	941678-49-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFNKQEVNSGCOJV-OAHLLOKOSA-N
26945	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	inhibitor	target	Cervantes F (2013)	23514013	182236	7621	Ruxolitinib	INCB424|INCB018424	jakafi|jakavi	DRUGBANK	DB08877	C17H18N6	small molecule	L01XE18	941678-49-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFNKQEVNSGCOJV-OAHLLOKOSA-N
26951	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	binder	target	Browning DJ (2012)	22813448	182207	7629	Aflibercept	VEGF Trap|Ziv-Aflibercept|VEGF Trap-Eye	eylea|zaltrap	DRUGBANK	DB08885	C4318H6788N1164O1304S32	biologic	L01XX44|S01LA05	862111-32-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
26965	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	inhibitor	target	O'Hare T (2009)	19878872	182132	7645	Ponatinib	AP24534|AP 24534|Ponatinibum	iclusig	DRUGBANK	DB08901	C29H27F3N6O	small molecule	L01XE24	943319-70-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHXJVRSECIGDHY-UHFFFAOYSA-N
26967	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	inhibitor	target	Gozgit JM (2013)	23468082	182234	7645	Ponatinib	AP24534|AP 24534|Ponatinibum	iclusig	DRUGBANK	DB08901	C29H27F3N6O	small molecule	L01XE24	943319-70-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHXJVRSECIGDHY-UHFFFAOYSA-N
26989	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	inhibitor	target	Salama AK (2013)	23432625	182233	7655	Trametinib	JTP 74057|GSK 1120212|Trametinib Dimethyl Sulfoxide|Trametinibum	mekinist	DRUGBANK	DB08911	C26H23FIN5O4	small molecule	L01XE25	871700-17-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LIRYPHYGHXZJBZ-UHFFFAOYSA-N
26990	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Salama AK (2013)	23432625	182233	7655	Trametinib	JTP 74057|GSK 1120212|Trametinib Dimethyl Sulfoxide|Trametinibum	mekinist	DRUGBANK	DB08911	C26H23FIN5O4	small molecule	L01XE25	871700-17-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LIRYPHYGHXZJBZ-UHFFFAOYSA-N
27364	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	inhibitor	target	Singh A (2015)	26384788	188510	5018	Cobimetinib	-	cotellic	DRUGBANK	DB05239	C21H21F3IN3O2	small molecule	-	934660-93-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BSMCAPRUBJMWDF-KRWDZBQOSA-N
27375	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1998)	9850732	172163	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27376	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (2001)	11327694	172166	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27377	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Locci P (1995)	7648625	172165	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27378	112898	7040	-	TGFB1	CED|DPD1|LAP|TGFB|TGFbeta	9606	Homo sapiens	inhibitor	target	Chang NS (1997)	9435505	172164	7766	Hyaluronidase (Human Recombinant)	Hyaluronidase recombinant human|Recombinant human hyaluronidase	hylenex recombinant	DRUGBANK	DB06205	-	biologic	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27457	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antagonist	target	van Zaanen HC (1996)	8823310	188534	7799	Siltuximab	-	sylvant	DRUGBANK	DB09036	C6450H9932N1688O2016S50	biologic	L04AC11	541502-14-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27458	109783	3569	-	IL6	BSF2|HGF|HSF|IFNB2|IL-6	9606	Homo sapiens	antibody	target	van Zaanen HC (1996)	8823310	188534	7799	Siltuximab	-	sylvant	DRUGBANK	DB09036	C6450H9932N1688O2016S50	biologic	L04AC11	541502-14-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27477	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	inhibitor	target	Fry DW (2004)	15542782	188549	7820	Palbociclib	6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one	ibrance	DRUGBANK	DB09073	C24H29N7O2	small molecule	L01XE33	571190-30-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHJRHEGDXFFMBM-UHFFFAOYSA-N
27478	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	inhibitor	target	Fry DW (2004)	15542782	188549	7820	Palbociclib	6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one	ibrance	DRUGBANK	DB09073	C24H29N7O2	small molecule	L01XE33	571190-30-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHJRHEGDXFFMBM-UHFFFAOYSA-N
27490	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	inhibitor	target	Matsui J (2008)	17943726	188553	7825	Lenvatinib	4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide|Lenvatinib Mesylate	lenvima	DRUGBANK	DB09078	C21H19ClN4O4	small molecule	L01XE29	417716-92-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WOSKHXYHFSIKNG-UHFFFAOYSA-N
27498	108552	2261	-	FGFR3	ACH|CD333|CEK2|HSFGFR3EX|JTK4	9606	Homo sapiens	inhibitor	target	Hilberg F (2008)	18559524	188554	7826	Nintedanib	methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate	ofev	DRUGBANK	DB09079	C31H33N5O4	small molecule	L01XE31	656247-17-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XZXHXSATPCNXJR-ZIADKAODSA-N
27502	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	inhibitor	target	Hilberg F (2008)	18559524	188554	7826	Nintedanib	methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate	ofev	DRUGBANK	DB09079	C31H33N5O4	small molecule	L01XE31	656247-17-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XZXHXSATPCNXJR-ZIADKAODSA-N
27670	112954	7099	-	TLR4	ARMD10|CD284|TLR-4|TOLL	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	8062	Lauric Acid	Dodecanoic acid|N-dodecanoic acid|DAO|Coconut oil fatty acids|Undecane-1-carboxylic acid|Duodecylic acid|Dodecylic acid|C12:0|Dodecanoate|C12 fatty acid|ABL|Dodecylcarboxylate|Laurinsaeure|1-Undecanecarboxylic acid|N-dodecanoate|Laurostearic acid|Dodecoic acid|Vulvic acid|Duodecyclic acid	vitafol plus	DRUGBANK	DB03017	C12H24O2	small molecule	-	143-07-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	POULHZVOKOAJMA-UHFFFAOYSA-N
27698	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Beckers T (2007)	17455259	182004	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27701	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	inhibitor	target	Beckers T (2007)	17455259	182004	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27704	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	7605	Ellagic Acid	2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione|Benzoaric acid|Elagostasine|Lagistase|476-66-4|Alizarine Yellow	-	DRUGBANK	DB08846	C14H6O8	small molecule	-	476-66-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AFSDNFLWKVMVRB-UHFFFAOYSA-N
27767	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Heal DJ (2013)	23539642	196018	175	Amphetamine	beta-Phenylisopropylamine|-methylbenzeneethaneamine|Amphetamin|Amfetaminum|beta-Phenylisopropylamin|alpha-Methylbenzeneethaneamine|1-Phenylpropan-2-amin|1-phenyl-2-aminopropane|-methylphenethylamine|rac-(2R)-1-phenylpropan-2-amine|Desoxynorephedrine|alpha-Methylphenylethylamine|beta-Aminopropylbenzene|-phenylisopropylamine|rac-amphetamine|Amphetamine|-aminopropylbenzene|Amfetamine	pms-amphetamines xr|act amphet	DRUGBANK	DB00182	C9H13N	small molecule	N06BA01	300-62-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWTSXDURSIMDCE-UHFFFAOYSA-N
27822	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	VanderMolen KM (2011)	21587264	196007	8066	Romidepsin	chromodax|istodax	istodax	DRUGBANK	DB06176	C24H36N4O6S2	small molecule	L01XX39	128517-07-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QDBHDZETSA-N
27825	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	inhibitor	target	VanderMolen KM (2011)	21587264	196007	8066	Romidepsin	chromodax|istodax	istodax	DRUGBANK	DB06176	C24H36N4O6S2	small molecule	L01XX39	128517-07-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QDBHDZETSA-N
27826	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	antagonist	target	VanderMolen KM (2011)	21587264	196007	8066	Romidepsin	chromodax|istodax	istodax	DRUGBANK	DB06176	C24H36N4O6S2	small molecule	L01XX39	128517-07-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QDBHDZETSA-N
27840	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Gruber C (2004)	15535430	195962	7770	Bazedoxifene	bazedoxifene/conjugated estrogens	duavee|duavive	DRUGBANK	DB06401	C30H34N2O3	small molecule	G03XC02|G03CC07	198481-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UCJGJABZCDBEDK-UHFFFAOYSA-N
27841	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	antagonist	target	Gruber C (2004)	15535430	195962	7770	Bazedoxifene	bazedoxifene/conjugated estrogens	duavee|duavive	DRUGBANK	DB06401	C30H34N2O3	small molecule	G03XC02|G03CC07	198481-32-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UCJGJABZCDBEDK-UHFFFAOYSA-N
27866	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Geng L (2006)	17145876	195973	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27869	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	inhibitor	target	Geng L (2006)	17145876	195973	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27905	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	agonist	target	Escande A (2009)	19464167	195991	8113	Tibolone	17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one|tibolona|tibolonum	-	DRUGBANK	DB09070	C21H28O2	small molecule	G03CX01	5630-53-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WZDGZWOAQTVYBX-XOINTXKNSA-N
27930	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	inhibitor	target	Yosaatmadja Y (2015)	26522274	196035	8129	Osimertinib	N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide|Mereletinib	tagrisso	DRUGBANK	DB09330	C28H33N7O2	small molecule	-	1421373-65-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DUYJMQONPNNFPI-UHFFFAOYSA-N
27933	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	antagonist	target	Kuenen B (2010)	20197484	195996	8209	Necitumumab	-	portrazza	DRUGBANK	DB09559	-	biologic	L01XC22	906805-06-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27935	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Souers AJ (2013)	23291630	196015	8250	Venetoclax	4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro-4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide	venclexta	DRUGBANK	DB11581	C45H50ClN7O7S	small molecule	-	1257044-40-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LQBVNQSMGBZMKD-UHFFFAOYSA-N
27936	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor	target	Davids MS (2013)	23410971	196016	8250	Venetoclax	4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro-4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide	venclexta	DRUGBANK	DB11581	C45H50ClN7O7S	small molecule	-	1257044-40-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LQBVNQSMGBZMKD-UHFFFAOYSA-N
27982	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Kraft SL (2014)	24038727	198172	1156	Procarbazine	Procarbazinum|p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide|N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide|N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine|1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine|Procarbazin|Procarbazina|N-Isopropyl--(2-methylhydrazino)-p-toluamide|2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine|N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide|4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide|N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide	matulane	DRUGBANK	DB01168	C12H19N3O	small molecule	L01XB01	671-16-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPTBDICYNRMXFX-UHFFFAOYSA-N
27983	110301	4128	RP1-201D17__B.2	MAOA	MAO-A	9606	Homo sapiens	inhibitor	target	Holt A (1992)	1359073	198173	1156	Procarbazine	Procarbazinum|p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide|N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide|N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine|1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine|Procarbazin|Procarbazina|N-Isopropyl--(2-methylhydrazino)-p-toluamide|2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine|N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide|4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide|N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide	matulane	DRUGBANK	DB01168	C12H19N3O	small molecule	L01XB01	671-16-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CPTBDICYNRMXFX-UHFFFAOYSA-N
28012	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8426	Bivalent ligand 1	Bivalent_ligand_1|SNIPER 11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 11(cIAP1:BE04 --- AR:DHT)	-
28014	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2010)	20369832	125335	8428	Bivalent ligand 2	Bivalent_ligand_2|Compound 4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	107772	1381	-	CRABP1	CRABP|CRABP-I|CRABPI|RBP5	9606	Homo sapiens	target	Standardized BVL Name: Compound 4b(cIAP1:methyl bestatin --- CRABPI/II:ATRA)	-
28016	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang W (2017)	28542609	211389	8428	Bivalent ligand 2	Bivalent_ligand_2|Compound 4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 4b(cIAP1:methyl bestatin --- CRABP-I/II:ATRA)	-
28018	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8427	Bivalent ligand 3	Bivalent_ligand_3|SNIPER 13	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 13(cIAP1:BE04 --- ER:estrone)	-
28020	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	22014751	142167	8423	Bivalent ligand 4	Bivalent_ligand_4|SNIPER 9	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	111849	5914	-	RARA	NR1B1|RAR	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 9(cIAP1:BE04 --- RAR:Ch55)	-
28023	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	degradation	target	Ohoka N (2014)	25375378	206180	8422	Bivalent ligand 5	Bivalent_ligand_5|SNIPER(TACC3)-1/SNIPER(TACC3)-2|SNIPER(TACC3)-1|SNIPER(TACC3)-2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(TACC3)-1(cIAP1:bestatin --- TACC3:KHS108)	-
28024	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Henning RK (2016)	26880702	211388	8425	Bivalent ligand 6	Bivalent_ligand_6|CPP-tri_a-PR	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: CPP-tri_a-PR(VHL:HIF1a peptide --- Akt:synthetic peptide)	-
28028	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Schneekloth JS (2004)	15038727	211349	8421	Bivalent ligand 8	Bivalent_ligand_8|PROTAC 5|Protac-5	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-5 (VHL:HIF1a-polyarginine peptide sequence --- AR:DHT)	-
28032	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Lee H (2007)	17907127	211396	8450	Bivalent ligand 10	Bivalent_ligand_10|Api-Protac-II	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106699	196	-	AHR	bHLHe76	9606	Homo sapiens	target	Standardized BVL Name: ApiProtac-II(VHL:HIF1a pentapeptide --- AR:apigenin)	-
28034	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Lai AC (2016)	26593377	191787	8449	Bivalent ligand 11	Bivalent_ligand_11|DAS-VHL	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DAS-VHL(VHL:HIF-1alpha hydroxyproline derived small molecule --- c-ABL:dasatinib)	-
28040	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Demizu Y (2016)	27666635	199362	8451	Bivalent ligand 13	Bivalent_ligand_13|SNIPER(ABL)2,3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ABL)2,3(cIAP1:methyl bestatin --- BCR-ABL:imatinib derivative)	-
28042	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD2:triazolo-diazepine acetamide BET-binding moiety)	-
28044	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD3:triazolo-diazepine acetamide BET-binding moiety)	-
28046	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD4:triazolo-diazepine acetamide BET-binding moiety)	-
28048	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD2:JQ1)	-
28050	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113715	8019	RP11-374P20.3	BRD3	ORFX|RING3L	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- -BRD3:JQ1)	-
28052	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28055	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Winter GE (2015)	25999370	211411	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28057	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Lu J (2015)	26051217	211422	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28058	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2015)	26075522	211358	8448	Bivalent ligand 16	Bivalent_ligand_16|PROTAC_ERRa	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108405	2101	-	ESRRA	ERR1|ERRa|ERRalpha|ESRL1|NR3B1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC_ERRalpha(VHL:HIF-1alpha hydroxyproline derived small molecule --- ERRa:thiazolidinedione-based compound 29)	-
28061	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Sakamoto KM (2003)	14525958	111475	8447	Bivalent ligand 17	Bivalent_ligand_17|Protac-2|Protac 2	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114457	8945	RP11-529I10.2	BTRC	BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: Protac-2(Beta-TrCP:IkBalpha phosphopeptide --- ER:estradiol)	-
28062	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8458	Bivalent ligand 18	Bivalent_ligand_18|Protac-B	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: Protac-B(VHL:HIF1a pentapeptide --- ER:estradiol)	-
28064	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Cyrus K (2010)	20572252	211420	8457	Bivalent ligand 19	Bivalent_ligand_19|PROTAC 5	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5(VHL:HIF1a pentapeptide --- ER:estradiol (2 molecules))	-
28066	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Demizu Y (2012)	22277276	211397	8412	Bivalent ligand 20	Bivalent_ligand_20|SNIPER (ER) 5,6,7	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER (ER) 5,6,7(cIAP1:bestatin --- ER:4-hydroxytamoxifen)	-
28068	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2013)	23992566	211367	8413	Bivalent ligand 21	Bivalent_ligand_21|SNIPER(ER)-3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(ER)-3(cIAP1:methyl bestatin  --- ER:4-hydroxytamoxifen)	-
28072	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2012)	22658364	211406	8414	Bivalent ligand 22	Bivalent_ligand_22|Compound 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 6(IAP pan-ligand:MV-1  --- CRABP-II: ATRA)	-
28074	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2012)	22658364	211406	8414	Bivalent ligand 22	Bivalent_ligand_22|Compound 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: Compound 6(IAP pan-ligand:MV-1 --- CRABP-II: ATRA)	-
28077	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Ohoka N (2017)	28154167	211362	8415	Bivalent ligand 23	Bivalent_ligand_23|SNIPER(ER)-87	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(ER)-87(XIAP:LCL161 --- ER:4-hydroxytamoxifen)	-
28079	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ohoka N (2017)	28154167	211362	8416	Bivalent ligand 24	Bivalent_ligand_24|SNIPER(BRD4)-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(BRD4)-1(XIAP:LCL161 --- BRD4:JQ1)	-
28084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8419	Bivalent ligand 27	Bivalent_ligand_27|Protac-A	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Protac-A(VHL:HIF1a pentapeptide --- AR:DHT)	-
28086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Rodriguez-Gonzalez A (2008)	18794799	85962	8409	Bivalent ligand 28	Bivalent_ligand_28|Protac-AA	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Protac-AA(VHL:HIF1a pentapeptide+a polyarginine tail and two glycine residues  --- AR:DHT)	-
28090	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Hines J (2013)	23674677	194582	8460	Bivalent ligand 30	Bivalent_ligand_30|TrkAPPFRS2a|phosphoPROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116031	10818	-	FRS2	FRS2A|FRS2alpha|SNT|SNT-1|SNT1	9606	Homo sapiens	target	Standardized BVL Name: TrkAPPFRS2alpha(VHL:HIF1alpha septapeptide --- FRS2a:phosphorylated TrkA-derived decapeptide sequence)	-
28094	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang D (2004)	14741260	211348	8432	Bivalent ligand 32	Bivalent_ligand_32|Fu-SMPI	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116184	10988	-	METAP2	MAP2|MNPEP|p67|p67eIF2	9606	Homo sapiens	target	Standardized BVL Name: Fu-SMPI(VHL:HIF-1alpha octapeptide --- MetAP-2:fumagillol)	-
28096	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang D (2004)	14741260	211348	8411	Bivalent ligand 33	Bivalent_ligand_33|E2-SMPI/E2-octa|E2-SMPI|E2-octa	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: E2-SMPI/E2-octa(VHL:HIF-1alpha octapeptide --- ER:estradiol)	-
28098	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bargagna-Mohan P (2005)	15876533	211350	8456	Bivalent ligand 34	Bivalent_ligand_34|E2-penta	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: E2-penta(VHL:HIF-1alpha pentapeptide --- ER:estradiol)	-
28100	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Hines J (2013)	23674677	194582	8455	Bivalent ligand 35	Bivalent_ligand_35|ErbB2PPPI3K|phosphoPROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111313	5295	-	PIK3R1	AGM7|GRB1|IMD36|p85|p85-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: ErbB2PPPI3K(VHL:HIF1alpha septapeptide --- PI3K:ErbB3 peptide)	-
28102	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2015)	26075522	211358	8454	Bivalent ligand 36	Bivalent_ligand_36|PROTAC_RIPK2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC_RIPK2(VHL: HIF-1alpha hydroxyproline derived small molecule --- RIPK2:vandetanib)	-
28104	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Chu TT (2016)	27105281	211375	8453	Bivalent ligand 37	Bivalent_ligand_37|TH006	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: TH006(VHL:HIF1a peptide --- Tau:Beta-tubulin peptide)	-
28106	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Itoh Y (2011)	21515062	211395	8404	Bivalent ligand 38	Bivalent_ligand_38|SNIPER 6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107772	1381	-	CRABP1	CRABP|CRABP-I|CRABPI|RBP5	9606	Homo sapiens	target	Standardized BVL Name: SNIPER 6(cIAP-I:BE04- --- CRABP-I:ATRA)	-
28108	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Wang X (2016)	27473774	211351	8403	Bivalent ligand 40	Bivalent_ligand_40|PROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110263	4088	-	SMAD3	HSPC193|HsT17436|JV15-2|LDS1C|LDS3|MADH3	9606	Homo sapiens	target	Standardized BVL Name: (VHL:HIF1a peptide --- SMAD3:#8 SMC (EN300-72284))	-
28110	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8436	Bivalent ligand 41	Bivalent_ligand_41|SNIPER(CRABP)-4	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-4(cIAP1:methyl bestatin --- CRABP-II:ATRA)	-
28112	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8401	Bivalent ligand 42	Bivalent_ligand_42|SNIPER(CRABP)-11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	-
28114	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited E3 ligase	Okuhira K (2017)	27965304	207511	8401	Bivalent ligand 42	Bivalent_ligand_42|SNIPER(CRABP)-11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107773	1382	RP11-66D17.4	CRABP2	CRABP-II|RBP6	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	-
28118	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2015)	26338696	191691	8399	Bivalent ligand 48	Bivalent_ligand_48|compound 1b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	107775	1385	-	CREB1	CREB	9606	Homo sapiens	target	Standardized BVL Name: compound 1b(cIAP1:BE04 --- HaloTag-CREB1)	-
28120	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2015)	26338696	191691	8399	Bivalent ligand 48	Bivalent_ligand_48|compound 1b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	109928	3725	-	JUN	AP-1|AP1|c-Jun	9606	Homo sapiens	target	Standardized BVL Name: compound 1b(cIAP1:BE04 --- HaloTag-c-jun)	-
28122	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2016)	27236416	205947	8400	Bivalent ligand 49	Bivalent_ligand_49|Compound 4a/4b|Compound 4a|Compound 4b|4a|4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	112979	7124	DADB-70P7.1	TNF	DIF|TNF-alpha|TNFA|TNFSF2	9606	Homo sapiens	target	Standardized BVL Name: Compound 4a/4b(IAP pan-ligand:MV1 --- HaloTag-TNFalpha)	-
28124	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited E3 ligase	Tomoshige S (2016)	27236416	205947	8400	Bivalent ligand 49	Bivalent_ligand_49|Compound 4a/4b|Compound 4a|Compound 4b|4a|4b	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	107433	998	RP1-224A6.5	CDC42	CDC42Hs|G25K	9606	Homo sapiens	target	Standardized BVL Name: Compound 4a/4b(IAP pan-ligand:MV1 --- HaloTag-Cdc42)	-
28126	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-ERK1)	-
28128	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Buckley DL (2015)	26070106	211383	8438	Bivalent ligand 50	Bivalent_ligand_50|HaloPROTAC3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC3(VHL:degradation moiety B --- HaloTag7-MEK1)	-
28134	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Zhang X (2018)	29581547	211371	8443	Bivalent ligand 57	Bivalent_ligand_57|ARV-763	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: ARV-763 (VHL: :HIF-1alpha hydroxyproline derived small molecule --- BRD4:OTX015)	-
28138	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 1(VHL:Ligand 9 --- EGFR:lapatinib)	-
28140	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8439	Bivalent ligand 53	Bivalent_ligand_53|COMPOUND 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 3(VHL:Ligand 9 --- EGFR:gefitinib)	-
28142	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8442	Bivalent ligand 54	Bivalent_ligand_54|COMPOUND 3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: compound 4(VHL:Ligand 9 --- EGFR:afatinib)	-
28144	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8440	Bivalent ligand 52	Bivalent_ligand_52|MS4077|MS4078|COMPOUND 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108376	2064	-	ERBB2	CD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1	9606	Homo sapiens	target	Standardized BVL Name: compound 1(VHL:Ligand 9--- HER2:lapatinib)	-
28146	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Burslem GM (2018)	29129716	211414	8441	Bivalent ligand 55	Bivalent_ligand_55|Compound 7	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: compound 7(VHL:Ligand 9 --- c-Met:foretinib)	-
28148	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Jiang Y (2018)	29271628	211419	8405	Bivalent ligand 60	Bivalent_ligand_60|TD-PROTAC	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: TD-PROTAC(VHL:HIF1a pentapeptide --- ER: stabilized peptide TD-PERM)	-
28152	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Maniaci C (2017)	29018234	209238	8434	Bivalent ligand 59	Bivalent_ligand_59|CM9|CM10|CM11	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: CM9/CM10/CM11(VHL:Ligand 7 --- VHL:Ligand 7)	-
28155	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Winter GE (2017)	28673542	211369	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: dBET6(CRBN:thalidomide --- BRD4:JQ1)	-
28158	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Gadd MS (2017)	28288108	210014	8430	Bivalent ligand 62	Bivalent_ligand_62|AT-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: AT-1 (VHL:modified VH032 --- BRD4:JQ1)	-
28160	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114300	8767	WUGSC:H_RG437L15.1	RIPK2	CARD3|CARDIAK|CCK|GIG30|RICK|RIP2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1 (VHL: VHL ligand --- RIPK2: foretinib)	-
28162	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPK14:foretinib)	-
28164	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122928	79837	-	PIP4K2C	PIP5K2C	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- PIP4K2C:foretinib)	-
28166	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MET:foretinib)	-
28168	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- EPHB2:foretinib)	-
28170	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MARK4:foretinib)	-
28172	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108364	2050	-	EPHB4	HTK|MYK1|TYRO11	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- EPHB4:foretinib)	-
28174	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK3:foretinib)	-
28176	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	570722	645745	-	MT1HL1	MT1P2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MT1HL1:foretinib)	-
28178	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110447	4301	-	MLLT4	AF6	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MLLT4:foretinib)	-
28180	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124910	92106	-	OXNAD1	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- OXNAD1:foretinib)	-
28182	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109905	3699	-	ITIH3	H3P	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ITIH3:foretinib)	-
28184	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108336	2021	-	ENDOG	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ENDOG:foretinib)	-
28186	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124429	85014	-	TMEM141	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- TMEM141:foretinib)	-
28188	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108176	1843	-	DUSP1	CL100|HVH1|MKP-1|MKP1|PTPN10	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- DUSP1:foretinib)	-
28190	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122671	79446	-	WDR25	C14orf67	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- WDR25:foretinib)	-
28192	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122312	64834	CGI-88	ELOVL1	Ssc1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ELOVL1:foretinib)	-
28194	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114837	9447	RP11-520H16.3	AIM2	PYHIN4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- AIM2:foretinib)	-
28196	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK2:foretinib)	-
28198	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABL2:foretinib)	-
28200	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAP4K5:foretinib)	-
28202	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113703	7994	-	KAT6A	MOZ|MYST3|RUNXBP2|ZC2HC6A|ZNF220	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- KAT6A:foretinib)	-
28204	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121967	63874	-	ABHD4	ABH4	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABHD4:foretinib)	-
28206	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127816	162417	-	NAGS	AGAS|ARGA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- NAGS:foretinib)	-
28208	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121661	57614	-	KIAA1468	HsT3308|HsT885	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- KIAA1468:foretinib)	-
28210	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109833	3621	RP11-8D7.1	ING1	p24ING1c|p33|p33ING1|p33ING1b|p47|p47ING1a	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ING1:foretinib)	-
28212	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109212	2957	-	GTF2A1	TF2A1|TFIIA|TFIIA-42|TFIIAL	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- GTF2A1:foretinib)	-
28214	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABL1:foretinib)	-
28216	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124728	90522	hCG_1785221	YIF1B	FinGER8	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- YIF1B:foretinib)	-
28218	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120295	54957	-	TXNL4B	DLP|Dim2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- TXNL4B:foretinib)	-
28220	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited E3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122589	79172	-	CENPO	CENP-O|ICEN-36|MCM21R	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- CENPO:foretinib)	-
28394	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Soucy TA (2009)	19360080	209255	8353	Pevonedistat	MLN4924|MLN 4924|[(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl]methyl sulfamate|Pevonedistat|[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate|S3AZD8D215|9605|MLN4924	-	CHEMSPIDER	17625129	C21H25N5O4S	small molecule	-	905579-51-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MPUQHZXIXSTTDU-QXGSTGNESA-N
28406	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Nepal M (2012)	22760073	211412	8361	Bavachinin	2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one|4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-|2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-on|2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one|2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydro-4H-chromen-4-one|Bavachinin A	-	CHEMSPIDER	109499	C21H22O4	small molecule	-	19879-30-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VOCGSQHKPZSIKB-UHFFFAOYSA-N
28407	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	22369643	131566	8362	(4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE	(4r)-4-Hydroxy-1-[(3-Methylisoxazol-5-Yl)acetyl]-N-[4-(1,3-Oxazol-5-Yl)benzyl]-L-Prolinamide|2-Pyrrolidinecarboxamide, 4-hydroxy-1-[2-(3-methyl-5-isoxazolyl)acetyl]-N-[[4-(5-oxazolyl)phenyl]methyl]-, (2S,4R)-|(4R)-4-Hydroxy-1-[(3-methyl-1,2-oxazol-5-yl)acetyl]-N-[4-(1,3-oxazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	31133666	C21H22N4O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HFCLIEBJTGJKSV-AEFFLSMTSA-N
28408	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Galdeano C (2014)	25166285	167549	8363	(2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	L-Prolinamide, N-acetyl-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-|N-Acetyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	35035176	C24H32N4O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFVIEZBZIUKYOG-SVFBPWRDSA-N
28409	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Soares P (2018)	28853884	211366	8364	VH298	-	-	CHEMSPIDER	58804244	C54H66N10O8S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GYJMGEJLYDLYLJ-IUVJQGSXSA-N
28410	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Frost J (2016)	27811928	211370	8364	VH298	-	-	CHEMSPIDER	58804244	C54H66N10O8S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GYJMGEJLYDLYLJ-IUVJQGSXSA-N
28411	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	23065727	148591	8365	(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide	(2s,4r)-1-(2-Chlorophenyl)carbonyl-N-[(4-Chlorophenyl)methyl]-4-Oxidanyl-Pyrrolidine-2-Carboxamide|2-Pyrrolidinecarboxamide, 1-(2-chlorobenzoyl)-N-[(4-chlorophenyl)methyl]-4-hydroxy-, (2S,4R)-|(4R)-1-(2-Chlorobenzoyl)-N-(4-chlorobenzyl)-4-hydroxy-L-prolinamide	-	CHEMSPIDER	35034462	C19H18Cl2N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	POSPLUDREYFAQC-PBHICJAKSA-N
28412	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	inhibitor	target	Buckley DL (2012)	23065727	148591	8366	(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide	(2s,4r)-1-(3-Amino-2-Methylbenzoyl)-4-Hydroxy-N-(4-(4-Methylthiazol-5-Yl)benzyl)pyrrolidine-2-Carboxamide|2-Pyrrolidinecarboxamide, 1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-|(4R)-1-(3-Amino-2-methylbenzoyl)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide	-	CHEMSPIDER	34258861	C24H26N4O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AFUSGLDYQSDIEU-NQIIRXRSSA-N
28417	113185	7337	-	UBE3A	ANCR|AS|E6-AP|EPVE6AP|HPVE6A	9606	Homo sapiens	inhibitor	target	Rossi M (2014)	24787015	211402	1230	Clomipramine	Clomipraminum|3-Chloroimipramine|Monochlorimipramine|3-(3-chloro-10,11-dihydro-5H-Dibenzo[b,F]azepin-5-yl)-N,N-dimethyl-1-propanamine|Clomipramine|Clomipramina|g 34586|Chlorimipramine|3-(3-CHLORO-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine	gen-clomipramine - tab 50mg|pm	DRUGBANK	DB01242	C19H23ClN2	small molecule	N06AA04	303-49-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GDLIGKIOYRNHDA-UHFFFAOYSA-N
28429	107116	648	RP11-573G6.1	BMI1	FLVI2/BMI1|PCGF4|RNF51	9606	Homo sapiens	inhibitor	target	Alchanati I (2009)	19956605	124271	8378	PRT4165	2-Pyridin-3-ylmethylene-indan-1,3-dione|PRT-4165|J625FJL5DX|2-(Pyridin-3-ylmethylene)-1H-indene-1,3(2H)-dione|1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-|2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione	-	CHEMSPIDER	180156	C15H9NO2	small molecule	-	31083-55-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OMHZFEWYVFWVLI-UHFFFAOYSA-N
28437	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	An H (2015)	28717502	211368	8341	ABP-A3	N-(3-Ethynylphenyl)-5'-O-sulfamoyladenosine|Adenosine, 5'-O-(aminosulfonyl)-N-(3-ethynylphenyl)-	-	CHEMSPIDER	57643654	C18H18N6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZNFQRSVDZCPTR-SCFUHWHPSA-N
28454	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28474	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28476	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Swords RT (2010)	20203261	211410	8353	Pevonedistat	MLN4924|MLN 4924|[(1S,2S,4R)-4-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl]methyl sulfamate|Pevonedistat|[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate|S3AZD8D215|9605|MLN4924	-	CHEMSPIDER	17625129	C21H25N5O4S	small molecule	-	905579-51-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MPUQHZXIXSTTDU-QXGSTGNESA-N
28483	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	inhibitor	target	Sodji Q (2014)	25240614	211381	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
28506	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Ward SJ (2018)	30228188	213502	1192	Mitoxantrone	Mitoxantrona|Mitoxantronum|Mitoxantrone|1,4-DIHYDROXY-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-anthracenedione	mitoxantrone injection|mitoxan	DRUGBANK	DB01204	C22H28N4O6	small molecule	L01DB07	65271-80-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KKZJGLLVHKMTCM-UHFFFAOYSA-N
28528	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor	target	Sun B (2018)	28663582	210027	8577	birabresib	OTX015|(S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide|MFCD26960949|birabresib|MK-8628|X40LKS49S3|10407|2-[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide|6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6S)-|OTX-015	-	CHEMSPIDER	8112374	C25H22ClN5O2S	small molecule	-	202590-98-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GNMUEVRJHCWKTO-FQEVSTJZSA-N
28545	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8594	BI8622	N-[4-(Aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-4-pyrimidinecarboxamide|4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-	-	CHEMSPIDER	75533993	C25H26N6O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IJHAXMJRQQTBPL-UHFFFAOYSA-N
28546	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8617	BI8626	1,3-Benzenedimethanamine, N~1~-[8-[4-(phenylmethyl)-1-piperazinyl]pyrimido[5,4-d]pyrimidin-4-yl]-|N-[3-(Aminomethyl)benzyl]-8-(4-benzyl-1-piperazinyl)pyrimido[5,4-d]pyrimidin-4-amine	-	CHEMSPIDER	75533990	C25H28N8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DZDNGSNKWIORRZ-UHFFFAOYSA-N
28547	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Senisterra G (2018)	29562800	213633	8584	NV03	Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-|N-[3-(Diethylamino)propyl]-2-(5,9-dimethyl-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)acetamide	-	CHEMSPIDER	78316460	C19H27N5O2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	NV03 is an antagonist of the UHRF1 - H3K9me3 interaction	KNZQAVKYBBYDKV-UHFFFAOYSA-N
28554	114465	8975	-	USP13	ISOT3|IsoT-3	9606	Homo sapiens	inhibitor	target	Shao S (2014)	24585095	223668	8614	Spautin-1	MFCD16962292|4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-|6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine|6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine|Spautin-1|C43	-	CHEMSPIDER	25199963	C15H11F2N3	small molecule	-	1262888-28-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AWIVHRPYFSSVOG-UHFFFAOYSA-N
28575	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Li H (2018)	30181285	215711	8612	D19	2-[(E)-(1,3-Benzothiazol-2-ylhydrazono)methyl]-1-benzothiophene-3-ol|Benzo[b]thiophene-2-carboxaldehyde, 3-hydroxy-, 2-(2-benzothiazolyl)hydrazone	-	CHEMSPIDER	88294931	C16H11N3OS2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NJUBGVFAHILBQL-RQZCQDPDSA-N
28577	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhou B (2018)	28339196	211345	8466	Bivalent ligand 39	BETd-260|Bivalent_ligand_39	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BETd-260(CRBN:thalidomide --- BDR4:HJB97 (compound 8))	-
28583	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Yang K (2018)	29871848	223608	8529	Bivalent ligand 46	dHDAC6|Bivalent_ligand_46	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dHDAC6(CRBN:pomalidomide --- HDAC6:pan-HDAC inhibitor AB3)	-
28586	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Testa A (2018)	29949369	213521	8431	Bivalent ligand 65	Bivalent_ligand_65|PROTAC 15a	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 15a (VHL: F-Hyp-containing HIF-1 epitope peptide --- BRD4:JQ1)	-
28591	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Qin C (2018)	30019901	215015	8497	Bivalent ligand 67	QCA570|Bivalent_ligand_67	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: QCA570 (CRBN:thalidomide --- BDR4: QCA276 (BET inhibitor 22))	-
28598	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2019)	30672516	223610	8510	Bivalent ligand 71	CRBN-6-5-5-VHL|Bivalent_ligand_71	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: (VHL:VH298 ---CRBN:pomalidomide)	-
28600	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	8512	Bivalent ligand 72	SJFa PROTAC|Bivalent_ligand_72	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	target	SJFalpha PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28602	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	8511	Bivalent ligand 73	SJFd PROTAC|Bivalent_ligand_73	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	target	SJFDelta PROTAC|Standardized BVL Name: (VHL:ligand 7 ---MAPK1:Foretinib)	-
28604	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2019)	30629437	223611	8514	Bivalent ligand 74	ARD-69|Bivalent_ligand_74	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	ARD-69|Standardized BVL Name: (VHL:VHL-e ---AR:enzalutamide)	-
28609	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Brand M (2019)	30595531	214853	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	BSJ-03-123|Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28613	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Rana S (2019)	30935795	215476	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: (CRBN:pomalidomide ---CDK6: palbociclib)	-
28615	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	DeMars KM (2019)	30872008	215612	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28617	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hines J (2019)	30385614	215621	8518	Bivalent ligand 78	A1874|Bivalent_ligand_78	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: A1874(MDM2:idasanutlin --- BRD4:JQ1)	-
28618	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Tinworth CP (2019)	30807093	215660	8517	Bivalent ligand 79	Protac 3|Bivalent_ligand_79	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107160	695	RP1-164F3.2	BTK	AGMX1|AT|ATK|BPK|IMD1|PSCTK1|XLA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3 ( CIAP1:piperazine --- BTK:ibrutinib)	-
28624	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8492	Bivalent ligand 84	Compound 1|Bivalent_ligand_84	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL: compound 15 --- EGFR:lapatinib)	-
28626	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8492	Bivalent ligand 84	Compound 1|Bivalent_ligand_84	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108376	2064	-	ERBB2	CD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1(VHL: compound 15 --- ERBB2:lapitinib)	-
28628	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	29129716	211414	8468	Bivalent ligand 85	Compound 7|Bivalent_ligand_85	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110391	4233	-	MET	AUTS9|HGFR|RCCP2|c-Met	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 7 (VHL: compound 15 --- MET:foretinib)	-
28630	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gechijian LN (2018)	29507391	223613	8494	Bivalent ligand 86	dTRIM24|Bivalent_ligand_86	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114333	8805	-	TRIM24	PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1	9606	Homo sapiens	target	Standardized BVL Name: dTRIM24 (VHL:VL-269 --- TRIM24:IACS-7e)	-
28636	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- SMARCA2:SMARCABD ligand)	-
28638	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- SMARCA4:SMARCABD ligand)	-
28640	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Farnaby W (2019)	31178587	223615	8485	Bivalent ligand 89	ACBI1|Bivalent_ligand_89	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120490	55193	-	PBRM1	BAF180|PB1	9606	Homo sapiens	target	Standardized BVL Name: ACBI1 (VHL:VH298 --- PBRM1:SMARCABD ligand)	-
28643	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Popow J (2019)	30739444	223616	8546	Bivalent ligand 90	BI-3663|Bivalent_ligand_90	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BI-3663 (CRBN:pomalidomide --- PTK2:BI-4464)	-
28647	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhang X (2019)	31209349	220534	8544	Bivalent ligand 92	KB02-JQ1|Bivalent_ligand_92	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	small molecule|Standardized BVL Name: KB02-JQ1 (DCAF16:KB02 --- BRD4:JQ1)	-
28648	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	30978004	220718	8543	Bivalent ligand 93	HaloPROTAC-E|Bivalent_ligand_93	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HaloTag7-SGK3)	-
28650	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	30978004	220718	8543	Bivalent ligand 93	HaloPROTAC-E|Bivalent_ligand_93	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	111307	5289	-	PIK3C3	VPS34|hVps34	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HaloTag7-PIK3C3)	-
28653	110338	4170	-	MCL1	BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT	9606	Homo sapiens	degradation	target	Wang Z (2019)	31389699	220719	8542	Bivalent ligand 94	PROTAC C3|Bivalent_ligand_94	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC C3 (CRBN:pomalidomide ---MCL1:Nap-1)	-
28655	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	degradation	target	Wang Z (2019)	31389699	220719	8504	Bivalent ligand 95	PROTAC C5|Bivalent_ligand_95	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC C5 (CRBN:pomalidomide ---BCL2:S1-6)	-
28658	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao Q (2019)	31539241	220727	8502	Bivalent ligand 97	SIAIS178|Bivalent_ligand_97	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: SIAIS178 (VHL:VHL1 --- BCR-ABL:dasatinib)	-
28662	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2019)	31311809	223347	8506	Bivalent ligand 100	GMB-475|Bivalent_ligand_100	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: GMB-475(VHL:VHL1 --- BCR-ABL1:GNF-5)	-
28664	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2018)	30427680	223617	8507	Bivalent ligand 101	FLT-3 PROTAC|Bivalent_ligand_101	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108610	2322	RP11-153M24.3	FLT3	CD135|FLK-2|FLK2|STK1	9606	Homo sapiens	target	Standardized BVL Name: FLT-3 PROTAC(VHL:VHL1 --- FLT3:quizartinib)	-
28666	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2019)	31730343	223618	8508	Bivalent ligand 102	MS432N|Bivalent_ligand_102	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS432N(VHL:VHL1 --- MAP2K1:PD0325901)	-
28668	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wei J (2019)	31730343	223618	8508	Bivalent ligand 102	MS432N|Bivalent_ligand_102	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS432N(VHL:VHL1 --- MAP2K2:PD0325901)	-
28672	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Tovell H (2019)	31461270	222512	8483	Bivalent ligand 104	SGK3-PROTAC1|Bivalent_ligand_104	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: SGK3-PROTAC1 (VHL:VH032 --- SGK3:308-R)	-
28674	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cromm PM (2018)	30444612	223619	8557	Bivalent ligand 105	PROTAC-3|Bivalent_ligand_105	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-3 (VHL:SAR --- PTK2:defactinib)	-
28676	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chan KH (2018)	28595007	223620	8539	Bivalent ligand 106	MZP-54|MZP-55|Bivalent_ligand_106	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: MZP-55 (VHL: --- BRD4:I-BET726)	-
28679	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chan KH (2018)	28595007	223620	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28680	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chan KH (2018)	28595007	223620	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28684	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Khan S (2019)	31792461	223622	8499	Bivalent ligand 108	DT2216|Bivalent_ligand_108	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: DT2216 (VHL:VHL-L --- BCL2L1:ABT263)	-
28687	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhang F (2020)	31813613	223623	8500	Bivalent ligand 109	compound 21|Bivalent_ligand_109	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 21 (CRBN:pomalidomide --- BRD4:compound 5)	-
28690	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chi JJ (2019)	31669221	222989	8469	Bivalent ligand 111	CP5V|Bivalent_ligand_111	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107427	991	-	CDC20	CDC20A|bA276H19.3|p55CDC	9606	Homo sapiens	target	Standardized BVL Name: CP5V (VHL:VHL1 --- CDC20:apcin-A)	-
28692	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zoppi V (2019)	30540463	223625	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD9: BRDL1)	-
28694	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zoppi V (2019)	30540463	223625	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118883	29117	-	BRD7	BP75|CELTIX1|NAG4	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD7: BRDL1)	-
28697	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Bai L (2019)	31715132	223626	8467	Bivalent ligand 113	SD-36|Bivalent_ligand_113	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SD-36 (CRBN:lenalidomide --- STAT3:SI-109)	-
28699	110338	4170	-	MCL1	BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT	9606	Homo sapiens	degradation	target	Papatzimas JW (2019)	31117518	220896	8571	Bivalent ligand 114	dMCL1-2|Bivalent_ligand_114	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dMCL1-2 (CRBN:4-hydroxythalidomide --- MCL1:A-1210477)	-
28700	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kim K (2019)	31873151	223627	8570	Bivalent ligand 115	TD-165|Bivalent_ligand_115	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: TD-165 (VHL:VHL032 --- CRBN:pomalidomide)	-
28704	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	BasuRay S (2019)	31019090	223628	8568	Bivalent ligand 117	PROTAC3|Bivalent_ligand_117	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	228103	116939	-	Pnpla3	Adpn	10090	Mus musculus	target	Standardized BVL Name: PROTAC3 (VHL:hydroxyproline derivative  --- Pnpla3:HaloTag)	-
28708	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Nunes J (2019)	31312412	223630	8486	Bivalent ligand 119	compound 9|Bivalent_ligand_119	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (VHL:VHL ligand --- IRAK4: PF-06650833)	-
28713	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- AURKA:TL13-87)	-
28715	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- PTK2:TL13-87)	-
28749	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
28751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
28755	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
28777	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Qiu X (2019)	31066567	223631	8533	Bivalent ligand 124	SIAIS213110|Bivalent_ligand_124	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS213110 (CRBN:lenalidomide --- BRD4:JQ1-acid)	-
28779	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8534	Bivalent ligand 125	JQ1-CLIPTAC|Bivalent_ligand_125	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JQ1-CLIPTAC (CRBN:Tz-thalidomide --- BRD4:JQ1)	-
28781	111581	5595	-	MAPK3	ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK3:Probe 1)	-
28783	111580	5594	-	MAPK1	ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8531	Bivalent ligand 126	ERK-CLIPTAC|Bivalent_ligand_126	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ERK-CLIPTAC (CRBN:Tz-thalidomide --- MAPK1:Probe 1)	-
28784	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2020)	32840532	223633	8532	Bivalent ligand 127	XZ9002|Bivalent_ligand_127	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: XZ9002 (VHL:VH032 --- HDAC3:SR-3558)	-
28790	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC1:CI-994)	-
28792	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC2:CI-994)	-
28794	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2020)	32201871	223636	8520	Bivalent ligand 130	compound 4|Bivalent_ligand_130	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL ligand --- HDAC3:CI-994)	-
28837	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Banik SM (2020)	32728216	223640	8526	Bivalent ligand 136	Ab-2|Bivalent_ligand_136	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	109703	3482	-	IGF2R	CD222|CIMPR|M6P-R|MPR1|MPRI	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: Ab-2 (IGF2R:M6Pn glycopolypeptide ligand --- EGFR:cetuximab)	-
28839	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Banik SM (2020)	32728216	223640	8525	Bivalent ligand 137	Ab-3|Bivalent_ligand_137	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	109703	3482	-	IGF2R	CD222|CIMPR|M6P-R|MPR1|MPRI	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: Ab-3 (IGF2R:M6Pn glycopolypeptide ligand --- CD274:PD-L1 antibody)	-
28840	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang M (2020)	32437146	223641	8528	Bivalent ligand 138	SHP2-D26|Bivalent_ligand_138	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: SHP2-D26 (VHL:VHL-1 ligand 6 --- PTPN11:compound 5)	-
28842	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Sun N (2020)	32179332	223642	8527	Bivalent ligand 139	SIAIS117|Bivalent_ligand_139	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106739	238	-	ALK	CD246|NBLST3	9606	Homo sapiens	target	Standardized BVL Name: SIAIS117 (VHL:VHL-1 --- ALK:brigatinib)	-
28847	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Mu X (2020)	31708096	223603	8559	Bivalent ligand 141	HBL-4|Bivalent_ligand_141	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HBL-4  (CRBN:thalidomide --- BRD4:BI2536)	-
28849	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Mu X (2020)	31708096	223603	8559	Bivalent ligand 141	HBL-4|Bivalent_ligand_141	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HBL-4  (CRBN:thalidomide --- PLK1:BI2536)	-
28863	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	degradation	target	Sievers QL (2018)	30385546	212829	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:pomalidomide ---ZNF692:pomalidomide)	-
28865	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	degradation	target	Sievers QL (2018)	30385546	212829	8561	Bivalent ligand 143	lenalidomide|Bivalent_ligand_143	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:lenalidomide ---ZNF692:lenalidomide)	-
28867	120789	55657	-	ZNF692	AREBP|Zfp692	9606	Homo sapiens	degradation	target	Sievers QL (2018)	30385546	212829	8562	Bivalent ligand 144	thalidomide|Bivalent_ligand_144	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Full length protein degraded in vivo|Standardized BVL Name: (CRBN:thalidomide ---ZNF692:thalidomide)	-
28886	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Crew AP (2018)	28692295	217494	8488	Bivalent ligand 80	PROTAC 3i|Bivalent_ligand_80	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3i (VHL:VHL ligand 2 ---TBK1:ligand 1b)	-
28890	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Shan Y (2020)	32750566	223645	8563	Bivalent ligand 145	PROTAC 5|Bivalent_ligand_145	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5(VHL:VH032 ---KDR:ABT-869)	-
28893	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Li L (2020)	32713946	223646	8564	Bivalent ligand 146	DP1|Bivalent_ligand_146	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DP1(DCAF15:E7820 --- BRD4:JQ1)	-
28898	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- ULK1-GFP:GFP-HaloTag)	-
28900	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	123547	81610	-	FAM83D	C20orf129|CHICA|dJ616B8.3	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- FAM83D-GFP:GFP-HaloTag)	-
28902	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117195	23678	-	SGK3	CISK|SGK2|SGKL	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- SGK3-GFP:GFP-HaloTag)	-
28904	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- HRAS:RASabHaloTag)	-
28906	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Simpson LM (2020)	32668203	223649	8567	Bivalent ligand 149	HaloPROTAC-E|Bivalent_ligand_149	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-E (VHL:VH298 --- KRAS:RASabHaloTag)	-
28908	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Barrios AM (2020)	32615037	223650	8550	Bivalent ligand 150	compound 26|Bivalent_ligand_150	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: compound 26 (VHL:VHL ligand --- PTPN11:SHP099)	-
28913	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donoghue C (2020)	32634680	223652	8548	Bivalent ligand 152	NR-7h|Bivalent_ligand_152	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NR-7h (CRBN:thalidomide --- MAPK14:PH-797804)	-
28918	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liao H (2020)	32550000	223654	8554	Bivalent ligand 154	xStAx-VHLL|Bivalent_ligand_154	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	target	Standardized BVL Name: xStAx-VHLL (VHL:VHL ligand --- CTNNB1:xStAx)	-
28920	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Burslem GM (2020)	32519703	223655	8553	Bivalent ligand 155	GMB-805|Bivalent_ligand_155	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: GMB-805 (VHL:VHL1 --- BCR-ABL:ABL001)	-
28931	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ward CC (2019)	31059647	220118	8477	Bivalent ligand 160	CCW 28-3|Bivalent_ligand_160	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111974	6047	RES4-26	RNF4	SLX5|SNURF	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CCW 28-3 (RNF4:CCW 16 --- BRD4:JQ1)	-
28933	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Spradlin JN (2019)	31209351	220371	8478	Bivalent ligand 161	XH2|Bivalent_ligand_161	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: XH2 (RNF114:nimbolide --- BRD4:JQ1)	-
28937	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK4:palbociclib)	-
28939	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8476	Bivalent ligand 163	BSJ-02-162|Bivalent_ligand_163	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ02162 (CRBN:thalidomide --- CDK6:palbociclib)	-
28941	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK4:ribociclib)	-
28943	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8481	Bivalent ligand 164	BSJ-01-152|Bivalent_ligand_164	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01152 (CRBN:thalidomide --- CDK6:ribociclib)	-
28945	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK4:abemaciclib)	-
28947	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK6:abemaciclib)	-
28951	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8479	Bivalent ligand 166	BSJ-01-187|Bivalent_ligand_166	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01187 (CRBN:thalidomide --- CDK4:ribociclib)	-
28953	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8480	Bivalent ligand 167	YKL-06-102|Bivalent_ligand_167	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL06102 (CRBN:thalidomide --- CDK6:palbociclib)	-
28967	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK4:palbociclib)	-
28969	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8473	Bivalent ligand 168	BSJ-03-204|Bivalent_ligand_168	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK6:palbociclib)	-
28971	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8474	Bivalent ligand 169	BSJ-04-132|Bivalent_ligand_169	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ04132 (CRBN:thalidomide --- CDK4:ribociclib)	-
28973	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8472	Bivalent ligand 170	BSJ-03-123|Bivalent_ligand_170	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ03123 (CRBN:thalidomide --- CDK6:palbociclib)	-
28974	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	target	Standardized BVL Name: peptide 5 (BIRC2:MV1 --- NOTCH1:CSL)	-
28976	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	target	Standardized BVL Name: peptide 5 (BIRC3:MV1 --- NOTCH1:CSL)	-
28979	110913	4851	-	NOTCH1	AOS5|AOVD1|TAN1|hN1	9606	Homo sapiens	degradation	target	Ohoka N (2017)	29050782	208402	8471	Bivalent ligand 171	peptide 5|Bivalent_ligand_171	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: peptide 5 (XIAP1:MV1 --- NOTCH1:CSL)	-
29124	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Zhang Y (2015)	26191364	212887	9192	(8S,11S,14S,17S,28S,31S,34S,37R)-37-(Cyclopropylsulfonylamino)-10,30-bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,34-bis(naphthalen-2-ylmethyl)-12,15,32,35-tetraoxo-2,23-dioxa-5,6,7,10,13,16,30,33,36-nonazahexacyclo[37.2.2.219,22.14,7.18,11.128,31]octatetraconta-1(42),4(48),5,19,21,39(43),40,45-octaene-17-carboxylic acid	BDBM50112346	-	PUBCHEM	122187534	C83H106N14O14S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MLQVQPMTZJBGEY-VGEDNRJQSA-N
29152	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9217	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078360	-	PUBCHEM	71582189	C80H96N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RPYLESOPIPCLOC-IJLYYPGQSA-N
29153	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9218	(2S,5S,8S,11S,17S,20S,23S,26S)-4,19-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-8,23-bis(naphthalen-2-ylmethyl)-6,9,21,24-tetraoxo-1,4,7,10,14,15,16,19,22,25,29,30-dodecazapentacyclo[26.2.1.12,5.113,16.117,20]tetratriaconta-13(33),14,28(31),29-tetraene-11,26-dicarboxylic acid	BDBM50078359	-	PUBCHEM	71582339	C64H80N16O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCYVAJKIAWNFPS-WBVBMDTLSA-N
29154	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9219	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078354	-	PUBCHEM	89569624	C84H100N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HZGOIKMHTUCXAI-KWEJKZBISA-N
29155	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9217	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078360	-	PUBCHEM	71582189	C80H96N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RPYLESOPIPCLOC-IJLYYPGQSA-N
29156	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9218	(2S,5S,8S,11S,17S,20S,23S,26S)-4,19-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-8,23-bis(naphthalen-2-ylmethyl)-6,9,21,24-tetraoxo-1,4,7,10,14,15,16,19,22,25,29,30-dodecazapentacyclo[26.2.1.12,5.113,16.117,20]tetratriaconta-13(33),14,28(31),29-tetraene-11,26-dicarboxylic acid	BDBM50078359	-	PUBCHEM	71582339	C64H80N16O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCYVAJKIAWNFPS-WBVBMDTLSA-N
29157	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9220	(10S,13S,16S,19S,33S,36S,39S,42S)-16,39-Dibenzyl-12,35-bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3,14,17,26,37,40-hexaoxo-2,7,8,9,12,15,18,25,30,31,32,35,38,41-tetradecazaheptacyclo[42.2.2.221,24.16,9.110,13.129,32.133,36]tetrapentaconta-1(47),6(54),7,21,23,29(50),30,44(48),45,51-decaene-19,42-dicarboxylic acid	BDBM50078358	-	PUBCHEM	71581702	C74H94N18O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LKZUGDULMRPQJR-PZOHCTHGSA-N
29158	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9221	(8S,11S,14S,17S,29S,32S,35S,38S)-14,35-Dibenzyl-10,31-bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078357	-	PUBCHEM	71581703	C70H88N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VLPFNQKFYWKXGS-JCDMWVPISA-N
29159	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9222	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-1-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078356	-	PUBCHEM	118732795	C78H92N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BUUIRUGUZNCDSQ-KCUAZDICSA-N
29160	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9223	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-3-methyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078355	-	PUBCHEM	71581838	C78H92N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JSGZGDDJOKLCEY-PFFMIVSTSA-N
29161	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	unknown	target	Seigal BA (2015)	25695766	224774	9219	(8S,11S,14S,17S,29S,32S,35S,38S)-10,31-Bis[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-14,35-bis(naphthalen-2-ylmethyl)-12,15,33,36-tetraoxo-2,23-dioxa-5,6,7,10,13,16,26,27,28,31,34,37-dodecazaheptacyclo[38.2.2.219,22.14,7.18,11.125,28.129,32]pentaconta-1(43),4(50),5,19,21,25(46),26,40(44),41,47-decaene-17,38-dicarboxylic acid	BDBM50078354	-	PUBCHEM	89569624	C84H100N16O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HZGOIKMHTUCXAI-KWEJKZBISA-N
29174	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9234	4-N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030280	-	PUBCHEM	73506219	C63H82N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAKVXIUNQHYAPX-UPKUDDMJSA-N
29175	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9235	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methoxy]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030278	-	PUBCHEM	90089727	C63H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PXWQVOUQYPMEME-NMZKVUILSA-N
29176	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9236	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethynyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030275	-	PUBCHEM	90089572	C64H81N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MZOKCLGAIIRHDG-KHFWCYFCSA-N
29177	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9237	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[2-[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]ethyl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030273	-	PUBCHEM	90089737	C64H85N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MRQUIOMXZIGPPW-KHFWCYFCSA-N
29178	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9238	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-benzothiazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030272	-	PUBCHEM	118497975	C64H81N11O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SYZOGRWMVSXFBX-OVCCXHLHSA-N
29179	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9239	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[5-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]-1,3-oxazol-2-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	BDBM50030270	-	PUBCHEM	73507318	C60H79N11O9	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VYZMHQWZWYAOIA-QLYDQGARSA-N
29180	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9240	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030269	-	PUBCHEM	118323269	C63H83N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LDVMHSURAWAEBW-YUTDAYPPSA-N
29181	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9241	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-1-(2-fluorophenyl)ethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030268	-	PUBCHEM	73603510	C61H80FN9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SUVGZSPIXFUCLS-NQFXVQPCSA-N
29182	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9242	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1R)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030266	-	PUBCHEM	73603641	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-DFNGJWONSA-N
29183	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Kim KS (2014)	25278234	212888	9243	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-N-[[4-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoyl]phenyl]methyl]-N-[(1S)-2-methoxy-1-phenylethyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50030265	-	PUBCHEM	118715865	C62H83N9O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XZWQAFLMOTZHHO-UICOXBBFSA-N
29199	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2014)	25261927	224778	9249	N-[4-[3-Chloro-4-[(3S)-oxolan-3-yl]oxyanilino]thieno[2,3-d]pyrimidin-6-yl]-N'-hydroxyoctanediamide	BDBM50102566	-	PUBCHEM	118715746	C24H28ClN5O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DHVTZWIWZWPIFU-INIZCTEOSA-N
29200	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2014)	25261927	224778	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29201	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2014)	25233084	224779	9250	8-Mercapto-octanoic acid phenylamide	8-MERCAPTO-OCTANOIC ACID PHENYLAMIDE|ZINC13609343|N-PHENYL-8-SULFANYLOCTANAMIDE|8-MERCAPTO-N-PHENYLOCTANAMIDE|BDBM50027601	-	PUBCHEM	11149404	C14H21NOS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VTVJPXWTXILBGK-UHFFFAOYSA-N
29202	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2014)	25233084	224779	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29231	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9277	(2S)-N-[(1S)-2-[(3Ar,7aS)-6-(2-phenylethyl)-3,3a,4,5,7,7a-hexahydro-2H-pyrrolo[2,3-c]pyridin-1-yl]-1-cyclohexyl-2-oxoethyl]-2-(methylamino)propanamide	CS-0006862|LBW242|867324-12-7|HY-15519|(2S)-N-[(1S)-2-[(3AR,7AS)-6-(2-PHENYLETHYL)-3,3A,4,5,7,7A-HEXAHYDRO-2H-PYRROLO[2,3-C]PYRIDIN-1-YL]-1-CYCLOHEXYL-2-OXOETHYL]-2-(METHYLAMINO)PROPANAMIDE|BDBM50364485	-	PUBCHEM	11503417	C27H42N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HCSMRSHIIKPNAK-LSAVBLLPSA-N
29232	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9278	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(2-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001139	-	PUBCHEM	90654412	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VUHJRMSITOPODU-JELQSWKKSA-N
29233	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9279	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Hydroxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001138	-	PUBCHEM	90654411	C24H36N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNEFKNCSOQRMCU-CRDRRFEFSA-N
29234	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9280	(2S)-N-[(2S,7R,9S,13S)-4-[2-(3-Methoxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001136	-	PUBCHEM	90654409	C25H38N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PTCUWTLAVOGZOF-YFVPBJFGSA-N
29235	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9281	(2S)-N-[(2S,7R,9S,13S)-4-[2-(2-Methoxyphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001135	-	PUBCHEM	90654408	C25H38N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NDQMUJBKPCHPFP-WFMNFSIZSA-N
29236	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9282	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Fluorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001134	-	PUBCHEM	90654407	C24H35FN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NPUNAPHKJPGXNY-ORDMVQLLSA-N
29237	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9283	(2S)-N-[(2S,7R,9S,13S)-4-[2-(2-Fluorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001133	-	PUBCHEM	90654406	C24H35FN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HPONQTAHVJCUCR-CRDRRFEFSA-N
29238	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9284	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Bromophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001132	-	PUBCHEM	90654405	C24H35BrN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BCFKWSBDCRMWRK-ORDMVQLLSA-N
29239	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9285	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-(2-phenylethyl)-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001131	-	PUBCHEM	90654404	C24H36N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LTFVDAMNPLQBHE-WFMNFSIZSA-N
29240	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9286	(6S,9Ar)-2,2-dimethyl-6-[[(2S)-2-(methylamino)propanoyl]amino]-N-(5-methyl-2-phenylpyrazol-3-yl)-5-oxo-3,6,7,8,9,9a-hexahydro-[1,3]thiazolo[3,2-a]azepine-3-carboxamide	BDBM50001130	-	PUBCHEM	90654403	C25H34N6O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RBLGKKZTMVKMNE-CPCSJTIGSA-N
29241	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9287	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-[6-[2-[(2S,7R,9S,13S)-13-[[(2S)-2-(methylamino)propanoyl]amino]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-4-yl]-2-oxo-1-phenylethoxy]hexa-2,4-diynoxy]-2-phenylacetyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001129	-	PUBCHEM	86276147	C54H70N8O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CNHIJRXXUZNFIO-TXLCXPLDSA-N
29242	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9288	Phenyl (2S,7R,9S,13S)-13-[[(2S)-2-(methylamino)propanoyl]amino]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecane-4-carboxylate	BDBM50001125	-	PUBCHEM	90654399	C23H32N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	COOWRGHTGIMRRI-SQIBXOBRSA-N
29243	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9289	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-(2-phenylacetyl)-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001101	-	PUBCHEM	90654394	C24H34N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RMWMSAOQRVQSSL-DARKYYSBSA-N
29244	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9290	(2S)-N-[(2S,7R,9S,13S)-4-[2-(1H-Indol-3-yl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001083	-	PUBCHEM	90654382	C26H37N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NXKKLSUXQLAFFE-SOFANIRLSA-N
29245	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9291	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-14-oxo-4-[2-[4-(trifluoromethyl)phenyl]ethyl]-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001081	-	PUBCHEM	90654380	C25H35F3N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CBUKBSAVVSVBEX-ORDMVQLLSA-N
29246	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9292	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(4-nitrophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001080	-	PUBCHEM	90654379	C24H35N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AQTFKDCKLOSLNK-ORDMVQLLSA-N
29247	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9293	(2S)-N-[(2S,7R,9S,13S)-4-[2-(3,4-Dichlorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001079	-	PUBCHEM	90654378	C24H34Cl2N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FAPNSKGNSXRVLR-CBJPPDNLSA-N
29248	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9294	(2S)-N-[(2S,7R,9S,13S)-4-[2-(4-Chlorophenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]-2-(methylamino)propanamide	BDBM50001078	-	PUBCHEM	90654377	C24H35ClN4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DOFKWVQMIJUKCV-ORDMVQLLSA-N
29249	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9295	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(4-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001077	-	PUBCHEM	90654376	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AQFHGNZPIGAZGV-JELQSWKKSA-N
29250	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Hird AW (2014)	24631189	224785	9296	(2S)-2-(Methylamino)-N-[(2S,7R,9S,13S)-4-[2-(3-methylphenyl)ethyl]-14-oxo-1,4-diazatricyclo[7.5.0.02,7]tetradecan-13-yl]propanamide	BDBM50001076	-	PUBCHEM	90654375	C25H38N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AVBZMSWFBFFJGJ-JELQSWKKSA-N
29308	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nalawansha DA (2017)	27977115	224801	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29309	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nalawansha DA (2017)	27977115	224801	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29310	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Miyake Y (2016)	27454931	224802	9324	(2E,4S,5E)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,5-dienamide	S-TSA|BDBM197337	-	PUBCHEM	122198566	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ALCVRKZFLFWUAZ-CSFUQHBASA-N
29311	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Miyake Y (2016)	27454931	224802	9325	(2E,4R,5E)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,5-dienamide	R-TSA|BDBM197336	-	PUBCHEM	122198565	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ALCVRKZFLFWUAZ-LSSUCPAZSA-N
29312	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li J (2016)	27235003	224803	4802	Belinostat	UNII-F4H96P17NZ|NSC-726630|ZINC3818726|ABP000140|866323-14-0|SC-71101|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|SW219445-1|NSC726630|BELEODAQ|BCPP000351|EX-A180|PX 105684|QCR-181|BCP01741|BRD-K17743125-001-01-9|GTPL7496|(E)-N-HYDROXY-3-(3-(N-PHENYLSULFAMOYL)PHENYL)ACRYLAMIDE|BELINOSTAT - PXD101|SB16466|CC-489|AOB87787|BELINOSTAT|AX8144528|MLS006011091|AC-25046|AB0007889|BELINOSTAT (PXD101)|BELINOSTAT,PXD101, PX105684|W-5363|(E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|414864-00-9|D08870|(E)-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENEHYDROXAMIC ACID|BELINOSTAT [USAN:INN]|SMR004702879|Q4882925|E-BELINOSTAT|BELINOSTAT (PXD101)|PXD101|PXD 101|N-HYDROXY-3-(3-PHENYLSULPHAMOYLPHENYL)ACRYLAMIDE|API0003555|BELINOSTAT (USAN/INN)|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]ACRYLAMIDE|BELEODAQ (TN)|PUBCHEM22405|NCGC00263155-05|(E)-N-HYDROXY-3-(3-PHENYLSULFAMOYL-PHENYL)-ACRYLAMIDE|PXD-101|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PR|S1085|LS41098|PX-105684|BELINOSTAT PH3|N-HYDROXY-3-(3-PHENYLSULFAMOYLPHENYL)ACRYLAMIDE|EC-000.2286|BELINOSTAT/PXD101,PX105684/|5OG|DTXSID60194378|2-PROPENAMIDE, N-HYDROXY-3-(3-((PHENYLAMINO)SULFONYL)PHENYL)-, (2E)-|BCP9000386|PX105684|F4H96P17NZ|N-HYDROXY-3-[(PHENYLAMINO)SULFONYL]-TRANS-CINNAMAMIDE|AS-17068|BELINOSTAT(RANDOM CONFIGURATION)|A25012|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE|AKOS025401741|N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE|CCG-208758|2-PROPENAMIDE, N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-, (2E)-|DB05015|J-523584|BDBM25150	beleodaq	DRUGBANK	DB05015	C15H14N2O4S	small molecule	L01XX49	866323-14-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NCNRHFGMJRPRSK-MDZDMXLPSA-N
29313	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li J (2016)	27235003	224803	9326	(E)-N-Hydroxy-3-[3-[[(1S)-2-(naphthalen-1-ylamino)-2-oxo-1-phenylethyl]sulfamoyl]phenyl]prop-2-enamide	(S,E)-N-HYDROXY-3-(3-(N-(2-(NAPHTHALEN-1-YLAMINO)-2-OXO-1-PHENYLETHYL)SULFAMOYL)PHENYL)ACRYLAMIDE (10S)|BDBM198192	-	PUBCHEM	122198640	C27H23N3O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JCEFNCFZXQDHRY-ZOGILVBSSA-N
29319	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29320	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	9332	N-Hydroxy-4-[2-[(E)-2-phenylethenyl]-1,3-thiazol-4-yl]butanamide	ONC(CCCC=1N=C(SC=1)\C=C\C1=CC=CC=C1)=O|BDBM50156678	-	PUBCHEM	102514716	C15H16N2O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HJPIJALRLZVGMS-MDZDMXLPSA-N
29321	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yoo J (2016)	27060764	224805	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29339	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9345	5-Benzyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151283	-	PUBCHEM	126582837	C20H18F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JJZFDILZILDRTQ-UHFFFAOYSA-N
29340	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9346	5-Cyclopropyl-2-(5-methyl-1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151282	-	PUBCHEM	126582839	C17H18F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GJSCCYDUKNGSLB-UHFFFAOYSA-N
29341	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9347	5-Cyclopropyl-2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151281	-	PUBCHEM	126582843	C20H22F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZUPRHDPCDWVJDA-UHFFFAOYSA-N
29342	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9348	5-(2-Methylpropyl)-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151280	-	PUBCHEM	126582841	C17H20F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AZLBBFOVLFWKTC-UHFFFAOYSA-N
29343	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9349	5-Cyclopropyl-2-(1,3-thiazol-2-yl)-N-(5,5,5-trifluoro-4-oxopentyl)-1,3-thiazole-4-carboxamide	BDBM50151278	-	PUBCHEM	126582908	C15H14F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVCSQKKFUYQSGT-UHFFFAOYSA-N
29344	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9350	5-Cyclopropyl-2-(1,3-thiazol-2-yl)-N-(6,6,6-trifluoro-5-oxohexyl)-1,3-thiazole-4-carboxamide	BDBM50151277	-	PUBCHEM	91938063	C16H16F3N3O2S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OHRUWOKDVPCLPC-UHFFFAOYSA-N
29345	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Gong CJ (2016)	26890114	224811	9351	5-Cyclopropyl-N-[5-(hydroxyamino)-5-oxopentyl]-2-(1,3-thiazol-2-yl)-1,3-thiazole-4-carboxamide	BDBM50020897	-	PUBCHEM	71468161	C15H18N4O3S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MVJAEZIEZVJAFM-UHFFFAOYSA-N
29346	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9352	3-Pyrazin-2-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144216	-	PUBCHEM	127028943	C14H19N5OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GYWQCXUVPDWXRB-UHFFFAOYSA-N
29347	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9353	3-(1H-Indol-3-yl)-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144214	-	PUBCHEM	137174935	C18H22N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QTJRTUWSBZMZMT-UHFFFAOYSA-N
29348	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9354	N-(6-Sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144212	-	PUBCHEM	127026695	C10H17N3OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OJQALHBLSWWPHJ-UHFFFAOYSA-N
29349	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9355	3-Phenyl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144210	-	PUBCHEM	127027677	C16H21N3OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZTCVPCNBUBKBA-UHFFFAOYSA-N
29350	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9356	3-(3,4-Dimethoxyphenyl)-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50144209	-	PUBCHEM	127027679	C18H25N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KATIKUFCGSOWFA-UHFFFAOYSA-N
29351	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9357	N-(6-Sulfanylhexyl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole-5-carboxamide	BDBM50144208	-	PUBCHEM	127027680	C19H27N3O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HIUNIEQHYXYXSL-UHFFFAOYSA-N
29352	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9358	3-Pyridin-4-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143997	-	PUBCHEM	127027995	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KYZMEJZVXICXQX-UHFFFAOYSA-N
29353	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9359	3-Pyridin-3-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143996	-	PUBCHEM	127025178	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UMHAIDYPJKYSES-UHFFFAOYSA-N
29354	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9360	3-Pyridin-2-yl-N-(6-sulfanylhexyl)-1H-pyrazole-5-carboxamide	BDBM50143995	-	PUBCHEM	127028973	C15H20N4OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VRGLHLDCWONREK-UHFFFAOYSA-N
29355	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29356	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26814680	224812	9361	7-Mercapto-heptanoic acid phenylamide	ZINC13609304|7-MERCAPTO-HEPTANOIC ACID PHENYLAMIDE|N-PHENYL-7-SULFANYLHEPTANAMIDE|THIOL-SAHA (T-SAHA)|BDBM152692	-	PUBCHEM	11379392	C13H19NOS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CFKBMXXDXYFDET-UHFFFAOYSA-N
29357	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ghosh B (2016)	26804233	224813	9362	N'-Hydroxy-N-[(E)-(4-pyridin-3-ylphenyl)methylideneamino]heptanediamide	BRD-K51966546-001-02-2|BDBM50143887	-	PUBCHEM	73707550	C19H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SOSXJHXYTVYMTE-FYJGNVAPSA-N
29358	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ghosh B (2016)	26804233	224813	9363	N'-Hydroxy-N-[(E)-(4-phenylphenyl)methylideneamino]heptanediamide	J3.581.861H|7-OXO-7-[2-[(Z)-(BIPHENYL-4-YL)METHYLENE]HYDRAZINO]HEPTANEHYDROXAMIC ACID|BRD-K35010406-001-01-1|BDBM50143884	-	PUBCHEM	25118059	C20H23N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AEIVDBATQVVQFS-RCCKNPSSSA-N
29359	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Peng FW (2016)	26741358	224814	9364	7-[4-(4-Bromoanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide	BDBM50142796	-	PUBCHEM	127028030	C22H25BrN4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BNWIAUUKBJSRSZ-UHFFFAOYSA-N
29370	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9374	4-[3-(4-Fluorophenyl)-5-(6-sulfanylhexylcarbamoyl)pyrazol-1-yl]butanoic acid	BDBM50143530	-	PUBCHEM	127026737	C20H26FN3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GUKWYUINVSHUKE-UHFFFAOYSA-N
29371	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9375	2-[3-(4-Fluorophenyl)-5-(6-sulfanylhexylcarbamoyl)pyrazol-1-yl]acetic acid	BDBM50143508	-	PUBCHEM	127026735	C18H22FN3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KDSZJUGHUQDOGC-UHFFFAOYSA-N
29372	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	9376	(1R,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone	ROMIDEPSIN (FK228, DEPSIPEPTIDE)|ZINC136702520|128517-07-7|BDBM50048864	-	PUBCHEM	11947684	C24H36N4O6S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OHRURASPPZQGQM-QSVHVVLASA-N
29373	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wen J (2016)	26706171	224819	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29374	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9377	4-[(E)-N-[[4-(Dimethylamino)benzoyl]-methylamino]-C-methylcarbonimidoyl]-N-hydroxybenzamide	BDBM50146080	-	PUBCHEM	127025647	C19H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JCTMSWPCFNKFGT-DEDYPNTBSA-N
29375	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9378	4-[(E)-N-[[4-(Dimethylamino)benzoyl]amino]-C-methylcarbonimidoyl]-N-hydroxybenzamide	BDBM50146079	-	PUBCHEM	122601076	C18H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YBJMRJLHXVKOOB-XDHOZWIPSA-N
29376	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9379	4-[(E)-[[4-(Dimethylamino)benzoyl]-methylhydrazinylidene]methyl]-N-hydroxybenzamide	BDBM50146077	-	PUBCHEM	127025646	C18H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOJNZHSNJLHVML-XDHOZWIPSA-N
29377	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	9380	4-[(E)-[[4-(Dimethylamino)benzoyl]hydrazinylidene]methyl]-N-hydroxybenzamide	BDBM50146076	-	PUBCHEM	122601008	C17H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HHDICTUTXIOTBC-WOJGMQOQSA-N
29378	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Rodrigues DA (2016)	26705137	224820	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29379	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9381	4-[(2S)-1-[5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-(2-phenylethyl)benzimidazol-1-yl]propan-2-yl]morpholine	BDBM50151662	-	PUBCHEM	127031779	C27H32N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SAMCWHOXZPKYQG-IBGZPJMESA-N
29380	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9382	[[(3R)-4-[[3-[2-[2-[[(5S)-5-Acetamido-6-amino-6-oxohexyl]amino]-2-oxoethyl]sulfanylethylamino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl hydrogen phosphate	AC-LYS(COA)-NH2|BDBM50255529	-	PUBCHEM	44571034	C31H53N10O19P3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YGZKIOPJGFQDSR-QGSWMBNESA-N
29381	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9383	(2S)-2-[2-[[(1S)-1-Carboxy-3-[5-[(Z)-[(5S)-5-[3-(diaminomethylideneamino)propyl]-3,6-dioxopiperazin-2-ylidene]methyl]-2-hydroxyphenoxy]propyl]amino]-2-oxoethyl]-2-hydroxybutanedioic acid	BDBM50151656	-	PUBCHEM	127033885	C25H32N6O12	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GRAFKVRBLJRCBH-NCBISDQCSA-N
29382	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9384	(2S)-2-[[(3S)-3-Carboxy-5-[[(1S)-1-carboxy-3-[5-[(Z)-[(5S)-5-[3-(diaminomethylideneamino)propyl]-3,6-dioxopiperazin-2-ylidene]methyl]-2-hydroxyphenoxy]propyl]amino]-3-hydroxy-5-oxopentanoyl]amino]butanedioic acid	NK-13650A|BDBM50151655	-	PUBCHEM	71481176	C29H37N7O15	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CVSHHZDMYAPZPV-DFYJTYCZSA-N
29383	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Simon RP (2016)	26701186	224821	9385	Tert-butyl N-[5-[[2-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]acetyl]amino]pentyl]carbamate	BDBM50151651	-	PUBCHEM	50899265	C33H58N9O19P3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XQXLJFXFNXYRML-HSJNEKGZSA-N
29384	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kachhadia V (2016)	26689485	224822	9386	(E)-3-[4-[(E)-3-(Cyclopropylamino)-2-(4-fluorophenyl)prop-1-enyl]phenyl]-N-hydroxyprop-2-enamide	BDBM50143215	-	PUBCHEM	25269097	C21H21FN2O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NODIYCZWVUUEMT-HTZRGULJSA-N
29385	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kachhadia V (2016)	26689485	224822	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29386	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29387	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29388	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Reddy DN (2016)	26681404	224823	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29389	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29390	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9387	N-Hydroxy-2-naphthalen-2-yl-1,3-oxazole-4-carboxamide	BDBM50148620	-	PUBCHEM	127027175	C14H10N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SAZKVZYUJRPYFI-UHFFFAOYSA-N
29391	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9388	2-(4-Chlorophenyl)-N-hydroxy-1,3-oxazole-4-carboxamide	BDBM50148617	-	PUBCHEM	127025656	C10H7ClN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KHHYTDYDQPEPGS-UHFFFAOYSA-N
29392	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9389	N-Hydroxy-2-(4-phenylphenyl)-1,3-oxazole-4-carboxamide	BDBM50148613	-	PUBCHEM	127028391	C16H12N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TXHNXBSXQZDEJE-UHFFFAOYSA-N
29393	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	9390	2-(4-Bromophenyl)-N-hydroxy-1,3-oxazole-4-carboxamide	N-HYDROXY-2-(4-BROMOPHENYL)OXAZOLE-4-CARBOXAMIDE|P7V|J3.601.433D|2-(4-BROMOPHENYL)-N-HYDROXY-1,3-OXAZOLE-4-CARBOXAMIDE|BDBM50148612	-	PUBCHEM	127027171	C10H7BrN2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KHPRTOQUGAUDCM-UHFFFAOYSA-N
29394	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Senger J (2016)	26653328	224824	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29395	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Thaler F (2016)	26629860	224825	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29396	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Romero FA (2016)	26572217	224826	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29397	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Ni M (2015)	26481659	224827	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29398	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Peng FW (2015)	26475519	224828	9392	6-[4-(2,4-Dichloroanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyhexanamide	BDBM50132484	-	PUBCHEM	122195536	C21H22Cl2N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HQVSMMXKDYANJJ-UHFFFAOYSA-N
29399	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9393	Ricolinostat	SW219836-1|ZINC89630354|W-5979|AS-73344|D10661|ROCILINOSTAT (ACY-1215)|GTPL7010|ROCILINOSTAT|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]PYRIMIDINE-5-CARBOXAMIDE|ACY-63|DTXSID40157148|RICOLINOSTAT (USAN/INN)|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)-|CCG-269054|AK151416|7-{[2-(DIPHENYLAMINO)PYRIMIDIN-5-YL]FORMAMIDO}-N-HYDROXYHEPTANAMIDE|SMR004702950|EX-A139|UNII-WKT909C62B|ACN-030031|S8001|AH4|CS-0965|DB12376|Q27088553|NS00073045|ACY-1215|1316214-52-4|SB17054|CC-661|HMS3426C09|US8609678, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE [26]|AB0032517|BCP06028|A11940|X5832|AC-30258|2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE|MLS006011181|N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-2-(N-PHENYLANILINO)PYRIMIDINE-5-CARBOXAMIDE|HY-16026|WKT909C62B|NCGC00345802-05|J-690127|ACY1215|AX8288032|AKOS024259260|RICOLINOSTAT (ACY-1215)|RICOLINOSTAT [USAN:INN]|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-5-PYRIMIDINECARBOXAMIDE|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-|NCGC00345802-01|RICOLINOSTAT|HMS3653F17|KS-00000SAV|BDBM50439674	-	PUBCHEM	53340666	C24H27N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGZYDVAGYRLSKP-UHFFFAOYSA-N
29400	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9394	N-Hydroxy-6-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151381	-	PUBCHEM	122550126	C22H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YHQAMQHTTOJBPC-UHFFFAOYSA-N
29401	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9395	N-Hydroxy-5-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]pentanamide	ONC(CCCCOC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151380	-	PUBCHEM	122550235	C21H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VINHTOOQEORVNT-UHFFFAOYSA-N
29402	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9396	N-Hydroxy-2-[4-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]acetamide	ONC(COC1=CC=C(C=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)=O|BDBM50151378	-	PUBCHEM	122550234	C18H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MPMPKDWQOVDGGV-UHFFFAOYSA-N
29403	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9397	N-Hydroxy-6-[2-methoxy-5-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=C(C=CC(=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)OC)=O|BDBM50151377	-	PUBCHEM	122550213	C23H28N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOLDSRJBCFTJIA-UHFFFAOYSA-N
29404	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9398	Hdac6-IN-1	HY-18947|CS-0014660|SKLB-23BB|S8743|N-HYDROXY-4-[2-METHOXY-5-[METHYL(2-METHYLQUINAZOLINE-4-YL)AMINO]PHENOXY]BUTANAMIDE|ONC(CCCOC1=C(C=CC(=C1)N(C1=NC(=NC2=CC=CC=C12)C)C)OC)=O|J3.553.794E|1815580-06-3|HDAC6-IN-1|BDBM50151375	-	PUBCHEM	122550211	C21H24N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FWXZZFONXWYSEF-UHFFFAOYSA-N
29405	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9399	N-Hydroxy-6-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]hexanamide	BDBM50151325	-	PUBCHEM	127031757	C21H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YUAKVYNOFMVTES-UHFFFAOYSA-N
29406	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9400	N-Hydroxy-5-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]pentanamide	BDBM50151324	-	PUBCHEM	127030500	C20H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZRIVRHBHISBBGJ-UHFFFAOYSA-N
29407	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9401	N-Hydroxy-4-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]butanamide	BDBM50150960	-	PUBCHEM	127031734	C19H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMJDOVVCXHTCNO-UHFFFAOYSA-N
29408	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9402	N-Hydroxy-2-[4-[methyl-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]phenoxy]acetamide	BDBM50150959	-	PUBCHEM	127031756	C17H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZDRSRLVZCRYVJO-UHFFFAOYSA-N
29409	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9403	N-Hydroxy-6-[4-[methyl(quinazolin-4-yl)amino]phenoxy]hexanamide	ONC(CCCCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150955	-	PUBCHEM	122550135	C21H24N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NXBDQDGEFPQVSI-UHFFFAOYSA-N
29410	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9404	N-Hydroxy-5-[4-[methyl(quinazolin-4-yl)amino]phenoxy]pentanamide	ONC(CCCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150954	-	PUBCHEM	122550134	C20H22N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TYGPIYZPTOOAMW-UHFFFAOYSA-N
29411	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9405	N-Hydroxy-4-[4-[methyl(quinazolin-4-yl)amino]phenoxy]butanamide	ONC(CCCOC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150953	-	PUBCHEM	122550129	C19H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGPSFMYVFDFUJS-UHFFFAOYSA-N
29412	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	9406	N-Hydroxy-2-[4-[methyl(quinazolin-4-yl)amino]phenoxy]acetamide	ONC(COC1=CC=C(C=C1)N(C1=NC=NC2=CC=CC=C12)C)=O|BDBM50150951	-	PUBCHEM	122550132	C17H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WKPDRDKNRMYFAG-UHFFFAOYSA-N
29413	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
29414	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang Z (2016)	26443078	224829	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29415	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Musso L (2015)	26376355	224830	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29419	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2015)	26331334	224832	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29420	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Muthyala R (2015)	26264503	224833	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29421	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Muthyala R (2015)	26264503	224833	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29422	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Chessari G (2015)	26218264	224834	9410	1-(6-Benzyl-3,3-dimethyl-2H-pyrrolo[3,2-c]pyridin-1-yl)-2-[(2R,5R)-2-(methoxymethyl)-5-methylpiperazin-1-yl]ethanone	1-(6-BENZYL-3,3-DIMETHYL-2H-PYRROLO[3,2-C]PYRIDIN-1-YL)-2-[(2R,5R)-2-(METHOXYMETHYL)-5-METHYLPIPERAZIN-1-YL]ETHANONE|US9018214, 63|1-(3,3-DIMETHYL-6-BENZYL-2,3-DIHYDRO-1H-PYRROLO[3,2-C]PYRIDINE-1-YL)-2-((3R,6R)-3-METHYL-6-METHOXYMETHYLPIPERAZINE-1-YL)ETHANONE|BDBM156012	-	PUBCHEM	70981017	C25H34N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XOZJVPQFZSCGTE-WIYYLYMNSA-N
29423	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9411	N-[1-(2-Chloro-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-CHLORO-4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109015	-	PUBCHEM	122184850	C24H27ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IJGUAWCQKOESOS-UHFFFAOYSA-N
29424	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9412	N-[1-(2-Bromo-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-BROMO-4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109014	-	PUBCHEM	122184851	C24H27BrN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QNXRAIMDOJFMKD-UHFFFAOYSA-N
29425	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9413	N'-Hydroxy-N-[1-(4-methylanilino)isoquinolin-7-yl]octanediamide	N-[1-[(4-METHYLPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109013	-	PUBCHEM	122184847	C24H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DHMRFGYKNXQOFG-UHFFFAOYSA-N
29426	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9414	N'-Hydroxy-N-[1-(naphthalen-2-ylamino)isoquinolin-7-yl]octanediamide	BDBM50109011	-	PUBCHEM	122184848	C27H28N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HUKJAHRJEYMMCE-UHFFFAOYSA-N
29427	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9415	N-[1-(4-Bromo-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUORO-4-BROMOPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109010	-	PUBCHEM	122184845	C23H24BrFN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DFKQAHYOXDWTAQ-UHFFFAOYSA-N
29428	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9416	(E)-N-Hydroxy-3-[4-[[[1-(4-methylanilino)isoquinolin-7-yl]amino]methyl]phenyl]prop-2-enamide	BDBM50109009	-	PUBCHEM	122185150	C26H24N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KPLJHTZFLSOICT-MDWZMJQESA-N
29429	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9417	N-[1-(3-Chloro-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUORO-3-CHLOROPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109008	-	PUBCHEM	122184846	C23H24ClFN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LYWPEQFLYUJPIU-UHFFFAOYSA-N
29430	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9418	N'-Hydroxy-N-(1-morpholin-4-ylisoquinolin-7-yl)octanediamide	BDBM50109006	-	PUBCHEM	122184854	C21H28N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DTLWMGPSWXSCIY-UHFFFAOYSA-N
29431	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9419	N'-Hydroxy-N-[1-(4-propan-2-ylpiperazin-1-yl)isoquinolin-7-yl]octanediamide	BDBM50109004	-	PUBCHEM	122184855	C24H35N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KUEFYQRLDVPNAG-UHFFFAOYSA-N
29432	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9420	N-[1-(2-Fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	N-[1-[(2-FLUOROPHENYL)AMINO]ISOQUINOLINE-7-YL]-N'-HYDROXYOCTANEDIAMIDE|BDBM50109002	-	PUBCHEM	122184852	C23H25FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AGZGHJKLKCIIAU-UHFFFAOYSA-N
29433	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9421	N-[2-[(2,4-Dimethoxyphenyl)methyl]-1-oxoisoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50109000	-	PUBCHEM	122185147	C26H31N3O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GIKBCAFOYUWQMO-UHFFFAOYSA-N
29434	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9422	N-[1-(2-Fluoro-4-methylanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50108999	-	PUBCHEM	122184849	C24H27FN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QLJIGRZNVRDVNW-UHFFFAOYSA-N
29435	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9423	N'-Hydroxy-N-[2-(3-methylbutyl)-1-oxoisoquinolin-7-yl]octanediamide	BDBM50108184	-	PUBCHEM	122185146	C22H31N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FSIYMAGFRRSGGY-UHFFFAOYSA-N
29436	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9424	N-[2-[2-(Diethylamino)ethyl]-1-oxoisoquinolin-7-yl]-N'-hydroxyoctanediamide	BDBM50108162	-	PUBCHEM	122184858	C23H34N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZAKBEXUJXNNGOJ-UHFFFAOYSA-N
29437	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9425	N-(2-Butyl-1-oxoisoquinolin-7-yl)-N'-hydroxyoctanediamide	BDBM50108142	-	PUBCHEM	122184857	C21H29N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CIMZZSMMMYOQJV-UHFFFAOYSA-N
29438	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	9426	N'-Hydroxy-N-[1-(3-methoxypropylamino)isoquinolin-7-yl]octanediamide	BDBM50108129	-	PUBCHEM	122184856	C21H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGLLPZGTTQFMEG-UHFFFAOYSA-N
29439	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yang W (2015)	26211462	224835	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29441	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29442	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29443	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Zhan P (2015)	26086931	224837	9391	Sgc-cbp30	Q27088793|GTPL7529|C28H33CLN4O3|4-[(2S)-1-[2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)BENZIMIDAZOL-1-YL]PROPAN-2-YL]MORPHOLINE|HY-15826|(S)-4-(1-(2-(3-CHLORO-4-METHOXYPHENETHYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PROPAN-2-YL)MORPHOLINE|S7256|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-1,3-BENZODIAZOLE|AOB4800|5-(3,5-DIMETHYLISOXAZOLE-4-YL)-2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-1-[(S)-2-MORPHOLINOPROPYL]-1H-BENZOIMIDAZOLE|EX-A2159|SGC-CBP30|CCG-269770|AKOS024458401|NCGC00351475-07|A13227|ZINC96170456|CS-2096|2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE|SW219645-1|2LO|AS-56079|SGC-CBP30, >=98% (HPLC)|2715AH|1613695-14-9|BDBM188519	-	PUBCHEM	72201027	C28H33ClN4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GEPYBHCJBORHCE-SFHVURJKSA-N
29444	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9428	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3-thia-7,14,17,21-tetrazatricyclo[14.3.1.12,5]henicosa-1(20),2(21),16,18-tetraene-6,9,13-trione	BDBM50098420	-	PUBCHEM	122181882	C23H30N4O4S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YSQNJKVHVWRCPW-FXHDEUNJSA-N
29445	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9429	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3-thia-7,14,20,21-tetrazatricyclo[14.3.1.12,5]henicosa-1(19),2(21),16(20),17-tetraene-6,9,13-trione	(4R)-4,2-[CARBONYLIMINO[(S)-2-OXO-1-ISOPROPYLETHYLENE]OXY[(S)-1-OXO-7-MERCAPTO-4-HEPTENE-3,1-DIYL]IMINOMETHYLENE(PYRIDINE-2,6-DIYL)]-4BETA-METHYL-4,5-DIHYDROTHIAZOLE|BDBM50098418	-	PUBCHEM	25257993	C23H30N4O4S2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	USYOVMNNRIHXJQ-BEIBECRVSA-N
29446	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Clausen DJ (2015)	26054247	224838	9430	(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione	(4R)-4,2'-[CARBONYLIMINO[(S)-1-OXO-3-METHYLBUTANE-2,1-DIYL]OXY[(S)-1-OXO-7-MERCAPTO-4-HEPTENE-3,1-DIYL]IMINOMETHYLENE]-4BETA-METHYL-4,5-DIHYDRO-2,4'-BITHIAZOLE|(2S,5S,17R)-2-ISOPROPYL-5-[(E)-4-MERCAPTO-1-BUTENYL]-17-METHYL-13,10:17,14-DIEPINITRILO-4-OXA-11,15-DITHIA-1,8-DIAZACYCLOOCTADECA-12-ENE-3,7,18-TRIONE|BDBM50098414	-	PUBCHEM	24938735	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-BNVDZZMOSA-N
29448	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	9432	Naphthalen-1-yl 6-[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate	BDBM50094760	-	PUBCHEM	122181047	C36H36N2O8S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PQXAOJPTBDMVNK-UHFFFAOYSA-N
29449	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	9433	8-[4-[6-(3-Hydroxyphenoxy)sulfonyl-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]anilino]-8-oxooctanoic acid	BDBM50094750	-	PUBCHEM	122180823	C32H33NO9S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HNLHZLHXGMYVNW-UHFFFAOYSA-N
29450	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang C (2015)	25993269	224840	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29452	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Daniel KB (2015)	25974739	224842	9434	N-Phenyl-N'-[(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methoxy]octanediamide	BDBM50089657	-	PUBCHEM	122177622	C24H30N2O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HXFDEOSGMWWMSA-UHFFFAOYSA-N
29453	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Daniel KB (2015)	25974739	224842	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29455	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Duan W (2015)	25906087	224844	9436	6-[[4-(Benzenesulfonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]oxy]-N-hydroxyhexanamide	BDBM50087853	-	PUBCHEM	118737455	C14H17N3O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AGDGTFUFKSHWRN-UHFFFAOYSA-N
29456	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Duan W (2015)	25906087	224844	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29457	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Di Pompo G (2015)	25905694	224845	9437	N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamide	MC1742|MC 1742|5-{[4-(BIPHENYL-4-YL)-6-OXO-1,6-DIHYDROPYRIMIDIN-2-YL]SULFANYL}-N-HYDROXYPENTANAMIDE|ZINC140782936|5-[[6-OXO-4-(4-PHENYLPHENYL)-1H-PYRIMIDIN-2-YL]SULFANYL]PENTANEHYDROXAMIC ACID|AKOS027470271|1776116-74-5|BDBM50087845	-	PUBCHEM	136173089	C21H21N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AOFVDNFTELWRHV-UHFFFAOYSA-N
29458	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Di Pompo G (2015)	25905694	224845	9438	N-[6-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]pyridin-3-yl]-2,3-diphenylpropanamide	J3.561.771J|MC-2625|BDBM50087841	-	PUBCHEM	118737400	C23H21N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UQSIPNLHOWORHA-BUHFOSPRSA-N
29459	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9439	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[6-(hydroxyamino)-6-oxohexyl]benzamide	BDBM50080071	-	PUBCHEM	136961657	C20H24N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LAPSXONRKCNPMH-UHFFFAOYSA-N
29460	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9440	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-hydroxybenzamide	BDBM50080008	-	PUBCHEM	136961654	C14H13N7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DUXRBKWTYAMJCH-UHFFFAOYSA-N
29461	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9441	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	BDBM50080007	-	PUBCHEM	136961658	C21H26N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FDKBZGYHEWRDAU-UHFFFAOYSA-N
29462	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9442	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[8-(hydroxyamino)-8-oxooctyl]benzamide	BDBM50080006	-	PUBCHEM	136961659	C22H28N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UMZXWCBRVCVILS-UHFFFAOYSA-N
29463	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Sodji QH (2015)	25899338	224846	9443	4-[(2-Amino-4-oxo-3H-pteridin-6-yl)methylamino]-N-[9-(hydroxyamino)-9-oxononyl]benzamide	BDBM50080005	-	PUBCHEM	136961660	C23H30N8O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QJGGEUHIPSSJGP-UHFFFAOYSA-N
29464	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	He S (2015)	25815139	224847	9444	N-Hydroxy-7-[3-[4-[[(7-hydroxy-21-methyl-14-oxo-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15(20),16,18-heptaen-17-yl)amino]methyl]phenyl]-1,2,4-oxadiazol-5-yl]heptanamide	BDBM50089085	-	PUBCHEM	122177957	C35H37N7O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FTVNKVXRXIRGTC-UHFFFAOYSA-N
29465	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	He S (2015)	25815139	224847	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29481	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9460	4-[[(3S)-1-(4-Chlorophenyl)-3-methyl-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	J3.522.188C|4-[[(3S)-1-(4-CHLOROPHENYL)-2-OXO-3-METHYLPYRROLIDINE-3-YL]AMINO]BENZHYDROXIMIC ACID|BDBM50078748	-	PUBCHEM	118733374	C18H18ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMBODOHYRWZQEW-SFHVURJKSA-N
29482	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9461	N-Hydroxy-4-[(3-methyl-2-oxo-1-quinolin-6-ylpyrrolidin-3-yl)amino]benzamide	N-HYDROXY-4-[(3-METHYL-2-OXO-1-QUINOLIN-6-YLPYRROLIDIN-3-YL)AMINO]BENZAMIDE|BDBM50078747	-	PUBCHEM	57524107	C21H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RSKIXUXUCRJFFV-UHFFFAOYSA-N
29483	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9462	4-[[1-(4-Chlorophenyl)-3-methyl-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(4-CHLOROPHENYL)-3-METHYL-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|1390618-15-1|BDBM50078695	-	PUBCHEM	57524021	C18H18ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JMBODOHYRWZQEW-UHFFFAOYSA-N
29484	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9463	4-[[1-(4-Cyanophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(4-CYANOPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078690	-	PUBCHEM	57524835	C18H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YOFSZHJBQOKORL-UHFFFAOYSA-N
29485	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9464	4-[[1-(3,4-Dichlorophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(3,4-DICHLOROPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078687	-	PUBCHEM	57524908	C17H15Cl2N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BVYKJJVMJBRGCE-UHFFFAOYSA-N
29486	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9465	4-[[1-(3-Chlorophenyl)-2-oxopyrrolidin-3-yl]amino]-N-hydroxybenzamide	4-[[1-(3-CHLOROPHENYL)-2-OXOPYRROLIDIN-3-YL]AMINO]-N-HYDROXYBENZAMIDE|BDBM50078680	-	PUBCHEM	57524666	C17H16ClN3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	TZTDSVDQFPJDKR-UHFFFAOYSA-N
29487	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9466	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	(R)-7BETA-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-2-CARBOHYDROXIMIC ACID|BDBM50027662	-	PUBCHEM	92045024	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-QGZVFWFLSA-N
29488	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29489	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lin X (2015)	25734520	224849	9467	N-Hydroxy-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-1,2,3,4-tetrahydroquinoline-6-carboxamide	US8716285, 53|BDBM120996	-	PUBCHEM	56933019	C19H18N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YWYZSTJJOZEEKF-UHFFFAOYSA-N
29495	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Milite C (2015)	25730130	224851	9473	1,3,5-Tribenzylpyrimidine-2,4,6(1H,3H,5H)-trione	1,3,5-TRIBENZYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE|ZINC1701219|CTK7H0853|NSC109117|NSC-109117|BDBM50081172	-	PUBCHEM	268735	C25H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SFFBIIMMBIRGKT-UHFFFAOYSA-N
29496	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	unknown	target	Milite C (2015)	25730130	224851	9474	5-Benzoyl-1,3-dibenzyl-1,3-diazinane-2,4,6-trione	BDBM50081171	-	PUBCHEM	118735269	C25H20N2O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ILBMLQVDTUJJKC-UHFFFAOYSA-N
29503	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9481	Birinapant	AS-17035|DB11782|D10417|SMR004702997|AKOS030526366|ZINC96941868|BIRINAPANT [USAN:INN]|TL-32711|TL32711|UNII-6O4Z07B57R|Q27075298|Z-3165|TL 32711|A12738|BIRINAPANT (USAN/INN)|(2S,2'S)-N,N'-[(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS{METHANEDIYL[(2R,4S)-4-HYDROXYPYRROLIDINE-2,1-DIYL][(2S)-1-OXOBUTANE-1,2-DIYL]}]BIS[2-(METHYLAMINO)PROPANAMIDE] (NON-PREFERRED NAME)|S7015|C42H56F2N8O6|ABP001107|(2S,2'S)-N,N'-((2S,2'S)-((3S,3'S,5R,5'R)-5,5'-((6,6'-DIFLUORO-1H,1'H-[2,2'-BIINDOLE]-3,3'-DIYL)BIS(METHYLENE))BIS(3-HYDROXYPYRROLIDINE-5,1-DIYL))BIS(1-OXOBUTANE-2,1-DIYL))BIS(2-(METHYLAMINO)PROPANAMIDE)|(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-FLUORO-2-[6-FLUORO-3-[[(2R,4S)-4-HYDROXY-1-[(2S)-2-[[(2S)-2-(METHYLAMINO)PROPANOYL]AMINO]BUTANOYL]PYRROLIDIN-2-YL]METHYL]-1H-INDOL-2-YL]-1H-INDOL-3-YL]METHYL]-4-HYDROXYPYRROLIDIN-1-YL]-1-OXOBUTAN-2-YL]-2-(METHYLAMINO)PROPANAM|HY-16591|CS-1719|2269AH|CCG-270498|(2S,2'S)-N,N'-[(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS{METHANEDIYL[(2R,4S)-4-HYDROXYPYRROLIDINE-2,1-DIYL][(2S)-1-OXOBUTANE-1,2-DIYL]}]BIS[2-(METHYLAMINO)PROPANAMIDE]|(2S,2'S)-N,N'-((2S,2'S)-1,1'-((3S,3'S,5R,5'R)-5,5'-(6,6'-DIFLUORO-1H,1'H-2,2'-BIINDOLE-3,3'-DIYL)BIS(METHYLENE)BIS(3-HYDROXYPYRROLIDINE-5,1-DIYL))BIS(1-OXOBUTANE-2,1-DIYL))BIS(2-(METHYLAMINO)PROPANAMIDE)|BIRINAPANT|EX-A258|SW220103-1|(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-FLUORO-2-[6-FLUORO-3-[[(2R,4S)-4-HYDROXY-1-[(2S)-2-[[(2S)-2-(METHYLAMINO)PROPANOYL]AMINO]BUTANOYL]PYRROLIDIN-2-YL]METHYL]-1H-INDOL-2-YL]-1H-INDOL-3-YL]METHYL]-4-HYDROXYPYRROLIDIN-1-YL]-1-OXOBUTAN-2-YL]-2-(METHYLAMINO)PROPANAMIDE|GTPL7432|PROPANAMIDE, N,N'-[(6,6'-DIFLUORO[2,2'-BI-1H-INDOLE]-3,3'-DIYL)BIS[METHYLENE[(2R,4S)-4-HYDROXY-2,1-PYRROLIDINEDIYL][(1S)-1-ETHYL-2-OXO-2,1-ETHANEDIYL]]]BIS[2-(METHYLAMINO)-, (2S,2'S)-|6O4Z07B57R|BIRINAPANT (TL32711)|DTXSID30155057|GT6|AOB87396|SC-93462|MLS006011237|SB16522|1260251-31-7|BDBM50071920	-	PUBCHEM	49836020	C42H56F2N8O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PKWRMUKBEYJEIX-DXXQBUJASA-N
29504	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9482	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]carbamoylamino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071863	-	PUBCHEM	73506880	C56H78N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HEUQZEJFJZTMAR-JSNDJGPMSA-N
29505	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9483	N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N'-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-2,2,3,3,4,4-hexafluoropentanediamide	BDBM50071851	-	PUBCHEM	90089551	C60H78F6N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QPEYDHPWFLBNLA-JSNDJGPMSA-N
29506	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9484	N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]pentanediamide	BDBM50071850	-	PUBCHEM	118497874	C60H84N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NQARVPNPYPHNOD-MLOMWMBNSA-N
29507	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9485	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[4-[2-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]ethyl]benzoyl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071849	-	PUBCHEM	118732584	C64H86N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	AWMDVTVHSSNVGB-KHFWCYFCSA-N
29508	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9486	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[(3R,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-7-((3R,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|BDBM50071848	-	PUBCHEM	72704974	C55H76N8O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MCUCXLXZRLIPIS-JSNDJGPMSA-N
29509	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9487	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]oxy-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071847	-	PUBCHEM	72704975	C55H76N8O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IBUAVNGTMFWXEN-JSNDJGPMSA-N
29510	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9488	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-7-(((3S,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)AMINO)-N-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|J3.503.491I|(3S)-2-(N-METHYL-L-ALA-3-METHYL-L-VAL-)-7-[[(2S,4S)-1-(N-METHYL-L-ALA-3-METHYL-L-VAL-)-2-[[(R)-TETRALIN-1-YL]CARBAMOYL]-4-PYRROLIDINYL]AMINO]-N-[(R)-TETRALIN-1-YL]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE|BDBM50071846	-	PUBCHEM	117710478	C55H77N9O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WBLPGUTUYUQRAH-JSNDJGPMSA-N
29511	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9489	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]-3-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3,7-dicarboxamide	(S)-2-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-N7-((3S,5S)-1-((S)-3,3-DIMETHYL-2-((S)-2-(METHYLAMINO)PROPANAMIDO)BUTANOYL)-5-(((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)CARBAMOYL)PYRROLIDIN-3-YL)-N3-((R)-1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3,7-DICARBOXAMIDE|BDBM50071845	-	PUBCHEM	72705162	C56H77N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UROIIFBMEHPIGR-JSNDJGPMSA-N
29512	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9490	(2S,4S)-1-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-4-N-[(3S)-2-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-2-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2,4-dicarboxamide	BDBM50071844	-	PUBCHEM	72705161	C56H77N9O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LVSCGNZQGKTFCG-NVLPYBLVSA-N
29513	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9491	(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-7-[[2-[[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]amino]-2-oxoethyl]amino]-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	BDBM50071843	-	PUBCHEM	73507094	C57H80N10O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GPKBDHHTTCGIAO-QLYDQGARSA-N
29514	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9492	N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]oxamide	BDBM50071821	-	PUBCHEM	73505798	C57H78N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NZLKULFMTUXYTR-JSNDJGPMSA-N
29515	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9493	1-N'-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]cyclobutane-1,1-dicarboxamide	BDBM50071820	-	PUBCHEM	73505797	C61H84N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OMVBPXMCVLZSMI-PRXWBPHPSA-N
29516	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	unknown	target	Perez HL (2015)	25584393	224853	9234	4-N-[(3S)-2-[(2S)-3,3-Dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-3-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]-3,4-dihydro-1H-isoquinolin-7-yl]-1-N-[(3S,5S)-1-[(2S)-3,3-dimethyl-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]-5-[[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-3-yl]benzene-1,4-dicarboxamide	BDBM50030280	-	PUBCHEM	73506219	C63H82N10O8	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MAKVXIUNQHYAPX-UPKUDDMJSA-N
29517	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9494	(2S)-N'-Hydroxy-2-[[(2S)-4-oxoazetidine-2-carbonyl]amino]-N-phenyloctanediamide	BDBM50042849	-	PUBCHEM	72947043	C18H24N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GHCWLYKERZOPPW-KBPBESRZSA-N
29518	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9495	(2S)-N'-Hydroxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-N-phenyloctanediamide	ST8086AA1|(2S)-N-[(1S)-7-(HYDROXYAMINO)-7-OXO-1-(PHENYLCARBAMOYL)HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|BDBM50042848	-	PUBCHEM	72946833	C19H26N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QMGDCUHFYVMSBA-GJZGRUSLSA-N
29519	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9496	(2S)-N'-Hydroxy-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]-N-[3-(trifluoromethyl)phenyl]octanediamide	ST-8078-AA1|(2R)-N-[(1S)-7-(HYDROXYAMINO)-7-OXO-1-[[3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL]HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|ST8078AA1|SB19290|1528755-83-0|BDBM50042847	-	PUBCHEM	72710871	C20H25F3N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XVGBJXUAVWXLJX-LSDHHAIUSA-N
29520	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9497	(2S)-N'-Hydroxy-N-(3-methylphenyl)-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]octanediamide	(2R)-N-[(1S)-7-(HYDROXYAMINO)-1-(M-TOLYLCARBAMOYL)-7-OXO-HEPTYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE|ST8074AA1|BDBM50042846	-	PUBCHEM	72947044	C20H28N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DAGWCJGDWGPDPA-JKSUJKDBSA-N
29521	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9498	(2R)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamide	BDBM50042845	-	PUBCHEM	91884636	C18H25N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YYSCXBPFYMVUDP-LSDHHAIUSA-N
29522	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	9499	(2R)-5-Oxo-N-[(2S)-1-oxo-7-sulfanyl-1-[3-(trifluoromethyl)anilino]heptan-2-yl]pyrrolidine-2-carboxamide	BDBM50027520	-	PUBCHEM	118719817	C19H24F3N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	CXRLQBYGPWEWJP-LSDHHAIUSA-N
29523	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Giannini G (2015)	25563890	224854	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29535	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	9511	N-[(2S)-1-[3-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]phenoxy]-3-(1H-indol-3-yl)propan-2-yl]-4-methoxybenzamide	BDBM50038747	-	PUBCHEM	118720522	C28H27N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UXMMCAXDMKCFRK-UNJYKCMZSA-N
29536	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	9512	N-[(2S)-1-[3-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]phenoxy]-3-(1H-indol-3-yl)propan-2-yl]-2-methoxybenzamide	BDBM50038729	-	PUBCHEM	118720529	C28H27N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VSRRZSNVPQPAFD-ARKBFRDHSA-N
29537	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2015)	25462271	224855	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29538	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Zwick V (2014)	25455492	224856	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29539	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9513	N-[[4-(Hydroxycarbamoyl)phenyl]methyl]-1-methylpyrrole-2-carboxamide	1454308-22-5|DB-096476|BDBM50440912	-	PUBCHEM	73333311	C14H15N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FOBBYTXDJVRRLB-UHFFFAOYSA-N
29540	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9514	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamide	ZINC68248700|N-HYDROXY-2-(1-METHYLPYRROLE-2-CARBONYL)-3,4-DIHYDRO-1H-ISOQUINOLINE-6-CARBOXAMIDE|EX-A1852|BCP29593|SYN1218|CS-0064770|N-HYDROXY-2-(1-METHYL-1H-PYRROLE-2-CARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBOXAMIDE|MPI 5A;MPI5A;HDAC6 INHIBITOR;HISTONE DEACETYLASE 6|1259296-46-2|MPI_5A|MPI-5A|DB-092801|HY-113957|1,2,3,4-TETRAHYDRO-N-HYDROXY-2-[(1-METHYL-1H-PYRROL-2-YL)CARBONYL]-6-ISOQUINOLINECARBOXAMIDE|BDBM50440907	-	PUBCHEM	49831258	C16H17N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NNQAQGDSGCGFER-UHFFFAOYSA-N
29541	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	8395	Tubastatin A	N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide|2XTSOX1NF8|Benzamide, N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-|Tubastatin A|N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide|BDBM50380399	-	CHEMSPIDER	28295021	C20H21N3O2	small molecule	-	1239262-52-2	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GOVYBPLHWIEHEJ-UHFFFAOYSA-N
29542	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9515	N-Hydroxy-7-(4-phenylbenzoyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide	N-HYDROXY-7-(4-PHENYLBENZOYL)-6,8-DIHYDRO-5H-IMIDAZO[1,2-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036305	-	PUBCHEM	53390842	C20H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OGQGBQMGXFYPBR-UHFFFAOYSA-N
29543	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9516	7-(1-Benzothiophene-2-carbonyl)-N-hydroxy-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide	7-(1-BENZOTHIOPHENE-2-CARBONYL)-N-HYDROXY-6,8-DIHYDRO-5H-IMIDAZO[1,2-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036304	-	PUBCHEM	58465842	C16H14N4O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GBJSJGWUCWJYTR-UHFFFAOYSA-N
29544	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9517	2-(4,5-Dichloro-1-methylpyrrole-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	2-(4,5-DICHLORO-1-METHYLPYRROLE-2-CARBONYL)-N-HYDROXY-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036303	-	PUBCHEM	58465719	C14H14Cl2N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GPVDZHZKWSWTAW-UHFFFAOYSA-N
29545	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9518	2-(1-Benzothiophene-2-carbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	BDBM50036301	-	PUBCHEM	118719410	C17H15N3O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PKOFMNJPOQAOMK-UHFFFAOYSA-N
29546	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9519	N-Hydroxy-2-(4-methoxybenzoyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(4-METHOXYBENZOYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036300	-	PUBCHEM	87400677	C16H17N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZBYDKMSHGGWYID-UHFFFAOYSA-N
29547	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9520	2-(Cyclohexanecarbonyl)-N-hydroxy-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	2-(CYCLOHEXANECARBONYL)-N-HYDROXY-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036299	-	PUBCHEM	58465664	C15H21N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IRYNPILZVVOIKV-UHFFFAOYSA-N
29548	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9521	N-Hydroxy-2-(1-methylindole-5-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(1-METHYLINDOLE-5-CARBONYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036296	-	PUBCHEM	58465755	C18H18N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZVYGMGIDIFWWGW-UHFFFAOYSA-N
29549	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9522	N-Hydroxy-2-(4-phenylbenzoyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(4-PHENYLBENZOYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036295	-	PUBCHEM	58465681	C21H19N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KWSAEIUYNAKOEW-UHFFFAOYSA-N
29550	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9523	N-Hydroxy-5-(1-methylindole-2-carbonyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-2-carboxamide	N-HYDROXY-5-(1-METHYLINDOLE-2-CARBONYL)-6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE-2-CARBOXAMIDE|BDBM50036291	-	PUBCHEM	58465705	C17H17N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ODOAGJBJOFXVAD-UHFFFAOYSA-N
29551	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9524	N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-7-carboxamide	N-HYDROXY-2-(1-METHYLPYRROLE-2-CARBONYL)-3,4-DIHYDRO-1H-PYRROLO[1,2-A]PYRAZINE-7-CARBOXAMIDE|BDBM50036285	-	PUBCHEM	58465708	C14H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HXYDFXUSMZJLIU-UHFFFAOYSA-N
29552	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	9525	Tubacin	AC-28328|DIOX-H_003551|Q27089032|AC1O7Y2P|TUBACIN (BML-GR362)|CTK8E6516|S2239|A10954|EX-A2172|1350555-93-9|HY-13428|CCG-270408|ZINC27551136|TUBACIN, >=98% (HPLC)|GTPL7374|537049-40-4|NCGC00346840-01|SW219084-1|BRD-K98426715-001-01-9|Y6280|N1-(4-((2R,4R,6S)-4-(((4,5-DIPHENYLOXAZOL-2-YL)THIO)METHYL)-6-(4-(HYDROXYMETHYL)PHENYL)-1,3-DIOXAN-2-YL)PHENYL)-N8-HYDROXYOCTANEDIAMIDE|N-[4-[(2R,4R,6S)-4-[[(4,5-DIPHENYL-2-OXAZOLYL)THIO]METHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|C41H43N3O7S|OCTANEDIAMIDE, N1-(4-((2R,4R,6S)-4-(((4,5-DIPHENYL-2-OXAZOLYL)THIO)METHYL)-6-(4-(HYDROXYMETHYL)PHENYL)-1,3-DIOXAN-2-YL)PHENYL)-N8-HYDROXY-, REL-|UNII-02C2G1D30D COMPONENT BHUZLJOUHMBZQY-YXQOSMAKSA-N|NCGC00346840-03|CS-5738|N-[4-[(2R,4R,6S)-4-[[4,5-DI(PHENYL)-1,3-OXAZOL-2-YL]SULFANYLMETHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|N-[4-[(2R,4R,6S)-4-[(4,5-DIPHENYL-1,3-OXAZOL-2-YL)SULFANYLMETHYL]-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL]PHENYL]-N'-HYDROXYOCTANEDIAMIDE|N-(4-{(2R,4R,6S)-4-{[(4,5-DIPHENYL-1,3-OXAZOL-2-YL)SULFANYL]METHYL}-6-[4-(HYDROXYMETHYL)PHENYL]-1,3-DIOXAN-2-YL}PHENYL)-N -HYDROXYOCTANEDIAMIDE|AKOS024457607|TUBACIN|KS-0000185J|BDBM22449	-	PUBCHEM	6675804	C41H43N3O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BHUZLJOUHMBZQY-YXQOSMAKSA-N
29553	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Blackburn C (2014)	25454270	224857	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29554	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9526	N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamide	2-[5-(3-NITROPHENYL)FURFURYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-7-CARBOHYDROXIMIC ACID|BDBM50027664	-	PUBCHEM	101882265	C21H19N3O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PMFDRULHDRRWFP-UHFFFAOYSA-N
29555	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9466	(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	(R)-7BETA-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-2-CARBOHYDROXIMIC ACID|BDBM50027662	-	PUBCHEM	92045024	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-QGZVFWFLSA-N
29556	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tang G (2014)	25238284	224858	9527	(7S)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamide	BDBM50027661	-	PUBCHEM	118715268	C20H19N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MWLFQRZKKHIDTM-KRWDZBQOSA-N
29557	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9528	N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamide	BDBM50026431	-	PUBCHEM	118714377	C21H23N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GIMAODGURWKHJY-UHFFFAOYSA-N
29558	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9529	N-Hydroxy-5-(1-phenylpyrazol-3-yl)pentanamide	BDBM50026430	-	PUBCHEM	118714371	C14H17N3O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SRBLEOJYOQUWOH-UHFFFAOYSA-N
29559	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	9530	5-[1-[(4-Anilinophenyl)methyl]pyrazol-3-yl]-N-hydroxypentanamide	BDBM50026429	-	PUBCHEM	118714376	C21H24N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XXOUJCCBKBTDDB-UHFFFAOYSA-N
29560	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Yao Y (2014)	25218912	224859	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29561	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Salvador LA (2014)	25147612	224860	9531	(5R,8S,11S)-5-Methyl-11-[(E)-4-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]but-1-enyl]-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trione	BDBM50101331	-	PUBCHEM	118712502	C42H54N8O8S6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VXQMEGLYMWVBHB-UOLLFOIHSA-N
29562	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Salvador LA (2014)	25147612	224860	9532	Largazole Thiol	LARGAZOLE THIOL|BDBM50020912	-	PUBCHEM	56663191	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-FJNFOTEGSA-N
29574	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9544	(E)-N-Hydroxy-3-[4-[[5-(naphthalen-1-ylmethyl)-1,3,4-oxadiazol-2-yl]methyl]phenyl]prop-2-enamide	N-HYDROXY-3-[4-[5-(1-NAPHTHYLMETHYL)-1,3,4-OXADIAZOLE-2-YLMETHYL]PHENYL]PROPENEAMIDE|BDBM50047967	-	PUBCHEM	102366363	C23H19N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	DQHBWINPWGGELF-OUKQBFOZSA-N
29575	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9545	(E)-N-Hydroxy-3-[4-[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]phenyl]prop-2-enamide	BDBM50047966	-	PUBCHEM	118707836	C20H16N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MTSNUBCDRYSBCQ-JXMROGBWSA-N
29576	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	9546	(E)-N-Hydroxy-3-[4-[5-(naphthalen-1-ylmethyl)-1,3,4-oxadiazol-2-yl]phenyl]prop-2-enamide	BDBM50047965	-	PUBCHEM	118707835	C22H17N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LBRVMWDZJHBLGD-JLHYYAGUSA-N
29577	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Valente S (2014)	24972008	224864	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29578	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Chen F (2014)	24944733	224865	9532	Largazole Thiol	LARGAZOLE THIOL|BDBM50020912	-	PUBCHEM	56663191	C21H28N4O4S3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VEDPEVJAYWVUSJ-FJNFOTEGSA-N
29586	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9553	N-[7-(Hydroxyamino)-7-oxoheptyl]-2-methoxyquinoline-6-carboxamide	BDBM50044648	-	PUBCHEM	117829456	C18H23N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VVZXDYPDBYYVAY-UHFFFAOYSA-N
29587	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9554	N-[7-(Hydroxyamino)-7-oxoheptyl]-1-methyl-2-oxoquinoline-6-carboxamide	BDBM50044646	-	PUBCHEM	117829462	C18H23N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FVXNWIVUIWQBNB-UHFFFAOYSA-N
29588	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9555	N-[7-(Hydroxyamino)-7-oxoheptyl]-4,4-dimethyl-2-oxo-1,3-dihydroquinoline-6-carboxamide	BDBM50044645	-	PUBCHEM	86581005	C19H27N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OEQQELYWLWKXKU-UHFFFAOYSA-N
29589	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9556	N'-Hydroxy-N-(2-oxo-1H-quinolin-6-yl)octanediamide	BDBM50044640	-	PUBCHEM	117829479	C17H21N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMKXBBIZQUFLCC-UHFFFAOYSA-N
29590	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Tashima T (2014)	24864038	224867	9557	BDBM50033636	-	-	CHEMBL	CHEMBL3309297	C22H29N3O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RIHKXPFNMAZMOA-KTRQRASZSA-N
29596	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	9393	Ricolinostat	SW219836-1|ZINC89630354|W-5979|AS-73344|D10661|ROCILINOSTAT (ACY-1215)|GTPL7010|ROCILINOSTAT|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]PYRIMIDINE-5-CARBOXAMIDE|ACY-63|DTXSID40157148|RICOLINOSTAT (USAN/INN)|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)-|CCG-269054|AK151416|7-{[2-(DIPHENYLAMINO)PYRIMIDIN-5-YL]FORMAMIDO}-N-HYDROXYHEPTANAMIDE|SMR004702950|EX-A139|UNII-WKT909C62B|ACN-030031|S8001|AH4|CS-0965|DB12376|Q27088553|NS00073045|ACY-1215|1316214-52-4|SB17054|CC-661|HMS3426C09|US8609678, 2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE [26]|AB0032517|BCP06028|A11940|X5832|AC-30258|2-(DIPHENYLAMINO)-N-(7-(HYDROXYAMINO)-7-OXOHEPTYL)PYRIMIDINE-5-CARBOXAMIDE|MLS006011181|N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-2-(N-PHENYLANILINO)PYRIMIDINE-5-CARBOXAMIDE|HY-16026|WKT909C62B|NCGC00345802-05|J-690127|ACY1215|AX8288032|AKOS024259260|RICOLINOSTAT (ACY-1215)|RICOLINOSTAT [USAN:INN]|2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-5-PYRIMIDINECARBOXAMIDE|5-PYRIMIDINECARBOXAMIDE, 2-(DIPHENYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]-|NCGC00345802-01|RICOLINOSTAT|HMS3653F17|KS-00000SAV|BDBM50439674	-	PUBCHEM	53340666	C24H27N5O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QGZYDVAGYRLSKP-UHFFFAOYSA-N
29597	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	9561	(E)-N-Hydroxy-3-(3-pyrrolo[2,3-b]pyridin-1-ylsulfonylphenyl)prop-2-enamide	N-HYDROXY-3-[3-(1H-PYRROLO[2,3-B]PYRIDINE-1-YLSULFONYL)PHENYL]PROPENEAMIDE|(E)-N-HYDROXY-3-(3-PYRROLO[2,3-B]PYRIDIN-1-YLSULFONYLPHENYL)PROP-2-ENAMIDE|BDBM50015233	-	PUBCHEM	86765212	C16H13N3O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	OXPJGPURVBXIAP-VOTSOKGWSA-N
29598	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee HY (2014)	24766560	224871	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29601	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	9562	(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamide	(E)-N-HYDROXY-3-[4-(4-METHOXYPHENYL)PHENYL]PROP-2-ENAMIDE|N-HYDROXY-E-3-(4''-METHOXYBIPHENYL-4-YL)-ACRYLAMIDE|BDBM50293361	-	PUBCHEM	15986509	C16H15NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WKQPXLKFQLGQSM-NYYWCZLTSA-N
29602	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	9563	(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamide	N-HYDROXY-E-3-(4''-HYDROXYBIPHENYL-4-YL)-ACRYLAMIDE|(E)-N-HYDROXY-3-[4-(4-HYDROXYPHENYL)PHENYL]PROP-2-ENAMIDE|BDBM50293358	-	PUBCHEM	15986418	C15H13NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MGGQEULGVBEMAL-XCVCLJGOSA-N
29603	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29604	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Cincinelli R (2014)	24742384	224873	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29605	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Li X (2014)	24694055	224874	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29606	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Taddei M (2014)	24588105	224875	9564	1-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-[4-(morpholin-4-ylmethyl)phenyl]triazole-4-carboxamide	BDBM50008222	-	PUBCHEM	90655296	C30H40N6O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IBHAGSBJXPUIFA-UHFFFAOYSA-N
29607	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Taddei M (2014)	24588105	224875	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29608	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Baruchello R (2014)	24565573	224876	9565	5-(2,4-Dihydroxy-5-propan-2-ylbenzoyl)-N-[7-(hydroxyamino)-7-oxoheptyl]-6,7-dihydro-4H-[1,2]oxazolo[4,5-c]pyridine-3-carboxamide	BDBM50007730	-	PUBCHEM	86302594	C24H32N4O7	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MSHYQCFSRGHYAU-UHFFFAOYSA-N
29609	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Baruchello R (2014)	24565573	224876	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29613	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18440229	224878	9568	1-[5-(2,3-Dihydro-1H-indol-1-ylcarbonyl)thiophen-2-yl]-2,2-difluoroethan-1-one	THIOPHENE DERIVATIVE, 15H|1-[5-(2,3-DIHYDRO-1H-INDOL-1-YLCARBONYL)THIOPHEN-2-YL]-2,2-DIFLUOROETHAN-1-ONE|BDBM25172	-	PUBCHEM	25023808	C15H11F2NO2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WZGNPOPOCGTSMZ-UHFFFAOYSA-N
29614	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18440229	224878	9569	CID 24857909	THIOPHENE DERIVATIVE, 3I|N-METHYL-N-(QUINOXALIN-6-YLMETHYL)-5-(2,2,2-TRIFLUOROACETYL)THIOPHENE-2-CARBOXAMIDE|BDBM25163	-	PUBCHEM	24857909	C17H12F3N3O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RLNCISDDCDFAHS-UHFFFAOYSA-N
29615	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	9570	4-[[1-(3-Aminopropyl)triazol-4-yl]methylamino]-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	BDBM50377688	-	PUBCHEM	44449588	C20H31N7O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VYBKJKUFXIAVJM-UHFFFAOYSA-N
29616	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	9571	5-[3-[4-[[4-[[7-(Hydroxyamino)-7-oxoheptyl]carbamoyl]anilino]methyl]triazol-1-yl]propylcarbamothioylamino]-2-(3-oxoxanthen-9-yl)benzoic acid	BDBM50377687	-	PUBCHEM	44448637	C41H42N8O7S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SIKVCWVCYQGEQT-UHFFFAOYSA-N
29617	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29618	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Mazitschek R (2008)	18430569	224879	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29619	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Nakao Y (2008)	18397826	224880	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29624	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18370373	224883	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29625	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	4802	Belinostat	UNII-F4H96P17NZ|NSC-726630|ZINC3818726|ABP000140|866323-14-0|SC-71101|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|SW219445-1|NSC726630|BELEODAQ|BCPP000351|EX-A180|PX 105684|QCR-181|BCP01741|BRD-K17743125-001-01-9|GTPL7496|(E)-N-HYDROXY-3-(3-(N-PHENYLSULFAMOYL)PHENYL)ACRYLAMIDE|BELINOSTAT - PXD101|SB16466|CC-489|AOB87787|BELINOSTAT|AX8144528|MLS006011091|AC-25046|AB0007889|BELINOSTAT (PXD101)|BELINOSTAT,PXD101, PX105684|W-5363|(E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE|414864-00-9|D08870|(E)-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENEHYDROXAMIC ACID|BELINOSTAT [USAN:INN]|SMR004702879|Q4882925|E-BELINOSTAT|BELINOSTAT (PXD101)|PXD101|PXD 101|N-HYDROXY-3-(3-PHENYLSULPHAMOYLPHENYL)ACRYLAMIDE|API0003555|BELINOSTAT (USAN/INN)|(2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]ACRYLAMIDE|BELEODAQ (TN)|PUBCHEM22405|NCGC00263155-05|(E)-N-HYDROXY-3-(3-PHENYLSULFAMOYL-PHENYL)-ACRYLAMIDE|PXD-101|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PR|S1085|LS41098|PX-105684|BELINOSTAT PH3|N-HYDROXY-3-(3-PHENYLSULFAMOYLPHENYL)ACRYLAMIDE|EC-000.2286|BELINOSTAT/PXD101,PX105684/|5OG|DTXSID60194378|2-PROPENAMIDE, N-HYDROXY-3-(3-((PHENYLAMINO)SULFONYL)PHENYL)-, (2E)-|BCP9000386|PX105684|F4H96P17NZ|N-HYDROXY-3-[(PHENYLAMINO)SULFONYL]-TRANS-CINNAMAMIDE|AS-17068|BELINOSTAT(RANDOM CONFIGURATION)|A25012|N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-2-PROPENAMIDE|AKOS025401741|N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE|CCG-208758|2-PROPENAMIDE, N-HYDROXY-3-[3-[(PHENYLAMINO)SULFONYL]PHENYL]-, (2E)-|DB05015|J-523584|BDBM25150	beleodaq	DRUGBANK	DB05015	C15H14N2O4S	small molecule	L01XX49	866323-14-0	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NCNRHFGMJRPRSK-MDZDMXLPSA-N
29626	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	9576	Dacinostat	AS-74728|(2E)-N-HYDROXY-3-(4-{[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL}PHENYL)PROP-2-ENAMIDE|S1095|ABP000476|AOB87324|SB19288|404951-53-7|Z-3310|(2E)-N-HYDROXY-3-[4-({(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO}METHYL)PHENYL]PROP-2-ENAMIDE|MLS006011098|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-2-PROPENAMIDE|LAQ824 (NVP-LAQ824,DACINOSTAT)|AK174336|139303-EP2292617A1|EX-A2226|LAQ824; DACINOSTAT; NVP-LAQ824|ZINC1494627|Q27076972|DACINOSTAT (NVP-LAQ824, LAQ824)|V10P524501|BCP9000839|UNII-V10P524501|2-PROPENAMIDE, N-HYDROXY-3-[4-[[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-, (2E)-|A825135|LAQ824 (DACINOSTAT)|139303-EP2270008A1|X7607|BRD-K56957086-001-02-2|DACINOSTAT [INN]|LAQ824/|CS-1974|X7530|LS-192513|NVP-LAQ824|(2E)-N-HYDROXY-3-(4-({(2-HYDROXYETHYL)(2-(1H-INDOL-3-YL)ETHYL)AMINO}METHYL)PHENYL)PROPENAMIDE|HY-13606|DTXSID1041055|EC-000.2469|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METH YL]PHENYL]PROP-2-ENAMIDE|NVP-LAQ 824|GTPL7497|2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-HYDROXYETHYL)(2-(1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-|LAQ824,NVP-LAQ824|LAQ-824|CCG-208761|LAQ824|SMR004701446|N-HYDROXY-3-[4-[[(2-HYDROXYETHYL)[2-(1H-INDOL-3-YL)ETHYL]-AMINO]METHYL]PHENYL]-2E-2-PROPENAMIDE|SW219385-1|SMR004702886|BCP01747|(E)-N-HYDROXY-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]PROP-2-ENAMIDE|AKOS015899788|DACINOSTAT|MLS006010418|(E)-3-[4-[[2-HYDROXYETHYL-[2-(1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-N-OXIDANYL-PROP-2-ENAMIDE|BDBM19428	-	PUBCHEM	6445533	C22H25N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BWDQBBCUWLSASG-MDZDMXLPSA-N
29627	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2008)	18308563	224884	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29632	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	9580	2-Propenamide, N-hydroxy-3-(4-(((2-hydroxyethyl)(2-(1H-indol-2-yl)ethyl)amino)methyl)phenyl)-	591207-53-3|LAQ 824|2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-HYDROXYETHYL)(2-(1H-INDOL-2-YL)ETHYL)AMINO)METHYL)PHENYL)BDBM50372470	-	PUBCHEM	44456564	C22H25N3O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FGJCGXHQLHHNFO-MDZDMXLPSA-N
29633	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	9581	(2S)-2-[(1-Methylpiperidin-2-yl)amino]-8-oxo-N-(4-phenyl-1,3-thiazol-2-yl)nonanamide	BDBM50372446	-	PUBCHEM	44456965	C24H34N4O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KQYOQEZNUIXORM-AIBWNMTMSA-N
29634	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Paris M (2008)	18247554	224886	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29635	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Witter DJ (2008)	18060775	114009	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29636	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Schaefer S (2008)	18054239	123981	9582	6-[(3S,9S,12R)-3-Benzyl-6,6-dimethyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]-N-hydroxyhexanamide	6-((5S,11S,13AR)-5-BENZYL-8,8-DIMETHYL-4,7,10,13-TETRAOXO-TETRADECAHYDRO-3A,6,9,12-TETRAAZA-CYCLOPENTACYCLODODECEN-11-YL)-HEXANOIC ACID HYDROXYAMIDE|6-((9S,13AR)-5-(S)-1-BENZYL-8,8-DIMETHYL-4,7,10,13-TETRAOXO-TETRADECAHYDRO-3A,6,9,12-TETRAAZA-CYCLOPENTACYCLODODECEN-11-YL)-HEXANOIC ACID HYDROXYAMIDE|BDBM50154337	-	PUBCHEM	9806551	C26H37N5O6	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XWZYWFHHLWISBR-SLFFLAALSA-N
29640	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Lee S (2007)	17588744	224889	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29641	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9585	N-[4-[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID [2''-(2-AMINO-3-PHENYLPROPIONYLAMINO)-BIPHENYL-4-YL]AMIDE HYDROXYAMIDE|BDBM50214441	-	PUBCHEM	16733294	C29H34N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	SZYFHRXJYNBDKS-VWLOTQADSA-N
29642	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9586	N-[4-[2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID {2''-[2-AMINO-3-(4-HYDROXY-PHENYL)PROPIONYLAMINO]BIPHENYL-4-YL}AMIDE HYDROXYAMIDE|BDBM50214439	-	PUBCHEM	16733417	C29H34N4O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BKQJCMOVBFAIQR-VWLOTQADSA-N
29643	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9587	N-[4-[2-[[(2S)-2-Amino-3-(1H-indol-3-yl)propanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamide	OCTANEDIOIC ACID {2''-[2-AMINO-3-(1H-INDOL-3-YL)PROPIONYLAMINO]BIPHENYL-4-YL}AMIDE HYDROXYAMIDE|BDBM50214436	-	PUBCHEM	16733410	C31H35N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ACGVFMBQNSCSQI-SANMLTNESA-N
29644	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9588	1-(4-(Dimethylamino)phenyl)-3-(7-(hydroxyamino)-7-oxoheptyl)urea	7-[[4-(DIMETHYLAMINO)PHENYL]CARBAMOYLAMINO]-N-HYDROXYHEPTANAMIDE|1-(4-(DIMETHYLAMINO)PHENYL)-3-(7-(HYDROXYAMINO)-7-OXOHEPTYL)UREA|7-[3-(4-DIMETHYLAMINO-PHENYL)-UREIDO]-HEPTANOIC ACID HYDROXYAMIDE|7-[3-(4-DIMETHYLAMINOPHENYL)-UREIDO]HEPTANOIC ACID HYDROXYAMIDE|BDBM50214433	-	PUBCHEM	11558827	C16H26N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	ZYOHRYKXMFPCNU-UHFFFAOYSA-N
29645	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9589	N'-Hydroxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]octanediamide	OCTANEDIOIC ACID HYDROXYAMIDE [4-(3-NITRO-PHENYL)THIAZOL-2-YL]AMIDE|N'-HYDROXY-N-[4-(3-NITROPHENYL)-1,3-THIAZOL-2-YL]OCTANEDIAMIDE|BDBM50214432	-	PUBCHEM	16733411	C17H20N4O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LJFNWCGSOPRFNA-UHFFFAOYSA-N
29646	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9590	3-[[4-(Dimethylamino)phenyl]methylcarbamoylamino]-N-hydroxypropanamide	8-[3-(4-DIMETHYLAMINOBENZYL)UREIDO]OCTANOIC ACID HYDROXYAMIDE|BDBM50214431	-	PUBCHEM	16733415	C13H20N4O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FJIZCQBWUCHHAR-UHFFFAOYSA-N
29647	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Kozikowski AP (2007)	17539623	115857	9591	N-(Quinolin-8-YL)-6-(2-sulfanylacetamido)hexanamide	828920-13-4|6-(2-MERCAPTOACETYLAMINO)-HEXANOIC ACID QUINOLIN-8-YLAMIDE|N-(8-QUINOLYL)-6-[(MERCAPTOACETYL)AMINO]HEXANAMIDE|N-(QUINOLIN-8-YL)-6-(2-SULFANYLACETAMIDO)HEXANAMIDE|N-QUINOLIN-8-YL-6-[(2-SULFANYLACETYL)AMINO]HEXANAMIDE|HEXANAMIDE, 6-[(MERCAPTOACETYL)AMINO]-N-8-QUINOLINYL-|CTK3D5606|6-(2-MERCAPTO-ACETYLAMINO)-HEXANOIC ACID QUINOLIN-8-YLAMIDE|DTXSID10587453|6-(2-MERCAPTOACETAMIDO)-N-(QUINOLIN-8-YL)HEXANAMIDE|BDBM50161470	-	PUBCHEM	16733414	C17H21N3O2S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KQBNGYXGCIUPHR-UHFFFAOYSA-N
29700	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2006)	16987657	224901	9637	(2S)-N'-Hydroxy-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-N-[2-(2-phenyl-1H-indol-3-yl)ethyl]octanediamide	(S)-N8-HYDROXY-2-(2-(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETAMIDO)-N1-(2-(2-PHENYL-1H-INDOL-3-YL)ETHYL)OCTANEDIAMIDE|(2S)-N'-HYDROXY-2-[[2-(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETYL]AMINO]-N-[2-(2-PHENYL-1H-INDOL-3-YL)ETHYL]OCTANEDIAMIDE|BDBM50195108	-	PUBCHEM	11664499	C36H41N5O5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VBWCMILVHANAGG-YTTGMZPUSA-N
29701	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jones P (2006)	16987657	224901	9638	N-[(2S)-1,8-Dioxo-1-[(4-phenyl-1,3-thiazol-2-yl)amino]nonan-2-yl]-1-methylpiperidine-2-carboxamide	(2S)-2-[(1-METHYLPIPERIDIN-2-YL)FORMAMIDO]-8-OXO-N-(4-PHENYL-1,3-THIAZOL-2-YL)NONANAMIDE|N-[(2S)-1,8-DIOXO-1-[(4-PHENYL-1,3-THIAZOL-2-YL)AMINO]NONAN-2-YL]-1-METHYLPIPERIDINE-2-CARBOXAMIDE|BIS-AMIDE INHIBITOR, 15|BDBM25144	-	PUBCHEM	16036765	C25H34N4O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	MVGAXXKEFDOLGL-AIBWNMTMSA-N
29734	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9668	Tert-butyl N-[(2S)-1-(cycloheptylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOHEPTYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|TERT-BUTYL N-[(2S)-1-(CYCLOHEPTYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|THIOLATE ANALOGUE, 18A|BDBM19136	-	PUBCHEM	11844893	C19H36N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTVMPAGMFUPGRI-INIZCTEOSA-N
29735	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9669	Tert-butyl N-[(2S)-1-(cyclohexylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOHEXYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|THIOLATE ANALOGUE, 17A|TERT-BUTYL N-[(2S)-1-(CYCLOHEXYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|BDBM19135	-	PUBCHEM	11844892	C18H34N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	NREURQUIJSGJMZ-HNNXBMFYSA-N
29736	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	9670	Tert-butyl N-[(2S)-1-(cyclopentylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamate	TERT-BUTYL N-[(1S)-1-(CYCLOPENTYLCARBAMOYL)-6-SULFANYLHEXYL]CARBAMATE|TERT-BUTYL N-[(2S)-1-(CYCLOPENTYLAMINO)-1-OXO-7-SULFANYLHEPTAN-2-YL]CARBAMATE|THIOLATE ANALOGUE, 16A|BDBM19134	-	PUBCHEM	11844891	C17H32N2O3S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IKSFNOMXHPMYIQ-AWEZNQCLSA-N
29737	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Suzuki T (2006)	16884291	224905	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29755	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Shinji C (2005)	16137884	224909	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29798	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Jose B (2004)	15454224	224914	4124	Trichostatin A	LS-74195|ANTIBIOTIC A-300|CCG-208142|NCGC00162453-05|TRICHOSTATIN A, >=98% (HPLC), FROM STREPTOMYCES SP.|A 300|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE|MFCD03848392|SW219664-1|[R-(E,E)]-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|HMS3649O20|3X2S926L3Z|HMS1792L09|ABP000141|HMS1362L09|HY-15144|Q-201864|TRICHLOSTATIN A|3C10|NCGC_TSA|AS-74315|HMS1990L09|AKOS015899840|SC-73346|SR-05000013796-3|ZINC100014731|BRD-K68202742-001-05-8|TRICHOSTATIN A??, VETEC(TM) REAGENT GRADE, FROM STREPTOMYCES SP., >=98%|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENEHYDROXAMIC ACID|7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|(2E,4E,6R)-7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE|TRICHOSTATIN A FROM STREPTOMYCES SP.|Q425894|GTPL7005|C17H22N2O3|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHEN YL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMID E|S1045|DB04297|7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TRICHOSTATIN A/TSA|NCGC00162453-15|(2E,4E,6R)-7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXOHEPTA-2,4-DIENAMIDE|ZX-AFC000233|(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE|TSN|SGCTO-002|NCGC00162453-03|NCGC00162453-01|TRICOSTATIN A|M984|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|BRD-K68202742-001-04-1|TRICHOSTATINE A|880T196|1C3R|TRICHOSTATIN|TRICHOSTATIN-A - TSA|TRICHOSTATIN A,TSA|W-5309|(R)-TRICHOSTATIN A|HMS3403L09|UNII-30RHG284Z4 COMPONENT RTKIYFITIVXBLE-QEQCGCAPSA-N|CCG-208681|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)- (9CI)|58880-19-6|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, [R-(E,E)]-|SR-05000013796|NCGC00162453-04|GNF-PF-1011|BCP01776|M02571|TRICHOSTATIN(S)|SMR004702883|MLS006011095|EX-A1665|DTXSID6037063|NCGC00162453-02|A-300-I|UNII-3X2S926L3Z|3F0R|CS-0499|A8183|BCPP000035|SB17023|2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-|(6R)-N-HYDROXY-4,6-DIMETHYL-7-OXO-7-[4-(DIMETHYLAMINO)PHENYL]-2,4-HEPTADIENAMIDE|2,4-HEPTADIENAMIDE, 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|2,4-HEPTADIENAMIDE,7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-, (2E,4E,6R)-|TRICHOSTATIN A (TSA)|LMPK01000055|CC-238|TRICHOSTATIN A|TSA|BDBM19130	-	DRUGBANK	DB04297	C17H22N2O3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RTKIYFITIVXBLE-QEQCGCAPSA-N
29807	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	unknown	target	Wu TY (2004)	14698179	224917	2443	Vorinostat	Vorinostatum|SAHA|Suberoylanilide hydroxamic acid|Octanedioic acid hydroxyamide phenylamide|Zolinza|Suberanilohydroxamic acid|SHH|BDBM19149	zolinza	DRUGBANK	DB02546	C14H20N2O3	small molecule	L01XX38	149647-78-9	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WAEXFXRVDQXREF-UHFFFAOYSA-N
29835	107920	1540	HSPC057	CYLD	BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2	9606	Homo sapiens	inhibitor	target	Yamanaka S (2021)	33390248	226776	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MZBFFXLYQTWKNV-INIZCTEOSA-N
29848	114402	8883	HPP1	NAE1	A-116A10.1|APPBP1|ula-1	9606	Homo sapiens	inhibitor	target	Yoshimura C (2019)	31092565	228648	9877	TAS4464	7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[5-[(aminosulfonyl)amino]-5-deoxy-beta-D-ribofuranosyl]-5-[2-(2-ethoxy-6-fluorophenyl)ethynyl]-|7-[5-Deoxy-5-(sulfamoylamino)-beta-D-ribofuranosyl]-5-[(2-ethoxy-6-fluorophenyl)ethynyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	-	CHEMSPIDER	75533883	C21H23FN6O6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	TZTRUHFXPVXWRD-QTQZEZTPSA-N
29883	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	inhibitor	target	Cai Q (2011)	21443232	228663	9886	AT-406	Pyrrolo[1,2-a][1,5]diazocine-8-carboxamide, N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-, (5S,8S,10aR)-|AT-406|N65WC8PXDD|(5S,8S,10aR)-N-(Diphenylmethyl)-5-[(N-methyl-L-alanyl)amino]-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide	-	CHEMSPIDER	28424114	C32H43N5O4	small molecule	-	1071992-81-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSXUTRRVVSPWDZ-MKKUMYSQSA-N
29884	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Cai Q (2011)	21443232	228663	9886	AT-406	Pyrrolo[1,2-a][1,5]diazocine-8-carboxamide, N-(diphenylmethyl)decahydro-5-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-3-(3-methyl-1-oxobutyl)-6-oxo-, (5S,8S,10aR)-|AT-406|N65WC8PXDD|(5S,8S,10aR)-N-(Diphenylmethyl)-5-[(N-methyl-L-alanyl)amino]-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide	-	CHEMSPIDER	28424114	C32H43N5O4	small molecule	-	1071992-81-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LSXUTRRVVSPWDZ-MKKUMYSQSA-N
29919	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Ward GA (2018)	29695633	228671	9891	ASTX660	1-[6-(4-Fluorobenzyl)-5-(hydroxymethyl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-{[(3R)-3-methyl-4-morpholinyl]methyl}-1-piperazinyl]ethanone|Ethanone, 1-[6-[(4-fluorophenyl)methyl]-2,3-dihydro-5-(hydroxymethyl)-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methyl-4-morpholinyl]methyl]-1-piperazinyl]-	-	CHEMSPIDER	71061559	C30H42FN5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YCXOHEXZVKOGEV-DNRQZRRGSA-N
29922	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	inhibitor	target	Hennessy EJ (2013)	24320998	228672	9883	AZD5582	AZD5582|AZD 5582|2-Pyrrolidinecarboxamide, N,N'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-, (2S,2'S)-	-	CHEMSPIDER	31133160	C58H78N8O8	small molecule	-	1258392-53-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WLMCRYCCYXHPQF-ZVMUOSSASA-N
29923	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Hennessy EJ (2013)	24320998	228672	9883	AZD5582	AZD5582|AZD 5582|2-Pyrrolidinecarboxamide, N,N'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-, (2S,2'S)-	-	CHEMSPIDER	31133160	C58H78N8O8	small molecule	-	1258392-53-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WLMCRYCCYXHPQF-ZVMUOSSASA-N
29926	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	inhibitor	target	Kester RF (2013)	24093940	165954	9862	LCL-161	N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N~2~-methylalaninamide|Propanamide, N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-, (2S)-|LCL-161|6TNS415Y3P	-	CHEMSPIDER	30687709	C26H33FN4O3S	small molecule	-	1005342-46-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UFPFGVNKHCLJJO-SSKFGXFMSA-N
29937	113041	7189	-	TRAF6	MGC:3310|RNF85	9606	Homo sapiens	inhibitor	target	Brenke JK (2018)	29950522	216477	9880	C25-140	1-Propanone, 3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-|1-(4-Benzyl-1-piperidinyl)-3-[3,5-dimethyl-1-(3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-propanone	-	CHEMSPIDER	29053655	C26H31N7O	small molecule	-	1358099-18-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HFKVRXVHZGBRKF-UHFFFAOYSA-N
29938	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Myrianthopoulos V (2016)	27049577	195311	9904	NSC232003	(5Z)-5-[1-(Hydroxyamino)ethylidene]-2,4(3H,5H)-pyrimidinedione|2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-, (5Z)-	-	CHEMSPIDER	4513358	C6H7N3O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IXSSYZRLNVZFMP-ARJAWSKDSA-N
29986	112372	6477	-	SIAH1	SIAH1A	9606	Homo sapiens	inhibitor	target	Zhang Q (2017)	27776223	199360	163	Menadione	Menadione|Vitamin K3|2-Methyl-1,4-naphthochinon|2-Methyl-1,4-Naphthalenedione|2-Methyl-1,4-naphthoquinone	-	DRUGBANK	DB00170	C11H8O2	small molecule	B02BA02	58-27-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJVAVZPDRWSRRC-UHFFFAOYSA-N
30015	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Liu J (2020)	32128407	228702	9767	Bivalent ligand 174	opto-dBET1|Bivalent_ligand_174	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: opto-dBET1 (CRBN:opto-pomalidomide --- BRD4:JQ1)	-
30023	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2020)	32128406	228703	9769	Bivalent ligand 176	PHOTAC-I-3|Bivalent_ligand_176	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
30032	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Takahashi D (2020)	31958028	228707	9801	Bivalent ligand 181	ARD-61|Bivalent_ligand_181	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-61 (VHL:HXD079 --- AR:ARi-16)	-
30034	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Takahashi D (2020)	31958028	228707	9801	Bivalent ligand 181	ARD-61|Bivalent_ligand_181	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111260	5241	-	PGR	NR3C3|PR	9606	Homo sapiens	target	Standardized BVL Name: ARD-61 (VHL:HXD079 --- PR:ARi-16)	-
30038	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smith BE (2019)	30631068	219514	9803	Bivalent ligand 183	SJFDelta|Bivalent_ligand_183	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111589	5603	RP1-179N16.4	MAPK13	MAPK 13|MAPK-13|PRKM13|SAPK4|p38delta	9606	Homo sapiens	target	Standardized BVL Name: SJF (VHL:ligand 7 ---MAPK13:Foretinib)	-
30045	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	An Z (2019)	30603959	228709	9798	Bivalent ligand 186	PROTAC NP8|Bivalent_ligand_186	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC NP8 (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
30047	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Wu H (2019)	31271281	228479	9797	Bivalent ligand 185	PROTAC 12d|Bivalent_ligand_185	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 12d (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
30063	114375	8850	-	KAT2B	CAF|P/CAF|PCAF	9606	Homo sapiens	degradation	target	Bassi ZI (2018)	30200762	228710	9799	Bivalent ligand 187	GSK699|Bivalent_ligand_187	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: GSK699 (CRBN:thalidomide --- KAT2B:GSK4027)	-
30067	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- AURKA:TAE684)	-
30071	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9756	Bivalent ligand 192	compound 9|Bivalent_ligand_192	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 9 (CRBN:pomalidomide --- PTK2:TAE684)	-
30077	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- AURKA:ceritinib)	-
30081	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Powell CE (2018)	29660984	228711	9755	Bivalent ligand 193	compound 11|Bivalent_ligand_193	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 11 (CRBN:pomalidomide --- PTK2:ceritinib)	-
30084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121316	57001	DC11	ACN9	SDHAF3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- SDHAF3:foretinib)	-
30086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121596	57537	-	SORCS2	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- SORCS2:foretinib)	-
30088	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108474	2177	-	FANCD2	FA-D2|FA4|FACD|FAD|FAD2|FANCD	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- FANCD2:foretinib)	-
30090	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116553	22887	-	FOXJ3	-	9606	Homo sapiens	target	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- FOXJ3:foretinib)	-
30094	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Girardini M (2019)	30826187	220662	9754	Bivalent ligand 194	PROTAC 14a|Bivalent_ligand_194	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 14a (VHL:VH032 ---CRBN:pomalidomide	-
30096	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Girardini M (2019)	30826187	220662	9753	Bivalent ligand 195	PROTAC 18b|Bivalent_ligand_195	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 18b (VHL:VH101 ---CRBN:pomalidomide)	-
30110	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9762	Bivalent ligand 198	compound 1|Bivalent_ligand_198	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 1 (VHL:VHL-1 --- SNCA:BTA-1)	-
30112	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9761	Bivalent ligand 199	compound 4|Bivalent_ligand_199	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 4 (VHL:VHL-1 --- SNCA:BTA-1)	-
30114	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9787	Bivalent ligand 200	compound 5|Bivalent_ligand_200	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 5 (VHL:VHL-1 --- SNCA:BTA-1)	-
30116	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9786	Bivalent ligand 201	compound 7|Bivalent_ligand_201	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 7 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30118	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kargbo RB (2020)	32550983	228713	9785	Bivalent ligand 202	compound 34|Bivalent_ligand_202	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: compound 34 (VHL:VHL-1 --- SNCA:SNCA ligand)	-
30125	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9782	Bivalent ligand 205	JP1|Bivalent_ligand_205	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP1 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30127	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9781	Bivalent ligand 206	JP2|Bivalent_ligand_206	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP2 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30129	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9780	Bivalent ligand 207	JP3|Bivalent_ligand_207	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP3 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30131	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9795	Bivalent ligand 208	JP4|Bivalent_ligand_208	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP4 (XIAP:Boc-IAP --- JAK1:pyrimidine)	-
30133	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9794	Bivalent ligand 209	JP5|Bivalent_ligand_209	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP5 (XIAP:Boc-IAP --- JAK1:quinoxaline)	-
30135	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9824	Bivalent ligand 210	JP6|Bivalent_ligand_210	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP6 (XIAP:Boc-IAP --- JAK1:quinoxaline)	-
30137	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9782	Bivalent ligand 205	JP1|Bivalent_ligand_205	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP1 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30139	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9781	Bivalent ligand 206	JP2|Bivalent_ligand_206	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP2 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30141	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9780	Bivalent ligand 207	JP3|Bivalent_ligand_207	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP3 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30143	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9795	Bivalent ligand 208	JP4|Bivalent_ligand_208	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP4 (XIAP:Boc-IAP --- JAK2:pyrimidine)	-
30145	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9794	Bivalent ligand 209	JP5|Bivalent_ligand_209	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP5 (XIAP:Boc-IAP --- JAK2:quinoxaline)	-
30147	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Shah RR (2020)	32001089	227145	9824	Bivalent ligand 210	JP6|Bivalent_ligand_210	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JP6 (XIAP:Boc-IAP --- JAK2:quinoxaline)	-
30148	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EED: EED ligand)	-
30150	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EED: EED ligand)	-
30152	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- EZH2: EED ligand)	-
30154	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- EZH2: EED ligand)	-
30156	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9825	Bivalent ligand 211	PROTAC 1|Bivalent_ligand_211	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 1 (VHL:VH032 --- SUZ12: EED ligand)	-
30158	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hsu JH (2020)	31786184	226149	9826	Bivalent ligand 212	PROTAC 2|Bivalent_ligand_212	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 2 (VHL:VH032 --- SUZ12: EED ligand)	-
30161	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	degradation	target	You I (2020)	31859249	224930	9827	Bivalent ligand 213	INY-03-041|Bivalent_ligand_213	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-03-041 (CRBN:lenalidomide --- AKT1:GDC-0068)	-
30171	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30173	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30175	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- HDAC1-FKBP12F36V:AP1867)	-
30177	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- HDAC1-FKBP12F36V:AP1867)	-
30179	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- MYC-FKBP12F36V:AP1867)	-
30181	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- MYC-FKBP12F36V:AP1867)	-
30183	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- PLK1-FKBP12F36V:AP1867)	-
30185	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- PLK1-FKBP12F36V:AP1867)	-
30187	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30189	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- EZH2-FKBP12F36V:AP1867)	-
30197	112404	6513	-	SLC2A1	DYT17|DYT18|DYT9|EIG12|GLUT|GLUT-1|GLUT1|GLUT1DS|HTLVR|PED	9606	Homo sapiens	degradation	target	Bensimon A (2020)	32386596	223637	9832	Bivalent ligand 218	PROTAC dTAG13|Bivalent_ligand_218	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC dTAG13 (CRBN:phthalimide --- SLC2A1-FKBP12F36V:AP1867)	-
30218	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9788	Bivalent ligand 221	vRucaparib-TP3|Bivalent_ligand_221	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: vRucaparib-TP3 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30220	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang S (2019)	31659317	228718	9791	Bivalent ligand 222	vRucaparib-TP4|Bivalent_ligand_222	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	target	Standardized BVL Name: vRucaparib-TP4 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30237	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Manda S (2020)	32340152	228719	9818	Bivalent ligand 256	CPR3|Bivalent_ligand_256	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CPR3 (CRBN:pomalidomide --- Src:RBx10080307)	-
30239	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Manda S (2020)	32340152	228719	9831	Bivalent ligand 226	CPR4|Bivalent_ligand_226	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CPR4 (CRBN:pomalidomide --- Src:RBx10080307)	-
30246	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Testa A (2020)	31746102	228721	9834	Bivalent ligand 230	macroPROTAC-1|Bivalent_ligand_230	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: macroPROTAC1 (VHL:VH032 ---BRD4:JQ1)	-
30248	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Shibata N (2018)	28594553	228722	9835	Bivalent ligand 231	SNIPER(AR)-51/compound 42a|Bivalent_ligand_231	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(AR)-51/compound 42a (BIRC2:bestatin --- AR:AR antagonist-1)	-
30266	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9775	Bivalent ligand 240	vhhGFP4-VHL|Bivalent_ligand_240	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-VHL (VHL:vhhGFP4 --- H2B:GFP)	-
30276	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9775	Bivalent ligand 240	vhhGFP4-VHL|Bivalent_ligand_240	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-VHL (VHL:vhhGFP4 --- PCNA:GFP)	-
30292	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Han X (2019)	31804827	227993	9779	Bivalent ligand 244	ARD-266|Bivalent_ligand_244	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARD-266 (VHL:VHL-g --- AR:ARi-16)	-
30295	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	degradation	target	Vannam R (2021)	33400925	228723	9778	Bivalent ligand 245	dCBP-1|Bivalent_ligand_245	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dCBP-1 (CRBN:lenalidomide --- EP300:GNE-781)	-
30297	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	degradation	target	Vannam R (2021)	33400925	228723	9778	Bivalent ligand 245	dCBP-1|Bivalent_ligand_245	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dCBP-1 (CRBN:lenalidomide --- CREBBP:GNE-781)	-
30320	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Alabi S (2021)	33568647	228724	9815	Bivalent ligand 253	SJF-0628|Bivalent_ligand_253	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: SJF-0628 (VHL:HIF-1alpha hydroxyproline derived small molecule --- BRAF V600E mutant:vemurafenib)	-
30325	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Wu H (2019)	31271281	228479	9817	Bivalent ligand 255	Bivalent_ligand_255	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: (CRBN:pomalidomide  ---HDAC6:Nexturastat A)	-
30339	112404	6513	-	SLC2A1	DYT17|DYT18|DYT9|EIG12|GLUT|GLUT-1|GLUT1|GLUT1DS|HTLVR|PED	9606	Homo sapiens	degradation	target	Bensimon A (2020)	32386596	223637	8519	Bivalent ligand 131	PROTAC dTAG7|Bivalent_ligand_131	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC dTAG7 (CRBN:phthalimide --- SLC2A1-FKBP12F36V:AP1867)	-
30369	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Xue G (2019)	31566962	223639	8524	Bivalent ligand 134	pc-PROTAC1|Bivalent_ligand_134	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pc-PROTAC1 (CRBN:thalidomide --- BCR4:JQ1)	-
30388	115283	9958	-	USP15	UNPH-2|UNPH4	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 30	MZBFFXLYQTWKNV-INIZCTEOSA-N
30407	107920	1540	HSPC057	CYLD	BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 61	MZBFFXLYQTWKNV-INIZCTEOSA-N
30504	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Yokoo H (2020)	32631565	229142	10155	Bivalent ligand 257	POM-PERM3-R7|Bivalent_ligand_257	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: POM-PERM3-R7 (CRBN:pomalidomide ---ESR1:PERM3-R7)	-
30505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10144	Bivalent ligand 258	VH032-PERM3-R7|Bivalent_ligand_258	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: VH032-PERM3-R7 (VHL:VH032 ---AR:PERM3-R7)	-
30507	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10144	Bivalent ligand 258	VH032-PERM3-R7|Bivalent_ligand_258	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: VH032-PERM3-R7 (VHL:VH032 ---ESR1:PERM3-R7)	-
30512	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MV1-PERM3-R7 (XIAP:MV1 ---ESR1:PERM3-R7)	-
30513	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (BIRC2:MV1 ---AR:PERM3-R7)	-
30515	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10145	Bivalent ligand 259	MV1-PERM3-R7|Bivalent_ligand_259	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: MV1-PERM3-R7 (BIRC2:MV1 ---ESR1:PERM3-R7)	-
30520	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LCL-PERM3-R7 (XIAP:LCL161 ---AR:PERM3-R7)	-
30521	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (BIRC2:LCL161 ---ESR1:PERM3-R7)	-
30523	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Yokoo H (2020)	32631565	229142	10002	Bivalent ligand 260	LCL-PERM3-R7|Bivalent_ligand_260	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: LCL-PERM3-R7 (BIRC2:LCL161 ---ESR1:PERM3-R7)	-
30530	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Takahashi D (2019)	31606272	239579	10003	Bivalent ligand 263	AUTAC3|Bivalent_ligand_263	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 autophagosome recruiting moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: AUTAC3  (S-guanylation --- BRD4:JQ1)	-
30542	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- AURKA:TAE684)	-
30574	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK2:TAE684)	-
30576	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK4:TAE684)	-
30580	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK6:TAE684)	-
30608	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- LIMK1:TAE684)	-
30628	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30642	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PLK1:TAE684)	-
30644	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PLK4:TAE684)	-
30652	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- PTK2:TAE684)	-
30664	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- RPS6KB1:TAE684)	-
30672	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- SRC:TAE684)	-
30686	112904	7046	RP11-96L7.1	TGFBR1	AAT5|ACVRLK4|ALK-5|ALK5|ESS1|LDS1|LDS1A|LDS2A|MSSE|SKR4|TGFR-1|tbetaR-I	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- TGFBR1:TAE684)	-
30708	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10009	Bivalent Ligand 265	dAURK-4|Bivalent_Ligand_265	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dAURK-4 (CRBN:thalidomide---AURKA:Alisertib)	-
30711	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10012	Bivalent Ligand 266	FMF-05-178-1|Bivalent_Ligand_266	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: FMF-05-178-1 (VHL:VHL-1---BLK:XMD)	-
30713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10012	Bivalent Ligand 266	FMF-05-178-1|Bivalent_Ligand_266	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-05-178-1 (VHL:VHL-1--- CSK:XMD)	-
30720	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- AURKA:TAE684)	-
30740	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK2:TAE684)	-
30742	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK4:TAE684)	-
30746	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK6:TAE684)	-
30776	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- LIMK1:TAE684)	-
30790	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- MAPK7:TAE684)	-
30802	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- PLK4:TAE684)	-
30816	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- SRC:TAE684)	-
30838	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- AURKA:GNF-7)	-
30848	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- CDK4:GNF-7)	-
30870	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- LIMK1:GNF-7)	-
30894	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
30896	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
30898	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
30906	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- PLK1:GNF-7)	-
30908	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- PTK2:GNF-7)	-
30920	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- SRC:GNF-7)	-
30937	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1---AAK1:TAE)	-
30939	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ABL2:TAE)	-
30941	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- AURKA:TAE)	-
30943	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- AURKB:TAE)	-
30945	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107166	701	-	BUB1B	BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- BUB1B:TAE)	-
30947	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113914	8317	-	CDC7	CDC7L1|HsCDC7|Hsk1|huCDC7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDC7:TAE)	-
30949	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK1:TAE)	-
30951	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119715	51755	RP11-390P24.1	CDK12	CRK7|CRKR|CRKRS	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK12:TAE)	-
30953	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114176	8621	-	CDK13	CDC2L|CDC2L5|CHED|hCDK13	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK13:TAE)	-
30955	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK2:TAE)	-
30957	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK4:TAE)	-
30959	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDk6:TAE)	-
30961	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK7:TAE)	-
30963	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK9:TAE)	-
30965	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CHEK1:TAE)	-
30967	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107837	1453	-	CSNK1D	ASPS|CKIdelta|FASPS2|HCKID	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CSNK1D:TAE)	-
30969	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108355	2041	-	EPHA1	EPH|EPHT|EPHT1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- EPHA1:TAE)	-
30971	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- FER:TAE)	-
30973	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108551	2260	-	FGFR1	BFGFR|CD331|CEK|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- FGFR1:TAE)	-
30975	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- GAK:TAE)	-
30977	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119322	51135	RP11-210N13.4	IRAK4	IPD1|IRAK-4|NY-REN-64|REN64	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- IRAK4:TAE)	-
30979	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ITK:TAE)	-
30981	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- LIMK2:TAE)	-
30983	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAP4K2:TAE)	-
30985	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAP4K3:TAE)	-
30987	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAPK6:TAE)	-
30989	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MAPK7:TAE)	-
30991	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MARK4:TAE)	-
30993	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115171	9833	RP11-8N6.1	MELK	HPK38	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- MELK:TAE)	-
30995	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118978	29941	RP11-545E17.1	PKN3	-	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PKN3:TAE)	-
30997	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PLK4:TAE)	-
30999	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111549	5562	-	PRKAA1	AMPK|AMPKa1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PRKAA1:TAE)	-
31001	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PTK2:TAE)	-
31003	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111720	5753	-	PTK6	BRK	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- PTK6:TAE)	-
31005	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114468	8986	-	RPS6KA4	MSK2|RSK-B	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- RPS6KA4:TAE)	-
31007	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- SIK2:TAE)	-
31009	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- STK35:TAE)	-
31011	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- TNK2:TAE)	-
31013	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126088	127933	-	UHMK1	KIS|KIST|P-CIP2	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- UHMK1:TAE)	-
31015	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- ULK1:TAE)	-
31017	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- WEE1:TAE)	-
31022	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- AURKA:Ceritinib)	-
31026	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31034	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31048	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- GSK3B:Ceritinib)	-
31054	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31056	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31072	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- PTK2:Ceritinib)	-
31088	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- TBK1:Ceritinib)	-
31106	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- CDK4:GNF-7)	-
31120	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- LIMK1:GNF-7)	-
31130	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK14:GNF-7)	-
31132	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK8:GNF-7)	-
31134	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPK9:GNF-7)	-
31152	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- SRC:GNF-7)	-
31166	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- AURKA:Rebastinib)	-
31178	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK2:Rebastinib)	-
31180	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK4:Rebastinib)	-
31184	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK6:Rebastinib)	-
31196	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- LIMK1:Rebastinib)	-
31204	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- PLK4:Rebastinib)	-
31210	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- SRC:Rebastinib)	-
31238	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- CDK6:Ponatinib)	-
31252	109863	3654	-	IRAK1	IRAK|pelle	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- IRAK1:Ponatinib)	-
31268	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- MAPK14:Ponatinib)	-
31270	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- PDK1:Ponatinib)	-
31280	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- SRC:Ponatinib)	-
31287	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1---ABL1:GNF-7)	-
31289	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- ABL2:GNF-7)	-
31291	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- BLK:GNF-7)	-
31293	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CDK11B:GNF-7)	-
31295	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CDK4:GNF-7)	-
31297	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116290	11113	-	CIT	CRIK|STK21	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CIT:GNF-7)	-
31299	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- CSK:GNF-7)	-
31301	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- EPHA3:GNF-7)	-
31303	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- FER:GNF-7)	-
31305	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- GAK:GNF-7)	-
31307	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110124	3932	RP4-675E8.4	LCK	IMD22|LSK|YT16|p56lck|pp58lck	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1---a LCK:GNF-7)	-
31309	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- LIMK2:GNF-7)	-
31311	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP3K20:GNF-7)	-
31313	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112748	6885	RP1-154G14.1	MAP3K7	MEKK7|TAK1|TGF1a	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP3K7:GNF-7)	-
31315	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K1:GNF-7)	-
31317	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K2:GNF-7)	-
31319	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAP4K5:GNF-7)	-
31321	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK14:GNF-7)	-
31323	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK7:GNF-7)	-
31325	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPK9:GNF-7)	-
31327	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31329	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31331	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127209	149420	RP11-96L14.4	PDIK1L	CLIK1L|STK35L2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- PDIK1L:GNF-7)	-
31333	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- PTK2B:GNF-7)	-
31335	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- RIPK1:GNF-7)	-
31337	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31339	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- SIK2:GNF-7)	-
31341	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- STK35:GNF-7)	-
31343	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114750	9344	UNQ2971/PRO7431	TAOK2	MAP3K17|PSK|PSK1|PSK1-BETA|TAO1|TAO2	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- TAOK2:GNF-7)	-
31345	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- TNK2:GNF-7)	-
31347	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB1114 (VHL:VHL-1--- ULK1:GNF-7)	-
31349	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1---ABL1:GNF-7)	-
31351	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- ABL2:GNF-7)	-
31353	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107109	640	-	BLK	MODY11	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- BLK:GNF-7)	-
31355	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107421	984	-	CDK11B	CDC2L1|CDK11|CDK11-p110|CDK11-p46|CDK11-p58|CLK-1|PITSLREA|PK58|p58|p58CDC2L1|p58CLK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CDK11B:GNF-7)	-
31357	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CDK4:GNF-7)	-
31359	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107832	1445	-	CSK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- CSK:GNF-7)	-
31361	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108356	2042	-	EPHA3	EK4|ETK|ETK1|HEK|HEK4|TYRO4	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- EPHA3:GNF-7)	-
31363	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108532	2241	-	FER	FerT|PPP1R74|Pe1Fe10|Pe1Fe13|Pe1Fe3|Pe1Fe6|TYK3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- FER:GNF-7)	-
31365	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- GAK:GNF-7)	-
31367	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- LIMK1:GNF-7)	-
31369	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119725	51776	HCCS4	ZAK	AZK|MLK7|MLT|MLTK|MRK|mlklak|pk	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP3K20:GNF-7)	-
31371	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116354	11184	-	MAP4K1	HPK1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K1:GNF-7)	-
31373	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K2:GNF-7)	-
31375	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114063	8491	-	MAP4K3	GLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K3:GNF-7)	-
31377	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116353	11183	-	MAP4K5	GCKR|KHS|KHS1|MAPKKKK5	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAP4K5:GNF-7)	-
31379	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK14:GNF-7)	-
31381	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK7:GNF-7)	-
31383	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK8:GNF-7)	-
31385	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPK9:GNF-7)	-
31387	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31389	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113617	7867	-	MAPKAPK3	3PK|MAPKAP-K3|MAPKAP3|MAPKAPK-3|MK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK3:GNF-7)	-
31391	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119685	51701	-	NLK	-	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- NLK:GNF-7)	-
31393	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	127209	149420	RP11-96L14.4	PDIK1L	CLIK1L|STK35L2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- PDIK1L:GNF-7)	-
31395	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108480	2185	-	PTK2B	CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- PTK2B:GNF-7)	-
31397	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114274	8737	-	RIPK1	RIP|RIP1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RIPK1:GNF-7)	-
31399	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112109	6195	RP11-492M19.2	RPS6KA1	HU-1|MAPKAPK1A|RSK|RSK1|p90Rsk	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA1:GNF-7)	-
31401	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112111	6197	RP11-393H10.3	RPS6KA3	CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- RPS6KA3:GNF-7)	-
31403	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- SIK2:GNF-7)	-
31405	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- SIK3:GNF-7)	-
31407	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- STK35:GNF-7)	-
31409	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115485	10188	-	TNK2	ACK|ACK-1|ACK1|p21cdc42Hs	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- TNK2:GNF-7)	-
31411	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: DB1113 (VHL:VHL-1--- ULK1:GNF-7)	-
31416	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- AURKA:Ceritinib)	-
31420	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31428	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31442	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- GSK3B:Ceritinib)	-
31448	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
31450	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
31470	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide---AURKA:AT7519)	-
31482	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK4:AT7519)	-
31486	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CHEK1:AT7519)	-
31500	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- GSK3B:AT7519)	-
31510	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- PLK1:AT7519)	-
31523	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1---AAK1:Thienopyrimidines)	-
31525	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK1:Thienopyrimidines)	-
31527	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK16:Thienopyrimidines)	-
31529	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK2:Thienopyrimidines)	-
31531	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK4:Thienopyrimidines)	-
31533	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK6:Thienopyrimidines)	-
31535	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	136426	440275	-	EIF2AK4	GCN2|PVOD2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- EIF2AK4:Thienopyrimidines)	-
31537	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- GAK:Thienopyrimidines)	-
31539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- LATS1:Thienopyrimidines)	-
31541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- LIMK2:Thienopyrimidines)	-
31543	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111583	5597	-	MAPK6	ERK3|HsT17250|PRKM6|p97MAPK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MAPK6:Thienopyrimidines)	-
31545	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114120	8550	-	MAPKAPK5	MAPKAP-K5|MK-5|MK5|PRAK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MAPKAPK5:Thienopyrimidines)	-
31547	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MARK2:Thienopyrimidines)	-
31549	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MARK4:Thienopyrimidines)	-
31551	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109130	2872	-	MKNK2	GPRK7|MNK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- MKNK2:Thienopyrimidines)	-
31553	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- NEK9:Thienopyrimidines)	-
31555	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- RPS6KB1:Thienopyrimidines)	-
31557	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- SIK2:Thienopyrimidines)	-
31559	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- SNRK:Thienopyrimidines)	-
31561	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK17A:Thienopyrimidines)	-
31563	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK17B:Thienopyrimidines)	-
31565	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	126760	140901	-	STK35	CLIK1|STK35L1	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- STK35:Thienopyrimidines)	-
31567	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: RSS0680 (VHL:VHL-1--- WEE1:Thienopyrimidines)	-
31574	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- AURKA:TAE684)	-
31586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK2:TAE684)	-
31588	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK4:TAE684)	-
31592	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK6:TAE684)	-
31614	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- SRC:TAE684)	-
31620	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- AURKA:Thienopyrimidines)	-
31628	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
31630	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
31632	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- EIF2AK2:Thienopyrimidines)	-
31644	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK8:Thienopyrimidines)	-
31646	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- MAPK9:Thienopyrimidines)	-
31650	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- PLK4:Thienopyrimidines)	-
31665	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10070	Bivalent Ligand 280	DD-02-198|Bivalent_Ligand_280	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: DD-02-198 (VHL:VH032---MAPK14:AZ628)	-
31672	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide---CDK4:TAE684)	-
31674	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- AURKA:TAE684)	-
31682	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK6:TAE684)	-
31690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK2:TAE684)	-
31714	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide---AURKA:Dabrafenib)	-
31718	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK1:Dabrafenib)	-
31724	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK2:Dabrafenib)	-
31728	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK4:Dabrafenib)	-
31730	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK6:Dabrafenib)	-
31738	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- EIF2AK2:Dabrafenib)	-
31740	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- LIMK1:Dabrafenib)	-
31748	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- PLK1:Dabrafenib)	-
31750	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- PDK1:Dabrafenib)	-
31760	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- AURKA:PP58 (kinobeads) 212391-57-6)	-
31778	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- MAPK14:PP58 (kinobeads) 212391-57-6)	-
31782	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- PDK1:PP58 (kinobeads) 212391-57-6)	-
31788	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide--- SRC:PP58 (kinobeads) 212391-57-6)	-
31798	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- AURKA:TAE684)	-
31806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK2:TAE684)	-
31808	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK4:TAE684)	-
31812	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK6:TAE684)	-
31832	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide---CDK4:GNF-7)	-
31850	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- SRC:GNF-7)	-
31854	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide--- MAPK14:GNF-7)	-
31856	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10063	Bivalent Ligand 287	DB0663|Bivalent_Ligand_287	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0663 (CRBN:Thalidomide---a MAPK9:GNF-7)	-
31868	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- CDK4:GNF-7)	-
31878	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- LIMK1:GNF-7)	-
31880	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK8:GNF-7)	-
31882	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- MAPK9:GNF-7)	-
31886	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- PLK1:GNF-7)	-
31892	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10062	Bivalent Ligand 288	DB0661|Bivalent_Ligand_288	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0661 (CRBN:Thalidomide--- SRC:GNF-7)	-
31902	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- AURKA:MRT68921)	-
31932	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide---AURKA:Ceritinib)	-
31934	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK1:Ceritinib)	-
31942	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK2:Ceritinib)	-
31944	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK4:Ceritinib)	-
31948	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK6:Ceritinib)	-
31956	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK8:Ceritinib)	-
31958	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- MAPK9:Ceritinib)	-
31964	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- AURKA:TAE684)	-
31972	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK2:TAE684)	-
31992	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide---CDK4:Dinaciclib)	-
31998	111362	5347	-	PLK1	PLK|STPK13	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- PLK1:Dinaciclib)	-
32017	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide---AAK1:APY-24)	-
32019	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- AURKA:APY-24)	-
32021	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114646	9212	-	AURKB	AIK2|AIM-1|AIM1|ARK2|AurB|IPL1|PPP1R48|STK12|STK5|aurkb-sv1|aurkb-sv2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- AURKB:APY-24)	-
32023	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120735	55589	HRIHFB2017	BMP2K	BIKE	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- BMP2K:APY-24)	-
32025	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- CDK9:APY-24)	-
32027	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- EPHB2:APY-24)	-
32029	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109187	2932	-	GSK3B	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- GSK3B:APY-24)	-
32031	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109907	3702	-	ITK	EMT|LPFS1|LYK|PSCTK2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- ITK:APY-24)	-
32033	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- LATS1:APY-24)	-
32035	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111809	5871	-	MAP4K2	BL44|GCK|RAB8IP	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- MAP4K2:APY-24)	-
32037	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- NEK9:APY-24)	-
32039	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115586	10298	-	PAK4	-	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- PAK4:APY-24)	-
32041	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- PLK4:APY-24)	-
32043	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- STK17B:APY-24)	-
32056	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- GSK3B:not specified)	-
32076	112665	6789	-	STK4	KRS2|MST1|TIIAC|YSK3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- STK4:not specified)	-
32080	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- AURKA:Thienopyrimidines)	-
32084	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK4:Thienopyrimidines)	-
32086	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10086	Bivalent Ligand 295	RSS0628|Bivalent_Ligand_295	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0628 (CRBN:Thalidomide--- CDK6:Thienopyrimidines)	-
32103	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1---AAK1:MRT68921)	-
32105	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- GAK:MRT68921)	-
32107	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108326	2011	-	MARK2	EMK-1|EMK1|PAR-1|Par-1b|Par1b	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK2:MRT68921)	-
32109	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110310	4140	-	MARK3	CTAK1|KP78|PAR1A|Par-1a	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK3:MRT68921)	-
32111	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- MARK4:MRT68921)	-
32113	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- RPS6KB1:MRT68921)	-
32115	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SIK2:MRT68921)	-
32117	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SIK3:MRT68921)	-
32119	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- SNRK:MRT68921)	-
32121	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- STK17A:MRT68921)	-
32123	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- STK17B:MRT68921)	-
32125	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113996	8408	-	ULK1	ATG1|ATG1A|UNC51|Unc51.1|hATG1	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- ULK1:MRT68921)	-
32127	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10087	Bivalent Ligand 296	BSJ-05-026|Bivalent_Ligand_296	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: BSJ-05-026 (VHL:VHL-1--- WEE1:MRT68921)	-
32130	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide---AURKA:Ceritinib)	-
32134	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
32136	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
32140	111585	5599	-	MAPK8	JNK|JNK-46|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1|SAPK1c	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK8:Ceritinib)	-
32142	111587	5601	-	MAPK9	JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- MAPK9:Ceritinib)	-
32144	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- PTK2:Ceritinib)	-
32158	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- AURKA:TX1-85-1)	-
32172	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- LIMK1:TX1-85-1)	-
32176	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide--- SRC:TX1-85-1)	-
32177	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1---AAK1:TG101209)	-
32179	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111154	5127	-	CDK16	PCTAIRE|PCTAIRE1|PCTGAIRE|PCTK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- CDK16:TG101209)	-
32181	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- WEE1:TG101209)	-
32183	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- GAK:TG101209)	-
32185	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	121760	57787	-	MARK4	MARK4L|MARK4S|MARKL1|MARKL1L|PAR-1D	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- MARK4:TG101209)	-
32187	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124876	91754	-	NEK9	NERCC|NERCC1|Nek8	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- NEK9:TG101209)	-
32189	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112112	6198	-	RPS6KB1	PS6K|S6K|S6K-beta-1|S6K1|STK14A|p70 S6KA|p70(S6K)-alpha|p70-S6K|p70-alpha	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- RPS6KB1:TG101209)	-
32191	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SIK2:TG101209)	-
32193	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116963	23387	L19	SIK3	QSK|SIK-3	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SIK3:TG101209)	-
32195	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120211	54861	-	SNRK	HSNFRK	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- SNRK:TG101209)	-
32197	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- STK17A:TG101209)	-
32199	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10084	Bivalent Ligand 299	JWG-123|Bivalent_Ligand_299	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114684	9262	-	STK17B	DRAK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-123 (VHL:VHL-1--- STK17B:TG101209)	-
32218	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- LIMK1:TX1-85-1)	-
32222	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide--- SRC:TX1-85-1)	-
32232	109863	3654	-	IRAK1	IRAK|pelle	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- IRAK1:Quizartinib)	-
32238	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- MAPK14:Quizartinib)	-
32242	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10022	Bivalent Ligand 301	TL13-150|Bivalent_Ligand_301	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-150 (CRBN:pomalidomide--- SRC :Quizartinib)	-
32250	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- GSK3B:not specified)	-
32260	112665	6789	-	STK4	KRS2|MST1|TIIAC|YSK3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- STK4:not specified)	-
32268	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10020	Bivalent Ligand 303	ZNL-02-096|Bivalent_Ligand_303	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ZNL-02-096 (CRBN:pomalidomide--- PDK1:Adavosertib)	-
32284	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10017	Bivalent Ligand 304	DB118430|Bivalent_Ligand_304	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB118430 (IAP:LCL161 derivative--- CDK4:GNF-7)	-
32298	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide---AURKA:PND-1186)	-
32304	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- MAPK7:PND-1186)	-
32318	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK4:Palbociclib)	-
32320	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32324	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8516	Bivalent ligand 76	protac 6|BSJ-03-123|Bivalent_ligand_76	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-123 (CRBN:pomalidomide--- PDK1:Palbociclib)	-
32334	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- AURKA:kinobeads)	-
32338	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- CDK6:kinobeads)	-
32356	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- GSK3B:AT7519)	-
32362	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide---AURKA:PND-1186)	-
32378	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK4:Ribociclib)	-
32380	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- CDK6:Ribociclib)	-
32384	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10014	Bivalent Ligand 309	BSJ-04-132|Bivalent_Ligand_309	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-132 (CRBN:Thalidomide--- PDK1:Ribociclib)	-
32400	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9990	Bivalent Ligand 310	DD-03-119|Bivalent_Ligand_310	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-119 (CRBN:pomalidomide--- SRC:Ibrutinib)	-
32416	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide---AKT1:Ipatasertib)	-
32422	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9992	Bivalent Ligand 312	INY-03-041-01|Bivalent_Ligand_312	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-03-041-01 (CRBN:lenalidomide--- CDK4:Ipatasertib)	-
32428	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide---CDK4:Ponatininb)	-
32430	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- LIMK1:Ponatininb)	-
32434	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9991	Bivalent Ligand 313	TL13-178|Bivalent_Ligand_313	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-178 (CRBN:pomalidomide--- MAPK14:Ponatininb)	-
32438	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9994	Bivalent Ligand 314	ZNL-03-127|Bivalent_Ligand_314	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ZNL-03-127 (CRBN:pomalidomide--- LIMK1:XMD8-87)	-
32448	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- LIMK1:Dabrafenib)	-
32450	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9993	Bivalent Ligand 315	DD-03-107|Bivalent_Ligand_315	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-107 (CRBN:lenalidomide--- PDK1:Dabrafenib)	-
32456	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9996	Bivalent Ligand 316	INY-02-164|Bivalent_Ligand_316	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-02-164 (CRBN:Thalidomide---AKT1:Ipatasertib)	-
32466	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9995	Bivalent Ligand 317	JWG-118|Bivalent_Ligand_317	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JWG-118 (CRBN:Thalidomide--- AURKA:TG101209)	-
32474	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9987	Bivalent Ligand 318	SB1-G-190|Bivalent_Ligand_318	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-190 (CRBN:Thalidomide--- AURKA:APY-24)	-
32480	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-204 (CRBN:thalidomide---CDK4:Palbociclib)	-
32482	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- CDK6:Palbociclib)	-
32484	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	9986	Bivalent Ligand 319	BSJ-03-204|Bivalent_Ligand_319	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-03-204 (CRBN:Thalidomide--- PDK1:Palbociclib)	-
32495	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106545	27	RP11-177A2.3	ABL2	ABLL|ARG	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1---ABL2:not specified)	-
32497	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108362	2048	-	EPHB2	CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- EPHB2:not specified)	-
32499	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116840	23235	-	SIK2	LOH11CR1I|QIK|SNF1LK2	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- SIK2:not specified)	-
32501	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10139	Bivalent Ligand 321	JWG-148|Bivalent_Ligand_321	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	target	Standardized BVL Name: JWG-148 (VHL:VHL-1--- TYK2:not specified)	-
32503	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111155	5128	-	CDK17	PCTAIRE2|PCTK2	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- CDK17:Dabrafenib)	-
32505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- LIMK1:Dabrafenib)	-
32507	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10140	Bivalent Ligand 322	DD-03-156|Bivalent_Ligand_322	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110173	3985	-	LIMK2	-	9606	Homo sapiens	target	Standardized BVL Name: DD-03-156 (VHL:VHL-1--- LIMK2:Dabrafenib)	-
32510	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32512	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10141	Bivalent Ligand 323	BSJ-01-147|Bivalent_Ligand_323	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-01-147 (CRBN:pomalidomide--- CDK6:Palbociclib)	-
32516	111189	5163	-	PDK1	-	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10134	Bivalent Ligand 324	INY-01-140-1|Bivalent_Ligand_324	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: INY-01-140-1 (CRBN:Thalidomide---PDK1:MK-2206)	-
32522	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10135	Bivalent Ligand 325	TL13-12|Bivalent_Ligand_325	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-12 (CRBN:pomalidomide---AURKA:TAE684)	-
32530	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10136	Bivalent Ligand 326	JWG-120|Bivalent_Ligand_326	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JWG-120 (CRBN:Thalidomide--- AURKA:not specified)	-
32531	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10137	Bivalent Ligand 327	INY-04-125-01|Bivalent_Ligand_327	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114563	9113	-	LATS1	WARTS|wts	9606	Homo sapiens	target	Standardized BVL Name: INY-04-125-01 (VHL:VHL-1--- LATS1:MK-2206)	-
32533	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10137	Bivalent Ligand 327	INY-04-125-01|Bivalent_Ligand_327	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114685	9263	-	STK17A	DRAK1	9606	Homo sapiens	target	Standardized BVL Name: INY-04-125-01 (VHL:VHL-1--- STK17A:MK-2206)	-
32535	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10142	Bivalent Ligand 328	JWG-122|Bivalent_Ligand_328	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116520	22848	RP11-427H3.3	AAK1	-	9606	Homo sapiens	target	Standardized BVL Name: JWG-122 (VHL:VHL-1---AAK1:TG101209)	-
32537	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10142	Bivalent Ligand 328	JWG-122|Bivalent_Ligand_328	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108853	2580	-	GAK	DNAJ26|DNAJC26	9606	Homo sapiens	target	Standardized BVL Name: JWG-122 (VHL:VHL-1--- GAK:TG101209)	-
32539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10143	Bivalent Ligand 329	ZZ-1-31B|Bivalent_Ligand_329	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	target	Standardized BVL Name: ZZ-1-31B (VHL:VH032---CDK9:SNS032)	-
32541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Donovan KA (2020)	33275901	231643	10143	Bivalent Ligand 329	ZZ-1-31B|Bivalent_Ligand_329	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107606	1195	-	CLK1	CLK|CLK/STY|STY	9606	Homo sapiens	target	Standardized BVL Name: ZZ-1-31B (VHL:VH032---CLK1:SNS032)	-
32546	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10117	Bivalent Ligand 330	TL13-112|Bivalent_Ligand_330	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-112 (CRBN:pomalidomide--- PTK2:TAE684)	-
32550	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK4:Palbociclib)	-
32552	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10116	Bivalent Ligand 331	YKL-06-102|Bivalent_Ligand_331	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YKL-06-102 (CRBN:pomalidomide---CDK6:Palbociclib)	-
32555	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xu C (2021)	34469831	232212	10115	Bivalent Ligand 332	Bivalent_Ligand_332	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120250	54904	DC28	WHSC1L1	NSD3|pp14328	9606	Homo sapiens	target	Standardized BVL Name: MS9715 (VHL:VHL1-Me---NSD3:BI-9321)	-
32559	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yan S (2021)	34093856	232273	10110	Bivalent ligand 334	dCeMM4|Bivalent_ligand_334	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	110359	4194	RP11-430C7.1	MDM4	HDMX|MDMX|MRP1	9606	Homo sapiens	target	Standardized BVL Name: Nano-MP@PSI (VHL:Nano-MP@PSI---MDMX:Nano-MP@PSI)	-
32562	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Qu X (2021)	33773286	232265	10113	Bivalent Ligand 335	Bivalent_Ligand_335	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS125 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32564	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Qu X (2021)	33773286	232265	10112	Bivalent Ligand 336	Bivalent_Ligand_336	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS126 (CRBN:pomalidomide---EGFR(L858R+T790M mutant):SIAIS092)	-
32566	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu R (2021)	34700270	232271	10111	Bivalent Ligand 337	Bivalent_Ligand_337	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WWL0245 (CRBN:thalidomide---BRD4:WNY0824)	-
32571	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---SMARCA2:AU-15139)	-
32573	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---SMARCA4:AU-15139)	-
32575	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao L (2021)	34937944	232716	10098	Bivalent Ligand 340	AU-15330|Bivalent_Ligand_340	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120490	55193	-	PBRM1	BAF180|PB1	9606	Homo sapiens	target	Standardized BVL Name: AU-15330 (VHL:VL285---PBRM1:AU-15139)	-
32577	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Huber ME (2021)	34936714	232717	10099	Bivalent Ligand 341	13|Bivalent_Ligand_341	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116017	10803	-	CCR9	CC-CKR-9|CDw199|GPR-9-6|GPR28	9606	Homo sapiens	target	Standardized BVL Name: 13 (VHL:(S,R,S)-AHPC---CCR9:vercirnon)	-
32579	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang C (2021)	34927316	232727	10096	Bivalent Ligand 342	SPNCOX|Bivalent_Ligand_342	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	111714	5742	RP11-542K23.6	PTGS1	COX1|COX3|PCOX1|PES-1|PGG/HS|PGHS-1|PGHS1|PHS1|PTGHS	9606	Homo sapiens	target	Standardized BVL Name: SPNCOX (VHL:GSGSALAPYIP---PTGS1:indomethacin)	-
32581	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang C (2021)	34927316	232727	10096	Bivalent Ligand 342	SPNCOX|Bivalent_Ligand_342	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	111715	5743	-	PTGS2	COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2	9606	Homo sapiens	target	Standardized BVL Name: SPNCOX (VHL:GSGSALAPYIP---PTGS2:indomethacin)	-
32583	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lu X (2021)	34916494	232728	10097	Bivalent Ligand 343	XL5-VHL-2|Bivalent_Ligand_343	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116235	11047	-	ADRM1	ARM-1|ARM1|GP110	9606	Homo sapiens	target	Standardized BVL Name: XL5-VHL-2 (VHL:VHL ligand---ADRM1:XL5)	-
32586	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Lu Y (2021)	34885822	232750	10102	Bivalent Ligand 344	21a|Bivalent_Ligand_344	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 21a(CRBN:lenalidomide---HDAC6:benzamide)	-
32588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32593	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2021)	34100597	232747	10100	Bivalent Ligand 346	Bivalent_Ligand_346	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111902	5970	-	RELA	NFKB3|p65	9606	Homo sapiens	target	Standardized BVL Name: NF-kB-PROTAC (dNF-kB)(VHL:VHLL-X-BCN---RELA:N3-ODN)	-
32595	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu J (2021)	34100597	232747	10101	Bivalent Ligand 347	Bivalent_Ligand_347	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108201	1869	-	E2F1	E2F-1|RBAP1|RBBP3|RBP3	9606	Homo sapiens	target	Standardized BVL Name: E2F-PROTAC (dE2F) (VHL:VHLL-X-BCN---E2F1:N3-ODN)	-
32598	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Cao Z (2021)	34860497	239580	10105	Bivalent Ligand 348	14a|Bivalent_Ligand_348	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 14a (CRBN:pomalidomide---HDAC6:indirubin)	-
32599	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT1:GDC-0068)	-
32601	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT2:GDC-0068)	-
32603	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34855399	232882	10106	Bivalent Ligand 349	MS98|Bivalent_Ligand_349	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: MS98 (VHL:VHL-2---AKT3:GDC-0068)	-
32606	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	degradation	target	Yu X (2021)	34855399	232882	10078	Bivalent Ligand 350	MS170|Bivalent_Ligand_350	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS170 (CRBN:pomalidomide---AKT1:GDC-0068)	-
32613	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10080	Bivalent Ligand 352	ORN3P1|Bivalent_Ligand_352	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN3P1 (VHL:HIF1a peptide---LIN28A:AGGAGAU)	-
32615	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10079	Bivalent Ligand 353	ORN7P1|Bivalent_Ligand_353	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN7P1 (VHL:HIF1a peptide---LIN28A:AGGAGAUAACU)	-
32617	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10074	Bivalent Ligand 354	ORN9P1|Bivalent_Ligand_354	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120107	54715	-	RBFOX1	2BP1|A2BP1|FOX-1|FOX1|HRNBP1	9606	Homo sapiens	target	Standardized BVL Name: ORN9P1 (VHL:HIF1a peptide---RBFOX1:UGCAUGU)	-
32619	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ghidini A (2021)	33108679	233302	10073	Bivalent Ligand 355	ORN3VH032|Bivalent_Ligand_355	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122842	79727	-	LIN28A	CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A	9606	Homo sapiens	target	Standardized BVL Name: ORN3VH032 (VHL:VH032---LIN28A:AGGAGAU)	-
32625	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lv D (2021)	34824248	234973	10072	Bivalent Ligand 358	753b|Bivalent_Ligand_358	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 753b (VHL:VHL ligand---BCL2L1:ABT263)	-
32627	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lv D (2021)	34824248	234973	10072	Bivalent Ligand 358	753b|Bivalent_Ligand_358	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	target	Standardized BVL Name: 753b (VHL:VHL ligand---BCL2:ABT263)	-
32634	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Eron SJ (2021)	34582690	235023	10047	Bivalent Ligand 361	CFT-1297|Bivalent_Ligand_361	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CFT-1297 (CRBN:thalidomide---BRD4:triazoloazepine ligand)	-
32635	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roberts BL (2020)	32255606	235043	10048	Bivalent Ligand 362	AM-A3|Bivalent_Ligand_362	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: AM-A3 (VHL:VHL ligand---ER:raloxifene)	-
32638	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	He K (2020)	32317208	235047	10049	Bivalent Ligand 363	PROTAC 16c|Bivalent_Ligand_363	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 16c (CRBN:lenalidomide---EGFR:osimertinib)	-
32639	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Law RP (2021)	34416073	239581	10050	Bivalent Ligand 364	GSK215|Bivalent_Ligand_364	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	target	Standardized BVL Name: GSK215 (VHL:VHL-021 ---PTK2:VS-4718)	-
32642	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Lin X (2020)	32829249	223472	10051	Bivalent Ligand 365	ARV-471|Bivalent_Ligand_365	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ARV-471(CRBN:lenalidomide---ESR1:Lasofoxifene)	-
32643	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10052	Bivalent Ligand 367	AGB1|Bivalent_Ligand_367	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB1 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32645	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10044	Bivalent Ligand 368	AGB2|Bivalent_Ligand_368	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB2 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32647	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond AG (2021)	34652918	235084	10045	Bivalent Ligand 369	AGB3|Bivalent_Ligand_369	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: AGB3 (VHL:VH032---BromoTag-BRD2:ET-JQ1-OH)	-
32655	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC1:CI-994)	-
32657	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC2:CI-994)	-
32659	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10025	Bivalent Ligand 373	JPS014|Bivalent_Ligand_373	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS014 (VHL:VHL ligand---HDAC3:CI-994)	-
32661	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC1:CI-994)	-
32663	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC2:CI-994)	-
32665	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10032	Bivalent Ligand 374	JPS016|Bivalent_Ligand_374	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS016 (VHL:VHL ligand---HDAC3:CI-994)	-
32667	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Smalley JP (2022)	35293758	235205	10031	Bivalent Ligand 375	JPS036|Bivalent_Ligand_375	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS036 (VHL:fluorinated cyclopropane VHL analogue---HDAC3:CI-994)	-
32672	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 5 (CRBN:pomalidomide---JAK2:ruxolitinib)	-
32674	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 6 (CRBN:pomalidomide---JAK2:baricitinib)	-
32676	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 7 (CRBN:pomalidomide---JAK2:ruxolitinib N-propyl analog)	-
32678	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10007	Bivalent Ligand 380	compound 8|Bivalent_Ligand_380	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 8 (CRBN:thalidomide---JAK2:baricitinib)	-
32680	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 5 (CRBN:pomalidomide---JAK1:ruxolitinib)	-
32688	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10029	Bivalent Ligand 377	compound 5|Bivalent_Ligand_377	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 5 (CRBN:pomalidomide---TYK2:ruxolitinib)	-
32690	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 6 (CRBN:pomalidomide---JAK1:baricitinib)	-
32698	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10024	Bivalent Ligand 378	compound 6|Bivalent_Ligand_378	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 6 (CRBN:pomalidomide---TYK2:baricitinib)	-
32700	109919	3716	-	JAK1	JAK1A|JAK1B|JTK3	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 7 (CRBN:pomalidomide---JAK1:ruxolitinib N-propyl analog)	-
32708	113148	7297	-	TYK2	IMD35|JTK1	9606	Homo sapiens	degradation	target	Chang Y (2021)	34110416	235255	10023	Bivalent Ligand 379	compound 7|Bivalent_Ligand_379	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 7 (CRBN:pomalidomide---TYK2:ruxolitinib N-propyl analog)	-
32710	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Adhikari B (2020)	32989298	235317	10007	Bivalent Ligand 380	compound 8|Bivalent_Ligand_380	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JB158 (CRBN:thalidomide---AURKA:alisertib)	-
32712	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Adhikari B (2020)	32989298	235317	10008	Bivalent Ligand 381	JB170|Bivalent_Ligand_381	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JB170 (CRBN:thalidomide---AURKA:alisertib)	-
32713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Shen Y (2020)	32787082	235326	10118	Bivalent Ligand 382	compound 15|Bivalent_Ligand_382	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115688	10419	-	PRMT5	HRMT1L5|IBP72|JBP1|SKB1|SKB1Hs	9606	Homo sapiens	target	Standardized BVL Name: compound 15 (VHL:VHL-2---PRMT5:EPZ015666)	-
32715	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2019)	30990042	235710	10133	Bivalent Ligand 383	ERD-308|Bivalent_Ligand_383	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ERD-308 (VHL:compound 11---ESR1:raloxifene)	-
32718	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK1:TL13-87)	-
32720	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
32722	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK4:TL13-87)	-
32726	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK6:TL13-87)	-
32750	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Wang J (2022)	35210568	236436	9999	Bivalent ligand 384	MS177|Bivalent_ligand_384	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS177 (CRBN:pomalidomide --- EZH2:C24)	-
32751	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EZH2:EED226)	-
32753	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- EED:EED226)	-
32755	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Potjewyd F (2020)	31831267	236457	10000	Bivalent ligand 385	UNC6852|Bivalent_ligand_385	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC6852 (VHL:VH032-amine --- SUZ12:EED226)	-
32758	108347	2033	RP1-85F18.1	EP300	KAT3B|RSTS2|p300	9606	Homo sapiens	degradation	target	Durbin AD (2022)	34772733	236045	9997	Bivalent ligand 386	JQAD1|Bivalent_ligand_386	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JQAD1 (CRBN:pomalidomide --- EP300:A485)	-
32772	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Wei J (2021)	34520194	236464	10082	Bivalent ligand 389	MS83|Bivalent_ligand_389	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS83 (KEAP1:KEAP1-L --- BRD4:unspecified)	-
32779	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Salami J (2018)	30271980	239582	10147	Bivalent ligand 392	ARCC-4|Bivalent_ligand_392	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ARCC-4 (VHL:HIF-1alpha hydroxyproline derived small molecule --- AR:enzalutamide)	-
32794	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Cotton AD (2021)	33395526	231300	10152	Bivalent ligand 399	AC-1|Bivalent_ligand_399	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: AC-1 (RNF43:RNF43 ab, R0 clone --- CD274:atezolizumab)	-
32796	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10123	Bivalent ligand 400	R3/atz|Bivalent_ligand_400	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R3/atz (RNF43:RNF43 ab, R3 clone --- CD274:atezolizumab)	-
32798	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10122	Bivalent ligand 401	R6/atz|Bivalent_ligand_401	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R6/atz (RNF43:RNF43 ab, R6 clone --- CD274:atezolizumab)	-
32800	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10125	Bivalent ligand 402	R0/ctx|Bivalent_ligand_402	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/ctx (RNF43:RNF43 ab, R0 clone --- EGFR:cetuximab)	-
32802	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10124	Bivalent ligand 403	R0/matu|Bivalent_ligand_403	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/matu (RNF43:RNF43 ab, R0 clone --- EGFR:matuzumab)	-
32804	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10127	Bivalent ligand 404	R0/neci|Bivalent_ligand_404	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/neci (RNF43:RNF43 ab, R0 clone --- EGFR:necitumumab)	-
32806	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10126	Bivalent ligand 405	R0/pani|Bivalent_ligand_405	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R0/pani (RNF43:RNF43 ab, R0 clone --- EGFR:panitumumab)	-
32808	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10129	Bivalent ligand 406	R3/ctx|Bivalent_ligand_406	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	120241	54894	-	RNF43	RNF124|URCC	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: R3/ctx  (RNF43:RNF43 ab, R3 clone --- EGFR:cetuximab)	-
32810	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10128	Bivalent ligand 407	Z18/atz|Bivalent_ligand_407	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Z18/atz (ZNRF3:Z18 --- CD274:atezolizumab)	-
32812	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Gosavi PM (2022)	35505873	237057	10131	Bivalent ligand 408	Z18/ctx|Bivalent_ligand_408	-	BIOGRID	-	-	antibody	-	-	BIOGRID	AbTAC	Antibody-based PROTACs, in which bispecific IgGs bind to two proteins simultaneously, an E3 and POI; target degraded via UPS	123905	84133	hCG_40978	ZNRF3	BK747E2.3|RNF203	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Z18/ctx (ZNRF3:Z18 --- EGFR:cetuximab)	-
32822	109920	3717	-	JAK2	JTK10|THCYT3	9606	Homo sapiens	degradation	target	Alcock LJ (2022)	35300081	239585	10107	Bivalent ligand 413	PROTAC11/SJ10542|Bivalent_ligand_413	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC11/SJ10542 (CRBN:phenyl glutarimide --- JAK2:baricitinib)	-
32825	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bond MJ (2020)	32875077	239586	10095	Bivalent ligand 414	LC-2|Bivalent_ligand_414	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: LC-2 (VHL:HIF-1alpha hydroxyproline derived small molecule --- KRAS-G12c:MRTX849)	-
32827	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Guo L (2022)	35397401	239587	10132	Bivalent ligand 415	LG-AR-14|Bivalent_ligand_415	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: LG-AR-14 (VHL:VHL ligand --- AR:AR ligand 3)	-
32829	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Guo L (2022)	35397401	239587	9988	Bivalent ligand 416	LG-BRD-12|Bivalent_ligand_416	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: LG-BRD-12 (VHL:VHL ligand --- BRD4:JQ1)	-
32831	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32834	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	degradation	target	Yu X (2022)	35119851	239588	10154	Bivalent ligand 418	compound 35|Bivalent_ligand_418	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 35 (CRBN:pomalidomide --- AKT:AZD5363)	-
32835	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106711	208	-	AKT2	HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32839	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2022)	35119851	239588	10043	Bivalent ligand 417	compound 20|Bivalent_ligand_417	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115318	10000	-	AKT3	MPPH|MPPH2|PKB-GAMMA|PKBG|PRKBG|RAC-PK-gamma|RAC-gamma|STK-2	9606	Homo sapiens	target	Standardized BVL Name: compound 20 (VHL:VHL-1 --- AKT:AZD5363)	-
32845	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Pillow TH (2020)	31674143	239590	10060	Bivalent ligand 420	GNE-987|Bivalent_ligand_420	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: GNE-987 ( VHL:VHL-1 --- BRD4:BET inhibitor)	-
32847	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang H (2022)	35344835	239591	10059	Bivalent ligand 421	HL-8|Bivalent_ligand_421	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111308	5290	-	PIK3CA	CLOVE|CWS5|MCAP|MCM|MCMTC|PI3K|p110-alpha	9606	Homo sapiens	target	Standardized BVL Name: HL-8(VHL:VHL ligand --- PIK3CA:compound 15a)	-
32849	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10058	Bivalent ligand 422	WJ638|Bivalent_ligand_422	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: WJ638 (VHL: VH032 --- VHL: VH032)	-
32851	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10057	Bivalent ligand 423	WJ051|Bivalent_ligand_423	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ051  (VHL: VH032 --- BRD4:JQ1)	-
32853	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10056	Bivalent ligand 424	WJ281|Bivalent_ligand_424	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ281  (VHL: VH032 --- BRD4:JQ1)	-
32855	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2022)	35802347	238278	10055	Bivalent ligand 425	WJ287|Bivalent_ligand_425	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: WJ287  (VHL: VH032 --- BRD4:JQ1)	-
32873	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Tao Y (2022)	36170674	241674	10370	Bivalent ligand 430	YT117R|Bivalent_ligand_430	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YT117R (DCAF1:MY-1B ---BRD4:JQ1)	-
32875	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Henning NJ (2022)	34994556	235307	10371	Bivalent ligand 431	NJH-1-106|Bivalent_ligand_431	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NJH-1-106 (FEM1B:EN106 ---BRD4:JQ1)	-
32879	110694	4609	-	MYC	MRTL|MYCC|bHLHe39|c-Myc	9606	Homo sapiens	degradation	target	Lier S (2022)	34838332	242581	10373	Bivalent ligand 433	MDEG-541|Bivalent_ligand_433	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MDEG-541  (CRBN:thalidomide --- MYC:10058-F4)	-
32880	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng KW (2021)	33976200	242625	10366	Bivalent ligand 434	VHL-12VC1.2 fusion|Bivalent_ligand_434	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL12VC1.2 fusion (VHL --- KRAS(G12C):12VC1.2)	-
32882	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng KW (2021)	33976200	242625	10367	Bivalent ligand 435	VHL-12VC1.1 fusion|Bivalent_ligand_435	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL12VC1.1 fusion (VHL --- KRAS(G12C):12VC1.1)	-
32884	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10368	Bivalent ligand 436	VHL-aGFP16 AdPROM|Bivalent_ligand_436	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-aGFP16 AdPROM (VHL:aGFP16 --- KRAS:GFP)	-
32886	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10369	Bivalent ligand 437	VHL-aHRAS AdPROM|Bivalent_ligand_437	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-aHRAS AdPROM (VHL --- KRAS:aHRAS)	-
32888	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Roeth S (2020)	32668202	242881	10369	Bivalent ligand 437	VHL-aHRAS AdPROM|Bivalent_ligand_437	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: VHL-aHRAS AdPROM (VHL --- HRAS:aHRAS)	-
32893	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- HRAS:iDAB RAS)	-
32899	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- HRAS:iDAB RAS)	-
32902	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10402	Bivalent ligand 440	VHL-iDAb RAS|Bivalent_ligand_440	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-iDAb RAS (VHL --- KRAS:iDAB RAS)	-
32904	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10402	Bivalent ligand 440	VHL-iDAb RAS|Bivalent_ligand_440	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: VHL-iDAb RAS (VHL --- NRAS:iDAB RAS)	-
32906	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10401	Bivalent ligand 441	VHL-DP KRAS|Bivalent_ligand_441	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: VHL-DP KRAS (VHL --- KRAS:DARPin K19)	-
32925	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	degradation	target	Lim S (2021)	33655066	242886	10408	Bivalent ligand 449	K27-SPOP|Bivalent_ligand_449	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: K27-SPOP (SPOP --- HRAS:DARPin K27)	-
32930	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10374	Bivalent ligand 451	K27-VHL|Bivalent_ligand_451	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: K27-VHL (VHL --- KRAS:DARPin K27)	-
32939	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK6:palbociclib)	-
32941	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10377	Bivalent ligand 456	SAB355|Bivalent_ligand_456	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB355 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32943	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10382	Bivalent ligand 457	CST837|Bivalent_ligand_457	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CST837 (CRBN:thalidomide --- CDK6:palbociclib)	-
32944	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bricelj A (2021)	34795861	243021	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32947	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Bricelj A (2021)	34795861	243021	10389	Bivalent ligand 455	SAB401|Bivalent_ligand_455	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SAB401 (CRBN:thalidomide --- CDK4:palbociclib)	-
32955	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Qu L (2021)	34649182	243029	10381	Bivalent ligand 505	PT-65|Bivalent_ligand_505	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PT-65 (CRBN:pomalidomide --- GSK3B:AZD2858)	-
32956	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10361	Bivalent ligand 459	PROTAC 34|Bivalent_ligand_459	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 34 (VHL:modified VH298 --- CDK6:palbociclib)	-
32958	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10360	Bivalent ligand 458	CST651/PROTAC 27|Bivalent_ligand_458	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: CST651/PROTAC 27 (VHL:modified VH298 --- CDK6:palbociclib)	-
32961	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10418	Bivalent ligand 460	PROTAC 11|Bivalent_ligand_460	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 11 (CRBN:pomalidomide --- CDK6:palbociclib)	-
32962	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK6:palbociclib)	-
32964	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP1:IAP ligand --- CDK4:palbociclib)	-
32966	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK4:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK4:palbociclib)	-
32969	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Steinebach C (2020)	33133483	244369	10415	Bivalent ligand 461	PROTAC 35|Bivalent_ligand_461	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 35 (cIAP2:IAP ligand --- CDK6:palbociclib)|Standardized BVL Name: PROTAC 35 (XIAP:IAP ligand --- CDK6:palbociclib)	-
32991	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao M (2021)	33676183	232098	10081	Bivalent ligand 388	CC-885|Bivalent_ligand_388	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CC-885 (CRBN:CC-885 --- CDK4:CC-885)	-
33021	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10410	Bivalent ligand 473	p53-DUBTACs #6|Bivalent_ligand_473	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: p53-DUBTACs #6 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33023	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10428	Bivalent ligand 474	p53-DUBTACs #7|Bivalent_ligand_474	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: p53-DUBTACs #7 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33025	109869	3661	-	IRF3	-	9606	Homo sapiens	deubiquitination	target	Liu J (2022)	35786952	245265	10417	Bivalent ligand 475	IRF-DUBTAC #7|Bivalent_ligand_475	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	recruited deubiquitinase	Standardized BVL Name: IRF-DUBTAC #7 (OTUB1:DUBL-X-BCN --- IRF3:N3-IRF3-ODN)	-
33029	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Shergalis AG (2023)	36656921	245121	10364	Bivalent ligand 476	1a|Bivalent_ligand_476	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 1a (DCAF16:1a---BRD4:1a)	-
33045	108202	1870	-	E2F2	E2F-2	9606	Homo sapiens	degradation	target	Liu TT (2022)	36375317	244515	10412	Bivalent ligand 482	bufalin|Bivalent_ligand_482	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	123322	80829	FKSG11	ZFP91	DMS-8|DSM-8|PZF|ZFP-91|ZNF757	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: bufalin (ZFP91:bufalin---E2F2:bufalin)	-
33047	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Su W (2023)	36647763	245466	10388	Bivalent ligand 483	CDTAC CDTAC PD-L1:CRBN|Bivalent_ligand_483	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CDTAC CDTAC PD-L1:CRBN (CRBN:thalidomide---CD274:BMS-1166)	-
33048	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang L (2022)	36250201	241369	10391	Bivalent ligand 484	ZL216|Bivalent_ligand_484	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110771	4691	-	NCL	C23	9606	Homo sapiens	target	Standardized BVL Name: ZL216 (VHL:AHPC ---NCL:AS1411)	-
33050	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Miao J (2023)	37836790	246251	10390	Bivalent ligand 485	P9|Bivalent_ligand_485	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111745	5781	-	PTPN11	BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2	9606	Homo sapiens	target	Standardized BVL Name: P9 (VHL:VHL-2 --- PTPN11:compound 4)	-
33052	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	antiviral	recruited e3 ligase	Desantis J (2021)	34534839	232373	10393	Bivalent ligand 486	PROTAC 3 anti-viral|Bivalent_ligand_486	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123135	80142	RP11-395P17.2	PTGES2	C9orf15|GBF-1|GBF1|PGES2|mPGES-2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 3 anti-viral (VHL: HIF-1alpha hydroxyproline derived small molecule---PTGES2:indomethacin; Coronavirus Project)	-
33054	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	antiviral	recruited e3 ligase	Desantis J (2021)	34534839	232373	10392	Bivalent ligand 487	PROTAC 5 anti-viral|Bivalent_ligand_487	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	123135	80142	RP11-395P17.2	PTGES2	C9orf15|GBF-1|GBF1|PGES2|mPGES-2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5 anti-viral (VHL: HIF-1alpha hydroxyproline derived small molecule---PTGES2:indomethacin; Coronavirus Project)	-
33062	112615	6737	-	TRIM21	RNF81|RO52|Ro/SSA|SSA|SSA1	9606	Homo sapiens	antiviral	recruited e3 ligase	Chatterjee P (2020)	33230174	239810	10425	Bivalent ligand 491	23-mer|Bivalent_ligand_491	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	4383848	43740568	GU280_gp02	S	spike|SARS-CoV2 S|SARS-CoV2 spike|S protein|surface|SARS-CoV-2 spike|SARS-CoV-2 S|SPIKE_SARS2|PRO_0000449646	2697049	Severe acute respiratory syndrome coronavirus 2	target	The authors fused the RBD-binding proteins to the CHIPTPR modified E3 ubiquitin ligase domain to prevent circumvent the need to express Trim21 in trans|Standardized BVL Name: 23-mer (A2N)-CHIPTPR (TRIM21:NA --- S RBD domain: sACE2 derived 23-mer (A2N) peptide; Coronavirus Project; Target UniProt ID PRO_0000449646 (S))	-
33066	112615	6737	-	TRIM21	RNF81|RO52|Ro/SSA|SSA|SSA1	9606	Homo sapiens	degradation 	recruited e3 ligase	Fletcher A (2023)	37925433	246254	10427	Bivalent ligand 493	T21RBCC-VHHHuR|Bivalent_ligand_493	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	108309	1994	-	ELAVL1	ELAV1|HUR|Hua|MelG	9606	Homo sapiens	target	Standardized BVL Name: T21RBCC-VHHHuR (TRIM21:NA--- ELAVL1:VHH ab)	-
33068	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10424	Bivalent ligand 494	CIP-1|Bivalent_ligand_494	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-1 (VHL:MZ1---BRD4:BB3-114)	-
33070	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10357	Bivalent ligand 495	CIP-3|Bivalent_ligand_495	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-3 (VHL:MZ1---BRD4:BB2-109)	-
33072	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10422	Bivalent ligand 496	CIP-4|Bivalent_ligand_496	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: CIP-4 (VHL:MZ1---BRD4:BB2-109)	-
33074	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Mason JW (2023)	37919549	245925	10356	Bivalent ligand 497	CIP-22|Bivalent_ligand_497	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111973	6046	DADB-17J1.3	BRD2	D6S113E|FSH|FSRG1|NAT|RING3|RNF3	9606	Homo sapiens	target	Standardized BVL Name: CIP-22 (VHL:MZ1---BRD2:BB2-109)	-
33084	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32145645	246255	10378	Bivalent ligand 502	6c|Bivalent_ligand_502	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107070	598	RP5-857M17.3	BCL2L1	BCL-XL/S|BCL2L|BCLX|BCLXL|BCLXS|Bcl-X|PPP1R52|bcl-xL|bcl-xS	9606	Homo sapiens	target	Standardized BVL Name: 6c (VHL:VHL ligand ---BCL-XL:ABT-263)	-
33086	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation 	recruited e3 ligase	Zhang X (2020)	32171162	246256	10352	Bivalent ligand 503	14o|Bivalent_ligand_503	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: 14o (VHL:VHL ligand --- EGFRL858R/T790M:XTF-262)	-
33108	108020	1654	-	DDX3X	CAP-Rf|DBX|DDX14|DDX3|HLP2	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Ciccosanti F (2021)	33781803	238050	9985	RK-33	3,7-Bis(4-methoxybenzyl)-3,7-dihydro-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one|2H-Diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one, 3,7-dihydro-3,7-bis[(4-methoxyphenyl)methyl]-	-	CHEMSPIDER	26383637	C23H20N6O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: DD3X3 inhibitor	COUMZXFUZDBRCZ-UHFFFAOYSA-N
33109	107068	596	-	BCL2	Bcl-2|PPP1R50	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Patten JJ (2022)	35992305	239003	9955	obatoclax	2-{(2Z)-2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl}-1H-indole|2-{(2Z)-2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-3-methoxy-2H-pyrrol-5-yl}-1H-indole|1H-Indole, 2-[(2Z)-2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-|Obatoclax|QN4128B52A	-	CHEMSPIDER	21430401	C20H19N3O	small molecule	-	803712-67-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: BCL2 inhibitor; Prevented ]80% SARS-CoV-2 infection in primary intestinal epithelial cell cultures.	RFTSSZJZXOSICM-GRSHGNNSSA-N
33147	117618	26227	RP4-683H9.1	PHGDH	3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2023)	36644320	239397	9954	NCT-503	1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-|N-(4,6-Dimethyl-2-pyridinyl)-4-[4-(trifluoromethyl)benzyl]-1-piperazinecarbothioamide|NCT-503|N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide	-	CHEMSPIDER	57621588	C20H23F3N4S	small molecule	-	1916571-90-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: PHGDH inhibitor; viral inhibition mechanism undetermined; Delta and Omicron variant tested	PJNSZIQUFLWRLH-UHFFFAOYSA-N
33148	109346	3099	-	HK2	HKII|HXK2	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2020)	32408336	223364	9980	2-Deoxy-D-glucose	2-Deoxy-D-glucose|2-DG|2-deoxyglucose|2-Deoxy-D-arabino-hexopyranose|D-arabino-Hexopyranose, 2-deoxy-|D-arabino-2-Desoxyhexose|(4R,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol|2-deoxy-D-glucopyranose	-	CHEMSPIDER	388402	C6H12O5	small molecule	-	154-17-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: HK2 inhibitor; viral inhibition mechanism undetermined	PMMURAAUARKVCB-CERMHHMHSA-N
33161	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Raymonda MH (2022)	34871905	239614	2916	Doramapimod	DSSTOX_RID_83151|KINOME_2137|CCG-264915|1-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|ZINC24044436|DORAMAPIMOD1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|NSC785337|AKOS005256489|S1574|ALBB-035131|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|MLS006010153|NCGC00241104-07|BIRB 0796|NSC-785337|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|1-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-3-(4-(2-(MORPHOLIN-4-YL)ETHOXY)NAPHTHALEN-1-YL)UREA|1-(3-(TERT-BUTYL)-1-(P-TOLYL)-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA.|CS-0219|BIRB796|1-(3-TERT-BUTYL-1-P-TOLYL-1H-PYRAZOL-5-YL)-3-(4-(2-MORPHOLINOETHOXY)NAPHTHALEN-1-YL)UREA|BIRB 796BS|MFCD09752957|BIRB 796 (DORAMAPIMOD)|UNII-HO1A8B3YVV|SR-00000002531|Q-101419|B96|EX-A4530|DB03044|D03736|TOX21_113386_1|AS-19375|BIRB 796 BS|SW219700-1|1-[5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-PYRAZOLYL]-3-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|285983-48-4|UREA, N-(3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL)-N'-(4-(2-(4-MORPHOLINYL)ETHOXY)-1-NAPHTHALENYL)-|UREA, N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-|BIRB-796 BS|DORAMAPIMOD (BIRB-796)|BIRB-796, 3|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA|1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3(4-(2-MORPHOLIN-4-YL-ETHOXY)NAPHTHALEN-1-YL)UREA|BIRB-796|FT-0667779|DSSTOX_GSID_48957|NCGC00241104-01|BIRB 796|BCPP000333|DORAMAPIMOD|BCP01896|1-[5-TERT-BUTYL-2-(P-TOLYL)PYRAZOL-3-YL]-3-[4-(2-MORPHOLINOETHOXY)-1-NAPHTHYL]UREA|CID_156422|BRD-K74065929-001-01-5|N-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA|TOX21_113386|GTPL5668|SMR004458704|1KV2|P38 MAP KINASE INHIBITOR X, BIRB 796 - CAS 285983-48-4|1-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-3-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|N-[3-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]- N'-[4-[2-(4-MORPHOLINYL)ETHOXY]-1-NAPHTHALENYL]-UREA|NCGC00241104-02|DSSTOX_CID_28883|DORAMAPIMOD [INN]|BIRB 796,DORAMAPIMOD|DORAMAPIMOD [USAN]|HMS3295M15|DORAMAPIMOD (USAN/INN)|CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=C(OCCN2CCOCC2)C=C1)C(C)(C)C|DTXSID2048957|DIARYL UREA COMPOUND 10|HMS3747G11|HO1A8B3YVV|DORAMAPIMOD (BIRB 796)|SR-00000002531-1|DORAMAPIMOD [WHO-DD]|BCP9000416|US8933228, BIRB 796|HY-10320|BIBR-796|AC-24379|HMS3655C07|DORAMAPIMOD [USAN:INN]|A819503|SB16634|Q27077098|BIRB-0796|3-[2-(4-METHYLPHENYL)-5-TERT-BUTYL-PYRAZOL-3-YL]-1-[4-(2-MORPHOLIN-4-YLETHOXY)NAPHTHALEN-1-YL]UREA|3-[3-TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-1-{4-[2-(MORPHOLIN-4-YL)ETHOXY]NAPHTHALEN-1-YL}UREA	-	DRUGBANK	DB03044	C31H37N5O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: p38 MAPK inhibitor; viral inhibition mechanism undetermined	MVCOAUNKQVWQHZ-UHFFFAOYSA-N
33172	108123	1786	-	DNMT1	ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Zhang Y (2022)	34672954	237984	918	Azacitidine	Azacitidine|Azacitidina|4-Amino-1-beta-D-ribofuranosyl-S-triazin-2(1H)-one|Azacitidinum|5 AZC|Azacytidine|5-Azacytidine	azacitidine|vidaza	DRUGBANK	DB00928	C8H12N4O5	small molecule	L01BC07	320-67-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: DNMT1 inhibitor; Viral inhibition in anti- SARS-CoV-2 infection assays in Vero E6 cells.	NMUSYJAQQFHJEW-KVTDHHQDSA-N
33188	107027	545	-	ATR	FCTCS|FRP1|MEC1|SCKL|SCKL1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10213	berzosertib	VE-822|UNII:L423PRV3V3|VX-970|Berzosertib|L423PRV3V3|5-[4-(Isopropylsulfonyl)phenyl]-3-(3-{4-[(methylamino)methyl]phenyl}-1,2-oxazol-5-yl)-2-pyrazinamine|2-Pyrazinamine, 3-[3-[4-[(methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-	-	CHEMSPIDER	30773968	C24H25N5O3S	small molecule	-	1232416-25-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: ATR inhibitor (PMID: 31018854); viral inhibition mechanism undetermined	JZCWLJDSIRUGIN-UHFFFAOYSA-N
33197	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10202	Torin 2	Torin 2|9-(6-AMINOPYRIDIN-3-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H,2H-BENZO[H]1,6-NAPHTHYRIDIN-2-ONE|Benzo[h][1,6]naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-|9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one	-	CHEMSPIDER	26232176	C24H15F3N4O	small molecule	-	1223001-51-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor (PMID: 26239364); viral inhibition mechanism undetermined	GUXXEUUYCAYESJ-UHFFFAOYSA-N
33198	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10207	vistusertib	AZD-2014|AZD 2014|vistusertib	-	CHEMSPIDER	28294977	C25H30N6O3	small molecule	-	1009298-59-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor (PMID: 27031247); viral inhibition mechanism undetermined	JUSFANSTBFGBAF-IRXDYDNUSA-N
33199	108757	2475	-	MTOR	FRAP|FRAP1|FRAP2|RAFT1|RAPT1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10258	dactolisib	BEZ-235|2-Methyl-2-{4-[3-methyl-2-oxo-8-(3-quinolinyl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile|Benzeneacetonitrile, 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alpha-dimethyl-|NVP-BEZ 235|NVP-BEZ235|BEZ 235|NVP-BEZ235-NX|BEZ235|Dactolisib|NVPBEZ235|NVP BEZ235	-	CHEMSPIDER	10151099	C30H23N5O	small molecule	-	915019-65-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: mTOR inhibitor; viral inhibition mechanism undetermined	JOGKUKXHTYWRGZ-UHFFFAOYSA-N
33281	110465	4322	-	MMP13	CLG3|MANDP1|MMP-13	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Yamamoto M (2021)	888800000485	232833	7270	CTS-1027	4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL]-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE|193022-04-7|RS-130830|Ro-1130830	-	DRUGBANK	DB08490	C19H20ClNO6S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:MMP13 inhibitor; exact viral inhibition mechanism undetermined but authors show disruption of the metalloproteinase pathway is involved	ROSNVSQTEGHUKU-UHFFFAOYSA-N
33284	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Yang X (2022)	35723434	232852	10245	SGC-CK2-1	Propanamide, N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]-|N-(5-{[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino}-2-methylphenyl)propanamide	-	CHEMSPIDER	98644473	C20H21N7O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:CSNK2A inhibitor; exact viral inhibition mechanism undetermined	YKDZIFFKQUNVHH-UHFFFAOYSA-N
33305	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor/sars-cov-2 activator	target	Chen IP (2022)	35839775	232204	10195	dBET6	-	-	CHEMSPIDER	71046111	C42H45ClN8O7S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:BRD4 inhibitor; BRD3 inhibition results in enhanced viral replication in cultured cells and in mice	JGQPZPLJOBHHBK-UFXYQILXSA-N
33307	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor/sars-cov-2 activator	target	Chen IP (2022)	35839775	232204	10243	JQ1	JQ1|(6s)-6-(2-Tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepin-10-ium|(+)-JQ1|(S)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate|6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6S)-|JQ-1|2-Methyl-2-propanyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate|MFCD22683748|1MRH0IMX0W|JQ 1(+)	-	CHEMSPIDER	26323622	C23H25ClN4O2S	small molecule	-	1268524-70-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:BRD4 inhibitor; BRD3 inhibition results in enhanced viral replication in cultured cells and in mice	DNVXATUJJDPFDM-KRWDZBQOSA-N
33360	112550	6667	-	SP1	-	9606	Homo sapiens	sars-cov-2 inhibitor	target	Han H (2024)	38375778	241442	5643	Plicamycin	Mithramycine|Mithracin|Mithramycinum|Plicamycine|Plicamycin|Plicamycinum|Mithramycin|Aureolic acid	-	DRUGBANK	DB06810	C52H76O24	small molecule	L01DC02	18378-89-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: SP1 inhibitor, mechanism undetermined; antiviral activity in cells and hamsters	CFCUWKMKBJTWLW-BKHRDMLASA-N
33361	113348	7514	-	XPO1	CRM1|emb|exp1	9606	Homo sapiens	sars-cov-2 activator	target	Rahman MM (2023)	888800000921	241443	10263	Selinexor	2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-|(2Z)-3-{3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-N'-(2-pyrazinyl)acrylohydrazide|selinexor	-	CHEMSPIDER	32701989	C17H11F6N7O	small molecule	-	1393477-72-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: XPO1 inhibitor, mechanism undetermined; enhances SARS-CoV-2 infection and replication	DEVSOMFAQLZNKR-RJRFIUFISA-N
33362	107777	1387	-	CREBBP	CBP|KAT3A|RSTS	9606	Homo sapiens	sars-cov-2 inhibitor	target	Kelch MA (2023)	37342561	241452	10275	PRI-724	PRI-724|N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide|2H-Pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide, hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-	-	CHEMSPIDER	19546236	C33H32N4O4	small molecule	-	847591-62-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: CBP-CTNNB1 interaction inhibitor; CBP interactor; antiviral activity against SARS-CoV-2 Wuhan-Hu-1, Zeta, Epsilon, Kappa, Alpha, Beta, Delta, and Omicron variants, SARS-CoV and MERS	HQWTUOLCGKIECB-UHFFFAOYSA-N
33417	111317	5300	-	PIN1	DOD|UBL5	9606	Homo sapiens	sars-cov-2 inhibitor	target	Aviner R (2023)	888800000985	244285	10191	Juglone	Juglone|Regianin|Nucin|5-Hydroxy-1,4-naphthoquinone|5-HNQ|5-Hydroxy-1,4-naphthalenedione|5-hydroxynaphthalene-1,4-dione|1,4-Naphthalenedione, 5-hydroxy-|5-Hydroxy-1,4-naphthochinone|1909764|5-hydroxy-1,4-dihydronaphthalene-1,4-dione	-	CHEMSPIDER	3674	C10H6O3	small molecule	-	481-13-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human PIN1 inhibitor; antiviral activity against SARS-CoV-2 in Vero E6 cells	KQPYUDDGWXQXHS-UHFFFAOYSA-N
33426	106710	207	-	AKT1	AKT|CWS6|PKB|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Liu Q (2022)	35858407	244644	10172	GSK-690693	GSK-690693|4-{2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methyl-3-butyn-2-ol|3-Butyn-2-ol, 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-|MFCD14105605|4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol	-	CHEMSPIDER	20557532	C21H27N7O3	small molecule	-	937174-76-0	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: AKT inhibitor; SIRT5 activator; antiviral activity against SARS-CoV-2 in Caco-2 cells	KGPGFQWBCSZGEL-ZDUSSCGKSA-N
33449	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10330	4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole	SW218141-2|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE;SB-203580|SR-01000597367|J-008891|HMS3267B07|BCP01763|CDMGBJANTYXAIV-UHFFFAOYSA-N|RWJ-64809|US9187470, 104 (SB203580)|4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-5-(4-PYRIDYL)-1H-IMIDAZOLE|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]- & Z-100|4-[5-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-3H-IMIDAZOL-4-YL]PYRIDINE|OU13V1EYWQ|SB 203580|AKOS015994568|HMS1792H05|AM81234|4-{4-(4-FLUOROPHENYL)-2-[4-(METHANESULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|PB-203580|UNII-OU13V1EYWQ|HMS3403H05|RAC-4-(5-(4-FLUOROPHENYL)-2-(4-((R)- METHANESULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|NCGC00025035-04|PB203580|HMS3676M17|CCG-206878|BIO1_000745|4-{4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL}PYRIDINE|HB1302|NCGC00025035-05|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE|S1076|F0864|HMS3244I16|BIO1_000256|NCGC00025035-02|A15256|NCGC00025035-01|J-513573|RWJ 64809|K00038|PYRIDINE, 4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)-|ES-0013|NSC-755772|PYRIDINE, 4-[4-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-5-YL]-|TOCRIS-1402|4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)PYRIDINE|4-[4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|PYRIDINE, 4-(5-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-4-YL)-|SB203580|4-[4-(4-FLUOROPHENYL)-2-(4-METHANESULFINYLPHENYL)-1H-IMIDAZOL-5-YL]PYRIDINE|BIRB-203580|4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE|HMS3295M11|NSC755772|BRD-A37704979-003-01-2|SB 203580, SOLID, >=98% (HPLC)|SB 203580 & Z-100|SR-01000597367-1|CBIOL_001970|ADEZMAPIMOD|NCGC00381704-12|PYRIDINE, 4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFINYL)PHENYL]-1H-IMIDAZOL-YL]-|KINOME_2521|4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE|ADEZMAPIMOD [INN]|SMR004701767|1PME|TOCRIS-1202|SB16633|MLS006010840|HMS3244I15|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)-PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|AC-32046|BIO1_001234|4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)1H-IMIDAZOLE|EX-A134|GTPL5269|NCGC00025035-03|SB-203580|DTXSID2040577|CS-0140|152121-47-6|PB 203580|FT-0674525|BIRB203580|4-(4-(4-FLUOROPHENYL)-2-(4-(METHYLSULFINYL)PHENYL)-1H-IMIDAZOL-5-YL)PYRIDINE|HMS3412M17|CID_176155|F17411|HMS3654M15|SB 203580 - CAS 152121-47-6|SB203580,RWJ 64809,PB 203580|BRD-A37704979-001-02-4|Q7389023|C21H16FN3OS|BCPP000074|RWJ64809|HMS3244J15|MFCD00922198|HMS1990H05|HY-10256|AKOS005145971|HMS3229O04|BSPBIO_001104	-	PUBCHEM	176155	C21H16FN3OS	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human p38 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	CDMGBJANTYXAIV-UHFFFAOYSA-N
33450	107841	1457	-	CSNK2A1	CK2A1|CKII|CSNK2A3	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10331	Silmitasertib	GTPL8126|J-516169|EX-8673|HMS3244N13|NSC-761193|AS-16253|EN300-6482034|5-[(3-CHLOROPHENYL)AMINO]PYRIDO[4,3-C]QUINOLINE-8-CARBOXYLIC ACID|SB17201|Q27076934|5-((3-CHLOROPHENYL)AMINO)BENZO-[C][2,6]NAPHTHYRIDINE-8-CARBOXYLIC ACID|CX-4945|HMS3746E13|CX-4945 (SILMITASERTIB)|CCG-264955|BCP02399|HMS3244M14|SILMITASERTIB [INN]|HMS3244M13|1009820-21-6|CX-4945,CAS:1009820-21-6|5-(3-CHLOROPHENYLAMINO)BENZO(C)(2,6)NAPHTHYRIDINE-8-CARBOXYLIC ACID|5-((3-CHLOROPHENYL)AMINO)-BENZO(C)-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID|C19H12CLN3O2|5-[(3-CHLOROPHENYL)AMINO]-BENZO[C]-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID|CX-4945 FREE ACID|5-[(3-CHLOROPHENYL)AMINO]BENZO[C]-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID|DB15408|SILMITASERTIBUM|5-[(3-CHLOROPHENYL)AMINO]BENZO[C][2,6]NAPHTHYRIDINE-8-CARBOXYLIC ACID|5-((3-CHLOROPHENYL)AMINO)BENZO[C][2,6]NAPHTHYRIDINE-8-CARBOXYLIC ACID|FT-0723994|5-[(3-CHLOROPHENYL)AMINO]BENZO[C]2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID|CS-0563|NCGC00263192-02|NCGC00263192-09|AC-28426|W-204393|HY-50855|SILMITASERTIB|J-000296|5-((3-CHLOROPHENYL)AMINO)BENZO(C)(2,6)NAPHTHYRIDINE-8-CARBOXYLIC ACID|BCP9000560|SILMITASERTIB; CX 4945|NSC-800885|CX-4945 (SILMITASERIB)|A25034|MFCD13184796|CX 4945 (SILMITASERTIB)|BENZO(C)-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID, 5-((3-CHLOROPHENYL)AMINO)-|SY069677|DTXCID9066093|AKOS005266722|CX4945 (SILMITASERTIB)|C6RWP0N0L2|SW218157-2|SILMITASERTIB (CX-4945)|HMS3655F16|BENZO[C]-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID, 5-[(3-CHLOROPHENYL)AMINO]-|EX-A070|S2248|5-(3-CHLOROANILINO)BENZO[C][2,6]NAPHTHYRIDINE-8-CARBOXYLIC ACID|CX4945|CX 4945|UNII-C6RWP0N0L2|DTXSID40143602|SILMITASERTIB [WHO-DD]|5-(3-CHLOROPHENYLAMINO)BENZO[C][2,6]NAPHTHYRIDINE-8-CARBOXYLIC ACID|NSC761193|3NG|NSC800885|NCGC00263192-01	-	PUBCHEM	24748573	C19H12ClN3O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human CSNK2A1 and CSNK2A2 inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	MUOKSQABCJCOPU-UHFFFAOYSA-N
33452	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10332	Gilteritinib	6-ETHYL-3-(3-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)ANILINO)-5-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)PYRAZINE-2-CARBOXAMIDE|MFCD28144685|NSC-787854|AKOS030234455|2-PYRAZINECARBOXAMIDE, 6-ETHYL-3-((3-METHOXY-4-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PHENYL)AMINO)-5-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)-|NSC787854|6-ETHYL-3-((3-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)PHENYL)AMINO)-5-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)PYRAZINE-2-CARBOXAMIDE|EX-A2775|GILTERITINIB HCL|CS-3885|GILTERITINIB [USAN]|2-PYRAZINECARBOXAMIDE, 6-ETHYL-3-[[3-METHOXY-4-[4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL]PHENYL]AMINO]-5-[(TETRAHYDRO-2H-PYRAN-4-YL)AMINO]-|6-ETHYL-3-{3-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]ANILINO}-5-[(OXAN-4-YL)AMINO]PYRAZINE-2-CARBOXAMIDE|DB12141|US8969336, 577|GILTERITINIB (ASP-2215)|GILTERITINIB [WHO-DD]|6-ETHYL-3-((3-METHOXY-4-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PHENYL)AMINO)-5-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)-2-PYRAZINECARBOXAMIDE|GILTERITINIB (USAN/INN)|DTXSID701027949|66D92MGC8M|GILTERITINIB [USAN:INN]|ASP-2215|NSC-788454|C6F|NCGC00481652-02|L01XE54|D10709|NSC800106|6-ETHYL-3-({3-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]PHENYL}AMINO)-5-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)PYRAZINE-2-CARBOXAMIDE|GTPL8708|CCG-270016|AS-35199|NSC788454|1254053-43-4|A901674|Q27077802|XOSPATA|ASP2215|GILTERITINIBUM|6-ETHYL-3-((3-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)PHENYL)-AMINO)-5-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)PYRAZINE-2-CARBOXAMIDE|GILTERITINIB (ASP2215)|GILTERITINIB(ASP2215)|NSC-800106|GILTERITINIB [INN]|6-ETHYL-3-{3-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]ANILINO}-5-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)PYRAZINE-2-CARBOXAMIDE|BCP28756|UNII-66D92MGC8M|NCGC00481652-01|AC-29030|SB16988|NSC-787846|SY099594|NSC787846|HY-12432|US8969336, 547|6-ETHYL-3-(3-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)ANILINO)-5-((OXAN-4-YL)AMINO)PYRAZINE-2-CARBOXAMIDE|BG166434|ASP 2215|6-ETHYL-3-[[3-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]PHENYL]AMINO]-5-(OXAN-4-YLAMINO)PYRAZINE-2-CARBOXAMIDE|S7754|GILTERITINIB [MI]|6-ETHYL-3-[[3-METHOXY-4-[4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDYL]PHENYL]AMINO]-5-[(TETRAHYDROPYRAN-4-YL)AMINO]PYRAZINE-2-CARBOXAMIDE|GILTERITINIB|6-ETHYL-3-[3-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]ANILINO]-5-(OXAN-4-YLAMINO)PYRAZINE-2-CARBOXAMIDE	-	PUBCHEM	49803313	C29H44N8O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human AXL inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	GYQYAJJFPNQOOW-UHFFFAOYSA-N
33454	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10333	Ralimetinib	5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL)-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO(4,5-B)PYRIDIN-2-YLAMINE|UNII-73I34XW4HD|SB16635|NCGC00346537-01|XPPBBJCBDOEXDN-UHFFFAOYSA-N|NSC-766820|LSN-2322600 FREE BASE|BCPP000180|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|RALIMETINIB [USAN]|Q27088512|862505-00-8|RALIMETINIB [INN]|LY 2228820|RALIMETINIB [USAN:INN]|LY2228820 FREE BASE|5-(2-(TERT-BUTYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|862505-00-8 (FREE BASE)|RALIMETINIB [WHO-DD]|NCGC00346537-05|LY22288220|DB11787|AKOS027282678|HMS3674E21|3H-IMIDAZO(4,5-B)PYRIDIN-2-AMINE, 5-(2-(1,1-DIMETHYLETHYL)-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-(2,2-DIMETHYLPROPYL)-|GTPL7959|3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,5-[2-(1,1-DIMETHYLETHYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)-|CS-0008496|D10658|RALIMETINIB (USAN/INN)|(5P)-5-[2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-3-(2,2-DIMETHYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|5-(2-TERT-BUTYL-4-(4-FLUOROPHENYL)-1H-IMIDAZOL-5-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|DTXSID00235456|HY-13241A|BCP02033|LY-2228820|73I34XW4HD|RALIMETINIB ( LY2228820)|NSC766820|NCGC00346537-03|E98891|RALIMETINIB|YXT|5-(2-(TERT-BUTYL)-5-(4-FLUOROPHENYL)-1H-IMIDAZOL-4-YL)-3-NEOPENTYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE|LSN2322600 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUORO-PHENYL)-1H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYL-PROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-YLAMINE|LY-2228820 FREE BASE|5-[2-TERT-BUTYL-5-(4-FLUOROPHENYL)-3H-IMIDAZOL-4-YL]-3-(2,2-DIMETHYLPROPYL)IMIDAZO[5,4-B]PYRIDIN-2-AMINE|NSC785335|NSC-785335|BCP9000871|FT-0727743	-	PUBCHEM	11539025	C24H29FN6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK11/MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in Vero-E6 cells	XPPBBJCBDOEXDN-UHFFFAOYSA-N
33456	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10335	p38alpha Inhibitor 1	5-(2,4-DIFLUOROPHENOXY)-N-(2-(DIMETHYLAMINO)ETHYL)-1-ISOBUTYL-1H-INDAZOLE-6-CARBOXAMIDE|ARRY-797|1034189-82-6|CS-0085271|P38?? INHIBITOR 1|EX-A3148|ARRY-371797|ARRY371797|1036404-17-7|COMPOUND 7 [PMID: 19950901]|ARRY797|P38A INHIBITOR 1|P38 ALPHA INHIBITOR 1|P38-ALPHA- INHIBITOR 1|-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|P38ALPHA INHIBITOR 1|HY-114423|AKOS040733949|ARRY-797; ARRY-371797|P38|A INHIBITOR 1|MS-27245|5-(2,4-DIFLUOROPHENOXY)-N-[2-(DIMETHYLAMINO)ETHYL]-1-(2-METHYLPROPYL)INDAZOLE-6-CARBOXAMIDE|GTPL11095	-	PUBCHEM	46883775	C22H26F2N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human MAPK14 inhibitor;  antiviral activity against SARS-CoV-2 in ACE2-A549 cells	IFGWYHGYNVGVRB-UHFFFAOYSA-N
33457	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10176	dinaciclib	Dinaciclib|SCH 727965|SCH727965|2-[(2S)-1-(3-Ethyl-7-{[(1-oxido-3-pyridinyl)methyl]amino}pyrazolo[1,5-a]pyrimidin-5-yl)-2-piperidinyl]ethanol|4V8ECV0NBQ|2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-	-	CHEMSPIDER	25027387	C21H28N6O2	small molecule	-	779353-01-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human CDK2/5/9 inhibitor;  antiviral activity against SARS-CoV-2 in VERO-E6 and ACE2-A549 cells	PIMQWRZWLQKKBJ-SFHVURJKSA-N
33464	113348	7514	-	XPO1	CRM1|emb|exp1	9606	Homo sapiens	inhibitor/sars-cov-2 activator	target	Rahman MM (2023)	888800000921	241443	10337	Selinexor	MFCD27987944|SELINEXOR [USAN]|SELINEXOR [MI]|D11222|KPT-330|1393477-72-9|A857179|N-HYDROXY-N'-(2-PHENYLETHYL)ISOPHTHALAMIDE|SELINEXOR [INN]|J-690156|SELINEXOR FREE BASE|(2Z)-3-{3-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOL-1-YL}-N'-(PYRAZIN-2-YL)PROP-2-ENEHYDRAZIDE|SELINEXORUM|CRM1 NUCLEAR EXPORT INHIBITOR KPT-330|COMPOUND 70 (WO2013019561A1)|L01XX66|GTPL10036|EX-A870|NCGC00386310-01|(Z)-3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-N'-(PYRAZIN-2-YL)ACRYLOHYDRAZIDE|SELINEXOR [WHO-DD]|2-PROPENOIC ACID, 3-[3-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOL-1-YL]-, 2-(2-PYRAZINYL)HYDRAZIDE, (2Z)-|CCG-269161|XPOVIO|NSC-780203|(Z)-3-[3-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOL-1-YL]-N'-PYRAZIN-2-YLPROP-2-ENEHYDRAZIDE|NCGC00386310-03|COMPOUND 70 [WO2013019561A1]|31TZ62FO8F|NSC780203|NSC-781780|SELINEXOR [USAN:INN]|SELINEXOR;(Z)-3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-N'-(PYRAZIN-2-YL)ACRYLOHYDRAZIDE|KPT330;SELINEXOR|SELINEXOR (USAN/INN)|1621865-82-4|KPT-330(SELINEXOR)|HY-17536|SELECTIVE INHIBITOR OF NUCLEAR EXPORT KPT-330|AC-33645|XPOVIO (TN)|ATG-010|SELINEXOR (KPT-330)|DTXSID801026013|EN300-7360494|S7252|Q27256082|DB11942|UNII-31TZ62FO8F|KPT330|KPT 330|SINE KPT-330|2-PROPENOIC ACID, 3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-, 2-(2-PYRAZINYL)HYDRAZIDE, (2Z)-|SELINEXOR [ORANGE BOOK]|NSC781780|NEXPOVIO|AKOS027325566|(2Z)-2-(2-PYRAZINYL)HYDRAZIDE-3-[3-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-1H-1,2,4-TRIAZOL-1-YL]-2-PROPENOIC ACID|SELINEXOR|SW219336-1|BS-15022	-	PUBCHEM	71481097	C17H11F6N7O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human XPO1 inhibitor;  the authors show that Selinexor treatment unexpectedly enhances the in vitro replication of coronaviruses, including SARS-CoV-2 A549ACE2 cells	DEVSOMFAQLZNKR-RJRFIUFISA-N
33465	107880	1499	OK/SW-cl.35	CTNNB1	CTNNB|MRD19|armadillo	9606	Homo sapiens	sars-cov-2 inhibitor	target	Kelch MA (2023)	37342561	241452	10338	Foscenvivint	2H-PYRAZINO(2,1-C)(1,2,4)TRIAZINE-1(6H)-CARBOXAMIDE, HEXAHYDRO-2,9-DIMETHYL-4,7-DIOXO-N-(PHENYLMETHYL)-6-((4-(PHOSPHONOOXY)PHENYL)METHYL)-8-(8-QUINOLINYLMETHYL)-, (6S,9S,9AS)-|4-(((6S,9S,9AS)-1-(BENZYLCARBAMOYL)-2,9-DIMETHYL-4,7- DIOXO-8-((QUINOLIN-8-YL)METHYL)OCTAHYDRO-2HPYRAZINO(2,1-C)(1,2,4)TRIAZIN-6-YL)METHYL)PHENYL DIHYDROGEN PHOSPHATE|1198780-38-9|43Y934BBZ6|UNII-43Y934BBZ6|PRI724|(S,S)-ICG-001|1422253-38-0 (PRI-724)|HY-112045|FOSCENVIVINT|EX-A3641|[4-[[(6S,9S,9AS)-1-(BENZYLCARBAMOYL)-2,9-DIMETHYL-4,7-DIOXO-8-(QUINOLIN-8-YLMETHYL)-3,6,9,9A-TETRAHYDROPYRAZINO[2,1-C][1,2,4]TRIAZIN-6-YL]METHYL]PHENYL] DIHYDROGEN PHOSPHATE|DB15034|1422253-38-0|4-(((6S,9S,9AS)-1-(BENZYLCARBAMOYL)-2,9-DIMETHYL-4,7-DIOXO-8-(QUINOLIN-8-YLMETHYL)OCTAHYDRO-2H-PYRAZINO[2,1-C][1,2,4]TRIAZIN-6-YL)METHYL)PHENYL DIHYDROGEN PHOSPHATE|AC-31548||A-CATENIN/CBP-IN-1|4-(((6S,9S,9AS)-1-(BENZYLCARBAMOYL)-2,9-DIMETHYL-4,7-DIOXO-8-(QUINOLIN-8-YLMETHYL)OCTAHYDRO-1H-PYRAZINO[2,1-C][1,2,4]TRIAZIN-6-YL)METHYL)PHENYL DIHYDROGEN PHOSPHATE|PRI-724|FOSCENVIVINT [INN]|CS-0042484|(6S,9S,9AS)-HEXAHYDRO-2,9-DIMETHYL-4,7-DIOXO-N-(PHENYLMETHYL)-6-[[4-(PHOSPHONOOXY)PHENYL]METHYL]-8-(8-QUINOLINYLMETHYL)-2H-PYRAZINO[2,1-C][1,2,4]TRIAZINE-1(6H)-CARBOXAMIDE	-	PUBCHEM	71509318	C33H35N6O7P	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: small-molecule inhibitor of the Beta-catenin/CBP interaction; shows anti-viral acitivity against multiple coronaviruses including SARS-CoV-2 variants (Ancestral variants: B (FFM5), B.1 (FFM7, D614G); variants of interest (VOI): P.2 (Zeta), B.1.429 (Epsilon), B.1.617.1 (Kappa); deescalated variants of concern (VOC): B.1.1.7 (Alpha), B.1.351 (Beta), B.1.617.2 (Delta); VOC: B.1.1.529 BA.1, BA.2, and BA.5 (Omicron), SARS-CoV-1, and Influenza A virus in A549-AT cells	VHOZWHQPEJGPCC-AZXNYEMZSA-N
33496	110852	4780	-	NFE2L2	NRF2	9606	Homo sapiens	degradation	target	Ji J (2023)	36892138	247218	10736	Bivalent ligand 506	ARE-PROTAC C2|bivalent_ligand_506	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ARE-PROTAC C2 (CRBN:lenalidomide --- NFE2L2:5-TGAG/CNNNGC-3)	-
33497	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Rosenberg SC (2023)	36773603	247269	10737	Bivalent ligand 507	GNE-579|bivalent_ligand_507	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110852	4780	-	NFE2L2	NRF2	9606	Homo sapiens	target	Standardized BVL Name: GNE-579 (VHL:VH032 --- EGFRExon19/L858R:Compound A)	-
33499	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hung CL (2023)	36893587	247251	10738	Bivalent ligand 508	ITRI-90|bivalent_ligand_508	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ITRI-90 (VHL:VHL HCl salt --- AR/AR-V(LBD):AZD3514 )	-
33501	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hung CL (2023)	36893587	247251	10739	Bivalent ligand 509	ITRI-125|bivalent_ligand_509	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: ITRI-125 (VHL:VHL HCl salt --- AR/AR-V(LBD):AZD3514 )	-
33505	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Lee GT (2021)	33277442	229865	10741	Bivalent ligand 511	MTX-23|bivalent_ligand_511	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: MTX-23 (VHL:CRL2VHL compound --- AR/AR-V7:AR DBD binding molecule)	-
33510	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Xie H (2023)	36749666	248602	10743	Bivalent ligand 513	Degrader 13|bivalent_ligand_513	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Degrader 13 (CRBN: 1,2,3-trisubstituted PDHU --- BRD4:JQ1)	-
33539	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10751	Bivalent ligand 522	PROTAC-1|bivalent_ligand_522	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-1 (VHL:VH032 --- BRAF:S5)	-
33541	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10752	Bivalent ligand 523	PROTAC-2|bivalent_ligand_523	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-2 (VHL:VH032 --- BRAF:S5)	-
33543	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10753	Bivalent ligand 524	PROTAC-3|bivalent_ligand_524	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-3 (VHL:VH032 --- BRAF:S5)	-
33545	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10751	Bivalent ligand 522	PROTAC-1|bivalent_ligand_522	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-1 (VHL:VH032 --- KDR:S5)	-
33547	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	37030566	250553	10752	Bivalent ligand 523	PROTAC-2|bivalent_ligand_523	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109992	3791	-	KDR	CD309|FLK1|VEGFR|VEGFR2	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-2 (VHL:VH032 --- KDR:S5)	-
33551	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bouguenina H (2023)	37418539	256614	8493	Bivalent ligand 112	VZ185|Bivalent_ligand_112	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122430	65980	UNQ3040/PRO9856	BRD9	LAVS3040|PRO9856	9606	Homo sapiens	target	Standardized BVL Name: VZ185 (VHL:VHL4 --- BRD9: BRDL1)	-
33560	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Bai L (2017)	28209615	256615	10755	Bivalent ligand 526	BETd-246|bivalent_ligand_526	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BETd-246 (CRBN:thalidomide --- BRD4:BETi-211)	-
33563	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Song H (2024)	38194774	256616	10757	Bivalent ligand 528	18a|bivalent_ligand_528	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: 18a (BIRC2:bestatin --- GPX4:RSL3)	-
33566	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu J (2023)	37289649	256617	10758	Bivalent ligand 529	BD-7148|bivalent_ligand_529	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BD-7148 (CRBN:pomalidomide --- BRD4:QCA276)	-
33568	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu J (2023)	37289649	256617	10759	Bivalent ligand 530	BD-9136|bivalent_ligand_530	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BD-9136 (CRBN:pomalidomide --- BRD4:QCA276)	-
33584	110172	3984	-	LIMK1	LIMK|LIMK-1	9606	Homo sapiens	degradation	target	Schroeder M (2024)	38177131	256619	10764	Bivalent ligand 535	DBt-10|bivalent_ligand_535	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DBt-10 (DCAF1: DCAF1 Binder 13 --- LIMK1:BTKi)	-
33586	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	De Dominici M (2020)	32040545	256620	10765	Bivalent ligand 536	YX-2-107|bivalent_ligand_536	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YX-2-107 (CRBN:thalidomide --- CDK6:palbociclib)	-
33588	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK6:palbociclib)	-
33590	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	De Dominici M (2020)	32040545	256620	10766	Bivalent ligand 537	YX-2-233|bivalent_ligand_537	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YX-2-233 (MDM2:RG7112 --- CDK4:palbociclib)	-
33593	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Winzker M (2020)	31829492	256621	10768	Bivalent ligand 539	PROTAC 5|bivalent_ligand_539	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111173	5147	-	PDE6D	JBTS22|PDED	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 5 (VHL:VHL ligand --- PDE6D:deltasonamide1)	-
33598	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK6:palbociclib)	-
33600	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10770	Bivalent ligand 541	pal-pom|bivalent_ligand_541	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pal-pom (CRBN:pomalidomide --- CDK4:palbociclib)	-
33602	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK6:ribociclib)	-
33604	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Zhao B (2019)	30758029	256623	10771	Bivalent ligand 542	rib-pom|bivalent_ligand_542	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: rib-pom (CRBN:pomalidomide --- CDK4:ribociclib)	-
33606	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ding M (2023)	36563515	256624	10772	Bivalent ligand 543	degrader 8b|bivalent_ligand_543	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: degrader 8b (CRBN:lenalidomide --- BRD4:JQ1)	-
33608	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Wang Y (2021)	33839580	254238	10773	Bivalent ligand 544	Compound 21a|bivalent_ligand_544	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 21a (CRBN:thalidomide --- PD-L1 :BMS-37 diaryl ether analogue)	-
33613	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Aublette MC (2022)	35231578	254243	10776	Bivalent ligand 547	MA055|bivalent_ligand_547	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: MA055 (VHL:VH032 --- Wee1:AZD1775)	-
33617	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37703322	254337	10779	Bivalent ligand 550	compound 3b|bivalent_ligand_550	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115760	10498	-	CARM1	PRMT4	9606	Homo sapiens	target	Standardized BVL Name: compound 3b (VHL:VHL-1 --- CARM1:TP-064)	-
33619	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie H (2023)	37703322	254337	10780	Bivalent ligand 551	compound 3e|bivalent_ligand_551	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115760	10498	-	CARM1	PRMT4	9606	Homo sapiens	target	Standardized BVL Name: compound 3e (VHL:VHL-1 --- CARM1:TP-064)	-
33622	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK4:palbociclib)	-
33624	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Verano AL (2022)	36007246	256625	10781	Bivalent ligand 552	ALV-07-082-03|bivalent_ligand_552	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ALV-07-082-03 (CRBN: DKY709 --- CDK6:palbociclib)	-
33629	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu X (2022)	36007011	256627	10783	Bivalent ligand 554	XL01126|bivalent_ligand_554	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	125700	120892	-	LRRK2	AURA17|DARDARIN|PARK8|RIPK7|ROCO2	9606	Homo sapiens	target	Standardized BVL Name: XL01126 (VHL:VH101 --- LRRK2:HG-10-102-01)	-
33632	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Qin Q (2022)	35978496	256628	10784	Bivalent ligand 555	PROTAC A13|bivalent_ligand_555	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC A13 (CRBN:pomalidomide --- PTK2:PF-562271 derivative 1)	-
33637	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bhumireddy A (2022)	34767914	254422	10787	Bivalent ligand 558	Compound 6|bivalent_ligand_558	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Compound 6 (VHL:VHL ligand Compound 11 --- AR-V7:VPC-14228)	-
33639	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Shibata N (2022)	35085722	254450	10788	Bivalent ligand 559	Compound 5a/SNIPER(TACC3)-11|bivalent_ligand_559	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	target	Standardized BVL Name: Compound 5a/SNIPER(TACC3)-11 (cIAP1:LCL161 derivative Compound 11 --- FGFR3-TACC3:KHS108)	-
33645	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Luo G (2021)	34094835	254500	10791	Bivalent ligand 562	21c|bivalent_ligand_562	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109399	3156	-	HMGCR	LDLCQ3	9606	Homo sapiens	target	Standardized BVL Name: 21c (VHL:VHL231 --- HMGCR:lactone opened lovastatin acid)	-
33647	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Luo G (2021)	34094835	254500	10792	Bivalent ligand 563	21b|bivalent_ligand_563	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109399	3156	-	HMGCR	LDLCQ3	9606	Homo sapiens	target	Standardized BVL Name: 21b (VHL:VHL231 --- HMGCR:lactone lovastatin acid)	-
33652	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2021)	34788776	254514	10794	Bivalent ligand 565	ha-PROTAC 13|bivalent_ligand_565	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 13 (CRBN:lenalidomide --- EGFRDel19:HALG-gefitinib 4-anilinoquinazoline core)	-
33654	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2021)	34788776	254514	10795	Bivalent ligand 566	PROTAC 11|bivalent_ligand_566	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 11 (CRBN:lenalidomide --- EGFRDel19:gefitinib 4-anilinoquinazoline core)	-
33659	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xu H (2021)	34124002	254519	10798	Bivalent ligand 569	Compound 3|bivalent_ligand_569	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113222	7376	-	NR1H2	LXR-b|LXRB|NER|NER-I|RIP15|UNR	9606	Homo sapiens	target	Standardized BVL Name: Compound 3 (VHL:VH032 --- LXRB:GW3965)	-
33671	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Miller DSJ (2022)	35814929	256633	10804	Bivalent ligand 575	CST905|bivalent_ligand_575	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107141	673	-	BRAF	B-RAF1|BRAF1|NS7|RAFB1	9606	Homo sapiens	target	Standardized BVL Name: CST905 (VHL:VH032 --- BRAF:PLX7683)	-
33673	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wu Y (2022)	35755293	256634	10805	Bivalent ligand 576	PROTAC A7|bivalent_ligand_576	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	target	Standardized BVL Name: PROTAC A7 (VHL:VHL-1 --- NAMPT:MS7)	-
33675	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Swartzel JC (2022)	35749470	256635	10806	Bivalent ligand 577	JCS-1|bivalent_ligand_577	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	118787	28960	HSPC015	DCPS	DCS1|HINT-5|HINT5|HSL1	9606	Homo sapiens	target	Standardized BVL Name: JCS-1 (VHL:VL285 --- DCPS:RG3039)	-
33677	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Sun Y (2022)	35717870	256636	10807	Bivalent ligand 578	SYL2158|bivalent_ligand_578	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120250	54904	DC28	WHSC1L1	NSD3|pp14328	9606	Homo sapiens	target	Standardized BVL Name: SYL2158 (VHL:VHL-1 --- NSD3:BI-9321)	-
33684	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Yang H (2019)	31769449	256639	10810	Bivalent ligand 581	NH2|bivalent_ligand_581	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NH2 (CRBN:pomalidomide --- HDAC6:Nexturastat A (Nex A))	-
33685	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33687	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC2:CI-994)	-
33689	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC3:CI-994)	-
33691	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33693	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109316	3066	-	HDAC2	HD2|RPD3|YAF1	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC2:CI-994)	-
33695	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC3:CI-994)	-
33698	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	degradation	target	Baker IM (2023)	35948047	256640	10811	Bivalent ligand 582	JPS026|bivalent_ligand_582	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JPS026 (IAP:IAP ligand ---HDAC1:CI-994)	-
33707	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2021)	34586829	254522	10813	Bivalent ligand 584	MS67|bivalent_ligand_584	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	target	Standardized BVL Name: MS67 (VHL:VHL-1-Me --- WDR5:OICR-9429)	-
33709	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yu X (2023)	38019706	254524	10814	Bivalent ligand 585	MS132/Compound 11|bivalent_ligand_585	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	target	Standardized BVL Name: MS132 (VHL:VHL-1 --- WDR5:precursor 2 (OICR-9429 derivative))	-
33712	116272	11091	-	WDR5	BIG-3|CFAP89|SWD3	9606	Homo sapiens	degradation	target	Yu X (2023)	38019706	254524	10815	Bivalent ligand 586	Compound 25|bivalent_ligand_586	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 25 (CRBN:-oxyacetamide bridged pomalidomide --- WDR5:OICR-9429)	-
33713	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang W (2021)	33859747	254525	10816	Bivalent ligand 587	C004019|bivalent_ligand_587	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110308	4137	-	MAPT	DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU	9606	Homo sapiens	target	Standardized BVL Name: C004019 (VHL:VH032 --- tau:triazole-based tau binder moiety)	-
33716	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK4:Palbociclib)	-
33718	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Wu X (2021)	34568836	254526	10817	Bivalent ligand 588	MS140|bivalent_ligand_588	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS140 (CRBN:pomalidomide --- CDK6:Palbociclib)	-
33720	109346	3099	-	HK2	HKII|HXK2	9606	Homo sapiens	degradation	target	Sang R (2023)	37376788	254527	10818	Bivalent ligand 589	C-02|bivalent_ligand_589	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: C-02 (CRBN:Thalidomide --- HK2:lonidamine)	-
33725	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	LegaardAndersson J (2023)	37807669	254535	10821	Bivalent ligand 600	Compound 3|bivalent_ligand_600	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113306	7468	RP11-262P20.3	WHSC1	MMSET|NSD2|REIIBP|TRX5|WHS	9606	Homo sapiens	target	Standardized BVL Name: compound 3 (VHL:VHL4 --- NSD2:DEL140 compound 1)	-
33727	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Pan P (2023)	37751283	254536	10822	Bivalent ligand 601	PPM-3|bivalent_ligand_601	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111584	5598	-	MAPK7	BMK1|ERK4|ERK5|PRKM7	9606	Homo sapiens	target	Standardized BVL Name: PPM-3 (VHL:VH032 --- ERK5:XMD8-92)	-
33734	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Basu AA (2024)	38965383	254538	10825	Bivalent ligand 604	22-JQ1|bivalent_ligand_604	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 22-JQ1 (FBXO22:22 --- BRD4:JQ1)	-
33739	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Castellani B (2023)	37699425	254593	10828	Bivalent ligand 607	Compound 9|bivalent_ligand_607	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106862	367	RP11-383C12.1	AR	AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM	9606	Homo sapiens	target	Standardized BVL Name: Compound 9 (VHL:MTX-23 CRL2VHL ligand derivative --- AR:AR DBD binding molecule)	-
33741	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Fan H (2023)	37683536	254595	10829	Bivalent ligand 608	precursor 1a|bivalent_ligand_608	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: precursor 1a (VHL:VHL Ligand with GSH-responsive capping group --- BRD4:JQ1)	-
33748	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	degradation	target	Chen Z (2023)	37647546	254601	10832	Bivalent ligand 611	ERD-3111|bivalent_ligand_611	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ERD-3111 (CRBN:TX-16 --- ESRA:lasofoxifene)	-
33765	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhao C (2023)	37638390	254605	10841	Bivalent ligand 620	P7|bivalent_ligand_620	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: P7 (VHL:VHL-021 --- HDAC3:16 (BRD3308 derivative))	-
33767	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10842	Bivalent ligand 621	Comp-K|bivalent_ligand_621	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-K (VHL:VH032 --- CypA:2d (CypA-L1))	-
33769	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10843	Bivalent ligand 622	Comp-L|bivalent_ligand_622	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-L (VHL:VH032 --- CypA:2d (CypA-L1))	-
33771	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li H (2023)	37636080	254606	10844	Bivalent ligand 623	Comp-M|bivalent_ligand_623	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111474	5478	-	PPIA	CYPA|CYPH|HEL-S-69p	9606	Homo sapiens	target	Standardized BVL Name: Comp-M (VHL:VH032 --- CypA:3c (CypA-L2))	-
33774	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK4:palbociclib)	-
33776	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10845	Bivalent ligand 624	BSJ-02-162|bivalent_ligand_624	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-02-162 (CRBN:pomalidomide --- CDK6:palbociclib)	-
33778	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10846	Bivalent ligand 625	FN-POM|bivalent_ligand_625	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FN-POM (CRBN:pomalidomide --- CDK2:N-1501)	-
33781	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Wang L (2024)	38334978	254612	10848	Bivalent ligand 627	NR-V04|bivalent_ligand_627	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109407	3164	-	NR4A1	GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3	9606	Homo sapiens	target	Standardized BVL Name: NR-V04 (VHL:VHL-032 --- NR4A1:celastrol)	-
33783	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li C (2023)	37605297	254613	10849	Bivalent ligand 628	PIK5-12d|bivalent_ligand_628	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	128336	200576	-	PIKFYVE	CFD|FAB1|HEL37|PIP5K|PIP5K3|ZFYVE29	9606	Homo sapiens	target	Standardized BVL Name: PIK5-12d (VHL:VHL Ligand --- PIKfyve:apilimod)	-
33787	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2023)	37572669	254616	10851	Bivalent ligand 630	YX968 (25)|bivalent_ligand_630	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114368	8841	-	HDAC3	HD3|RPD3|RPD3-2	9606	Homo sapiens	target	Standardized BVL Name: YX968 (25) (VHL:VHL-021 --- HDAC3:Compound 15)	-
33789	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xiao Y (2023)	37572669	254616	10851	Bivalent ligand 630	YX968 (25)|bivalent_ligand_630	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120968	55869	CDA07	HDAC8	CDLS5|HD8|HDACL1|MRXS6|RPD3|WTS	9606	Homo sapiens	target	Standardized BVL Name: YX968 (25) (VHL:VHL-021 --- HDAC8:Compound 15)	-
33792	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Xie H (2023)	37572533	254628	10852	Bivalent ligand 631	E-3P-MDM2|bivalent_ligand_631	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E-3P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33794	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Xie H (2023)	37572533	254628	10853	Bivalent ligand 632	E-4P-MDM2|bivalent_ligand_632	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E-4P-MDM2 (MDM2:Nutlin-3 --- EZH2:Tazemetostat (EPZ6438))	-
33813	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10860	Bivalent ligand 639	SMD-3040 (29)|bivalent_ligand_639	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: SMD-3040 (29) (VHL:VHL Ligand --- SMARCA2:compound 3)	-
33815	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10861	Bivalent ligand 640	Compound 15|bivalent_ligand_640	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: Compound 15 (VHL:VHL Ligand --- SMARCA2:compound 3)	-
33817	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Yang L (2023)	37523716	254780	10861	Bivalent ligand 640	Compound 15|bivalent_ligand_640	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: Compound 15 (VHL:VHL Ligand --- SMARCA4:compound 3)	-
33819	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cantley J (2022)	36357397	254785	10862	Bivalent ligand 641	A947|bivalent_ligand_641	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: A947 (VHL:VHL Ligand --- SMARCA2:SMARCA2/4/PBRM1 Ligand)	-
33821	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cantley J (2022)	36357397	254785	10862	Bivalent ligand 641	A947|bivalent_ligand_641	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112481	6597	-	SMARCA4	BAF190|BAF190A|BRG1|MRD16|RTPS2|SNF2|SNF2L4|SNF2LB|SWI2|hSNF2b	9606	Homo sapiens	target	Standardized BVL Name: A947 (VHL:VHL Ligand --- SMARCA4:SMARCA2/4/PBRM1 Ligand)	-
33823	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Kofink C (2022)	36216795	254788	10863	Bivalent ligand 642	ACBI2|bivalent_ligand_642	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112479	6595	-	SMARCA2	BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a	9606	Homo sapiens	target	Standardized BVL Name: ACBI2 (VHL:VHL ligand VH101 --- SMARCA2:SMARCA2/4/PBRM1 binder compound 3)	-
33830	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Bockstiegel J (2023)	37481141	254804	10866	Bivalent ligand 645	A6|bivalent_ligand_645	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC6:pan-HDAC inhibitor SAHA)	-
33833	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Gui W (2023)	37449865	254807	10868	Bivalent ligand 647	WJ662|bivalent_ligand_647	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	target	Standardized BVL Name: WJ662 (VHL:VH 032 --- VHL:VH 032)	-
33835	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Valdivia A (2023)	37449845	254808	10869	Bivalent ligand 648	Compound 11|bivalent_ligand_648	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112910	7052	RP5-1054A22.2	TGM2	G-ALPHA-h|GNAH|HEL-S-45|TG2|TGC	9606	Homo sapiens	target	Standardized BVL Name: Compound 11 (VHL:VH032 --- TG2:MT4)	-
33837	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Valdivia A (2023)	37449845	254808	10870	Bivalent ligand 649	Compound 7|bivalent_ligand_649	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112910	7052	RP5-1054A22.2	TGM2	G-ALPHA-h|GNAH|HEL-S-45|TG2|TGC	9606	Homo sapiens	target	Standardized BVL Name: Compound 7 (VHL:VH032 --- TG2:MT4)	-
33854	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Bagka M (2023)	37393376	254824	10875	Bivalent ligand 654	HPP-9|bivalent_ligand_654	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HPP-9 (CRBN:Hydroxythalidomide --- BRD4:HPI-1)	-
33859	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang P (2023)	37369332	254853	10878	Bivalent ligand 657	compound C5|bivalent_ligand_657	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115438	10135	-	NAMPT	1110035O14Rik|PBEF|PBEF1|VF|VISFATIN	9606	Homo sapiens	target	Standardized BVL Name: compound C5 (VHL:VHL ligand 2 --- NAMPT:FK866)	-
33864	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Ody BK (2023)	37625128	254777	10880	Bivalent ligand 659	HaloPROTAC-4b|bivalent_ligand_659	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-4b (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33866	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Ody BK (2023)	37625128	254777	10881	Bivalent ligand 660	HaloPROTAC-5c|bivalent_ligand_660	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HaloPROTAC-5c (CRBN:pomalidomide --- EGFR:EGFP-HaloTag2)	-
33867	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ody BK (2023)	37625128	254777	10882	Bivalent ligand 661	HaloPROTAC-3|bivalent_ligand_661	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: HaloPROTAC-3 (VHL:degradation moiety B --- EGFR:EGFP-HaloTag2)	-
33874	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10885	Bivalent ligand 664	14|bivalent_ligand_664	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 14 (CRBN:pomalidomide --- BRD4:JQ1)	-
33876	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10886	Bivalent ligand 665	15|bivalent_ligand_665	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 15 (CRBN:pomalidomide --- BRD4:JQ1)	-
33878	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10887	Bivalent ligand 666	16|bivalent_ligand_666	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 16 (CRBN:pomalidomide --- BRD4:JQ1)	-
33880	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10888	Bivalent ligand 667	18|bivalent_ligand_667	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 18 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33882	118878	29110	-	TBK1	NAK|T2K	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10889	Bivalent ligand 668	19|bivalent_ligand_668	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 19 (CRBN:pomalidomide --- TBK1:N-[3-[(2-anilino-5-bromopyrimidin-4-yl)amino]propyl]-N-methylcyclobutanecarboxamide)	-
33910	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	degradation	target	Sinatra L (2020)	32780485	256645	10903	Bivalent ligand 682	HDAC PROTAC 4|bivalent_ligand_682	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HDAC PROTAC 4 (CRBN:thalidomide-based ligand ---HDAC1:HAIR D)	-
33912	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Sinatra L (2020)	32780485	256645	10903	Bivalent ligand 682	HDAC PROTAC 4|bivalent_ligand_682	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HDAC PROTAC 4 (CRBN:thalidomide-based ligand ---HDAC1:HAIR D)	-
33914	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Sinatra L (2022)	36473103	256646	10904	Bivalent ligand 683	A6|bivalent_ligand_683	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC6:vorinostat-like HDAC ligand)	-
33916	109315	3065	RP4-811H24.2	HDAC1	GON-10|HD1|RPD3|RPD3L1	9606	Homo sapiens	degradation	target	Sinatra L (2022)	36473103	256646	10904	Bivalent ligand 683	A6|bivalent_ligand_683	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: A6 (CRBN:thalidomide --- HDAC1:vorinostat-like HDAC ligand)	-
33918	115330	10013	JM21	HDAC6	CPBHM|HD6|PPP1R90	9606	Homo sapiens	degradation	target	Sinatra L (2022)	36473103	256646	10905	Bivalent ligand 684	B4|bivalent_ligand_684	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: B4 (CRBN:thalidomide --- HDAC6:benzimidazole-based HDAC6 ligand)	-
33920	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	degradation	target	Liu F (2022)	35652200	256647	10906	Bivalent ligand 685	dAurA383|bivalent_ligand_685	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dAurA383 (CRBN:thalidomide --- AURKA:MLN8237)	-
33921	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Liu F (2022)	35652200	256647	10907	Bivalent ligand 686	dAurA425|bivalent_ligand_686	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAurA425 (VHL:VH032 --- AURKA:MLN8237)	-
33923	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Liu F (2022)	35652200	256647	10908	Bivalent ligand 687	dAurA450|bivalent_ligand_687	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112666	6790	RP5-1167H4.6	AURKA	AIK|ARK1|AURA|AURORA2|BTAK|PPP1R47|STK15|STK6|STK7	9606	Homo sapiens	target	Standardized BVL Name: dAurA450 (cIAP1:cIAP1 ligand --- AURKA:MLN8237)	-
33926	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Wang L (2021)	33664520	256648	10909	Bivalent ligand 688	CPS2|bivalent_ligand_688	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CPS2 (CRBN:pomalidomide --- CDK2:J2)	-
33928	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Jin J (2022)	36509291	256649	10910	Bivalent ligand 689	TSM-1|bivalent_ligand_689	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TSM-1 (CRBN:lenalidomide --- STAT3:Toosendanin)	-
33929	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Si R (2023)	36508995	256650	10911	Bivalent ligand 690	SV|bivalent_ligand_690	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111185	5159	-	PDGFRB	CD140B|IBGC4|IMF1|JTK12|PDGFR|PDGFR-1|PDGFR1	9606	Homo sapiens	target	Standardized BVL Name: SV (VHL:VH032 --- PDGFRB:sorafenib)	-
33938	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chen J (2022)	35395439	256652	10915	Bivalent ligand 694	7f|bivalent_ligand_694	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 7f (CRBN:pomalidomide --- BRD4:ABBV-744)	-
33940	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chen J (2022)	35395439	256652	10916	Bivalent ligand 695	13d|bivalent_ligand_695	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 13d (CRBN:pomalidomide ---BRD4:ABBV-744)	-
33943	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Du G (2021)	33915015	255461	10918	Bivalent ligand 697	DGY-09-192|bivalent_ligand_697	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108551	2260	-	FGFR1	BFGFR|CD331|CEK|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1	9606	Homo sapiens	target	Standardized BVL Name: DGY-09-192 (VHL:VHL ligand --- FGFR1:BGJ398)	-
33945	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Du G (2021)	33915015	255461	10918	Bivalent ligand 697	DGY-09-192|bivalent_ligand_697	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108554	2263	-	FGFR2	BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25	9606	Homo sapiens	target	Standardized BVL Name: DGY-09-192 (VHL:VHL ligand --- FGFR2:BGJ398)	-
33948	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	degradation	target	Zhou H (2021)	34141084	255462	10919	Bivalent ligand 698	SD-91|bivalent_ligand_698	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SD-91 (CRBN:lenalidomide --- STAT3:SI-191)	-
33949	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhang H (2022)	35178183	255463	10920	Bivalent ligand 699	Compound 6h|bivalent_ligand_699	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	target	Standardized BVL Name: Compound 6h (VHL:VHL ligand --- EGFR Del19/T790M/C797S:brigatinib analog 3)	-
33970	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	degradation	target	Shi W (2022)	35279611	255470	10930	Bivalent ligand 709	compound 20|bivalent_ligand_709	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 20 (CRBN:lenalidomide --- AXL:R428 derivative)	-
33972	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	degradation	target	Shi W (2022)	35279611	255470	10931	Bivalent ligand 710	compound 22|bivalent_ligand_710	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 22 (CRBN:lenalidomide --- AXL:R428 derivative)	-
33981	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hati S (2021)	34560429	255476	10936	Bivalent ligand 715	PROTAC-8|bivalent_ligand_715	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	target	Standardized BVL Name: PROTAC-8 (VHL:VH032 --- CDK2:AZD5438)	-
33983	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10937	Bivalent ligand 716	Halo-PROTAC 3|bivalent_ligand_716	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117422	25921	-	ZDHHC5	DHHC5|ZNF375	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 3 (VHL:VH032 --- zDHHC5:Halo-zDHHC5)	-
33985	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10938	Bivalent ligand 717	Halo-PROTAC 1|bivalent_ligand_717	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	117422	25921	-	ZDHHC5	DHHC5|ZNF375	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 1 (VHL:fluorocyclopropane-containing VHL-targeting ligand --- zDHHC5:Halo-zDHHC5)	-
33989	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10937	Bivalent ligand 716	Halo-PROTAC 3|bivalent_ligand_716	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	128991	253832	-	ZDHHC20	4933421L13Rik|DHHC-20	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 3 (VHL:VH032 --- zDHHC20:Halo-zDHHC20)	-
33991	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bai M (2024)	38512906	255477	10938	Bivalent ligand 717	Halo-PROTAC 1|bivalent_ligand_717	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	HaloPROTAC	PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	128991	253832	-	ZDHHC20	4933421L13Rik|DHHC-20	9606	Homo sapiens	target	Standardized BVL Name: Halo-PROTAC 1 (VHL:fluorocyclopropane-containing VHL-targeting ligand --- zDHHC20:Halo-zDHHC20)	-
33999	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Li N (2025)	40045307	256655	10942	Bivalent ligand 721	KT-333|bivalent_ligand_721	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112651	6774	-	STAT3	ADMIO|APRF|HIES	9606	Homo sapiens	target	Standardized BVL Name: KT-333 (VHL:VHL ligand --- STAT3:undisclosed)	-
34006	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Pei J (2021)	34816823	256657	10945	Bivalent ligand 724	10f|bivalent_ligand_724	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: 10f (MAP1LC3B:GW5074 --- BRD4:JQ1)	-
34008	113265	7422	RP1-261G23.1	VEGFA	MVCD1|VEGF|VPF	9606	Homo sapiens	degradation	target	Zhou P (2024)	39267779	256658	10946	Bivalent ligand 725	V5|bivalent_ligand_725	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	109703	3482	-	IGF2R	CD222|CIMPR|M6P-R|MPR1|MPRI	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: V5 (IGF2R:M6PR-A --- VEGF:VEGF-A2)	-
34010	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Du J (2024)	38910165	256659	10947	Bivalent ligand 726	OEGMA10-BMS-110-GalMA10|bivalent_ligand_726	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	106924	432	-	ASGR1	ASGPR|ASGPR1|CLEC4H1|HL-1	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: OEGMA10-BMS-110-GalMA10 (ASGR1:GalMA --- CD274:BMS-1)	-
34012	118891	29126	-	CD274	B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1	9606	Homo sapiens	degradation	target	Du J (2024)	38910165	256659	10948	Bivalent ligand 727	OEGMA10-CP10-GalMA10|bivalent_ligand_727	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	LYTAC	Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	106924	432	-	ASGR1	ASGPR|ASGPR1|CLEC4H1|HL-1	9606	Homo sapiens	lysosome-targeting protein	Standardized BVL Name: OEGMA10-CP10-GalMA10 (ASGR1:GalMA --- CD274:cycloPep)	-
34044	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2021)	34432252	256663	10957	Bivalent ligand 736	PHOTAC-I-3|bivalent_ligand_736	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
34048	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2021)	34432252	256663	10958	Bivalent ligand 737	PHOTAC-I-10|bivalent_ligand_737	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-10 (CRBN:thalidomide --- BRD4:JQ1)	-
34053	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10961	Bivalent ligand 740	MS928|bivalent_ligand_740	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS928 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34055	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10961	Bivalent ligand 740	MS928|bivalent_ligand_740	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS928 (VHL:VHL-1 --- MAP2K2:PD0325901)	-
34057	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10962	Bivalent ligand 741	MS934|bivalent_ligand_741	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	target	Standardized BVL Name: MS934 (VHL:VHL-1 --- MAP2K1:PD0325901)	-
34059	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Hu J (2020)	33284613	256664	10962	Bivalent ligand 741	MS934|bivalent_ligand_741	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	target	Standardized BVL Name: MS934 (VHL:VHL-1 --- MAP2K2:PD0325901)	-
34062	111590	5604	-	MAP2K1	CFC3|MAPKK1|MEK1|MKK1|PRKMK1	9606	Homo sapiens	degradation	target	Hu J (2020)	33284613	256664	10963	Bivalent ligand 742	MS910|bivalent_ligand_742	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS910 (CRBN:pomalidomide --- MAP2K1:PD0325901)	-
34064	111591	5605	-	MAP2K2	CFC4|MAPKK2|MEK2|MKK2|PRKMK2	9606	Homo sapiens	degradation	target	Hu J (2020)	33284613	256664	10963	Bivalent ligand 742	MS910|bivalent_ligand_742	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS910 (CRBN:pomalidomide --- MAP2K2:PD0325901)	-
34066	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- EZH2:EPZ6438)	-
34072	111863	5928	-	RBBP4	NURF55|RBAP48|lin-53	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- RBBP4:EPZ6438)	-
34073	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10965	Bivalent ligand 744	compound 8|bivalent_ligand_744	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 8 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34075	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10966	Bivalent ligand 745	compound 9|bivalent_ligand_745	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 9 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34077	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10967	Bivalent ligand 746	compound 12|bivalent_ligand_746	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 12 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34079	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dragovich PS (2021)	33596073	256666	10968	Bivalent ligand 747	compound 13|bivalent_ligand_747	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	target	Standardized BVL Name: compound 13 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34087	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EED:EED226)	-
34089	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---EZH2:EED226)	-
34091	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10972	Bivalent ligand 751	UNC7700|bivalent_ligand_751	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC7700 (VHL:VH032-amine ---SUZ12:EED226)	-
34093	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EED:EED226)	-
34095	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108446	2146	-	EZH2	ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---EZH2:EED226)	-
34097	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10973	Bivalent ligand 752	UNC7327|bivalent_ligand_752	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117059	23512	-	SUZ12	CHET9|JJAZ1	9606	Homo sapiens	target	Standardized BVL Name: UNC7327 (VHL:VH032-amine ---SUZ12:EED226)	-
34099	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Bashore FM (2023)	36877831	256669	10974	Bivalent ligand 753	UNC7698|bivalent_ligand_753	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: UNC7698 (VHL:VH032-amine ---EED:EED226)	-
34114	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kim SA (2019)	30684871	220042	10977	Bivalent ligand 756	TD-428|bivalent_ligand_756	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TD-428 (CRBN:TD-106 --- BRD4:JQ1)	-
34118	111719	5747	-	PTK2	FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|pp125FAK	9606	Homo sapiens	degradation	target	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- FAK:YHJ1039)	-
34120	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK4:YHJ1039)	-
34122	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Kim Y (2023)	37567174	256416	10978	Bivalent ligand 757	KYH1872/Compound 26|bivalent_ligand_757	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117123	23588	-	KLHDC2	HCLP-1|HCLP1|LCP	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: KYH1872 (KLHDC2:SelK peptide --- CDK6:YHJ1039)	-
34125	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Wen T (2023)	37298935	256429	10979	Bivalent ligand 758	Compound 5|bivalent_ligand_758	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112506	6622	-	SNCA	NACP|PARK1|PARK4|PD1	9606	Homo sapiens	target	Standardized BVL Name: Compound 5 (cIAP1 :bestatin --- SNCA:sery384)	-
34130	115956	10733	-	PLK4	SAK|STK18	9606	Homo sapiens	degradation	target	Sun Y (2023)	37279162	256430	10981	Bivalent ligand 760	SP27|bivalent_ligand_760	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SP27 (CRBN:thalidomide --- PLK4:CZS-035)	-
34132	107454	1019	-	CDK4	CMM3|PSK-J3	9606	Homo sapiens	degradation	target	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK4:Palbociclib)	-
34134	107456	1021	-	CDK6	MCPH12|PLSTIRE	9606	Homo sapiens	degradation	target	Pu C (2023)	37276679	256431	10982	Bivalent ligand 761	compound A4|bivalent_ligand_761	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound A4 (DCAF16:KB02 --- CDK6:Palbociclib)	-
34143	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cai M (2023)	37257255	256438	10986	Bivalent ligand 765	GDC-22|bivalent_ligand_765	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	109137	2879	-	GPX4	GPx-4|GSHPx-4|MCSP|PHGPx|snGPx|snPHGPx	9606	Homo sapiens	target	Standardized BVL Name: GDC-22 (VHL:VHL Ligand --- GPX4:ML162-1)	-
34148	109187	2932	-	GSK3B	-	9606	Homo sapiens	degradation	target	Guardigni M (2023)	37218653	256440	10988	Bivalent ligand 767	Compound 1|bivalent_ligand_767	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 1 (CRBN:pomalidomide --- GSK3B:SB-216763)	-
34163	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10992	Bivalent ligand 771	UNC9036|bivalent_ligand_771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC9036 (VHL:VH032 --- STING:diABZI compound 3)	-
34165	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10993	Bivalent ligand 772	UNC8899|bivalent_ligand_772	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC8899 (VHL:VH032 --- STING:diABZI compound 3)	-
34167	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhu Z (2023)	37183204	256444	10994	Bivalent ligand 773	UNC8900|bivalent_ligand_773	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	130988	340061	-	TMEM173	ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING	9606	Homo sapiens	target	Standardized BVL Name: UNC8900 (VHL:VH032 --- STING:diABZI compound 3)	-
34175	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37163809	256447	10997	Bivalent ligand 776	PROTAC 8a|bivalent_ligand_776	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: PROTAC 8a (VHL:VHL ligand --- ESR1:OBHSA)	-
34177	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	10998	Bivalent ligand 777	ZD12|bivalent_ligand_777	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD12 (VHL:VHL ligand --- ESR1:OBHSA)	-
34179	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	10999	Bivalent ligand 778	ZD11|bivalent_ligand_778	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD11 (VHL:VHL ligand --- ESR1:OBHSA)	-
34181	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	11000	Bivalent ligand 779	ZD8|bivalent_ligand_779	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD8 (VHL:VHL ligand --- ESR1:OBHSA)	-
34183	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Xie B (2023)	37161783	256448	11001	Bivalent ligand 780	ZD2|bivalent_ligand_780	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	108403	2099	RP1-130E4.1	ESR1	ER|ESR|ESRA|ESTRR|Era|NR3A1	9606	Homo sapiens	target	Standardized BVL Name: ZD2 (VHL:VHL ligand --- ESR1:OBHSA)	-
34193	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2023)	37094179	256453	11006	Bivalent ligand 785	DeFer-2|bivalent_ligand_785	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199759	14325	-	Ftl1	Ftl|Ftl-1|L-ferritin	10090	Mus musculus	target	Standardized BVL Name: DeFer-2 (VHL:VH032 --- FTL:oleic acid)	-
34195	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Chen Y (2023)	37094179	256453	11006	Bivalent ligand 785	DeFer-2|bivalent_ligand_785	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	199755	14319	-	Fth1	FHC|Fth|HFt|MFH	10090	Mus musculus	target	Standardized BVL Name: DeFer-2 (VHL:VH032 --- FTH1:oleic acid)	-
34205	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	recruited e3 ligase	Wang W (2023)	37002536	256462	11011	Bivalent ligand 790	Compound 13|bivalent_ligand_790	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	201282	17133	-	Maff	-	10090	Mus musculus	target	Standardized BVL Name: Compound 13 (cIAP1:bestatin --- MAFF:lathyrol)	-
34209	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- cIAP1:CST530)	-
34211	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- cIAP2:CST530)	-
34213	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Ng YLD (2023)	36996313	256472	11013	Bivalent ligand 792	hetero-PROTAC 9|bivalent_ligand_792	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	target	Standardized BVL Name: hetero-PROTAC 9 (VHL:Me-VHL1 --- XIAP:CST530)	-
34216	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	degradation	target	Ng YLD (2023)	36996313	256472	11014	Bivalent ligand 793	hetero-PROTAC 25|bivalent_ligand_793	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: hetero-PROTAC 25 (CRBN:thalidomide --- cIAP1:CST530)	-
34218	106827	330	-	BIRC3	AIP1|API2|CIAP2|HAIP1|HIAP1|MALT2|MIHC|RNF49|c-IAP2	9606	Homo sapiens	degradation	target	Ng YLD (2023)	36996313	256472	11014	Bivalent ligand 793	hetero-PROTAC 25|bivalent_ligand_793	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: hetero-PROTAC 25 (CRBN:thalidomide --- cIAP2:CST530)	-
34223	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dong J (2023)	36973833	256473	11016	Bivalent ligand 795	DU-14|bivalent_ligand_795	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111736	5770	-	PTPN1	PTP1B	9606	Homo sapiens	target	Standardized BVL Name: DU-14 (VHL:(S,R,S)-AHPC-Me --- PTP1B:DI-03)	-
34225	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Dong J (2023)	36973833	256473	11016	Bivalent ligand 795	DU-14|bivalent_ligand_795	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111737	5771	-	PTPN2	PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP	9606	Homo sapiens	target	Standardized BVL Name: DU-14 (VHL:(S,R,S)-AHPC-Me --- TC-PTP:DI-03)	-
34228	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	degradation	target	Son SH (2023)	36968534	256474	11017	Bivalent ligand 796	PRZ-18002|bivalent_ligand_796	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PRZ-18002 (CRBN:pomalidomide --- MAPK14:p-p38 ligand)	-
34240	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2023)	36906965	256503	11023	Bivalent ligand 801	ha-PROTAC 9|bivalent_ligand_801	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 9 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34242	108276	1956	-	EGFR	ERBB|ERBB1|HER1|NISBD2|PIG61|mENA	9606	Homo sapiens	degradation	target	Cheng W (2023)	36906965	256503	11024	Bivalent ligand 802	ha-PROTAC 10|bivalent_ligand_802	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ha-PROTAC 10 (CRBN:HALG-lenalidomide --- EGFRDel19:target ligand)	-
34243	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Teng M (2023)	36898968	256504	11025	Bivalent ligand 803	TMX-4153|bivalent_ligand_803	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	122928	79837	-	PIP4K2C	PIP5K2C	9606	Homo sapiens	target	Standardized BVL Name: TMX-4153 (VHL:VHL ligand --- PIP4K2C:TMX-4140 )	-
34245	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Zhou Z (2023)	36897932	256505	11026	Bivalent ligand 804	ZZ151|bivalent_ligand_804	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	112537	6654	-	SOS1	GF1|GGF1|GINGF|HGF|NS4	9606	Homo sapiens	target	Standardized BVL Name: ZZ151 (VHL:VHL ligand --- SOS1:BI-3406)	-
34260	112592	6714	RP5-823N20.1	SRC	ASV|SRC1|c-SRC|p60-Src	9606	Homo sapiens	degradation	target	Hu J (2022)	36001679	256518	11031	Bivalent ligand 809	SJ11646|bivalent_ligand_809	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SJ11646 (CRBN:phenyl glutarimide (PG) --- SRC:dasatinib)	-
34261	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Cubillos-Rojas M (2023)	36765568	256520	11032	Bivalent ligand 810	NR-11c|bivalent_ligand_810	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107819	1432	RP1-179N16.5	MAPK14	CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA	9606	Homo sapiens	target	Standardized BVL Name: NR-11c (VHL:VHL ligand --- MAPK14:PH-797804)	-
34269	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	107116	648	RP11-573G6.1	BMI1	FLVI2/BMI1|PCGF4|RNF51	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- BMI1:EED226)	-
34271	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111972	6045	GS1-120K12.1	RNF2	BAP-1|BAP1|DING|HIPI3|RING1B|RING2	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- RING1B:EED226)	-
34273	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	degradation	recruited e3 ligase	Park KS (2023)	36737841	256522	11035	Bivalent ligand 813	MS147|bivalent_ligand_813	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	114265	8726	-	EED	HEED|WAIT1	9606	Homo sapiens	target	Standardized BVL Name: MS147 (VHL:VHL1 --- EED:EED226)	-
34278	112654	6777	-	STAT5B	STAT5	9606	Homo sapiens	degradation	target	Kaneshige A (2023)	36735833	256523	11036	Bivalent ligand 814	AK-2292|bivalent_ligand_814	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: AK-2292 (CRBN:lenalidomide analogue --- STAT5B:phosphotyrosine mimetic STAT5/6 inhibitor 12)	-
34282	107036	558	-	AXL	ARK|JTK11|Tyro7|UFO	9606	Homo sapiens	degradation	target	He R (2023)	36695404	256526	11038	Bivalent ligand 816	compound 6n|bivalent_ligand_816	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 6n (CRBN:lenalidomide --- AXL:HH30134 analogue 9im)	-
