#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P52294	uniprotkb:Q86WI3	intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93	intact:EBI-2677060|uniprotkb:B5MEF1|uniprotkb:C9JMD8|uniprotkb:Q6P4A6|uniprotkb:Q86VM7|uniprotkb:Q8NF42|uniprotkb:Q8TEE2|uniprotkb:Q8TEJ1|uniprotkb:Q969L7|ensembl:ENSP00000262510	psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym)	psi-mi:nlrc5_human(display_long)|uniprotkb:NLRC5(gene name)|psi-mi:NLRC5(display_short)|uniprotkb:NOD27(gene name synonym)|uniprotkb:NOD4(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 4(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 27(gene name synonym)|uniprotkb:Caterpiller protein 16.1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yoo et al. (2021)	pubmed:34782627|imex:IM-29388	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-28951938|imex:IM-29388-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1	refseq:XP_011521675.1|refseq:NP_115582.4|refseq:XP_005256250.1|refseq:XP_005256251.1|refseq:XP_005256254.1|ensembl:ENSG00000140853(gene)|ensembl:ENST00000262510(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041210|interpro:IPR041267|mint:Q86WI3|reactome:R-HSA-168928|reactome:R-HSA-936440|refseq:XP_006721360.1|refseq:NP_001317481.1	-	-	-	figure legend:6 B/E|comment:ORF6 did not interfere with this interaction.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/12/13	2021/12/15	rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606	rogid:9tBKwZ2Nwm7n7F2gaSLxhmCa+w49606	rigid:5vdfmWCdrsHyVt5pXquXVS7lxB4	false	green fluorescent protein tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60684	uniprotkb:Q86WI3	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-2677060|uniprotkb:B5MEF1|uniprotkb:C9JMD8|uniprotkb:Q6P4A6|uniprotkb:Q86VM7|uniprotkb:Q8NF42|uniprotkb:Q8TEE2|uniprotkb:Q8TEJ1|uniprotkb:Q969L7|ensembl:ENSP00000262510	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:nlrc5_human(display_long)|uniprotkb:NLRC5(gene name)|psi-mi:NLRC5(display_short)|uniprotkb:NOD27(gene name synonym)|uniprotkb:NOD4(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 4(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 27(gene name synonym)|uniprotkb:Caterpiller protein 16.1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yoo et al. (2021)	pubmed:34782627|imex:IM-29388	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-28951946|imex:IM-29388-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	refseq:XP_011521675.1|refseq:NP_115582.4|refseq:XP_005256250.1|refseq:XP_005256251.1|refseq:XP_005256254.1|ensembl:ENSG00000140853(gene)|ensembl:ENST00000262510(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|interpro:IPR041210|interpro:IPR041267|mint:Q86WI3|reactome:R-HSA-168928|reactome:R-HSA-936440|refseq:XP_006721360.1|refseq:NP_001317481.1	-	-	-	figure legend:6 B/E|comment:ORF6 did not interfere with this interaction.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/12/13	2021/12/15	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:9tBKwZ2Nwm7n7F2gaSLxhmCa+w49606	rigid:1EaNyNnJIS6CNHMeFxzZT390ukM	false	green fluorescent protein tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)