#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H313 uniprotkb:Q9H313 intact:EBI-20793786|uniprotkb:B0VJY3|uniprotkb:B0VJY4|uniprotkb:B0VJY5|uniprotkb:B2VAL9|uniprotkb:Q5U682|uniprotkb:Q68A17|uniprotkb:Q6L750|uniprotkb:Q6ZTE5|uniprotkb:Q8WUU2|ensembl:ENSP00000365713|ensembl:ENSP00000480769|ensembl:ENSP00000481138|ensembl:ENSP00000484774 intact:EBI-20793786|uniprotkb:B0VJY3|uniprotkb:B0VJY4|uniprotkb:B0VJY5|uniprotkb:B2VAL9|uniprotkb:Q5U682|uniprotkb:Q68A17|uniprotkb:Q6L750|uniprotkb:Q6ZTE5|uniprotkb:Q8WUU2|ensembl:ENSP00000365713|ensembl:ENSP00000480769|ensembl:ENSP00000481138|ensembl:ENSP00000484774 psi-mi:ttyh1_human(display_long)|uniprotkb:TTYH1(gene name)|psi-mi:TTYH1(display_short) psi-mi:ttyh1_human(display_long)|uniprotkb:TTYH1(gene name)|psi-mi:TTYH1(display_short) psi-mi:"MI:0410"(3D electron microscopy) Sukalskaia et al. (2021) imex:IM-29273|pubmed:34385445 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-27096538|imex:IM-29273-1|wwpdb:7P5J|emdb:EMD-13200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005367.1|refseq:NP_001188390.1|refseq:NP_065710.1|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|mint:Q9H313|reactome:R-HSA-2672351|ensembl:ENSG00000167614(gene)|ensembl:ENSG00000275650(gene)|ensembl:ENSG00000276537(gene)|ensembl:ENSG00000276887(gene)|ensembl:ENST00000376530(transcript)|ensembl:ENST00000611711(transcript)|ensembl:ENST00000619450(transcript)|ensembl:ENST00000620298(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006826"(iron ion transport) refseq:NP_001005367.1|refseq:NP_001188390.1|refseq:NP_065710.1|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|mint:Q9H313|reactome:R-HSA-2672351|ensembl:ENSG00000167614(gene)|ensembl:ENSG00000275650(gene)|ensembl:ENSG00000276537(gene)|ensembl:ENSG00000276887(gene)|ensembl:ENST00000376530(transcript)|ensembl:ENST00000611711(transcript)|ensembl:ENST00000619450(transcript)|ensembl:ENST00000620298(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006826"(iron ion transport) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293s_gnti)|taxid:9606(HEK293S GnTI -adenovirus 5 transformed, glycosylation deficient) - 2021/09/29 2021/09/30 rogid:iaivv85TtJGcZfrVUIFCs8YThuU9606 rogid:iaivv85TtJGcZfrVUIFCs8YThuU9606 rigid:lSHMAJdeAQE8XmaVwAu2MHHcFdE false - - 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q9BSA4 uniprotkb:Q9BSA4 intact:EBI-3959652|uniprotkb:Q3B7H8|uniprotkb:Q6AWB4|uniprotkb:Q96PK1|uniprotkb:B3KX97|uniprotkb:Q3B7R9|uniprotkb:Q8NBB7|ensembl:ENSP00000269346 intact:EBI-3959652|uniprotkb:Q3B7H8|uniprotkb:Q6AWB4|uniprotkb:Q96PK1|uniprotkb:B3KX97|uniprotkb:Q3B7R9|uniprotkb:Q8NBB7|ensembl:ENSP00000269346 psi-mi:ttyh2_human(display_long)|uniprotkb:TTYH2(gene name)|psi-mi:TTYH2(display_short)|uniprotkb:C17orf29(gene name synonym) psi-mi:ttyh2_human(display_long)|uniprotkb:TTYH2(gene name)|psi-mi:TTYH2(display_short)|uniprotkb:C17orf29(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sukalskaia et al. (2021) imex:IM-29273|pubmed:34385445 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-27096608|wwpdb:7P54|emdb:EMD-13194|wwpdb:7P5M|emdb:EMD-13201|imex:IM-29273-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116035.5|refseq:NP_443101.1|ensembl:ENSG00000141540(gene)|ensembl:ENST00000269346(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|reactome:R-HSA-2672351|ensembl:ENSP00000269346|ensembl:ENST00000441391|ensembl:ENSP00000394576 refseq:NP_116035.5|refseq:NP_443101.1|ensembl:ENSG00000141540(gene)|ensembl:ENST00000269346(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|reactome:R-HSA-2672351|ensembl:ENSP00000269346|ensembl:ENST00000441391|ensembl:ENSP00000394576 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293s_gnti)|taxid:9606(HEK293S GnTI -adenovirus 5 transformed, glycosylation deficient) - 2021/09/29 2021/09/30 rogid:l8Isu7SO6u8WrtbQIwcx4R1waMk9606 rogid:l8Isu7SO6u8WrtbQIwcx4R1waMk9606 rigid:5/LscwlLUH1MPJDaLLscX9PlMY8 false - - 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q9C0H2 uniprotkb:Q9C0H2 intact:EBI-2116541|uniprotkb:A4D201|uniprotkb:Q6L749|uniprotkb:Q6ZVG3|uniprotkb:Q8TEG6|uniprotkb:B7WP98|ensembl:ENSP00000258796 intact:EBI-2116541|uniprotkb:A4D201|uniprotkb:Q6L749|uniprotkb:Q6ZVG3|uniprotkb:Q8TEG6|uniprotkb:B7WP98|ensembl:ENSP00000258796 psi-mi:ttyh3_human(display_long)|uniprotkb:TTYH3(gene name)|psi-mi:TTYH3(display_short)|uniprotkb:KIAA1691(gene name synonym) psi-mi:ttyh3_human(display_long)|uniprotkb:TTYH3(gene name)|psi-mi:TTYH3(display_short)|uniprotkb:KIAA1691(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sukalskaia et al. (2021) imex:IM-29273|pubmed:34385445 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-27096622|wwpdb:7P5C|emdb:EMD-13198|imex:IM-29273-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011513837.1|refseq:NP_079526.1|refseq:XP_016868145.1|ensembl:ENSP00000258796|ensembl:ENST00000403167|ensembl:ENSP00000385015|ensembl:ENST00000407643|ensembl:ENSP00000385316|ensembl:ENSG00000136295(gene)|ensembl:ENST00000258796(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|reactome:R-HSA-2672351 refseq:XP_011513837.1|refseq:NP_079526.1|refseq:XP_016868145.1|ensembl:ENSP00000258796|ensembl:ENST00000403167|ensembl:ENSP00000385015|ensembl:ENST00000407643|ensembl:ENSP00000385316|ensembl:ENSG00000136295(gene)|ensembl:ENST00000258796(transcript)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072320"(volume-sensitive chloride channel activity)|interpro:IPR006990(Tweety)|reactome:R-HSA-2672351 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293s_gnti)|taxid:9606(HEK293S GnTI -adenovirus 5 transformed, glycosylation deficient) - 2021/09/29 2021/09/30 rogid:zrHCdSE3lMdKNEk2gEqopE6yvNk9606 rogid:zrHCdSE3lMdKNEk2gEqopE6yvNk9606 rigid:f22TEjATADJAMQ8vf37hLImPpWE false - - 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)