#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11226 uniprotkb:P0DTC9 intact:EBI-5325353|ensembl:ENSP00000363079|ensembl:ENSP00000502615|ensembl:ENSP00000502789|uniprotkb:Q4VB12|uniprotkb:Q4VB13|uniprotkb:Q86SI4|uniprotkb:Q96KE4|uniprotkb:Q96TF7|uniprotkb:Q96TF8|uniprotkb:Q96TF9|uniprotkb:Q4VB14|uniprotkb:Q5SQS3 intact:EBI-25475856 psi-mi:mbl2_human(display_long)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym) psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054192|imex:IM-29145-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165471(gene)|ensembl:ENST00000373968(transcript)|ensembl:ENST00000674931(transcript)|ensembl:ENST00000675947(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008228"(opsonization)|go:"GO:0009986"(cell surface)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|refseq:XP_011538118.1|interpro:IPR018378|interpro:IPR033990|interpro:IPR037570|rcsb pdb:1HUP|interpro:IPR016187(C-type lectin fold)|reactome:R-HSA-166662|reactome:R-HSA-166663|refseq:NP_000233.1|refseq:XP_006717924.1|dip:DIP-61381N rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 - - - figure legend:1A, number 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:uo0RM88uw3otObIVnOhUcOfW8yo9606 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rigid:iU2Dlg38H4omt+e3RN1GZeUrsFs false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:28808" uniprotkb:P11226 intact:EBI-25613000|chebi:"CHEBI:6684"|chebi:"CHEBI:25159" intact:EBI-5325353|ensembl:ENSP00000363079|ensembl:ENSP00000502615|ensembl:ENSP00000502789|uniprotkb:Q4VB12|uniprotkb:Q4VB13|uniprotkb:Q86SI4|uniprotkb:Q96KE4|uniprotkb:Q96TF7|uniprotkb:Q96TF8|uniprotkb:Q96TF9|uniprotkb:Q4VB14|uniprotkb:Q5SQS3 psi-mi:mannan(display_short)|psi-mi:"CHEBI:28808"(display_long)|intact:Mannan(synonym)|intact:mannans(synonym)|intact:Mannoglycan(synonym)|intact:mannan(iupac name) psi-mi:mbl2_human(display_long)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054221|imex:IM-29145-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000165471(gene)|ensembl:ENST00000373968(transcript)|ensembl:ENST00000674931(transcript)|ensembl:ENST00000675947(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008228"(opsonization)|go:"GO:0009986"(cell surface)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|refseq:XP_011538118.1|interpro:IPR018378|interpro:IPR033990|interpro:IPR037570|rcsb pdb:1HUP|interpro:IPR016187(C-type lectin fold)|reactome:R-HSA-166662|reactome:R-HSA-166663|refseq:NP_000233.1|refseq:XP_006717924.1|dip:DIP-61381N - - - figure legend:1A, number 3|comment:Positive control|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 - rogid:uo0RM88uw3otObIVnOhUcOfW8yo9606 - false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q15485 uniprotkb:P0DTC9 intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744 intact:EBI-25475856 psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym) psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054644|imex:IM-29145-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 - comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region - figure legend:1B, number 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rigid:Kd6eRrGTD38FRyRwMEvJRsqgIAE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q15485 uniprotkb:P0DTC2 intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744 intact:EBI-25474821 psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym) psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054648|imex:IM-29145-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635 - comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region - figure legend:1B, number 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606 rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049 rigid:QVB0ISCBwKu9vkK+VyrbGVMbFAc false - his tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q15485 uniprotkb:P02769 intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744 intact:EBI-2296927|uniprotkb:A5PJX3|uniprotkb:O02787|uniprotkb:P04277|uniprotkb:Q3SZR2 psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym) psi-mi:albu_bovin(display_long)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:BSA(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054654|imex:IM-29145-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 rcsb pdb:4JK4|refseq:NP_851335.1|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR021177|rcsb pdb:2L7U|rcsb pdb:3V03|rcsb pdb:4F5S|rcsb pdb:4OR0|rcsb pdb:6QS9|rcsb pdb:6RJV|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:1903981"(enterobactin binding) - comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region - figure legend:1B, number 3|comment:Positive control|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606 rogid:J8N23Xjyoe+UM5phxwqJtC2a1+M9913 rigid:oENfdZWAItFDVEGFzw6q1D5AICU false - monoacetylated residue:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9BWP8 uniprotkb:P0DTC9 intact:EBI-25809731|uniprotkb:A1IGE4|uniprotkb:A1IGE5|uniprotkb:A1IGE6|uniprotkb:A7VJJ2|uniprotkb:A7VJJ3|uniprotkb:A7VJJ4|uniprotkb:A7VJJ5|uniprotkb:B2R9M5|uniprotkb:B4E1G0|uniprotkb:J3KQY9|uniprotkb:Q5CZ85|uniprotkb:Q7Z6N1|ensembl:ENSP00000339168 intact:EBI-25475856 psi-mi:col11_human(display_long)|uniprotkb:COLEC11(gene name)|psi-mi:COLEC11(display_short)|uniprotkb:Collectin kidney protein 1(gene name synonym)|uniprotkb:UNQ596/PRO1182(orf name) psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054662|imex:IM-29145-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001242911.1|refseq:NP_001242912.1|refseq:NP_001242913.1|refseq:NP_001242914.1|refseq:NP_001242915.1|refseq:NP_001242916.1|refseq:NP_001242917.1|refseq:NP_001242918.1|refseq:NP_076932.1|refseq:NP_954705.1|interpro:IPR018378|interpro:IPR033990|rcsb pdb:4YLI|rcsb pdb:4YMD|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-3000480|ensembl:ENSG00000118004(gene)|ensembl:ENST00000349077(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0032502"(developmental process)|go:"GO:0042806"(fucose binding)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0120153"(calcium-dependent carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 - - - figure legend:1C, number 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:2tl/YlPmHk+6ScRSkMYFZnOCXjg9606 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rigid:XXaZnz2z6jWSZ/P7G8HIXpmgqnA false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9BWP8 uniprotkb:P0DTC2 intact:EBI-25809731|uniprotkb:A1IGE4|uniprotkb:A1IGE5|uniprotkb:A1IGE6|uniprotkb:A7VJJ2|uniprotkb:A7VJJ3|uniprotkb:A7VJJ4|uniprotkb:A7VJJ5|uniprotkb:B2R9M5|uniprotkb:B4E1G0|uniprotkb:J3KQY9|uniprotkb:Q5CZ85|uniprotkb:Q7Z6N1|ensembl:ENSP00000339168 intact:EBI-25474821 psi-mi:col11_human(display_long)|uniprotkb:COLEC11(gene name)|psi-mi:COLEC11(display_short)|uniprotkb:Collectin kidney protein 1(gene name synonym)|uniprotkb:UNQ596/PRO1182(orf name) psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054666|imex:IM-29145-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001242911.1|refseq:NP_001242912.1|refseq:NP_001242913.1|refseq:NP_001242914.1|refseq:NP_001242915.1|refseq:NP_001242916.1|refseq:NP_001242917.1|refseq:NP_001242918.1|refseq:NP_076932.1|refseq:NP_954705.1|interpro:IPR018378|interpro:IPR033990|rcsb pdb:4YLI|rcsb pdb:4YMD|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-3000480|ensembl:ENSG00000118004(gene)|ensembl:ENST00000349077(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0032502"(developmental process)|go:"GO:0042806"(fucose binding)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0120153"(calcium-dependent carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold) interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635 - - - figure legend:1C, number 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 rogid:2tl/YlPmHk+6ScRSkMYFZnOCXjg9606 rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049 rigid:Rs7+fHEwwu55txsce1n2XaF6Ur4 false - his tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:37671" uniprotkb:Q9BWP8 intact:EBI-27054679|chebi:"CHEBI:530"|chebi:"CHEBI:60750"|chebi:"CHEBI:10800"|chebi:"CHEBI:10802"|chebi:"CHEBI:18294"|chebi:"CHEBI:18922" intact:EBI-25809731|uniprotkb:A1IGE4|uniprotkb:A1IGE5|uniprotkb:A1IGE6|uniprotkb:A7VJJ2|uniprotkb:A7VJJ3|uniprotkb:A7VJJ4|uniprotkb:A7VJJ5|uniprotkb:B2R9M5|uniprotkb:B4E1G0|uniprotkb:J3KQY9|uniprotkb:Q5CZ85|uniprotkb:Q7Z6N1|ensembl:ENSP00000339168 psi-mi:"(1->3)-beta-d-glucan"(display_short)|psi-mi:"CHEBI:37671"(display_long)|intact:"(1,3-beta-D-glucosyl)n"(synonym)|intact:"(1,3-beta-D-Glucosyl)n"(synonym)|intact:"(1,3-beta-D-Glucosyl)n+1"(synonym)|intact:"(1,3-beta-D-Glucosyl)n-1"(synonym)|intact:1,3-beta-D-Glucan(synonym)|intact:1,3-beta-Glucan(synonym)|intact:"beta-(1,3)-glucan"(synonym)|intact:beta-1,3-glucan(synonym)|intact:callose(synonym)|intact:curdlan(synonym)|intact:zymosan(synonym)|intact:"(1->3)-beta-D-glucopyranan"(iupac name) psi-mi:col11_human(display_long)|uniprotkb:COLEC11(gene name)|psi-mi:COLEC11(display_short)|uniprotkb:Collectin kidney protein 1(gene name synonym)|uniprotkb:UNQ596/PRO1182(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054672|imex:IM-29145-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001242911.1|refseq:NP_001242912.1|refseq:NP_001242913.1|refseq:NP_001242914.1|refseq:NP_001242915.1|refseq:NP_001242916.1|refseq:NP_001242917.1|refseq:NP_001242918.1|refseq:NP_076932.1|refseq:NP_954705.1|interpro:IPR018378|interpro:IPR033990|rcsb pdb:4YLI|rcsb pdb:4YMD|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-3000480|ensembl:ENSG00000118004(gene)|ensembl:ENST00000349077(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0032502"(developmental process)|go:"GO:0042806"(fucose binding)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0120153"(calcium-dependent carbohydrate binding)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold) - - - figure legend:1C, number 3|comment:Positive control|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/04 - rogid:2tl/YlPmHk+6ScRSkMYFZnOCXjg9606 - false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:O00187 uniprotkb:P0DTC9 intact:EBI-7965040|uniprotkb:Q9UMV3|intact:MINT-7970114|uniprotkb:Q9ULC7|uniprotkb:Q9Y270|uniprotkb:A8MWJ2|uniprotkb:O75754|uniprotkb:Q96QG4|uniprotkb:Q9UBP3|uniprotkb:Q5TEQ5|uniprotkb:Q5TER0|uniprotkb:Q9H498|uniprotkb:Q9UC48|uniprotkb:A8K458|uniprotkb:Q9H499|uniprotkb:Q9BZH0|ensembl:ENSP00000383690 intact:EBI-25475856 psi-mi:masp2_human(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MBL-associated serine protease 2(gene name synonym) psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-27054805|imex:IM-29145-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_631947.1|refseq:NP_006601.2|ensembl:ENSG00000009724(gene)|ensembl:ENST00000400897(transcript)|go:"GO:0001855"(complement component C4b binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR037571|interpro:IPR043504|rcsb pdb:1Q3X|rcsb pdb:1SZB|rcsb pdb:1ZJK|rcsb pdb:3TVJ|rcsb pdb:4FXG|rcsb pdb:5JPM|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 - comment:mint - figure legend:4A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/05 rogid:S48IDwjdZ8M6vIJD6iM0XplSN609606 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rigid:YIt6FRo2z2tqjjpUlCJbRaSwKOw false sufficient binding region:298..298-684..684 - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P0C0L4 uniprotkb:P0C0L5 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 intact:EBI-2872887|ensembl:ENSP00000364321|ensembl:ENSP00000407942|ensembl:ENSP00000412786|ensembl:ENSP00000414200|ensembl:ENSP00000415941|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:Q14033|uniprotkb:P01028|uniprotkb:Q13906|uniprotkb:Q13160|uniprotkb:Q14835|uniprotkb:P78445|uniprotkb:A2BHY4|uniprotkb:Q6U2E9|uniprotkb:Q6U2G1|uniprotkb:Q6U2I5|uniprotkb:Q6U2L1|uniprotkb:Q6U2L7|uniprotkb:Q6U2L9|uniprotkb:Q6U2M5|uniprotkb:Q6VCV8|uniprotkb:Q96SA7 psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:co4b_human(display_long)|uniprotkb:C4B(gene name)|psi-mi:C4B(display_short)|uniprotkb:C4B_2(gene name)|psi-mi:C4B_2(display_short)|uniprotkb:Basic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3(gene name synonym)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD3(gene name synonym) psi-mi:"MI:0435"(protease assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-27054873|imex:IM-29145-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 ensembl:ENSG00000224389(gene)|ensembl:ENSG00000228267(gene)|ensembl:ENSG00000228454(gene)|ensembl:ENSG00000233312(gene)|ensembl:ENSG00000236625(gene)|ensembl:ENST00000375177(transcript)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|ensembl:ENST00000411583(transcript)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|ensembl:ENST00000435363(transcript)|go:"GO:0030425"(dendrite)|ensembl:ENST00000435500(transcript)|go:"GO:0032490"(detection of molecule of bacterial origin)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|ensembl:ENST00000449788(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0001848"(complement binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0106139"(symbiont cell surface)|go:"GO:0005576"(extracellular region)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|go:"GO:0005615"(extracellular space)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|go:"GO:0005886"(plasma membrane)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|rcsb pdb:4XAM|rcsb pdb:6YSQ|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-977606|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|mint:P0C0L5|refseq:NP_001002029.3|refseq:NP_001229752.1|dip:DIP-47260N - - - figure legend:4B|comment:Addition of antibody HG4 inhibited MASP-2 mediated C4 cleavage.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/05 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 rogid:Q4ytozbL9pAYkvi+FftBnQ2fJvw9606 rigid:NSxgWDl7yJ0/V+32dhGQQvNuuFM false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P0C0L4 uniprotkb:O00187 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 intact:EBI-7965040|uniprotkb:Q9UMV3|intact:MINT-7970114|uniprotkb:Q9ULC7|uniprotkb:Q9Y270|uniprotkb:A8MWJ2|uniprotkb:O75754|uniprotkb:Q96QG4|uniprotkb:Q9UBP3|uniprotkb:Q5TEQ5|uniprotkb:Q5TER0|uniprotkb:Q9H498|uniprotkb:Q9UC48|uniprotkb:A8K458|uniprotkb:Q9H499|uniprotkb:Q9BZH0|ensembl:ENSP00000383690 psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:masp2_human(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MBL-associated serine protease 2(gene name synonym) psi-mi:"MI:0435"(protease assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-27054873|imex:IM-29145-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 refseq:NP_631947.1|refseq:NP_006601.2|ensembl:ENSG00000009724(gene)|ensembl:ENST00000400897(transcript)|go:"GO:0001855"(complement component C4b binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR037571|interpro:IPR043504|rcsb pdb:1Q3X|rcsb pdb:1SZB|rcsb pdb:1ZJK|rcsb pdb:3TVJ|rcsb pdb:4FXG|rcsb pdb:5JPM|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086 - - comment:mint figure legend:4B|comment:Addition of antibody HG4 inhibited MASP-2 mediated C4 cleavage.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/05 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 rogid:S48IDwjdZ8M6vIJD6iM0XplSN609606 rigid:NSxgWDl7yJ0/V+32dhGQQvNuuFM false - sufficient binding region:298..298-684..684 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P0C0L4 uniprotkb:P0DTC9 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 intact:EBI-25475856 psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Ali et al. (2020) imex:IM-29145|pubmed:34290717 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-27054873|imex:IM-29145-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 - - - figure legend:4B|comment:Addition of antibody HG4 inhibited MASP-2 mediated C4 cleavage.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/27 2021/08/05 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rigid:NSxgWDl7yJ0/V+32dhGQQvNuuFM false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)