#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O95786	uniprotkb:A0A2S1WCF9	intact:EBI-995350|uniprotkb:Q5HYE1|uniprotkb:Q5VYT1|uniprotkb:Q9NT04|uniprotkb:A2RU81|ensembl:ENSP00000369213	intact:EBI-27032942	psi-mi:ddx58_human(display_long)|uniprotkb:DEAD box protein 58(gene name synonym)|uniprotkb:Retinoic acid-inducible gene 1 protein(gene name synonym)|uniprotkb:DDX58(gene name)|psi-mi:DDX58(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX58(gene name synonym)|uniprotkb:Retinoic acid-inducible gene I protein(gene name synonym)|uniprotkb:RIG-I-like receptor 1(gene name synonym)	psi-mi:a0a2s1wcf9_9alpc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2020)	imex:IM-29083|pubmed:34220846	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2018513(Porcine enteric alphacoronavirus)|taxid:2018513(Porcine enteric alphacoronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27032938|imex:IM-29083-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0032587"(ruffle membrane)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000107201(gene)|ensembl:ENST00000379883(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011029(DEATH-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|interpro:IPR042145|mint:O95786|rcsb pdb:2LWD|rcsb pdb:2LWE|rcsb pdb:2QFB|rcsb pdb:2QFD|rcsb pdb:2RMJ|rcsb pdb:2YKG|rcsb pdb:3LRN|rcsb pdb:3LRR|rcsb pdb:3NCU|rcsb pdb:3OG8|rcsb pdb:3ZD6|rcsb pdb:3ZD7|rcsb pdb:4AY2|rcsb pdb:4BPB|rcsb pdb:4NQK|rcsb pdb:4ON9|rcsb pdb:4P4H|rcsb pdb:5E3H|rcsb pdb:5F98|rcsb pdb:5F9F|rcsb pdb:5F9H|rcsb pdb:6GPG|rcsb pdb:6KYV|rcsb pdb:7JL1|rcsb pdb:7JL3|reactome:R-HSA-1169408|reactome:R-HSA-168928|go:"GO:0071360"(cellular response to exogenous dsRNA)|reactome:R-HSA-5689880|reactome:R-HSA-5689896|go:"GO:0051607"(defense response to virus)|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-8983711|refseq:NP_055129.2|dip:DIP-35444N	go:"GO:0003723"(RNA binding)|go:"GO:0019013"(viral nucleocapsid)|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195	-	-	-	figure legend:4|comment:The interaction was not RNA dependent.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/07/13	2021/07/13	rogid:nAw8D8xPo46hNj9gg2hjFeA5Mtc9606	rogid:Ahtjvkv8Xvf/3rU+fK9+JcbR91Q2018513	rigid:d4/9R/2+NmumIGJ4AjfxBNR6jQU	false	flag tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)