#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475874	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27039938|wwpdb:6WIQ|wwpdb:6wqd|wwpdb:6xip|imex:IM-29114-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3860|chain-seq-end:3942	figure legend:Table S1|comment:"Crystals of Nsp7/8A (PDB: 6WIQ) were shown to have a truncated N-terminus (at residue Glu78) for Nsp8. For entries B/C (6WQD and 6XIP) NSP8 also starts   at Asp78 because of the truncation by protease V8/Glu-C."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2021/07/05	2021/07/21	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:9bglx2taGFlx9F8JoF9EfOktY+Y	false	sufficient binding region:78-198	-	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449625	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475871	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040232|imex:IM-29114-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3860|chain-seq-end:3942	chain-seq-start:3860|chain-seq-end:3942	figure legend:3A,2, 4A bottom, 5A bottom, supp. figure 2,  table S2|comment:Nsp7 forms multimers and dimers.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:zjKE+XaqyKFGdecaA//7RKoh5sM	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449625	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475871	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040241|imex:IM-29114-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3860|chain-seq-end:3942	chain-seq-start:3860|chain-seq-end:3942	figure legend:3A,2, Supp. figure 2,  table S2|comment:Nsp7 forms multimers and dimers.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:PuTnm8wll99KXQJqJmLFDCUfbus	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475874	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040246|imex:IM-29114-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3943|chain-seq-end:4140	figure legend:3A,2, table S2|comment:Nsp8 forms concentration-dependent oligomers in solution.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:YfH9+EduizUNu3bJ/GlfZFr5dHY	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475874	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040534|imex:IM-29114-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3943|chain-seq-end:4140	figure legend:3A,2, 4A, table S2|comment:Nsp8 forms concentration-dependent oligomers in solution.|comment:"Figure 3A: In this figure Nsp8 appears to form one peak with an M.Wt of ~110 kDa. (calculated M. Wt of monomer is  ~22kDa)  Figure 4A also shows one peak for Nsp8, but as there are no values given for M.Wt values on the upper part of the X-axis, is it not possible to estimate the M.wt of this peak."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:s5ejA5fuX20Ni7IAubjYH38EFcI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475874	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27041213|imex:IM-29114-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3860|chain-seq-end:3942	figure legend:4A, bottom,Table S2|comment:A transient complex composed of oligomers and free proteins.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:9bglx2taGFlx9F8JoF9EfOktY+Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27041834|imex:IM-29114-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:4A top, 2, Supp. figure 5,Table S2|comment:"Neither Figure 2 or 4 (Supp. figure 5)  indicate which form of ssRNA was used, but the text states:- \"Nsp8 did bind the long ssRNA, but not the short ssRNA, at high affinity. The mixture of Nsp8 with long ssRNA shows only one distinct peak, consistent with the 1:1 complex.\""|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449625	-	intact:EBI-25475871	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27042878|imex:IM-29114-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3860|chain-seq-end:3942	figure legend:4A bottom, 2|comment:These experiments do not support a stable ternary Nsp7/8 dsRNA complex.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27042878|imex:IM-29114-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:4A bottom, 2|comment:These experiments do not support a stable ternary Nsp7/8 dsRNA complex.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	intact:EBI-27041503	-	-	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27042878|imex:IM-29114-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:4A bottom, 2|comment:These experiments do not support a stable ternary Nsp7/8 dsRNA complex.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	-	-	false	sufficient binding region:?-?	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449629	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475885	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043109|imex:IM-29114-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:4393|chain-seq-end:5324	chain-seq-start:3943|chain-seq-end:4140	figure legend:5A top, table S2|comment:There is no Nsp8/12 interaction with RNA.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:kUYuGjSimMr7yS51yZko2wwLNP4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449625	-	intact:EBI-25475871	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043276|imex:IM-29114-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3860|chain-seq-end:3942	figure legend:5A bottom, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043276|imex:IM-29114-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:5A bottom, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	sufficient binding region:?-?	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449629	-	intact:EBI-25475885	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043276|imex:IM-29114-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:4393|chain-seq-end:5324	figure legend:5A bottom, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	intact:EBI-27041503	-	-	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043276|imex:IM-29114-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:5A bottom, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	-	-	false	sufficient binding region:?-?	sufficient binding region:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041503	intact:EBI-27041225	-	-	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043346|imex:IM-29114-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:Supp. figure 3|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449625	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475871	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27044906|imex:IM-29114-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3860|chain-seq-end:3942	chain-seq-start:3943|chain-seq-end:4140	figure legend:5A bottom, 2, Supp. figure 7, Table S2|comment:A heterogeneous and  weak Nsp7/8/12 complex. Nsp7/8/12 does not form a stable structure until RNA is present.  The first SEC trace, shows a split peak and tail with a significant peak from Nsp7 at later elution times, already suggesting transient dissociation of Nsp7 from the Nsp8/12 complex.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/26	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:TdMBDIvOL7GW+tgRvY3boc7Q6tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449625	uniprotkb:P0DTD1-PRO_0000449629	intact:EBI-25475871	intact:EBI-25475885	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27044906|imex:IM-29114-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3860|chain-seq-end:3942	chain-seq-start:4393|chain-seq-end:5324	figure legend:5A bottom, 2, Supp. figure 7, Table S2|comment:A heterogeneous and  weak Nsp7/8/12 complex. Nsp7/8/12 does not form a stable structure until RNA is present.  The first SEC trace, shows a split peak and tail with a significant peak from Nsp7 at later elution times, already suggesting transient dissociation of Nsp7 from the Nsp8/12 complex.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/26	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	rigid:TdMBDIvOL7GW+tgRvY3boc7Q6tU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475874	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040225|imex:IM-29114-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3860|chain-seq-end:3942	figure legend:4B,2, table S2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:9bglx2taGFlx9F8JoF9EfOktY+Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449625	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475871	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040354|imex:IM-29114-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3860|chain-seq-end:3942	chain-seq-start:3860|chain-seq-end:3942	figure legend:3B,2, Supp. figure 2B, table S2|comment:Best-fit model for Nsp7 is an alternate dimer.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:zjKE+XaqyKFGdecaA//7RKoh5sM	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475874	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040412|imex:IM-29114-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3943|chain-seq-end:4140	figure legend:3B,2, Supp. figure 4, table S2|comment:A mixture of the dimer and monomer models fitted the SAXS data for Nsp8 at a 2.5 mg/mL concentration  and the SAXS data from the leading edge of the SEC major elution peak.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:YfH9+EduizUNu3bJ/GlfZFr5dHY	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27041221|imex:IM-29114-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:4 B/C, 2, Table S2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	intact:EBI-27041503	-	-	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27041221|imex:IM-29114-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:4 B/C, 2, Table S2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	-	-	-	false	sufficient binding region:?-?	sufficient binding region:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449625	-	intact:EBI-25475871	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043289|imex:IM-29114-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3860|chain-seq-end:3942	figure legend:5B, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043289|imex:IM-29114-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:5B, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	sufficient binding region:?-?	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449629	-	intact:EBI-25475885	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043289|imex:IM-29114-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:4393|chain-seq-end:5324	figure legend:5B, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	-	false	sufficient binding region:?-?	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	intact:EBI-27041503	-	-	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043289|imex:IM-29114-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:5B, 2, Table S2|comment:"The addition of dsRNA or ssRNA stabilizes the Nsp7/8/12/RNA within a 1:2:1:1 complex;unfortunately the identity of the ssRNA is not stated."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	-	-	false	sufficient binding region:?-?	sufficient binding region:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449629	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475885	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043301|imex:IM-29114-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:4393|chain-seq-end:5324	chain-seq-start:3943|chain-seq-end:4140	figure legend:5B, table S2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:kUYuGjSimMr7yS51yZko2wwLNP4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041225	intact:EBI-27041503	-	-	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:"MI:0826"(x ray scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043357|imex:IM-29114-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	-	-	-	figure legend:Supp. figure 3, figure 2.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449625	intact:EBI-25475874	intact:EBI-25475871	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0888"(small angle neutron scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27040452|imex:IM-29114-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3860|chain-seq-end:3942	figure legend:2, 3F, 4G, Table S2|comment:Nsp7 dramatically modifies Nsp8 conformation or assembly.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/22	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	rigid:9bglx2taGFlx9F8JoF9EfOktY+Y	false	-	2h label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTD1-PRO_0000449626	uniprotkb:P0DTD1-PRO_0000449626	intact:EBI-25475874	intact:EBI-25475874	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0888"(small angle neutron scattering)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043058|imex:IM-29114-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:3943|chain-seq-end:4140	chain-seq-start:3943|chain-seq-end:4140	figure legend:2,  Table S2|comment:"M. Wt for Nsp8 is given as 38 kDa for SANS in table S2. (Monomer =24kDa)"|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	rigid:YfH9+EduizUNu3bJ/GlfZFr5dHY	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27041503	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:short_ssrna oligo(display_short)|psi-mi:EBI-27041503(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27042894|imex:IM-29114-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:4D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	radiolabel:?-?	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-27041225	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:long_ssrna oligo(display_short)|psi-mi:EBI-27041225(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27042905|imex:IM-29114-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	-	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	-	chain-seq-start:3943|chain-seq-end:4140	figure legend:4D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	radiolabel:?-?|sufficient binding region:5-36	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-27043337	uniprotkb:P0DTD1-PRO_0000449625	-	intact:EBI-25475871	psi-mi:31mer_hairpin_rna(display_short)|psi-mi:EBI-27043337(display_long)	psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0700"(rna directed rna polymerase assay)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043318|imex:IM-29114-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank identifier:MW365029(see-also)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	comment:"residues 9-23 map to MW365029.1 (SARS-CoV-2/human/CHL/Santiago-PUC_MVL_0400/2020)"	chain-seq-start:3860|chain-seq-end:3942	figure legend:Supp. figure 1|antagonist:"EDTA;CHEBI:42191"|comment:The RTC creating duplexed 36 basepaired RNA from a 31 base hairpin substrate.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049	-	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-27043337	uniprotkb:P0DTD1-PRO_0000449626	-	intact:EBI-25475874	psi-mi:31mer_hairpin_rna(display_short)|psi-mi:EBI-27043337(display_long)	psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0700"(rna directed rna polymerase assay)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043318|imex:IM-29114-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank identifier:MW365029(see-also)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	comment:"residues 9-23 map to MW365029.1 (SARS-CoV-2/human/CHL/Santiago-PUC_MVL_0400/2020)"	chain-seq-start:3943|chain-seq-end:4140	figure legend:Supp. figure 1|antagonist:"EDTA;CHEBI:42191"|comment:The RTC creating duplexed 36 basepaired RNA from a 31 base hairpin substrate.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049	-	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-27043337	uniprotkb:P0DTD1-PRO_0000449629	-	intact:EBI-25475885	psi-mi:31mer_hairpin_rna(display_short)|psi-mi:EBI-27043337(display_long)	psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0700"(rna directed rna polymerase assay)	Wilamowski et al. (2021)	pubmed:34197805|imex:IM-29114	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27043318|imex:IM-29114-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	genbank identifier:MW365029(see-also)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	comment:"residues 9-23 map to MW365029.1 (SARS-CoV-2/human/CHL/Santiago-PUC_MVL_0400/2020)"	chain-seq-start:4393|chain-seq-end:5324	figure legend:Supp. figure 1|antagonist:"EDTA;CHEBI:42191"|comment:The RTC creating duplexed 36 basepaired RNA from a 31 base hairpin substrate.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/07/05	2021/07/23	-	rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049	-	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)