#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0A087WPF7 uniprotkb:Q99K48 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-607499|ensembl:ENSMUSP00000033673|uniprotkb:Q63887|uniprotkb:Q9CYQ4|uniprotkb:Q9DBP2 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:nono_mouse(display_long)|uniprotkb:Nono(gene name)|psi-mi:Nono(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000031311(gene)|ensembl:ENSMUST00000033673(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q99K48|rcsb pdb:2CPJ|rcsb pdb:2RS8|refseq:NP_075633.2|refseq:NP_001239447.1|dip:DIP-34308N go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:78ly3/4yzdfLjl9d/cV6Ob/SFG810090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P62996 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-8320461|uniprotkb:O15449|uniprotkb:Q64283|intact:MINT-4138402|uniprotkb:Q15815|ensembl:ENSMUSP00000124846 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:tra2b_mouse(display_long)|uniprotkb:Silg41(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym)|uniprotkb:Silica-induced gene 41 protein(gene name synonym)|uniprotkb:Tra2b(gene name)|psi-mi:Tra2b(display_short)|uniprotkb:Sfrs10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_033212.1|refseq:NP_001317483.1|refseq:NP_001317484.1|ensembl:ENSMUSG00000022858(gene)|ensembl:ENSMUST00000161286(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62996|reactome:R-MMU-72163|reactome:R-MMU-9013418|reactome:R-MMU-9013422 go:"GO:0005634"(nucleus) - comment:mint|function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q9CXS4 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-8340199|intact:MINT-4125766|uniprotkb:B2RWK8|uniprotkb:B9EK22|uniprotkb:Q5SX21|intact:MINT-8174236|uniprotkb:Q6PIA5|ensembl:ENSMUSP00000018653 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:cenpv_mouse(display_long)|uniprotkb:Cenpv(gene name)|psi-mi:Cenpv(display_short)|uniprotkb:Prr6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_082724.1|ensembl:ENSMUSG00000018509(gene)|ensembl:ENSMUST00000018653(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q9CXS4 go:"GO:0005634"(nucleus) - comment:mint comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:7JgDE/uuCpLcOUBwevDaG4ljXow10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q64511 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-2325586|uniprotkb:Q7TQG4|ensembl:ENSMUSP00000017629 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:top2b_mouse(display_long)|uniprotkb:Top2b(gene name)|psi-mi:Top2b(display_short)|uniprotkb:DNA topoisomerase II, beta isozyme(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_033435.2|ensembl:ENSMUSG00000017485(gene)|ensembl:ENSMUST00000017629(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0007409"(axonogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030900"(forebrain development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071318"(cellular response to ATP)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR028467|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:Q64511|reactome:R-MMU-4615885 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:dB5M5wdu6YqBC7uBMe34toA5ISQ10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P43274 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-913424|ensembl:ENSMUSP00000057308|uniprotkb:Q5EBH3 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h14_mouse(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1 VAR.2(gene name synonym)|uniprotkb:H1e(gene name synonym)|uniprotkb:H1f4(gene name synonym)|uniprotkb:Hist1h1e(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000051627(gene)|ensembl:ENSMUST00000062045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43274|reactome:R-MMU-140342|reactome:R-MMU-2559584|refseq:NP_056602.1 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:RbnBt0O11C8PWtfWp8tJJxsn00A10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q61656 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q501J6 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q8BL97 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-913123|uniprotkb:Q8BMC6|uniprotkb:Q8BUR2|uniprotkb:Q8R2N4|uniprotkb:Q8R3E9|uniprotkb:Q91YS1 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:srsf7_mouse(display_long)|uniprotkb:Srsf7(gene name)|psi-mi:Srsf7(display_short)|uniprotkb:Sfrs7(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|reactome:R-MMU-73856|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034651|interpro:IPR035979|interpro:IPR036875|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72187|refseq:NP_001182414.1|refseq:NP_001182415.1|refseq:NP_001182416.1|refseq:NP_666195.1|refseq:XP_006524253.1|mint:Q8BL97|dip:DIP-36580N go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:dgBF3NFB/dJM+SEsycw66i4Z86g10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q61686 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-307973|uniprotkb:Q9CS35|uniprotkb:Q9CXD1|ensembl:ENSMUSP00000104441|ensembl:ENSMUSP00000113157|ensembl:ENSMUSP00000113158 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:cbx5_mouse(display_long)|uniprotkb:Cbx5(gene name)|psi-mi:Cbx5(display_short)|uniprotkb:Hp1a(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000009575(gene)|ensembl:ENSMUST00000108813(transcript)|ensembl:ENSMUST00000118152(transcript)|ensembl:ENSMUST00000122182(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:Q61686|rcsb pdb:2RVL|rcsb pdb:2RVM|rcsb pdb:2RVN|reactome:R-MMU-983231|refseq:NP_001070257.1|refseq:NP_001103686.1|refseq:NP_031652.1|refseq:XP_006520435.1|refseq:XP_006520437.1|refseq:XP_006520438.1|refseq:XP_006520439.1|dip:DIP-28137N go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:B81xFbqA5shBoYVh//QAPgY/iLI10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P56959 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-400452|ensembl:ENSMUSP00000101858 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:fus_mouse(display_long)|uniprotkb:Fus(gene name)|psi-mi:Fus(display_short)|uniprotkb:Protein pigpen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_631888.1|ensembl:ENSMUSG00000030795(gene)|ensembl:ENSMUST00000106251(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P56959|reactome:R-MMU-72163 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:Vwv/0vlM50l49XaUOHCtEWt/b2A10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P23198 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-78162|uniprotkb:Q921C4 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:cbx3_mouse(display_long)|uniprotkb:Cbx3(gene name)|psi-mi:Cbx3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:M32(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|reactome:R-MMU-73772|reactome:R-MMU-8953750|dip:DIP-28136N|mint:P23198 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:mD/Ut3JqLl3k0Ut98GxlstErEGs10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P43277 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-299625|ensembl:ENSMUSP00000044395|uniprotkb:Q8C6M4 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h13_mouse(display_long)|uniprotkb:H1-3(gene name)|psi-mi:H1-3(display_short)|uniprotkb:H1 VAR.4(gene name synonym)|uniprotkb:H1d(gene name synonym)|uniprotkb:H1f3(gene name synonym)|uniprotkb:Hist1h1d(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000052565(gene)|ensembl:ENSMUST00000045301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43277|reactome:R-MMU-140342|go:"GO:0000786"(nucleosome)|reactome:R-MMU-2559584|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|refseq:NP_663759.3 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:az/dCjeaJAf5G/5QRQeFE9Q63Ps10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P43276 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-903960|uniprotkb:Q9CRM8|ensembl:ENSMUSP00000079356 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h15_mouse(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1 VAR.5(gene name synonym)|uniprotkb:H1b(gene name synonym)|uniprotkb:H1f5(gene name synonym)|uniprotkb:Hist1h1b(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_064418.1|ensembl:ENSMUSG00000058773(gene)|ensembl:ENSMUST00000080511(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43276|reactome:R-MMU-140342|reactome:R-MMU-2559584 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:XG7QIbZHXPP+4PO4OY4XdcBAZlc10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P84104 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-2550426|ensembl:ENSMUSP00000117045|uniprotkb:O08831|uniprotkb:P23152|uniprotkb:Q564E9 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:srsf3_mouse(display_long)|uniprotkb:Sfrs3(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 3(gene name synonym)|uniprotkb:Srsf3(gene name)|psi-mi:Srsf3(display_short)|uniprotkb:Srp20(gene name synonym)|uniprotkb:X16(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP20(gene name synonym)|uniprotkb:Protein X16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000071172(gene)|ensembl:ENSMUST00000130216(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P84104|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|refseq:NP_038691.1 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:BcfyCj2cNNTH1igANKpvh4IHDVU10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q9QZQ8 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-3508334|uniprotkb:Q91VZ2|uniprotkb:Q9QZQ7|ensembl:ENSMUSP00000016081 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h2ay_mouse(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)|uniprotkb:H2afy(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_001152985.1|refseq:NP_001152986.1|refseq:NP_001152987.1|refseq:NP_036145.1|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:0005730"(nucleolus)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|go:"GO:0005813"(centrosome)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|interpro:IPR032454|go:"GO:0007549"(dosage compensation)|interpro:IPR035796|interpro:IPR043472|mint:Q9QZQ8|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|ensembl:ENSMUSG00000015937(gene)|ensembl:ENSMUST00000016081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding) go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:70q7YQGYxyE7ZBq8e7oOsIUSY0810090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q8CCK0 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-20313485|uniprotkb:A0JP36|uniprotkb:Q3TNT4|uniprotkb:Q925I6|ensembl:ENSMUSP00000020283 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h2aw_mouse(display_long)|uniprotkb:Macroh2a2(gene name)|psi-mi:Macroh2a2(display_short)|uniprotkb:H2afy2(gene name synonym)|uniprotkb:H2afy3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_996883.1|ensembl:ENSMUSG00000020086(gene)|ensembl:ENSMUST00000020283(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007420"(brain development)|go:"GO:0007549"(dosage compensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:Q8CCK0 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:VDYaQkuXNy0GqZ4NPpvUOToqdq410090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:Q8VIJ6 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-6094576|uniprotkb:A2A7U6|uniprotkb:Q9ERW2|ensembl:ENSMUSP00000030623 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:sfpq_mouse(display_long)|uniprotkb:Sfpq(gene name)|psi-mi:Sfpq(display_short)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:Psf(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_076092.1|ensembl:ENSMUSG00000028820(gene)|ensembl:ENSMUST00000030623(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:Q8VIJ6|reactome:R-MMU-8849468 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:9mciNgfKrEvyAv7kjs55FHlUtRY10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P68369 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-400542|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q3TGF0|uniprotkb:Q3TIW2|uniprotkb:Q3TPJ1|uniprotkb:Q3ULN1|uniprotkb:Q5XJF8|ensembl:ENSMUSP00000094778 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:tba1a_mouse(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-1(gene name synonym)|uniprotkb:Tuba1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 refseq:NP_035783.1|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|ensembl:ENSMUSG00000072235(gene)|ensembl:ENSMUST00000097014(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68369|rcsb pdb:6JZD|reactome:R-MMU-190840|reactome:R-MMU-2132295 go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A087WPF7 uniprotkb:P62806 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006 psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27122359|imex:IM-29338-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N go:"GO:0005634"(nucleus) - - comment:AUTS2 was immunoprecipitated from pooled P0.5 cortices.|figure legend:F2A|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090 rigid:qTKL4C3E0MtqUNwX8iTPs6x/X3s false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99K48 uniprotkb:A0A087WPF7 intact:EBI-607499|ensembl:ENSMUSP00000033673|uniprotkb:Q63887|uniprotkb:Q9CYQ4|uniprotkb:Q9DBP2 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 psi-mi:nono_mouse(display_long)|uniprotkb:Nono(gene name)|psi-mi:Nono(display_short) psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27122434|imex:IM-29338-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031311(gene)|ensembl:ENSMUST00000033673(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q99K48|rcsb pdb:2CPJ|rcsb pdb:2RS8|refseq:NP_075633.2|refseq:NP_001239447.1|dip:DIP-34308N refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:F2D|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:78ly3/4yzdfLjl9d/cV6Ob/SFG810090 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rigid:uAfXhJenfZ19EgagZEBKkOO7krA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99K48 uniprotkb:A0A087WPF7 intact:EBI-607499|ensembl:ENSMUSP00000033673|uniprotkb:Q63887|uniprotkb:Q9CYQ4|uniprotkb:Q9DBP2 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 psi-mi:nono_mouse(display_long)|uniprotkb:Nono(gene name)|psi-mi:Nono(display_short) psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27122438|imex:IM-29338-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031311(gene)|ensembl:ENSMUST00000033673(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q99K48|rcsb pdb:2CPJ|rcsb pdb:2RS8|refseq:NP_075633.2|refseq:NP_001239447.1|dip:DIP-34308N refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:F2E|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/12/27 rogid:78ly3/4yzdfLjl9d/cV6Ob/SFG810090 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rigid:uAfXhJenfZ19EgagZEBKkOO7krA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99K48 uniprotkb:A0A087WPF7 intact:EBI-607499|ensembl:ENSMUSP00000033673|uniprotkb:Q63887|uniprotkb:Q9CYQ4|uniprotkb:Q9DBP2 intact:EBI-27122375|uniprotkb:E9PWJ4|uniprotkb:Q6ZQB3|uniprotkb:Q8BWI6|ensembl:ENSMUSP00000159434 psi-mi:nono_mouse(display_long)|uniprotkb:Nono(gene name)|psi-mi:Nono(display_short) psi-mi:auts2_mouse(display_long)|uniprotkb:Auts2(gene name)|psi-mi:Auts2(display_short)|uniprotkb:Kiaa0442(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Castanza et al. (2021) imex:IM-29338|pubmed:34013328 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27122451|imex:IM-29338-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031311(gene)|ensembl:ENSMUST00000033673(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q99K48|rcsb pdb:2CPJ|rcsb pdb:2RS8|refseq:NP_075633.2|refseq:NP_001239447.1|dip:DIP-34308N refseq:NP_796021.2|ensembl:ENSMUSG00000029673(gene)|ensembl:ENSMUST00000161226(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060013"(righting reflex)|go:"GO:0097484"(dendrite extension)|go:"GO:0098582"(innate vocalization behavior)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-MMU-8939243 go:"GO:0005634"(nucleus) - - figure legend:F2B, F2C|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/11/09 2021/11/09 rogid:78ly3/4yzdfLjl9d/cV6Ob/SFG810090 rogid:DoRMPDrkZTUrq15qfbGNDXvwA/o10090 rigid:uAfXhJenfZ19EgagZEBKkOO7krA false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)