#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0DTD1-PRO_0000449631	uniprotkb:P0DTD1-PRO_0000449628	intact:EBI-25475920	intact:EBI-25475880	psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974926|wwpdb:7DIY|imex:IM-28946-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:5926|chain-seq-end:6452	chain-seq-start:4254|chain-seq-end:4392	figure legend:Supplementary Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2021/05/07	2021/05/24	rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049	rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049	rigid:31XhqL6F4tfEjhLqU/s/PXVionw	false	sufficient binding region:1-289	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:6636"	intact:EBI-26975088	intact:EBI-26975104	-	psi-mi:magnesium dichloride(display_short)|psi-mi:"CHEBI:6636"(display_long)|intact:[MgCl2](synonym)|intact:Magnesium chloride(synonym)|intact:Magnesium chloride anhydrous(synonym)|intact:Magnesiumchlorid(synonym)|intact:MgCl2(synonym)|intact:magnesium dichloride(iupac name)	psi-mi:34-nt  rna substrate(display_short)|psi-mi:EBI-26975088(display_long)	psi-mi:"MI:0920"(ribonuclease assay)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975081|imex:IM-28946-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	go:"GO:0004532"(exoribonuclease activity)	-	-	figure legend:5 C-F, 6|antagonist:"EDTA:CHEBI:42191"|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/05/07	2022/01/04	-	-	-	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-26975088	intenz:3.1.13	-	intact:EBI-25564924|intact:EBI-25492032|reactome:R-COV-9694688|wwpdb:7diy|wwpdb:7mc6|wwpdb:7mc5|wwpdb:7n0c|emdb:EMD-24103|wwpdb:7n0d|emdb:EMD-24104|wwpdb:7n0b|emdb:EMD-24102	psi-mi:34-nt  rna substrate(display_short)|psi-mi:EBI-26975088(display_long)	psi-mi:nsp10-nsp14_sars2-1(display_short)|psi-mi:3.1.13(display_long)|intact:SARS-CoV-2 3'-5' exoribonuclease proof-reading complex(complex recommended name)|intact:"NSP10:NSP14"(complex systematic name)|intact:SARS-CoV-2 NSP14/NSP10 complex(complex synonym)	psi-mi:"MI:0920"(ribonuclease assay)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975081|imex:IM-28946-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:1302"(stable complex)	-	go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:1905354"(exoribonuclease complex)|pubmed:31440227(see-also)|pubmed:29279395(see-also)|efo:"EFO:0000694"(see-also)|pubmed:32015508(see-also)|pubmed:31987001(see-also)|complex portal:CPX-5692(complex-primary)|evidence ontology:"ECO:0000353"|pubmed:33821277(see-also)|intact:EBI-26971334(exp-evidence)	go:"GO:0004532"(exoribonuclease activity)	-	curated-complex:"The SARS-CoV-2 coronavirus 3'-5' exoribonuclease complex which strictly targets double-stranded RNA and can selectively remove a mismatched ribonucleotide at the 3'-end of a dsRNA substrate. Formation of the NSP10-NSP14 complex strongly enhances the exonuclease activity of the bifunctional NSP14 and enhances the fidelity of RNA synthesis by correcting nucleotide incorporation errors made by the RNA-dependent RNA polymerase. May bind to, and act with the nsp7/nsp8/nsp12 polymerase complex (CPX-5742). Proof-reading exonuclease activity may explain why coronaviruses have the largest RNA genomes known to date. Complex formation does not appear to effect the C-terminal N7-methyltransferase activity of NSP14 involved in RNA cap modification."|disease:"Severe acute respiratory syndrome (SARS) [EFO:0000694]: A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death."|complex-properties:NSP10 forms a homododecamer in isolation. A flexible N-terminal domain of NSP14 forms the NSP10 docking site and induces conformational changes in the NSP14 that modulate the distance between the catalytic residues.	figure legend:5 C-F, 6|antagonist:"EDTA:CHEBI:42191"|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/05/07	2022/01/04	-	-	-	false	-	mutation disrupting interaction rate:191-191,268-268,273-273|sufficient binding region:1-289	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
chebi:"CHEBI:63041"	intact:EBI-26975088	intact:EBI-26975129	-	psi-mi:"manganese(ii) chloride"(display_short)|psi-mi:"CHEBI:63041"(display_long)|intact:Manganous chloride(synonym)|intact:manganous dichloride(synonym)|intact:"manganese(2+) dichloride"(iupac name)|intact:dichlorure de manganese(synonym)|intact:Mangandichlorid(synonym)|intact:Manganese bichloride(synonym)|intact:"Manganese(II) chloride (1:2)"(synonym)|intact:"manganese(II) dichloride"(synonym)|intact:manganous chloride(synonym)	psi-mi:34-nt  rna substrate(display_short)|psi-mi:EBI-26975088(display_long)	psi-mi:"MI:0920"(ribonuclease assay)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975116|imex:IM-28946-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0320"(ribonucleic acid)	-	-	go:"GO:0004532"(exoribonuclease activity)	-	-	figure legend:5 C-F, 6|antagonist:"EDTA:CHEBI:42191"|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/05/07	2022/01/04	-	-	-	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-26975088	intenz:3.1.13	-	intact:EBI-25564924|intact:EBI-25492032|reactome:R-COV-9694688|wwpdb:7diy|wwpdb:7mc6|wwpdb:7mc5|wwpdb:7n0c|emdb:EMD-24103|wwpdb:7n0d|emdb:EMD-24104|wwpdb:7n0b|emdb:EMD-24102	psi-mi:34-nt  rna substrate(display_short)|psi-mi:EBI-26975088(display_long)	psi-mi:nsp10-nsp14_sars2-1(display_short)|psi-mi:3.1.13(display_long)|intact:SARS-CoV-2 3'-5' exoribonuclease proof-reading complex(complex recommended name)|intact:"NSP10:NSP14"(complex systematic name)|intact:SARS-CoV-2 NSP14/NSP10 complex(complex synonym)	psi-mi:"MI:0920"(ribonuclease assay)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975116|imex:IM-28946-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:1302"(stable complex)	-	go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:1905354"(exoribonuclease complex)|pubmed:31440227(see-also)|pubmed:29279395(see-also)|efo:"EFO:0000694"(see-also)|pubmed:32015508(see-also)|pubmed:31987001(see-also)|complex portal:CPX-5692(complex-primary)|evidence ontology:"ECO:0000353"|pubmed:33821277(see-also)|intact:EBI-26971334(exp-evidence)	go:"GO:0004532"(exoribonuclease activity)	-	curated-complex:"The SARS-CoV-2 coronavirus 3'-5' exoribonuclease complex which strictly targets double-stranded RNA and can selectively remove a mismatched ribonucleotide at the 3'-end of a dsRNA substrate. Formation of the NSP10-NSP14 complex strongly enhances the exonuclease activity of the bifunctional NSP14 and enhances the fidelity of RNA synthesis by correcting nucleotide incorporation errors made by the RNA-dependent RNA polymerase. May bind to, and act with the nsp7/nsp8/nsp12 polymerase complex (CPX-5742). Proof-reading exonuclease activity may explain why coronaviruses have the largest RNA genomes known to date. Complex formation does not appear to effect the C-terminal N7-methyltransferase activity of NSP14 involved in RNA cap modification."|disease:"Severe acute respiratory syndrome (SARS) [EFO:0000694]: A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death."|complex-properties:NSP10 forms a homododecamer in isolation. A flexible N-terminal domain of NSP14 forms the NSP10 docking site and induces conformational changes in the NSP14 that modulate the distance between the catalytic residues.	figure legend:5 C-F, 6|antagonist:"EDTA:CHEBI:42191"|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/05/07	2022/01/04	-	-	-	false	-	mutation disrupting interaction rate:191-191,268-268,273-273|sufficient binding region:1-289	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P0DTD1-PRO_0000449628	uniprotkb:P0DTD1-PRO_0000449631	intact:EBI-25475880	intact:EBI-25475920	psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0071"(molecular sieving)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975205|imex:IM-28946-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:4254|chain-seq-end:4392	chain-seq-start:5926|chain-seq-end:6452	figure legend:Supp. figure 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2021/05/07	2021/05/14	rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049	rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049	rigid:31XhqL6F4tfEjhLqU/s/PXVionw	false	-	sufficient binding region:1-289|mutation:191-191,268-268,273-273	1	1	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-26975088	intenz:3.1.13	-	intact:EBI-25564924|intact:EBI-25492032|reactome:R-COV-9694688|wwpdb:7diy|wwpdb:7mc6|wwpdb:7mc5|wwpdb:7n0c|emdb:EMD-24103|wwpdb:7n0d|emdb:EMD-24104|wwpdb:7n0b|emdb:EMD-24102	psi-mi:34-nt  rna substrate(display_short)|psi-mi:EBI-26975088(display_long)	psi-mi:nsp10-nsp14_sars2-1(display_short)|psi-mi:3.1.13(display_long)|intact:SARS-CoV-2 3'-5' exoribonuclease proof-reading complex(complex recommended name)|intact:"NSP10:NSP14"(complex systematic name)|intact:SARS-CoV-2 NSP14/NSP10 complex(complex synonym)	psi-mi:"MI:0920"(ribonuclease assay)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0902"(rna cleavage)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975240|imex:IM-28946-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:1302"(stable complex)	-	go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:1905354"(exoribonuclease complex)|pubmed:31440227(see-also)|pubmed:29279395(see-also)|efo:"EFO:0000694"(see-also)|pubmed:32015508(see-also)|pubmed:31987001(see-also)|complex portal:CPX-5692(complex-primary)|evidence ontology:"ECO:0000353"|pubmed:33821277(see-also)|intact:EBI-26971334(exp-evidence)	go:"GO:0004532"(exoribonuclease activity)	-	curated-complex:"The SARS-CoV-2 coronavirus 3'-5' exoribonuclease complex which strictly targets double-stranded RNA and can selectively remove a mismatched ribonucleotide at the 3'-end of a dsRNA substrate. Formation of the NSP10-NSP14 complex strongly enhances the exonuclease activity of the bifunctional NSP14 and enhances the fidelity of RNA synthesis by correcting nucleotide incorporation errors made by the RNA-dependent RNA polymerase. May bind to, and act with the nsp7/nsp8/nsp12 polymerase complex (CPX-5742). Proof-reading exonuclease activity may explain why coronaviruses have the largest RNA genomes known to date. Complex formation does not appear to effect the C-terminal N7-methyltransferase activity of NSP14 involved in RNA cap modification."|disease:"Severe acute respiratory syndrome (SARS) [EFO:0000694]: A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death."|complex-properties:NSP10 forms a homododecamer in isolation. A flexible N-terminal domain of NSP14 forms the NSP10 docking site and induces conformational changes in the NSP14 that modulate the distance between the catalytic residues.	figure legend:Supp. figure 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/05/07	2022/01/04	-	-	-	false	fluorescein label:1-1	sufficient binding region:1-289|mutation disrupting interaction rate:268-268,273-273,191-191	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0DTD1-PRO_0000449631	uniprotkb:P0DTD1-PRO_0000449628	intact:EBI-25475920	intact:EBI-25475880	psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975283|imex:IM-28946-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:5926|chain-seq-end:6452	chain-seq-start:4254|chain-seq-end:4392	figure legend:Supp. figure 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2021/05/07	2021/05/14	rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049	rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049	rigid:31XhqL6F4tfEjhLqU/s/PXVionw	false	sufficient binding region:1-289|maltose binding protein tag:n-n	necessary binding region:22-139|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P0DTD1-PRO_0000449633	uniprotkb:P0DTD1-PRO_0000449628	intact:EBI-25492395	intact:EBI-25475880	psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0096"(pull down)	Lin et al. (2021)	imex:IM-28946|pubmed:33956156	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26975300|imex:IM-28946-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent)	-	chain-seq-start:6799|chain-seq-end:7096	chain-seq-start:4254|chain-seq-end:4392	figure legend:Supp. figure 5|comment:No information is given regarding  Nsp16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2021/05/07	2021/05/14	rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049	rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049	rigid:582Rw1bwfnjhQ9Cimb1tneXw8JA	false	-	sufficient binding region:22-139|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)