#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07157	uniprotkb:P0DTC4	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	intact:EBI-25475850	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972736|imex:IM-28944-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.6x10^-6(molar)	2021/05/11	2021/05/11	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:pIMkuiCWvd5IQ4m49rsXlmsLJPw	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:184-264	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14745	uniprotkb:P0DTC4	intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389	intact:EBI-25475850	psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972816|imex:IM-28944-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:18.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:03E30U6coFBcC3BeKOYnInfG/BI9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:lAT32SjnkxBmkKHe1AeU+J59StY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:146-237	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12923	uniprotkb:P0DTC4	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249	intact:EBI-25475850	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972832|imex:IM-28944-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:24.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:z7jjaUjW9axxKKtUz172S1DoslY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1779-1873	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92743	uniprotkb:P0DTC4	intact:EBI-352256|uniprotkb:Q9UNS5|uniprotkb:D3DRE4|ensembl:ENSP00000357980	intact:EBI-25475850	psi-mi:htra1_human(display_long)|uniprotkb:HTRA1(gene name)|psi-mi:HTRA1(display_short)|uniprotkb:HTRA(gene name synonym)|uniprotkb:PRSS11(gene name synonym)|uniprotkb:High-temperature requirement A serine peptidase 1(gene name synonym)|uniprotkb:L56(gene name synonym)|uniprotkb:Serine protease 11(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972858|imex:IM-28944-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002766.1|ensembl:ENSG00000166033(gene)|ensembl:ENST00000368984(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097187"(dentinogenesis)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|rcsb pdb:2JOA|rcsb pdb:2YTW|rcsb pdb:3NUM|rcsb pdb:3NWU|rcsb pdb:3NZI|rcsb pdb:3TJN|rcsb pdb:3TJO|rcsb pdb:3TJQ|rcsb pdb:6Z0E|rcsb pdb:6Z0X|rcsb pdb:6Z0Y|reactome:R-HSA-1474228|dip:DIP-33195N	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:41.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:Y7lT7nyI9N/3imHOz8Ng+Zagf509606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:+V+rjv9XM8J/Jy7jDDhI8O6JUaw	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:365-480	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N448	uniprotkb:P0DTC4	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	intact:EBI-25475850	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972927|imex:IM-28944-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:61.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:3buZRWaTPoQP4WaixR1Wi1okauE	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:334-426	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TEW0	uniprotkb:P0DTC4	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	intact:EBI-25475850	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972942|imex:IM-28944-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:63.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:/3ZNbIHW5YVhRfaQXrDlO7sLzrU	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:582-685	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96L92	uniprotkb:P0DTC4	intact:EBI-2514865|ensembl:ENSP00000400333|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1	intact:EBI-25475850	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972957|imex:IM-28944-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143376(gene)|ensembl:ENST00000458013(transcript)|go:"GO:0001770"(establishment of natural killer cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|refseq:NP_001317652.1|refseq:NP_112180.4|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR000159(Ras-association)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|interpro:IPR001478(PDZ/DHR/GLGF)	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number  8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:67.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:yj6DThvFPDy3wRiFkPF0U93BaxA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:40-141	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTC4	uniprotkb:Q96JH8	intact:EBI-25475850	intact:EBI-744267|intact:EBI-1058572|uniprotkb:Q0VFZ9|uniprotkb:Q75LH3|uniprotkb:Q9BSP5|uniprotkb:Q9H0M6|uniprotkb:Q9NW43|uniprotkb:Q9NWC4|uniprotkb:B7ZL20|uniprotkb:A4D1Z5|uniprotkb:A5YM49|ensembl:ENSP00000382492	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:radil_human(display_long)|uniprotkb:KIAA1849(gene name synonym)|uniprotkb:RADIL(gene name)|psi-mi:RADIL(display_short)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972971|imex:IM-28944-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	refseq:NP_060529.4|go:"GO:0051020"(GTPase binding)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037983|rcsb pdb:1UM1|rcsb pdb:3EC8|ensembl:ENSG00000157927(gene)|ensembl:ENST00000399583(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number  9|comment:RADIL   found to be KIAA1849.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:75.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rogid:GwG8Ipdgc65+IwI8Bvq00yChi7U9606	rigid:vX/ErowrVrMKi/J1dgK6bUkPrxQ	false	biotin tag:n-n|sufficient binding region:64-75	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:973-1075	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTC4	uniprotkb:P55196	intact:EBI-25475850	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26972987|imex:IM-28944-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion)	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number  10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:82.0x10^-6(molar)	2021/05/11	2021/05/11	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	rigid:CHA9vG7e18/7h0Mt1WnXsY26Wkw	false	biotin tag:n-n|sufficient binding region:64-75	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1002-1097	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P0Q8	uniprotkb:P0DTC4	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	intact:EBI-25475850	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973207|imex:IM-28944-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)	rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1. Number 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:41.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049	rigid:SWjxCg52ECEYwlpd+Z/SfNLp5aI	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1102-1193	biotin tag:n-n|sufficient binding region:64-75	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07157	uniprotkb:P59637	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973086|imex:IM-28944-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:qFqJbrFlJmycL37pCFYXkAYwaic	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:184-264	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P59637	uniprotkb:P55196	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973055|imex:IM-28944-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion)	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:51.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606	rigid:wcvp4Z7cM2fDfvtkR6KIiE9epJk	false	biotin tag:n-n|sufficient binding region:65-76	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1002-1097	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12923	uniprotkb:P59637	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973101|imex:IM-28944-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table  1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:24.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:TEwFl0USQ01j+cFAFwQ4k+nSbOY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1779-1873	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92743	uniprotkb:P59637	intact:EBI-352256|uniprotkb:Q9UNS5|uniprotkb:D3DRE4|ensembl:ENSP00000357980	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:htra1_human(display_long)|uniprotkb:HTRA1(gene name)|psi-mi:HTRA1(display_short)|uniprotkb:HTRA(gene name synonym)|uniprotkb:PRSS11(gene name synonym)|uniprotkb:High-temperature requirement A serine peptidase 1(gene name synonym)|uniprotkb:L56(gene name synonym)|uniprotkb:Serine protease 11(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973131|imex:IM-28944-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002766.1|ensembl:ENSG00000166033(gene)|ensembl:ENST00000368984(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097187"(dentinogenesis)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|rcsb pdb:2JOA|rcsb pdb:2YTW|rcsb pdb:3NUM|rcsb pdb:3NWU|rcsb pdb:3NZI|rcsb pdb:3TJN|rcsb pdb:3TJO|rcsb pdb:3TJQ|rcsb pdb:6Z0E|rcsb pdb:6Z0X|rcsb pdb:6Z0Y|reactome:R-HSA-1474228|dip:DIP-33195N	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:28.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:Y7lT7nyI9N/3imHOz8Ng+Zagf509606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:jRR1kWj8pxrJWrVTJ+naOZZ/gcw	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:365-480	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N448	uniprotkb:P59637	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973161|imex:IM-28944-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:59.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:7RQEq8Xh/nsGpGKSqHEqTwQ5pyI	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:334-426	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15018	uniprotkb:P59637	intact:EBI-310669|uniprotkb:Q9BXD4|intact:EBI-28970957|ensembl:ENSP00000402033	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:pdzd2_human(display_long)|uniprotkb:PDZD2(gene name)|psi-mi:PDZD2(display_short)|uniprotkb:AIPC(gene name synonym)|uniprotkb:KIAA0300(gene name synonym)|uniprotkb:PDZK3(gene name synonym)|uniprotkb:PDZ domain-containing protein 3(gene name synonym)|uniprotkb:Activated in prostate cancer protein(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973191|imex:IM-28944-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000402033|refseq:NP_835260.2|ensembl:ENSG00000133401(gene)|ensembl:ENST00000438447(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|refseq:XP_011512297.1	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:57.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:C4VqQO4qKBodoVaj+22PX7B+FiY9606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:l+/azMg9c6/zE3nI+923k481uf4	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:2741-2839	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TEW0	uniprotkb:P59637	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973176|imex:IM-28944-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:55.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rigid:jFNXa8TKBGFUGyJCuS0ic7rnGno	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:582-685	biotin tag:n-n|sufficient binding region:65-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N448	uniprotkb:K9N5R3	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	intact:EBI-26374535	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973338|imex:IM-28944-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:77.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:6G0dtEamXv/XrFyk77XB+/mI1VA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:334-426	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92743	uniprotkb:K9N5R3	intact:EBI-352256|uniprotkb:Q9UNS5|uniprotkb:D3DRE4|ensembl:ENSP00000357980	intact:EBI-26374535	psi-mi:htra1_human(display_long)|uniprotkb:HTRA1(gene name)|psi-mi:HTRA1(display_short)|uniprotkb:HTRA(gene name synonym)|uniprotkb:PRSS11(gene name synonym)|uniprotkb:High-temperature requirement A serine peptidase 1(gene name synonym)|uniprotkb:L56(gene name synonym)|uniprotkb:Serine protease 11(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973323|imex:IM-28944-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002766.1|ensembl:ENSG00000166033(gene)|ensembl:ENST00000368984(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097187"(dentinogenesis)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|rcsb pdb:2JOA|rcsb pdb:2YTW|rcsb pdb:3NUM|rcsb pdb:3NWU|rcsb pdb:3NZI|rcsb pdb:3TJN|rcsb pdb:3TJO|rcsb pdb:3TJQ|rcsb pdb:6Z0E|rcsb pdb:6Z0X|rcsb pdb:6Z0Y|reactome:R-HSA-1474228|dip:DIP-33195N	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:18.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:Y7lT7nyI9N/3imHOz8Ng+Zagf509606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:AIabiwMB83bBvxj/0NcUfFJaBIs	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:365-480	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TEW0	uniprotkb:K9N5R3	intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47	intact:EBI-26374535	psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973353|imex:IM-28944-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:50.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:tmx6j05OPRPJ1EwtJVPFtwiM5dc	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:582-685	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12923	uniprotkb:K9N5R3	intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249	intact:EBI-26374535	psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973293|imex:IM-28944-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:82.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:63CakplbfQ+8kq254QSUdpn5Pcw	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1779-1873	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96L92	uniprotkb:K9N5R3	intact:EBI-2514865|ensembl:ENSP00000400333|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1	intact:EBI-26374535	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973368|imex:IM-28944-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143376(gene)|ensembl:ENST00000458013(transcript)|go:"GO:0001770"(establishment of natural killer cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|refseq:NP_001317652.1|refseq:NP_112180.4|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR000159(Ras-association)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|interpro:IPR001478(PDZ/DHR/GLGF)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:25.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:T5/8ySl2GK63qXni5mVHgvQceyI	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:40-141	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07157	uniprotkb:K9N5R3	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	intact:EBI-26374535	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973278|imex:IM-28944-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:48.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:K/pIMsCn1fSLwkpCNF96lLX4kCE	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:184-264	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P83110	uniprotkb:K9N5R3	intact:EBI-2867394|uniprotkb:Q7Z7A2|ensembl:ENSP00000303766	intact:EBI-26374535	psi-mi:htra3_human(display_long)|uniprotkb:HTRA3(gene name)|psi-mi:HTRA3(display_short)|uniprotkb:PRSP(gene name synonym)|uniprotkb:High-temperature requirement factor A3(gene name synonym)|uniprotkb:Pregnancy-related serine protease(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973399|imex:IM-28944-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284488.1|refseq:NP_444272.1|ensembl:ENSG00000170801(gene)|ensembl:ENST00000307358(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR036034|interpro:IPR036058|interpro:IPR041489|rcsb pdb:2P3W|rcsb pdb:4RI0	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.2x10^-6(molar)	2021/05/11	2021/05/12	rogid:oJfuPj+xPZ+WkCu+VlJeqJAr/3k9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:qE6qGUiLh9Y+GUeThQwWnavmgUo	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:353-453	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96RT1	uniprotkb:K9N5R3	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9	intact:EBI-26374535	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973414|imex:IM-28944-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.9x10^-6(molar)	2021/05/11	2021/05/12	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:S6eJxrsRXSbxufWJ6fxFDuAeOLA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1314-1412	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15018	uniprotkb:K9N5R3	intact:EBI-310669|uniprotkb:Q9BXD4|intact:EBI-28970957|ensembl:ENSP00000402033	intact:EBI-26374535	psi-mi:pdzd2_human(display_long)|uniprotkb:PDZD2(gene name)|psi-mi:PDZD2(display_short)|uniprotkb:AIPC(gene name synonym)|uniprotkb:KIAA0300(gene name synonym)|uniprotkb:PDZK3(gene name synonym)|uniprotkb:PDZ domain-containing protein 3(gene name synonym)|uniprotkb:Activated in prostate cancer protein(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973429|imex:IM-28944-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000402033|refseq:NP_835260.2|ensembl:ENSG00000133401(gene)|ensembl:ENST00000438447(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|refseq:XP_011512297.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:8.9x10^-6(molar)	2021/05/11	2021/05/13	rogid:C4VqQO4qKBodoVaj+22PX7B+FiY9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:nFwggZFS373olebqGDT/uZSq66M	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:326-424	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UL8	uniprotkb:K9N5R3	intact:EBI-311035|uniprotkb:O60434|uniprotkb:O60510|uniprotkb:Q86UI7|uniprotkb:Q9NP44|uniprotkb:Q9UDQ5|uniprotkb:Q9UDU1|uniprotkb:A4D1C1|uniprotkb:A7E2C3|intact:EBI-28973920|ensembl:ENSP00000346151	intact:EBI-26374535	psi-mi:magi2_human(display_long)|uniprotkb:MAGI2(gene name)|psi-mi:MAGI2(display_short)|uniprotkb:KIAA0705(gene name synonym)|uniprotkb:ACVRINP1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein A(gene name synonym)|uniprotkb:AIP1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973444|imex:IM-28944-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000346151|ensembl:ENST00000419488|ensembl:ENSP00000405766|refseq:NP_036433.2|refseq:NP_001288057.1|ensembl:ENSG00000187391(gene)|ensembl:ENST00000354212(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030036|interpro:IPR036020|interpro:IPR036034|mint:Q86UL8|rcsb pdb:1UEP|rcsb pdb:1UEQ|rcsb pdb:1UEW|rcsb pdb:1UJV|rcsb pdb:1WFV|reactome:R-HSA-373753|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043113"(receptor clustering)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:17.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:/uTMSMqB1wrlyHj2P9OVVBCpWcY9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:UWGrEDS/+Opp2S0O43k/s9PMak8	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1141-1216	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H8Y8	uniprotkb:K9N5R3	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	intact:EBI-26374535	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973459|imex:IM-28944-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:18.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:Bz9dGaRTDQHg9DGMiHKsksmuiAw	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1-208	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49796-4	uniprotkb:K9N5R3	intact:EBI-12006708|ensembl:ENSP00000340284	intact:EBI-26374535	psi-mi:p49796-4(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)|uniprotkb:1(isoform synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973474|imex:IM-28944-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2107809(isoform-parent)|uniprotkb:P49796-4(isoform-parent)|ensembl:ENSG00000138835(gene)|ensembl:ENST00000343817(transcript)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:22.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:zNU/4JDwwQc3k/mBcR+MpL85sHA9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:v2SR7Aek5rfl5cclEQzX5PfOpBc	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:12-97	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96QZ7	uniprotkb:K9N5R3	intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188	intact:EBI-26374535	psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973490|imex:IM-28944-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:23.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:bEJYLGLJCipq3G8kr0qpXSF0N3k	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1146-1238	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95049	uniprotkb:K9N5R3	intact:EBI-1171427|uniprotkb:A6NFP3|uniprotkb:Q32N01|uniprotkb:B3KR73|uniprotkb:B4E2W6|uniprotkb:F5H2X0|uniprotkb:F5H4S9|uniprotkb:B3KXZ0|uniprotkb:K7EK22|intact:EBI-10970160|ensembl:ENSP00000439278	intact:EBI-26374535	psi-mi:zo3_human(display_long)|uniprotkb:Zonula occludens protein 3(gene name synonym)|uniprotkb:Zona occludens protein 3(gene name synonym)|uniprotkb:Tight junction protein 3(gene name synonym)|uniprotkb:TJP3(gene name)|psi-mi:TJP3(display_short)|uniprotkb:ZO3(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973506|imex:IM-28944-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001254489.1|refseq:NP_001254490.1|ensembl:ENSG00000105289(gene)|ensembl:ENST00000541714(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005420(Zona occludens protein ZO-3)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|rcsb pdb:3KFV|go:"GO:0005923"(bicellular tight junction)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:24.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:bJciuPizUo/lOq89solMYusjm009606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:VMcuL1eBi9SdHndwiolArrUwa7M	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:373-482	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02410	uniprotkb:K9N5R3	intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381	intact:EBI-26374535	psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973521|imex:IM-28944-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:26.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:9VCEM0oP/KewPL+ofvL1b8p0hV8	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:743-822	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQQ3	uniprotkb:K9N5R3	intact:EBI-2561458|uniprotkb:Q3SYG7|uniprotkb:Q96H42|uniprotkb:Q8N272|uniprotkb:B3KWC8|ensembl:ENSP00000313869	intact:EBI-26374535	psi-mi:gors1_human(display_long)|uniprotkb:GORASP1(gene name)|psi-mi:GORASP1(display_short)|uniprotkb:GOLPH5(gene name synonym)|uniprotkb:GRASP65(gene name synonym)|uniprotkb:Golgi reassembly-stacking protein of 65 kDa(gene name synonym)|uniprotkb:Golgi peripheral membrane protein p65(gene name synonym)|uniprotkb:Golgi phosphoprotein 5(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973536|imex:IM-28944-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114105.1|refseq:NP_001265718.1|refseq:NP_001265719.1|ensembl:ENSG00000114745(gene)|ensembl:ENST00000319283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:4REY|rcsb pdb:6G8T|rcsb pdb:6G8W|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:40.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:gCTXn0H+UPamtVxyvChrMrcQvCA9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:4fiPG0p39NEBmxq43oGcVcs2aCA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1-208	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UQ26	uniprotkb:K9N5R3	intact:EBI-1756749|uniprotkb:O43413|uniprotkb:Q86XL9|uniprotkb:Q8IWV9|uniprotkb:Q8IWW1|uniprotkb:B3KX91|uniprotkb:F8WD47|intact:EBI-28973118	intact:EBI-26374535	psi-mi:rims2_human(display_long)|uniprotkb:RIMS2(gene name)|psi-mi:RIMS2(display_short)|uniprotkb:KIAA0751(gene name synonym)|uniprotkb:RAB3IP3(gene name synonym)|uniprotkb:RIM2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)|uniprotkb:Rab-3-interacting protein 3(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973551|imex:IM-28944-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269810.1|refseq:NP_001269811.1|ensembl:ENST00000262231|ensembl:ENSP00000262231|ensembl:ENSG00000176406|ensembl:ENST00000339750|ensembl:ENSP00000342051|ensembl:ENSP00000427018|ensembl:ENST00000507740|ensembl:ENSP00000423559|ensembl:ENST00000504942|refseq:NP_001093587.1|refseq:NP_055492.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|rcsb pdb:1V27|rcsb pdb:1WFG|interpro:IPR039032|interpro:IPR030631|interpro:IPR035892|interpro:IPR036034|interpro:IPR041282|interpro:IPR041489|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:43.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:r+m/eB+6yczGhwv4pxI6vzG/RHc9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:AcxmuaEIBVrFRDeF7a9bOhmyoS8	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:637-758	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UR5	uniprotkb:K9N5R3	intact:EBI-1043236|uniprotkb:B7Z3S3|uniprotkb:E7EX08|uniprotkb:E9PHR1|uniprotkb:Q5JY21|uniprotkb:O15048|uniprotkb:Q8TDY9|uniprotkb:Q8TDZ5|uniprotkb:Q9HBA1|uniprotkb:Q9HBA2|uniprotkb:Q9HBA3|uniprotkb:Q9HBA4|uniprotkb:Q9HBA5|uniprotkb:Q9HBA6|ensembl:ENSP00000428417|intact:EBI-1752690|intact:EBI-1957901|uniprotkb:A7MBN6|uniprotkb:Q5JY25|uniprotkb:Q5SZK1|uniprotkb:B7Z6S2|uniprotkb:E9PCB7|uniprotkb:E9PCZ1|uniprotkb:B7Z2M0|uniprotkb:B7Z2Q9|uniprotkb:E9PF48|uniprotkb:E9PHF5	intact:EBI-26374535	psi-mi:rims1_human(display_long)|uniprotkb:Rab-3-interacting molecule 1(gene name synonym)|uniprotkb:RIMS1(gene name)|psi-mi:RIMS1(display_short)|uniprotkb:KIAA0340(gene name synonym)|uniprotkb:RIM1(gene name synonym)|uniprotkb:Nbla00761(orf name)|uniprotkb:RAB3IP2(gene name synonym)|uniprotkb:Rab-3-interacting protein 2(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973566|imex:IM-28944-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000079841(gene)|ensembl:ENST00000521978(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046903"(secretion)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050896"(response to stimulus)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|rcsb pdb:2CSS|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-888590|refseq:NP_055804.2|refseq:NP_001161882.1|refseq:XP_011533917.2|refseq:NP_001161883.1|refseq:NP_001161879.1|refseq:NP_001161880.1|refseq:NP_001161881.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:43.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:hWekc+DUzy3KU1S8wADJedZk/SY9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:YZS4NQeycLizg1gEXOEfP4+4GwY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:584-692	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14CM0	uniprotkb:K9N5R3	intact:EBI-311279|uniprotkb:O15032|uniprotkb:A8K0X9|intact:EBI-28986006|ensembl:ENSP00000370057	intact:EBI-26374535	psi-mi:frpd4_human(display_long)|uniprotkb:FRMPD4(gene name)|psi-mi:FRMPD4(display_short)|uniprotkb:KIAA0316(gene name synonym)|uniprotkb:PDZD10(gene name synonym)|uniprotkb:PDZK10(gene name synonym)|uniprotkb:PDZ domain-containing protein 10(gene name synonym)|uniprotkb:PSD-95-interacting regulator of spine morphogenesis(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973581|imex:IM-28944-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055543.2|go:"GO:0032991"(protein-containing complex)|go:"GO:0043197"(dendritic spine)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|interpro:IPR041779|mint:Q14CM0|rcsb pdb:4WND|rcsb pdb:4WNE|rcsb pdb:4WNF|rcsb pdb:4WNG|rcsb pdb:7BYJ|ensembl:ENSG00000169933(gene)|ensembl:ENST00000380682(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005856"(cytoskeleton)|ensembl:ENSP00000370057	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:43.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:i30LCbRkJu6iYViBTLtHqGCFdXA9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:nG5/bl8pjEH0aZ5Qmo377888j4U	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:67-160	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12923-4	uniprotkb:K9N5R3	intact:EBI-355268|ensembl:ENSP00000394794|ensembl:ENSP00000426626	intact:EBI-26374535	psi-mi:q12923-4(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973731|imex:IM-28944-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-355227(ptn13_human)|ensembl:ENSG00000163629(gene)|ensembl:ENST00000436978(transcript)|ensembl:ENST00000511467(transcript)|uniprotkb:Q12923-4(isoform-parent)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	isoform-comment:May be due to a competing donor splice site.	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:46.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:jqN+aJInF5s+MFrO7FTQRfg4vgE9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:OlHuONpFCOznxtDS7bGgL4TEQqA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1362-1460	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NI35	uniprotkb:K9N5R3	intact:EBI-724390|uniprotkb:O15249|uniprotkb:O43742|uniprotkb:O60833|uniprotkb:Q5VUA5|uniprotkb:Q5VUA6|uniprotkb:Q5VUA7|uniprotkb:Q5VUA8|uniprotkb:Q5VUA9|uniprotkb:Q5VUB0|uniprotkb:Q8WU78|uniprotkb:Q9H3N9|ensembl:ENSP00000360200	intact:EBI-26374535	psi-mi:inadl_human(display_long)|uniprotkb:CIPP(gene name synonym)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:PATJ(gene name)|psi-mi:PATJ(display_short)|uniprotkb:INADL(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973747|imex:IM-28944-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000360200|ensembl:ENST00000484937|ensembl:ENSP00000433669|ensembl:ENSG00000132849(gene)|ensembl:ENST00000371158(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q8NI35|rcsb pdb:1VF6|rcsb pdb:2D92|rcsb pdb:2DAZ|rcsb pdb:2DB5|rcsb pdb:2DLU|rcsb pdb:2DM8|rcsb pdb:2DMZ|rcsb pdb:2EHR|rcsb pdb:4Q2N|rcsb pdb:6IRD|reactome:R-HSA-420029	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:61.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:brzBKZb3r39w13Ds5X/1jB6YMyM9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:HEfsne9dVovTy0vCYDvEt1QI3mA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1530-1615	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T5U3	uniprotkb:K9N5R3	intact:EBI-1642518|uniprotkb:Q8NI19|uniprotkb:Q0VF98|uniprotkb:Q7Z3P7|uniprotkb:Q8N3A2|uniprotkb:Q8TBV5|uniprotkb:Q9P2C3|ensembl:ENSP00000379709	intact:EBI-26374535	psi-mi:rhg21_human(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 21(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973765|imex:IM-28944-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065875.3|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9013148|ensembl:ENSG00000107863(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051645"(Golgi localization)|ensembl:ENST00000396432(transcript)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|mint:Q5T5U3|rcsb pdb:2DHJ|rcsb pdb:2J59|rcsb pdb:2YUY|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9013106|refseq:XP_005252599.1|refseq:XP_016871948.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:63.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:wAGV1HiA3g66rAqehhiEjBRB+N0	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:47-159	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N448	uniprotkb:K9N5R3	intact:EBI-2340947|uniprotkb:Q6ZMH2|uniprotkb:Q5W0P0|uniprotkb:Q96SH4|ensembl:ENSP00000325929|ensembl:ENSP00000497224	intact:EBI-26374535	psi-mi:lnx2_human(display_long)|uniprotkb:LNX2(gene name)|psi-mi:LNX2(display_short)|uniprotkb:PDZRN1(gene name synonym)|uniprotkb:Numb-binding protein 2(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 1(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973783|imex:IM-28944-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_699202.1|refseq:XP_016875923.1|ensembl:ENSG00000139517(gene)|ensembl:ENST00000316334(transcript)|ensembl:ENST00000649248(transcript)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8N448|rcsb pdb:2VWR|rcsb pdb:5DIN|rcsb pdb:5E11|rcsb pdb:5E1Y|rcsb pdb:5E21|rcsb pdb:5E22	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:64.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:cIS5t4XkbnIgelDlUc692nI285g9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:6G0dtEamXv/XrFyk77XB+/mI1VA	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:223-326	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TF65	uniprotkb:K9N5R3	intact:EBI-712067|ensembl:ENSP00000359795|uniprotkb:Q8IYD3|uniprotkb:Q9NXS7	intact:EBI-26374535	psi-mi:gipc2_human(display_long)|uniprotkb:GIPC2(gene name)|psi-mi:GIPC2(display_short)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973799|imex:IM-28944-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137960(gene)|ensembl:ENST00000370759(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|rcsb pdb:3GGE|refseq:NP_060125.4|refseq:NP_001291654.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:65.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:tmXszDsKNzUfki6x7swoLDtaow89606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:frMRgBM89cGI/PUJ3csTCr8lPHQ	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:112-203	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95049	uniprotkb:K9N5R3	intact:EBI-1171427|uniprotkb:A6NFP3|uniprotkb:Q32N01|uniprotkb:B3KR73|uniprotkb:B4E2W6|uniprotkb:F5H2X0|uniprotkb:F5H4S9|uniprotkb:B3KXZ0|uniprotkb:K7EK22|intact:EBI-10970160|ensembl:ENSP00000439278	intact:EBI-26374535	psi-mi:zo3_human(display_long)|uniprotkb:Zonula occludens protein 3(gene name synonym)|uniprotkb:Zona occludens protein 3(gene name synonym)|uniprotkb:Tight junction protein 3(gene name synonym)|uniprotkb:TJP3(gene name)|psi-mi:TJP3(display_short)|uniprotkb:ZO3(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973824|imex:IM-28944-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001254489.1|refseq:NP_001254490.1|ensembl:ENSG00000105289(gene)|ensembl:ENST00000541714(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005420(Zona occludens protein ZO-3)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|rcsb pdb:3KFV|go:"GO:0005923"(bicellular tight junction)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:68.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:bJciuPizUo/lOq89solMYusjm009606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:VMcuL1eBi9SdHndwiolArrUwa7M	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1-109	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P2F8	uniprotkb:K9N5R3	intact:EBI-2797173|uniprotkb:Q5VXR8|uniprotkb:Q641Q4|uniprotkb:Q5VXR7|uniprotkb:Q9H9F6|uniprotkb:Q96DZ3|uniprotkb:Q8NA38|intact:EBI-2880635|uniprotkb:Q2TV88|ensembl:ENSP00000262861|ensembl:ENSP00000355589|ensembl:ENSP00000502693	intact:EBI-26374535	psi-mi:si1l2_human(display_long)|uniprotkb:KIAA1389(gene name synonym)|uniprotkb:SIPA1L2(gene name)|psi-mi:SIPA1L2(display_short)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973846|imex:IM-28944-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011542545.1|refseq:NP_065859.3|refseq:XP_005273268.1|refseq:XP_005273269.1|refseq:XP_005273270.1|ensembl:ENSG00000116991(gene)|ensembl:ENST00000262861(transcript)|ensembl:ENST00000366630(transcript)|ensembl:ENST00000674635(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031203|interpro:IPR035974|interpro:IPR036034|refseq:XP_016857385.1	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:69.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:qmmHDrxjsNJ1RR8ixhGC0ohDCFM9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid://0CnwjzXf1P+fbo7UUN9KtDr5A	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:943-1027	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H987	uniprotkb:K9N5R3	intact:EBI-7964669|uniprotkb:Q68A20|intact:MINT-7969997|uniprotkb:A5PKV9|ensembl:ENSP00000378289	intact:EBI-26374535	psi-mi:syp2l_human(display_long)|uniprotkb:SYNPO2L(gene name)|psi-mi:SYNPO2L(display_short)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973869|imex:IM-28944-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001107605.1|refseq:NP_079151.2|ensembl:ENSG00000166317(gene)|ensembl:ENST00000394810(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	comment:mint	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:72.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:RfzOMjs9ugrrB6aUjoGR7qOgyd49606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:JFdROrRFNOEossH35RIEIVSXWAI	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1-89	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00560	uniprotkb:K9N5R3	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	intact:EBI-26374535	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973888|imex:IM-28944-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:80.0x10^-6(molar)	2021/05/11	2021/05/12	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rigid:fslOmxx0wMaTEA1XUafsRG/r8aY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:111-198	biotin tag:n-n|sufficient binding region:71-82	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:K9N5R3	uniprotkb:Q96NW7	intact:EBI-26374535	intact:EBI-524275|uniprotkb:Q5VXC2|uniprotkb:Q5VXC3|uniprotkb:Q68D07|uniprotkb:Q8WX20|uniprotkb:Q9P2I2|uniprotkb:Q86VE8	psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:lrrc7_human(display_long)|uniprotkb:Protein LAP1(gene name synonym)|uniprotkb:Densin-180(gene name synonym)|uniprotkb:LRRC7(gene name)|psi-mi:LRRC7(display_short)|uniprotkb:KIAA1365(gene name synonym)|uniprotkb:LAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973930|imex:IM-28944-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379	interpro:IPR003591(Leucine-rich repeat, typical subtype)|rcsb pdb:6X5G|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043113"(receptor clustering)|go:"GO:0043194"(axon initial segment)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR036034|reactome:R-HSA-6798695|interpro:IPR032675|refseq:NP_065845.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001478(PDZ/DHR/GLGF)|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736	-	-	-	figure legend:Figure 2,  Table 1, Supp. Table 1.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:41.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:faXUcv0htunomX+0C6MTJT2AJu41263720	rogid:8HUVcF8vycpMbC6o7GWT+u9iPu49606	rigid:/DoG2NhpPJb99tVHGWH7K0joHbA	false	biotin tag:n-n|sufficient binding region:71-82	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:1445-1536	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07157	uniprotkb:P0DTC3	intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6	intact:EBI-25475894	psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26973960|imex:IM-28944-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2	go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719	-	-	-	figure legend:Figure 3B, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:29.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606	rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049	rigid:1BV0oIpgSNFkImP0qsqI0xPwqCM	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:184-264	biotin tag:n-n|sufficient binding region:264-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UT5-2	uniprotkb:P0DTC3	intact:EBI-8299496|intact:MINT-1773278|ensembl:ENSP00000347742	intact:EBI-25475894	psi-mi:q86ut5-2(display_long)|uniprotkb:PDZD3(gene name)|psi-mi:PDZD3(display_short)|uniprotkb:IKEPP(gene name synonym)|uniprotkb:Intestinal and kidney-enriched PDZ protein(gene name synonym)|uniprotkb:NHERF4(gene name synonym)|uniprotkb:Natrium-phosphate cotransporter IIa C-terminal-associated protein 2(gene name synonym)|uniprotkb:PDZ domain-containing protein 2(gene name synonym)|uniprotkb:PDZ domain-containing protein 3(gene name synonym)|uniprotkb:PDZK2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 4(gene name synonym)|uniprotkb:DLNB27(orf name)	psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974079|imex:IM-28944-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8744528(isoform-parent)|ensembl:ENSG00000172367(gene)|ensembl:ENST00000355547(transcript)	go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719	-	comment:mint	-	figure legend:Figure 3B, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:39.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:0NqvlKTxu9qBGZxUQPY1vsfPG4E9606	rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049	rigid:if9Maq0wuH6bTeAKHUQLYtIydFE	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:37-142	biotin tag:n-n|sufficient binding region:264-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T2W1	uniprotkb:P0DTC3	intact:EBI-349819|uniprotkb:O60450|uniprotkb:Q5T5P6|uniprotkb:Q9BQ41|ensembl:ENSP00000342143|ensembl:ENSP00000394485|uniprotkb:B4DPB9|uniprotkb:E7EU02	intact:EBI-25475894	psi-mi:nhrf3_human(display_long)|uniprotkb:PDZK1(gene name)|psi-mi:PDZK1(display_short)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:CAP70(gene name synonym)|uniprotkb:NHERF3(gene name synonym)|uniprotkb:PDZD1(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)	psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974095|imex:IM-28944-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188254.1|refseq:NP_002605.2|ensembl:ENSG00000174827(gene)|rcsb pdb:3TMH|rcsb pdb:4Q2P|rcsb pdb:6EZI|ensembl:ENST00000344770(transcript)|ensembl:ENST00000417171(transcript)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|mint:Q5T2W1|rcsb pdb:2EEI|rcsb pdb:2EEJ|rcsb pdb:2VSP|refseq:NP_001188255.1|refseq:XP_016856953.1	go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719	-	-	-	figure legend:Figure 3B, Supp. Table 1|comment:"The sequence given for PDZ domain from  NHERF3_4 (gene=PDZK1) also gives a 100% match to    Uniprot identifier A8MUH7 (PDZ1P_HUMAN) aas 258-342,  a possible pseudogene product."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:53.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:sU0SZ8m9Or0LFmLo9dh6B7RBJWs9606	rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049	rigid:gkxW92s+bPXQ8bSuP/JtEd/Cjj8	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:375-459	biotin tag:n-n|sufficient binding region:264-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49796-4	uniprotkb:P0DTC3	intact:EBI-12006708|ensembl:ENSP00000340284	intact:EBI-25475894	psi-mi:p49796-4(display_long)|uniprotkb:RGS3(gene name)|psi-mi:RGS3(display_short)|uniprotkb:1(isoform synonym)	psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974113|imex:IM-28944-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2107809(isoform-parent)|uniprotkb:P49796-4(isoform-parent)|ensembl:ENSG00000138835(gene)|ensembl:ENST00000343817(transcript)	go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719	-	-	-	figure legend:Figure 3B, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:67.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:zNU/4JDwwQc3k/mBcR+MpL85sHA9606	rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049	rigid:ic0PC6jw19RJDlAfE38UIyGh9Ew	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:12-97	biotin tag:n-n|sufficient binding region:264-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TEW8	uniprotkb:P0DTC3	intact:EBI-2861929|uniprotkb:Q8IUC9|uniprotkb:Q96NX6|uniprotkb:Q96NX7|uniprotkb:Q96DK9|uniprotkb:Q8IUC7|uniprotkb:Q96N09|uniprotkb:Q96Q29|uniprotkb:E9PE87|ensembl:ENSP00000385848	intact:EBI-25475894	psi-mi:par3l_human(display_long)|uniprotkb:PARD3B(gene name)|psi-mi:PARD3B(display_short)|uniprotkb:ALS2CR19(gene name synonym)|uniprotkb:PAR3B(gene name synonym)|uniprotkb:PAR3L(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein(gene name synonym)|uniprotkb:PAR3-beta(gene name synonym)|uniprotkb:Partitioning defective 3-like protein(gene name synonym)	psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974132|imex:IM-28944-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476518.4|refseq:NP_689739.4|refseq:NP_995585.2|refseq:NP_001289698.1|dip:DIP-42276N|ensembl:ENSG00000116117(gene)|ensembl:ENST00000406610(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW8	go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719	-	-	-	figure legend:Figure 3B, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:79.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:68iR8w+iTdxuwBYs+HGumldBFQs9606	rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049	rigid:A303v1wbo6JSSHMotr22vnMdtLE	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:184-299	biotin tag:n-n|sufficient binding region:264-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IUC4	uniprotkb:P0DTC9	intact:EBI-1043535|uniprotkb:Q8N3T7|uniprotkb:Q8N9D6|uniprotkb:Q8NE33|uniprotkb:Q96RU1|uniprotkb:B4DUS7|ensembl:ENSP00000254260|uniprotkb:B2RCG8|uniprotkb:B3KUY8	intact:EBI-25475856	psi-mi:rhpn2_human(display_long)|uniprotkb:GTP-Rho-binding protein 2(gene name synonym)|uniprotkb:76 kDa RhoB effector protein(gene name synonym)|uniprotkb:p76RBE(gene name synonym)|uniprotkb:RHPN2(gene name)|psi-mi:RHPN2(display_short)	psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974147|imex:IM-28944-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131941(gene)|ensembl:ENST00000254260(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004328(BRO1)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR036034|interpro:IPR036274|interpro:IPR038499|mint:Q8IUC4|rcsb pdb:2VSV|reactome:R-HSA-5666185|reactome:R-HSA-8980692|reactome:R-HSA-9013026|refseq:NP_149094.3	rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786	-	-	-	figure legend:Figure 3B, Supp. table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:aYGU5645tT3gS0yOEMFMxMDCS9U9606	rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049	rigid:i+cY6JENVmef5S8nU/ifRR9hkgY	false	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:506-606	biotin tag:n-n|sufficient binding region:408-419	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DTC9	uniprotkb:O14908	intact:EBI-25475856	intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747	psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)	psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Caillet-Saguy et al. (2021)	imex:IM-28944|pubmed:33864728	taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26974167|imex:IM-28944-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786	refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N	-	-	-	figure legend:Figure 3B, Supp. table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:36.0x10^-6(molar)	2021/05/11	2021/05/13	rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049	rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606	rigid:gxciFdAGjyOmq2+9+svSP4nEGjI	false	sufficient binding region:408-419|biotin tag:n-n	his tag:n-n|maltose binding protein tag:n-n|sufficient binding region:128-223	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)