#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30153 uniprotkb:P67775-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-16765970|ensembl:ENSP00000418447 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27019145|wwpdb:7K36|emdb:EMD-22650|imex:IM-29262-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) - - - figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q13033-2 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27019145|wwpdb:7K36|emdb:EMD-22650|imex:IM-29262-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) - - - figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - 1 4 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q5VSL9-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1773601|ensembl:ENSP00000358810 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27019145|wwpdb:7K36|emdb:EMD-22650|imex:IM-29262-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) - - - figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q9Y3A3-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-713946|ensembl:ENSP00000315702 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27019145|wwpdb:7K36|emdb:EMD-22650|imex:IM-29262-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) - - - figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:P67775-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-16765970|ensembl:ENSP00000418447 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:"MI:0071"(molecular sieving) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27029017|imex:IM-29262-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) - - - figure legend:Fig. 1b, Supp. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q13033-2 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27029017|imex:IM-29262-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) - - - figure legend:Fig. 1b, Supp. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q5VSL9-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1773601|ensembl:ENSP00000358810 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27029017|imex:IM-29262-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) - - - figure legend:Fig. 1b, Supp. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P30153 uniprotkb:Q9Y3A3-1 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-713946|ensembl:ENSP00000315702 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0071"(molecular sieving) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27029017|imex:IM-29262-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) - - - figure legend:Fig. 1b, Supp. Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/03/30 2021/07/06 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false - - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5VSL9-1 uniprotkb:Q9Y3A3 intact:EBI-1773601|ensembl:ENSP00000358810 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27029047|imex:IM-29262-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Fig. 3d,e; Fig. 4c, 4f, Fig. 5c, extended Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|mutation decreasing interaction:427-427|mutation decreasing interaction:744-744|mutation decreasing interaction:131-131,134-134|mutation decreasing interaction:444-444|mutation decreasing interaction:462-462|mutation decreasing interaction:733-733|necessary binding region:796-837 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5VSL9-1 uniprotkb:Q13033 intact:EBI-1773601|ensembl:ENSP00000358810 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27029047|imex:IM-29262-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Fig. 3d,e; Fig. 4c, 4f, Fig. 5c, extended Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|mutation decreasing interaction:427-427|mutation decreasing interaction:744-744|mutation decreasing interaction:131-131,134-134|mutation decreasing interaction:444-444|mutation decreasing interaction:462-462|mutation decreasing interaction:733-733|necessary binding region:796-837 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5VSL9-1 uniprotkb:P67775 intact:EBI-1773601|ensembl:ENSP00000358810 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27029047|imex:IM-29262-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Fig. 3d,e; Fig. 4c, 4f, Fig. 5c, extended Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|mutation decreasing interaction:427-427|mutation decreasing interaction:744-744|mutation decreasing interaction:131-131,134-134|mutation decreasing interaction:444-444|mutation decreasing interaction:462-462|mutation decreasing interaction:733-733|necessary binding region:796-837 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5VSL9-1 uniprotkb:P30153 intact:EBI-1773601|ensembl:ENSP00000358810 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q5vsl9-1(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27029047|imex:IM-29262-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1773588(isoform-parent)|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig. 3d,e; Fig. 4c, 4f, Fig. 5c, extended Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|mutation decreasing interaction:427-427|mutation decreasing interaction:744-744|mutation decreasing interaction:131-131,134-134|mutation decreasing interaction:444-444|mutation decreasing interaction:462-462|mutation decreasing interaction:733-733|necessary binding region:796-837 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775-1 uniprotkb:Q9Y3A3 intact:EBI-16765970|ensembl:ENSP00000418447 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27030741|imex:IM-29262-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:186-186|flag tag:n-n|mutation disrupting interaction strength:209-209 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775-1 uniprotkb:Q5VSL9 intact:EBI-16765970|ensembl:ENSP00000418447 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27030741|imex:IM-29262-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:186-186|flag tag:n-n|mutation disrupting interaction strength:209-209 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775-1 uniprotkb:Q13033 intact:EBI-16765970|ensembl:ENSP00000418447 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27030741|imex:IM-29262-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:186-186|flag tag:n-n|mutation disrupting interaction strength:209-209 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775-1 uniprotkb:P30153 intact:EBI-16765970|ensembl:ENSP00000418447 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27030741|imex:IM-29262-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:186-186|flag tag:n-n|mutation disrupting interaction strength:209-209 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775-1 uniprotkb:P30153 intact:EBI-16765970|ensembl:ENSP00000418447 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:p67775-1(display_long)|uniprotkb:Replication protein C(gene name synonym)|uniprotkb:PP2Acalpha1(isoform synonym)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27031834|imex:IM-29262-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|intact:EBI-712311(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/10/05 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:glCg63hIjz1ar89upEmpH5aV39A false mutation:186-186|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30153 uniprotkb:Q9Y3A3 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031845|imex:IM-29262-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Fig 2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:15-15|flag tag:n-n|mutation with complex effect:19-19 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30153 uniprotkb:Q5VSL9 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031845|imex:IM-29262-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Fig 2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:15-15|flag tag:n-n|mutation with complex effect:19-19 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30153 uniprotkb:Q13033 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031845|imex:IM-29262-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Fig 2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:15-15|flag tag:n-n|mutation with complex effect:19-19 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P30153 uniprotkb:P67775 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031845|imex:IM-29262-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Fig 2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false mutation with complex effect:15-15|flag tag:n-n|mutation with complex effect:19-19 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P67775 uniprotkb:P30153 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27031864|imex:IM-29262-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig 2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/10/04 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:glCg63hIjz1ar89upEmpH5aV39A false - mutation:15-15|flag tag:n-n|mutation:19-19 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13033-2 uniprotkb:Q9Y3A3 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031875|imex:IM-29262-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Fig 2e, Extended Fig. 5A|comment:Interaction observed in STM1/3/4 knock-out cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false mutation with complex effect:116-116|mutation with complex effect:117-117|mutation with complex effect:121-121|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:Q5VSL9 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031875|imex:IM-29262-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Fig 2e, Extended Fig. 5A|comment:Interaction observed in STM1/3/4 knock-out cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false mutation with complex effect:116-116|mutation with complex effect:117-117|mutation with complex effect:121-121|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:P67775 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031875|imex:IM-29262-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Fig 2e, Extended Fig. 5A|comment:Interaction observed in STM1/3/4 knock-out cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false mutation with complex effect:116-116|mutation with complex effect:117-117|mutation with complex effect:121-121|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:P30153 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031875|imex:IM-29262-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig 2e, Extended Fig. 5A|comment:Interaction observed in STM1/3/4 knock-out cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false mutation with complex effect:116-116|mutation with complex effect:117-117|mutation with complex effect:121-121|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3-1 uniprotkb:Q13033 intact:EBI-713946|ensembl:ENSP00000315702 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27031917|imex:IM-29262-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Fig 5d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/10/05 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:dtBW/em7YqBRQiCyd+I0mOF9XZs false mutation:161-162,165-165|flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3-1 uniprotkb:Q5VSL9 intact:EBI-713946|ensembl:ENSP00000315702 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031939|imex:IM-29262-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Fig 5f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|necessary binding region:1-40|mutation with complex effect:161-162,165-165 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3-1 uniprotkb:Q13033 intact:EBI-713946|ensembl:ENSP00000315702 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031939|imex:IM-29262-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - - - figure legend:Fig 5f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|necessary binding region:1-40|mutation with complex effect:161-162,165-165 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3-1 uniprotkb:P67775 intact:EBI-713946|ensembl:ENSP00000315702 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031939|imex:IM-29262-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Fig 5f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|necessary binding region:1-40|mutation with complex effect:161-162,165-165 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3-1 uniprotkb:P30153 intact:EBI-713946|ensembl:ENSP00000315702 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q9y3a3-1(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031939|imex:IM-29262-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-713935(mob3_human)|ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Fig 5f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/07/10 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:A1EK4YWHyMM8WvL5u2T+FNLYPUc false flag tag:n-n|necessary binding region:1-40|mutation with complex effect:161-162,165-165 - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:Q9Y3A3 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031950|imex:IM-29262-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 - - - figure legend:Figs 2e, 5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2022/01/20 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false flag tag:?-?|necessary binding region:478..487-713..713(IPR001680)|mutation decreasing interaction strength:446-446|mutation decreasing interaction strength:120-120 - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13033-2 uniprotkb:Q5VSL9 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-1773588|uniprotkb:Q0V925|uniprotkb:Q5VSL8|uniprotkb:Q658K2|uniprotkb:Q6ZV31|uniprotkb:Q8N598|uniprotkb:Q96SN2|uniprotkb:Q9C0A2|ensembl:ENSP00000358810 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:strp1_human(display_long)|uniprotkb:STRIP1(gene name)|psi-mi:STRIP1(display_short)|uniprotkb:FAM40A(gene name synonym)|uniprotkb:KIAA1761(gene name synonym)|uniprotkb:Protein FAM40A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031950|imex:IM-29262-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) refseq:NP_001257697.1|refseq:NP_149079.2|dip:DIP-51621N|ensembl:ENSG00000143093(gene)|ensembl:ENST00000369795(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012486(N1221-like)|interpro:IPR021819|interpro:IPR040185|rcsb pdb:7K36 - - - figure legend:Figs 2e, 5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2022/01/20 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:Uaui+Ip8PKEWNWx8z7r9iknuvLk9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false flag tag:?-?|necessary binding region:478..487-713..713(IPR001680)|mutation decreasing interaction strength:446-446|mutation decreasing interaction strength:120-120 - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:P67775 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031950|imex:IM-29262-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Figs 2e, 5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2022/01/20 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false flag tag:?-?|necessary binding region:478..487-713..713(IPR001680)|mutation decreasing interaction strength:446-446|mutation decreasing interaction strength:120-120 - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q13033-2 uniprotkb:P30153 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-27031950|imex:IM-29262-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Figs 2e, 5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2022/01/20 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:pItpw5gAzlFAf9BPHWEjHg7amQg false flag tag:?-?|necessary binding region:478..487-713..713(IPR001680)|mutation decreasing interaction strength:446-446|mutation decreasing interaction strength:120-120 - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y3A3 uniprotkb:Q13033-2 intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0 intact:EBI-1053876|intact:EBI-27830295|ensembl:ENSP00000347909 psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name) psi-mi:q13033-2(display_long)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Jeong et al. (2021) imex:IM-29262|pubmed:33633399 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27101620|imex:IM-29262-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1 intact:EBI-1053857(strn3_human)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000355683(transcript)|uniprotkb:Q13033-2(isoform-parent) - - - figure legend:Fig 2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2021/03/30 2021/10/05 rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606 rogid:iNOxFiYQux+p8PBw6q2rZ6W1YRM9606 rigid:mo+Cz5QGicq+dkQctQkl1QCXGRo false - mutation:116-116|mutation:117-117|mutation:121-121|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot)