#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O15160-1	uniprotkb:O75575-1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-27043414|ensembl:ENSP00000378736	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:o75575-1(display_long)|uniprotkb:Calcitonin gene-related peptide-receptor component protein(gene name synonym)|uniprotkb:CRCP(gene name)|psi-mi:CRCP(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000241258(gene)|ensembl:ENST00000395326(transcript)|intact:EBI-2654687(isoform-parent)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:Xrb72g8eT2zV3NAFFyJXEBrloro9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P52434-1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-27050891|ensembl:ENSP00000392913	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:p52434-1(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|intact:EBI-359505(isoform-parent)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:O15160-1	uniprotkb:Q9NVU0-1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-6259429|ensembl:ENSP00000299853|ensembl:ENSP00000492263|ensembl:ENSP00000492514	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:q9nvu0-1(display_long)|uniprotkb:POLR3E(gene name)|psi-mi:POLR3E(display_short)|uniprotkb:KIAA1452(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 80 kDa polypeptide(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000058600(gene)|ensembl:ENSG00000284282(gene)|ensembl:ENST00000299853(transcript)|ensembl:ENST00000639550(transcript)|ensembl:ENST00000640588(transcript)|intact:EBI-2515048(isoform-parent)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:X4MAZK4RTaqr2QmPSRgaSnxD8zY9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:Q9NW08-1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-27043420	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:q9nw08-1(display_long)|uniprotkb:POLR3B(gene name)|psi-mi:POLR3B(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	uniprotkb:Q9NW08-1(isoform-parent)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:wHQRBDeUbMtfpXmUd/LkiE6GNaM9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:Q9Y535-1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-27050882|ensembl:ENSP00000347345|ensembl:ENSP00000379761|ensembl:ENSP00000385315	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:q9y535-1(display_long)|uniprotkb:KIAA1665(gene name synonym)|uniprotkb:POLR3H(gene name)|psi-mi:POLR3H(display_short)|uniprotkb:RPC8(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit H(gene name synonym)|uniprotkb:RNA polymerase III subunit 22.9 kDa subunit(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000100413(gene)|ensembl:ENST00000355209(transcript)|ensembl:ENST00000396504(transcript)|ensembl:ENST00000407461(transcript)|intact:EBI-2515065(isoform-parent)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:iZrzO9t581Oy9db2/+cpcy7uLL09606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P19388	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P61218	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-395180|uniprotkb:P41584|uniprotkb:Q6IAY3|ensembl:ENSP00000403852	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpab2_human(display_long)|uniprotkb:POLRF(gene name synonym)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide(gene name synonym)|uniprotkb:RPABC14.4(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym)|uniprotkb:RPC15(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_068809.1|interpro:IPR036161|mint:P61218|rcsb pdb:1QKL|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|ensembl:ENSG00000100142(gene)|ensembl:ENST00000442738(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|dip:DIP-32915N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:ljFKMfBLzZ3qRT27we7Gqdh0jv89606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P53803	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-395357|uniprotkb:Q6IBD4|ensembl:ENSP00000342889	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpab4_human(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym)|uniprotkb:RPB10alpha(gene name synonym)|uniprotkb:RNA polymerase II 7.0 kDa subunit(gene name synonym)|uniprotkb:ABC10-alpha(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_005025.1|ensembl:ENSG00000147669(gene)|ensembl:ENST00000353107(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|mint:P53803|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-72086|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32968N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P62875	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P0DPB6	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-359498|uniprotkb:Q9Y2S0|ensembl:ENSP00000302478|uniprotkb:Q5TBX2|uniprotkb:Q96BR3	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpac2_human(display_long)|uniprotkb:POLR1D(gene name)|psi-mi:POLR1D(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit D(gene name synonym)|uniprotkb:RPC16(gene name synonym)|uniprotkb:hRPA19(gene name synonym)|uniprotkb:AC19(gene name synonym)|uniprotkb:RNA polymerase I 16 kDa subunit(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	mint:P0DPB6|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|ensembl:ENSG00000186184(gene)|ensembl:ENST00000302979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603|refseq:NP_057056.1|refseq:XP_005266469.1	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:rDbtR47SoszVxupqkWmoxVTS4/E9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:Q9Y2Y1	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-11023785|ensembl:ENSP00000293860|uniprotkb:Q96S35|uniprotkb:Q1W6H4	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc10_human(display_long)|uniprotkb:POLR3K(gene name)|psi-mi:POLR3K(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit K(gene name synonym)|uniprotkb:RNA polymerase III 12.5 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:RPC11(gene name synonym)|uniprotkb:My010(orf name)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000161980(gene)|ensembl:ENST00000293860(transcript)|go:"GO:0003676"(nucleic acid binding)|refseq:NP_057394.3|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|mint:Q9Y2Y1|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:26KXQBPLU2oVOA1DSPeu4y5LjLM9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	flag tag:n-n	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:O14802	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:Q9BUI4	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-5452779|uniprotkb:O15317|uniprotkb:Q9Y3R6|ensembl:ENSP00000334564	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc3_human(display_long)|uniprotkb:POLR3C(gene name)|psi-mi:POLR3C(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit C(gene name synonym)|uniprotkb:RNA polymerase III 62 kDa subunit(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_001290385.1|dip:DIP-59078N|refseq:NP_006459.3|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR008806(RNA polymerase III Rpc82, C -terminal)|interpro:IPR013197(RNA polymerase III subunit RPC82-related, helix-turn-helix)|interpro:IPR036388|interpro:IPR039748|rcsb pdb:2XUB|rcsb pdb:2XV4|rcsb pdb:5AFQ|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|ensembl:ENSG00000186141(gene)|ensembl:ENST00000334163(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:2yQkAYuLbQEg5mNlIcFGbArFMOg9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:P05423	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:Q9H1D9	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-710067|uniprotkb:O15319|uniprotkb:A8K4C7|ensembl:ENSP00000366828	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc6_human(display_long)|uniprotkb:DNA-directed RNA polymerase III subunit F(gene name synonym)|uniprotkb:RNA polymerase III 39 kDa subunit(gene name synonym)|uniprotkb:POLR3F(gene name)|psi-mi:POLR3F(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	refseq:NP_001269455.1|refseq:NP_006457.2|dip:DIP-34646N|ensembl:ENSG00000132664(gene)|ensembl:ENST00000377603(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007832(RNA polymerase Rpc34)|interpro:IPR016049(RNA polymerase Rpc34-like)|interpro:IPR036388|interpro:IPR036390|mint:Q9H1D9|rcsb pdb:2DK5|rcsb pdb:2YU3|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:uqwUHkGa31Zl21767NrQK6nKbF09606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:O15160-1	uniprotkb:O15318	intact:EBI-5456225|ensembl:ENSP00000496044	intact:EBI-12362221|ensembl:ENSP00000421637|ensembl:ENSP00000498469|uniprotkb:A8MTH0	psi-mi:o15160-1(display_long)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:RPC40(gene name synonym)	psi-mi:rpc7_human(display_long)|uniprotkb:POLR3G(gene name)|psi-mi:POLR3G(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit G(gene name synonym)|uniprotkb:RNA polymerase III 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III 32 kDa apha subunit(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Wang et al. (2021)	pubmed:33558766|imex:IM-29127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27043431|emdb:EMD-30578|emdb:EMD-30577|wwpdb:7D58|wwpdb:7D59|imex:IM-29127-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055079(isoform-parent)|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)	ensembl:ENSG00000113356(gene)|ensembl:ENST00000504930(transcript)|ensembl:ENST00000651687(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR024661|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_006458.2|refseq:XP_005248461.1|refseq:XP_011541402.1|refseq:XP_011541403.1|refseq:XP_011541404.1|refseq:XP_016864446.1|dip:DIP-59079N	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line)	-	2021/07/07	2021/07/29	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rogid:lhoY+KmpqdrQUaB/04JHWT93H6Q9606	rigid:+G8hfDYjTuU6pOFWanltXVwA2cU	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)