#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6P9B9 uniprotkb:Q75QN2 intact:EBI-7600112|intact:MINT-4539005|uniprotkb:Q9C0G5|uniprotkb:Q8N6W5|ensembl:ENSP00000327889 intact:EBI-2340089|uniprotkb:Q5RKZ3|uniprotkb:Q6P1R5|uniprotkb:Q9NVS6|uniprotkb:Q7Z314|uniprotkb:Q9NWY7|uniprotkb:B2RN92|ensembl:ENSP00000430338 psi-mi:int5_human(display_long)|uniprotkb:INTS5(gene name)|psi-mi:INTS5(display_short)|uniprotkb:KIAA1698(gene name synonym) psi-mi:int8_human(display_long)|uniprotkb:INTS8(gene name)|psi-mi:INTS8(display_short)|uniprotkb:C8orf52(gene name synonym)|uniprotkb:Protein kaonashi-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617208|imex:IM-28724-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085131.1|ensembl:ENSG00000185085(gene)|ensembl:ENST00000330574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029444|interpro:IPR029445|interpro:IPR040316|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_060334.2|refseq:XP_016869108.1|ensembl:ENSG00000164941(gene)|ensembl:ENST00000523731(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR038751|rcsb pdb:7CUN|reactome:R-HSA-6807505 - function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint - figure legend:Fig. 1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2021/02/08 2021/02/08 rogid:2pirjs+e6eyNQayJnDp3NCjUhCk9606 rogid:9fEstP6mNqoKkTZGK70ANCMG7NM9606 rigid:bqjnq+CjCbRlhshfBkXznCDTU64 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:Q9NVM9 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617244|imex:IM-28724-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - - figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2021/02/08 2021/02/08 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:GslRmCP7sRL6+2ChM19lRFEV384 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:Q96N11 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-718667|uniprotkb:Q9BQ43|ensembl:ENSP00000340220 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:cg026_human(display_long)|uniprotkb:C7orf26(gene name)|psi-mi:C7orf26(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617244|imex:IM-28724-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_076972.2|refseq:NP_001289968.1|ensembl:ENSG00000146576(gene)|ensembl:ENST00000344417(transcript)|interpro:IPR027844 - - - figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2021/02/08 2021/02/08 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:BURe1wh7SN0dkYBaMmJ51w/W+qA9606 rigid:GslRmCP7sRL6+2ChM19lRFEV384 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:P07437 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617244|imex:IM-28724-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2021/02/08 2021/02/08 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 rigid:GslRmCP7sRL6+2ChM19lRFEV384 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P9B9 uniprotkb:Q75QN2 intact:EBI-7600112|intact:MINT-4539005|uniprotkb:Q9C0G5|uniprotkb:Q8N6W5|ensembl:ENSP00000327889 intact:EBI-2340089|uniprotkb:Q5RKZ3|uniprotkb:Q6P1R5|uniprotkb:Q9NVS6|uniprotkb:Q7Z314|uniprotkb:Q9NWY7|uniprotkb:B2RN92|ensembl:ENSP00000430338 psi-mi:int5_human(display_long)|uniprotkb:INTS5(gene name)|psi-mi:INTS5(display_short)|uniprotkb:KIAA1698(gene name synonym) psi-mi:int8_human(display_long)|uniprotkb:INTS8(gene name)|psi-mi:INTS8(display_short)|uniprotkb:C8orf52(gene name synonym)|uniprotkb:Protein kaonashi-1(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26617282|imex:IM-28724-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085131.1|ensembl:ENSG00000185085(gene)|ensembl:ENST00000330574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029444|interpro:IPR029445|interpro:IPR040316|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_060334.2|refseq:XP_016869108.1|ensembl:ENSG00000164941(gene)|ensembl:ENST00000523731(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR038751|rcsb pdb:7CUN|reactome:R-HSA-6807505 - function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:2pirjs+e6eyNQayJnDp3NCjUhCk9606 rogid:9fEstP6mNqoKkTZGK70ANCMG7NM9606 rigid:bqjnq+CjCbRlhshfBkXznCDTU64 false his tag:n-n sbp:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617291|imex:IM-28724-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig. 1D, Supp. figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96HW7 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617291|imex:IM-28724-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig. 1D, Supp. figure 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVM9 uniprotkb:Q96SY0 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617300|imex:IM-28724-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:exPdwvnvPy5vfVCiKKhdCwnyFaM false sbp:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVM9 uniprotkb:Q9NVR2 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617300|imex:IM-28724-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rigid:exPdwvnvPy5vfVCiKKhdCwnyFaM false sbp:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P9B9 uniprotkb:Q75QN2 intact:EBI-7600112|intact:MINT-4539005|uniprotkb:Q9C0G5|uniprotkb:Q8N6W5|ensembl:ENSP00000327889 intact:EBI-2340089|uniprotkb:Q5RKZ3|uniprotkb:Q6P1R5|uniprotkb:Q9NVS6|uniprotkb:Q7Z314|uniprotkb:Q9NWY7|uniprotkb:B2RN92|ensembl:ENSP00000430338 psi-mi:int5_human(display_long)|uniprotkb:INTS5(gene name)|psi-mi:INTS5(display_short)|uniprotkb:KIAA1698(gene name synonym) psi-mi:int8_human(display_long)|uniprotkb:INTS8(gene name)|psi-mi:INTS8(display_short)|uniprotkb:C8orf52(gene name synonym)|uniprotkb:Protein kaonashi-1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26617353|imex:IM-28724-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085131.1|ensembl:ENSG00000185085(gene)|ensembl:ENST00000330574(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR029444|interpro:IPR029445|interpro:IPR040316|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_060334.2|refseq:XP_016869108.1|ensembl:ENSG00000164941(gene)|ensembl:ENST00000523731(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR038751|rcsb pdb:7CUN|reactome:R-HSA-6807505 - function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint - figure legend:Fig. 1E. 1F, Supp. Figs. 1B, 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:2pirjs+e6eyNQayJnDp3NCjUhCk9606 rogid:9fEstP6mNqoKkTZGK70ANCMG7NM9606 rigid:bqjnq+CjCbRlhshfBkXznCDTU64 false his tag:n-n sbp:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96HW7 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617361|imex:IM-28724-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig. 1E, 1F, Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617361|imex:IM-28724-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig. 1E, 1F, Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q9NVM9 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26873993|imex:IM-28724-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - - figure legend:Fig. 1E, 1F, Supp. Figs. 1B, 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:exPdwvnvPy5vfVCiKKhdCwnyFaM false his tag:n-n sbp:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q96SY0 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26873993|imex:IM-28724-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - - figure legend:Fig. 1E, 1F, Supp. Figs. 1B, 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:exPdwvnvPy5vfVCiKKhdCwnyFaM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NV88 uniprotkb:Q5TA45 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617408|imex:IM-28724-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 intact:EBI-26617427(see-also) - - figure legend:Fig. 4A|comment:"The Q5TA45:p.[Arg510Pro;Thr512Pro] mutation results in reduced expression of INTS11"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/02/08 2021/02/08 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false ha tag:?-? mutation with no effect:462-462|flag tag:?-?|mutation with complex effect:490-490,482-482|mutation with complex effect:454-455|mutation with complex effect:490-490,492-492|necessary binding region:503-600 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NV88 uniprotkb:Q96HW7 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617408|imex:IM-28724-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 intact:EBI-26617427(see-also) - - figure legend:Fig. 4A|comment:"The Q5TA45:p.[Arg510Pro;Thr512Pro] mutation results in reduced expression of INTS11"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/02/08 2021/02/08 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false ha tag:?-? sbp:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617427|imex:IM-28724-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 intact:EBI-26617408(see-also) - - figure legend:Fig. 4A, Supp. Fig.1H|comment:"The Q5TA45:p.[Arg510Pro;Thr512Pro] mutation results in reduced expression of INTS11."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:CcoRB1cxqYT9okWe7q/CHGH6OYc false mutation with no effect:203-203|flag tag:?-?|sufficient binding region:1-449,503-600|mutation with no effect:480-480,482-482|mutation with no effect:454-455|mutation with no effect:490-490,492-492 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NV88 uniprotkb:Q96HW7 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26874025|imex:IM-28724-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 intact:EBI-26617427(see-also) - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/02/08 2021/03/10 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:Q580Z1YFau+2VXyJsOhaoliX+AM false ha tag:?-? sbp:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617514|imex:IM-28724-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig.4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96HW7 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0030"(cross-linking study) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617514|imex:IM-28724-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Fig.4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/02/08 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96HW7 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0410"(3D electron microscopy) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26619770|wwpdb:7BFP|wwpdb:7BFQ|emdb:EMD-12165|emdb:EMD-12163|emdb:EMD-12164|emdb:EMD-12166|imex:IM-28724-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Table 1, Video S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/11 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26619770|wwpdb:7BFP|wwpdb:7BFQ|emdb:EMD-12165|emdb:EMD-12163|emdb:EMD-12164|emdb:EMD-12166|imex:IM-28724-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Table 1, Video S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2021/02/08 2021/02/11 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:z7UgDcncL6nAqqs1n1kvtAskI1Y false sbp:n-n - - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q5TA45 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617309|imex:IM-28724-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q9NV88 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617309|imex:IM-28724-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q96HW7 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617309|imex:IM-28724-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q96SY0 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617309|imex:IM-28724-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q9NVM9 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617309|imex:IM-28724-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617323|imex:IM-28724-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96HW7 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617323|imex:IM-28724-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q96SY0 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617323|imex:IM-28724-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NVM9 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617323|imex:IM-28724-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false maltose binding protein tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5TA45 uniprotkb:Q9NVR2 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:"MI:0096"(pull down) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617323|imex:IM-28724-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false maltose binding protein tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q5TA45 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617384|imex:IM-28724-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n sbp:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q9NVM9 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617384|imex:IM-28724-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - - figure legend:Supp. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n sbp:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q96SY0 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617384|imex:IM-28724-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - - figure legend:Supp. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q96HW7 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617384|imex:IM-28724-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NVR2 uniprotkb:Q9NV88 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pfleiderer et al. (2021) pubmed:33548203|imex:IM-28724 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26617384|imex:IM-28724-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Supp. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/02/08 2021/03/10 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:EIEmH1r0gxniJARWvrgae8rCdvM false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)|psi-mi:"MI:0396"(predetermined participant)