#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01995 uniprotkb:Q9UQ80 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9UIV1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q7Z434 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P35249 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P35244 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6IPH7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-7813901|intact:MINT-4999879 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6iph7_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR039660|interpro:IPR041985|mint:Q6IPH7 - - comment:mint figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:5CcL53ast8OqaEim7RismPJTO0Y9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5VXV3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-8456402|intact:UNK-5457610 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5vxv3_human(display_long)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)|uniprotkb:hCG_40357(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001116293.1|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|go:"GO:0005654"(nucleoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0006334"(nucleosome assembly) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8N5N7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-7825175|uniprotkb:B7Z358|ensembl:ENSP00000363999|uniprotkb:Q9NX15|intact:UNK-5522445|uniprotkb:Q5T7E0 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rm50_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL50(gene name synonym)|uniprotkb:MRPL50(gene name)|psi-mi:MRPL50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000136897(gene)|ensembl:ENST00000374865(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR018305|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0|refseq:NP_061924.1 - - comment:mint figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Qo0MGo2Bv7DnWEFNu0IPOnGXoWE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y5B6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2557602|uniprotkb:Q9NYQ0|uniprotkb:Q96DU8|uniprotkb:D3DSE7|ensembl:ENSP00000328992|ensembl:ENSP00000458262|ensembl:ENSP00000458892 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:paxb1_human(display_long)|uniprotkb:PAXBP1(gene name)|psi-mi:PAXBP1(display_short)|uniprotkb:C21orf66(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 1(gene name synonym)|uniprotkb:GCFC(gene name synonym)|uniprotkb:GCFC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_037461.2|refseq:NP_057715.2|ensembl:ENSG00000159086(gene)|ensembl:ENSG00000263141(gene)|ensembl:ENST00000331923(transcript)|ensembl:ENST00000573680(transcript)|ensembl:ENST00000574159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000288"(positive regulation of myoblast proliferation)|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|interpro:IPR022783 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:SYrCt+PvgtLbYgHiN2ZP7yPEnIk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y3Z3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y3U8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y3B4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y2W2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y2S6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-6269510|ensembl:ENSP00000397843|uniprotkb:Q9P052 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tma7_human(display_long)|uniprotkb:TMA7(gene name)|psi-mi:TMA7(display_short)|uniprotkb:CCDC72(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 72(gene name synonym)|uniprotkb:HSPC016(orf name)|uniprotkb:HSPC330(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR015157(Translation machinery associated TMA7)|ensembl:ENSG00000232112(gene)|ensembl:ENST00000438607(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_057017.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Lwy203R7sJAt/S3tOTGPIeqS5KI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9UI30 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9UBW8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-712982|ensembl:ENSP00000229251|ensembl:ENSP00000438115|ensembl:ENSP00000438363|ensembl:ENSP00000441852|ensembl:ENSP00000446039|uniprotkb:Q9NVX3|uniprotkb:Q9UJW4|uniprotkb:A8K9A6 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:csn7a_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 7a(gene name synonym)|uniprotkb:Dermal papilla-derived protein 10(gene name synonym)|uniprotkb:COPS7A(gene name)|psi-mi:COPS7A(display_short)|uniprotkb:CSN7A(gene name synonym)|uniprotkb:DERP10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000111652(gene)|ensembl:ENST00000229251(transcript)|ensembl:ENST00000534877(transcript)|ensembl:ENST00000534947(transcript)|ensembl:ENST00000539735(transcript)|ensembl:ENST00000543155(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0010387"(COP9 signalosome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR037757|interpro:IPR041481|mint:Q9UBW8|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:NP_001157565.1|refseq:NP_001157566.1|refseq:NP_001157567.1|refseq:NP_057403.1|refseq:XP_005253751.1|dip:DIP-53412N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:KT1zw5OuZthyscvNa/4lW1iJz2Q9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9P016 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2795681|uniprotkb:Q567Q2|uniprotkb:Q9H3L4|uniprotkb:Q9HC20|ensembl:ENSP00000341657|ensembl:ENSP00000376373|ensembl:ENSP00000376374 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:thyn1_human(display_long)|uniprotkb:THYN1(gene name)|psi-mi:THYN1(display_short)|uniprotkb:THY28(gene name synonym)|uniprotkb:Thymocyte protein Thy28(gene name synonym)|uniprotkb:HSPC144(orf name)|uniprotkb:MDS012(orf name)|uniprotkb:My0054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001032381.1|refseq:NP_001032382.1|refseq:NP_054893.1|refseq:NP_954994.1|refseq:NP_954995.1|mint:Q9P016|rcsb pdb:3EOP|rcsb pdb:5J3E|interpro:IPR015947(PUA-like)|ensembl:ENSG00000151500(gene)|ensembl:ENST00000341541(transcript)|ensembl:ENST00000392594(transcript)|ensembl:ENST00000392595(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR002740(Protein of unknown function DUF55) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:a/mbijtJl0FzO3ZmXwBTXp0uTyU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9HDC9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9H5Z5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880154 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q9h5z5_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0007018"(microtubule-based movement)|go:"GO:1990939"|interpro:IPR027640 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:599JZdiyKAcBU6iaSSz1mAoN34A9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9H000 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BVV7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-6570759|uniprotkb:Q9P010|ensembl:ENSP00000169551 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tim21_human(display_long)|uniprotkb:TIMM21(gene name)|psi-mi:TIMM21(display_short)|uniprotkb:TIM21-like protein, mitochondrial(gene name synonym)|uniprotkb:HSPC154(orf name)|uniprotkb:C18orf55(gene name synonym)|uniprotkb:TIM21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000075336(gene)|ensembl:ENST00000169551(transcript)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR013261(Mitochondrial import inner membrane translocase, subunit Tim21)|interpro:IPR038552|reactome:R-HSA-1268020|refseq:NP_054896.2 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/iiwo2Ow/n6nP6pWgf/QI/V8CNg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BVC5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-5458641|uniprotkb:B3KXN3|ensembl:ENSP00000258457|uniprotkb:B4E2G9 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:ashwn_human(display_long)|uniprotkb:C2orf49(gene name)|psi-mi:C2orf49(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_076998.1|ensembl:ENSG00000135974(gene)|ensembl:ENST00000258457(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR024887|reactome:R-HSA-6784531|refseq:NP_001273466.1|refseq:XP_016860381.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:G3jad0mGv7VlRQWj5kloN+mO+X49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BV28 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880135 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q9bv28_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|interpro:IPR002453(Beta tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR037103|interpro:IPR036525|interpro:IPR023123|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:FVTwBFsEbDz0dPNmyc2XBxOzwH89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BU61 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BQQ5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-25605288 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q9bqq5_human(display_long)|uniprotkb:L27a(gene name)|psi-mi:L27a(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005840"(ribosome)|interpro:IPR027386|interpro:IPR036227|interpro:IPR021131 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Pwh5uF7oDoeeJ+YBja/4Ms9v7XM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q99988 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q99714 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q96SI9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-740355|uniprotkb:Q32NB9|uniprotkb:Q9BUE1|uniprotkb:Q9BXG4|uniprotkb:Q9H0B4|uniprotkb:Q9H7V1|uniprotkb:Q9NUK4|ensembl:ENSP00000321347|ensembl:ENSP00000415968 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:strbp_human(display_long)|uniprotkb:STRBP(gene name)|psi-mi:STRBP(display_short)|uniprotkb:SPNR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001164608.1|refseq:NP_060857.2|ensembl:ENSG00000165209(gene)|ensembl:ENST00000348403(transcript)|ensembl:ENST00000447404(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008017"(microtubule binding)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR030446|interpro:IPR043519|interpro:IPR044472|rcsb pdb:2DMY|refseq:XP_016870383.1|refseq:XP_016870384.1|refseq:XP_016870385.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:xVEZqCqBcH0MBB1Ar9SU+9Yhsbs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q96RS2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2696165 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q96rs2_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR001865(Ribosomal protein S2)|interpro:IPR018130|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR023591|interpro:IPR032281|interpro:IPR027498|interpro:IPR027504|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043236"(laminin binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:MVL01+hZq1ml5ukIglcHL9SW20k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q96EP5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2133162|uniprotkb:Q96MJ3|uniprotkb:Q9NRR9|ensembl:ENSP00000233078 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dazp1_human(display_long)|uniprotkb:DAZAP1(gene name)|psi-mi:DAZAP1(display_short)|uniprotkb:Deleted in azoospermia-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_061832.2|refseq:NP_733829.1|ensembl:ENSG00000071626(gene)|ensembl:ENST00000233078(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034131|interpro:IPR034134|interpro:IPR035979|mint:Q96EP5|rcsb pdb:2DGS|rcsb pdb:2DH8 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:4uZCZTXZGnZAD9tBcurmc8RhGwY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q96E39 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2211204|ensembl:ENSP00000318415|ensembl:ENSP00000446099|ensembl:ENSP00000498248 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rmxl1_human(display_long)|uniprotkb:RBMXL1(gene name)|psi-mi:RBMXL1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001156008.1|refseq:NP_062556.2|ensembl:ENSG00000213516(gene)|ensembl:ENST00000321792(transcript)|ensembl:ENST00000399794(transcript)|ensembl:ENST00000652648(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:J2BrUHGcladV+yTecfJVfljlFz89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P31483 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_071320.2|refseq:NP_071505.2|ensembl:ENSG00000116001(gene)|ensembl:ENST00000433529(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034830|interpro:IPR034832|interpro:IPR035979|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|reactome:R-HSA-6803529|mint:P31483 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q92997 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q92973 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q92665 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q92552 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8WY22 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8WWC4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8WVW9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880126 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q8wvw9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:JkgL+MC1Kw7Vd/jDutObVh25MF09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8TE73 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1057712|uniprotkb:Q92860|uniprotkb:Q96L74|uniprotkb:Q9H5S7|uniprotkb:Q9HCG9|ensembl:ENSP00000265104 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dyh5_human(display_long)|uniprotkb:DNAH5(gene name)|psi-mi:DNAH5(display_short)|uniprotkb:DNAHC5(gene name synonym)|uniprotkb:KIAA1603(gene name synonym)|uniprotkb:HL1(gene name synonym)|uniprotkb:Axonemal beta dynein heavy chain 5(gene name synonym)|uniprotkb:Ciliary dynein heavy chain 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001360.1|ensembl:ENSG00000039139(gene)|ensembl:ENST00000265104(transcript)|go:"GO:0003341"(cilium movement)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030286"(dynein complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0036157"(outer dynein arm)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0060271"(cilium assembly)|go:"GO:0097729"(9+2 motile cilium)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026983|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041589|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|mint:Q8TE73|go:"GO:0051959"(dynein light intermediate chain binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ZJjSo4ExUpYJLO/y8HNgZdnndFo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8TCS8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1052020|uniprotkb:Q53SU0|uniprotkb:Q68CN1|uniprotkb:Q7Z7D1|uniprotkb:Q8IWX1|uniprotkb:Q96T05|uniprotkb:Q9BRU3|uniprotkb:Q9BVX0|ensembl:ENSP00000393953|ensembl:ENSP00000400646 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:pnpt1_human(display_long)|uniprotkb:Polynucleotide phosphorylase 1(gene name synonym)|uniprotkb:Polynucleotide phosphorylase-like protein(gene name synonym)|uniprotkb:PNPase old-35(gene name synonym)|uniprotkb:3'-5' RNA exonuclease OLD35(gene name synonym)|uniprotkb:PNPT1(gene name)|psi-mi:PNPT1(display_short)|uniprotkb:PNPASE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_149100.2|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0097222"(mitochondrial mRNA polyadenylation)|go:"GO:0097421"(liver regeneration)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR003029(S1, RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR020568|interpro:IPR022967|interpro:IPR027408|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|rcsb pdb:3U1K|rcsb pdb:5ZF6|ensembl:ENSG00000138035(gene)|ensembl:ENST00000415374(transcript)|ensembl:ENST00000447944(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000957"(mitochondrial RNA catabolic process)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0034046"("poly(G) binding")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035927"(RNA import into mitochondrion)|go:"GO:0035928"(rRNA import into mitochondrion)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0004654"(polyribonucleotide nucleotidyltransferase activity)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060416"(response to growth hormone)|dip:DIP-50226N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:W9hr1vfWv1b0v4xfMYatfKfOMcg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8N183 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2682365|uniprotkb:A8K5I1|ensembl:ENSP00000296597 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:nduf2_human(display_long)|uniprotkb:NDUFA12L(gene name synonym)|uniprotkb:B17.2-like(gene name synonym)|uniprotkb:Myc-induced mitochondrial protein(gene name synonym)|uniprotkb:NDUFA12-like protein(gene name synonym)|uniprotkb:NDUFAF2(gene name)|psi-mi:NDUFAF2(display_short)|uniprotkb:Mimitin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_777549.1|ensembl:ENSG00000164182(gene)|ensembl:ENST00000296597(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|reactome:R-HSA-6799198 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:sNje5xhXA48xAg0tSkOYiqBxZvk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8N0T1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-9246542|uniprotkb:B2RXE7|uniprotkb:E5RFW5|ensembl:ENSP00000481745|ensembl:ENSP00000482944|ensembl:ENSP00000484101|ensembl:ENSP00000484492|ensembl:ENSP00000484811 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rbis_human(display_long)|uniprotkb:C8orf59(gene name synonym)|uniprotkb:RBIS(gene name)|psi-mi:RBIS(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001093140.1|refseq:NP_001093141.1|refseq:NP_001093142.1|refseq:NP_001093143.1|refseq:XP_011515830.1|ensembl:ENSG00000176731(gene)|ensembl:ENST00000611854(transcript)|ensembl:ENST00000612809(transcript)|ensembl:ENST00000612977(transcript)|ensembl:ENST00000615697(transcript)|ensembl:ENST00000619594(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR031389 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:9ddaysgPc7rXLRG8E0LSgapMv7Y9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P31040 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q86WV4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880115 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q86wv4_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:TsodjTxHUuzDKAIStuBwxsJt3go9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q7Z759 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-11602463 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q7z759_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:T-complex protein 1 subunit theta(gene name synonym)|uniprotkb:hCG_1810843(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001269837.1|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:aBKNyERuRMi13krz6sEqk7TZQos9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q71UM5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q71U36 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6ZVX0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880104 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6zvx0_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0016020"(membrane)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:DxIpZXCujkrJR+Z8LgKYdRYoLKI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6ZQN2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880100 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6zqn2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 - - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:U3wUceAdgTy4gWb9ItM3pjobOWM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6P1J9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6IPX4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-4404679|ensembl:ENSP00000367806 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6ipx4_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:XP_005259194.1|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|ensembl:ENST00000339471(transcript)|ensembl:ENSG00000105193(gene) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:AKPmtNIcQnb9QTqof/UvzgytaZE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6FIA3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880078 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6fia3_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070836"(caveola assembly)|go:"GO:0097320"(plasma membrane tubulation)|refseq:NP_001171900.1|refseq:XP_005261376.1|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR035743|interpro:IPR028521|interpro:IPR037453|interpro:IPR036028|interpro:IPR001452(Src homology-3) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:2D/V1dekijESrOkpQ79iAE15Ozk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6FG99 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-20625321 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q6fg99_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006414"(translational elongation)|interpro:IPR038716|interpro:IPR027534 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:4oHWoH/AO/3eEIzPfifs3kEFMdw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q6DKK2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-948354|ensembl:ENSP00000261647|uniprotkb:Q7L3U8|uniprotkb:Q9NXB2|uniprotkb:A8MZ52|uniprotkb:B3KP62|uniprotkb:B4DN65|uniprotkb:Q9H6G3|uniprotkb:Q2M248 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:ttc19_human(display_long)|uniprotkb:TTC19(gene name)|psi-mi:TTC19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000011295(gene)|ensembl:ENST00000261647(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0070469"(respirasome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040395|mint:Q6DKK2|refseq:NP_001258349.1|refseq:NP_060245.3 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:skTQJ+iUoHBb06IqVhoprLMYEtA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q69YZ2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-20595042|uniprotkb:Q6P2G8|uniprotkb:Q6P2Q5|ensembl:ENSP00000428459|ensembl:ENSP00000428544 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:t200b_human(display_long)|uniprotkb:Transmembrane protein TTMA(gene name synonym)|uniprotkb:Two transmembrane domain-containing family member B(gene name synonym)|uniprotkb:TMEM200B(gene name)|psi-mi:TMEM200B(display_short)|uniprotkb:TTMB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001003682.1|refseq:NP_001165339.1|ensembl:ENSG00000253304(gene)|ensembl:ENST00000420504(transcript)|ensembl:ENST00000521452(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018787 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:nuAiZWBDNQuUiod2wJdk0o2dVEs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q68CT4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880062 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q68ct4_human(display_long)|uniprotkb:DKFZp686A1668(gene name)|psi-mi:DKFZp686A1668(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR017868|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR029874|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR044801 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:8MBr3EN1ztQvzlxvM1TH2fNW95c9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5XPV6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880054 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5xpv6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR017131(Small ribonucleoprotein associated, SmB/SmN) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:C/kOK/n01k30I022dMCWs07iWCI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5U0D2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880039 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5u0d2_human(display_long)|uniprotkb:DKFZp686P11128(gene name)|psi-mi:DKFZp686P11128(display_short)|uniprotkb:TAGLN(gene name synonym)|uniprotkb:hCG_2032895(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0051015"(actin filament binding)|refseq:NP_001001522.1|refseq:NP_003177.2|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR003096(SM22/calponin)|interpro:IPR029976 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5U0C2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880031 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5u0c2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003677"(DNA binding)|go:"GO:0006260"(DNA replication)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:65aDSseuniznA44O9baNj5irhyI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5T8U2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880014|ensembl:ENSP00000361071 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5t8u2_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:RP11-244N20.10-005(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000148303(gene)|ensembl:ENST00000315731(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:EybpTPK1PiyrU/1O9f5SZeY6Zhw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5T765 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26880000 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5t765_human(display_long)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:hCG_24570(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0035457"(cellular response to interferon-alpha)|refseq:NP_001026853.1|refseq:NP_001540.2|interpro:IPR024122|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5SWC8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879981|ensembl:ENSP00000402754 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5swc8_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000127483(gene)|ensembl:ENST00000424732(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/em7stWF0BnGkfIW/4tOApKGF+o9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5RZA0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879975 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5rza0_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036188|interpro:IPR023753 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/dv0RNMLh8TkY+Hgf/T4UsQP9eE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5RKV6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5JPE7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2680477|ensembl:ENSP00000370883|ensembl:ENSP00000477502|intact:EBI-3957033|uniprotkb:Q4G177 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:nomo2_human(display_long)|uniprotkb:pM5 protein 2(gene name synonym)|uniprotkb:NOMO2(gene name)|psi-mi:NOMO2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001004060.1|refseq:NP_775885.1|ensembl:ENSG00000185164(gene)|ensembl:ENST00000381474(transcript)|ensembl:ENST00000621364(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Nqg3PkM8MmXjl/n314IAbUrY4C89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q5HYG8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879960 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q5hyg8_human(display_long)|uniprotkb:DKFZp686P09201(gene name)|psi-mi:DKFZp686P09201(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|refseq:NP_001159830.1|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|interpro:IPR039429 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:LpX2TAslcsdAmzqUjydmYtBcQ1o9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q16718 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q59GY0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879952 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q59gy0_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:t7w+xbT4c0FGRnmV2ISr0YbKE8k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q59GV2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879945 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q59gv2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003676"(nucleic acid binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:O2bSFJByB0xDEBSOzICFEKEnFP09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q59FU3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879935 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q59fu3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:mWQa5KC3KEPeOzJiL5iS9ftu01Y9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53ZP9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879925 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53zp9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005524"(ATP binding)|interpro:IPR043129|interpro:IPR018181|interpro:IPR029048|interpro:IPR029047|interpro:IPR013126(Heat shock protein 70)|interpro:IPR042708 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Rj0HuI2eQd83Fw9XsAbJS/L4/AY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53T70 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879916 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53t70_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:91H+e9qzFLJeDI7QRMnZWHueaz89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53R94 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879912 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53r94_human(display_long)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 - - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:oBIzQxRCFzBo0nYgHuelOJRg3Ec9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53HH4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879898 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53hh4_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045087"(innate immune response)|interpro:IPR034375|interpro:IPR034374|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR032710|interpro:IPR018222|interpro:IPR039539|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:mrUr44U/edOJ383eLh+jDNmbtAQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53HE2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26662549 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53he2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|refseq:NP_000356.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR035990|interpro:IPR022896|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR020861 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:PXiDrCsU/m6J0WoRnjzFHKQrI3c9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53GC9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879890 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53gc9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0051015"(actin filament binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR003096(SM22/calponin)|interpro:IPR029976 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CAj04IG9QKn5Fe+mw/2d2bo0scU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53G58 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879876 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53g58_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR027333|interpro:IPR015505(Coronin)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CmI+jOeLYuEYUJVRZxSJZNKdBM09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53FV3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879865 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53fv3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR037754|interpro:IPR041406|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR040134|interpro:IPR036388|interpro:IPR036390 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pW5rSfHsj7esfkEHxcrTxx2z0KY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53FM7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879856 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53fm7_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR037232|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR020396 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:fCNCIgmo8oE2b7DH5V7EzExQQXQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q53FF5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879847 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q53ff5_human(display_long)|uniprotkb:p97 cofactor p47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005795"(Golgi stack)|interpro:IPR036241|interpro:IPR012989(SEP)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR001012(UBX) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+EKNINcVo/4sanTJ0g4/VaII5/k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P43487 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q4QZC0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879834 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q4qzc0_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR037055|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:s5Oj2TGgPQkae7I+fBZXHRARCQQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P62633 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q3YEC7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-742029|uniprotkb:A8QVZ7|uniprotkb:Q4F968|uniprotkb:Q5T5R7|uniprotkb:Q8IWK1|uniprotkb:Q8TCL4|uniprotkb:Q8WU94|uniprotkb:Q96SR8|uniprotkb:Q9BU21|uniprotkb:Q9H935|uniprotkb:A8QVZ8|uniprotkb:C6K8I4|uniprotkb:C6K8I5|ensembl:ENSP00000311134 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rabl6_human(display_long)|uniprotkb:RABL6(gene name)|psi-mi:RABL6(display_short)|uniprotkb:C9orf86(gene name synonym)|uniprotkb:GTP-binding protein Parf(gene name synonym)|uniprotkb:PARF(gene name synonym)|uniprotkb:Partner of ARF(gene name synonym)|uniprotkb:Rab-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001167459.1|refseq:NP_078994.3|refseq:NP_001167460.1|ensembl:ENSG00000196642(gene)|ensembl:ENST00000311502(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|interpro:IPR027417|interpro:IPR040385|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:AZhkTh4+32Qxv5/Dy4ebg+mv3Ls9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q2VIR3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-6152253|uniprotkb:F8W810|uniprotkb:Q5I0X0|uniprotkb:Q6KF84|ensembl:ENSP00000445077 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:if2gl_human(display_long)|uniprotkb:EIF2S3B(gene name)|psi-mi:EIF2S3B(display_short)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000180574(gene)|ensembl:ENST00000538173(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:PWCg1+Txl6XGdC4iHan7A9SGDwg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q16186 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q15515 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2556910 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q15515_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0001533"(cornified envelope)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0009411"(response to UV)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051258"(protein polymerization)|interpro:IPR029142 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0ee6NxMqQFbNL5DURPz46bZ+i149606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q15046 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q14254 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-348613|ensembl:ENSP00000378368 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004466.2|ensembl:ENSG00000132589(gene)|go:"GO:0008544"(epidermis development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|ensembl:ENST00000394908(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q14162 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-12056025|ensembl:ENSP00000263071|ensembl:ENSP00000481595|uniprotkb:A8MQ05|uniprotkb:O43701|uniprotkb:Q8NHD2|uniprotkb:Q8NHD3|uniprotkb:Q8NHD4|uniprotkb:Q8NHD5 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:srec_human(display_long)|uniprotkb:SCARF1(gene name)|psi-mi:SCARF1(display_short)|uniprotkb:Acetyl LDL receptor(gene name synonym)|uniprotkb:KIAA0149(gene name synonym)|uniprotkb:SREC(gene name synonym)|uniprotkb:Scavenger receptor expressed by endothelial cells 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000074660(gene)|ensembl:ENSG00000276336(gene)|ensembl:ENST00000263071(transcript)|ensembl:ENST00000621348(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016358"(dendrite development)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0048680"(positive regulation of axon regeneration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR033329|interpro:IPR042635|reactome:R-HSA-3000484|refseq:NP_003684.2|refseq:NP_663325.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OsBdxJKWJjPZMF0uadG8GnmgJOE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q13813 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q13616 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q13601 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q13561 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:JrL5jUtArek+zqmCkPKomnjuSf09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q12874 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q0D2M2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-25624536 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q0d2m2_human(display_long)|uniprotkb:HIST1H2BC(gene name)|psi-mi:HIST1H2BC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:UmhGgG3xZvhCraO/zArXsF678h89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q05BX4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879820 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:q05bx4_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000502"(proteasome complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR035266|interpro:IPR040623 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:y2YXKFSj+1jXBRYM3xt5/WODoE49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q02790 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002005.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6RCY|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|ensembl:ENST00000001008(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|ensembl:ENSG00000004478(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0006825"(copper ion transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0032767"(copper-dependent protein binding)|dip:DIP-50866N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P82979 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-347495|uniprotkb:Q9P066|uniprotkb:A8K393|ensembl:ENSP00000337632|ensembl:ENSP00000449409 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:sarnp_human(display_long)|uniprotkb:HSPC316(orf name)|uniprotkb:Cytokine-induced protein of 29 kDa(gene name synonym)|uniprotkb:SARNP(gene name)|psi-mi:SARNP(display_short)|uniprotkb:Proliferation-associated cytokine-inducible protein CIP29(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:Nuclear protein Hcc-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_149073.1|ensembl:ENSG00000205323(gene)|ensembl:ENST00000336133(transcript)|ensembl:ENST00000546604(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR036361|mint:P82979|rcsb pdb:2DO1|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR003034(DNA-binding SAP) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:O/j7XYd9K3eQu1JS58FSsEyPRpE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P63208 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P62891 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P62877 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P61106 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_057406.2|ensembl:ENSG00000119396(gene)|ensembl:ENST00000373840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P54920 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P54578 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1048016|uniprotkb:Q53XY5|uniprotkb:B7Z4N8|uniprotkb:J3QRZ5|ensembl:ENSP00000261601 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:ubp14_human(display_long)|uniprotkb:USP14(gene name)|psi-mi:USP14(display_short)|uniprotkb:TGT(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 14(gene name synonym)|uniprotkb:Deubiquitinating enzyme 14(gene name synonym)|uniprotkb:Ubiquitin thioesterase 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001032411.1|refseq:NP_005142.1|ensembl:ENSG00000101557(gene)|ensembl:ENST00000261601(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0045087"(innate immune response)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR019954|interpro:IPR028889|interpro:IPR029071|interpro:IPR038765|interpro:IPR044635|mint:P54578|rcsb pdb:2AYN|rcsb pdb:2AYO|rcsb pdb:5GJQ|rcsb pdb:6IIK|rcsb pdb:6IIL|rcsb pdb:6IIM|rcsb pdb:6IIN|rcsb pdb:6LVS|reactome:R-HSA-5689880|go:"GO:0070628"(proteasome binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:5hXfHmHds5nuvdlFYWoB/G6nvmk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P54577 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1048893|uniprotkb:O43276|uniprotkb:Q53EN1|uniprotkb:B3KWK4|uniprotkb:D3DPQ4|ensembl:ENSP00000362576 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:syyc_human(display_long)|uniprotkb:YARS1(gene name)|psi-mi:YARS1(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:YARS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_003671.1|ensembl:ENSG00000134684(gene)|ensembl:ENST00000373477(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005153"(interleukin-8 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006437"(tyrosyl-tRNA aminoacylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:1N3L|rcsb pdb:1NTG|rcsb pdb:1Q11|rcsb pdb:4Q93|rcsb pdb:4QBT|rcsb pdb:5THH|rcsb pdb:5THL|reactome:R-HSA-379716|dip:DIP-50415N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:y/0Qs8iOgW5w5LVLWnCvowVpEu89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P53618 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P53396 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P51858 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-3910118|uniprotkb:Q5SZ09|uniprotkb:D3DVC9|uniprotkb:Q5SZ07|uniprotkb:B3KU21|uniprotkb:Q5SZ08|ensembl:ENSP00000349878|ensembl:ENSP00000443120 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:hdgf_human(display_long)|uniprotkb:HDGF(gene name)|psi-mi:HDGF(display_short)|uniprotkb:HMG1L2(gene name synonym)|uniprotkb:High mobility group protein 1-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001119522.1|refseq:NP_001119523.1|refseq:NP_004485.1|refseq:NP_001306115.1|refseq:NP_001306116.1|refseq:NP_001306117.1|ensembl:ENSG00000143321(gene)|ensembl:ENST00000357325(transcript)|ensembl:ENST00000537739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000313(PWWP)|interpro:IPR035496|mint:P51858|rcsb pdb:1RI0|rcsb pdb:2NLU|reactome:R-HSA-381038 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:72uY+spcb4la5tJDUhHHtOn/Zrs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P51610 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P50750 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P50395 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P48735 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P47813 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1045377|uniprotkb:Q0VGC2|uniprotkb:Q5JPS5|uniprotkb:Q5JPS6|uniprotkb:B2R5U5|ensembl:ENSP00000368927 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:if1ax_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:EIF1AX(gene name)|psi-mi:EIF1AX(display_short)|uniprotkb:EIF1A(gene name synonym)|uniprotkb:EIF4C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001403.1|ensembl:ENSG00000173674(gene)|ensembl:ENST00000379607(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104|rcsb pdb:1D7Q|rcsb pdb:3ZJY|rcsb pdb:4KZY|rcsb pdb:4KZZ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016855198.1|dip:DIP-40995N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:C/YFiphF76YhqKYoM7ybw320ihw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P35754 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-3905236|uniprotkb:Q3KQS1|uniprotkb:B2R4L2|uniprotkb:Q6ICT1|ensembl:ENSP00000237858|ensembl:ENSP00000369314|ensembl:ENSP00000422708|ensembl:ENSP00000424636|ensembl:ENSP00000427353 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:glrx1_human(display_long)|uniprotkb:GLRX(gene name)|psi-mi:GLRX(display_short)|uniprotkb:GRX(gene name synonym)|uniprotkb:Thioltransferase-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001112362.1|refseq:NP_001230587.1|refseq:NP_001230588.1|refseq:NP_002055.1|ensembl:ENSG00000173221(gene)|ensembl:ENST00000237858(transcript)|ensembl:ENST00000379979(transcript)|ensembl:ENST00000505427(transcript)|ensembl:ENST00000508780(transcript)|ensembl:ENST00000512469(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0015038"(glutathione disulfide oxidoreductase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080058"(protein deglutathionylation)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:1B4Q|rcsb pdb:1JHB|rcsb pdb:4RQR|reactome:R-HSA-499943 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:TuN1okhO+Dk2jJYF8F8l4I9jqZQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P33316 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P30049 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1049505|uniprotkb:Q6FG90|uniprotkb:D6W5Y3|ensembl:ENSP00000215375|ensembl:ENSP00000378995|ensembl:ENSP00000464863 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:atpd_human(display_long)|uniprotkb:ATP5F1D(gene name)|psi-mi:ATP5F1D(display_short)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:ATP5D(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001001975.1|refseq:NP_001678.1|ensembl:ENSG00000099624(gene)|ensembl:ENST00000215375(transcript)|ensembl:ENST00000395633(transcript)|ensembl:ENST00000591660(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046688"(response to copper ion)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|interpro:IPR036794|mint:P30049|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OA8if7wpjwV6hkkaLqPyz6YDljc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P29084 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2853321|uniprotkb:Q9H2B9|uniprotkb:D3DSV2|ensembl:ENSP00000348168 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:t2eb_human(display_long)|uniprotkb:GTF2E2(gene name)|psi-mi:GTF2E2(display_short)|uniprotkb:TF2E2(gene name synonym)|uniprotkb:General transcription factor IIE subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002086.1|refseq:XP_016868852.1|refseq:XP_016868853.1|dip:DIP-716N|ensembl:ENSG00000197265(gene)|ensembl:ENST00000355904(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR003166(Transcription factor TFIIE beta subunit, core)|interpro:IPR016656(Transcription initiation factor IIE, beta subunit)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040501|mint:P29084|rcsb pdb:1D8J|rcsb pdb:1D8K|rcsb pdb:5GPY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:lTDT136qMQVOQf83W7wug9v9hw09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P27144 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-3905025|uniprotkb:B2R927|uniprotkb:Q8IUU9|uniprotkb:Q6NXQ5|uniprotkb:Q6IBH4|uniprotkb:D3DQ62|ensembl:ENSP00000322175|ensembl:ENSP00000378743|ensembl:ENSP00000445912 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:kad4_human(display_long)|uniprotkb:AK4(gene name)|psi-mi:AK4(display_short)|uniprotkb:AK3(gene name synonym)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:Adenylate kinase 3-like(gene name synonym)|uniprotkb:"GTP:AMP phosphotransferase AK4"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001005353.1|refseq:NP_037542.1|refseq:NP_982289.1|ensembl:ENSG00000162433(gene)|ensembl:ENST00000327299(transcript)|ensembl:ENST00000395334(transcript)|ensembl:ENST00000545314(transcript)|go:"GO:0001889"(liver development)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0042493"|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001169"(regulation of ATP biosynthetic process)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028585|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|rcsb pdb:2AR7|rcsb pdb:2BBW|rcsb pdb:3NDP|reactome:R-HSA-499943|go:"GO:0006172"(ADP biosynthetic process) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Yt5oLpkD4mw2eCmEbLox3W3R2hw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P22528 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P14649 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P13796 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-698036|uniprotkb:Q5TBN4|uniprotkb:B2R613|uniprotkb:B4DUA0|ensembl:ENSP00000315757|ensembl:ENSP00000381581 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:plsl_human(display_long)|uniprotkb:L-plastin(gene name synonym)|uniprotkb:Lymphocyte cytosolic protein 1(gene name synonym)|uniprotkb:LC64P(gene name synonym)|uniprotkb:LCP1(gene name)|psi-mi:LCP1(display_short)|uniprotkb:PLS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002289.2|refseq:XP_005266431.1|dip:DIP-34767N|ensembl:ENSG00000136167(gene)|ensembl:ENST00000323076(transcript)|ensembl:ENST00000398576(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002102"(podosome)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|rcsb pdb:2D85|rcsb pdb:5JOJ|rcsb pdb:5JOL|reactome:R-HSA-8950505 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:1uy1zhroB3GHUiAwLjEdP5Rz1xM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P13473 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P12273 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P09914 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-745117|uniprotkb:Q96QM5|intact:EBI-11024988|uniprotkb:B3KS50|uniprotkb:D3DR31|ensembl:ENSP00000360869|uniprotkb:Q5T7J1 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:ifit1_human(display_long)|uniprotkb:Interferon-induced 56 kDa protein(gene name synonym)|uniprotkb:IFIT1(gene name)|psi-mi:IFIT1(display_short)|uniprotkb:G10P1(gene name synonym)|uniprotkb:IFI56(gene name synonym)|uniprotkb:IFNAI1(gene name synonym)|uniprotkb:ISG56(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001539.3|refseq:NP_001257857.1|refseq:NP_001257858.1|refseq:NP_001257859.1|ensembl:ENSG00000185745(gene)|ensembl:ENST00000371804(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009615"(response to virus)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043657"(host cell)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0071357"(cellular response to type I interferon)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024121|mint:P09914|rcsb pdb:4HOU|rcsb pdb:5UDI|rcsb pdb:5UDJ|rcsb pdb:5UDK|rcsb pdb:5UDL|rcsb pdb:5W5H|rcsb pdb:5W5I|rcsb pdb:6C6K|reactome:R-HSA-1169408|reactome:R-HSA-909733|dip:DIP-37898N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ANeil+D2pneKAoDFS4Vy97BHu8A9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P07814 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P06737 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2511865|ensembl:ENSP00000216392|uniprotkb:O60567|uniprotkb:O60913|uniprotkb:O60752|uniprotkb:A6NDQ4|uniprotkb:Q501V9|uniprotkb:Q96G82|uniprotkb:Q641R5|uniprotkb:B4DUB7|uniprotkb:F5H816 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:pygl_human(display_long)|uniprotkb:PYGL(gene name)|psi-mi:PYGL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100504(gene)|ensembl:ENST00000216392(transcript)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0019842"(vitamin binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:P06737|rcsb pdb:1EM6|rcsb pdb:1EXV|rcsb pdb:1FA9|rcsb pdb:1FC0|rcsb pdb:1L5Q|rcsb pdb:1L5R|rcsb pdb:1L5S|rcsb pdb:1L7X|rcsb pdb:1XOI|rcsb pdb:2ATI|rcsb pdb:2QLL|rcsb pdb:2ZB2|rcsb pdb:3CEH|rcsb pdb:3CEJ|rcsb pdb:3CEM|rcsb pdb:3DD1|rcsb pdb:3DDS|rcsb pdb:3DDW|reactome:R-HSA-70221|reactome:R-HSA-6798695|refseq:NP_001157412.1|refseq:NP_002854.3 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:8h3TR7UB7SC/CFh5TXcjHvE/C709606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P05161 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-746466|uniprotkb:Q7Z2G2|uniprotkb:Q96GF0|intact:EBI-1056284|uniprotkb:Q5SVA4|ensembl:ENSP00000496832 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:isg15_human(display_long)|uniprotkb:ISG15(gene name)|psi-mi:ISG15(display_short)|uniprotkb:G1P2(gene name synonym)|uniprotkb:UCRP(gene name synonym)|uniprotkb:Interferon-induced 15 kDa protein(gene name synonym)|uniprotkb:Interferon-induced 17 kDa protein(gene name synonym)|uniprotkb:Ubiquitin cross-reactive protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_005092.1|ensembl:ENSG00000187608(gene)|ensembl:ENST00000649529(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009615"(response to virus)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031386"(protein tag)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0032461"(positive regulation of protein oligomerization)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0070585"(protein localization to mitochondrion)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|mint:P05161|rcsb pdb:1Z2M|rcsb pdb:2HJ8|rcsb pdb:3PHX|rcsb pdb:3PSE|rcsb pdb:3R66|rcsb pdb:3RT3|rcsb pdb:3SDL|rcsb pdb:5TL6|rcsb pdb:5W8T|rcsb pdb:5W8U|rcsb pdb:6BI8|rcsb pdb:6FFA|rcsb pdb:6XA9|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-909733|reactome:R-HSA-936440|dip:DIP-29814N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:k01VuKv72XNTX3hhlIT4Lr0Xl849606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P01037 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1056240|uniprotkb:Q96LE6|uniprotkb:Q9UCQ6|ensembl:ENSP00000305731|ensembl:ENSP00000381439 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cytn_human(display_long)|uniprotkb:CST1(gene name)|psi-mi:CST1(display_short)|uniprotkb:Cystatin-1(gene name synonym)|uniprotkb:Salivary cystatin-SA-1(gene name synonym)|uniprotkb:Cystain-SA-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001889.2|ensembl:ENSG00000170373(gene)|ensembl:ENST00000304749(transcript)|ensembl:ENST00000398402(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|mint:P01037 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Ex6G/NAuwbF8h/4r104dm89B36M9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O95817 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O95036 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-6190520 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:o95036_human(display_long)|uniprotkb:"WUGSC:H_RG054D04.1"(gene name)|psi-mi:"WUGSC:H_RG054D04.1"(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR018038|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/Wx1NRwTL4OL8HlPLKeaZ568pCA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O94925 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001243239.1|refseq:NP_055720.3|dip:DIP-50591N|ensembl:ENSG00000115419(gene)|ensembl:ENST00000320717(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:4O7D|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|rcsb pdb:6ULJ - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O75531 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O75390 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O75312 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-714894|uniprotkb:Q2TAA0|ensembl:ENSP00000227322 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:zpr1_human(display_long)|uniprotkb:ZPR1(gene name)|psi-mi:ZPR1(display_short)|uniprotkb:ZNF259(gene name synonym)|uniprotkb:Zinc finger protein 259(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001304015.1|ensembl:ENSG00000109917(gene)|ensembl:ENST00000227322(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001834"(trophectodermal cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0021510"(spinal cord development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030576"(Cajal body organization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042023"(DNA endoreduplication)|refseq:NP_003895.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061564"(axon development)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1990261"(pre-mRNA catabolic process)|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR004457(Zinc finger, ZPR1-type)|interpro:IPR040141|interpro:IPR042451|interpro:IPR042452|go:"GO:0042307"(positive regulation of protein import into nucleus) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:q3p6D9KgDuPSHw0+Y5fy/WhAHkc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O43324 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O15116 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O14980 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O14949 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-720294|uniprotkb:Q5FVE2|uniprotkb:Q9BV88|uniprotkb:Q9T2V7|ensembl:ENSP00000367934|ensembl:ENSP00000367936|ensembl:ENSP00000367939 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:qcr8_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 8(gene name synonym)|uniprotkb:UQCRQ(gene name)|psi-mi:UQCRQ(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_055217.2|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004205(UcrQ)|interpro:IPR036642|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|ensembl:ENST00000378665(transcript)|ensembl:ENST00000378667(transcript)|ensembl:ENST00000378670(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|ensembl:ENSG00000164405(gene)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:z3gRHzrSJVEiHxsbAKU0jHYkMIc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O00442 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1045306|intact:EBI-2513784|uniprotkb:Q5VVL5|uniprotkb:Q5VVL6|uniprotkb:Q96E99|ensembl:ENSP00000359146 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rtca_human(display_long)|uniprotkb:RTCA(gene name)|psi-mi:RTCA(display_short)|uniprotkb:RNA terminal phosphate cyclase domain-containing protein 1(gene name synonym)|uniprotkb:RPC(gene name synonym)|uniprotkb:RPC1(gene name synonym)|uniprotkb:RTC1(gene name synonym)|uniprotkb:RTCD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001124313.1|refseq:NP_003720.1|ensembl:ENSG00000137996(gene)|ensembl:ENST00000370128(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003963"(RNA-3'-phosphate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR017770(RNA 3'-terminal phosphate cyclase, subgroup)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ELSeAyecjkIjaXMbCgL1j2HSTrQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O00299 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7ERZ3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879810|ensembl:ENSP00000468476 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7erz3_human(display_long)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000105355(gene)|ensembl:ENST00000589163(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|interpro:IPR004279(Perilipin) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:5cxGDxXcNK3HOuqWrFnEk1Ndzzc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EPV0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879802|ensembl:ENSP00000467546 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7epv0_human(display_long)|uniprotkb:COA3(gene name)|psi-mi:COA3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000183978(gene)|ensembl:ENST00000586680(transcript)|interpro:IPR018628 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:TbpdgQyus6M04oWd4RZdesrq/MQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EP67 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879791|ensembl:ENSP00000467249 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7ep67_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000108883(gene)|ensembl:ENST00000590124(transcript)|go:"GO:0005525"(GTP binding)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pGPpDY7B5sr3HR99dQXIoVensK09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7ENT6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21257974|ensembl:ENSP00000467087 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7ent6_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000167460(gene)|ensembl:ENST00000586833(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:XP_011526533.1|refseq:XP_016882678.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:jIv0VHn6SEMHjGl4RfAAdcgdIN89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EN27 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-25647364|ensembl:ENSP00000466756 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7en27_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007338"(single fertilization)|go:"GO:0045121"(membrane raft)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|ensembl:ENSG00000116288(gene)|ensembl:ENST00000469225(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qeDn3/xlwXmLLFCooBOeTaMZofE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7ELZ9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879781|ensembl:ENSP00000466296 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7elz9_human(display_long)|uniprotkb:NCLN(gene name)|psi-mi:NCLN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000125912(gene)|ensembl:ENST00000592737(transcript)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|interpro:IPR016574(Nicalin) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:MxW58em56mffMjAUkSn4FdY5wZY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7ELC7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26519491|ensembl:ENSP00000466019 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7elc7_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000131469(gene)|ensembl:ENST00000586277(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:sY/e/2jPIUJK12kkFbmdm5zxboY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EJM5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879766|ensembl:ENSP00000465240 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7ejm5_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000120948(gene)|ensembl:ENST00000473118(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:QVPvmCcL2GmmXMmvf6qZfQJtJ4w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EJB5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879752|ensembl:ENSP00000465101 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7ejb5_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000125743(gene)|ensembl:ENST00000585392(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:DAnz0TUkErv7bhMenHcVwlRZM+A9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:K7EJ44 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879739|ensembl:ENSP00000465019 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:k7ej44_human(display_long)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:hCG_32691(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000108518(gene)|ensembl:ENST00000574872(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR036140 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Yu4GSo4Z34qAFW6YuNxujSrJeNc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9H6X2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-905643|uniprotkb:Q96P02|uniprotkb:Q9NVP3|uniprotkb:J7K7G4|uniprotkb:J7KF88|uniprotkb:A8K7U8|uniprotkb:Q4ZFV6|uniprotkb:Q53QD8|intact:EBI-28987980|ensembl:ENSP00000301945 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:antr1_human(display_long)|uniprotkb:ANTXR1(gene name)|psi-mi:ANTXR1(display_short)|uniprotkb:ATR(gene name synonym)|uniprotkb:TEM8(gene name synonym)|uniprotkb:Tumor endothelial marker 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_060623.2|refseq:NP_115584.1|refseq:NP_444262.1|ensembl:ENSP00000301945|ensembl:ENST00000409349|ensembl:ENSP00000386494|ensembl:ENST00000409829|ensembl:ENSP00000387058|ensembl:ENST00000463335|ensembl:ENSP00000506719|ensembl:ENSG00000169604(gene)|ensembl:ENST00000303714(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022414"(reproductive process)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:1901202"(negative regulation of extracellular matrix assembly)|go:"GO:1901998"(toxin transport)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008399(Anthrax toxin receptor, C-terminal)|interpro:IPR008400(Anthrax toxin receptor, extracellular)|interpro:IPR017360(Anthrax toxin receptor 2)|interpro:IPR036465|rcsb pdb:3N2N|rcsb pdb:6ADL|rcsb pdb:6ADM|rcsb pdb:6ADR|rcsb pdb:6CX1|reactome:R-HSA-5210891 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:AtdL6Qm9CaH6Eb00jQly4K04AFg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:J3QR88 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879726|ensembl:ENSP00000464098 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:j3qr88_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000183010(gene)|ensembl:ENST00000577624(transcript)|go:"GO:0008652"(cellular amino acid biosynthetic process)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:8NelMLdVkLybYLLi/2ZlpV8c5Yw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:J3QLR8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879713|ensembl:ENSP00000463677 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:j3qlr8_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000181610(gene)|ensembl:ENST00000578444(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR019520|interpro:IPR023611 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:mW4E3JC3FJj/ltGzEvP1i5GrDpw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:I3L4Q1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879701|ensembl:ENSP00000461436|ensembl:ENSP00000468130 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:i3l4q1_human(display_long)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000575110(transcript)|ensembl:ENST00000589878(transcript)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR025609 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+x/9Ox4KWKx2iFrjDi/C1nrmtJM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:I3L3E9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879688|ensembl:ENSP00000460402 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:i3l3e9_human(display_long)|uniprotkb:FEN1(gene name)|psi-mi:FEN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000168496(gene)|ensembl:ENST00000535307(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR036279 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:rIo7PfvndLY9MQkeWezDdypWHT49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:I3L0M9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879675|ensembl:ENSP00000458213 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:i3l0m9_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000103363(gene)|ensembl:ENST00000494946(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0030891"(VCB complex)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:aXG99GcPPltxVuJJ2c92JSu5I0A9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:I0CE67 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879667 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:i0ce67_human(display_long)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0046872"(metal ion binding)|interpro:IPR037987|interpro:IPR001781(Zinc finger, LIM-type) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:k7GnhJyHinVsi8lXqSFYNt04CxY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H7C5W9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879646|ensembl:ENSP00000449454 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h7c5w9_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000174437(gene)|ensembl:ENST00000548169(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|go:"GO:0033017"(sarcoplasmic reticulum membrane) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IeKnY/rmXKr6MBWoOfg3eZklhc09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H7C367 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879633|ensembl:ENSP00000409773 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h7c367_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000147140(gene)|ensembl:ENST00000418921(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR035979 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:b7MEUQun3Uc6ALoY4xfXMxdzy2w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H7C125 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879622|ensembl:ENSP00000398054 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h7c125_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENST00000452437(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|ensembl:ENSG00000104388(gene) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:bw1IcbxiFSAhqASy+XFVJoScafw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H7BY36 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-20722907|ensembl:ENSP00000353204 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h7by36_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000182944(gene)|ensembl:ENST00000360091(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ebqFOBv0lL2CtPEBpnrWbCMiNZs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H7BXY3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879598|ensembl:ENSP00000343442 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h7bxy3_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000132153(gene)|ensembl:ENST00000348968(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|refseq:NP_001317919.1|refseq:XP_011531798.1|refseq:XP_011531799.1|refseq:XP_011531800.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:OsQTXwm2cKj+L0OLahkZRG+fkCo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H3BSK9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879589|ensembl:ENSP00000456752 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h3bsk9_human(display_long)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENST00000568266(transcript)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR025852|ensembl:ENSG00000168488(gene) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:HavYKjnyL7zMtkW+icPMzS2Xuhk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H3BPE3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879577|ensembl:ENSP00000455277 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h3bpe3_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000184110(gene)|ensembl:ENST00000568426(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0031369"(translation initiation factor binding)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qvMqUBvtlYMOLal3qwpNDHWuOA49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H3BNI9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879565|ensembl:ENSP00000454874 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h3bni9_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000070770(gene)|ensembl:ENST00000565188(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_005255857.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:sJrg+SNuTj5RIsO2IjlKygOupD89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q06323 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-712149|uniprotkb:H0YNE3|ensembl:ENSP00000206451|ensembl:ENSP00000495095|uniprotkb:Q9UEF4|uniprotkb:Q6IBM2|uniprotkb:A6NJG9 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:psme1_human(display_long)|uniprotkb:Proteasome activator 28 subunit alpha(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 1(gene name synonym)|uniprotkb:11S regulator complex subunit alpha(gene name synonym)|uniprotkb:Interferon gamma up-regulated I-5111 protein(gene name synonym)|uniprotkb:PSME1(gene name)|psi-mi:PSME1(display_short)|uniprotkb:IFI5111(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 reactome:R-HSA-5678895|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-5687128|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|ensembl:ENSG00000092010(gene)|ensembl:ENSG00000284916(gene)|ensembl:ENST00000206451(transcript)|ensembl:ENST00000645537(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0019884"(antigen processing and presentation of exogenous antigen)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q06323|rcsb pdb:1AVO|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|refseq:NP_006254.1|refseq:NP_001268457.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:kyTjI3VP2S7Bvwq4R0pJudnlOC09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YN88 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879548|ensembl:ENSP00000453910|ensembl:ENSP00000488464 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0yn88_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000561157(transcript)|ensembl:ENST00000632419(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:VMZWtJ5GKyHeGv0Ws7Rg1Rc+JvQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YJX2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879534|ensembl:ENSP00000452388 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0yjx2_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100519(gene)|ensembl:ENST00000555175(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|interpro:IPR035263 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qqAWfHEhkvhFJst7dICz7qCqyPs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YJU2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879520|ensembl:ENSP00000452127 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0yju2_human(display_long)|uniprotkb:AHSA1(gene name)|psi-mi:AHSA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100591(gene)|ensembl:ENST00000555729(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR036338|interpro:IPR039981 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:1ZtV/5jelL8k38oHD7l9NChry7g9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YHI8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879513|ensembl:ENSP00000447144 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0yhi8_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000058272(gene)|ensembl:ENST00000553081(transcript) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:p93A4E8kSn69NUeQoHPTCEIUEIQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YGV8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879504|ensembl:ENSP00000444980 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0ygv8_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000108344(gene)|ensembl:ENST00000540504(transcript)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR035267 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:P4iH6/to7ieeRGX9aYw2t8eWYTg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0YG82 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879493|ensembl:ENSP00000442137 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0yg82_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000061794(gene)|ensembl:ENST00000542199(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR039848 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:y1qZzSJi1UWZ1V0GBFrnALiQiaQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:H0UIA5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879484 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:h0uia5_human(display_long)|uniprotkb:SCAND1(gene name)|psi-mi:SCAND1(display_short)|uniprotkb:hCG_38222(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005634"(nucleus)|refseq:NP_361012.2|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR038269 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:vwZYSmJArLa3+ZyeA3qS44acSfg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O76094 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P46779 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:G3V3M5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879475|ensembl:ENSP00000451326 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:g3v3m5_human(display_long)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000133961(gene)|ensembl:ENST00000555859(transcript)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:luWEftFEE4gnC6IhcjSSZDEt8EA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9NPA8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F8WE39 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879461|ensembl:ENSP00000402163 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f8we39_human(display_long)|uniprotkb:ARPC4-TTLL3(gene name)|psi-mi:ARPC4-TTLL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000250151(gene)|ensembl:ENST00000418163(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042995"(cell projection)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/aCUwJGznZ6LmAbTa9almtyT+lM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F8WBG6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879452|ensembl:ENSP00000418025 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f8wbg6_human(display_long)|uniprotkb:TM4SF1(gene name)|psi-mi:TM4SF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000169908(gene)|ensembl:ENST00000493298(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008661(L6 membrane) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:czVSbvgBx82dtkseT9MuGtf9KFE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F8W1G0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879441|ensembl:ENSP00000447472 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f8w1g0_human(display_long)|uniprotkb:ERP29(gene name)|psi-mi:ERP29(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000089248(gene)|ensembl:ENST00000552052(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009306"(protein secretion)|interpro:IPR012883(ERp29, N-terminal) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NZLI+G3uNUPdsFaU9PpKtvaRUVk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F8VZ45 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879429|ensembl:ENSP00000446883 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f8vz45_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000089009(gene)|ensembl:ENST00000549847(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:iIspIyZoOLSp//DRNgQk9dGL1OQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F8VXH9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879418|ensembl:ENSP00000448847 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f8vxh9_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000197111(gene)|ensembl:ENST00000550520(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Oufb+qmYEMJCIokdWGkxpUPTEhk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F6KRM6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879410 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f6krm6_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR037055|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:fbAqCAl4g+QIMWPzEtHnIZI/AJE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F5H6H0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879395|ensembl:ENSP00000437621 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f5h6h0_human(display_long)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000149948(gene)|ensembl:ENST00000536545(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|refseq:NP_001287848.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:1F85eImAG8ah0l88GkH6KkNdIz49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F5H169 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879385|ensembl:ENSP00000443968 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f5h169_human(display_long)|uniprotkb:PSMD9(gene name)|psi-mi:PSMD9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000110801(gene)|ensembl:ENST00000535293(transcript)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR035269|interpro:IPR040815 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:6txJZ8gxbjf3NiOodwsZ8dGqZ5Q9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F5H157 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879373|ensembl:ENSP00000443994 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f5h157_human(display_long)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000111737(gene)|ensembl:ENST00000538903(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:K5977BhP8qW34OFNiqC+2fo/tmQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:F5GX39 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879358|ensembl:ENSP00000441161 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:f5gx39_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000086598(gene)|ensembl:ENST00000509052(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:EnKY4JRCI8et/pfNloWRZqX1LFc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q8WWY3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1567797|uniprotkb:Q8N7F9|uniprotkb:Q9H271|uniprotkb:Q9Y439|uniprotkb:Q17RB4|intact:EBI-10177194|uniprotkb:F1T0A5|uniprotkb:E7ESA8|uniprotkb:F1T0A4|ensembl:ENSP00000324122|ensembl:ENSP00000483929 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:prp31_human(display_long)|uniprotkb:Pre-mRNA-processing factor 31(gene name synonym)|uniprotkb:U4/U6 snRNP 61 kDa protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-99(gene name synonym)|uniprotkb:PRPF31(gene name)|psi-mi:PRPF31(display_short)|uniprotkb:PRP31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:XP_006723200.1|refseq:NP_056444.3|ensembl:ENSG00000105618(gene)|ensembl:ENSG00000275885(gene)|ensembl:ENST00000321030(transcript)|ensembl:ENST00000613693(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR012976(NOSIC)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070990"(snRNP binding)|interpro:IPR019175|interpro:IPR027105|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071166"(ribonucleoprotein complex localization)|interpro:IPR036070|interpro:IPR042239|mint:Q8WWY3|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NsXY3tY7Y2EEK8rxoisqlfpzuf89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P46977 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PLD3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-11069715|ensembl:ENSP00000435188 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pld3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR037691|ensembl:ENSG00000255432(gene)|ensembl:ENST00000528405(transcript) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:iUSmjd2roGizUINccsCQiCyeGbM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PJ81 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879345|ensembl:ENSP00000435625 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pj81_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000162191(gene)|ensembl:ENST00000534176(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pzyT0aczS7SMskvOFfyMMrDsS/U9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PIK5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879333|ensembl:ENSP00000435798 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pik5_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000023191(gene)|ensembl:ENST00000531149(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|interpro:IPR041302 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IHO6elkr8IYExB3BeUgcqNg0fNU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PI41 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879319|ensembl:ENSP00000436539 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pi41_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000178896(gene)|ensembl:ENST00000527954(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:4SlJynRCzgUPiwNgtnt5nyun3ok9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P14324 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PBD2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879305|ensembl:ENSP00000424059|ensembl:ENSP00000424435 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pbd2_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000109814(gene)|ensembl:ENST00000503779(transcript)|ensembl:ENST00000510881(transcript)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR028356|interpro:IPR036291 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pj/JH+hdg45sxb+XiUm8uygyLzU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E9PB51 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879290|ensembl:ENSP00000422301 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e9pb51_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000173933(gene)|ensembl:ENST00000510173(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:KJvdI/Su3ihYVqpSwkxd9eqhA5k9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E5RJU9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879277|ensembl:ENSP00000428168 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e5rju9_human(display_long)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000147649(gene)|ensembl:ENST00000519934(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|interpro:IPR031402 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:H2HVQxJPlRGtdz5csG2mZoEUiDE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:E5RIP7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879259|ensembl:ENSP00000429322 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:e5rip7_human(display_long)|uniprotkb:IMPA1(gene name)|psi-mi:IMPA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000133731(gene)|ensembl:ENST00000519964(transcript)|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020552|interpro:IPR020583|interpro:IPR033942 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:tKAeh4GslNooN595Qt++1pF5mjc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D6W5C0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-11601803 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d6w5c0_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:hCG_17370(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR002017(Spectrin repeat)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0008091"(spectrin)|go:"GO:0051693"(actin filament capping)|interpro:IPR041681|interpro:IPR036872 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ca4mhGJwuUVZ2bYl95Y7zRlkoUY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D6REM1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879248|ensembl:ENSP00000426752 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d6rem1_human(display_long)|uniprotkb:GOLPH3(gene name)|psi-mi:GOLPH3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000113384(gene)|ensembl:ENST00000503610(transcript)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR008628(Golgi phosphoprotein 3) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:rMz6UPSX+XtVCOu/5tNwXieL3oc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D6RAN4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879233|ensembl:ENSP00000421872 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d6ran4_human(display_long)|uniprotkb:RPL9(gene name)|psi-mi:RPL9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000163682(gene)|ensembl:ENST00000503040(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:6DaaQaVRyM4Ll74N78bXZxenY5Q9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D6RAC2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879218|ensembl:ENSP00000422768 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d6rac2_human(display_long)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000204628(gene)|ensembl:ENST00000511900(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|go:"GO:0005654"(nucleoplasm)|interpro:IPR020472|interpro:IPR036322 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:EgJTjyuOr0foVzpHt040SbFtJ+09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D6R970 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879211|ensembl:ENSP00000423356 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d6r970_human(display_long)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000113387(gene)|ensembl:ENST00000511615(transcript) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/ZxyYUN0FhZMuLdTBAgjwMmZO589606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:D3DQU2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879199 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:d3dqu2_human(display_long)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)|uniprotkb:Tripeptidyl-peptidase 1(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:hCG_22005(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR036852|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:vJQKEGivYzhIDefgjvhhV1CYYsY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9K0Q7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879189|ensembl:ENSP00000393822 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9k0q7_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100129(gene)|ensembl:ENST00000414316(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|interpro:IPR019382 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pLi/ZIRYgdCCbCyGt0SkOU5939o9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9JUL4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879176|ensembl:ENSP00000399494 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9jul4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000162616(gene)|ensembl:ENST00000426517(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ucsRyorEeDA4lOOSJO+Lhj4ZtRY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9JH92 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879161|ensembl:ENSP00000404289 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9jh92_human(display_long)|uniprotkb:CRYZ(gene name)|psi-mi:CRYZ(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000116791(gene)|ensembl:ENST00000441120(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+DuSrR4MXo/Kc4Bia2eJliH3spk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9JEV0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879150|ensembl:ENSP00000396093 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9jev0_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000160862(gene)|ensembl:ENST00000411734(transcript)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:muBdVU/vv5H6m3U7pJVFZykwFCs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P52434 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9J8H1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879139|ensembl:ENSP00000398932 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9j8h1_human(display_long)|uniprotkb:ATP6V1E1(gene name)|psi-mi:ATP6V1E1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000131100(gene)|ensembl:ENST00000413576(transcript)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Y4jajhjgXkRBcITdi4L9/kOTnrQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9J5S7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879126|ensembl:ENSP00000405975 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9j5s7_human(display_long)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000196262(gene)|ensembl:ENST00000451562(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:s1Lz6+p/80rI9nDeXpXXZaAMAAs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P55327 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9J4Z3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879112|ensembl:ENSP00000410240 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9j4z3_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:hCG_16380(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000197756(gene)|ensembl:ENST00000456586(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0nxdml251Ald69ggi8cUJOsn90U9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9J4U1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879096|ensembl:ENSP00000417166 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9j4u1_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000114030(gene)|ensembl:ENST00000482287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036975 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:p/F5arEzw/K/YZzl2kmi/mTjtDg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C9J0D1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-25627436|ensembl:ENSP00000406901 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c9j0d1_human(display_long)|uniprotkb:H2AZ2(gene name)|psi-mi:H2AZ2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENST00000446531(transcript)|ensembl:ENSG00000105968(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032458 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:t2WBtqUBJLpRTMpzYBkdCRg1iio9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:C4P0D4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879078|ensembl:ENSP00000473307|ensembl:ENSP00000493799|ensembl:ENSP00000494923|ensembl:ENSP00000496433 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:c4p0d4_human(display_long)|uniprotkb:TSNAX-DISC1(gene name)|psi-mi:TSNAX-DISC1(display_short)|uniprotkb:DISC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000270106(gene)|ensembl:ENST00000602634(transcript)|ensembl:ENST00000644515(transcript)|ensembl:ENST00000646525(transcript)|ensembl:ENST00000647072(transcript)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|interpro:IPR036081 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:m4Y2xPez3GSGCkdfZvkBs0vAfLw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7ZW15 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879070 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7zw15_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0006096"(glycolytic process)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|interpro:IPR005952(Phosphoglycerate mutase 1) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:YP45QQe0lPUTaw0zNecsjSD9HEs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P30044 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P61204 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-641535|uniprotkb:P16587|uniprotkb:A8K6G8|ensembl:ENSP00000256682|ensembl:ENSP00000438510|uniprotkb:B7ZB63 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:arf3_human(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001650.1|ensembl:ENSG00000134287(gene)|ensembl:ENST00000256682(transcript)|ensembl:ENST00000541959(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61204|rcsb pdb:6II6|reactome:R-HSA-1660514|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_005268913.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:np09WjdbXRu9vgMbiXn9EA3ExqA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9UBQ5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7ZAF0 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879052 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7zaf0_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|interpro:IPR002453(Beta tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR037103|interpro:IPR036525|interpro:IPR023123|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:e4LlUIVTngBy/LYuYFIlBC6cDpc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7ZAC7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879045 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7zac7_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR037231|interpro:IPR002164("Nucleosome assembly protein (NAP)") - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:LxwRnMHK0kU/mFwn6K7b0BM6ms09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7Z9C4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879037 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7z9c4_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003883"(CTP synthase activity)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR027417 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:EcVVm15ApD7c1JOy9TIwcTJT4lY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y4L1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P50991 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q02413 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7Z6J7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879021|ensembl:ENSP00000496602 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7z6j7_human(display_long)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000088038(gene)|ensembl:ENST00000617930(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030015"(CCR4-NOT core complex)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:TW0Hp7nJ8F3q7AHxTNVOLJq/IXc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B7Z4N6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879009|uniprotkb:C9J0X6 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b7z4n6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|interpro:IPR026729|interpro:IPR030514|interpro:IPR000956(Stathmin)|interpro:IPR036002 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:UoirukRcCLkqsyhf7mP/pPb/qNg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P18621 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9BZZ5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:WYNbM5GNolgFNszccnMEanszDgU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E229 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26879002 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e229_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001193946.1|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR022189 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:g+4u3SOeGMqHQLpfURdn05yFe7o9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E1R7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878982 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e1r7_human(display_long)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Calpain-2 catalytic subunit(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0005886"(plasma membrane)|interpro:IPR033883|interpro:IPR022684|interpro:IPR022682|interpro:IPR022683|interpro:IPR036213|interpro:IPR029539|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR042736|interpro:IPR038765|interpro:IPR001300(Peptidase C2, calpain) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IfqJS/CVZ+EQVk1I1MFReO3C+Nc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E1Q7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878974 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e1q7_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR023213|interpro:IPR036625|interpro:IPR004167(E3 binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:GY8a/N4guA40uckYyyqr1xhq8w89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E1D9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878966 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e1d9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:PVlNoXxqUqglKR+cvYOyg7YxnR09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E0R6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21448491 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e0r6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR040122|interpro:IPR041653|interpro:IPR041389|interpro:IPR034085|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR040928 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:VddzzlE/w1E2ABfNzOsuY/JIvoY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4E0E1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21448712 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4e0e1_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR012982(PADR1)|interpro:IPR038650|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR036616|interpro:IPR036930|interpro:IPR008893(WGR)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR036957|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0003677"(DNA binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:PHAK+Ido+4ACsSbUcfbciERUsCA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DZW9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878960 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dzw9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003824"(catalytic activity)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:F6wByIOT3AFTaTj5IRGEsLka4PQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:O43237 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-715294|uniprotkb:Q8TAT3|uniprotkb:A8K6V1|uniprotkb:B4DZP4|ensembl:ENSP00000258198 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dc1l2_human(display_long)|uniprotkb:Dynein light intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:LIC53/55(gene name synonym)|uniprotkb:DYNC1LI2(gene name)|psi-mi:DYNC1LI2(display_short)|uniprotkb:LIC2(gene name synonym)|uniprotkb:DNCLI2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_006132.1|refseq:NP_001273086.1|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0051642"(centrosome localization)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|rcsb pdb:6F1T|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|ensembl:ENSG00000135720(gene)|ensembl:ENST00000258198(transcript) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:WUEd3zgPhcKEe10gtoJ+okX8Zps9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q9Y697 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DV73 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878953 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dv73_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:LnfMkAThJCpYQYL4D8Ag5+xx9d89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DUA4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-11602554|ensembl:ENSP00000450918|ensembl:ENSP00000452449|ensembl:ENSP00000474409 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dua4_human(display_long)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100650(gene)|ensembl:ENST00000553369(transcript)|ensembl:ENST00000554021(transcript)|ensembl:ENST00000555547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:hh4peS/NRH9N0IY5QNs8is5a4SE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DTA2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878942 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dta2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR034847|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:oys5xdGzsWlw7JynpUweC3esSnA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DRT3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-4287252 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4drt3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR036918|interpro:IPR015806(Pyruvate kinase, beta-barrel)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0016301"(kinase activity)|interpro:IPR040442 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:zT6hsqLrYD3Brbi5hSb/oAZPr5U9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:Q12931 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P49588 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-709710|uniprotkb:A6NF14|uniprotkb:Q53GV7|uniprotkb:Q96FA0|uniprotkb:B4DR45|ensembl:ENSP00000261772|ensembl:ENSP00000501924|ensembl:ENSP00000502247|ensembl:ENSP00000502797 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:syac_human(display_long)|uniprotkb:AARS1(gene name)|psi-mi:AARS1(display_short)|uniprotkb:AARS(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001596.2|ensembl:ENSG00000090861(gene)|ensembl:ENST00000261772(transcript)|ensembl:ENST00000674691(transcript)|ensembl:ENST00000674963(transcript)|ensembl:ENST00000675643(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0002196"("Ser-tRNA(Ala) hydrolase activity")|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016597"(amino acid binding)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140018"(regulation of cytoplasmic translational fidelity)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:P49588|rcsb pdb:4XEM|rcsb pdb:4XEO|rcsb pdb:5KNN|rcsb pdb:5T5S|rcsb pdb:5T76|rcsb pdb:5V59|reactome:R-HSA-379716 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:e9+gLroLXvK8li0wiPBGbZhQqP49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DQY2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878936 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dqy2_human(display_long)|uniprotkb:Mitofilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019133 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:lXM8i8kHj5OLK2sZN97zNgbkz/I9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DQI7 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878930 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dqi7_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001189431.1|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:B9vi3nEj80ivoJEA1tse9umncGs9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DPS6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878921 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dps6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR013713(Exportin, Cse1-like) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:pBpwXeiR6btsH5mLy0oDTJwHN7U9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DP77 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878913 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dp77_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005763"(mitochondrial small ribosomal subunit)|refseq:XP_016866485.1|interpro:IPR040055|interpro:IPR027486|interpro:IPR036838 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0YdZ6peHiDhR7JEf1ztF1BtWpwo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P51659 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DNS4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878909 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dns4_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0016021"(integral component of membrane) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:8RjVvXwf5/2dCNycz1e3Qh/cMV49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DNL5 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878898 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dnl5_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR036249|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0OyT3ncdaRl8VGVKr255OnNkCUc9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DNA3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878880 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dna3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR017901|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR028415|interpro:IPR036223|interpro:IPR028417|interpro:IPR018106|interpro:IPR036222|interpro:IPR006599(CARP motif) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:N8EaqgzkOJBw6MP1jnBIyp1JiM09606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DN87 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878865 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dn87_human(display_long)|uniprotkb:Serpin H1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR023795|interpro:IPR023796|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|interpro:IPR033547 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:M8DRwhDA5WCOMYa4YM669RheReo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DJ66 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21262784 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dj66_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:hCG_37689(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000502"(proteasome complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:biPjxPsOaUM79xLrZSIgfdxk/S49606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DH39 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878857 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dh39_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0016021"(integral component of membrane)|go:"GO:0016874"(ligase activity)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR042099 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:IVfL5swidu6qe0dN+RECueIcb0E9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DF61 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878841 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4df61_human(display_long)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR041872|interpro:IPR023458|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR033911|interpro:IPR029038|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:7a48MogN2Znvm6iCCFRkgknQmCo9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DEZ3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878829|ensembl:ENSP00000468317 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dez3_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000186010(gene)|ensembl:ENST00000503283(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070469"(respirasome)|interpro:IPR009346(GRIM-19) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:uHwur7Zir7cA7iieU1pz0fFWo8w9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DEM9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878815|ensembl:ENSP00000477665|uniprotkb:A0A087WT81 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4dem9_human(display_long)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000004142(gene)|ensembl:ENST00000618887(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|refseq:NP_001277074.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:E34w+1IiPGudrM2DZ1jLHcJ+xas9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P61006 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DE78 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878808 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4de78_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR036815|interpro:IPR023410 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:NYsZ+bXNoWz/yng5Oe+iZDX23BU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DDX2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-9985676 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4ddx2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR032335|interpro:IPR032571|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0CGIX/NgxG68XSeTpfFQvKzLmzw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B4DDL9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878798 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b4ddl9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_001277159.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:FgVv8nh/eN4WsI9r8COQ3IUHhCg9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B3KW56 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-25602041|ensembl:ENSP00000430678|ensembl:ENSP00000504404|ensembl:ENSP00000504521|ensembl:ENSP00000504815|uniprotkb:E5RIT4 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b3kw56_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:INT6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:hCG_2008794(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000104408(gene)|ensembl:ENST00000518345(transcript)|ensembl:ENST00000677040(transcript)|ensembl:ENST00000677409(transcript)|ensembl:ENST00000678881(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:FiLdlZiiCq4o/ICLDjPtu0bGzDM9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B3KVX6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878794 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b3kvx6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR028428 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:bgE2MsGc+Ip05fp5uSCjaLNJQIE9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B3KT18 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878781 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b3kt18_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0000166"(nucleotide binding)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006520"(cellular amino acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR033524|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR014362(Glutamate dehydrogenase)|interpro:IPR036291|interpro:IPR033922 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:isax+aHw5E/bnYgBOOvmAn4IG5s9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B3KSS1 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878767 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b3kss1_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR032420|interpro:IPR032418|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018965|interpro:IPR038252|interpro:IPR019572|interpro:IPR042063|interpro:IPR035985|interpro:IPR018075 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:MCT/sroQyhV3wKWjj9VjrYQLCoU9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B3KRA9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878753 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b3kra9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0006096"(glycolytic process)|go:"GO:0019318"(hexose metabolic process)|interpro:IPR043129|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022673|interpro:IPR022672 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:eRRtmZOGnOSfYp5uW/bco3U+nj89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B2RU06 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878737 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b2ru06_human(display_long)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|refseq:NP_001181875.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:qsOU5kG4JDaRmPZUkMhWKXb91ss9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:P60891 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:+Hih2M7JLTsjEglauBlPj182h9M9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B2R602 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26662212 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b2r602_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_001130047.1|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR020464 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:0ZXtKs4kM5+Axj2H22HMSXH9kfk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B2R4V2 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878729 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b2r4v2_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:KDN7pKKVZ9R3EX0AuuWmyNBRTuk9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B2R4I8 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21355273 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b2r4i8_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0030123"(AP-3 adaptor complex)|interpro:IPR027155|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:f4vR7hK+iAQA8E5xC3YDt4DUTe89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B2C310 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878723 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b2c310_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0016740"(transferase activity)|interpro:IPR036282 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:XrV06DkPGwypuNpUSbyg4RmrBY89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B1APP6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878704|ensembl:ENSP00000408858 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b1app6_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|ensembl:ENSG00000067057(gene)|ensembl:ENST00000415005(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|refseq:NP_001310002.1|refseq:NP_001310003.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:HsxC0TJqhvGuKiyJMvlBcV7B/Kw9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B1AH87 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-11065131|ensembl:ENSP00000405685 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b1ah87_human(display_long)|uniprotkb:TSPO(gene name)|psi-mi:TSPO(display_short)|uniprotkb:Translocator protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000100300(gene)|ensembl:ENST00000428336(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR004307(TspO/MBR-related protein)|interpro:IPR030164|interpro:IPR038330 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:Siy0A7S8voUbkzAkFrqGWI1IboA9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:B0AZT6 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878697 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:b0azt6_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 refseq:NP_001316684.1|refseq:NP_001316686.1|refseq:NP_001316687.1|interpro:IPR008560(Protein of unknown function DUF842, eukaryotic) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:wxThghjyN56grBWzqgxUwe7gwWY9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:A8K9K4 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878688 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:a8k9k4_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0009311"(oligosaccharide metabolic process)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR004888(Glycoside hydrolase, family 63) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:uZB9rl+EAqer07YP2kXSRmmobxQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:A8K4K9 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-21352166 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:a8k4k9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 go:"GO:0072546"(EMC complex)|interpro:IPR039856|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:r1bJln2uVcChbiIyc+ar6xclLw89606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:A6NDF3 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-26878677|ensembl:ENSP00000362455 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:a6ndf3_human(display_long)|uniprotkb:PBDC1(gene name)|psi-mi:PBDC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 ensembl:ENSG00000102390(gene)|ensembl:ENST00000373357(transcript)|interpro:IPR008476(Protein of unknown function DUF757)|interpro:IPR021148|interpro:IPR023139|refseq:NP_001287817.1 - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:bGeBwn1g0EN9d9w6G+kE9Ruy0689606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01995 uniprotkb:A4D198 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 intact:EBI-2562867 psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:a4d198_human(display_long)|uniprotkb:LOC392647(gene name)|psi-mi:LOC392647(display_short)|uniprotkb:tcag7.1028(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26878675|imex:IM-28930-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0003723"(RNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR034229|interpro:IPR035979|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Table S1|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/04/12 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rogid:evgb4U4JGuSWYjcqE6O5T6/9fNQ9606 rigid:IhoDY/mnUdci2wsde8zNf2+ykPo false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09874 uniprotkb:Q01995 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 intact:EBI-1054248|uniprotkb:O15542|ensembl:ENSP00000278968|ensembl:ENSP00000376678|ensembl:ENSP00000431941|ensembl:ENSP00000432054|ensembl:ENSP00000432282 psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:tagl_human(display_long)|uniprotkb:Smooth muscle protein 22-alpha(gene name synonym)|uniprotkb:22 kDa actin-binding protein(gene name synonym)|uniprotkb:TAGLN(gene name)|psi-mi:TAGLN(display_short)|uniprotkb:SM22(gene name synonym)|uniprotkb:WS3-10(gene name synonym)|uniprotkb:Protein WS3-10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lew et al. (2019) pubmed:32774160|imex:IM-28930 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26880453|imex:IM-28930-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N refseq:NP_001001522.1|refseq:NP_003177.2|ensembl:ENSG00000149591(gene)|ensembl:ENST00000278968(transcript)|ensembl:ENST00000392951(transcript)|ensembl:ENST00000525531(transcript)|ensembl:ENST00000530649(transcript)|ensembl:ENST00000532870(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007517"(muscle organ development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0051015"(actin filament binding)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR029976|interpro:IPR036872 - - - figure legend:Fig. 4F|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rko)|taxid:9606(Homo sapiens colorectal carcinoma cell line) - 2021/03/18 2021/03/18 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rogid:Tz3jJmaFOAQzRJIUztjxLTgBBoE9606 rigid:wdijwCvVZqqVVBaSzXnsWZLJfi4 false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)