#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8N697	uniprotkb:O14828	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95816	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00560	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9H936	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1050588|uniprotkb:Q8TBU8|uniprotkb:A8K366|uniprotkb:C9J1H6|uniprotkb:E9PJD3|uniprotkb:E9PKB2|uniprotkb:E9PL68|uniprotkb:E9PN26|uniprotkb:E9PNQ3|uniprotkb:E9PP01|uniprotkb:E9PR97|ensembl:ENSP00000322020|ensembl:ENSP00000437236|ensembl:ENSP00000486058	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:ghc1_human(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:SLC25A22(gene name)|psi-mi:SLC25A22(display_short)|uniprotkb:GC1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001177989.1|refseq:NP_001177990.1|refseq:NP_078974.1|ensembl:ENSG00000177542(gene)|ensembl:ENST00000320230(transcript)|ensembl:ENST00000531214(transcript)|ensembl:ENST00000628067(transcript)|go:"GO:0005280"("amino acid:proton symporter activity")|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-428643|refseq:XP_011518671.1|refseq:XP_011518672.1|refseq:XP_011518673.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:B1e6uu3Vx73qy/JrHS7p63p0QMM9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95197	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q15758	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O75947	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P04792	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N	-	-	crc64:1B4DC44A6F6606D5	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O15260	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P09382	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:A0FGR8	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P48047	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95490	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|intact:EBI-28986872|ensembl:ENSP00000359752|ensembl:ENSP00000359763	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_036434.1|ensembl:ENST00000319517|ensembl:ENSP00000322270|ensembl:ENST00000359929|ensembl:ENSP00000353006|ensembl:ENST00000370713|ensembl:ENSP00000359748|ensembl:ENST00000370715|ensembl:ENSP00000359750|ensembl:ENSP00000359752|ensembl:ENST00000370723|ensembl:ENSP00000359758|ensembl:ENST00000370725|ensembl:ENSP00000359760|ensembl:ENSP00000359763|ensembl:ENST00000370730|ensembl:ENSP00000359765|ensembl:ENST00000674393|ensembl:ENSP00000501431|ensembl:ENST00000674419|ensembl:ENSP00000501462|refseq:XP_005270723.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114(gene)|ensembl:ENST00000370717(transcript)|ensembl:ENST00000370728(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0009617"(response to bacterium)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016524"(latrotoxin receptor activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031240|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P17931	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:5FijxEN6irEGIg4AtAdn6DB03e49606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O14967	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P02786	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O14929	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00214	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-740058|uniprotkb:Q5T3P5|uniprotkb:Q8TEV1|uniprotkb:Q9BXC8|uniprotkb:O15215|uniprotkb:Q96B92|uniprotkb:Q9H584|uniprotkb:Q9H585|uniprotkb:Q9UEZ6|uniprotkb:Q9UP32|uniprotkb:Q9UP33|uniprotkb:Q9UP34|uniprotkb:Q5T3Q4|ensembl:ENSP00000342139|ensembl:ENSP00000355543|ensembl:ENSP00000437040	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg8_human(display_long)|uniprotkb:LGALS8(gene name)|psi-mi:LGALS8(display_short)|uniprotkb:Prostate carcinoma tumor antigen 1(gene name synonym)|uniprotkb:Po66 carbohydrate-binding protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_006490.3|refseq:NP_963837.1|refseq:NP_963838.1|refseq:NP_963839.1|ensembl:ENSG00000116977(gene)|ensembl:ENST00000341872(transcript)|ensembl:ENST00000366584(transcript)|ensembl:ENST00000526634(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098792"(xenophagy)|go:"GO:1904977"(lymphatic endothelial cell migration)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030638|interpro:IPR044156|mint:O00214|rcsb pdb:2YRO|rcsb pdb:2YV8|rcsb pdb:2YXS|rcsb pdb:3AP4|rcsb pdb:3AP5|rcsb pdb:3AP6|rcsb pdb:3AP7|rcsb pdb:3AP9|rcsb pdb:3APB|rcsb pdb:3OJB|rcsb pdb:3VKL|rcsb pdb:3VKM|rcsb pdb:3VKN|rcsb pdb:3VKO|rcsb pdb:4BMB|rcsb pdb:4BME|rcsb pdb:4FQZ|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:5GZC|rcsb pdb:5GZD|rcsb pdb:5GZE|rcsb pdb:5GZF|interpro:IPR001079(Galectin, galactose-binding lectin)|rcsb pdb:5GZG|rcsb pdb:5T7I|rcsb pdb:5T7S|rcsb pdb:5T7T|rcsb pdb:5T7U|rcsb pdb:5VWG|rcsb pdb:6W4Z|rcsb pdb:6Z6Y	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:5PkQ2VGIKZ8Zz2CDprMHi5ras809606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P08195	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P04843	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9Y5Y0	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-9681535|uniprotkb:Q1HE16|uniprotkb:Q86XY9|uniprotkb:Q9NVR9|ensembl:ENSP00000355938	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:flvc1_human(display_long)|uniprotkb:FLVCR1(gene name)|psi-mi:FLVCR1(display_short)|uniprotkb:FLVCR(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_054772.1|ensembl:ENSG00000162769(gene)|ensembl:ENST00000366971(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048536"(spleen development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060323"(head morphogenesis)|go:"GO:0097037"(heme export)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q9Y5Y0|reactome:R-HSA-189451|reactome:R-HSA-917937	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bb6L2akAjb64NgdW94M2I3uMhxQ9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O43914	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q15043	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952|ensembl:ENSP00000370635	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:XP_011542780.1|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_016868783.1|refseq:XP_016868784.1|ensembl:ENSG00000104635(gene)|ensembl:ENST00000289952(transcript)|ensembl:ENST00000381237(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015296"("anion:cation symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033212"(iron import into cell)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055071"(manganese ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0098739"(import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|mint:Q15043|reactome:R-HSA-442380	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00182	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|ensembl:ENSP00000378856|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612323|imex:IM-28687-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|ensembl:ENSG00000168961(gene)|ensembl:ENST00000395473(transcript)|go:"GO:0002519"(natural killer cell tolerance induction)|go:"GO:0005534"(galactose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007565"(female pregnancy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016936"(galactoside binding)|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|rcsb pdb:2ZHK|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032834"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048030"(disaccharide binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070241"(positive regulation of activated T cell autonomous cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0098586"(cellular response to virus)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0019899"(enzyme binding)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|refseq:NP_001317092.1|refseq:XP_016880112.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	rigid:HJx9MT5embWv0f3imppTX7gKpG0	false	ha tag:n-n|strep tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P50281	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-992788|uniprotkb:Q6GSF3|uniprotkb:Q92678|uniprotkb:A8K5L0|ensembl:ENSP00000308208	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:mmp14_human(display_long)|uniprotkb:Membrane-type matrix metalloproteinase 1(gene name synonym)|uniprotkb:Membrane-type-1 matrix metalloproteinase(gene name synonym)|uniprotkb:MMP-X1(gene name synonym)|uniprotkb:MMP14(gene name)|psi-mi:MMP14(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENST00000311852(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010831"(positive regulation of myotube differentiation)|ensembl:ENSG00000157227(gene)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016485"(protein processing)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031638"(zymogen activation)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0044354"(macropinosome)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048870"(cell motility)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060322"(head development)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1990834"(response to odorant)|interpro:IPR000585(Hemopexin)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018486|interpro:IPR018487|interpro:IPR021158|interpro:IPR021190|interpro:IPR021805|interpro:IPR024079|interpro:IPR033739|interpro:IPR036365|interpro:IPR036366|interpro:IPR036375|mint:P50281|rcsb pdb:1BQQ|rcsb pdb:1BUV|rcsb pdb:2MQS|rcsb pdb:3MA2|rcsb pdb:3X23|rcsb pdb:4P3C|rcsb pdb:4P3D|rcsb pdb:4QXU|rcsb pdb:5H0U|rcsb pdb:6CLZ|rcsb pdb:6CM1|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|rcsb pdb:3C7X|refseq:NP_004986.1|dip:DIP-35111N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:x2H2pYgnfBvYy7Stikq3uk+ihhw9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O15427	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-7600166|uniprotkb:Q2M1P8|intact:MINT-4526381|uniprotkb:B3KXG8|ensembl:ENSP00000376150|ensembl:ENSP00000376152|ensembl:ENSP00000462405|ensembl:ENSP00000463978|ensembl:ENSP00000464112|ensembl:ENSP00000464625|ensembl:ENSP00000482013|ensembl:ENSP00000483212	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:mot4_human(display_long)|uniprotkb:SLC16A3(gene name)|psi-mi:SLC16A3(display_short)|uniprotkb:MCT4(gene name synonym)|uniprotkb:Solute carrier family 16 member 3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:XP_011521909.1|refseq:NP_001193879.1|refseq:NP_001193880.1|refseq:NP_001035888.1|refseq:NP_004198.1|refseq:NP_001035887.1|refseq:NP_001193881.1|ensembl:ENSG00000141526(gene)|ensembl:ENST00000392339(transcript)|ensembl:ENST00000392341(transcript)|ensembl:ENST00000580189(transcript)|ensembl:ENST00000581287(transcript)|ensembl:ENST00000582743(transcript)|ensembl:ENST00000584689(transcript)|ensembl:ENST00000617373(transcript)|ensembl:ENST00000619321(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030756|interpro:IPR036259|mint:O15427|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-70268	-	-	comment:mint|function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate|comment:homomint	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Ipq+K2KMGnogWD9ouLcBjZ53ICs9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95816	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00560	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95197	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-740467|intact:EBI-28977804|ensembl:ENSP00000367050|uniprotkb:Q147U9|uniprotkb:Q496K2|uniprotkb:Q53GN3|uniprotkb:Q59EP0|uniprotkb:Q5UEP2|uniprotkb:Q6T930|uniprotkb:Q7RTM7|uniprotkb:Q7RTM8|uniprotkb:Q7RTN3|uniprotkb:B3KQS2|uniprotkb:B7Z308|intact:EBI-11081390|uniprotkb:B7Z4M0|uniprotkb:F5H774	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:rtn3_human(display_long)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001252518.1|refseq:NP_006045.1|refseq:NP_958831.1|refseq:NP_958832.1|refseq:NP_958833.1|ensembl:ENSG00000133318(gene)|ensembl:ENST00000377819(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:O95197|rcsb pdb:7BRU|reactome:R-HSA-8849932|ensembl:ENSP00000348279|ensembl:ENSP00000367050|ensembl:ENST00000537981|ensembl:ENSP00000440874|ensembl:ENST00000540798|ensembl:ENSP00000442733|ensembl:ENST00000339997|ensembl:ENSP00000344106|ensembl:ENST00000341307|ensembl:ENSP00000340903|ensembl:ENST00000354497|ensembl:ENSP00000346492|ensembl:ENST00000356000|refseq:NP_001252519.1|refseq:NP_001252520.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nlwcgOle9rsXe2uha2//mQlB4Do9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O75947	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O15260	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P09382	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:A0FGR8	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P48047	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9NQC3	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P61619	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P30273	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-515289|uniprotkb:Q5VTW4|ensembl:ENSP00000289902	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:fcerg_human(display_long)|uniprotkb:IgE Fc receptor subunit gamma(gene name synonym)|uniprotkb:Fc-epsilon RI-gamma(gene name synonym)|uniprotkb:FCER1G(gene name)|psi-mi:FCER1G(display_short)|uniprotkb:Fc receptor gamma-chain(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_004097.1|dip:DIP-29514N|ensembl:ENSG00000158869(gene)|ensembl:ENST00000289902(transcript)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002292"(T cell differentiation involved in immune response)|go:"GO:0002431"(Fc receptor mediated stimulatory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019767"(IgE receptor activity)|go:"GO:0019863"(IgE binding)|go:"GO:0019864"(IgG binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031623"(receptor internalization)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032998"(Fc-epsilon receptor I complex)|go:"GO:0038094"(Fc-gamma receptor signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038156"(interleukin-3-mediated signaling pathway)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|interpro:IPR042340|mint:P30273|reactome:R-HSA-114604|reactome:R-HSA-202733|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0042742"(defense response to bacterium)|reactome:R-HSA-2871837|reactome:R-HSA-5621480|reactome:R-HSA-6798695|reactome:R-HSA-75892|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:sYW44kyg+jmeUmR9vWSSPdyq4N49606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P04843	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O43914	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-2214794|uniprotkb:Q6FGA5|uniprotkb:Q9UMT3|uniprotkb:A8K2X0|uniprotkb:F5H389|ensembl:ENSP00000262629	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tyobp_human(display_long)|uniprotkb:TYROBP(gene name)|psi-mi:TYROBP(display_short)|uniprotkb:DAP12(gene name synonym)|uniprotkb:KARAP(gene name synonym)|uniprotkb:DNAX-activation protein 12(gene name synonym)|uniprotkb:Killer-activating receptor-associated protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001166985.1|refseq:NP_003323.1|refseq:NP_937758.1|ensembl:ENSG00000011600(gene)|ensembl:ENST00000262629(transcript)|go:"GO:0002222"(stimulatory killer cell immunoglobulin-like receptor signaling pathway)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002274"(myeloid leukocyte activation)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0030900"(forebrain development)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0050821"(protein stabilization)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR026200|rcsb pdb:2L34|rcsb pdb:2L35|rcsb pdb:4WO1|rcsb pdb:4WOL|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-391160|reactome:R-HSA-416700|reactome:R-HSA-6798695	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:mu2fXvaw0UH/mPPCFw8kG4XJkGk9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00264	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00182	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1045193|uniprotkb:O14532|uniprotkb:O75028|uniprotkb:Q9NQ58|uniprotkb:Q3B8N1|intact:EBI-2799360|uniprotkb:A7VJG6|uniprotkb:Q53FQ0|ensembl:ENSP00000378856|uniprotkb:F8W9W4|uniprotkb:Q8WYQ7	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:leg9_human(display_long)|uniprotkb:Tumor antigen HOM-HD-21(gene name synonym)|uniprotkb:Ecalectin(gene name synonym)|uniprotkb:LGALS9(gene name)|psi-mi:LGALS9(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612397|imex:IM-28687-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_002299.2|refseq:NP_033665.1|refseq:XP_006721955.1|refseq:XP_006721958.1|ensembl:ENSG00000168961(gene)|ensembl:ENST00000395473(transcript)|go:"GO:0002519"(natural killer cell tolerance induction)|go:"GO:0005534"(galactose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007565"(female pregnancy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016936"(galactoside binding)|rcsb pdb:2ZHL|rcsb pdb:2ZHM|rcsb pdb:2ZHN|rcsb pdb:3LSD|rcsb pdb:3LSE|rcsb pdb:3NV1|rcsb pdb:3NV2|rcsb pdb:3NV3|rcsb pdb:3NV4|rcsb pdb:3WLU|rcsb pdb:3WV6|reactome:R-HSA-451927|rcsb pdb:2ZHK|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032834"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048030"(disaccharide binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070241"(positive regulation of activated T cell autonomous cell death)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0098586"(cellular response to virus)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0019899"(enzyme binding)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|rcsb pdb:2EAK|rcsb pdb:2EAL|rcsb pdb:2YY1|refseq:NP_001317092.1|refseq:XP_016880112.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:v64u66mEVbUV0bRx1LgUftidZDg9606	rigid:At3AUm8driU7O4n7HB0Lo4g9v5E	false	ha tag:n-n|strep tag:n-n|sufficient binding region:1-252,304-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q8N6C5	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-310549|uniprotkb:Q9NTC8|uniprotkb:O15070|uniprotkb:B5MEG2|ensembl:ENSP00000355010|ensembl:ENSP00000498789|uniprotkb:H9KV64	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:igsf1_human(display_long)|uniprotkb:KIAA0364(gene name synonym)|uniprotkb:IGSF1(gene name)|psi-mi:IGSF1(display_short)|uniprotkb:IGDC1(gene name synonym)|uniprotkb:PGSF2(gene name synonym)|uniprotkb:Inhibin-binding protein(gene name synonym)|uniprotkb:Immunoglobulin-like domain-containing protein 1(gene name synonym)|uniprotkb:Pituitary gland-specific factor 2(gene name synonym)|uniprotkb:p120(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001164433.1|refseq:NP_001164434.1|refseq:NP_001546.2|refseq:NP_991402.1|ensembl:ENSG00000147255(gene)|ensembl:ENST00000361420(transcript)|ensembl:ENST00000651556(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0034711"(inhibin binding)|go:"GO:0038102"(activin receptor antagonist activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001164432.1|refseq:XP_011529632.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:b/PJhWljyz87N8jQ0pNq92Xoxys9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P32970	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-18539709|uniprotkb:B4DPR8|uniprotkb:Q53XX4|uniprotkb:Q96J57|ensembl:ENSP00000245903	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:cd70_human(display_long)|uniprotkb:CD27 ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 7(gene name synonym)|uniprotkb:CD70(gene name)|psi-mi:CD70(display_short)|uniprotkb:CD27L(gene name synonym)|uniprotkb:CD27LG(gene name synonym)|uniprotkb:TNFSF7(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001243.1|refseq:NP_001317261.1|ensembl:ENSG00000125726(gene)|ensembl:ENST00000245903(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042100"(B cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042374|reactome:R-HSA-5669034|go:"GO:0042102"(positive regulation of T cell proliferation)	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:SZpubY42Y8VUFfKBGkE4Sau9BtQ9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9H0X4	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1389842|uniprotkb:Q7L416|uniprotkb:Q96FR1|uniprotkb:Q96MC7|uniprotkb:Q96S30|uniprotkb:D3DU45|ensembl:ENSP00000301678|ensembl:ENSP00000382814	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:f234a_human(display_long)|uniprotkb:FAM234A(gene name)|psi-mi:FAM234A(display_short)|uniprotkb:C16orf9(gene name synonym)|uniprotkb:ITFG3(gene name synonym)|uniprotkb:Protein ITFG3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001271426.1|refseq:NP_114428.1|refseq:XP_016879249.1|refseq:XP_016879250.1|refseq:XP_016879251.1|refseq:XP_011520993.1|refseq:XP_011520994.1|refseq:XP_005255679.1|ensembl:ENSG00000167930(gene)|ensembl:ENST00000301678(transcript)|ensembl:ENST00000399932(transcript)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|mint:Q9H0X4	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nmh0mT6DweQQVTH0zgscPL5NXRk9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:P05109	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O95816	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00560	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q15758	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9Y5Y0	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-9681535|uniprotkb:Q1HE16|uniprotkb:Q86XY9|uniprotkb:Q9NVR9|ensembl:ENSP00000355938	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:flvc1_human(display_long)|uniprotkb:FLVCR1(gene name)|psi-mi:FLVCR1(display_short)|uniprotkb:FLVCR(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_054772.1|ensembl:ENSG00000162769(gene)|ensembl:ENST00000366971(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048536"(spleen development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060323"(head morphogenesis)|go:"GO:0097037"(heme export)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q9Y5Y0|reactome:R-HSA-189451|reactome:R-HSA-917937	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bb6L2akAjb64NgdW94M2I3uMhxQ9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:O00264	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612497|imex:IM-28687-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	comment:LGALS9B/9C and  SLC25A5/A6 were also present but could not be ascribed to a single gene product.|figure legend:Fig.1B, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:8ZPLT305jV0HUWm+w0pNb+RUOdk	false	ha tag:n-n|strep tag:n-n|sufficient binding region:29-577	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26612568|imex:IM-28687-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	figure legend:Fig. 1E, Supp. Table1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/01	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	-	strep tag:c-c|ha tag:c-c	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q13568	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613340|imex:IM-28687-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	-	-	-	figure legend:Fig.4G|agonist:CpG-B dinucleotide|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:DMU1kOn9cO5+TSmtPy0Hk3esIik	false	ha tag:n-n|strep tag:n-n|mutation disrupting interaction strength:465-465	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613340|imex:IM-28687-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	figure legend:Fig.4G|agonist:CpG-B dinucleotide|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:DMU1kOn9cO5+TSmtPy0Hk3esIik	false	ha tag:n-n|strep tag:n-n|mutation disrupting interaction strength:465-465	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613151|imex:IM-28687-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	-	-	-	comment:Loss of the 28 N-terminal residues led to the accumulation of a phosphatase-sensitive, slower-migrating form of TASL but does not affect the interaction|figure legend:Figs.1F, Extd Fig. 3F, 8J|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	-	ha tag:n-n|strep tag:n-n|sufficient binding region:304-577,29-252|mutation with no effect:14-15|mutation disrupting interaction strength:465-465|mutation disrupting interaction strength:465-465|mutation with no effect:44-44|mutation with no effect:47-47	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAI6	uniprotkb:Q91W98	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-26613187|ensembl:ENSMUSP00000031367|uniprotkb:Q7TPL5	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_mouse(display_long)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:Slc15a4(gene name)|psi-mi:Slc15a4(display_short)|uniprotkb:Pht1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613227|imex:IM-28687-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	ensembl:ENSMUSG00000029416(gene)|ensembl:ENSMUST00000031367(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|reactome:R-MMU-427975|reactome:R-MMU-6798695|refseq:NP_598656.1	-	-	-	figure legend:Fig.1F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:fiAH00hHUewnHxcx/g7ZaHOBuzw10090	rigid:6XaTv3Ho2mHHAHfFZcp09Gmn6So	false	-	ha tag:n-n|strep tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N697	uniprotkb:Q13568	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613323|imex:IM-28687-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	-	-	-	figure legend:Fig.4F, 4H, Extd Fig. 10D.|agonist:CpG-B dinucleotide|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:DMU1kOn9cO5+TSmtPy0Hk3esIik	false	v5 tag:?-?|mutation disrupting interaction strength:465-465	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N697	uniprotkb:Q9HAI6	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	intact:EBI-21895669|ensembl:ENSP00000368245	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613323|imex:IM-28687-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	-	-	-	figure legend:Fig.4F, 4H, Extd Fig. 10D.|agonist:CpG-B dinucleotide|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rigid:DMU1kOn9cO5+TSmtPy0Hk3esIik	false	v5 tag:?-?|mutation disrupting interaction strength:465-465	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26656543|imex:IM-28687-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	-	-	-	comment:Loss of the 28 N-terminal residues led to the accumulation of a phosphatase-sensitive, slower-migrating form of TASL but does not affect the interaction|figure legend:Figs.4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/16	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	-	v5 tag:?-?|sufficient binding region:304-577,29-252|mutation disrupting interaction strength:465-465	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613257|imex:IM-28687-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	-	-	-	figure legend:Fig.1G, Extended fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	myc tag:?-?|sufficient binding region:1-94	ha tag:n-n|strep tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613297|imex:IM-28687-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	-	-	-	figure legend:Fig.1H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NBW4	uniprotkb:Q7L523	intact:EBI-9978316|uniprotkb:B3KXV1|uniprotkb:B7Z7D0|uniprotkb:Q0P5S0|uniprotkb:Q6MZJ8|uniprotkb:A0A0A8K8P2|ensembl:ENSP00000316596|ensembl:ENSP00000380074	intact:EBI-752376|uniprotkb:O00290|uniprotkb:Q15347|uniprotkb:B2R7L1|ensembl:ENSP00000369899	psi-mi:s38a9_human(display_long)|uniprotkb:URLC11(gene name synonym)|uniprotkb:Up-regulated in lung cancer 11(gene name synonym)|uniprotkb:SLC38A9(gene name)|psi-mi:SLC38A9(display_short)|uniprotkb:Solute carrier family 38 member 9(gene name synonym)	psi-mi:rraga_human(display_long)|uniprotkb:Adenovirus E3 14.7 kDa-interacting protein 1(gene name synonym)|uniprotkb:FIP-1(gene name synonym)|uniprotkb:RRAGA(gene name)|psi-mi:RRAGA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613317|imex:IM-28687-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001245215.1|refseq:NP_001245216.1|refseq:NP_775785.2|refseq:XP_006714600.1|refseq:XP_006714601.1|refseq:XP_006714602.1|refseq:XP_011541475.1|refseq:XP_011541476.1|dip:DIP-61480N|ensembl:ENSG00000177058(gene)|ensembl:ENST00000318672(transcript)|ensembl:ENST00000396865(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013057(Amino acid transporter, transmembrane)|rcsb pdb:6WJ2|rcsb pdb:6WJ3|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	refseq:NP_006561.1|dip:DIP-37516N|rcsb pdb:6S6A|ensembl:ENSG00000155876(gene)|ensembl:ENST00000380527(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:5X6V|rcsb pdb:6CES|rcsb pdb:6EHR|rcsb pdb:6NZD|rcsb pdb:6S6D|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|rcsb pdb:6ULG|rcsb pdb:6WJ2|rcsb pdb:6WJ3|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8866654|reactome:R-HSA-8943724|reactome:R-HSA-9639288	-	-	-	figure legend:Fig.1H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:wB8tjYMegNixZ5yElpNUNChR46A9606	rogid:1BxTVycwXop9+lViwQU5TyK/tlI9606	rigid:undw8OdHJmYfQTsUqTKzuj1E7Kg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613507|imex:IM-28687-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	-	-	-	figure legend:Extended Fig.3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-kbm7)|taxid:9606(KBM-7 chronic myelogenous leukemia cell)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	-	ha tag:n-n|strep tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HAI6	uniprotkb:Q8N697	intact:EBI-21895669|ensembl:ENSP00000368245	intact:EBI-4319594|uniprotkb:A6H8Y9|uniprotkb:B3KTK1|uniprotkb:Q71M34|uniprotkb:Q7Z5F8|uniprotkb:Q8TAH0|ensembl:ENSP00000266771	psi-mi:tasl_human(display_long)|uniprotkb:TASL(gene name)|psi-mi:TASL(display_short)|uniprotkb:CXorf21(gene name synonym)	psi-mi:s15a4_human(display_long)|uniprotkb:SLC15A4(gene name)|psi-mi:SLC15A4(display_short)|uniprotkb:PHT1(gene name synonym)|uniprotkb:PTR4(gene name synonym)|uniprotkb:Peptide transporter 4(gene name synonym)|uniprotkb:Peptide/histidine transporter 1(gene name synonym)|uniprotkb:FP12591(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Heinz et al. (2020)	pubmed:32433612|imex:IM-28687	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26613532|imex:IM-28687-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079435.1|ensembl:ENSG00000120280(gene)|ensembl:ENST00000378962(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|interpro:IPR027869	refseq:NP_663623.1|ensembl:ENSG00000139370(gene)|ensembl:ENST00000266771(transcript)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0015647"(peptidoglycan transmembrane transporter activity)|go:"GO:0015817"(histidine transport)|go:"GO:0015835"(peptidoglycan transport)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033023"(mast cell homeostasis)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048302"(regulation of isotype switching to IgG isotypes)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070430"(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0089708"(L-histidine transmembrane export from vacuole)|go:"GO:0140206"(dipeptide import across plasma membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR018456|interpro:IPR036259|mint:Q8N697|reactome:R-HSA-427975|reactome:R-HSA-6798695|go:"GO:0036020"(endolysosome membrane)|dip:DIP-60839N	go:"GO:0036020"(endolysosome membrane)	-	-	figure legend:Extd Fig. 4D|comment:Loss of the N-terminal 28 residues of  SLC15A4 resulted in colocalization at the plasma membrane.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2021/01/29	2021/02/02	rogid:bTs5YdTrKZvv1YQxPffYBF/5OqM9606	rogid:vu4B0G9993k3P93S7sN31ky7l889606	rigid:WEbWIF1QGd3Hu7AwKLoef7l8VVg	false	green fluorescent protein tag:?-?	ha tag:n-n|strep tag:n-n|sufficient binding region:304-577|mutation disrupting interaction strength:465-465	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)