#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B3DLA5	uniprotkb:B3DLA5	intact:EBI-26584156|ensembl:ENSXETP00000014090|uniprotkb:F6Q0L0|uniprotkb:F7BAI1	intact:EBI-26584156|ensembl:ENSXETP00000014090|uniprotkb:F6Q0L0|uniprotkb:F7BAI1	psi-mi:b3dla5_xentr(display_long)|uniprotkb:panx1(gene name)|psi-mi:panx1(display_short)|uniprotkb:LOC100170473(gene name synonym)|uniprotkb:PANX(gene name synonym)	psi-mi:b3dla5_xentr(display_long)|uniprotkb:panx1(gene name)|psi-mi:panx1(display_short)|uniprotkb:LOC100170473(gene name synonym)|uniprotkb:PANX(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Deng et al. (2020)	pubmed:32231289|imex:IM-28718	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26584153|imex:IM-28718-1|wwpdb:6UZY|emdb:EMD-20964	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSXETG00000006428(gene)|ensembl:ENSXETT00000014090(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0042802"(identical protein binding)|interpro:IPR000990(Innexin)|interpro:IPR039099|rcsb pdb:6UZY|rcsb pdb:6VD7|refseq:NP_001123728.1	ensembl:ENSXETG00000006428(gene)|ensembl:ENSXETT00000014090(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0042802"(identical protein binding)|interpro:IPR000990(Innexin)|interpro:IPR039099|rcsb pdb:6UZY|rcsb pdb:6VD7|refseq:NP_001123728.1	-	-	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)")	-	2021/01/02	2021/01/30	rogid:Xhy065bTIFRCwLZKaYqAN8P14VE8364	rogid:Xhy065bTIFRCwLZKaYqAN8P14VE8364	rigid:afwOMjQixPgFTC112OMAaRc0ECU	false	-	-	7	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q96RD7-1	uniprotkb:Q96RD7-1	intact:EBI-25747443|ensembl:ENSP00000227638	intact:EBI-25747443|ensembl:ENSP00000227638	psi-mi:q96rd7-1(display_long)|uniprotkb:PANX1(gene name)|psi-mi:PANX1(display_short)|uniprotkb:MRS1(gene name synonym)|uniprotkb:UNQ2529/PRO6028(orf name)	psi-mi:q96rd7-1(display_long)|uniprotkb:PANX1(gene name)|psi-mi:PANX1(display_short)|uniprotkb:MRS1(gene name synonym)|uniprotkb:UNQ2529/PRO6028(orf name)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Deng et al. (2020)	pubmed:32231289|imex:IM-28718	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26609836|imex:IM-28718-3|emdb:EMD-21071|wwpdb:6V6D	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110218(gene)|ensembl:ENST00000227638(transcript)|intact:EBI-7037612(isoform-parent)	ensembl:ENSG00000110218(gene)|ensembl:ENST00000227638(transcript)|intact:EBI-7037612(isoform-parent)	-	-	-	figure legend:Fig. 4, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)")	-	2021/01/02	2021/02/01	rogid:4RTDyFKsL6d8oA8AsJT285+Yz1M9606	rogid:4RTDyFKsL6d8oA8AsJT285+Yz1M9606	rigid:XbT0TCLT7ibvg1PSEs27zXzi8nA	false	-	-	7	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:B3DLA5	uniprotkb:B3DLA5	intact:EBI-26584156|ensembl:ENSXETP00000014090|uniprotkb:F6Q0L0|uniprotkb:F7BAI1	intact:EBI-26584156|ensembl:ENSXETP00000014090|uniprotkb:F6Q0L0|uniprotkb:F7BAI1	psi-mi:b3dla5_xentr(display_long)|uniprotkb:panx1(gene name)|psi-mi:panx1(display_short)|uniprotkb:LOC100170473(gene name synonym)|uniprotkb:PANX(gene name synonym)	psi-mi:b3dla5_xentr(display_long)|uniprotkb:panx1(gene name)|psi-mi:panx1(display_short)|uniprotkb:LOC100170473(gene name synonym)|uniprotkb:PANX(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2020)	pubmed:32231289|imex:IM-28718	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26609854|imex:IM-28718-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSXETG00000006428(gene)|ensembl:ENSXETT00000014090(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0042802"(identical protein binding)|interpro:IPR000990(Innexin)|interpro:IPR039099|rcsb pdb:6UZY|rcsb pdb:6VD7|refseq:NP_001123728.1	ensembl:ENSXETG00000006428(gene)|ensembl:ENSXETT00000014090(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006812"(cation transport)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0042802"(identical protein binding)|interpro:IPR000990(Innexin)|interpro:IPR039099|rcsb pdb:6UZY|rcsb pdb:6VD7|refseq:NP_001123728.1	emdb:EMD-20964(see-also)|wwpdb:6UZY(see-also)	-	-	figure legend:Extended Data Fig. 5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)")	-	2021/01/02	2021/01/30	rogid:Xhy065bTIFRCwLZKaYqAN8P14VE8364	rogid:Xhy065bTIFRCwLZKaYqAN8P14VE8364	rigid:afwOMjQixPgFTC112OMAaRc0ECU	false	-	-	7	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q96RD7-1	uniprotkb:Q96RD7-1	intact:EBI-25747443|ensembl:ENSP00000227638	intact:EBI-25747443|ensembl:ENSP00000227638	psi-mi:q96rd7-1(display_long)|uniprotkb:PANX1(gene name)|psi-mi:PANX1(display_short)|uniprotkb:MRS1(gene name synonym)|uniprotkb:UNQ2529/PRO6028(orf name)	psi-mi:q96rd7-1(display_long)|uniprotkb:PANX1(gene name)|psi-mi:PANX1(display_short)|uniprotkb:MRS1(gene name synonym)|uniprotkb:UNQ2529/PRO6028(orf name)	psi-mi:"MI:0030"(cross-linking study)	Deng et al. (2020)	pubmed:32231289|imex:IM-28718	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26609866|imex:IM-28718-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110218(gene)|ensembl:ENST00000227638(transcript)|intact:EBI-7037612(isoform-parent)	ensembl:ENSG00000110218(gene)|ensembl:ENST00000227638(transcript)|intact:EBI-7037612(isoform-parent)	emdb:EMD-21071(see-also)|wwpdb:6V6D(see-also)	-	-	figure legend:Extended Data Fig. 5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)")	-	2021/01/02	2021/02/01	rogid:4RTDyFKsL6d8oA8AsJT285+Yz1M9606	rogid:4RTDyFKsL6d8oA8AsJT285+Yz1M9606	rigid:XbT0TCLT7ibvg1PSEs27zXzi8nA	false	-	-	7	0	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)