#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9VS51	uniprotkb:Q9VND8	intact:EBI-180370|uniprotkb:Q8T0M3|ensemblmetazoa:FBpp0076591|ensemblmetazoa:FBpp0304978|ensemblmetazoa:FBpp0304979	intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343	psi-mi:q9vs51_drome(display_long)|uniprotkb:Cln7(gene name)|psi-mi:Cln7(display_short)|uniprotkb:Dmel\CG8596(gene name synonym)|uniprotkb:cln7(gene name synonym)|uniprotkb:Dmel_CG8596(orf name)|uniprotkb:CG8596(orf name)|uniprotkb:CLN7(gene name synonym)	psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Connolly et al. (2019)	pubmed:31666534|imex:IM-28727	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26620090|imex:IM-28727-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_648107.3|flybase:FBgn0035767|refseq:NP_001261508.1|refseq:NP_001261509.1|ensemblmetazoa:FBgn0035767(gene)|ensemblmetazoa:FBtr0076881(transcript)|ensemblmetazoa:FBtr0332732(transcript)|ensemblmetazoa:FBtr0332733(transcript)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259	refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity)	-	-	-	figure legend:f6d|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2021/02/11	2021/02/11	rogid:BFpJ2gdPZ0GIhl4unPwZxUIdAq87227	rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227	rigid:bsnEpM+NY+vavmTaBfMSTMD6HGc	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9VS51	uniprotkb:Q9VND8	intact:EBI-180370|uniprotkb:Q8T0M3|ensemblmetazoa:FBpp0076591|ensemblmetazoa:FBpp0304978|ensemblmetazoa:FBpp0304979	intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343	psi-mi:q9vs51_drome(display_long)|uniprotkb:Cln7(gene name)|psi-mi:Cln7(display_short)|uniprotkb:Dmel\CG8596(gene name synonym)|uniprotkb:cln7(gene name synonym)|uniprotkb:Dmel_CG8596(orf name)|uniprotkb:CG8596(orf name)|uniprotkb:CLN7(gene name synonym)	psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Connolly et al. (2019)	pubmed:31666534|imex:IM-28727	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26620112|imex:IM-28727-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_648107.3|flybase:FBgn0035767|refseq:NP_001261508.1|refseq:NP_001261509.1|ensemblmetazoa:FBgn0035767(gene)|ensemblmetazoa:FBtr0076881(transcript)|ensemblmetazoa:FBtr0332732(transcript)|ensemblmetazoa:FBtr0332733(transcript)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259	refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity)	-	-	-	figure legend:f6d|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2021/02/11	2021/02/11	rogid:BFpJ2gdPZ0GIhl4unPwZxUIdAq87227	rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227	rigid:bsnEpM+NY+vavmTaBfMSTMD6HGc	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9VND8	uniprotkb:Q9VS51	intact:EBI-4372932|uniprotkb:Q0KIB7|ensemblmetazoa:FBpp0078342|ensemblmetazoa:FBpp0078343	intact:EBI-180370|uniprotkb:Q8T0M3|ensemblmetazoa:FBpp0076591|ensemblmetazoa:FBpp0304978|ensemblmetazoa:FBpp0304979	psi-mi:rheb_drome(display_long)|uniprotkb:Rheb(gene name)|psi-mi:Rheb(display_short)|uniprotkb:CG1081(orf name)	psi-mi:q9vs51_drome(display_long)|uniprotkb:Cln7(gene name)|psi-mi:Cln7(display_short)|uniprotkb:Dmel\CG8596(gene name synonym)|uniprotkb:cln7(gene name synonym)|uniprotkb:Dmel_CG8596(orf name)|uniprotkb:CG8596(orf name)|uniprotkb:CLN7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Connolly et al. (2019)	pubmed:31666534|imex:IM-28727	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-26620128|imex:IM-28727-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_730950.2|refseq:NP_730951.2|flybase:FBgn0041191|dip:DIP-60269N|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007430"(terminal branching, open tracheal system)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019003"(GDP binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045176"(apical protein localization)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0090070"(positive regulation of ribosome biogenesis)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1903940"(negative regulation of TORC2 signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904503"(negative regulation of lipophagy)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DME-110523|reactome:R-DME-1632852|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-380972|reactome:R-DME-5628897|reactome:R-DME-8943724|reactome:R-DME-9639288|ensemblmetazoa:FBgn0041191(gene)|ensemblmetazoa:FBtr0078693(transcript)|ensemblmetazoa:FBtr0078694(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003924"(GTPase activity)	refseq:NP_648107.3|flybase:FBgn0035767|refseq:NP_001261508.1|refseq:NP_001261509.1|ensemblmetazoa:FBgn0035767(gene)|ensemblmetazoa:FBtr0076881(transcript)|ensemblmetazoa:FBtr0332732(transcript)|ensemblmetazoa:FBtr0332733(transcript)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259	-	-	-	figure legend:sf2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2021/02/11	2021/02/11	rogid:a8qIHNMXIA6UhaQLWTnjsAvW8OY7227	rogid:BFpJ2gdPZ0GIhl4unPwZxUIdAq87227	rigid:bsnEpM+NY+vavmTaBfMSTMD6HGc	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)