#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y282 uniprotkb:Q9P0N8 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-10317612|uniprotkb:Q96B78|uniprotkb:A6NP10|uniprotkb:Q5H785|uniprotkb:Q8N5A3|ensembl:ENSP00000215555|ensembl:ENSP00000471536 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:marh2_human(display_long)|uniprotkb:MARCHF2(gene name)|psi-mi:MARCHF2(display_short)|uniprotkb:MARCH2(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 2(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein II(gene name synonym)|uniprotkb:RING finger protein 172(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF2(gene name synonym)|uniprotkb:RNF172(gene name synonym)|uniprotkb:HSPC240(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-27120747|imex:IM-29332-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_001005415.1|refseq:NP_001005416.1|refseq:NP_057580.3|refseq:XP_006722826.1|ensembl:ENSG00000099785(gene)|ensembl:ENST00000215555(transcript)|ensembl:ENST00000602117(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_016882342.1 - - - figure legend:Fig. 1A/B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/04 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:gG4r8IvxoKpud6zzQ5V776QEewQ9606 rigid:WfBK8uPkpxhBYxxMMTsjRou+TQI false ha tag:?-?|ubiquitinylated lysine:8-8 bira tag:?-?|mutation decreasing interaction strength:64-64,67-67|flag tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y282 uniprotkb:Q9P0N8 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-10317612|uniprotkb:Q96B78|uniprotkb:A6NP10|uniprotkb:Q5H785|uniprotkb:Q8N5A3|ensembl:ENSP00000215555|ensembl:ENSP00000471536 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:marh2_human(display_long)|uniprotkb:MARCHF2(gene name)|psi-mi:MARCHF2(display_short)|uniprotkb:MARCH2(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 2(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein II(gene name synonym)|uniprotkb:RING finger protein 172(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF2(gene name synonym)|uniprotkb:RNF172(gene name synonym)|uniprotkb:HSPC240(orf name) psi-mi:"MI:0663"(confocal microscopy) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-27120770|imex:IM-29332-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_001005415.1|refseq:NP_001005416.1|refseq:NP_057580.3|refseq:XP_006722826.1|ensembl:ENSG00000099785(gene)|ensembl:ENST00000215555(transcript)|ensembl:ENST00000602117(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_016882342.1 - - - figure legend:Fig. 1C, 5B, 5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/04 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:gG4r8IvxoKpud6zzQ5V776QEewQ9606 rigid:WfBK8uPkpxhBYxxMMTsjRou+TQI false ha tag:?-?|sufficient binding region:1-362|mutation with no effect:8-8,6-6 mutation with no effect:64-64,67-67|flag tag:?-? - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9Y282 uniprotkb:Q9P0N8 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-10317612|uniprotkb:Q96B78|uniprotkb:A6NP10|uniprotkb:Q5H785|uniprotkb:Q8N5A3|ensembl:ENSP00000215555|ensembl:ENSP00000471536 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:marh2_human(display_long)|uniprotkb:MARCHF2(gene name)|psi-mi:MARCHF2(display_short)|uniprotkb:MARCH2(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 2(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein II(gene name synonym)|uniprotkb:RING finger protein 172(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF2(gene name synonym)|uniprotkb:RNF172(gene name synonym)|uniprotkb:HSPC240(orf name) psi-mi:"MI:0663"(confocal microscopy) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-27120789|imex:IM-29332-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_001005415.1|refseq:NP_001005416.1|refseq:NP_057580.3|refseq:XP_006722826.1|ensembl:ENSG00000099785(gene)|ensembl:ENST00000215555(transcript)|ensembl:ENST00000602117(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_016882342.1 go:"GO:0005886"(plasma membrane) - - figure legend:Fig. 2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/04 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:gG4r8IvxoKpud6zzQ5V776QEewQ9606 rigid:WfBK8uPkpxhBYxxMMTsjRou+TQI false - mutation causing an interaction:64-64,67-67|flag tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9Y282 uniprotkb:Q96RQ1 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-4403663|uniprotkb:A6NHH6|uniprotkb:Q53GY2|uniprotkb:Q8N2Q9|uniprotkb:Q9BVV9|uniprotkb:Q9NZA3|ensembl:ENSP00000353270 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:ergi2_human(display_long)|uniprotkb:ERGIC2(gene name)|psi-mi:ERGIC2(display_short)|uniprotkb:ERV41(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:CDA14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27120818|imex:IM-29332-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_057654.2|ensembl:ENSG00000087502(gene)|ensembl:ENST00000360150(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542 - - - figure legend:Supp. Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/04 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:+T1RODVKNyboKSh3evzH0SZUm7s9606 rigid:OhZ7b01/r2AiatxfAp16kl0RWno false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y282 uniprotkb:Q9Y282 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121248|imex:IM-29332-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:sXWB61DSHczeUCDwtap4KaJ35QE false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96RQ1 uniprotkb:Q9Y282 intact:EBI-4403663|uniprotkb:A6NHH6|uniprotkb:Q53GY2|uniprotkb:Q8N2Q9|uniprotkb:Q9BVV9|uniprotkb:Q9NZA3|ensembl:ENSP00000353270 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:ergi2_human(display_long)|uniprotkb:ERGIC2(gene name)|psi-mi:ERGIC2(display_short)|uniprotkb:ERV41(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:CDA14(orf name) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121256|imex:IM-29332-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057654.2|ensembl:ENSG00000087502(gene)|ensembl:ENST00000360150(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:+T1RODVKNyboKSh3evzH0SZUm7s9606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:OhZ7b01/r2AiatxfAp16kl0RWno false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q969X5 uniprotkb:Q9Y282 intact:EBI-781527|uniprotkb:Q9H0L0|uniprotkb:Q9H2J2|uniprotkb:Q9ULN9|ensembl:ENSP00000377374 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:ergi1_human(display_long)|uniprotkb:ER-Golgi intermediate compartment 32 kDa protein(gene name synonym)|uniprotkb:ERGIC1(gene name)|psi-mi:ERGIC1(display_short)|uniprotkb:KIAA1181(gene name synonym)|uniprotkb:HT034(orf name)|uniprotkb:ERGIC32(gene name synonym) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121264|imex:IM-29332-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006714955.1|refseq:NP_001026881.1|ensembl:ENSG00000113719(gene)|ensembl:ENST00000393784(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Supp. Fig. 1B|comment:Weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:UbuPGmvwVwrwg/LT5oAn9pLs5Hw9606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:IKts/UNnUJxZB+Bnw7KCK/AhSHE false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P0N8 uniprotkb:Q9Y282 intact:EBI-10317612|uniprotkb:Q96B78|uniprotkb:A6NP10|uniprotkb:Q5H785|uniprotkb:Q8N5A3|ensembl:ENSP00000215555|ensembl:ENSP00000471536 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:marh2_human(display_long)|uniprotkb:MARCHF2(gene name)|psi-mi:MARCHF2(display_short)|uniprotkb:MARCH2(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 2(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein II(gene name synonym)|uniprotkb:RING finger protein 172(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF2(gene name synonym)|uniprotkb:RNF172(gene name synonym)|uniprotkb:HSPC240(orf name) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121273|imex:IM-29332-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005415.1|refseq:NP_001005416.1|refseq:NP_057580.3|refseq:XP_006722826.1|ensembl:ENSG00000099785(gene)|ensembl:ENST00000215555(transcript)|ensembl:ENST00000602117(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_016882342.1 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:gG4r8IvxoKpud6zzQ5V776QEewQ9606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:WfBK8uPkpxhBYxxMMTsjRou+TQI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y282 uniprotkb:Q9P0N8 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-10317612|uniprotkb:Q96B78|uniprotkb:A6NP10|uniprotkb:Q5H785|uniprotkb:Q8N5A3|ensembl:ENSP00000215555|ensembl:ENSP00000471536 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:marh2_human(display_long)|uniprotkb:MARCHF2(gene name)|psi-mi:MARCHF2(display_short)|uniprotkb:MARCH2(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 2(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein II(gene name synonym)|uniprotkb:RING finger protein 172(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF2(gene name synonym)|uniprotkb:RNF172(gene name synonym)|uniprotkb:HSPC240(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121298|imex:IM-29332-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_001005415.1|refseq:NP_001005416.1|refseq:NP_057580.3|refseq:XP_006722826.1|ensembl:ENSG00000099785(gene)|ensembl:ENST00000215555(transcript)|ensembl:ENST00000602117(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_016882342.1 - - - figure legend:Fig. 3B-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:gG4r8IvxoKpud6zzQ5V776QEewQ9606 rigid:WfBK8uPkpxhBYxxMMTsjRou+TQI false ha tag:?-?|mutation with no effect:6-6,8-8 flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y282 uniprotkb:P01009 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121361|imex:IM-29332-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 - - - figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rigid:eDYhd/D/D6+A6M8bhoYWsE5rPNY false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49257 uniprotkb:P01009 intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym) psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121370|imex:IM-29332-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 - - - figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rigid:JEewfa/aWS+u9SGg8nMzpmbmT6c false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y282 uniprotkb:P00738 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 intact:EBI-1220767|uniprotkb:P00737|uniprotkb:Q0VAC4|uniprotkb:Q2PP15|uniprotkb:Q3B7J0|uniprotkb:Q6LBY9|uniprotkb:B0AZL5|uniprotkb:Q9UC67|uniprotkb:Q0VAC5|ensembl:ENSP00000348170 psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:hpt_human(display_long)|uniprotkb:HP(gene name)|psi-mi:HP(display_short)|uniprotkb:Zonulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121378|imex:IM-29332-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 refseq:NP_001119574.1|refseq:NP_005134.1|refseq:NP_001305067.1|ensembl:ENSG00000257017(gene)|ensembl:ENST00000355906(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031638"(zymogen activation)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR008292(Haptoglobin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR035976|interpro:IPR043504|mint:P00738|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:5HU6|rcsb pdb:6TB2|reactome:R-HSA-2168880|go:"GO:0072562"(blood microparticle)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:2000296"(negative regulation of hydrogen peroxide catabolic process)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|reactome:R-HSA-6798695 - - - figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rogid:IsI1hIXfhsW0goXPHsoADxl7V5g9606 rigid:b2bLwV6yHVKxpsEFPco5TUqEEs4 false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P01009 uniprotkb:Q9Y282 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121394|imex:IM-29332-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:eDYhd/D/D6+A6M8bhoYWsE5rPNY false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P00738 uniprotkb:Q9Y282 intact:EBI-1220767|uniprotkb:P00737|uniprotkb:Q0VAC4|uniprotkb:Q2PP15|uniprotkb:Q3B7J0|uniprotkb:Q6LBY9|uniprotkb:B0AZL5|uniprotkb:Q9UC67|uniprotkb:Q0VAC5|ensembl:ENSP00000348170 intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358 psi-mi:hpt_human(display_long)|uniprotkb:HP(gene name)|psi-mi:HP(display_short)|uniprotkb:Zonulin(gene name synonym) psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yoo et al. (2019) pubmed:31142615|imex:IM-29332 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27121403|imex:IM-29332-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001119574.1|refseq:NP_005134.1|refseq:NP_001305067.1|ensembl:ENSG00000257017(gene)|ensembl:ENST00000355906(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031638"(zymogen activation)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR008292(Haptoglobin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR035976|interpro:IPR043504|mint:P00738|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:5HU6|rcsb pdb:6TB2|reactome:R-HSA-2168880|go:"GO:0072562"(blood microparticle)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:2000296"(negative regulation of hydrogen peroxide catabolic process)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|reactome:R-HSA-6798695 refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2021/11/04 2021/11/05 rogid:IsI1hIXfhsW0goXPHsoADxl7V5g9606 rogid:LllzE6k0eaM1uUJGjkieiPARw149606 rigid:b2bLwV6yHVKxpsEFPco5TUqEEs4 false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)