#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H1Y3	uniprotkb:Q01726	intact:EBI-21871627|uniprotkb:Q8IX08|uniprotkb:Q9Y344|ensembl:ENSP00000355512	intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011	psi-mi:opn3_human(display_long)|uniprotkb:Encephalopsin(gene name synonym)|uniprotkb:Panopsin(gene name synonym)|uniprotkb:OPN3(gene name)|psi-mi:OPN3(display_short)|uniprotkb:ECPN(gene name synonym)	psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ozdeslik et al. (2019)	pubmed:31097585|imex:IM-28998	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26988170|imex:IM-28998-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055137.2|ensembl:ENSG00000054277(gene)|ensembl:ENST00000366554(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009583"(detection of light stimulus)|go:"GO:0009637"(response to blue light)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-HSA-418594|reactome:R-HSA-419771|go:"GO:0005737"(cytoplasm)	refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821	-	-	-	figure legend:Fig. 7A, Supp. figure 5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/05/18	2021/06/08	rogid:A7fE2XTvp2VcWNKd7/gtaIBs3409606	rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606	rigid:e6np2TxKKNVJajllSzI3tkEiR68	false	flag tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H1Y3	uniprotkb:Q01726	intact:EBI-21871627|uniprotkb:Q8IX08|uniprotkb:Q9Y344|ensembl:ENSP00000355512	intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011	psi-mi:opn3_human(display_long)|uniprotkb:Encephalopsin(gene name synonym)|uniprotkb:Panopsin(gene name synonym)|uniprotkb:OPN3(gene name)|psi-mi:OPN3(display_short)|uniprotkb:ECPN(gene name synonym)	psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ozdeslik et al. (2019)	pubmed:31097585|imex:IM-28998	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26988178|imex:IM-28998-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055137.2|ensembl:ENSG00000054277(gene)|ensembl:ENST00000366554(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009583"(detection of light stimulus)|go:"GO:0009637"(response to blue light)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-HSA-418594|reactome:R-HSA-419771|go:"GO:0005737"(cytoplasm)	refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821	-	-	-	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/05/18	2021/06/08	rogid:A7fE2XTvp2VcWNKd7/gtaIBs3409606	rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606	rigid:e6np2TxKKNVJajllSzI3tkEiR68	false	flag tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H1Y3	uniprotkb:Q01726	intact:EBI-21871627|uniprotkb:Q8IX08|uniprotkb:Q9Y344|ensembl:ENSP00000355512	intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011	psi-mi:opn3_human(display_long)|uniprotkb:Encephalopsin(gene name synonym)|uniprotkb:Panopsin(gene name synonym)|uniprotkb:OPN3(gene name)|psi-mi:OPN3(display_short)|uniprotkb:ECPN(gene name synonym)	psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ozdeslik et al. (2019)	pubmed:31097585|imex:IM-28998	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26988195|imex:IM-28998-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055137.2|ensembl:ENSG00000054277(gene)|ensembl:ENST00000366554(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009583"(detection of light stimulus)|go:"GO:0009637"(response to blue light)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-HSA-418594|reactome:R-HSA-419771|go:"GO:0005737"(cytoplasm)	refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanocyte)|taxid:9606(Homo sapiens melanocyte)	-	2021/05/18	2021/06/08	rogid:A7fE2XTvp2VcWNKd7/gtaIBs3409606	rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606	rigid:e6np2TxKKNVJajllSzI3tkEiR68	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H1Y3	uniprotkb:Q01726	intact:EBI-21871627|uniprotkb:Q8IX08|uniprotkb:Q9Y344|ensembl:ENSP00000355512	intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011	psi-mi:opn3_human(display_long)|uniprotkb:Encephalopsin(gene name synonym)|uniprotkb:Panopsin(gene name synonym)|uniprotkb:OPN3(gene name)|psi-mi:OPN3(display_short)|uniprotkb:ECPN(gene name synonym)	psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ozdeslik et al. (2019)	pubmed:31097585|imex:IM-28998	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26988209|imex:IM-28998-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055137.2|ensembl:ENSG00000054277(gene)|ensembl:ENST00000366554(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009583"(detection of light stimulus)|go:"GO:0009637"(response to blue light)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-HSA-418594|reactome:R-HSA-419771|go:"GO:0005737"(cytoplasm)	refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:Fig. 6A, Supp Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/05/18	2021/06/08	rogid:A7fE2XTvp2VcWNKd7/gtaIBs3409606	rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606	rigid:e6np2TxKKNVJajllSzI3tkEiR68	false	yellow fluorescent protein tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:Q9H1Y3	uniprotkb:Q01726	intact:EBI-21871627|uniprotkb:Q8IX08|uniprotkb:Q9Y344|ensembl:ENSP00000355512	intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011	psi-mi:opn3_human(display_long)|uniprotkb:Encephalopsin(gene name synonym)|uniprotkb:Panopsin(gene name synonym)|uniprotkb:OPN3(gene name)|psi-mi:OPN3(display_short)|uniprotkb:ECPN(gene name synonym)	psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Ozdeslik et al. (2019)	pubmed:31097585|imex:IM-28998	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26988389|imex:IM-28998-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055137.2|ensembl:ENSG00000054277(gene)|ensembl:ENST00000366554(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005503"(all-trans retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009583"(detection of light stimulus)|go:"GO:0009637"(response to blue light)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-HSA-418594|reactome:R-HSA-419771|go:"GO:0005737"(cytoplasm)	refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821	go:"GO:0043229"(intracellular organelle)|go:"GO:0005886"(plasma membrane)	-	-	figure legend:Fig. 6D, Supp. Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-melanocyte)|taxid:9606(Homo sapiens melanocyte)	-	2021/05/18	2021/06/08	rogid:A7fE2XTvp2VcWNKd7/gtaIBs3409606	rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606	rigid:e6np2TxKKNVJajllSzI3tkEiR68	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)