#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NWB6 uniprotkb:Q5FBB7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-989069|ensembl:ENSP00000263753|ensembl:ENSP00000414129|uniprotkb:Q5FBB4|uniprotkb:Q5FBB5|uniprotkb:Q5FBB6|uniprotkb:Q5FBB8|uniprotkb:Q8N579|uniprotkb:Q8WVL0|uniprotkb:Q9BVA8|uniprotkb:Q9H275|uniprotkb:Q588H5|intact:EBI-2555999 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:sgo1_human(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000129810(gene)|ensembl:ENST00000263753(transcript)|ensembl:ENST00000421451(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071962"(mitotic sister chromatid cohesion, centromeric)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal)|interpro:IPR028321|interpro:IPR038889|mint:Q5FBB7|rcsb pdb:3FGA|rcsb pdb:3Q6S|rcsb pdb:4A0I|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001012409.1|refseq:NP_001012410.1|refseq:NP_001012411.1|refseq:NP_001012412.1|refseq:NP_001012413.1|refseq:NP_001186180.1|refseq:NP_001186181.1|refseq:NP_001186182.1|refseq:NP_001186183.1|refseq:NP_001186184.1|refseq:NP_001186185.1|refseq:NP_001186186.1|refseq:NP_612493.1|refseq:XP_011531675.1|refseq:XP_011531677.1|refseq:XP_011531678.1|refseq:XP_011531679.1|dip:DIP-36614N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:rTa6IoM9PWfd6qOccSMZy1o0bBU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q99633 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2798416|uniprotkb:Q5T9P9|uniprotkb:Q9BUI9|ensembl:ENSP00000367835 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:prp18_human(display_long)|uniprotkb:HPRP18(gene name synonym)|uniprotkb:PRP18 homolog(gene name synonym)|uniprotkb:PRPF18(gene name)|psi-mi:PRPF18(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_003666.1|ensembl:ENSG00000165630(gene)|ensembl:ENST00000378572(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071021"(U2-type post-spliceosomal complex)|go:"GO:0071048"|interpro:IPR004098(Prp18)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR036285|interpro:IPR039979|rcsb pdb:2DK4 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:FBlmzuM1sm+SDRAGAEwsqT58T349606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8NEY8 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9P016 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2795681|uniprotkb:Q567Q2|uniprotkb:Q9H3L4|uniprotkb:Q9HC20|ensembl:ENSP00000341657|ensembl:ENSP00000376373|ensembl:ENSP00000376374 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:thyn1_human(display_long)|uniprotkb:THYN1(gene name)|psi-mi:THYN1(display_short)|uniprotkb:THY28(gene name synonym)|uniprotkb:Thymocyte protein Thy28(gene name synonym)|uniprotkb:HSPC144(orf name)|uniprotkb:MDS012(orf name)|uniprotkb:My0054(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001032381.1|refseq:NP_001032382.1|refseq:NP_054893.1|refseq:NP_954994.1|refseq:NP_954995.1|mint:Q9P016|rcsb pdb:3EOP|rcsb pdb:5J3E|interpro:IPR015947(PUA-like)|ensembl:ENSG00000151500(gene)|ensembl:ENST00000341541(transcript)|ensembl:ENST00000392594(transcript)|ensembl:ENST00000392595(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR002740(Protein of unknown function DUF55) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:a/mbijtJl0FzO3ZmXwBTXp0uTyU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:C9JI46 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886966|ensembl:ENSP00000371659 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:c9ji46_human(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short)|uniprotkb:MLR1(gene name synonym)|uniprotkb:hCG_1660774(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000178177(gene)|ensembl:ENST00000382224(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:MjyD0+eCUk2Z4kCvL4l+Gl5goK09606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F8W1I9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886946|ensembl:ENSP00000446959 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f8w1i9_human(display_long)|uniprotkb:ACAD10(gene name)|psi-mi:ACAD10(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000111271(gene)|ensembl:ENST00000549590(transcript)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0016787"(hydrolase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011945(Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal)|interpro:IPR023198|interpro:IPR023214|interpro:IPR036412|interpro:IPR037069|interpro:IPR041492|interpro:IPR041726 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:4586jmt3U+vTGSBJaHAUmriKsf09606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BTA9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-749118|intact:EBI-947208|uniprotkb:C9JBT9|uniprotkb:Q5JU75|uniprotkb:Q5JU77|uniprotkb:Q53EN9|uniprotkb:Q5VXK0|uniprotkb:Q5VXK2|uniprotkb:Q8TCK1|uniprotkb:Q96DP3|uniprotkb:Q96FW6|uniprotkb:Q96JI3|uniprotkb:A8K2A9|intact:EBI-1105304|uniprotkb:D3DRW5|uniprotkb:D3DRW6|uniprotkb:D3DRW7|ensembl:ENSP00000346986 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:wac_human(display_long)|uniprotkb:WAC(gene name)|psi-mi:WAC(display_short)|uniprotkb:KIAA1844(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:XP_011517793.1|refseq:NP_057712.2|refseq:NP_567823.1|refseq:NP_567822.1|ensembl:ENSG00000095787(gene)|ensembl:ENST00000354911(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071894"(histone H2B conserved C-terminal lysine ubiquitination)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR038867|reactome:R-HSA-8866654|go:"GO:0016607"(nuclear speck) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:TuCxRb98Y5EGRbK1RRNMi/VnXV89606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BRD0 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2561235|ensembl:ENSP00000260210|uniprotkb:Q96LS7|uniprotkb:A8K0S0 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:bud13_human(display_long)|uniprotkb:BUD13(gene name)|psi-mi:BUD13(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENST00000260210(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0070274"(RES complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR018609|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:7ABI|rcsb pdb:7DVQ|ensembl:ENSG00000137656(gene)|refseq:NP_001153208.1|refseq:NP_116114.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:YbEsOfds3m0c4+opaoNrR+Z3rNA9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F5H3K2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886935|ensembl:ENSP00000438856 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f5h3k2_human(display_long)|uniprotkb:C12orf43(gene name)|psi-mi:C12orf43(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000157895(gene)|ensembl:ENST00000535367(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR026694 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:7M6JDnRlnbJNRBOqp+RhtDpTDl89606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:A0A1W2PP04 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886924|ensembl:ENSP00000491200 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:a0a1w2pp04_human(display_long)|uniprotkb:RBMX2(gene name)|psi-mi:RBMX2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000134597(gene)|ensembl:ENST00000639890(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:jioW83ZWoc1Uk3SdIDJjW4sl2mY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5RL73 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-473821|uniprotkb:Q9H0V7|uniprotkb:B7ZL51|uniprotkb:Q5H9T2|uniprotkb:Q8IYW7|uniprotkb:Q96NS0|intact:EBI-711530|uniprotkb:B7Z2K5|ensembl:ENSP00000265732 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rbm48_human(display_long)|uniprotkb:RBM48(gene name)|psi-mi:RBM48(display_short)|uniprotkb:C7orf64(gene name synonym)|uniprotkb:HSPC304(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:XP_005250693.1|refseq:NP_115496.2|ensembl:ENSG00000127993(gene)|ensembl:ENST00000265732(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR034264|interpro:IPR035979|interpro:IPR039599|rcsb pdb:7DVQ - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:BnBn7WG9pDLy56v88coNY6I9waI9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q2TAY7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-298027|uniprotkb:Q9BU59|uniprotkb:Q9HA96|uniprotkb:Q9NVD1|ensembl:ENSP00000380336|uniprotkb:B4E3L0 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:smu1_human(display_long)|uniprotkb:Smu-1 suppressor of mec-8 and unc-52 protein homolog(gene name synonym)|uniprotkb:SMU1(gene name)|psi-mi:SMU1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENST00000397149(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q2TAY7|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6Q8F|rcsb pdb:6Q8I|rcsb pdb:6Q8J|ensembl:ENSG00000122692(gene)|refseq:NP_060695.2 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:zbTRfKynNIUSFY8IEqyYWh3JSho9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:X6R5A3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886910|ensembl:ENSP00000345345 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:x6r5a3_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:hCG_37519(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000111802(gene)|ensembl:ENST00000341060(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:dEWNtZ5lIJnO7Y4gkBkIH4SAm8Q9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:J3QSY4 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886898|ensembl:ENSP00000366276 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:j3qsy4_human(display_long)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000145912(gene)|ensembl:ENST00000314397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR029064|refseq:NP_001030005.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:kRVeWbd8gmgNYxRazacl4UprCC89606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F5H5U6 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886889|ensembl:ENSP00000443106 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f5h5u6_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000112531(gene)|ensembl:ENST00000537124(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR036612 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:1bk/UD3e+yU+vUIo4rwxVxBgVds9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:I3L3Q7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886876|ensembl:ENSP00000460638 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:i3l3q7_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000108561(gene)|ensembl:ENST00000570805(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:5BHbLJ5giOcEIXcA2b2SLkkbPZk9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q86TS9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-10977303|ensembl:ENSP00000347277|uniprotkb:A8MYI6|uniprotkb:Q6NVH8|uniprotkb:G3XCN9|uniprotkb:A6NMQ8|uniprotkb:A8MXK5 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rm52_human(display_long)|uniprotkb:MRPL52(gene name)|psi-mi:MRPL52(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL52(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_848026.1|refseq:NP_851313.1|refseq:NP_851821.1|refseq:NP_851822.1|refseq:NP_851823.1|refseq:NP_851824.1|refseq:XP_005267385.1|ensembl:ENSG00000172590(gene)|ensembl:ENST00000355151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR034596|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:43Zs1d7+FuTPn1GioGHjL/kbZUE9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5T670 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-10985652|ensembl:ENSP00000367966 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:q5t670_human(display_long)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:hCG_40780(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000065328(gene)|ensembl:ENST00000378694(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR015411(Mcm10 replication factor)|interpro:IPR040184 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:rT9J0IlmA/QDlIK0yIGem/t6ifc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BW71 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q15059 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1383460|uniprotkb:Q5T1R7|uniprotkb:Q8N5M3|uniprotkb:Q92645|uniprotkb:Q4G5Y3|uniprotkb:B1APD9|ensembl:ENSP00000305918 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:brd3_human(display_long)|uniprotkb:BRD3(gene name)|psi-mi:BRD3(display_short)|uniprotkb:KIAA0043(gene name synonym)|uniprotkb:RING3L(gene name synonym)|uniprotkb:RING3-like protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:XP_006717354.1|refseq:NP_031397.1|refseq:XP_011517354.1|dip:DIP-39755N|ensembl:ENSG00000169925(gene)|ensembl:ENST00000303407(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|rcsb pdb:2E7N|rcsb pdb:2NXB|rcsb pdb:2OO1|rcsb pdb:2YW5|rcsb pdb:3S91|rcsb pdb:3S92|rcsb pdb:5A7C|rcsb pdb:5HFR|rcsb pdb:5HJC|rcsb pdb:6BGG|rcsb pdb:6BGH|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6U4A|rcsb pdb:6ULP|rcsb pdb:6I7A|rcsb pdb:6QJU|rcsb pdb:7JQ8|rcsb pdb:7JYN|rcsb pdb:7JYZ|rcsb pdb:7JMY - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:RIwhmbGQ4NziOcjy4M80p+TY1OQ9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9H2Z4 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-9995757|uniprotkb:Q5VZV8|ensembl:ENSP00000345147 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:nkx24_human(display_long)|uniprotkb:NKX2-4(gene name)|psi-mi:NKX2-4(display_short)|uniprotkb:NKX2D(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog D(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_149416.1|ensembl:ENSG00000125816(gene)|ensembl:ENST00000351817(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:DYK4ryzJaN1B6m3q09xe45yj9k89606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:H3BTR4 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886857|ensembl:ENSP00000457294 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:h3btr4_human(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000102901(gene)|ensembl:ENST00000564817(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:5FAs3cYK22MAIS+R8PXAOY3FCAE9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BQ48 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11158976|ensembl:ENSP00000252602|ensembl:ENSP00000469581|ensembl:ENSP00000471820 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rm34_human(display_long)|uniprotkb:MRPL34(gene name)|psi-mi:MRPL34(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL34m(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_076426.1|refseq:XP_011526491.1|ensembl:ENSG00000130312(gene)|ensembl:ENST00000252602(transcript)|ensembl:ENST00000594999(transcript)|ensembl:ENST00000600434(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000271(Ribosomal protein L34)|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF2|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:n5D2hwAW3JAag8Io9FoH+HYZq4g9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P31260 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2293516|uniprotkb:O43370|uniprotkb:O43605|uniprotkb:Q15949|uniprotkb:Q504T1|ensembl:ENSP00000283921 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:hxa10_human(display_long)|uniprotkb:HOXA10(gene name)|psi-mi:HOXA10(display_short)|uniprotkb:HOX1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1H(gene name synonym)|uniprotkb:Homeobox protein Hox-1.8(gene name synonym)|uniprotkb:PL(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_061824.3|ensembl:ENSG00000253293(gene)|ensembl:ENST00000283921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060065"(uterus development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:MLQBPBS4U2GIsWQyBQ/oZlwQLkY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P51948 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-716139|uniprotkb:Q15817|uniprotkb:G3V1U8|uniprotkb:Q6ICQ7|ensembl:ENSP00000261245 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:mat1_human(display_long)|uniprotkb:RING finger protein MAT1(gene name synonym)|uniprotkb:Menage a trois(gene name synonym)|uniprotkb:CDK7/cyclin-H assembly factor(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Cyclin-G1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 66(gene name synonym)|uniprotkb:MNAT1(gene name)|psi-mi:MNAT1(display_short)|uniprotkb:CAP35(gene name synonym)|uniprotkb:MAT1(gene name synonym)|uniprotkb:RNF66(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001171434.1|refseq:NP_002422.1|interpro:IPR017907|rcsb pdb:1G25|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6TUN|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000261245(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0021591"(ventricular system development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070985"(transcription factor TFIIK complex)|ensembl:ENSG00000020426(gene)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-HSA-8939236|refseq:XP_005267744.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:5Y/RExMrWjtftdbXuadagc0b+Kc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E9PJ24 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11137401|ensembl:ENSP00000431870 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e9pj24_human(display_long)|uniprotkb:PHRF1(gene name)|psi-mi:PHRF1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001273512.1|ensembl:ENSG00000070047(gene)|ensembl:ENST00000533464(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019786|interpro:IPR019787 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:3vg103PAL67PTeTWMYHK/vp/6Ws9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E7EUP3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886839|ensembl:ENSP00000409477 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e7eup3_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000136504(gene)|ensembl:ENST00000435742(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:hJwkpijLRHYPerxZ4J+MRvvRC3g9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:O15446 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-359424|ensembl:ENSP00000310966|uniprotkb:Q32N11|uniprotkb:Q7Z5U2|uniprotkb:Q9UPF6 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rpa34_human(display_long)|uniprotkb:RNA polymerase I-associated factor PAF49(gene name synonym)|uniprotkb:POLR1G(gene name)|psi-mi:POLR1G(display_short)|uniprotkb:A34.5(gene name synonym)|uniprotkb:ASE1(gene name synonym)|uniprotkb:Antisense to ERCC-1 protein(gene name synonym)|uniprotkb:CAST(gene name synonym)|uniprotkb:CD3-epsilon-associated protein(gene name synonym)|uniprotkb:CD3EAP(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit G(gene name synonym)|uniprotkb:PAF49(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0001650"(fibrillar center)|ensembl:ENSG00000117877(gene)|ensembl:ENST00000309424(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009303"(rRNA transcription)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|mint:O15446|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|refseq:NP_036231.1|refseq:NP_001284519.1|dip:DIP-27616N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:SRxVaX6wEST5kHqhdnE0j24EeSo9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8WVK2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2512550|ensembl:ENSP00000244227|ensembl:ENSP00000395144|uniprotkb:Q15410|intact:EBI-2557655 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:snr27_human(display_long)|uniprotkb:SNRNP27(gene name)|psi-mi:SNRNP27(display_short)|uniprotkb:U4/U6.U5 tri-snRNP-associated protein 3(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP-associated 27 kDa protein(gene name synonym)|uniprotkb:Nucleic acid-binding protein RY-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000124380(gene)|ensembl:ENST00000244227(transcript)|ensembl:ENST00000450162(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR013957(Protein of unknown function DUF1777)|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_006848.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:wSOfld20fuDA9ZN9vDXLilFmmSs9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P56182 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q15007 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-751647|uniprotkb:Q96T28|uniprotkb:Q9BYJ7|uniprotkb:Q9H4E2|uniprotkb:Q5TCL8|uniprotkb:Q5TCL9|ensembl:ENSP00000351141|ensembl:ENSP00000479438 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:fl2d_human(display_long)|uniprotkb:Wilms tumor 1-associating protein(gene name synonym)|uniprotkb:WT1-associated protein(gene name synonym)|uniprotkb:"Female-lethal(2)D homolog"(gene name synonym)|uniprotkb:WTAP(gene name)|psi-mi:WTAP(display_short)|uniprotkb:KIAA0105(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_004897.2|refseq:NP_690596.1|refseq:NP_690597.1|refseq:NP_001257460.1|refseq:NP_001257461.1|refseq:NP_001257462.1|ensembl:ENST00000337387|ensembl:ENSP00000336911|ensembl:ENSP00000351141|ensembl:ENSP00000479438|ensembl:ENST00000650096|ensembl:ENSP00000497840|dip:DIP-57185N|ensembl:ENSG00000146457(gene)|ensembl:ENST00000358372(transcript)|ensembl:ENST00000621533(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0080009"(mRNA methylation)|interpro:IPR029732|interpro:IPR033757|mint:Q15007|reactome:R-HSA-72203 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:oXRJPz4LKLT0fDVFQArL4ELUc089606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9Y673 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11725055|uniprotkb:B4DR37|uniprotkb:Q5TBA6|ensembl:ENSP00000239891 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:alg5_human(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:Asparagine-linked glycosylation protein 5 homolog(gene name synonym)|uniprotkb:HSPC149(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001135836.1|refseq:NP_037470.1|ensembl:ENSG00000120697(gene)|ensembl:ENST00000239891(transcript)|go:"GO:0004576"(oligosaccharyl transferase activity)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-HSA-480985 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:BrOq249TNUXkpnFulYQvYILVHUA9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9ULM0 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2803624|uniprotkb:Q6ZWC7|uniprotkb:A6H8X6|uniprotkb:Q6PJL4|ensembl:ENSP00000330278 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:pkhh1_human(display_long)|uniprotkb:KIAA1200(gene name synonym)|uniprotkb:PLEKHH1(gene name)|psi-mi:PLEKHH1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000054690(gene)|ensembl:ENST00000329153(transcript)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR038185|interpro:IPR040105|refseq:NP_065766.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:ONtvImmlJVWndi7ktHfkGZ1odWw9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q6NWY9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11285481|uniprotkb:O75401|uniprotkb:Q6PI09|uniprotkb:Q6ZWB3|uniprotkb:Q8NCZ1|uniprotkb:Q9H5G4|uniprotkb:Q9NT95|intact:EBI-28973519|ensembl:ENSP00000369634 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:pr40b_human(display_long)|uniprotkb:PRPF40B(gene name)|psi-mi:PRPF40B(display_short)|uniprotkb:HYPC(gene name synonym)|uniprotkb:Huntingtin yeast partner C(gene name synonym)|uniprotkb:Huntingtin-interacting protein C(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENST00000261897|ensembl:ENSP00000261897|ensembl:ENSP00000369634|refseq:NP_001026868.2|refseq:NP_036404.1|refseq:XP_011536443.1|ensembl:ENSG00000110844(gene)|ensembl:ENST00000380281(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002713(FF)|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726|go:"GO:0003723"(RNA binding) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:zKyhm7thvLVCncYn6kXrHeNbfJE9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q13257 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P17482 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-745290|uniprotkb:Q9H1I1|uniprotkb:B2RDB7|ensembl:ENSP00000309439 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:hxb9_human(display_long)|uniprotkb:Homeobox protein Hox-2E(gene name synonym)|uniprotkb:Homeobox protein Hox-2.5(gene name synonym)|uniprotkb:HOXB9(gene name)|psi-mi:HOXB9(display_short)|uniprotkb:HOX2E(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_076922.1|ensembl:ENSG00000170689(gene)|ensembl:ENST00000311177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030879"(mammary gland development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006711(Hox9 activation region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017112(Homeobox, Hox9)|interpro:IPR017970|interpro:IPR020479|mint:P17482 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:1pOMN5hO0W2eq4PII7uRN7EZ7DY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8N1B3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-3925043|uniprotkb:Q9BUU1|uniprotkb:Q330J9|uniprotkb:Q96IU5|uniprotkb:Q2I380|ensembl:ENSP00000461135 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:ccnq_human(display_long)|uniprotkb:CCNQ(gene name)|psi-mi:CCNQ(display_short)|uniprotkb:CDK10-activating cyclin(gene name synonym)|uniprotkb:Cyclin-M(gene name synonym)|uniprotkb:Cyclin-related protein FAM58A(gene name synonym)|uniprotkb:FAM58A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001124469.1|refseq:NP_689487.2|ensembl:ENSG00000262919(gene)|ensembl:ENST00000576892(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028759|interpro:IPR036915|interpro:IPR043198 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:Sf+D49tbedmVh6y8aOZb3Ou9fbI9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:S5FZ81 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886829|ensembl:ENSP00000479515 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:s5fz81_human(display_long)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000130024(gene)|ensembl:ENST00000612128(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071564"(npBAF complex)|interpro:IPR038045 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:8m9TN1D6SDaQdkeH9Of/LEUDbsY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:A0A087WUY7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886812|ensembl:ENSP00000479025 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:a0a087wuy7_human(display_long)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000078043(gene)|ensembl:ENST00000592212(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019789"(SUMO transferase activity)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027228|interpro:IPR036361|interpro:IPR038654 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:+5yB4KkabNyyythPAd6XrO5Hx3Q9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:A6NCC9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886804|ensembl:ENSP00000370380 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:a6ncc9_human(display_long)|uniprotkb:TSSC4(gene name)|psi-mi:TSSC4(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000184281(gene)|ensembl:ENST00000380992(transcript)|interpro:IPR029338 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:ZCW5BisXTZu5cfs4KRzQfx8ll289606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9NW64 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060517.1|go:"GO:0035690"|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|ensembl:ENST00000199814(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000086589(gene)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q86V97 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2514778|ensembl:ENSP00000368799|uniprotkb:Q96MP6|uniprotkb:Q8NDM5|uniprotkb:Q5T6Y8|uniprotkb:Q8N8L0 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:kbtb6_human(display_long)|uniprotkb:KBTBD6(gene name)|psi-mi:KBTBD6(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000165572(gene)|ensembl:ENST00000379485(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:4XC2|refseq:NP_690867.3 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:iMugkQiayHqkx3aiExLs32a5Bv49606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q96ST2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2515615|ensembl:ENSP00000295321|uniprotkb:Q2TB65|uniprotkb:Q9NV97|uniprotkb:Q96MI7|uniprotkb:Q9NWH8|uniprotkb:Q6P157|uniprotkb:Q8N3E8 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:iws1_human(display_long)|uniprotkb:IWS1(gene name)|psi-mi:IWS1(display_short)|uniprotkb:IWS1L(gene name synonym)|uniprotkb:IWS1-like protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000163166(gene)|ensembl:ENST00000295321(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0090239"(regulation of histone H4 acetylation)|go:"GO:2001253"(regulation of histone H3-K36 trimethylation)|interpro:IPR017923|interpro:IPR035441|mint:Q96ST2|rcsb pdb:6EMR|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|refseq:NP_060439.2 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:G7KjbkwlfWdg2VufnJfRBiS/yUs9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9UK58 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2836773|uniprotkb:B3KMY3|uniprotkb:Q96QT0|uniprotkb:Q9NZF3|uniprotkb:Q8NI48|uniprotkb:Q6NVY9|uniprotkb:Q6UWS7|intact:EBI-11158173|uniprotkb:C9JPL0|ensembl:ENSP00000295926 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:ccnl1_human(display_long)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_064703.1|refseq:NP_001295114.1|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015431(Cyclin L, metazoan)|interpro:IPR036915|interpro:IPR043198|mint:Q9UK58|refseq:XP_016862381.1|refseq:XP_016862382.1|refseq:XP_016862383.1|refseq:XP_016862384.1|refseq:XP_016862385.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q15131 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1646959|uniprotkb:A8MXU6|uniprotkb:Q0VGZ7|uniprotkb:Q15130|uniprotkb:Q6PJC0|uniprotkb:D3DX82|uniprotkb:D3DX83|uniprotkb:A8K370|uniprotkb:A8K8I6|uniprotkb:B3KQJ3|uniprotkb:B7Z420|ensembl:ENSP00000338673 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:cdk10_human(display_long)|uniprotkb:CDK10(gene name)|psi-mi:CDK10(display_short)|uniprotkb:Serine/threonine-protein kinase PISSLRE(gene name synonym)|uniprotkb:Cell division protein kinase 10(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001092003.2|refseq:NP_001153839.1|refseq:NP_443713.2|refseq:NP_443714.3|refseq:XP_016879297.1|refseq:XP_016879298.1|refseq:XP_016879299.1|ensembl:ENSG00000185324(gene)|ensembl:ENST00000353379(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030030"(cell projection organization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044093|mint:Q15131 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:JeOkdG542xQIEDF5hL+83aPl1IQ9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E9PLD3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11069715|ensembl:ENSP00000435188 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e9pld3_human(display_long) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 interpro:IPR037691|ensembl:ENSG00000255432(gene)|ensembl:ENST00000528405(transcript) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:iUSmjd2roGizUINccsCQiCyeGbM9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P42568 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:O95926 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2557644|uniprotkb:Q5TH73|ensembl:ENSP00000236273 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:syf2_human(display_long)|uniprotkb:SYF2(gene name)|psi-mi:SYF2(display_short)|uniprotkb:CBPIN(gene name synonym)|uniprotkb:GCIPIP(gene name synonym)|uniprotkb:CCNDBP1-interactor(gene name synonym)|uniprotkb:p29(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_056299.1|refseq:NP_997053.1|ensembl:ENSG00000117614(gene)|ensembl:ENST00000236273(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0048568"(embryonic organ development)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR013260(mRNA splicing factor SYF2)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-72163 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:0kjA0uwfwSUPQECIFbtP1ih9o009606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5TBH9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886795|ensembl:ENSP00000321341 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:q5tbh9_human(display_long)|uniprotkb:C1orf131(gene name)|psi-mi:C1orf131(display_short)|uniprotkb:hCG_14915(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000143633(gene)|ensembl:ENST00000318906(transcript)|interpro:IPR027973 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:dRGsJQVzn5KUDRnFVZA/6stOu5s9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8TCC3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11038252|uniprotkb:Q9P0N0|uniprotkb:A6NIC6|uniprotkb:D3DVI0|uniprotkb:Q0D2Q7|uniprotkb:Q6ZTP4|uniprotkb:Q96Q69|uniprotkb:D3DVI3|ensembl:ENSP00000338057|ensembl:ENSP00000386752 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rm30_human(display_long)|uniprotkb:MRPL30(gene name)|psi-mi:MRPL30(display_short)|uniprotkb:39S ribosomal protein L28, mitochondrial(gene name synonym)|uniprotkb:MRPL28(gene name synonym)|uniprotkb:RPML28(gene name synonym)|uniprotkb:HSPC249(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL30m(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_660213.1|interpro:IPR036919|mint:Q8TCC3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|interpro:IPR016082(Ribosomal protein L30, C-terminal)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000185414(gene)|ensembl:ENST00000338148(transcript)|ensembl:ENST00000409841(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR005996(Ribosomal protein L30, bacterial-type) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:B9fWF4LjIKSO3Cg2+oLuH2KQjfE9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BW85 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-10300345|uniprotkb:Q9NW16|uniprotkb:O75270|uniprotkb:Q9H862|ensembl:ENSP00000262962 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:yju2_human(display_long)|uniprotkb:YJU2(gene name)|psi-mi:YJU2(display_short)|uniprotkb:CCDC94(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 94(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060544.2|ensembl:ENSG00000105248(gene)|ensembl:ENST00000262962(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0008380"(RNA splicing)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR007590(Protein of unknown function DUF572)|interpro:IPR043701|rcsb pdb:5YZG|rcsb pdb:6ZYM|rcsb pdb:7A5P - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:BSnLgJgsbNZtO1nmgWddL3QYth09606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q99680 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-3907043|uniprotkb:O14554|ensembl:ENSP00000302676|ensembl:ENSP00000492841|uniprotkb:A4D0R8 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:gpr22_human(display_long)|uniprotkb:GPR22(gene name)|psi-mi:GPR22(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:XP_011514358.1|refseq:NP_005286.2|ensembl:ENSG00000172209(gene)|ensembl:ENSG00000283812(gene)|ensembl:ENST00000304402(transcript)|ensembl:ENST00000639742(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030030"(cell projection organization)|go:"GO:0042277"(peptide binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:KjeDvxSHa3Yz4AYfvzpDqtSS1fU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q6PK04 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-714654|ensembl:ENSP00000329360|ensembl:ENSP00000458884 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:cc137_human(display_long)|uniprotkb:CCDC137(gene name)|psi-mi:CCDC137(display_short)|uniprotkb:cPERP-B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_954981.1|ensembl:ENSG00000185298(gene)|ensembl:ENST00000329214(transcript)|ensembl:ENST00000575223(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR026680|mint:Q6PK04 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:e64Y/4oJpFqmYZEO1lOUHeLwy0I9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q6I9Y2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:15M7nouxNuzlKZPawajrahz0LAY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F5H702 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886780|ensembl:ENSP00000321539|ensembl:ENSP00000381497|ensembl:ENSP00000399076 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f5h702_human(display_long)|uniprotkb:MRPL48(gene name)|psi-mi:MRPL48(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000175581(gene)|ensembl:ENST00000314282(transcript)|ensembl:ENST00000398483(transcript)|ensembl:ENST00000411840(transcript)|go:"GO:0005761"(mitochondrial ribosome)|interpro:IPR027486|interpro:IPR027487|interpro:IPR036838 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:q8O+8eYhgQcJ2GBzU3bThlNr93k9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:B2WTI3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11117022|ensembl:ENSP00000302916 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:b2wti3_human(display_long)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:hCG_30900(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000070495(gene)|ensembl:ENST00000303996(transcript)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:7kWuVxVoB97uoh2MxNmlYod15pI9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8TA86 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-630339|ensembl:ENSP00000297157 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rp9_human(display_long)|uniprotkb:Pim-1-associated protein(gene name synonym)|uniprotkb:RP9(gene name)|psi-mi:RP9(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_976033.1|ensembl:ENSG00000164610(gene)|ensembl:ENST00000297157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050890"(cognition)|interpro:IPR034585 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:aLu5MPtPUaFvJYBLKJ+ObI4c0OQ9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9HAF1 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P52756 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:J3QR07 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-11103255|ensembl:ENSP00000463982|ensembl:ENSP00000486746 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:j3qr07_human(display_long)|uniprotkb:YTHDC1(gene name)|psi-mi:YTHDC1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000083896(gene)|ensembl:ENSG00000275272(gene)|ensembl:ENST00000579690(transcript)|ensembl:ENST00000627168(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|interpro:IPR007275(YT521-B-like protein)|refseq:NP_001317627.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:aWCU7I9QIjgU8fdiqIXfSdF4d+g9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E9PGA7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886770|ensembl:ENSP00000418682 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e9pga7_human(display_long)|uniprotkb:FRMD4B(gene name)|psi-mi:FRMD4B(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000114541(gene)|ensembl:ENST00000478263(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR021774|refseq:XP_005264780.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:V5j/TnHuIxBP7ox8BaIUOBLlH3U9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9NXE8 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-746052|uniprotkb:A0JLM3|uniprotkb:Q68DK5|ensembl:ENSP00000477799|ensembl:ENSP00000478070 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:cwc25_human(display_long)|uniprotkb:CWC25(gene name)|psi-mi:CWC25(display_short)|uniprotkb:CCDC49(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 49(gene name synonym)|uniprotkb:Spliceosome-associated protein homolog CWC25(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060218.1|ensembl:ENSG00000273559(gene)|ensembl:ENSG00000276761(gene)|ensembl:ENST00000614790(transcript)|ensembl:ENST00000614868(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR019339|interpro:IPR022209|mint:Q9NXE8|rcsb pdb:5YZG|rcsb pdb:6ZYM|reactome:R-HSA-72163 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:tHUYBNAjYV/4gMcTCaos3Yo+DwY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:C9J4Z3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26879112|ensembl:ENSP00000410240 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:c9j4z3_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:hCG_16380(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000197756(gene)|ensembl:ENST00000456586(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:0nxdml251Ald69ggi8cUJOsn90U9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5QPM0 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-21262411|ensembl:ENSP00000327522 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:q5qpm0_human(display_long)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000125970(gene)|ensembl:ENST00000333552(transcript) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:xD9IkARBjlMfIyiiB2xbgBgrTFo9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P61244 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9GZS1 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-359458|uniprotkb:Q5VZT3|uniprotkb:Q8NBA9|uniprotkb:Q96L20|ensembl:ENSP00000367029|intact:EBI-21026140 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rpa49_human(display_long)|uniprotkb:POLR1E(gene name)|psi-mi:POLR1E(display_short)|uniprotkb:PAF53(gene name synonym)|uniprotkb:PRAF1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit E(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 1(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 53(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001269695.1|refseq:NP_071935.1|ensembl:ENSG00000137054(gene)|ensembl:ENST00000377798(transcript)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|mint:Q9GZS1|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|reactome:R-HSA-427413|refseq:XP_005251604.1|dip:DIP-27546N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:3cidLGlybOTCIJGQ6xweDrvBBYM9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q86X95 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-627102|ensembl:ENSP00000339723|uniprotkb:A6NFI6|uniprotkb:A8K8M4|uniprotkb:O95367|uniprotkb:Q12804|uniprotkb:Q4G1B9|uniprotkb:Q6PJI4|uniprotkb:Q8IWI2 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:cir1_human(display_long)|uniprotkb:CIR(gene name synonym)|uniprotkb:CBF1-interacting corepressor(gene name synonym)|uniprotkb:Recepin(gene name synonym)|uniprotkb:CIR1(gene name)|psi-mi:CIR1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000138433(gene)|ensembl:ENST00000342016(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR019339|interpro:IPR040014|mint:Q86X95|rcsb pdb:6ZYM|refseq:NP_004873.3 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:DMnBG746eQpvLsf9D+lgeUKnni09606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P27707 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-715861|uniprotkb:Q5TZY7|uniprotkb:Q6FI11|uniprotkb:B2R8V6|ensembl:ENSP00000286648 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:dck_human(display_long)|uniprotkb:Deoxyadenosine kinase(gene name synonym)|uniprotkb:Deoxyguanosine kinase(gene name synonym)|uniprotkb:DCK(gene name)|psi-mi:DCK(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_000779.1|ensembl:ENSG00000156136(gene)|ensembl:ENST00000286648(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004137"(deoxycytidine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|mint:P27707|rcsb pdb:1P5Z|rcsb pdb:1P60|rcsb pdb:1P61|rcsb pdb:1P62|rcsb pdb:2A2Z|rcsb pdb:2A30|rcsb pdb:2A7Q|rcsb pdb:2NO0|rcsb pdb:2NO1|rcsb pdb:2NO6|rcsb pdb:2NO7|rcsb pdb:2NO9|rcsb pdb:2NOA|rcsb pdb:2QRN|rcsb pdb:2QRO|rcsb pdb:2ZI3|rcsb pdb:2ZI4|rcsb pdb:2ZI5|rcsb pdb:2ZI6|rcsb pdb:2ZI7|rcsb pdb:2ZI9|rcsb pdb:2ZIA|rcsb pdb:3HP1|rcsb pdb:3IPX|rcsb pdb:3IPY|rcsb pdb:3KFX|rcsb pdb:3MJR|rcsb pdb:3QEJ|rcsb pdb:3QEN|rcsb pdb:3QEO|rcsb pdb:4JLJ|rcsb pdb:4JLK|rcsb pdb:4JLM|rcsb pdb:4JLN|rcsb pdb:4KCG|rcsb pdb:4L5B|rcsb pdb:4Q18|rcsb pdb:4Q19|rcsb pdb:4Q1A|rcsb pdb:4Q1B|rcsb pdb:4Q1C|rcsb pdb:4Q1D|rcsb pdb:4Q1E|rcsb pdb:4Q1F|rcsb pdb:5MQJ|rcsb pdb:5MQL|rcsb pdb:5MQT|reactome:R-HSA-73614|reactome:R-HSA-74217 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:ikpxlOM4Z3EKULMzh9TTIqP/moc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q6ZUT1 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-3920396|ensembl:ENSP00000339076|ensembl:ENSP00000402208|uniprotkb:Q7Z357|uniprotkb:Q8N2T3|uniprotkb:Q6IN53|uniprotkb:Q5RL41 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:nkap1_human(display_long)|uniprotkb:NKAPD1(gene name)|psi-mi:NKAPD1(display_short)|uniprotkb:C11orf57(gene name synonym)|uniprotkb:NKAP domain containing protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000150776(gene)|ensembl:ENST00000280352(transcript)|ensembl:ENST00000420986(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR043407|refseq:NP_001287946.1|refseq:NP_001287948.1|refseq:NP_001287950.1|refseq:NP_001076439.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:7Lz1Il3OjnAW5tcASdyVUZf+4y89606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9BQC6 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1055359|uniprotkb:A2A332|ensembl:ENSP00000310726 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rt63_human(display_long)|uniprotkb:MRPL57(gene name)|psi-mi:MRPL57(display_short)|uniprotkb:MRP63(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein 63(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein L57(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL63(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_076931.1|ensembl:ENSG00000173141(gene)|ensembl:ENST00000309594(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR016576(Mitochondrial ribosomal protein 63)|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016876229.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:RErvYq/pbOr8ZZWW9+dJr4eVknQ9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9HCD5 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9P031 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1047110|uniprotkb:Q9H2V5|uniprotkb:Q9NW62|ensembl:ENSP00000256151 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:tap26_human(display_long)|uniprotkb:TTF-1-associated protein BR2(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 59(gene name synonym)|uniprotkb:CCDC59(gene name)|psi-mi:CCDC59(display_short)|uniprotkb:BR22(gene name synonym)|uniprotkb:TAP26(gene name synonym)|uniprotkb:HSPC128(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_054886.2|ensembl:ENSG00000133773(gene)|ensembl:ENST00000256151(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR013730(rRNA processing)|reactome:R-HSA-5683826 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:p0UHejV9vxOkT8NrUysz7hmdOW49606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9NZE8 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2809397|uniprotkb:Q8WWA2|uniprotkb:Q658U7|uniprotkb:B2RB93|uniprotkb:A6NKV6|ensembl:ENSP00000338389 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rm35_human(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL35m(gene name synonym)|uniprotkb:BM-007(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_057706.2|refseq:NP_663619.1|ensembl:ENSG00000132313(gene)|ensembl:ENST00000337109(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR019338|interpro:IPR021137|interpro:IPR037229|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:qnBAYkLrqSc62X16EcCAI+Yrtaw9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P51991 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P35659 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:M0R268 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886758|ensembl:ENSP00000472355 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:m0r268_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000077312(gene)|ensembl:ENST00000601393(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:BB+qkDdG1DDAsSqwr23CzW4VHxg9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q6P6C2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-5280436|uniprotkb:D3DXC6|uniprotkb:Q9NXD6|uniprotkb:B4DVJ4|ensembl:ENSP00000382091 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:alkb5_human(display_long)|uniprotkb:ALKBH5(gene name)|psi-mi:ALKBH5(display_short)|uniprotkb:ABH5(gene name synonym)|uniprotkb:OFOXD1(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 5(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060228.3|ensembl:ENSP00000382091|ensembl:ENSG00000091542(gene)|ensembl:ENST00000399138(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035553"(oxidative single-stranded RNA demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:1990931"(mRNA N6-methyladenosine dioxygenase activity)|interpro:IPR027450|interpro:IPR032860|interpro:IPR037151|rcsb pdb:4NJ4|rcsb pdb:4NRM|rcsb pdb:4NRO|rcsb pdb:4NRP|rcsb pdb:4NRQ|rcsb pdb:4O61|rcsb pdb:4O7X|rcsb pdb:4OCT|reactome:R-HSA-73943|go:"GO:0043488"(regulation of mRNA stability) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:PD25zPFQPS2gC0z7A8wrWMON3Bk9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q96EY4 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1045338|uniprotkb:Q0P6E4|uniprotkb:Q0P6J1|uniprotkb:Q9NUR7|ensembl:ENSP00000351380 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:tma16_human(display_long)|uniprotkb:TMA16(gene name)|psi-mi:TMA16(display_short)|uniprotkb:C4orf43(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060822.2|ensembl:ENSG00000198498(gene)|ensembl:ENST00000358572(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR021346|interpro:IPR038356|mint:Q96EY4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:SpEUtN6fodLyKZOgY6Y7AXfVBRY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:G3XAI9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886748|ensembl:ENSP00000389559 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:g3xai9_human(display_long)|uniprotkb:FAM133B(gene name)|psi-mi:FAM133B(display_short)|uniprotkb:MGC40405(gene name synonym)|uniprotkb:hCG_19545(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000234545(gene)|ensembl:ENST00000415397(transcript)|interpro:IPR026766 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:4Lm4gpQ9TZJTSp1nwZ3Uu2nIBhM9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:O94992 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8NEF9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:MQv9j4+l9h+7z05X/bRJAompesc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:B3KVL5 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886735|ensembl:ENSP00000347533 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:b3kvl5_human(display_long)|uniprotkb:ZCCHC10(gene name)|psi-mi:ZCCHC10(display_short)|uniprotkb:hCG_1639963(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000155329(gene)|ensembl:ENST00000355372(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036875|interpro:IPR039715|refseq:NP_001287746.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:V0jSjhLOA9lck0N7wcl8mq6FDhM9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:B7WP74 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886723|ensembl:ENSP00000384159 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:b7wp74_human(display_long)|uniprotkb:CWC22(gene name)|psi-mi:CWC22(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000163510(gene)|ensembl:ENST00000404136(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:r41lHHgfvD54srREEcviu05gJFg9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F8W0Q9 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886712|ensembl:ENSP00000447168 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f8w0q9_human(display_long)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000134283(gene)|ensembl:ENST00000549190(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR028851 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:Grm2UoL0ad+TtdyhtWsTIAWx7lA9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5VTL8 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1045334|uniprotkb:Q05DD6|uniprotkb:Q32Q58|uniprotkb:Q5VTL9|uniprotkb:Q6PK39|uniprotkb:Q7Z6E2|uniprotkb:Q86WF3|uniprotkb:Q8IWG9|uniprotkb:Q9NW40|ensembl:ENSP00000359042 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:pr38b_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-27(gene name synonym)|uniprotkb:PRPF38B(gene name)|psi-mi:PRPF38B(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_060531.2|ensembl:ENSG00000134186(gene)|ensembl:ENST00000370025(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005037(PRP38) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:AWwws/iWEHoeyV7o3bgLKBQKgQ49606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9H0U6 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-2560240|uniprotkb:Q5TAP9|uniprotkb:Q9NZW8|ensembl:ENSP00000356001 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rm18_human(display_long)|uniprotkb:MRPL18(gene name)|psi-mi:MRPL18(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL18m(gene name synonym)|uniprotkb:HSPC071(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_054880.2|ensembl:ENSG00000112110(gene)|ensembl:ENST00000367034(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0035928"(rRNA import into mitochondrion)|interpro:IPR005484(Ribosomal protein L18/L5)|interpro:IPR036967|mint:Q9H0U6|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001305746.1|dip:DIP-56844N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:MtxdrTVdqAfWZqnuxD+PGs218/A9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q9NPE3 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1642169|ensembl:ENSP00000332198 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:nop10_human(display_long)|uniprotkb:NOLA3(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_061118.1|dip:DIP-40092N|ensembl:ENSG00000182117(gene)|ensembl:ENST00000328848(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016604"(nuclear body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|mint:Q9NPE3|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:gBAwyGcfJTBMf8Q+fQZ/fDcPEBc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P52298 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P09234 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-766589|uniprotkb:Q5TAL3|ensembl:ENSP00000244520 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:ru1c_human(display_long)|uniprotkb:SNRPC(gene name)|psi-mi:SNRPC(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_003084.1|dip:DIP-34235N|ensembl:ENSG00000124562(gene)|ensembl:ENST00000244520(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030627"(pre-mRNA 5'-splice site binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013085(Zinc finger, U1-C type)|interpro:IPR017340(U1 small nuclear ribonucleoprotein C)|interpro:IPR036236|mint:P09234|rcsb pdb:2VRD|rcsb pdb:3CW1|rcsb pdb:4PJO|rcsb pdb:6ELD|rcsb pdb:6QX9|reactome:R-HSA-72163 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:igW6pKnj1LJmvvs7PIWx03ip6Is9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F5H0Q6 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886700|ensembl:ENSP00000438702 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f5h0q6_human(display_long)|uniprotkb:CLASRP(gene name)|psi-mi:CLASRP(display_short)|uniprotkb:SFRS16(gene name synonym)|uniprotkb:hCG_22138(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000104859(gene)|ensembl:ENST00000544944(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR019147|interpro:IPR040397 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:p1rxoB5iqJXSwuo4JzSmoT1nw489606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8IZ73 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-1965305|uniprotkb:Q7L989|uniprotkb:Q96IA7|uniprotkb:Q96N50|uniprotkb:Q92939|uniprotkb:B4DDD1|ensembl:ENSP00000323288 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rusd2_human(display_long)|uniprotkb:C15orf19(gene name synonym)|uniprotkb:RPUSD2(gene name)|psi-mi:RPUSD2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001273336.1|refseq:NP_689473.1|ensembl:ENSG00000166133(gene)|ensembl:ENST00000315616(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR006224(Pseudouridine synthase, conserved site)|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR020103 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:kMNtEnFtGXvR+JgrajRHGFVi/d09606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E9PES6 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886685|ensembl:ENSP00000417027 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e9pes6_human(display_long)|uniprotkb:HMGB3(gene name)|psi-mi:HMGB3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000029993(gene)|ensembl:ENST00000430118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0045087"(innate immune response)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031077|interpro:IPR036910 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:ZTzyvxqgUs6dlqPvzy5agEfIGL49606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:K7EIY1 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886677|ensembl:ENSP00000464939 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:k7eiy1_human(display_long)|uniprotkb:FAM32A(gene name)|psi-mi:FAM32A(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000105058(gene)|ensembl:ENST00000588367(transcript)|interpro:IPR013865(Protein of unknown function DUF1754, eukaryotic) - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:V1t/X3HYfvKQ6WCv9QOw8VwXqvk9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:P35637 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:D3DTZ5 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886662|ensembl:ENSP00000462100 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:d3dtz5_human(display_long)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:hCG_2002775(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000213246(gene)|ensembl:ENST00000577396(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:ep8Id54VanJ4s2+RDhwSbS+Ja5I9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:E9PK91 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26659035|ensembl:ENSP00000435441 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:e9pk91_human(display_long)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000029363(gene)|ensembl:ENST00000527536(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR026668|interpro:IPR029199|refseq:XP_005267294.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:JLJvqVJNrQw/XyCJ8HfFXC++l9g9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q8N5F7 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-721539|uniprotkb:Q96BQ2|uniprotkb:Q9H638|intact:EBI-745962|intact:EBI-1055594|uniprotkb:Q6IPW6|ensembl:ENSP00000360464 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:nkap_human(display_long)|uniprotkb:NKAP(gene name)|psi-mi:NKAP(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 refseq:NP_078804.2|ensembl:ENSG00000101882(gene)|ensembl:ENST00000371410(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q8N5F7|rcsb pdb:6QDV - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:AiSgP+Qr12IZX1LBTsna82wmkks9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:F5GYV5 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886652|ensembl:ENSP00000441406 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:f5gyv5_human(display_long)|uniprotkb:ARL6IP4(gene name)|psi-mi:ARL6IP4(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000182196(gene)|ensembl:ENST00000413381(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016607"(nuclear speck)|interpro:IPR019532 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:K0OQXPxMErAGbrKM1IKwo9vpRYw9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q7L4I2 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-953753|ensembl:ENSP00000330188|uniprotkb:Q6N040|uniprotkb:Q9H864|uniprotkb:Q6NW16 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:rsrc2_human(display_long)|uniprotkb:RSRC2(gene name)|psi-mi:RSRC2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000111011(gene)|ensembl:ENST00000331738(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR028124|refseq:NP_075388.2|refseq:XP_016875322.1 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:Q1+9cflZJRsWlCxJFyt2mi15KxY9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NWB6 uniprotkb:Q5T7C4 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 intact:EBI-26886636|ensembl:ENSP00000369904|ensembl:ENSP00000382412 psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:q5t7c4_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-26886979|imex:IM-28821-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 ensembl:ENSG00000189403(gene)|ensembl:ENST00000326004(transcript)|ensembl:ENST00000399489(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0045087"(innate immune response)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910 - - - figure legend:ST5, F3A|comment:Only the top 100 enriched proteins have been annotated, the complited list of BirA*-ARGLU1 interactors is available in ST5.|comment:Cells were treated wih dexamethasone|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rogid:GjV9V/8quMsgmCQdjWWbG/kZbgo9606 rigid:pMGWr4XZLgMwkz9IP6auD2XSwJo false fusion protein:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UHX1 uniprotkb:Q9NWB6 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26888090|imex:IM-28821-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:rFPnGMrJRJWLYQB95mfl1eIqr+Y false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P26368 uniprotkb:Q9NWB6 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26888098|imex:IM-28821-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 - - - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:nCXhKwfHMUCKB/J0HML1853dS8Y false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6NYC1 uniprotkb:Q9NWB6 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26888106|imex:IM-28821-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses - figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/19 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:ek/Vd9uNC6AMKu4KP4LKzszFpjo false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3UL36 uniprotkb:Q9R0N0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-3870529|intact:EBI-8362283|intact:MINT-4129760|uniprotkb:Q9JIA6|ensembl:ENSMUSP00000021114 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:galk1_mouse(display_long)|uniprotkb:Galk1(gene name)|psi-mi:Galk1(display_short)|uniprotkb:Galk(gene name synonym)|uniprotkb:Glk(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_058601.2|ensembl:ENSMUSG00000020766(gene)|ensembl:ENSMUST00000021114(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0033499"(galactose catabolic process via UDP-galactose)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0061623"(glycolytic process from galactose)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:Q9R0N0|reactome:R-MMU-70370 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:4kVUQtJtkIYvnEpR581pKry69aE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9DAW6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8339354|intact:MINT-4127974|ensembl:ENSMUSP00000081572 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:prp4_mouse(display_long)|uniprotkb:Prpf4(gene name)|psi-mi:Prpf4(display_short)|uniprotkb:U4/U6 snRNP 60 kDa protein(gene name synonym)|uniprotkb:WD splicing factor Prp4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_081573.1|ensembl:ENSMUSG00000066148(gene)|ensembl:ENSMUST00000084524(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097525"(spliceosomal snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036285|interpro:IPR036322|mint:Q9DAW6|reactome:R-MMU-72163 - - comment:mint|function:Involved in pre-mRNA splicing comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:24EWvP4WL+PEkEUaA6JvVM85kD010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9Z103 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8338941|uniprotkb:A2BDX0|intact:MINT-4087285|ensembl:ENSMUSP00000056809|ensembl:ENSMUSP00000085316 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:adnp_mouse(display_long)|uniprotkb:Adnp(gene name)|psi-mi:Adnp(display_short)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001297015.1|refseq:NP_033758.2|ensembl:ENSMUSG00000051149(gene)|ensembl:ENSMUST00000057793(transcript)|ensembl:ENSMUST00000088001(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9Z103 - - function:Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:PSS9JEDZ+k4ClBvuqSKHNm9a+Z410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9D0F4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8429930|intact:MINT-4126413|uniprotkb:Q8BTK6|uniprotkb:Q8R324|uniprotkb:Q8BYT5|uniprotkb:Q9CSH4|ensembl:ENSMUSP00000016553 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:nkap_mouse(display_long)|uniprotkb:Nkap(gene name)|psi-mi:Nkap(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_080213.3|ensembl:ENSMUSG00000016409(gene)|ensembl:ENSMUST00000016553(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q9D0F4 - - comment:mint|function:Regulator of TNF and IL-1 induced NF-kappa-B activation comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:2QBUDGUPz3oY0e5Og0Cx3Pnp7e810090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8VBX6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8026435|uniprotkb:Q8VBV5|uniprotkb:Q6P7U4|uniprotkb:Q8VBY0|uniprotkb:B7ZNA1|uniprotkb:Q9Z1K3|uniprotkb:O08783|uniprotkb:Q8BKJ1|uniprotkb:Q8C0H8|intact:MINT-146667|uniprotkb:Q80ZY8|ensembl:ENSMUSP00000099894 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:mpdz_mouse(display_long)|uniprotkb:Mpdz(gene name)|psi-mi:Mpdz(display_short)|uniprotkb:Mupp1(gene name synonym)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001292213.1|refseq:NP_001292215.1|refseq:NP_034950.2|dip:DIP-41165N|ensembl:ENSMUSG00000028402(gene)|ensembl:ENSMUST00000102830(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042552"(myelination)|go:"GO:0043220"(Schmidt-Lanterman incisure)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:Q8VBX6|rcsb pdb:4XH7 - - comment:mint|function:Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:PE6FMj7RyxofEiUpGMu97CF+TX810090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BFU3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8314085|ensembl:ENSMUSP00000060941|ensembl:ENSMUSP00000123754|uniprotkb:Q8CCP2|uniprotkb:Q8CC56|intact:MINT-4119265|uniprotkb:Q80VI8|uniprotkb:Q3UWM9|uniprotkb:Q8R5B9|uniprotkb:Q6P3A7|uniprotkb:Q8CE92|uniprotkb:Q8BNZ6 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rn214_mouse(display_long)|uniprotkb:Rnf214(gene name)|psi-mi:Rnf214(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001297768.1|refseq:NP_001297769.1|ensembl:ENSMUSG00000042790(gene)|ensembl:ENSMUST00000058720(transcript)|ensembl:ENSMUST00000160699(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q8BFU3|go:"GO:0046872"(metal ion binding)|refseq:XP_011240801.1|refseq:XP_011240804.1|refseq:XP_011240805.1|refseq:XP_017168820.1|refseq:NP_848824.1 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:QAL8Wz57jqXfWUQjLeV72ah6mWM10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P98203 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8399145|uniprotkb:Q924L3|uniprotkb:Q924L2|uniprotkb:Q8BQ36|uniprotkb:Q6PGJ6|uniprotkb:Q8C3U7|uniprotkb:Q924L4|uniprotkb:Q924L5|intact:MINT-4123053|uniprotkb:Q8BRF2|ensembl:ENSMUSP00000159426|ensembl:ENSMUSP00000159427 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:arvc_mouse(display_long)|uniprotkb:Arvcf(gene name)|psi-mi:Arvcf(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001258957.1|refseq:NP_001258960.1|refseq:NP_001258958.1|refseq:NP_258435.2|refseq:NP_001258959.1|refseq:NP_001258961.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028444|mint:P98203|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000118669(gene)|ensembl:ENSMUST00000239534(transcript)|ensembl:ENSMUST00000239535(transcript) - - comment:mint|function:Involved in protein-protein interactions at adherens junctions comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:7brlaZI4C07uNoqAPYZBkW2SWDg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99LD4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8313949|uniprotkb:Q8C2J7|intact:MINT-1869858|uniprotkb:B0QZT1 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:csn1_mouse(display_long)|uniprotkb:Gps1(gene name)|psi-mi:Gps1(display_short)|uniprotkb:Cops1(gene name synonym)|uniprotkb:Csn1(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 1(gene name synonym)|uniprotkb:G protein pathway suppressor 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 interpro:IPR033008|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|reactome:R-MMU-5696394|reactome:R-MMU-6781823|reactome:R-MMU-8856825|reactome:R-MMU-8951664|reactome:R-MMU-9013422|interpro:IPR019585|interpro:IPR036390|mint:Q99LD4|interpro:IPR000717(Proteasome component region PCI) - - comment:mint|function:"Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein-and mitogen-activated protein kinase-mediated signal transduction" comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:sd18zpeaq9Xs/VDNTz0ATO5HkkU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9D0D5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8393665|uniprotkb:Q544T0|intact:MINT-4136705|ensembl:ENSMUSP00000023525 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:t2ea_mouse(display_long)|uniprotkb:Gtf2e1(gene name)|psi-mi:Gtf2e1(display_short)|uniprotkb:Transcription initiation factor IIE subunit alpha(gene name synonym)|uniprotkb:General transcription factor IIE 56 kDa subunit(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_083088.1|refseq:XP_006522722.1|ensembl:ENSMUSG00000022828(gene)|ensembl:ENSMUST00000023525(transcript)|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005673"(transcription factor TFIIE complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR002853(Transcription factor TFIIE, alpha subunit)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR017919|interpro:IPR021600|interpro:IPR024550|interpro:IPR039997|mint:Q9D0D5|reactome:R-MMU-674695|reactome:R-MMU-6807505|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042 - - comment:mint|function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:kTXej5NOWd87f6e4x/ewNbtg5AE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9JLJ2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8312000|intact:MINT-4087568 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:al9a1_mouse(display_long)|uniprotkb:Aldh9a1(gene name)|psi-mi:Aldh9a1(display_short)|uniprotkb:Aldehyde dehydrogenase family 9 member A1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0019145"(aminobutyraldehyde dehydrogenase activity)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043176"(amine binding)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0047105"(4-trimethylammoniobutyraldehyde dehydrogenase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051289"(protein homotetramerization)|reactome:R-MMU-71262|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|refseq:NP_064377.2|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR029510|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:Q9JLJ2 - - comment:mint|function:Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:uXxF6XbI0zoKyywn5/zT0h4gtdU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P07309 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8345356|intact:MINT-1855774|ensembl:ENSMUSP00000074783 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:tthy_mouse(display_long)|uniprotkb:Ttr(gene name)|psi-mi:Ttr(display_short)|uniprotkb:Prealbumin(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_038725.1|dip:DIP-29726N|ensembl:ENSMUSG00000061808(gene)|ensembl:ENSMUST00000075312(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P07309|rcsb pdb:2QPF|reactome:R-MMU-2453902|reactome:R-MMU-3000171|reactome:R-MMU-6798695|reactome:R-MMU-975634 - - comment:mint|function:Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:hkkz23yVTIqCYtItyjSDzZabauw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99LH1 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8458780|uniprotkb:B1ASC3|intact:MINT-4103943|uniprotkb:Q8BIF8|ensembl:ENSMUSP00000030684 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:nog2_mouse(display_long)|uniprotkb:Gnl2(gene name)|psi-mi:Gnl2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_663527.2|ensembl:ENSMUSG00000028869(gene)|ensembl:ENSMUST00000030684(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q99LH1 - - function:GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:FFvgh3mmfxqi/0sV4eNXMbU+GdU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3USH5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8387273|uniprotkb:Q8CCZ1|intact:MINT-4115248|ensembl:ENSMUSP00000062413 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:sfswa_mouse(display_long)|uniprotkb:Sfrs8(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 8(gene name synonym)|uniprotkb:Srsf8(gene name synonym)|uniprotkb:Suppressor of white apricot protein homolog(gene name synonym)|uniprotkb:Swap(gene name synonym)|uniprotkb:Sfswap(gene name)|psi-mi:Sfswap(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_758480.2|ensembl:ENSMUSG00000029439(gene)|ensembl:ENSMUST00000053737(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000061(SWAP/Surp)|interpro:IPR019147|interpro:IPR035967|interpro:IPR040397|mint:Q3USH5 - - comment:"fragmentation type: fragment"|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:tD+aKGuqHqhvOcAPhO0QeBcTEpk10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BVY0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8339028|uniprotkb:Q8K235|intact:MINT-4112887|ensembl:ENSMUSP00000113431 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rl1d1_mouse(display_long)|uniprotkb:Rsl1d1(gene name)|psi-mi:Rsl1d1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_079822.1|ensembl:ENSMUSG00000005846(gene)|ensembl:ENSMUST00000119953(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:Q8BVY0 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:dvktZG7E05exciHtyzN7bS+rRvc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q61136 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8340757|uniprotkb:Q9CTT0|intact:MINT-1751441|uniprotkb:Q8BND8|uniprotkb:Q9CTL9|uniprotkb:Q8R4Y5|uniprotkb:O88378|uniprotkb:B2RUN6|intact:MINT-8174118|ensembl:ENSMUSP00000077019|ensembl:ENSMUSP00000152654 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:prp4b_mouse(display_long)|uniprotkb:Prpf4b(gene name)|psi-mi:Prpf4b(display_short)|uniprotkb:Cbp143(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:Pre-mRNA protein kinase(gene name synonym)|uniprotkb:Prp4h(gene name synonym)|uniprotkb:Prp4k(gene name synonym)|uniprotkb:Prp4m(gene name synonym)|uniprotkb:Prpk(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_038858.2|refseq:XP_017170914.1|refseq:XP_017170915.1|refseq:XP_017170916.1|refseq:XP_017170917.1|refseq:XP_017170918.1|refseq:XP_017170919.1|refseq:XP_017170920.1|refseq:XP_017170921.1|refseq:XP_017170922.1|refseq:XP_017170923.1|refseq:XP_017170924.1|refseq:XP_017170925.1|refseq:XP_017170926.1|ensembl:ENSMUSG00000021413(gene)|ensembl:ENSMUST00000077853(transcript)|ensembl:ENSMUST00000222509(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q61136 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:NExsvbfNo81zTqoFaEY82b8YsKA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P97825 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8314326|ensembl:ENSMUSP00000021083|intact:MINT-4106360 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:jupi1_mouse(display_long)|uniprotkb:Jpt1(gene name)|psi-mi:Jpt1(display_short)|uniprotkb:Hematological and neurological expressed 1 protein(gene name synonym)|uniprotkb:Hn1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000020737(gene)|ensembl:ENSMUST00000021083(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031965"(nuclear membrane)|interpro:IPR033335|mint:P97825|refseq:NP_032284.1 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:pCqs0IYbgaphiiQ8oS8xorMxwjQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q80XC2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8316834|ensembl:ENSMUSP00000082011|ensembl:ENSMUSP00000133128|uniprotkb:Q8BMD4|uniprotkb:Q8BX33|intact:MINT-4113315 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:trm61_mouse(display_long)|uniprotkb:"mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A"(gene name synonym)|uniprotkb:Trm61(gene name synonym)|uniprotkb:"tRNA(m1A58)-methyltransferase subunit TRMT61A"(gene name synonym)|uniprotkb:Trmt61a(gene name)|psi-mi:Trmt61a(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000060950(gene)|ensembl:ENSMUST00000084947(transcript)|ensembl:ENSMUST00000168338(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016429"("tRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0031515"("tRNA (m1A) methyltransferase complex")|go:"GO:0061953"("mRNA (adenine-N1-)-methyltransferase activity")|go:"GO:0080009"(mRNA methylation)|interpro:IPR014816(tRNA methyltransferase complex GCD14 subunit)|interpro:IPR029063|mint:Q80XC2|refseq:NP_001093262.1|refseq:NP_796348.2|refseq:NP_001093263.1 - - function:"Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA"|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Bss94NyGQpUWfSVDbn/B9/xyuZA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P83870 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8388008|intact:MINT-4107454|uniprotkb:Q9UH06|uniprotkb:Q3TQX7|ensembl:ENSMUSP00000023117 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:phf5a_mouse(display_long)|uniprotkb:Phf5a(gene name)|psi-mi:Phf5a(display_short)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_081013.1|ensembl:ENSMUSG00000061360(gene)|ensembl:ENSMUST00000023117(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:P83870|reactome:R-MMU-72163 - - comment:mint|function:Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha. Also involved in pre-mRNA splicing comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9D0F3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-7597453|intact:MINT-1858436|ensembl:ENSMUSP00000113326|ensembl:ENSMUSP00000158495|ensembl:ENSMUSP00000040140 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:lman1_mouse(display_long)|uniprotkb:Lman1(gene name)|psi-mi:Lman1(display_short)|uniprotkb:Ergic53(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001165533.1|refseq:NP_081676.1|ensembl:ENSMUSG00000041891(gene)|ensembl:ENSMUST00000048260(transcript)|ensembl:ENSMUST00000120461(transcript)|ensembl:ENSMUST00000236866(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:Q9D0F3|reactome:R-MMU-204005|reactome:R-MMU-5694530|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423 - - comment:mint|function:Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:nv9a22cWi98b4bSjwzaQUNkiMzc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9CWN7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8573234|ensembl:ENSMUSP00000003219|ensembl:ENSMUSP00000125638|intact:MINT-8174096|uniprotkb:Q3TJG9 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cno11_mouse(display_long)|uniprotkb:Cnot11(gene name)|psi-mi:Cnot11(display_short)|uniprotkb:D1Bwg0212e(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 interpro:IPR019312|reactome:R-MMU-429947|reactome:R-MMU-6804115|ensembl:ENSMUSG00000003135(gene)|ensembl:ENSMUST00000003219(transcript)|ensembl:ENSMUST00000161515(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|refseq:NP_082319.1 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:P2w7IMUCr7M/u6xX5ikMZ1LmI+M10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99KG3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8340093|intact:UNK-5410659|uniprotkb:Q3UKI8|intact:UNK-5414103|intact:MINT-4123810|uniprotkb:Q8BTP8|uniprotkb:Q80U75|uniprotkb:Q3TIY0|intact:UNK-5405339|uniprotkb:Q3U5B8|ensembl:ENSMUSP00000068188|ensembl:ENSMUSP00000111032 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rbm10_mouse(display_long)|uniprotkb:Rbm10(gene name)|psi-mi:Rbm10(display_short)|uniprotkb:Kiaa0122(gene name synonym)|uniprotkb:RNA-binding motif protein 10(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001161247.1|refseq:NP_001161248.1|refseq:NP_663602.1|refseq:XP_006527681.1|ensembl:ENSMUSG00000031060(gene)|ensembl:ENSMUST00000064911(transcript)|ensembl:ENSMUST00000115374(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:Q99KG3 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:DDTFfKjoPE0TZLRlwIVJq1XzbBQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3URU2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8321320|uniprotkb:Q6GQS0|uniprotkb:Q3TQ69|uniprotkb:Q9QX53|uniprotkb:Q61138|intact:MINT-4105070|uniprotkb:Q5EBP7|uniprotkb:Q80U47|uniprotkb:Q8R5N0|uniprotkb:O54978|ensembl:ENSMUSP00000050750 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:peg3_mouse(display_long)|uniprotkb:Peg3(gene name)|psi-mi:Peg3(display_short)|uniprotkb:Kiaa0287(gene name synonym)|uniprotkb:Pw1(gene name synonym)|uniprotkb:ASF-1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_032843.2|refseq:XP_017177520.1|refseq:XP_017177521.1|ensembl:ENSMUSG00000002265(gene)|ensembl:ENSMUST00000051209(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q3URU2 - - comment:mint|function:Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Plays a role in regulating maternal behavior and offspring growth comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Un3V5tx4sJLRTLyl+TxxMILswHM10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P24788 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8341078|intact:MINT-4090174|uniprotkb:Q7TST4|uniprotkb:Q8BP53|uniprotkb:Q61399|uniprotkb:Q3UI03|ensembl:ENSMUSP00000070527|ensembl:ENSMUSP00000101225 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cd11b_mouse(display_long)|uniprotkb:Cdk11b(gene name)|psi-mi:Cdk11b(display_short)|uniprotkb:Cdc2l1(gene name synonym)|uniprotkb:Cdk11(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 1(gene name synonym)|uniprotkb:Cell division protein kinase 11(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001334237.1|refseq:XP_011248481.1|refseq:NP_031687.2|refseq:XP_017175418.1|refseq:XP_017175419.1|refseq:XP_006538571.1|refseq:XP_006538574.1|refseq:XP_017175422.1|refseq:XP_017175423.1|ensembl:ENSMUSG00000029062(gene)|ensembl:ENSMUST00000067081(transcript)|ensembl:ENSMUST00000105600(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:P24788|reactome:R-MMU-380270 - - comment:mint|function:Acts as a negative regulator of the normal cell cycle progression. In vitro, this protein kinase has been shown to phosphorylate a number of substrates, including histone h1, casein, and galactosyltransferase. May function in regulating proliferation by the phosphorylation and subsequent plasma membrane targeting of galactosyltransferase comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:ZSpex1pgx216ZntR9dgjyX85zFQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q5SFM8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8387650|uniprotkb:Q8C2X5|uniprotkb:E9QM85|uniprotkb:Q7TQK8|intact:MINT-4114843|uniprotkb:Q8C9A5|uniprotkb:Q6ZPT9|ensembl:ENSMUSP00000158063 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rbm27_mouse(display_long)|uniprotkb:Rbm27(gene name)|psi-mi:Rbm27(display_short)|uniprotkb:Kiaa1311(gene name synonym)|uniprotkb:RNA-binding motif protein 27(gene name synonym)|uniprotkb:Peri-implantation stem cell protein 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_766214.2|refseq:XP_006525926.1|ensembl:ENSMUSG00000024491(gene)|ensembl:ENSMUST00000236240(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034451|interpro:IPR035979|mint:Q5SFM8 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:QAKqFX6736IjVhKA1SDcIHyN64k10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q923D5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8339190|uniprotkb:O88539|uniprotkb:Q8VDI0|uniprotkb:Q3UMD8|intact:MINT-125895|ensembl:ENSMUSP00000112213 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:wbp11_mouse(display_long)|uniprotkb:Wbp11(gene name)|psi-mi:Wbp11(display_short)|uniprotkb:Sipp1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_068360.4|refseq:XP_017177182.1|ensembl:ENSMUSG00000030216(gene)|ensembl:ENSMUST00000116514(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q923D5|reactome:R-MMU-72163 - - comment:mint|function:May play a role in the regulation of pre-mRNA processing comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:YCcyxBraQLnCIceR99oIZ6pAyXQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q02614 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8458227|intact:MINT-4119830|uniprotkb:Q8VDJ5|ensembl:ENSMUSP00000114844 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:s30bp_mouse(display_long)|uniprotkb:Sap30bp(gene name)|psi-mi:Sap30bp(display_short)|uniprotkb:Hcngp(gene name synonym)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_065229.2|ensembl:ENSMUSG00000020755(gene)|ensembl:ENSMUST00000140991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q02614 - - comment:mint|function:"Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival (By similarity). May be involved in the regulation of beta-2-microglobulin genes" comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:WI5iNVKs+YvBfV1rwLaMcUwddEs10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P61458 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8316318|ensembl:ENSMUSP00000020298|intact:MINT-4107515|uniprotkb:Q9D930|uniprotkb:P70519|uniprotkb:P80095 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:phs_mouse(display_long)|uniprotkb:Pcbd1(gene name)|psi-mi:Pcbd1(display_short)|uniprotkb:Dcoh(gene name synonym)|uniprotkb:Pcbd(gene name synonym)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000020098(gene)|ensembl:ENSMUST00000020298(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61458|reactome:R-MMU-8964208|refseq:NP_079549.1 - - function:Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:VcZMOj2T/TRbWjDRJw2fPhkeBIo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9Z0H1 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8387585|intact:MINT-4089262|ensembl:ENSMUSP00000025170 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:wdr46_mouse(display_long)|uniprotkb:Wdr46(gene name)|psi-mi:Wdr46(display_short)|uniprotkb:Bing4(gene name synonym)|uniprotkb:WD repeat-containing protein BING4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_065628.1|ensembl:ENSMUSG00000024312(gene)|ensembl:ENSMUST00000025170(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012952(BING4, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040315|mint:Q9Z0H1|reactome:R-MMU-6791226 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:7SvE5MXPVeYg0xVUrDyUgRYAKUs10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q0VBL3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8572651|intact:EBI-11518552|intact:EBI-9989873|intact:EBI-16360075|uniprotkb:A0PJG5|uniprotkb:Q3THK4|uniprotkb:Q3TLX0|uniprotkb:Q571M7|uniprotkb:Q66JP8|uniprotkb:Q6PGG1|uniprotkb:Q7TT82|ensembl:ENSMUSP00000054424|intact:MINT-8174194 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rbm15_mouse(display_long)|uniprotkb:Kiaa4257(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym)|uniprotkb:Ott1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:Rbm15(gene name)|psi-mi:Rbm15(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001039272.1|ensembl:ENSMUSG00000048109(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|ensembl:ENSMUST00000061772(transcript)|go:"GO:0048536"(spleen development)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979 - - comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:09qhcrNbUkJFdyi2RiYw3SDXVW410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P09813 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8319889|intact:MINT-1855567|uniprotkb:Q61317|uniprotkb:Q3UKX6|ensembl:ENSMUSP00000005824|ensembl:ENSMUSP00000106951|ensembl:ENSMUSP00000106952|ensembl:ENSMUSP00000106953 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:apoa2_mouse(display_long)|uniprotkb:Apoa2(gene name)|psi-mi:Apoa2(display_short)|uniprotkb:Apolipoprotein A2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001292478.1|refseq:NP_001292479.1|refseq:NP_001292514.1|refseq:NP_038502.2|ensembl:ENSMUSG00000005681(gene)|ensembl:ENSMUST00000005824(transcript)|ensembl:ENSMUST00000111319(transcript)|ensembl:ENSMUST00000111320(transcript)|ensembl:ENSMUST00000111321(transcript)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034370"(triglyceride-rich lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0046340"(diacylglycerol catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0060695"(negative regulation of cholesterol transporter activity)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR006801("Apolipoprotein A-II (ApoA-II)")|interpro:IPR036172|mint:P09813|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-8963901|reactome:R-MMU-975634 - - function:"May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism"|comment:mint|function:"Defects in Apoa2 are the cause of senescence accelerated mouse (SAM), the senile amyloid is a mutated apolipoprotein A-II" comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:H/Lp6cVxnlotT1P/cwAAPljEYiU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q923G2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8586840|ensembl:ENSMUSP00000021405|intact:MINT-4611351|uniprotkb:Q3TT30 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rpab3_mouse(display_long)|uniprotkb:Polr2h(gene name)|psi-mi:Polr2h(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000021018(gene)|ensembl:ENSMUST00000021405(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-76061|reactome:R-MMU-76066|reactome:R-MMU-76071|reactome:R-MMU-77075|reactome:R-MMU-9018519|refseq:NP_663607.1 - - function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9CQV6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-7942066|uniprotkb:Q3U9W5|intact:UNK-5540201|uniprotkb:Q9D1R0|ensembl:ENSMUSP00000034270 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:mlp3b_mouse(display_long)|uniprotkb:Map1lc3b(gene name)|psi-mi:Map1lc3b(display_short)|uniprotkb:Map1alc3(gene name synonym)|uniprotkb:Map1lc3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_080436.1|dip:DIP-61580N|go:"GO:0012505"(endomembrane system)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044754"(autolysosome)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:5WRD|rcsb pdb:5YIQ|rcsb pdb:5YIS|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8854214|reactome:R-MMU-8934903|reactome:R-MMU-9664873|go:"GO:0009267"(cellular response to starvation)|ensembl:ENSMUSG00000031812(gene)|ensembl:ENSMUST00000034270(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding) - - comment:mint|function:"Probably involved in formation of autophagosomal vacuoles (autophagosomes)" comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:i7XYb/AU0h/HmGBNN0hFhJJ/GEw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3TKY6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-8458317|uniprotkb:Q9CXT1|uniprotkb:Q8BG42|uniprotkb:Q8R158|intact:MINT-4125785|intact:MINT-4085044|ensembl:ENSMUSP00000022228 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cwc27_mouse(display_long)|uniprotkb:Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog(gene name synonym)|uniprotkb:Sdccag10(gene name synonym)|uniprotkb:Cwc27(gene name)|psi-mi:Cwc27(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_080348.1|ensembl:ENSMUSG00000021715(gene)|ensembl:ENSMUST00000022228(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|interpro:IPR044666|mint:Q3TKY6|reactome:R-MMU-72163 - - function:PPIases accelerate the folding of proteins|comment:mint comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:KkVREDaArVpsTZFeyWSmtZBezfo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q6PR54 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2312621|uniprotkb:Q6T8D9|uniprotkb:Q7TPD8|uniprotkb:Q8BTU2|uniprotkb:Q8C408|uniprotkb:Q9CS77 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rif1_mouse(display_long)|uniprotkb:Rif1(gene name)|psi-mi:Rif1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:XP_011237438.1|refseq:NP_780447.4|reactome:R-MMU-5693571|refseq:XP_006498240.1|dip:DIP-54907N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:OQUxpLkl6IvIwG8+hQpd84hztJs10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3TSG4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889399|ensembl:ENSMUSP00000049116|uniprotkb:Q80US0|uniprotkb:Q8BKB9|uniprotkb:Q8BKC1 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:alkb5_mouse(display_long)|uniprotkb:Alkylated DNA repair protein alkB homolog 5(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5(gene name synonym)|uniprotkb:Alkbh5(gene name)|psi-mi:Alkbh5(display_short)|uniprotkb:Abh5(gene name synonym)|uniprotkb:Ofoxd(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035553"(oxidative single-stranded RNA demethylation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1990931"(mRNA N6-methyladenosine dioxygenase activity)|interpro:IPR032860|interpro:IPR037151|reactome:R-MMU-73943|interpro:IPR027450|ensembl:ENSMUSG00000042650(gene)|ensembl:ENSMUST00000044250(transcript)|refseq:NP_766531.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:qRYv+3G/XaHCr9+ahoeBZ4OfaUE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F6XUR8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889388|ensembl:ENSMUSP00000118234 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f6xur8_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000150217(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Gp3nKBWIUoU9M1CSXUVrfiISq6E10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9CWW7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-11057018|ensembl:ENSMUSP00000025444 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cxxc1_mouse(display_long)|uniprotkb:Cxxc1(gene name)|psi-mi:Cxxc1(display_short)|uniprotkb:Cgbp(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:Pccx1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_083144.1|ensembl:ENSMUSG00000024560(gene)|ensembl:ENSMUST00000025444(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR022056|interpro:IPR037869 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:F8l4yKXUMeRz4IzsTFgLRlA3I7E10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:J3QPB5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889374|ensembl:ENSMUSP00000137180 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:j3qpb5_mouse(display_long)|uniprotkb:Transmembrane protein 48(gene name synonym)|uniprotkb:Ndc1(gene name)|psi-mi:Ndc1(display_short)|uniprotkb:Tmem48(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028614(gene)|ensembl:ENSMUST00000149366(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR019049 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:iSpg3dwHR/BPg655fiu0Uiquop410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1B0GRM4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889357|ensembl:ENSMUSP00000147584 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1b0grm4_mouse(display_long)|uniprotkb:Ppfia3(gene name)|psi-mi:Ppfia3(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000003863(gene)|ensembl:ENSMUST00000210248(transcript)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030440|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:WJrjo6mt0M6k++ECstEzmE7WdRE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q80XC6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889334|ensembl:ENSMUSP00000021596|uniprotkb:E9QKV8|uniprotkb:Q8R3D7|uniprotkb:Q99LT9 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:nrde2_mouse(display_long)|uniprotkb:Protein NRDE2 homolog(gene name synonym)|uniprotkb:Nrde2(gene name)|psi-mi:Nrde2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000021179(gene)|ensembl:ENSMUST00000021596(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016246"(RNA interference)|go:"GO:0016607"(nuclear speck)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:1902369"(negative regulation of RNA catabolic process)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013633(Protein of unknown function DUF1740)|refseq:NP_001277232.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:DESniu0z3kpks+BB1GADRSzHFFc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:B7ZCU2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889314|ensembl:ENSMUSP00000120769 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:b7zcu2_mouse(display_long)|uniprotkb:Abi1(gene name)|psi-mi:Abi1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUST00000153931(transcript)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR036028|ensembl:ENSMUSG00000058835(gene)|refseq:XP_006497682.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:4Sj+bGzWI40tU7yb2Iyqf35vBJQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0G2JFW6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889303|ensembl:ENSMUSP00000143333 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0g2jfw6_mouse(display_long)|uniprotkb:Rprd2(gene name)|psi-mi:Rprd2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028106(gene)|ensembl:ENSMUST00000200164(transcript)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Kc4Fihl9PIOZ8ZUjBwwAnFkNIxY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1B0GSR3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889291|ensembl:ENSMUSP00000148039 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1b0gsr3_mouse(display_long)|uniprotkb:Srek1(gene name)|psi-mi:Srek1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000032621(gene)|ensembl:ENSMUST00000211322(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034192|interpro:IPR035979 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:xdyYRFTMJ1+89swtngkqgRp8u5s10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A087WP81 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889274|ensembl:ENSMUSP00000139668 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a087wp81_mouse(display_long)|uniprotkb:Uchl5(gene name)|psi-mi:Uchl5(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000018189(gene)|ensembl:ENSMUST00000185493(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:mVSw+syqV3nkUkgtkdIyIufmqXE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q60848 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-3043887|ensembl:ENSMUSP00000025965|uniprotkb:Q497T3|uniprotkb:Q8VDZ1|uniprotkb:Q9CYV7 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:hells_mouse(display_long)|uniprotkb:Hells(gene name)|psi-mi:Hells(display_short)|uniprotkb:Lsh(gene name synonym)|uniprotkb:Pasg(gene name synonym)|uniprotkb:Proliferation-associated SNF2-like protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000025001(gene)|ensembl:ENSMUST00000025965(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001655"(urogenital system development)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044753|mint:Q60848|refseq:NP_032260.2|refseq:XP_006526762.1|dip:DIP-43735N - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:rxUxEmjFSksq7JWhJEaA4Xeo+XY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:G3UZM6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889267|ensembl:ENSMUSP00000134556 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:g3uzm6_mouse(display_long)|uniprotkb:Ube4b(gene name)|psi-mi:Ube4b(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028960(gene)|ensembl:ENSMUST00000174343(transcript) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:EUPFt5BVliVHXs/UQmDZ+UOp/1w10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q5F2D9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889251|ensembl:ENSMUSP00000082018 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q5f2d9_mouse(display_long)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)|uniprotkb:DN-491F10.4-006(orf name) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000084954(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:LejdkDBZj9ZgaeOD9SnWbZNtmSU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2AB60 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889229|ensembl:ENSMUSP00000102642 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2ab60_mouse(display_long)|uniprotkb:Fmnl1(gene name)|psi-mi:Fmnl1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000055805(gene)|ensembl:ENSMUST00000107027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027657|interpro:IPR042201|interpro:IPR043592|go:"GO:0031267"(small GTPase binding)|refseq:NP_062653.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:xYXPMkvJyG58HZGvfd+uxfyv0c410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2AG47 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889215|ensembl:ENSMUSP00000116332 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2ag47_mouse(display_long)|uniprotkb:Maged2(gene name)|psi-mi:Maged2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000025268(gene)|ensembl:ENSMUST00000147152(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR028810|interpro:IPR037445 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:qZ3xWVIHV0ZNGV4n3jcMsokz38010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99K01 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6909991|uniprotkb:Q3TCL3|uniprotkb:Q3TN13|uniprotkb:Q8BMK9|uniprotkb:Q8BW02|uniprotkb:Q8BW51|uniprotkb:Q8BZZ4|uniprotkb:Q9DC25 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:pdxd1_mouse(display_long)|uniprotkb:Pdxdc1(gene name)|psi-mi:Pdxdc1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001277946.1|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:NP_001034622.1|refseq:NP_444411.2|mint:Q99K01 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:MqmpBly7g1D61y1iA3hjz3zyWlU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8R307 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2527788|uniprotkb:Q8BGV6|uniprotkb:Q8BZX6|uniprotkb:Q8C126|ensembl:ENSMUSP00000036915 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:vps18_mouse(display_long)|uniprotkb:Vps18(gene name)|psi-mi:Vps18(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000034216(gene)|ensembl:ENSMUST00000037280(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005884"(actin filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033263"(CORVET complex)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|refseq:NP_758473.3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:ZYg55QUg3B3pBixwuFUqaAsB+W410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q5SWP3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889194|ensembl:ENSMUSP00000049490|uniprotkb:Q6I6F5 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:nacad_mouse(display_long)|uniprotkb:Nacad(gene name)|psi-mi:Nacad(display_short)|uniprotkb:Kiaa0363(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000041073(gene)|ensembl:ENSMUST00000045713(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR041907|interpro:IPR044034|refseq:NP_001075121.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:LkJNr58SveLApOUaAvJ8LHA0r9410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9PZM4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889162|ensembl:ENSMUSP00000126352 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:chd2_mouse(display_long)|uniprotkb:ATP-dependent helicase CHD2(gene name synonym)|uniprotkb:Chd2(gene name)|psi-mi:Chd2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|ensembl:ENSMUSG00000078671(gene)|ensembl:ENSMUST00000169922(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007517"(muscle organ development)|go:"GO:0042393"(histone binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|refseq:NP_001074814.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:XXvHsKICgKq/47dKQ/dEnT7rtkw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P51807 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-642797|uniprotkb:Q5M8S6|ensembl:ENSMUSP00000137171|ensembl:ENSMUSP00000135978|ensembl:ENSMUSP00000090644|ensembl:ENSMUSP00000127990 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:dylt1_mouse(display_long)|uniprotkb:T-complex testis-specific protein 1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)|uniprotkb:Tctex1(gene name synonym)|uniprotkb:Tctex-1(gene name synonym)|uniprotkb:Dynlt1(gene name)|psi-mi:Dynlt1(display_short)|uniprotkb:Activator of G-protein signaling 2(gene name synonym)|uniprotkb:Tctel1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001160099.1|refseq:NP_001160101.1|refseq:NP_001160102.1|refseq:NP_033368.1|ensembl:ENSMUST00000092966(transcript)|ensembl:ENSMUST00000169415(transcript)|ensembl:ENSMUST00000179554(transcript)|ensembl:ENSMUST00000179569(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051301"(cell division)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0099503"(secretory vesicle)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|mint:P51807|rcsb pdb:5WI4|reactome:R-MMU-6798695|go:"GO:0030742"(GTP-dependent protein binding)|ensembl:ENSMUSG00000000579(gene)|ensembl:ENSMUSG00000092074(gene)|ensembl:ENSMUSG00000095677(gene)|ensembl:ENSMUSG00000096255(gene)|refseq:XP_017172676.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:fn6QN4J3aA++93iJwG3rFDjPBvM10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0R4J0V5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889137|ensembl:ENSMUSP00000071200 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0r4j0v5_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000071213(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:KfnZ+IlJ5iJaiRD7+iAkvqAn4N810090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:B7ZC90 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889130|ensembl:ENSMUSP00000120555 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:b7zc90_mouse(display_long)|uniprotkb:Crocc(gene name)|psi-mi:Crocc(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000040860(gene)|ensembl:ENSMUST00000144196(transcript) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Vwim33Cn5RF+qND8ag/Bxs3oJqE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2A4P0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889101|ensembl:ENSMUSP00000037251 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:dhx8_mouse(display_long)|uniprotkb:DEAH box protein 8(gene name synonym)|uniprotkb:Dhx8(gene name)|psi-mi:Dhx8(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000034931(gene)|ensembl:ENSMUST00000039152(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR003029(S1, RNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR022967|interpro:IPR027417|interpro:IPR044762|refseq:NP_659080.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:C0mMzP+VZdXGdQRwoupD4zKKMBE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q61048 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889069|ensembl:ENSMUSP00000022601|uniprotkb:Q3TUU8|uniprotkb:Q8K1Z9|uniprotkb:Q9CS45 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:wbp4_mouse(display_long)|uniprotkb:Formin-binding protein 21(gene name synonym)|uniprotkb:WW domain-containing-binding protein 4(gene name synonym)|uniprotkb:Wbp4(gene name)|psi-mi:Wbp4(display_short)|uniprotkb:Fbp21(gene name synonym)|uniprotkb:Fnbp21(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000022023(gene)|ensembl:ENSMUST00000022601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013085(Zinc finger, U1-C type)|interpro:IPR036020|interpro:IPR036236|interpro:IPR040023|reactome:R-MMU-72163|refseq:NP_061235.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:2DmC6lQt2rb6vFAWb75bCej4NAs10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9QQ10 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889046|ensembl:ENSMUSP00000046129 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e9qq10_mouse(display_long)|uniprotkb:Akap9(gene name)|psi-mi:Akap9(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000040407(gene)|ensembl:ENSMUST00000044492(transcript)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0043025"(neuronal cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR019528|interpro:IPR028745|go:"GO:0007165"(signal transduction)|refseq:NP_919444.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:DVFWrRRmBa0lX2s+smI/Y5rufEQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9Q5G3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2553152|uniprotkb:Q80V30|uniprotkb:Q99PT8|ensembl:ENSMUSP00000034815 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:kif23_mouse(display_long)|uniprotkb:Kif23(gene name)|psi-mi:Kif23(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_077207.3|ensembl:ENSMUSG00000032254(gene)|ensembl:ENSMUST00000034815(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-68884|reactome:R-MMU-983189|go:"GO:0045171"(intercellular bridge) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:734bTofHqm+vN9dUUJ4YgpULwak10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BLN5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889020|ensembl:ENSMUSP00000046856|uniprotkb:Q8BVJ4|uniprotkb:Q8K307 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:lss_mouse(display_long)|uniprotkb:2,3-epoxysqualene--lanosterol cyclase(gene name synonym)|uniprotkb:Oxidosqualene--lanosterol cyclase(gene name synonym)|uniprotkb:Lss(gene name)|psi-mi:Lss(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000033105(gene)|ensembl:ENSMUST00000048678(transcript)|go:"GO:0000250"(lanosterol synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016104"(triterpenoid biosynthetic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042300"(beta-amyrin synthase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002365(Terpene synthase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR018333|interpro:IPR032697|reactome:R-MMU-191273|interpro:IPR032696|refseq:NP_666118.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:+UD+Wwctk7pMAqMSoB9N6uQXrSE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1W2P7Q6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26889001|ensembl:ENSMUSP00000151722 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1w2p7q6_mouse(display_long)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:Xpot(gene name)|psi-mi:Xpot(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|ensembl:ENSMUSG00000034667(gene)|ensembl:ENSMUST00000218004(transcript)|go:"GO:0000049"(tRNA binding)|refseq:NP_001074525.1|refseq:XP_006514267.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:03iNPXIB/SUpaobbTGk3P/mGDE010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:O88967 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-11518380|uniprotkb:Q7TNN5|ensembl:ENSMUSP00000028117 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ymel1_mouse(display_long)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:Yme1l1(gene name)|psi-mi:Yme1l1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_038799.1|ensembl:ENSMUSG00000026775(gene)|ensembl:ENSMUST00000028117(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:O88967|reactome:R-MMU-8949664|go:"GO:0007005"(mitochondrion organization) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:r9+ZzXnqp1squdeZ4KAr6YVU29c10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9Z2H5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-774482|uniprotkb:Q3U3L1|uniprotkb:Q3UHP7|uniprotkb:Q80U34|uniprotkb:Q8K204 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e41l1_mouse(display_long)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4(gene name synonym)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Kiaa0338(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001278049.1|refseq:NP_001278051.1|refseq:NP_001278052.1|refseq:NP_001006665.1|refseq:NP_038538.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|interpro:IPR035963|mint:Q9Z2H5|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-MMU-399719|reactome:R-MMU-6794361 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Lu31NnWhI356njHUtKbBlaO6nWE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q80YR4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888977|ensembl:ENSMUSP00000157172|uniprotkb:Q6KAT0|uniprotkb:Q8R3S1 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:zn598_mouse(display_long)|uniprotkb:Zinc finger protein 598(gene name synonym)|uniprotkb:Znf598(gene name)|psi-mi:Znf598(display_short)|uniprotkb:Zfp598(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000041130(gene)|ensembl:ENSMUST00000234956(transcript)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041888|interpro:IPR044288|refseq:NP_001335160.1|refseq:NP_898972.1|refseq:XP_006524062.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:TpR6gzowHno1cvOicPGhYPKw5vc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9JHP7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888947|ensembl:ENSMUSP00000064500|uniprotkb:Q8BPU6|uniprotkb:Q8C528|uniprotkb:Q8R591|uniprotkb:Q9D8P1 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:plgt2_mouse(display_long)|uniprotkb:Endoplasmic reticulum resident protein 58(gene name synonym)|uniprotkb:KDEL motif-containing protein 1(gene name synonym)|uniprotkb:Protein O-xylosyltransferase POGLUT2(gene name synonym)|uniprotkb:Poglut2(gene name)|psi-mi:Poglut2(display_short)|uniprotkb:Ep58(gene name synonym)|uniprotkb:Kdelc1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000026047(gene)|ensembl:ENSMUST00000065767(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0012505"(endomembrane system)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0035251"(UDP-glucosyltransferase activity)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0140561"(EGF-domain serine glucosyltransferase activity)|go:"GO:0140562"(EGF-domain serine xylosyltransferase activity)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR006598(Lipopolysaccharide-modifying protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|refseq:NP_076134.1|refseq:XP_006496352.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:vWU3jGyjfDIkWsui4WqwFbgLkss10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0J9YVJ6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888928|ensembl:ENSMUSP00000144690 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0j9yvj6_mouse(display_long)|uniprotkb:Pnkp(gene name)|psi-mi:Pnkp(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000002963(gene)|ensembl:ENSMUST00000201882(transcript)|go:"GO:0006281"(DNA repair)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046404"(polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR006550(Polynucleotide kinase 3-phosphatase)|interpro:IPR006551(DNA 3-phosphatase)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013954(Polynucleotide kinase 3 phosphatase, central region)|interpro:IPR023214|interpro:IPR027417|interpro:IPR036412|interpro:IPR041388 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:jjy8z/MC4Eyv0v2ZWp9VVQEWdtI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9Z2D0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888897|ensembl:ENSMUSP00000059894|uniprotkb:A6H6P1|uniprotkb:Q80XL4 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:mtmr9_mouse(display_long)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 9(gene name synonym)|uniprotkb:Mtmr9(gene name)|psi-mi:Mtmr9(display_short)|uniprotkb:Mtmr3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000035078(gene)|ensembl:ENSMUST00000058679(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029021|interpro:IPR030564|reactome:R-MMU-1660499|refseq:NP_808262.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:mryZ+MGp3c27kR+CLQ0DvNJfSC410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8CFE2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888881|ensembl:ENSMUSP00000047235 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:hpf1_mouse(display_long)|uniprotkb:Hpf1(gene name)|psi-mi:Hpf1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000038005(gene)|ensembl:ENSMUST00000037190(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0042393"(histone binding)|go:"GO:0072572"(poly-ADP-D-ribose binding)|go:"GO:0090734"(site of DNA damage)|interpro:IPR019361|rcsb pdb:6M3H|refseq:NP_082575.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:mchMaSlyqiuH3nnw8RKXLpiAlxg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q91VN6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2551902|uniprotkb:Q3U0E0|ensembl:ENSMUSP00000021956 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ddx41_mouse(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:Ddx41(gene name)|psi-mi:Ddx41(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000021494(gene)|ensembl:ENSMUST00000021956(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q91VN6|reactome:R-MMU-1834941|reactome:R-MMU-3134975|refseq:NP_598820.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:S3WFr9A6pfkQ5sHqZv/RwWUulZI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3YWC2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888871|ensembl:ENSMUSP00000112506 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3ywc2_mouse(display_long)|uniprotkb:Arl6ip4(gene name)|psi-mi:Arl6ip4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 interpro:IPR019532|ensembl:ENSMUSG00000029404(gene)|ensembl:ENSMUST00000122394(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016607"(nuclear speck) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:i3ypVkehWu5acvy2nKTr5unmHnk10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9QAS9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888841|ensembl:ENSMUSP00000110302 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e9qas9_mouse(display_long)|uniprotkb:Fmr1(gene name)|psi-mi:Fmr1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000000838(gene)|ensembl:ENSMUST00000114654(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030426"(growth cone)|go:"GO:0032433"(filopodium tip)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:iQqaxPif3BHdIEG96Ee+RUbcKQ410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F6YBV1 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888827|ensembl:ENSMUSP00000117297 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f6ybv1_mouse(display_long)|uniprotkb:Cnot3(gene name)|psi-mi:Cnot3(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000035632(gene)|ensembl:ENSMUST00000132344(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030015"(CCR4-NOT core complex)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR040168 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:t9KgQeMxwbhd+C0o+GpitRqApaU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2AAN2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888812|ensembl:ENSMUSP00000102033 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2aan2_mouse(display_long)|uniprotkb:Srp68(gene name)|psi-mi:Srp68(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000020780(gene)|ensembl:ENSMUST00000106425(transcript)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:qzBxJ3+V1ADFVWt55iV+z2uHiZc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8K2T8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-642477|uniprotkb:Q3UY97|uniprotkb:Q9CS63|uniprotkb:Q9JJ99|ensembl:ENSMUSP00000003529 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:paf1_mouse(display_long)|uniprotkb:Paf1(gene name)|psi-mi:Paf1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_062331.2|ensembl:ENSMUSG00000003437(gene)|ensembl:ENSMUST00000003529(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8K2T8|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955|reactome:R-MMU-8866654 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:1cFGAVgb19bf33BaPcIowpXT5qc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E0CY49 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888798|ensembl:ENSMUSP00000124487 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e0cy49_mouse(display_long)|uniprotkb:Asl(gene name)|psi-mi:Asl(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000025533(gene)|ensembl:ENSMUST00000161640(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004056"(argininosuccinate lyase activity)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|interpro:IPR000362(Fumarate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR022761|interpro:IPR024083 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:jP1/V/rQZ/lVWYYOYHIuleCNr4I10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:B2RQC2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888774|ensembl:ENSMUSP00000053955 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ubp42_mouse(display_long)|uniprotkb:Deubiquitinating enzyme 42(gene name synonym)|uniprotkb:Ubiquitin thioesterase 42(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 42(gene name synonym)|uniprotkb:Usp42(gene name)|psi-mi:Usp42(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000051306(gene)|ensembl:ENSMUST00000053287(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|reactome:R-MMU-5689880|refseq:NP_084025.2|refseq:XP_006504817.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Z5oBwWDzXPJwF1xNZv2xUoQYm+U10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8K3K7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888752|ensembl:ENSMUSP00000028286 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:plcb_mouse(display_long)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 2(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase beta(gene name synonym)|uniprotkb:Agpat2(gene name)|psi-mi:Agpat2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000026922(gene)|ensembl:ENSMUST00000028286(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008544"(epidermis development)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0042493"|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR004552(1-acyl-sn-glycerol-3-phosphate acyltransferase)|reactome:R-MMU-1483166|reactome:R-MMU-6798695|refseq:NP_080488.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:N5gd6/f50fQ7F643DUpGjbNDMOA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:G3V019 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888740|ensembl:ENSMUSP00000134723 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:g3v019_mouse(display_long)|uniprotkb:Trmt1(gene name)|psi-mi:Trmt1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000001909(gene)|ensembl:ENSMUST00000136423(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:n2byIq5d0ld+a9rZwd7xRevLzKE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8R2K3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888720|ensembl:ENSMUSP00000110427|ensembl:ENSMUSP00000113563|ensembl:ENSMUSP00000114082 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q8r2k3_mouse(display_long)|uniprotkb:Ssbp1(gene name)|psi-mi:Ssbp1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000029911(gene)|ensembl:ENSMUST00000114779(transcript)|ensembl:ENSMUST00000117411(transcript)|ensembl:ENSMUST00000121360(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006260"(DNA replication)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_001273592.1|refseq:NP_001273593.1|refseq:NP_997633.1|refseq:XP_006506393.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:zTXeqFvxrS9FGyVIwvjEtj7m8s410090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3Z6S3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888712|ensembl:ENSMUSP00000122335 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3z6s3_mouse(display_long)|uniprotkb:Tssc4(gene name)|psi-mi:Tssc4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000045752(gene)|ensembl:ENSMUST00000147995(transcript)|interpro:IPR029338 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:0qx4vyQ/E7BabioYRBoEAFyAoB010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99MS8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-11707427|uniprotkb:Q3U5Q9|uniprotkb:Q9R0B5|ensembl:ENSMUSP00000159326 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:tpgs1_mouse(display_long)|uniprotkb:Gm16517(gene name synonym)|uniprotkb:Tpgs1(gene name)|psi-mi:Tpgs1(display_short)|uniprotkb:Gtrgeo22(gene name synonym)|uniprotkb:p32(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_683736.1|ensembl:ENSMUSG00000020308(gene)|ensembl:ENSMUST00000239401(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018095"(protein polyglutamylation)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0031514"(motile cilium)|go:"GO:0045202"(synapse)|go:"GO:0051648"(vesicle localization)|go:"GO:0070740"(tubulin-glutamic acid ligase activity)|interpro:IPR039235|mint:Q99MS8|go:"GO:0030425"(dendrite) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:CNNi+XO6HFs87Nv1puXz45++/OA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3Z1R9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888700|ensembl:ENSMUSP00000121979 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3z1r9_mouse(display_long)|uniprotkb:Cops4(gene name)|psi-mi:Cops4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUST00000146476(transcript)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR037754|interpro:IPR040134|ensembl:ENSMUSG00000035297(gene) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:hsApoHWwP6FX7jvGrWn0CGo1wFg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0R4J214 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888687|ensembl:ENSMUSP00000126804 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0r4j214_mouse(display_long)|uniprotkb:Rbm26(gene name)|psi-mi:Rbm26(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000022119(gene)|ensembl:ENSMUST00000172122(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034861|interpro:IPR035979|interpro:IPR039511 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:YlOjnSGdrQP9EvrjXar7++XeMeg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8CIL4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888676|ensembl:ENSMUSP00000034465|uniprotkb:Q3UNZ3|uniprotkb:Q9CZF4 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ca131_mouse(display_long) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000031984(gene)|ensembl:ENSMUST00000034465(transcript)|go:"GO:0005694"(chromosome)|interpro:IPR027973|refseq:NP_079891.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:X/f92WDjLWh7cKoI0ofXnCWzygI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0N4SW65 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888665|ensembl:ENSMUSP00000144875|ensembl:ENSMUSP00000145392 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0n4sw65_mouse(display_long)|uniprotkb:Cmas(gene name)|psi-mi:Cmas(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000030282(gene)|ensembl:ENSMUST00000133248(transcript)|ensembl:ENSMUST00000144920(transcript)|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|interpro:IPR029044 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:+xoCZKyvb6BUj/yk5PIIZ+7kPig10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9D198 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-9987953|ensembl:ENSMUSP00000030622 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:syf2_mouse(display_long)|uniprotkb:Syf2(gene name)|psi-mi:Syf2(display_short)|uniprotkb:Cbpin(gene name synonym)|uniprotkb:Gcipip(gene name synonym)|uniprotkb:CCNDBP1-interactor(gene name synonym)|uniprotkb:mp29(gene name synonym)|uniprotkb:p29(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028821(gene)|ensembl:ENSMUST00000030622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0048568"(embryonic organ development)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR013260(mRNA splicing factor SYF2)|reactome:R-MMU-72163|go:"GO:0005634"(nucleus)|refseq:NP_081056.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:6hFH1DWkMC+jlbtEApKhgZdhbNw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:V9GWX3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888653|ensembl:ENSMUSP00000138873 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:v9gwx3_mouse(display_long)|uniprotkb:Rpap1(gene name)|psi-mi:Rpap1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000034032(gene)|ensembl:ENSMUST00000184294(transcript)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR013929(RNA polymerase II-associated protein 1, C-terminal)|interpro:IPR013930(RNA polymerase II-associated protein 1, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039913 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:HbPIj77nMOIc8DJIfscCvzKIbsY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8CGZ0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2366446|uniprotkb:Q8K291|uniprotkb:Q8VCD2 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cherp_mouse(display_long)|uniprotkb:Cherp(gene name)|psi-mi:Cherp(display_short)|uniprotkb:Scaf6(gene name synonym)|uniprotkb:SR-related CTD-associated factor 6(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_613051.3|interpro:IPR008942(ENTH/VHS)|interpro:IPR000467(D111/G-patch)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR000061(SWAP/Surp)|interpro:IPR035967|interpro:IPR039037|mint:Q8CGZ0|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|reactome:R-MMU-72163 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:mPEKMUbwYs/8ryr9RBLWjNF0nnk10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A8Y5G7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888643|ensembl:ENSMUSP00000122906 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a8y5g7_mouse(display_long)|uniprotkb:Pold2(gene name)|psi-mi:Pold2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000020471(gene)|ensembl:ENSMUST00000153995(transcript)|go:"GO:0006260"(DNA replication)|interpro:IPR024826|interpro:IPR040663 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:X/Z6uELByxlczBYaEJ8zqCYWCIo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P31324 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-455340|uniprotkb:Q3UTZ1|uniprotkb:Q80ZM4|uniprotkb:Q8BRZ7|uniprotkb:B1B199|ensembl:ENSMUSP00000003079|ensembl:ENSMUSP00000039797 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:kap3_mouse(display_long)|uniprotkb:Prkar2b(gene name)|psi-mi:Prkar2b(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_035288.2|refseq:XP_006515077.1|dip:DIP-31571N|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31324|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:4WBB|rcsb pdb:4X6Q|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-432040|reactome:R-MMU-442720|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-983231|ensembl:ENSMUSG00000002997(gene)|ensembl:ENSMUST00000003079(transcript)|ensembl:ENSMUST00000036497(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097546"(ciliary base)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0097338"(response to clozapine)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:/d/0NSAnglWjmZAcQUn6ATpbJnE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3Z5G4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888635|ensembl:ENSMUSP00000117207 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3z5g4_mouse(display_long)|uniprotkb:Zfr(gene name)|psi-mi:Zfr(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000022201(gene)|ensembl:ENSMUST00000128475(transcript)|interpro:IPR036236 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:lIye6hyMx2A1P1Z8/spq8lS6eUk10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3ULB0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-11518009|ensembl:ENSMUSP00000035201 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q3ulb0_mouse(display_long)|uniprotkb:Rbm6(gene name)|psi-mi:Rbm6(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_035381.2|refseq:NP_083445.1|ensembl:ENSMUSG00000032582(gene)|ensembl:ENSMUST00000035201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028806|interpro:IPR034123|interpro:IPR034125|interpro:IPR035617|interpro:IPR035979|interpro:IPR041591|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:XP_017168705.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:r1QvEg6dsSI00ROyjVfYKiZLJrE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2A481 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888597|ensembl:ENSMUSP00000104885 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2a481_mouse(display_long)|uniprotkb:Zmynd8(gene name)|psi-mi:Zmynd8(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000039671(gene)|ensembl:ENSMUST00000109262(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:95n/Voi/FzAokFl2t7KkSlGrPLQ10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F7AB82 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888583|ensembl:ENSMUSP00000117431 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f7ab82_mouse(display_long)|uniprotkb:Reps1(gene name)|psi-mi:Reps1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000019854(gene)|ensembl:ENSMUST00000155892(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006898"(receptor-mediated endocytosis)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:/zaeI5RWG8NUt9Z0OwaCu+GkrqA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8K194 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888566|ensembl:ENSMUSP00000001186|uniprotkb:Q8BRA8|uniprotkb:Q9CSV0 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:snr27_mouse(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated protein 3(gene name synonym)|uniprotkb:Snrnp27(gene name)|psi-mi:Snrnp27(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000001158(gene)|ensembl:ENSMUST00000001186(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR013957(Protein of unknown function DUF1777)|reactome:R-MMU-72163|refseq:NP_079941.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:pDjrHJdJVTrC/fwicPincUMfWXE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9PX53 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888550|ensembl:ENSMUSP00000124690 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e9px53_mouse(display_long)|uniprotkb:Ppp4r1(gene name)|psi-mi:Ppp4r1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000061950(gene)|ensembl:ENSMUST00000160664(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030289"(protein phosphatase 4 complex)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031087|refseq:NP_001107603.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:uoKF7t+pYCN4A1hqu2u+UYDN9FA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9DAK9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888526|ensembl:ENSMUSP00000037417 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:php14_mouse(display_long)|uniprotkb:Phosphohistidine phosphatase 1(gene name synonym)|uniprotkb:Protein histidine phosphatase(gene name synonym)|uniprotkb:Phpt1(gene name)|psi-mi:Phpt1(display_short)|uniprotkb:Php14(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000036504(gene)|ensembl:ENSMUST00000039156(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035971"(peptidyl-histidine dephosphorylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051350"(negative regulation of lyase activity)|go:"GO:0101006"(protein histidine phosphatase activity)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000984"(negative regulation of ATP citrate synthase activity)|interpro:IPR007702(Janus/Ocnus)|interpro:IPR028441|interpro:IPR038596|refseq:NP_083569.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:XuiIeVS1wUg4M11Kxf0A6hRX9XY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q921F4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26884994|ensembl:ENSMUSP00000058308|ensembl:ENSMUSP00000139372|uniprotkb:Q3UIK6|uniprotkb:Q6IR44|uniprotkb:Q8BIP6|uniprotkb:Q91W02|uniprotkb:Q99J40 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:hnrll_mouse(display_long)|uniprotkb:Hnrnpll(gene name)|psi-mi:Hnrnpll(display_short)|uniprotkb:Hnrpll(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000024095(gene)|ensembl:ENSMUST00000061331(transcript)|ensembl:ENSMUST00000184635(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034983|interpro:IPR034985|interpro:IPR034986|interpro:IPR034987|interpro:IPR035979|rcsb pdb:1WEX|rcsb pdb:2E5I|refseq:NP_659051.3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:lAhgzoMsGpt94mumkYVy7H+PMCI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q6A0A2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-9987790|ensembl:ENSMUSP00000140993|uniprotkb:Q3TUH7|uniprotkb:Q6AZA8|uniprotkb:Q8BJP3|uniprotkb:Q8BY17 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:lar4b_mouse(display_long)|uniprotkb:Larp4b(gene name)|psi-mi:Larp4b(display_short)|uniprotkb:D13Wsu64e(gene name synonym)|uniprotkb:Kiaa0217(gene name synonym)|uniprotkb:Larp5(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001298046.1|ensembl:ENSMUSG00000033499(gene)|ensembl:ENSMUST00000188211(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|refseq:NP_766173.1|refseq:XP_006516539.1|refseq:XP_006516540.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:ApbenASAKU1pHcJSDiRwmczYTUM10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F6UFG6 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888517|ensembl:ENSMUSP00000115293 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f6ufg6_mouse(display_long)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000156461(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:07KopXLaEKyThknA2TaEjlpkJUo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1Y7VJD9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888504|ensembl:ENSMUSP00000152382 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1y7vjd9_mouse(display_long)|uniprotkb:Zc3h14(gene name)|psi-mi:Zc3h14(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000021012(gene)|ensembl:ENSMUST00000223451(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008143"("poly(A) binding")|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR040366 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:gyeiiR+VZ38IAF9SfOOW4UkFwTw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0G2JGW4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888494|ensembl:ENSMUSP00000143724 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0g2jgw4_mouse(display_long)|uniprotkb:Prpf38b(gene name)|psi-mi:Prpf38b(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000027881(gene)|ensembl:ENSMUST00000129273(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005037(PRP38) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:aifCv5vw9xTVSIui+cHfiguoRsA10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D6REG4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888482|ensembl:ENSMUSP00000117800 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d6reg4_mouse(display_long)|uniprotkb:Grhpr(gene name)|psi-mi:Grhpr(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000035637(gene)|ensembl:ENSMUST00000151631(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0051287"(NAD binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR036291 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:LwQ2Xa7/U5KhYXGvksoEiLDu8Ak10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9DC28 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6392453|ensembl:ENSMUSP00000018274|uniprotkb:Q3TZK2|uniprotkb:Q99KK4 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:kc1d_mouse(display_long)|uniprotkb:Csnk1d(gene name)|psi-mi:Csnk1d(display_short)|uniprotkb:Hckid(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000025162(gene)|ensembl:ENSMUST00000018274(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9DC28|rcsb pdb:4JJR|rcsb pdb:5X17|reactome:R-MMU-204005|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6791226|reactome:R-MMU-8854518|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|refseq:NP_620690.1|dip:DIP-47809N - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:FAsEbnos4akvB+YK6EAFbAsBtTo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8K389 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-11068840|uniprotkb:Q6PCN1|uniprotkb:A2AVA1|uniprotkb:Q6ZPL0|ensembl:ENSMUSP00000119891 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ck5p2_mouse(display_long)|uniprotkb:Cdk5rap2(gene name)|psi-mi:Cdk5rap2(display_short)|uniprotkb:CDK5 activator-binding protein C48(gene name synonym)|uniprotkb:Kiaa1633(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_666102.2|ensembl:ENSMUSG00000039298(gene)|ensembl:ENSMUST00000144099(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012943(Spindle associated)|interpro:IPR042791|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:DyXUSB0U+q7WgrdIW3HI3vjkpEo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 intact:EBI-3645152 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 - psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q80x98(display_short)|psi-mi:EBI-3645152(display_long) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 uniprotkb:Q80X98(see-also) - - no-uniprot-update: comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 - - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3YV30 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888471|ensembl:ENSMUSP00000114732 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3yv30_mouse(display_long)|uniprotkb:Grsf1(gene name)|psi-mi:Grsf1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000044221(gene)|ensembl:ENSMUST00000133532(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033106 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:/GoX69Vruw7YTN4dmj27gYhvWa010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2AR01 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888458|ensembl:ENSMUSP00000114570 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2ar01_mouse(display_long)|uniprotkb:Ppig(gene name)|psi-mi:Ppig(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000042133(gene)|ensembl:ENSMUST00000144652(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:bl3yLEI/Jz+ReyT4UrXGtI13MS010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9R1R8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888447|ensembl:ENSMUSP00000082352 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q9r1r8_mouse(display_long)|uniprotkb:Rdh11(gene name)|psi-mi:Rdh11(display_short)|uniprotkb:Ube-1b(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000066441(gene)|ensembl:ENSMUST00000085254(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:VSvgavTtwecB2n2L/pR+J1HE4gg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A087WSG5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888430|ensembl:ENSMUSP00000141036 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a087wsg5_mouse(display_long)|uniprotkb:Mnat1(gene name)|psi-mi:Mnat1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000021103(gene)|ensembl:ENSMUST00000187549(transcript)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR004575("Cdk-activating kinase assembly factor (MAT1)")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015877(Cdk-activating kinase assembly factor, MAT1)|interpro:IPR017907 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Cv0hLBjIabMRgeq70diblrXa8zY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:O88907 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A2A8V8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888419|ensembl:ENSMUSP00000101487 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a2a8v8_mouse(display_long)|uniprotkb:Srrm1(gene name)|psi-mi:Srrm1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028809(gene)|ensembl:ENSMUST00000105861(transcript)|go:"GO:0006397"(mRNA processing)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR036483|refseq:XP_006539090.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:V3Pe0APv6ZJMn2rAtnkZQI1I38s10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P26883 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6379901|ensembl:ENSMUSP00000037206|uniprotkb:Q545E9 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:fkb1a_mouse(display_long)|uniprotkb:Fkbp1a(gene name)|psi-mi:Fkbp1a(display_short)|uniprotkb:Fkbp1(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:P26883|reactome:R-MMU-166208|reactome:R-MMU-2025928|reactome:R-MMU-2173789|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSMUSG00000032966(gene)|ensembl:ENSMUST00000044011(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006936"(muscle contraction)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|refseq:NP_001289006.1|refseq:NP_001289007.1|refseq:NP_001289008.1|refseq:NP_001289009.1|dip:DIP-29707N|refseq:NP_032045.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:G3Dq41lUNMncyt6e7S8Ntwy5K3Y10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:H3BLR3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888405|ensembl:ENSMUSP00000135885 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:h3blr3_mouse(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000052997(gene)|ensembl:ENSMUST00000175991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR023318|interpro:IPR030661|interpro:IPR033127|interpro:IPR035985 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:nAiVbF9rzQ7hoptDgEJyc15taqw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8C0D7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-645598|uniprotkb:Q8C1S7|uniprotkb:Q8K3Q5|uniprotkb:Q8K3Q6|uniprotkb:Q8K3Q7|uniprotkb:Q9D7F9|ensembl:ENSMUSP00000121519 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ing4_mouse(display_long)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:Ing4(gene name)|psi-mi:Ing4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_579923.1|ensembl:ENSMUSG00000030330(gene)|ensembl:ENSMUST00000140131(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8C0D7|rcsb pdb:1WEN|rcsb pdb:1WEU|reactome:R-MMU-3214847 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:i6BnXl7FG4akcSbiC3prvkZud6k10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q6P1B9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888388|ensembl:ENSMUSP00000089590 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q6p1b9_mouse(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000024381(gene)|ensembl:ENSMUST00000091967(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030100"(regulation of endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|refseq:NP_001076803.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:HK8vdGcw4JUqxJ53Gkr0URLJZbg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9Q5K9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-647644|intact:EBI-8387264|intact:MINT-4119288|uniprotkb:E9PW44|uniprotkb:E9Q7Z8|uniprotkb:Q69Z54|uniprotkb:Q80V25|uniprotkb:Q8R5E6|ensembl:ENSMUSP00000039133 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ytdc1_mouse(display_long)|uniprotkb:Ythdc1(gene name)|psi-mi:Ythdc1(display_short)|uniprotkb:Kiaa1966(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_808348.2|refseq:NP_001334304.1|refseq:NP_001334305.1|ensembl:ENSMUSG00000035851(gene)|ensembl:ENSMUST00000038384(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048160"(primary follicle stage)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR007275(YT521-B-like protein)|mint:E9Q5K9 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:QSAdNTe3Gp42+kz7+8bzO74N9Ck10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P70333 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-4282223|ensembl:ENSMUSP00000050838|ensembl:ENSMUSP00000074483|ensembl:ENSMUSP00000108827|ensembl:ENSMUSP00000108828|ensembl:ENSMUSP00000108829|uniprotkb:Q3THV9 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:hnrh2_mouse(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001300645.1|refseq:NP_001300646.1|uniprotkb:A2BDV8(uniprot-removed-ac)|ensembl:ENSMUST00000074950(transcript)|ensembl:ENSMUST00000113202(transcript)|ensembl:ENSMUST00000113203(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P70333|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUST00000059297(transcript)|ensembl:ENSMUSG00000045427(gene)|ensembl:ENSMUST00000050331(transcript)|refseq:NP_063921.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:BKLnU/p+g6hd6joRgjXU+BO5i7o10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1L1SS95 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888373|ensembl:ENSMUSP00000149816 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1l1ss95_mouse(display_long)|uniprotkb:Elavl3(gene name)|psi-mi:Elavl3(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000003410(gene)|ensembl:ENSMUST00000215901(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR035979 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:WCbIIFjrYCGZSfNA+1et6IgB71g10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A087WP98 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888365|ensembl:ENSMUSP00000139690 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a087wp98_mouse(display_long)|uniprotkb:Ptma(gene name)|psi-mi:Ptma(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000026238(gene)|ensembl:ENSMUST00000186255(transcript)|interpro:IPR004931(Prothymosin/parathymosin) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:3EMPCb9wNTUcyaJLZalaNvXQlEI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F7B6Z5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888354|ensembl:ENSMUSP00000125640 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f7b6z5_mouse(display_long)|uniprotkb:Cpsf4(gene name)|psi-mi:Cpsf4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000029625(gene)|ensembl:ENSMUST00000160762(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041686 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:S/RzjQCEPkpeTlHXJ6trPSEos3w10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F7C265 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888344|ensembl:ENSMUSP00000122736 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f7c265_mouse(display_long)|uniprotkb:Ccdc47(gene name)|psi-mi:Ccdc47(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000078622(gene)|ensembl:ENSMUST00000125383(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|interpro:IPR012879(Protein of unknown function DUF1682) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:xMxa/LqSUPkv5njHK46YOVdcmK010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BKA3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888319|ensembl:ENSMUSP00000075488|uniprotkb:Q8R1S5|uniprotkb:Q9CW37 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:srrm4_mouse(display_long)|uniprotkb:Neural-specific serine/arginine repetitive splicing factor of 100 kDa(gene name synonym)|uniprotkb:Srrm4(gene name)|psi-mi:Srrm4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000063919(gene)|ensembl:ENSMUST00000076124(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008380"(RNA splicing)|go:"GO:0030154"(cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR029360|refseq:NP_081162.1|refseq:XP_006530519.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:sLJRwC6Ybgd3deSY5/N+2lp0H9010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1B0GRD5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888312|ensembl:ENSMUSP00000147474 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1b0grd5_mouse(display_long)|uniprotkb:Pih1d1(gene name)|psi-mi:Pih1d1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000003423(gene)|ensembl:ENSMUST00000211414(transcript) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Dw6j5nco2suUco0REKkbsuwuavg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q5U4C3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-16360097|ensembl:ENSMUSP00000082501|ensembl:ENSMUSP00000148251|uniprotkb:Q3UR01 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:sfr19_mouse(display_long)|uniprotkb:SR-related and CTD-associated factor 1(gene name synonym)|uniprotkb:Scaf1(gene name)|psi-mi:Scaf1(display_short)|uniprotkb:Sfrs19(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000038406(gene)|ensembl:ENSMUST00000085383(transcript)|ensembl:ENSMUST00000211735(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|refseq:NP_001008422.1|refseq:XP_006540884.1|refseq:XP_011249157.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:53uc4rvcetYN/+EV85AzDiULqPg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3UC65 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888297|ensembl:ENSMUSP00000077226|uniprotkb:Q80Y97|uniprotkb:Q9CSN6|uniprotkb:Q9D194|uniprotkb:Q9JJF1 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rsrp1_mouse(display_long)|uniprotkb:Rsrp1(gene name)|psi-mi:Rsrp1(display_short)|uniprotkb:D4Wsu53e(gene name synonym)|uniprotkb:MNCb-0169(orf name) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000037266(gene)|ensembl:ENSMUST00000078084(transcript)|interpro:IPR029656|refseq:NP_076154.3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:Vzym0IwcM/GXQbAXi50xuHdP0Ow10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BIQ5 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6910260|ensembl:ENSMUSP00000033609|uniprotkb:A2AEJ9|uniprotkb:A2AEK0|uniprotkb:Q8K1Y6|uniprotkb:Q9ERC2 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:cstf2_mouse(display_long)|uniprotkb:Cstf2(gene name)|psi-mi:Cstf2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001277328.1|ensembl:ENSMUSG00000031256(gene)|ensembl:ENSMUST00000033609(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:Q8BIQ5|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-77595|refseq:NP_573459.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:34MgxXRI1XsU5aMjgMnm93voyx810090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:H3BJU7 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888274|ensembl:ENSMUSP00000135131 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:h3bju7_mouse(display_long)|uniprotkb:Rho guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000177303(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0051301"(cell division)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:RLLGJiIxCak7aSxkAzC1eS2eshI10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D6RCI8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888265|ensembl:ENSMUSP00000121452|ensembl:ENSMUSP00000141982 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d6rci8_mouse(display_long)|uniprotkb:Imp4(gene name)|psi-mi:Imp4(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000026127(gene)|ensembl:ENSMUST00000137794(transcript)|ensembl:ENSMUST00000149962(transcript)|go:"GO:0006364"(rRNA processing)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR044281 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:KsmdhI++3IIr9Gdo53IvLCxPr6c10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q61749 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26611340|ensembl:ENSMUSP00000076875|uniprotkb:Q3TYW7|uniprotkb:Q61748|uniprotkb:Q8VC35 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:ei2bd_mouse(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:Eif2b4(gene name)|psi-mi:Eif2b4(display_short)|uniprotkb:Eif2b(gene name synonym)|uniprotkb:Eif2bd(gene name synonym)|uniprotkb:Jgr1a(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q61749|reactome:R-MMU-72731|ensembl:ENSMUSG00000029145(gene)|ensembl:ENSMUST00000077693(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|refseq:NP_001120827.1|refseq:NP_001120828.1|refseq:NP_034252.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:DoX84q/fy6k/K6rNNo96Xdgc8Kw10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BLD4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888237|ensembl:ENSMUSP00000038113|ensembl:ENSMUSP00000129342|ensembl:ENSMUSP00000139476|ensembl:ENSMUSP00000140364 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q8bld4_mouse(display_long)|uniprotkb:Tardbp(gene name)|psi-mi:Tardbp(display_short)|uniprotkb:TARDBP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000041459(gene)|ensembl:ENSMUST00000045180(transcript)|ensembl:ENSMUST00000165113(transcript)|ensembl:ENSMUST00000188134(transcript)|ensembl:ENSMUST00000189048(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|refseq:NP_001003898.1|refseq:NP_001003899.1|refseq:NP_001008545.1|refseq:NP_001008546.1|refseq:NP_001292354.1|refseq:NP_663531.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:heSGss99QVUIGUVcLHvLNKepn3U10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q99ME9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-4285566|uniprotkb:Q99K16|uniprotkb:Q99P78|uniprotkb:Q9CT02|ensembl:ENSMUSP00000152412 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:gtpb4_mouse(display_long)|uniprotkb:Gtpbp4(gene name)|psi-mi:Gtpbp4(display_short)|uniprotkb:Crfg(gene name synonym)|uniprotkb:Nog1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_081276.2|ensembl:ENSMUSG00000021149(gene)|ensembl:ENSMUST00000222098(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q99ME9 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:bcJx83SRfrtIzUbasVwCDleHiR010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q07646 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888210|ensembl:ENSMUSP00000129639|uniprotkb:Q792T8|uniprotkb:Q8BS88|uniprotkb:Q8K463|uniprotkb:Q99KT5 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:mest_mouse(display_long)|uniprotkb:Paternally-expressed gene 1 protein(gene name synonym)|uniprotkb:Mest(gene name)|psi-mi:Mest(display_short)|uniprotkb:Peg1(gene name synonym)|uniprotkb:121a(orf name) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000051855(gene)|ensembl:ENSMUST00000163949(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032526"(response to retinoic acid)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR029058|refseq:NP_001239221.1|refseq:NP_001239222.1|refseq:NP_032616.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:+CZGdvvHJcBCPhj/rWeNi0XIqOU10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P02469 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3YXK2 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-539539|ensembl:ENSMUSP00000092849 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:safb1_mouse(display_long)|uniprotkb:Safb(gene name)|psi-mi:Safb(display_short)|uniprotkb:Safb1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_001156772.1|ensembl:ENSMUST00000095224(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034781|interpro:IPR035979|interpro:IPR036361|mint:D3YXK2|ensembl:ENSMUSG00000071054(gene)|reactome:R-MMU-3899300 - - comment:Author screened murine library then identified protein by homology to rat. Currently no murine sequence in database. comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:wGs3hvKUEDoWR83eBl9+qv4JWzs10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A087WQE9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888200|ensembl:ENSMUSP00000140165 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a087wqe9_mouse(display_long)|uniprotkb:Asb1(gene name)|psi-mi:Asb1(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000026311(gene)|ensembl:ENSMUST00000188081(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:ejowEdxROJok9I9UhgeWPZpXkxE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9Z2U1 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-991688|ensembl:ENSMUSP00000088057 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:psa5_mouse(display_long)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)|uniprotkb:Psma5(gene name)|psi-mi:Psma5(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_036097.1|ensembl:ENSMUSG00000068749(gene)|ensembl:ENSMUST00000090569(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:Q9Z2U1|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-8951664|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:bfMG3npzVetUH1tahr2MAI4R+3g10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q3UJH4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888188|ensembl:ENSMUSP00000139179|ensembl:ENSMUSP00000159403|uniprotkb:V9GXJ4 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:q3ujh4_mouse(display_long)|uniprotkb:Rhox5(gene name)|psi-mi:Rhox5(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000095180(gene)|ensembl:ENSMUST00000184866(transcript)|ensembl:ENSMUST00000239523(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR040069|refseq:NP_032844.2 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:RwcwzD0vEJOuLg8Dc7aJDbDFmdE10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:E9Q2R8 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888179|ensembl:ENSMUSP00000129004 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:e9q2r8_mouse(display_long)|uniprotkb:Pals2(gene name)|psi-mi:Pals2(display_short)|uniprotkb:Mpp6(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000038388(gene)|ensembl:ENSMUST00000171601(transcript)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:C/DFXPJUqMXtreQB7cYWUJZ0j/w10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A1D5RLM9 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888166|ensembl:ENSMUSP00000148434 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a1d5rlm9_mouse(display_long)|uniprotkb:Polr2c(gene name)|psi-mi:Polr2c(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000031783(gene)|ensembl:ENSMUST00000212848(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036643 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:EmO5eas5hvy3oHruACKIKbGhOkc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q9D1L0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-9072184|uniprotkb:Q3TUG8|ensembl:ENSMUSP00000091835 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:chch2_mouse(display_long)|uniprotkb:Chchd2(gene name)|psi-mi:Chchd2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_077128.2|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|ensembl:ENSMUSG00000070493(gene)|ensembl:ENSMUST00000094280(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:BpP2IQDiRRk5X1lrZWyiUSB3fBc10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q60596 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-3043989|ensembl:ENSMUSP00000070995|ensembl:ENSMUSP00000146105|uniprotkb:Q3THC5|uniprotkb:Q5U435|uniprotkb:Q7TNQ5 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:xrcc1_mouse(display_long)|uniprotkb:Xrcc1(gene name)|psi-mi:Xrcc1(display_short)|uniprotkb:Xrcc-1(gene name synonym)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|ensembl:ENSMUSG00000051768(gene)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|ensembl:ENSMUST00000063249(transcript)|ensembl:ENSMUST00000205573(transcript)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:Q60596|rcsb pdb:3PC6|rcsb pdb:3PC8|rcsb pdb:3QVG|reactome:R-MMU-110381|reactome:R-MMU-5649702|reactome:R-MMU-5685939|reactome:R-MMU-6782210|go:"GO:1904877"(positive regulation of DNA ligase activity)|refseq:XP_017177620.1|refseq:NP_033558.3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:5pzUDB1Lv6Ad68MYUJXkGYTFhC810090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:F6XW22 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888155|ensembl:ENSMUSP00000120030 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:f6xw22_mouse(display_long)|uniprotkb:Prpf40b(gene name)|psi-mi:Prpf40b(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000023007(gene)|ensembl:ENSMUST00000134034(transcript)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|interpro:IPR002713(FF)|interpro:IPR036517|interpro:IPR039726 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:EMoWeBr/J+/Hbs/24Ye8exUG1bo10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:P99027 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-6261122|ensembl:ENSMUSP00000101625|ensembl:ENSMUSP00000101626|ensembl:ENSMUSP00000081474|uniprotkb:Q9CQ99|uniprotkb:Q9CZJ8|uniprotkb:Q3TKY3 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:rla2_mouse(display_long)|uniprotkb:Rplp2(gene name)|psi-mi:Rplp2(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUST00000084434(transcript)|ensembl:ENSMUST00000106003(transcript)|ensembl:ENSMUST00000106004(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0045202"(synapse)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P99027|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000025508(gene)|refseq:XP_006536292.1|refseq:NP_080296.3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:GYHP8hzpsOXoDDDnyOOBTMeIozg10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:Q8BFZ3 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-2693747|ensembl:ENSMUSP00000052086 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:actbl_mouse(display_long)|uniprotkb:Actbl2(gene name)|psi-mi:Actbl2(display_short)|uniprotkb:Kappa-actin(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 refseq:NP_780706.1|ensembl:ENSMUSG00000055194(gene)|ensembl:ENSMUST00000054716(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q8BFZ3 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:OBTnGqn28Mc9uRapk7IOxAoxbZY10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:A0A0U1RPC4 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888142|ensembl:ENSMUSP00000145924 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:a0a0u1rpc4_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000206572(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0006412"(translation)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal) - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:YIzmalDFZ6DHjPUfo5tezD9xwa010090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3UL36 uniprotkb:D3YYA0 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 intact:EBI-26888128|ensembl:ENSMUSP00000106238 psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:d3yya0_mouse(display_long)|uniprotkb:Ash2l(gene name)|psi-mi:Ash2l(display_short) psi-mi:"MI:0030"(cross-linking study) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26888124|imex:IM-28821-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 ensembl:ENSMUSG00000031575(gene)|ensembl:ENSMUST00000110608(transcript)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|interpro:IPR043136 - - - comment:"In agreement with proteomic data obtained in HEK293 cells, we confirmed that IP-MS of endogenous ARGLU1 protein from N2a cells recovered 150 unique proteins absent from our IgG control (Supplementary Table S6). Using pathway enrichment analysis, we determined that these interacting proteins were enriched for the cellular components consisting of the spliceosomal and RNA polymerase complexes (Supplementary Figure S7), demonstrating consistency between the class of binding partners identified across the two cell systems."|figure legend:ST6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2021/03/19 2021/03/19 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 rogid:zOhLNnd+OEdIoCexrPhrd6grK9M10090 - false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHX1 uniprotkb:Q9NWB6 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0663"(confocal microscopy) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-26897303|imex:IM-28821-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0016607"(nuclear speck) - - figure legend:sf3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/26 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:rFPnGMrJRJWLYQB95mfl1eIqr+Y false green fluorescent protein tag:?-? mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P26368 uniprotkb:Q9NWB6 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0663"(confocal microscopy) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-26897332|imex:IM-28821-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0016607"(nuclear speck) - - figure legend:sf3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2021/03/19 2021/03/26 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:nCXhKwfHMUCKB/J0HML1853dS8Y false green fluorescent protein tag:?-? mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9UHX1 uniprotkb:Q9NWB6 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0663"(confocal microscopy) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-26897361|imex:IM-28821-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0016607"(nuclear speck) - - figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2021/03/19 2021/03/26 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:rFPnGMrJRJWLYQB95mfl1eIqr+Y false green fluorescent protein tag:?-? mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P26368 uniprotkb:Q9NWB6 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:0663"(confocal microscopy) Magomedova et al. (2019) pubmed:30698747|imex:IM-28821 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-26897379|imex:IM-28821-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 go:"GO:0016607"(nuclear speck) - - figure legend:sf3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2021/03/19 2021/03/26 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:nCXhKwfHMUCKB/J0HML1853dS8Y false green fluorescent protein tag:?-? mcherry fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)