#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0096"(pull down)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120047|imex:IM-29327-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/11/03	2021/11/03	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	sufficient binding region:190-344	sufficient binding region:1-360|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0096"(pull down)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120055|imex:IM-29327-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/11/03	2021/11/03	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	sufficient binding region:190-344|glutathione s tranferase tag:n-n	sufficient binding region:1-360	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120074|imex:IM-29327-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Figs. 4,6, Table 2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.8x10^-6(molar)	2021/11/03	2021/11/03	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	sufficient binding region:195-212|sufficient binding region:288-304|sufficient binding region:333-351	mutation disrupting interaction strength:286-286,290-290|mutation disrupting interaction strength:286-286,337-337|sufficient binding region:1-360	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120129|imex:IM-29327-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/11/03	2021/11/03	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	flag tag:n-n	mutation disrupting interaction strength:286-286,337-337	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120165|wwpdb:6n3f|imex:IM-29327-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Table 1|comment:Only four ULM5 residues were evident.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/11/03	2021/11/08	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	sufficient binding region:333-351	sufficient binding region:260-353	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75533-1	uniprotkb:O43719	intact:EBI-15565798|ensembl:ENSP00000335321	intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699	psi-mi:o75533-1(display_long)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)	psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Loerch et al. (2019)	pubmed:30567737|imex:IM-29327	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-27120189|imex:IM-29327-11|wwpdb:6n3e	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-876542(isoform-parent)|ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)	ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/11/03	2021/11/03	rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606	rogid:PttL+7D+505QAmcHRGNsc40haPY9606	rigid:VpyF1d0IhqaFCAWGpOCPEeQAr28	false	sufficient binding region:291-297	sufficient binding region:260-353	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)