#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O28303 uniprotkb:O29760 intact:EBI-27094675|ensemblbacteria:AAB89280 intact:EBI-1035754|ensemblbacteria:AAB90747 psi-mi:pan_arcfu(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:Proteasomal ATPase(gene name synonym)|uniprotkb:Proteasome regulatory ATPase(gene name synonym)|uniprotkb:Proteasome regulatory particle(gene name synonym)|uniprotkb:AF_1976(locus name) psi-mi:psa_arcfu(display_long)|uniprotkb:psmA(gene name)|psi-mi:psmA(display_short)|uniprotkb:AF_0490(locus name)|uniprotkb:20S proteasome alpha subunit(gene name synonym)|uniprotkb:Proteasome core protein PsmA(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Majumder et al. (2019) pubmed:30559193|imex:IM-29271 taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27094671|imex:IM-29271-1|wwpdb:6HE8|emdb:EMD-0212|wwpdb:6HED|emdb:EMD-0216|wwpdb:6HEC|emdb:EMD-0215|wwpdb:6HEA|emdb:EMD-0214|wwpdb:6HE9|emdb:EMD-0213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB89280(transcript)|ensemblbacteria:AF_1976(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043335"(protein unfolding)|refseq:WP_010879468.1|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:6HE4|rcsb pdb:6HE5|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR041569|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR023501|interpro:IPR027417|interpro:IPR032501 interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1J2P|rcsb pdb:1J2Q|interpro:IPR019982|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|rcsb pdb:6HE5|rcsb pdb:6HE7|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|ensemblbacteria:AAB90747(transcript)|ensemblbacteria:AF_0490(gene)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|refseq:WP_010877997.1|interpro:IPR029055 - - - figure legend:Fig 1, Fig S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/09/28 2021/09/28 rogid:bU1pnDZPeIQRNWAb+UCMlJRw4XY224325 rogid:vPCbkuqqbeMI7T4/3cD2JFpLEng224325 rigid:6kqgMHx56BpVRwJj24rC3a3GYVo false - - 6 14 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O28303 uniprotkb:Q9P996 intact:EBI-27094675|ensemblbacteria:AAB89280 intact:EBI-1035761|uniprotkb:O29769|ensemblbacteria:AAB90757 psi-mi:pan_arcfu(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:Proteasomal ATPase(gene name synonym)|uniprotkb:Proteasome regulatory ATPase(gene name synonym)|uniprotkb:Proteasome regulatory particle(gene name synonym)|uniprotkb:AF_1976(locus name) psi-mi:psb_arcfu(display_long)|uniprotkb:psmB(gene name)|psi-mi:psmB(display_short)|uniprotkb:AF_0481(locus name)|uniprotkb:20S proteasome beta subunit(gene name synonym)|uniprotkb:Proteasome core protein PsmB(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Majumder et al. (2019) pubmed:30559193|imex:IM-29271 taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27094671|imex:IM-29271-1|wwpdb:6HE8|emdb:EMD-0212|wwpdb:6HED|emdb:EMD-0216|wwpdb:6HEC|emdb:EMD-0215|wwpdb:6HEA|emdb:EMD-0214|wwpdb:6HE9|emdb:EMD-0213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB89280(transcript)|ensemblbacteria:AF_1976(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043335"(protein unfolding)|refseq:WP_010879468.1|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:6HE4|rcsb pdb:6HE5|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR041569|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR023501|interpro:IPR027417|interpro:IPR032501 interpro:IPR019983|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|rcsb pdb:1J2Q|rcsb pdb:6HE5|rcsb pdb:6HE7|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|ensemblbacteria:AAB90757(transcript)|ensemblbacteria:AF_0481(gene)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|interpro:IPR029055 - - - figure legend:Fig 1, Fig S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/09/28 2021/09/28 rogid:bU1pnDZPeIQRNWAb+UCMlJRw4XY224325 rogid:hcC31UmOGcgIcTcB2oMcHc7sgmQ224325 rigid:6kqgMHx56BpVRwJj24rC3a3GYVo false - sufficient binding region:11-213 6 14 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O28303 uniprotkb:O28303 intact:EBI-27094675|ensemblbacteria:AAB89280 intact:EBI-27094675|ensemblbacteria:AAB89280 psi-mi:pan_arcfu(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:Proteasomal ATPase(gene name synonym)|uniprotkb:Proteasome regulatory ATPase(gene name synonym)|uniprotkb:Proteasome regulatory particle(gene name synonym)|uniprotkb:AF_1976(locus name) psi-mi:pan_arcfu(display_long)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:Proteasomal ATPase(gene name synonym)|uniprotkb:Proteasome regulatory ATPase(gene name synonym)|uniprotkb:Proteasome regulatory particle(gene name synonym)|uniprotkb:AF_1976(locus name) psi-mi:"MI:0410"(3D electron microscopy) Majumder et al. (2019) pubmed:30559193|imex:IM-29271 taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27094741|imex:IM-29271-3|wwpdb:6HE4|emdb:EMD-0209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB89280(transcript)|ensemblbacteria:AF_1976(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043335"(protein unfolding)|refseq:WP_010879468.1|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:6HE4|rcsb pdb:6HE5|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR041569|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR023501|interpro:IPR027417|interpro:IPR032501 ensemblbacteria:AAB89280(transcript)|ensemblbacteria:AF_1976(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043335"(protein unfolding)|refseq:WP_010879468.1|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:6HE4|rcsb pdb:6HE5|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR041569|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR023501|interpro:IPR027417|interpro:IPR032501 - - - figure legend:Fig 1, Fig S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/09/28 2021/09/28 rogid:bU1pnDZPeIQRNWAb+UCMlJRw4XY224325 rogid:bU1pnDZPeIQRNWAb+UCMlJRw4XY224325 rigid:QNEm8QpSmHJuc4qcOiEMLXfzKrQ false - - 6 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q9P996 uniprotkb:O29760 intact:EBI-1035761|uniprotkb:O29769|ensemblbacteria:AAB90757 intact:EBI-1035754|ensemblbacteria:AAB90747 psi-mi:psb_arcfu(display_long)|uniprotkb:psmB(gene name)|psi-mi:psmB(display_short)|uniprotkb:AF_0481(locus name)|uniprotkb:20S proteasome beta subunit(gene name synonym)|uniprotkb:Proteasome core protein PsmB(gene name synonym) psi-mi:psa_arcfu(display_long)|uniprotkb:psmA(gene name)|psi-mi:psmA(display_short)|uniprotkb:AF_0490(locus name)|uniprotkb:20S proteasome alpha subunit(gene name synonym)|uniprotkb:Proteasome core protein PsmA(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Majumder et al. (2019) pubmed:30559193|imex:IM-29271 taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") taxid:224325(arcfu)|taxid:224325("Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-27094761|wwpdb:6he7|wwpdb:6he5|emdb:EMD-0210|emdb:EMD-0211|imex:IM-29271-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019983|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|rcsb pdb:1J2Q|rcsb pdb:6HE5|rcsb pdb:6HE7|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|ensemblbacteria:AAB90757(transcript)|ensemblbacteria:AF_0481(gene)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|interpro:IPR029055 interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1J2P|rcsb pdb:1J2Q|interpro:IPR019982|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|rcsb pdb:6HE5|rcsb pdb:6HE7|rcsb pdb:6HE8|rcsb pdb:6HE9|rcsb pdb:6HEA|rcsb pdb:6HEC|rcsb pdb:6HED|ensemblbacteria:AAB90747(transcript)|ensemblbacteria:AF_0490(gene)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|refseq:WP_010877997.1|interpro:IPR029055 - - - figure legend:Fig 1, Fig S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/09/28 2021/09/28 rogid:hcC31UmOGcgIcTcB2oMcHc7sgmQ224325 rogid:vPCbkuqqbeMI7T4/3cD2JFpLEng224325 rigid:Z7V64kv5YidK5WU2j9GIDOmtaq0 false sufficient binding region:11-213 - 14 14 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)