#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q811T9 uniprotkb:Q91VR7 intact:EBI-2298259|uniprotkb:Q7TQ21|uniprotkb:Q8CF87|uniprotkb:Q8CF88|uniprotkb:Q8CHP1|uniprotkb:Q8CHP2|ensembl:ENSMUSP00000095914|ensembl:ENSMUSP00000112410 intact:EBI-2933755|ensembl:ENSMUSP00000029128|uniprotkb:A2AVS1|uniprotkb:Q9DC74 psi-mi:disc1_mouse(display_long)|uniprotkb:Disc1(gene name)|psi-mi:Disc1(display_short) psi-mi:mlp3a_mouse(display_long)|uniprotkb:Map1lc3a(gene name)|psi-mi:Map1lc3a(display_short)|uniprotkb:Autophagy-related protein LC3 A(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 A(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 1(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 A(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2019) pubmed:30488644|imex:IM-29004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26990402|imex:IM-29004-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011246690.1|refseq:NP_777278.2|refseq:NP_777279.2|dip:DIP-54914N|ensembl:ENSMUSG00000043051(gene)|ensembl:ENSMUST00000098311(transcript)|ensembl:ENSMUST00000118942(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|rcsb pdb:5YI4|rcsb pdb:6IRR ensembl:ENSMUSG00000027602(gene)|ensembl:ENSMUST00000029128(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0044754"(autolysosome)|go:"GO:0045202"(synapse)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q91VR7|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|go:"GO:0015630"(microtubule cytoskeleton)|refseq:NP_080011.1 - - - figure legend:fig. 2d|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2021/05/04 2021/06/10 rogid:UfsMePjEeOVJHilw8WbAmeBkQ3g10090 rogid:qtZ3YM26FhxTs/gW+KFMllsVhn410090 rigid:bqqVjTJxQwQt/2lIjZMbvsH8wfU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q811T9 uniprotkb:Q91VR7 intact:EBI-2298259|uniprotkb:Q7TQ21|uniprotkb:Q8CF87|uniprotkb:Q8CF88|uniprotkb:Q8CHP1|uniprotkb:Q8CHP2|ensembl:ENSMUSP00000095914|ensembl:ENSMUSP00000112410 intact:EBI-2933755|ensembl:ENSMUSP00000029128|uniprotkb:A2AVS1|uniprotkb:Q9DC74 psi-mi:disc1_mouse(display_long)|uniprotkb:Disc1(gene name)|psi-mi:Disc1(display_short) psi-mi:mlp3a_mouse(display_long)|uniprotkb:Map1lc3a(gene name)|psi-mi:Map1lc3a(display_short)|uniprotkb:Autophagy-related protein LC3 A(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 A(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 1(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 A(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2019) pubmed:30488644|imex:IM-29004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26990406|imex:IM-29004-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011246690.1|refseq:NP_777278.2|refseq:NP_777279.2|dip:DIP-54914N|ensembl:ENSMUSG00000043051(gene)|ensembl:ENSMUST00000098311(transcript)|ensembl:ENSMUST00000118942(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|rcsb pdb:5YI4|rcsb pdb:6IRR ensembl:ENSMUSG00000027602(gene)|ensembl:ENSMUST00000029128(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010288"(response to lead ion)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0044754"(autolysosome)|go:"GO:0045202"(synapse)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q91VR7|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8934903|go:"GO:0015630"(microtubule cytoskeleton)|refseq:NP_080011.1 - - - figure legend:fig. 2d|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2021/05/04 2021/06/10 rogid:UfsMePjEeOVJHilw8WbAmeBkQ3g10090 rogid:qtZ3YM26FhxTs/gW+KFMllsVhn410090 rigid:bqqVjTJxQwQt/2lIjZMbvsH8wfU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)