#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BT04	uniprotkb:Q92997	intact:EBI-750341|uniprotkb:Q6PJY0|uniprotkb:Q9H613|uniprotkb:B2RD86|uniprotkb:B5MDH0|ensembl:ENSP00000313309	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:fuzzy_human(display_long)|uniprotkb:FUZ(gene name)|psi-mi:FUZ(display_short)|uniprotkb:FY(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maziuk et al. (2018)	pubmed:30026307|imex:IM-28750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26657545|imex:IM-28750-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165408.1|refseq:NP_079405.2|ensembl:ENSG00000010361(gene)|ensembl:ENST00000313777(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042995"(cell projection)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090301"(negative regulation of neural crest formation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000314"(negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation)|interpro:IPR026069|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-5610787	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Figure EV1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/02/17	2021/02/17	rogid:sr6bwiQro4kujjfBp/tpHm6XNkM9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rigid:I0nOa/iiucOTawX+14kLAuTbD0A	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BT04	uniprotkb:Q92997	intact:EBI-750341|uniprotkb:Q6PJY0|uniprotkb:Q9H613|uniprotkb:B2RD86|uniprotkb:B5MDH0|ensembl:ENSP00000313309	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:fuzzy_human(display_long)|uniprotkb:FUZ(gene name)|psi-mi:FUZ(display_short)|uniprotkb:FY(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Maziuk et al. (2018)	pubmed:30026307|imex:IM-28750	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-26657595|imex:IM-28750-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165408.1|refseq:NP_079405.2|ensembl:ENSG00000010361(gene)|ensembl:ENST00000313777(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042995"(cell projection)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090301"(negative regulation of neural crest formation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000314"(negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation)|interpro:IPR026069|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-HSA-5610787	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Figure EV1E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/02/17	2021/02/17	rogid:sr6bwiQro4kujjfBp/tpHm6XNkM9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rigid:I0nOa/iiucOTawX+14kLAuTbD0A	false	green fluorescent protein tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)