#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8N3C0 uniprotkb:Q8N9N2-2 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-10962548|ensembl:ENSP00000320461|ensembl:ENSP00000378377|ensembl:ENSP00000500935 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:q8n9n2-2(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26956851|imex:IM-28893-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) intact:EBI-10268317(isoform-parent)|ensembl:ENSG00000138303(gene)|ensembl:ENST00000317126(transcript)|ensembl:ENST00000394919(transcript)|ensembl:ENST00000672957(transcript)|uniprotkb:Q8N9N2-2(isoform-parent) - - - figure legend:Fig. 1A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/04/09 2021/04/26 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:sGov7EA3emkJI5up3uvaKRzuixU9606 rigid:Y3EIPDBAapmw1ywYnMEMSzUsrWw false - ha tag:?-?|necessary binding region:1-53|sufficient binding region:1-243 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3C0 uniprotkb:Q9H1I8 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26956857|imex:IM-28893-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/04/09 2021/04/20 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rigid:8RzCvjeDifK6HzKdUrrD12Icy6g false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3C0 uniprotkb:Q8N9N2 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-10268317|uniprotkb:Q9Y307|uniprotkb:Q5SW06|uniprotkb:Q5SW07|uniprotkb:Q96EI8|ensembl:ENSP00000339404|ensembl:ENSP00000378373 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:ascc1_human(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26956869|imex:IM-28893-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) refseq:NP_001185727.1|refseq:NP_001185728.1|refseq:NP_001185729.1|ensembl:ENSG00000138303(gene)|ensembl:ENST00000342444(transcript)|ensembl:ENST00000394915(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR004088(K Homology, type 1)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR009210(Predicted eukaryotic LigT)|interpro:IPR019510|interpro:IPR036612|reactome:R-HSA-112126|refseq:XP_006717936.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/04/09 2021/04/20 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:WfbfIpzdDj8dd1Ez1PbcIy2tnSA9606 rigid:zOxTMcGCfgA3XfYYavSRHhssm2k false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3C0 uniprotkb:Q8N9N2-2 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-10962548|ensembl:ENSP00000320461|ensembl:ENSP00000378377|ensembl:ENSP00000500935 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:q8n9n2-2(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:"MI:0096"(pull down) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26956894|imex:IM-28893-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) intact:EBI-10268317(isoform-parent)|ensembl:ENSG00000138303(gene)|ensembl:ENST00000317126(transcript)|ensembl:ENST00000394919(transcript)|ensembl:ENST00000672957(transcript)|uniprotkb:Q8N9N2-2(isoform-parent) - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/04/09 2021/04/26 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:sGov7EA3emkJI5up3uvaKRzuixU9606 rigid:Y3EIPDBAapmw1ywYnMEMSzUsrWw false his tag:n-n|sufficient binding region:401-2202 glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N3C0 uniprotkb:Q9H1I8 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:"MI:0096"(pull down) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26956937|imex:IM-28893-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/04/09 2021/04/20 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rigid:8RzCvjeDifK6HzKdUrrD12Icy6g false his tag:n-n|necessary binding region:401-2202 glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N9N2-2 uniprotkb:Q9H1I8 intact:EBI-10962548|ensembl:ENSP00000320461|ensembl:ENSP00000378377|ensembl:ENSP00000500935 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 psi-mi:q8n9n2-2(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26956987|imex:IM-28893-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-10268317(isoform-parent)|ensembl:ENSG00000138303(gene)|ensembl:ENST00000317126(transcript)|ensembl:ENST00000394919(transcript)|ensembl:ENST00000672957(transcript)|uniprotkb:Q8N9N2-2(isoform-parent) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 - - - figure legend:Fig. 1D|comment:Interaction not observed in ASCC3 knockout cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma) - 2021/04/09 2021/04/26 rogid:sGov7EA3emkJI5up3uvaKRzuixU9606 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rigid:/b7UTlV+efcq6G1BWipZ5UydfzI false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N9N2-2 uniprotkb:Q8N3C0 intact:EBI-10962548|ensembl:ENSP00000320461|ensembl:ENSP00000378377|ensembl:ENSP00000500935 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:q8n9n2-2(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26956987|imex:IM-28893-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-10268317(isoform-parent)|ensembl:ENSG00000138303(gene)|ensembl:ENST00000317126(transcript)|ensembl:ENST00000394919(transcript)|ensembl:ENST00000672957(transcript)|uniprotkb:Q8N9N2-2(isoform-parent) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) - - - figure legend:Fig. 1D|comment:Interaction not observed in ASCC3 knockout cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma) - 2021/04/09 2021/04/26 rogid:sGov7EA3emkJI5up3uvaKRzuixU9606 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:/b7UTlV+efcq6G1BWipZ5UydfzI false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N3C0 uniprotkb:Q9H1I8 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26957017|imex:IM-28893-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 go:"GO:0005634"(nucleus) - - figure legend:Fig. 2C|comment:Interaction not observed in ASCC1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2021/04/09 2021/04/20 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rigid:8RzCvjeDifK6HzKdUrrD12Icy6g false - ha tag:?-? - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9H1I8 uniprotkb:Q8N3C0 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26957157|imex:IM-28893-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) go:"GO:0005634"(nucleus) - - figure legend:Fig. 4E|comment:Interaction not observed in ASCC1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2021/04/09 2021/04/26 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:/b7UTlV+efcq6G1BWipZ5UydfzI false ha tag:?-? - - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9H1I8 uniprotkb:Q8N9N2-2 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 intact:EBI-10962548|ensembl:ENSP00000320461|ensembl:ENSP00000378377|ensembl:ENSP00000500935 psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:q8n9n2-2(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26957157|imex:IM-28893-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 intact:EBI-10268317(isoform-parent)|ensembl:ENSG00000138303(gene)|ensembl:ENST00000317126(transcript)|ensembl:ENST00000394919(transcript)|ensembl:ENST00000672957(transcript)|uniprotkb:Q8N9N2-2(isoform-parent) go:"GO:0005634"(nucleus) - - figure legend:Fig. 4E|comment:Interaction not observed in ASCC1-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2021/04/09 2021/04/26 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rogid:sGov7EA3emkJI5up3uvaKRzuixU9606 rigid:/b7UTlV+efcq6G1BWipZ5UydfzI false ha tag:?-? necessary binding region:244-357|mutation disrupting interaction strength:179-179,181-181,279-279,277-277 - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9H1I8 uniprotkb:Q8N3C0 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Soll et al. (2018) pubmed:29997253|imex:IM-28893 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26957106|imex:IM-28893-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) - - - figure legend:Fig. 2E|comment:"Cells were treated with methyl methanesulfonate (CHEBI:25255). Less ASCC3 was coimmunoprecipitated with ASCC2 in ASCC1 knockout cells than in WT cells upon MMS treatment/alkylation damage"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-pc3)|taxid:9606(Human PC3 Caucasian prostate adenocarcinoma) - 2021/04/09 2021/04/26 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:8RzCvjeDifK6HzKdUrrD12Icy6g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)