#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-27051089	uniprotkb:Q8TEX9-1	-	intact:EBI-27051042|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:h3 histone tail(display_short)|psi-mi:EBI-27051089(display_long)	psi-mi:q8tex9-1(display_long)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Yoon et al. (2018)	imex:IM-29189|pubmed:29408485	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-27019117|wwpdb:5XBK|imex:IM-29189-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|intact:EBI-395967(isoform-parent)	-	-	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/03/30	2021/09/02	rogid:cLhrE1NgzPvga5vIVD8ObXYntg08355	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rigid:mOEmbHY9Y5kSohMwsxx9P+usQpM	false	-	binding-associated region:668-1081	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9Y294	uniprotkb:P62799	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-302085|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6AZG5	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:h4_xenla(display_long)	psi-mi:"MI:0031"(protein cross-linking with a bifunctional reagent)	Yoon et al. (2018)	imex:IM-29189|pubmed:29408485	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27051058|imex:IM-29189-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F	go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1AOI|rcsb pdb:1KX3|rcsb pdb:1KX4|rcsb pdb:1KX5|rcsb pdb:1M18|rcsb pdb:1M19|rcsb pdb:1M1A|rcsb pdb:1P34|rcsb pdb:1P3A|rcsb pdb:1P3B|rcsb pdb:1P3F|rcsb pdb:1P3G|rcsb pdb:1P3I|rcsb pdb:1P3K|rcsb pdb:1P3L|rcsb pdb:1P3M|rcsb pdb:1P3O|rcsb pdb:1P3P|rcsb pdb:1S32|rcsb pdb:5BSA|rcsb pdb:5CP6|rcsb pdb:5DNM|rcsb pdb:5DNN|rcsb pdb:5E5A|rcsb pdb:5F99|rcsb pdb:5HQ2|rcsb pdb:5KGF|rcsb pdb:5MLU|rcsb pdb:5NL0|rcsb pdb:5O9G|rcsb pdb:5OMX|rcsb pdb:5ONG|rcsb pdb:5ONW|rcsb pdb:5OXV|rcsb pdb:5OY7|rcsb pdb:5X0X|rcsb pdb:5X0Y|rcsb pdb:5XF6|rcsb pdb:5Z3L|rcsb pdb:5Z3O|rcsb pdb:5Z3U|rcsb pdb:5Z3V|rcsb pdb:6ESF|rcsb pdb:6ESG|rcsb pdb:6ESH|rcsb pdb:6ESI|rcsb pdb:6FQ5|rcsb pdb:6FQ6|rcsb pdb:1ZBB|rcsb pdb:1ZLA|rcsb pdb:2F8N|rcsb pdb:2FJ7|rcsb pdb:2HUE|rcsb pdb:2IO5|rcsb pdb:2NZD|rcsb pdb:3B6F|rcsb pdb:3B6G|rcsb pdb:3C1B|rcsb pdb:3C1C|rcsb pdb:3KUY|rcsb pdb:3KWQ|rcsb pdb:3KXB|rcsb pdb:3LEL|rcsb pdb:3LJA|rcsb pdb:3LZ0|rcsb pdb:3LZ1|rcsb pdb:3MGP|rcsb pdb:3MGQ|rcsb pdb:3MGR|rcsb pdb:3MGS|rcsb pdb:3MNN|rcsb pdb:3MVD|rcsb pdb:3O62|rcsb pdb:3REH|rcsb pdb:3REI|rcsb pdb:3REJ|rcsb pdb:3REK|rcsb pdb:3REL|rcsb pdb:3TU4|rcsb pdb:3UT9|rcsb pdb:3UTA|rcsb pdb:3UTB|rcsb pdb:4EO5|rcsb pdb:4J8U|rcsb pdb:4J8V|rcsb pdb:4J8W|rcsb pdb:4J8X|rcsb pdb:4KGC|rcsb pdb:4LD9|rcsb pdb:4R8P|rcsb pdb:4WU8|rcsb pdb:4WU9|rcsb pdb:4XUJ|rcsb pdb:4XZQ|rcsb pdb:4YS3|rcsb pdb:4Z66|rcsb pdb:4ZBJ|rcsb pdb:4ZUX|rcsb pdb:5BS7|rcsb pdb:6FQ8|rcsb pdb:6PWW|rcsb pdb:6FTX|rcsb pdb:6G0L|rcsb pdb:6GYT|rcsb pdb:6I84|rcsb pdb:6IRO|rcsb pdb:6IY2|rcsb pdb:6IY3|rcsb pdb:6J99|rcsb pdb:6JM9|rcsb pdb:6JMA|rcsb pdb:6JYL|rcsb pdb:6K1P|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LTJ|rcsb pdb:6NE3|rcsb pdb:6NJ9|rcsb pdb:6NN6|rcsb pdb:6NOG|rcsb pdb:6NQA|rcsb pdb:6NZO|rcsb pdb:6O22|rcsb pdb:6O96|rcsb pdb:6OM3|rcsb pdb:6PA7|rcsb pdb:6PWV|refseq:NP_001087926.1|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WKR|rcsb pdb:6WZ5|rcsb pdb:6WZ9|rcsb pdb:6X0N|rcsb pdb:6ZHX|rcsb pdb:6ZHY|rcsb pdb:7AT8|rcsb pdb:7CRO|rcsb pdb:7CRP|rcsb pdb:7CRQ|rcsb pdb:7CRR|rcsb pdb:7E8I|rcsb pdb:7K6P|rcsb pdb:7K6Q|rcsb pdb:7KTQ|rcsb pdb:6PWX|rcsb pdb:6PX1|rcsb pdb:6PX3|rcsb pdb:6R1T|rcsb pdb:6R1U|rcsb pdb:6R25|rcsb pdb:6RYR|rcsb pdb:6RYU|rcsb pdb:6S01|rcsb pdb:6T9L|rcsb pdb:6TDA|rcsb pdb:6TEM|rcsb pdb:6UGM|rcsb pdb:6UH5|rcsb pdb:6UXW|rcsb pdb:6VEN|rcsb pdb:6VYP|rcsb pdb:6VZ4|rcsb pdb:6W5I|dip:DIP-37429N|refseq:XP_018095104.1|refseq:XP_018095605.1|refseq:XP_018095606.1|refseq:XP_018096302.1|refseq:XP_018097458.1|refseq:XP_018098137.1|refseq:XP_018118237.1|refseq:XP_018120359.1|refseq:XP_018120360.1	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Fig. 1b|comment:Xenopus H3 was also present but could not be linked to a single gene product|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/03/30	2021/09/02	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA8355	rigid:G97xRVjN2UiCyWTK0kcLVx/wwWg	false	binding-associated region:1-172	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q9Y294	uniprotkb:Q8TEX9-1	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-27051042|ensembl:ENSP00000346453|ensembl:ENSP00000494795	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:q8tex9-1(display_long)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)	psi-mi:"MI:0031"(protein cross-linking with a bifunctional reagent)	Yoon et al. (2018)	imex:IM-29189|pubmed:29408485	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-27051058|imex:IM-29189-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F	ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|intact:EBI-395967(isoform-parent)	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Fig. 1b|comment:Xenopus H3 was also present but could not be linked to a single gene product|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/03/30	2021/09/02	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rigid:G97xRVjN2UiCyWTK0kcLVx/wwWg	false	binding-associated region:1-172	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q8TEX9-1	intact:EBI-27051089	intact:EBI-27051042|ensembl:ENSP00000346453|ensembl:ENSP00000494795	-	psi-mi:q8tex9-1(display_long)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)	psi-mi:h3 histone tail(display_short)|psi-mi:EBI-27051089(display_long)	psi-mi:"MI:0107"(surface plasmon resonance)	Yoon et al. (2018)	imex:IM-29189|pubmed:29408485	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-27051101|imex:IM-29189-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|intact:EBI-395967(isoform-parent)	-	-	-	-	figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/03/30	2021/09/02	rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606	rogid:cLhrE1NgzPvga5vIVD8ObXYntg08355	rigid:mOEmbHY9Y5kSohMwsxx9P+usQpM	false	binding-associated region:668-1081	necessary binding region:12-18	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-27051089	uniprotkb:A0A6J3QXS3	-	intact:EBI-27077105	psi-mi:h3 histone tail(display_short)|psi-mi:EBI-27051089(display_long)	psi-mi:a0a6j3qxs3_turtr(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Yoon et al. (2018)	imex:IM-29189|pubmed:29408485	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9739(Atlantic bottle-nosed dolphin)|taxid:9739(Tursiops truncatus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-27051121|imex:IM-29189-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|refseq:XP_033707147.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000357(HEAT)|interpro:IPR021133|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR040122|interpro:IPR034085	-	-	-	figure legend:Fig. 4h-j|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/03/30	2021/09/02	rogid:cLhrE1NgzPvga5vIVD8ObXYntg08355	rogid:3+TVxMXWP2UY+5sEMzDXpGXsvYc9739	rigid:GxZrKNz9Cv2Ph/z4ezwQfvIedss	false	mutation decreasing interaction strength:14-14|mutation decreasing interaction strength:14-14|mutation with no effect:13-13	binding-associated region:665-1078	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)