#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14B62	uniprotkb:P62717	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8327568|uniprotkb:P11249|intact:MINT-1841289|uniprotkb:Q3TSN0|ensembl:ENSMUSP00000058368	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl18a_mouse(display_long)|uniprotkb:Rpl18a(gene name)|psi-mi:Rpl18a(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_084027.1|ensembl:ENSMUSG00000045128(gene)|ensembl:ENSMUST00000054220(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:P62717|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:HMbe4GVCuVZs0/90BMnEgpOqeiA10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P61358	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8401481|intact:MINT-1863099|ensembl:ENSMUSP00000090305|ensembl:ENSMUSP00000102870	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl27_mouse(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_035419.1|refseq:XP_017170385.1|ensembl:ENSMUSG00000063316(gene)|ensembl:ENSMUST00000077856(transcript)|ensembl:ENSMUST00000107249(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61358|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O35343	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8372758|intact:MINT-4098648|ensembl:ENSMUSP00000141227	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:ima3_mouse(display_long)|uniprotkb:Kpna4(gene name)|psi-mi:Kpna4(display_short)|uniprotkb:Qip1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032493.1|dip:DIP-62053N|ensembl:ENSMUSG00000027782(gene)|ensembl:ENSMUST00000194558(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O35343	-	-	comment:mint|function:"Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus"	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:FNkP/rMLdR4xUoOYLuHsT710FeA10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQH3	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P14148	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6P1F6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-997427|ensembl:ENSMUSP00000086640	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:2aba_mouse(display_long)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:Ppp2r2a(gene name)|psi-mi:Ppp2r2a(display_short)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001192117.1|refseq:NP_082308.1|ensembl:ENSMUSG00000022052(gene)|ensembl:ENSMUST00000089230(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q6P1F6|reactome:R-MMU-2995383|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:evS6klM2alZXtMthVsshKkrNgiA10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q61733	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-25413581|ensembl:ENSMUSP00000033934|uniprotkb:Q3TSP5|uniprotkb:Q8VEH4|uniprotkb:Q9D045	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rt31_mouse(display_long)|uniprotkb:Mrps31(gene name)|psi-mi:Mrps31(display_short)|uniprotkb:Imogn38(gene name synonym)|uniprotkb:Imogen 38(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	reactome:R-MMU-5389840|ensembl:ENSMUSG00000031533(gene)|ensembl:ENSMUST00000033934(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|reactome:R-MMU-5419276|refseq:NP_065585.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:hjswAOZchuDlhu6+pvQBFKdQDOs10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62918	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62900	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2527089|uniprotkb:P12947|ensembl:ENSMUSP00000083722|ensembl:ENSMUSP00000136354|ensembl:ENSMUSP00000137631	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl31_mouse(display_long)|uniprotkb:Rpl31(gene name)|psi-mi:Rpl31(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000073702(gene)|ensembl:ENSMUST00000086535(transcript)|ensembl:ENSMUST00000178079(transcript)|ensembl:ENSMUST00000179954(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62900|rcsb pdb:6SWA|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-156827|refseq:NP_444487.1|refseq:NP_001239147.1|refseq:NP_001239148.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:77LFR7/2somk6blVogZf1XFdJLk10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62855	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P47962	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-773940|uniprotkb:Q9CR19|ensembl:ENSMUSP00000080854	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl5_mouse(display_long)|uniprotkb:Rpl5(gene name)|psi-mi:Rpl5(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058676.1|ensembl:ENSMUSG00000058558(gene)|ensembl:ENSMUST00000082223(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905017"(positive regulation of isoleucine-tRNA ligase activity)|go:"GO:1905020"(positive regulation of methionine-tRNA ligase activity)|go:"GO:1905023"(positive regulation of threonine-tRNA ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P47962|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:29DmVSczDJV/5gL/nPYYBBEdo9o10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P28798	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2365205|ensembl:ENSMUSP00000159379	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:grn_mouse(display_long)|uniprotkb:Grn(gene name)|psi-mi:Grn(display_short)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin/granulin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105940|imex:IM-29291-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032201.2|ensembl:ENSMUSG00000034708(gene)|ensembl:ENSMUST00000239431(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007566"(embryo implantation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060179"(male mating behavior)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098793"(presynapse)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905671"(regulation of lysosome organization)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28798|reactome:R-MMU-6798695	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:2nKMRNqLyZN/IXAvz1zMzDCpDmg10090	rigid:WxkWrTfLxyuQRagIC72l28uUq+o	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6RHR9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7440897|uniprotkb:O54894|uniprotkb:O54893|uniprotkb:O54895|intact:MINT-150460|ensembl:ENSMUSP00000086730	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi1_mouse(display_long)|uniprotkb:Magi1(gene name)|psi-mi:Magi1(display_short)|uniprotkb:Baiap1(gene name synonym)|uniprotkb:Bap1(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_034497.1|refseq:NP_001025021.1|ensembl:ENSMUSG00000045095(gene)|ensembl:ENSMUST00000089317(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071944"(cell periphery)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030033|interpro:IPR036020|interpro:IPR036034|rcsb pdb:2I04|rcsb pdb:5ZYS	-	-	comment:mint|function:May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:mk1dW19+wMHjMLcuieBAQSHEs3U10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q91XM9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-400138|uniprotkb:Q8BXK7|uniprotkb:Q8BYG5|ensembl:ENSMUSP00000102814|uniprotkb:F8VQM7	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg2_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107196(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:Q91XM9|rcsb pdb:2WL7|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6794361|refseq:NP_001229976.1|refseq:NP_035937.2|dip:DIP-31569N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:37/IFbjDNxh87dnN2gglIgDGyIU10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q811D0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q62108	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q61234	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3UHD6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910393|ensembl:ENSMUSP00000102904|uniprotkb:Q7TQL6|uniprotkb:Q80TZ1|uniprotkb:Q9CYB5	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snx27_mouse(display_long)|uniprotkb:Snx27(gene name)|psi-mi:Snx27(display_short)|uniprotkb:Kiaa0488(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0030904"(retromer complex)|ensembl:ENSMUSG00000028136(gene)|ensembl:ENSMUST00000107283(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0071203"(WASH complex)|go:"GO:0005768"(endosome)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0005769"(early endosome)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|go:"GO:0005829"(cytosol)|interpro:IPR036034|go:"GO:0005886"(plasma membrane)|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q3UHD6|refseq:NP_001075953.1|refseq:NP_083997.1|dip:DIP-60337N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+pFe87lSKQPJuMDWsiMU4iXhGOw10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P70175	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-396969|ensembl:ENSMUSP00000085299	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg3_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058027.1|refseq:NP_001171249.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000087984(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:P70175|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-6794361|reactome:R-MMU-8849932|dip:DIP-31585N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9dR9P876v8QcvPinxtaWzDgpHwE10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O70589	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771402|uniprotkb:A2ADP8|uniprotkb:A2ADP9|uniprotkb:A2ADQ4|uniprotkb:O70588|uniprotkb:Q3UW92	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:cskp_mouse(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short)|uniprotkb:Lin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105968|imex:IM-29291-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001271432.1|refseq:NP_001271433.1|refseq:NP_001271434.1|refseq:NP_033936.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O70589|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:1Y74|rcsb pdb:6Y9O|reactome:R-MMU-212676|reactome:R-MMU-6794361|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3co6JdI4q/n5C8zGb5JYFL2t7pc10090	rigid:h7ze8TtSkWQNDVb/RvGYEJkhvkg	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8C0E2	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8314940|ensembl:ENSMUSP00000034470|uniprotkb:Q8K2V3|uniprotkb:Q3TN45|intact:MINT-3253852	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vp26b_mouse(display_long)|uniprotkb:Vps26b(gene name)|psi-mi:Vps26b(display_short)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000031988(gene)|ensembl:ENSMUST00000034470(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:Q8C0E2|rcsb pdb:2R51|rcsb pdb:3LH8|rcsb pdb:3LH9|rcsb pdb:3LHA|refseq:NP_821170.1	-	-	comment:mint|function:"Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network"	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:0ldtjq7g6fEiaFTAusA8J+Xy4Qg10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62911	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8328122|intact:MINT-1854367|uniprotkb:Q3UFJ7|uniprotkb:P02433|ensembl:ENSMUSP00000080523|ensembl:ENSMUSP00000145350	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl32_mouse(display_long)|uniprotkb:Rpl32(gene name)|psi-mi:Rpl32(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_742083.1|ensembl:ENSMUSG00000057841(gene)|ensembl:ENSMUST00000081840(transcript)|ensembl:ENSMUST00000203816(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P43275	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8338024|uniprotkb:Q5SZ98|intact:MINT-1868385|ensembl:ENSMUSP00000062030	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h11_mouse(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1 VAR.3(gene name synonym)|uniprotkb:H1a(gene name synonym)|uniprotkb:H1f1(gene name synonym)|uniprotkb:Hist1h1a(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_085112.1|ensembl:ENSMUSG00000049539(gene)|ensembl:ENSMUST00000055770(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0031982"(vesicle)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43275|reactome:R-MMU-140342|reactome:R-MMU-2559584	-	-	function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures|comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:rVet/mPRsJO0PzM0pRx+ukzOLVw10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQH3	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P47962	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-773940|uniprotkb:Q9CR19|ensembl:ENSMUSP00000080854	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl5_mouse(display_long)|uniprotkb:Rpl5(gene name)|psi-mi:Rpl5(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058676.1|ensembl:ENSMUSG00000058558(gene)|ensembl:ENSMUST00000082223(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905017"(positive regulation of isoleucine-tRNA ligase activity)|go:"GO:1905020"(positive regulation of methionine-tRNA ligase activity)|go:"GO:1905023"(positive regulation of threonine-tRNA ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P47962|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:29DmVSczDJV/5gL/nPYYBBEdo9o10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6ZWV7	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2554199|ensembl:ENSMUSP00000079672|ensembl:ENSMUSP00000099843	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl35_mouse(display_long)|uniprotkb:Rpl35(gene name)|psi-mi:Rpl35(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_079868.1|ensembl:ENSMUSG00000062997(gene)|ensembl:ENSMUSG00000078193(gene)|ensembl:ENSMUST00000080861(transcript)|ensembl:ENSMUST00000102782(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0071493"(cellular response to UV-B)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:UbB74zfkV+b0wqxTLx8egN1J8N810090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3TEA8	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6665967|ensembl:ENSMUSP00000030541|ensembl:ENSMUSP00000132614|uniprotkb:A2AM64|uniprotkb:A2AM68|uniprotkb:Q3TM38|uniprotkb:Q3TU07|uniprotkb:Q61688|uniprotkb:Q8BT17|uniprotkb:Q8C6H2|uniprotkb:Q8C911|uniprotkb:Q8VE06|uniprotkb:Q99KR0|uniprotkb:Q9DBI1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:hp1b3_mouse(display_long)|uniprotkb:Hp1bp3(gene name)|psi-mi:Hp1bp3(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001272407.1|refseq:NP_001272408.1|refseq:NP_001272409.1|refseq:NP_001272410.1|ensembl:ENSMUSG00000028759(gene)|ensembl:ENSMUST00000030541(transcript)|ensembl:ENSMUST00000165861(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|mint:Q3TEA8|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|refseq:XP_006538631.1|refseq:XP_006538633.1|refseq:NP_001116368.1|refseq:NP_001116369.1|refseq:NP_034600.2	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:slrlB/B0DUfN8npc59xviu74mxs10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P15864	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-913436|ensembl:ENSMUSP00000045816	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h12_mouse(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1 VAR.1(gene name synonym)|uniprotkb:H1c(gene name synonym)|uniprotkb:H1f2(gene name synonym)|uniprotkb:Hist1h1c(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_056601.1|ensembl:ENSMUSG00000036181(gene)|ensembl:ENSMUST00000040914(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P15864|reactome:R-MMU-140342|reactome:R-MMU-2559584|dip:DIP-35245N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:xZTLhoQ8/vdiyHIxpxFNUWquFf810090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P10922	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-529651|uniprotkb:Q3UKC0|ensembl:ENSMUSP00000137309	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h10_mouse(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1f0(gene name synonym)|uniprotkb:H1fv(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym)|uniprotkb:MyD196(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032223.2|ensembl:ENSMUSG00000096210(gene)|ensembl:ENSMUST00000180086(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10922|reactome:R-MMU-140342|reactome:R-MMU-2559584	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:O/PNarQrFWH/SALoDATRxhetTEA10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P28798	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2365205|ensembl:ENSMUSP00000159379	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:grn_mouse(display_long)|uniprotkb:Grn(gene name)|psi-mi:Grn(display_short)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin/granulin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032201.2|ensembl:ENSMUSG00000034708(gene)|ensembl:ENSMUST00000239431(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007566"(embryo implantation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060179"(male mating behavior)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098793"(presynapse)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905671"(regulation of lysosome organization)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28798|reactome:R-MMU-6798695	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:2nKMRNqLyZN/IXAvz1zMzDCpDmg10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9Z0Y1	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2552776|ensembl:ENSMUSP00000030158|uniprotkb:Q9CR43|uniprotkb:Q9D039	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dctn3_mouse(display_long)|uniprotkb:Dynactin light chain p24(gene name synonym)|uniprotkb:Dctn3(gene name)|psi-mi:Dctn3(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001153037.1|refseq:NP_058586.3|ensembl:ENSMUSG00000028447(gene)|ensembl:ENSMUST00000030158(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR009991(Dynactin subunit p22)|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:BjcdhIIVk+9CQjJ1I4VfmjHRkAE10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8CH18	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-645246|uniprotkb:Q6AXC9|uniprotkb:Q6PAR2|uniprotkb:Q80XE4|uniprotkb:Q8BJY0|uniprotkb:Q8BVN2|uniprotkb:Q8CGG1|uniprotkb:Q9CSR5|uniprotkb:Q05BR1|uniprotkb:Q05DK6|ensembl:ENSMUSP00000020268|ensembl:ENSMUSP00000151895	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:ccar1_mouse(display_long)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Ccar1(gene name)|psi-mi:Ccar1(display_short)|uniprotkb:Carp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105988|imex:IM-29291-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_080477.1|refseq:XP_006514057.1|refseq:XP_006514058.1|refseq:XP_006514059.1|refseq:XP_006514060.1|refseq:XP_011241839.1|ensembl:ENSMUSG00000020074(gene)|ensembl:ENSMUST00000020268(transcript)|ensembl:ENSMUST00000219527(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8CH18|reactome:R-MMU-72163	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:fipMhp0uguP4AXVte036ScUyq5g10090	rigid:/EnD3pRFyXvDHo8danzwH9UskKY	false	glutathione s tranferase tag:n-n|sufficient binding region:847-884|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQJ9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7455245|uniprotkb:Q8C0P8|intact:MINT-1894696|uniprotkb:B0V3N7|intact:UNK-5947369|uniprotkb:Q69ZE1|uniprotkb:B0V3N8	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi3_mouse(display_long)|uniprotkb:Magi3(gene name)|psi-mi:Magi3(display_short)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym)|uniprotkb:Kiaa1634(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	interpro:IPR030035|mint:Q9EQJ9|interpro:IPR036034|interpro:IPR036020|interpro:IPR020590|interpro:IPR027417|refseq:NP_598614.1|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|go:"GO:0005109"(frizzled binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)	-	-	comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:LbFYUmxao9TmprW22YUA3GS9nCs10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6RHR9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7440897|uniprotkb:O54894|uniprotkb:O54893|uniprotkb:O54895|intact:MINT-150460|ensembl:ENSMUSP00000086730	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi1_mouse(display_long)|uniprotkb:Magi1(gene name)|psi-mi:Magi1(display_short)|uniprotkb:Baiap1(gene name synonym)|uniprotkb:Bap1(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_034497.1|refseq:NP_001025021.1|ensembl:ENSMUSG00000045095(gene)|ensembl:ENSMUST00000089317(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071944"(cell periphery)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030033|interpro:IPR036020|interpro:IPR036034|rcsb pdb:2I04|rcsb pdb:5ZYS	-	-	comment:mint|function:May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:mk1dW19+wMHjMLcuieBAQSHEs3U10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3UHD6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910393|ensembl:ENSMUSP00000102904|uniprotkb:Q7TQL6|uniprotkb:Q80TZ1|uniprotkb:Q9CYB5	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snx27_mouse(display_long)|uniprotkb:Snx27(gene name)|psi-mi:Snx27(display_short)|uniprotkb:Kiaa0488(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0030904"(retromer complex)|ensembl:ENSMUSG00000028136(gene)|ensembl:ENSMUST00000107283(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0071203"(WASH complex)|go:"GO:0005768"(endosome)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0005769"(early endosome)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|go:"GO:0005829"(cytosol)|interpro:IPR036034|go:"GO:0005886"(plasma membrane)|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q3UHD6|refseq:NP_001075953.1|refseq:NP_083997.1|dip:DIP-60337N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+pFe87lSKQPJuMDWsiMU4iXhGOw10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9JLB0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771456|uniprotkb:Q9JLB1|uniprotkb:Q9WV37|ensembl:ENSMUSP00000038772|ensembl:ENSMUSP00000125880	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:pals2_mouse(display_long)|uniprotkb:Pals2(gene name)|psi-mi:Pals2(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Dlgh4 protein(gene name synonym)|uniprotkb:MAGUK p55 subfamily member 6(gene name synonym)|uniprotkb:Mpp6(gene name synonym)|uniprotkb:P55T protein(gene name synonym)|uniprotkb:Protein associated with Lin-7 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001158205.1|refseq:NP_001158206.1|refseq:NP_064323.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035603|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q9JLB0|ensembl:ENSMUSG00000038388(gene)|ensembl:ENSMUST00000036225(transcript)|ensembl:ENSMUST00000166318(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:gMNWZ/pRWUn+VfBE5m6SZc9IvqA10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9WV34	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-444614|ensembl:ENSMUSP00000017458|uniprotkb:Q3T9W1|uniprotkb:Q3TT52|uniprotkb:Q3URK8|uniprotkb:B1AQF8	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:mpp2_mouse(display_long)|uniprotkb:Protein MPP2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Mpp2(gene name)|psi-mi:Mpp2(display_short)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_057904.1|ensembl:ENSMUSG00000017314(gene)|ensembl:ENSMUST00000017458(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035602|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q9WV34|go:"GO:0098919"(structural constituent of postsynaptic density)|refseq:XP_006533746.1|refseq:XP_006533747.1|refseq:XP_006533748.1	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:KythGhvpyj7gkND18iMe73LgdtM10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q91XM9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-400138|uniprotkb:Q8BXK7|uniprotkb:Q8BYG5|ensembl:ENSMUSP00000102814|uniprotkb:F8VQM7	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg2_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107196(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:Q91XM9|rcsb pdb:2WL7|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6794361|refseq:NP_001229976.1|refseq:NP_035937.2|dip:DIP-31569N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:37/IFbjDNxh87dnN2gglIgDGyIU10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8JZS0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-770029|ensembl:ENSMUSP00000020057	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:lin7a_mouse(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001034443.1|ensembl:ENSMUSG00000019906(gene)|ensembl:ENSMUST00000020057(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q8JZS0|reactome:R-MMU-212676	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:WE2wsFc8aJ7M4lPbTJe4T4uquig10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P14602	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8BH60	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q62108	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P70175	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-396969|ensembl:ENSMUSP00000085299	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg3_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058027.1|refseq:NP_001171249.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000087984(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:P70175|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-6794361|reactome:R-MMU-8849932|dip:DIP-31585N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9dR9P876v8QcvPinxtaWzDgpHwE10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q811D0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O70589	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771402|uniprotkb:A2ADP8|uniprotkb:A2ADP9|uniprotkb:A2ADQ4|uniprotkb:O70588|uniprotkb:Q3UW92	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:cskp_mouse(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short)|uniprotkb:Lin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27106010|imex:IM-29291-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001271432.1|refseq:NP_001271433.1|refseq:NP_001271434.1|refseq:NP_033936.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O70589|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:1Y74|rcsb pdb:6Y9O|reactome:R-MMU-212676|reactome:R-MMU-6794361|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3co6JdI4q/n5C8zGb5JYFL2t7pc10090	rigid:ixF5Dnvi5GVvNjbCg+zxo7y4fhQ	false	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6RHR9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7440897|uniprotkb:O54894|uniprotkb:O54893|uniprotkb:O54895|intact:MINT-150460|ensembl:ENSMUSP00000086730	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi1_mouse(display_long)|uniprotkb:Magi1(gene name)|psi-mi:Magi1(display_short)|uniprotkb:Baiap1(gene name synonym)|uniprotkb:Bap1(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_034497.1|refseq:NP_001025021.1|ensembl:ENSMUSG00000045095(gene)|ensembl:ENSMUST00000089317(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071944"(cell periphery)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030033|interpro:IPR036020|interpro:IPR036034|rcsb pdb:2I04|rcsb pdb:5ZYS	-	-	comment:mint|function:May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:mk1dW19+wMHjMLcuieBAQSHEs3U10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62717	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8327568|uniprotkb:P11249|intact:MINT-1841289|uniprotkb:Q3TSN0|ensembl:ENSMUSP00000058368	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl18a_mouse(display_long)|uniprotkb:Rpl18a(gene name)|psi-mi:Rpl18a(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_084027.1|ensembl:ENSMUSG00000045128(gene)|ensembl:ENSMUST00000054220(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:P62717|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:HMbe4GVCuVZs0/90BMnEgpOqeiA10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P61358	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8401481|intact:MINT-1863099|ensembl:ENSMUSP00000090305|ensembl:ENSMUSP00000102870	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl27_mouse(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_035419.1|refseq:XP_017170385.1|ensembl:ENSMUSG00000063316(gene)|ensembl:ENSMUST00000077856(transcript)|ensembl:ENSMUST00000107249(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61358|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O35343	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8372758|intact:MINT-4098648|ensembl:ENSMUSP00000141227	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:ima3_mouse(display_long)|uniprotkb:Kpna4(gene name)|psi-mi:Kpna4(display_short)|uniprotkb:Qip1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032493.1|dip:DIP-62053N|ensembl:ENSMUSG00000027782(gene)|ensembl:ENSMUST00000194558(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O35343	-	-	comment:mint|function:"Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus"	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:FNkP/rMLdR4xUoOYLuHsT710FeA10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q91XM9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-400138|uniprotkb:Q8BXK7|uniprotkb:Q8BYG5|ensembl:ENSMUSP00000102814|uniprotkb:F8VQM7	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg2_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107196(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:Q91XM9|rcsb pdb:2WL7|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6794361|refseq:NP_001229976.1|refseq:NP_035937.2|dip:DIP-31569N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:37/IFbjDNxh87dnN2gglIgDGyIU10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q811D0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q62108	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q61234	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3UHD6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910393|ensembl:ENSMUSP00000102904|uniprotkb:Q7TQL6|uniprotkb:Q80TZ1|uniprotkb:Q9CYB5	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snx27_mouse(display_long)|uniprotkb:Snx27(gene name)|psi-mi:Snx27(display_short)|uniprotkb:Kiaa0488(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0030904"(retromer complex)|ensembl:ENSMUSG00000028136(gene)|ensembl:ENSMUST00000107283(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0071203"(WASH complex)|go:"GO:0005768"(endosome)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0005769"(early endosome)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|go:"GO:0005829"(cytosol)|interpro:IPR036034|go:"GO:0005886"(plasma membrane)|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q3UHD6|refseq:NP_001075953.1|refseq:NP_083997.1|dip:DIP-60337N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+pFe87lSKQPJuMDWsiMU4iXhGOw10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P70175	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-396969|ensembl:ENSMUSP00000085299	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg3_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058027.1|refseq:NP_001171249.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000087984(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:P70175|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-6794361|reactome:R-MMU-8849932|dip:DIP-31585N	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9dR9P876v8QcvPinxtaWzDgpHwE10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O70589	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771402|uniprotkb:A2ADP8|uniprotkb:A2ADP9|uniprotkb:A2ADQ4|uniprotkb:O70588|uniprotkb:Q3UW92	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:cskp_mouse(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short)|uniprotkb:Lin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001271432.1|refseq:NP_001271433.1|refseq:NP_001271434.1|refseq:NP_033936.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O70589|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:1Y74|rcsb pdb:6Y9O|reactome:R-MMU-212676|reactome:R-MMU-6794361|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3co6JdI4q/n5C8zGb5JYFL2t7pc10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQH3	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P14148	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6P1F6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-997427|ensembl:ENSMUSP00000086640	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:2aba_mouse(display_long)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:Ppp2r2a(gene name)|psi-mi:Ppp2r2a(display_short)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001192117.1|refseq:NP_082308.1|ensembl:ENSMUSG00000022052(gene)|ensembl:ENSMUST00000089230(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:Q6P1F6|reactome:R-MMU-2995383|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:evS6klM2alZXtMthVsshKkrNgiA10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q61733	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-25413581|ensembl:ENSMUSP00000033934|uniprotkb:Q3TSP5|uniprotkb:Q8VEH4|uniprotkb:Q9D045	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rt31_mouse(display_long)|uniprotkb:Mrps31(gene name)|psi-mi:Mrps31(display_short)|uniprotkb:Imogn38(gene name synonym)|uniprotkb:Imogen 38(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	reactome:R-MMU-5389840|ensembl:ENSMUSG00000031533(gene)|ensembl:ENSMUST00000033934(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|reactome:R-MMU-5419276|refseq:NP_065585.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:hjswAOZchuDlhu6+pvQBFKdQDOs10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62918	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62900	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2527089|uniprotkb:P12947|ensembl:ENSMUSP00000083722|ensembl:ENSMUSP00000136354|ensembl:ENSMUSP00000137631	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl31_mouse(display_long)|uniprotkb:Rpl31(gene name)|psi-mi:Rpl31(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000073702(gene)|ensembl:ENSMUST00000086535(transcript)|ensembl:ENSMUST00000178079(transcript)|ensembl:ENSMUST00000179954(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62900|rcsb pdb:6SWA|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-156827|refseq:NP_444487.1|refseq:NP_001239147.1|refseq:NP_001239148.1	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:77LFR7/2somk6blVogZf1XFdJLk10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62855	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P47962	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-773940|uniprotkb:Q9CR19|ensembl:ENSMUSP00000080854	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl5_mouse(display_long)|uniprotkb:Rpl5(gene name)|psi-mi:Rpl5(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058676.1|ensembl:ENSMUSG00000058558(gene)|ensembl:ENSMUST00000082223(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905017"(positive regulation of isoleucine-tRNA ligase activity)|go:"GO:1905020"(positive regulation of methionine-tRNA ligase activity)|go:"GO:1905023"(positive regulation of threonine-tRNA ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P47962|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:29DmVSczDJV/5gL/nPYYBBEdo9o10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P28798	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2365205|ensembl:ENSMUSP00000159379	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:grn_mouse(display_long)|uniprotkb:Grn(gene name)|psi-mi:Grn(display_short)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin/granulin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110810|imex:IM-29291-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032201.2|ensembl:ENSMUSG00000034708(gene)|ensembl:ENSMUST00000239431(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007566"(embryo implantation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060179"(male mating behavior)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098793"(presynapse)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905671"(regulation of lysosome organization)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28798|reactome:R-MMU-6798695	-	-	-	figure legend:F5C|comment:this interaction occurs in membrane fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:2nKMRNqLyZN/IXAvz1zMzDCpDmg10090	rigid:QD7Dcpe1RMYOR3+oHA5uDVDG700	false	binding-associated region:847-888|his tag:n-n|mutation:870-870|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQJ9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7455245|uniprotkb:Q8C0P8|intact:MINT-1894696|uniprotkb:B0V3N7|intact:UNK-5947369|uniprotkb:Q69ZE1|uniprotkb:B0V3N8	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi3_mouse(display_long)|uniprotkb:Magi3(gene name)|psi-mi:Magi3(display_short)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym)|uniprotkb:Kiaa1634(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	interpro:IPR030035|mint:Q9EQJ9|interpro:IPR036034|interpro:IPR036020|interpro:IPR020590|interpro:IPR027417|refseq:NP_598614.1|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|go:"GO:0005109"(frizzled binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)	-	-	comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:LbFYUmxao9TmprW22YUA3GS9nCs10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6RHR9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-7440897|uniprotkb:O54894|uniprotkb:O54893|uniprotkb:O54895|intact:MINT-150460|ensembl:ENSMUSP00000086730	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:magi1_mouse(display_long)|uniprotkb:Magi1(gene name)|psi-mi:Magi1(display_short)|uniprotkb:Baiap1(gene name synonym)|uniprotkb:Bap1(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_034497.1|refseq:NP_001025021.1|ensembl:ENSMUSG00000045095(gene)|ensembl:ENSMUST00000089317(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071944"(cell periphery)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030033|interpro:IPR036020|interpro:IPR036034|rcsb pdb:2I04|rcsb pdb:5ZYS	-	-	comment:mint|function:May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:mk1dW19+wMHjMLcuieBAQSHEs3U10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8C0E2	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8314940|ensembl:ENSMUSP00000034470|uniprotkb:Q8K2V3|uniprotkb:Q3TN45|intact:MINT-3253852	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vp26b_mouse(display_long)|uniprotkb:Vps26b(gene name)|psi-mi:Vps26b(display_short)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000031988(gene)|ensembl:ENSMUST00000034470(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030904"(retromer complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:Q8C0E2|rcsb pdb:2R51|rcsb pdb:3LH8|rcsb pdb:3LH9|rcsb pdb:3LHA|refseq:NP_821170.1	-	-	comment:mint|function:"Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network"	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:0ldtjq7g6fEiaFTAusA8J+Xy4Qg10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P62911	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8328122|intact:MINT-1854367|uniprotkb:Q3UFJ7|uniprotkb:P02433|ensembl:ENSMUSP00000080523|ensembl:ENSMUSP00000145350	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl32_mouse(display_long)|uniprotkb:Rpl32(gene name)|psi-mi:Rpl32(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_742083.1|ensembl:ENSMUSG00000057841(gene)|ensembl:ENSMUST00000081840(transcript)|ensembl:ENSMUST00000203816(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P43275	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-8338024|uniprotkb:Q5SZ98|intact:MINT-1868385|ensembl:ENSMUSP00000062030	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h11_mouse(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1 VAR.3(gene name synonym)|uniprotkb:H1a(gene name synonym)|uniprotkb:H1f1(gene name synonym)|uniprotkb:Hist1h1a(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_085112.1|ensembl:ENSMUSG00000049539(gene)|ensembl:ENSMUST00000055770(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0031982"(vesicle)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43275|reactome:R-MMU-140342|reactome:R-MMU-2559584	-	-	function:Histones H1 are necessary for the condensation of nucleosome chains into higher order structures|comment:mint	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:rVet/mPRsJO0PzM0pRx+ukzOLVw10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3UHD6	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6910393|ensembl:ENSMUSP00000102904|uniprotkb:Q7TQL6|uniprotkb:Q80TZ1|uniprotkb:Q9CYB5	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:snx27_mouse(display_long)|uniprotkb:Snx27(gene name)|psi-mi:Snx27(display_short)|uniprotkb:Kiaa0488(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0030904"(retromer complex)|ensembl:ENSMUSG00000028136(gene)|ensembl:ENSMUST00000107283(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0071203"(WASH complex)|go:"GO:0005768"(endosome)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0005769"(early endosome)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|go:"GO:0005829"(cytosol)|interpro:IPR036034|go:"GO:0005886"(plasma membrane)|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q3UHD6|refseq:NP_001075953.1|refseq:NP_083997.1|dip:DIP-60337N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:+pFe87lSKQPJuMDWsiMU4iXhGOw10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9JLB0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771456|uniprotkb:Q9JLB1|uniprotkb:Q9WV37|ensembl:ENSMUSP00000038772|ensembl:ENSMUSP00000125880	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:pals2_mouse(display_long)|uniprotkb:Pals2(gene name)|psi-mi:Pals2(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Dlgh4 protein(gene name synonym)|uniprotkb:MAGUK p55 subfamily member 6(gene name synonym)|uniprotkb:Mpp6(gene name synonym)|uniprotkb:P55T protein(gene name synonym)|uniprotkb:Protein associated with Lin-7 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001158205.1|refseq:NP_001158206.1|refseq:NP_064323.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035603|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q9JLB0|ensembl:ENSMUSG00000038388(gene)|ensembl:ENSMUST00000036225(transcript)|ensembl:ENSMUST00000166318(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001452(Src homology-3)	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:gMNWZ/pRWUn+VfBE5m6SZc9IvqA10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9WV34	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-444614|ensembl:ENSMUSP00000017458|uniprotkb:Q3T9W1|uniprotkb:Q3TT52|uniprotkb:Q3URK8|uniprotkb:B1AQF8	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:mpp2_mouse(display_long)|uniprotkb:Protein MPP2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Mpp2(gene name)|psi-mi:Mpp2(display_short)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_057904.1|ensembl:ENSMUSG00000017314(gene)|ensembl:ENSMUST00000017458(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035602|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q9WV34|go:"GO:0098919"(structural constituent of postsynaptic density)|refseq:XP_006533746.1|refseq:XP_006533747.1|refseq:XP_006533748.1	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:KythGhvpyj7gkND18iMe73LgdtM10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8JZS0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-770029|ensembl:ENSMUSP00000020057	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:lin7a_mouse(display_long)|uniprotkb:Mammalian lin-seven protein 1(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 1(gene name synonym)|uniprotkb:Lin7a(gene name)|psi-mi:Lin7a(display_short)|uniprotkb:Mals1(gene name synonym)|uniprotkb:Veli1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001034443.1|ensembl:ENSMUSG00000019906(gene)|ensembl:ENSMUST00000020057(transcript)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048839"(inner ear development)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q8JZS0|reactome:R-MMU-212676	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:WE2wsFc8aJ7M4lPbTJe4T4uquig10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P14602	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8BH60	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q62108	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P70175	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-396969|ensembl:ENSMUSP00000085299	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg3_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058027.1|refseq:NP_001171249.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000087984(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:P70175|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-6794361|reactome:R-MMU-8849932|dip:DIP-31585N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9dR9P876v8QcvPinxtaWzDgpHwE10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q91XM9	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-400138|uniprotkb:Q8BXK7|uniprotkb:Q8BYG5|ensembl:ENSMUSP00000102814|uniprotkb:F8VQM7	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg2_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107196(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:Q91XM9|rcsb pdb:2WL7|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6794361|refseq:NP_001229976.1|refseq:NP_035937.2|dip:DIP-31569N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:37/IFbjDNxh87dnN2gglIgDGyIU10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q811D0	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:O70589	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-771402|uniprotkb:A2ADP8|uniprotkb:A2ADP9|uniprotkb:A2ADQ4|uniprotkb:O70588|uniprotkb:Q3UW92	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:cskp_mouse(display_long)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Cask(gene name)|psi-mi:Cask(display_short)|uniprotkb:Lin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001271432.1|refseq:NP_001271433.1|refseq:NP_001271434.1|refseq:NP_033936.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O70589|go:"GO:0060170"(ciliary membrane)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098846"(podocyte foot)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|rcsb pdb:1Y74|rcsb pdb:6Y9O|reactome:R-MMU-212676|reactome:R-MMU-6794361|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0031982"(vesicle)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:3co6JdI4q/n5C8zGb5JYFL2t7pc10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQH3	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P47962	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-773940|uniprotkb:Q9CR19|ensembl:ENSMUSP00000080854	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl5_mouse(display_long)|uniprotkb:Rpl5(gene name)|psi-mi:Rpl5(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_058676.1|ensembl:ENSMUSG00000058558(gene)|ensembl:ENSMUST00000082223(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905017"(positive regulation of isoleucine-tRNA ligase activity)|go:"GO:1905020"(positive regulation of methionine-tRNA ligase activity)|go:"GO:1905023"(positive regulation of threonine-tRNA ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P47962|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:29DmVSczDJV/5gL/nPYYBBEdo9o10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q6ZWV7	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2554199|ensembl:ENSMUSP00000079672|ensembl:ENSMUSP00000099843	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:rl35_mouse(display_long)|uniprotkb:Rpl35(gene name)|psi-mi:Rpl35(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_079868.1|ensembl:ENSMUSG00000062997(gene)|ensembl:ENSMUSG00000078193(gene)|ensembl:ENSMUST00000080861(transcript)|ensembl:ENSMUST00000102782(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0071493"(cellular response to UV-B)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:UbB74zfkV+b0wqxTLx8egN1J8N810090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q3TEA8	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-6665967|ensembl:ENSMUSP00000030541|ensembl:ENSMUSP00000132614|uniprotkb:A2AM64|uniprotkb:A2AM68|uniprotkb:Q3TM38|uniprotkb:Q3TU07|uniprotkb:Q61688|uniprotkb:Q8BT17|uniprotkb:Q8C6H2|uniprotkb:Q8C911|uniprotkb:Q8VE06|uniprotkb:Q99KR0|uniprotkb:Q9DBI1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:hp1b3_mouse(display_long)|uniprotkb:Hp1bp3(gene name)|psi-mi:Hp1bp3(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001272407.1|refseq:NP_001272408.1|refseq:NP_001272409.1|refseq:NP_001272410.1|ensembl:ENSMUSG00000028759(gene)|ensembl:ENSMUST00000030541(transcript)|ensembl:ENSMUST00000165861(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|mint:Q3TEA8|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|refseq:XP_006538631.1|refseq:XP_006538633.1|refseq:NP_001116368.1|refseq:NP_001116369.1|refseq:NP_034600.2	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:slrlB/B0DUfN8npc59xviu74mxs10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P15864	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-913436|ensembl:ENSMUSP00000045816	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h12_mouse(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1 VAR.1(gene name synonym)|uniprotkb:H1c(gene name synonym)|uniprotkb:H1f2(gene name synonym)|uniprotkb:Hist1h1c(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_056601.1|ensembl:ENSMUSG00000036181(gene)|ensembl:ENSMUST00000040914(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P15864|reactome:R-MMU-140342|reactome:R-MMU-2559584|dip:DIP-35245N	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:xZTLhoQ8/vdiyHIxpxFNUWquFf810090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P10922	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-529651|uniprotkb:Q3UKC0|ensembl:ENSMUSP00000137309	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:h10_mouse(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1f0(gene name synonym)|uniprotkb:H1fv(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym)|uniprotkb:MyD196(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032223.2|ensembl:ENSMUSG00000096210(gene)|ensembl:ENSMUST00000180086(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10922|reactome:R-MMU-140342|reactome:R-MMU-2559584	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:O/PNarQrFWH/SALoDATRxhetTEA10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:P28798	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2365205|ensembl:ENSMUSP00000159379	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:grn_mouse(display_long)|uniprotkb:Grn(gene name)|psi-mi:Grn(display_short)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin/granulin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_032201.2|ensembl:ENSMUSG00000034708(gene)|ensembl:ENSMUST00000239431(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007566"(embryo implantation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060179"(male mating behavior)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098793"(presynapse)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905671"(regulation of lysosome organization)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28798|reactome:R-MMU-6798695	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:2nKMRNqLyZN/IXAvz1zMzDCpDmg10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9Z0Y1	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-2552776|ensembl:ENSMUSP00000030158|uniprotkb:Q9CR43|uniprotkb:Q9D039	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dctn3_mouse(display_long)|uniprotkb:Dynactin light chain p24(gene name synonym)|uniprotkb:Dctn3(gene name)|psi-mi:Dctn3(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_001153037.1|refseq:NP_058586.3|ensembl:ENSMUSG00000028447(gene)|ensembl:ENSMUST00000030158(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR009991(Dynactin subunit p22)|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:BjcdhIIVk+9CQjJ1I4VfmjHRkAE10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q8CH18	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-645246|uniprotkb:Q6AXC9|uniprotkb:Q6PAR2|uniprotkb:Q80XE4|uniprotkb:Q8BJY0|uniprotkb:Q8BVN2|uniprotkb:Q8CGG1|uniprotkb:Q9CSR5|uniprotkb:Q05BR1|uniprotkb:Q05DK6|ensembl:ENSMUSP00000020268|ensembl:ENSMUSP00000151895	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:ccar1_mouse(display_long)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Ccar1(gene name)|psi-mi:Ccar1(display_short)|uniprotkb:Carp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27110880|imex:IM-29291-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_080477.1|refseq:XP_006514057.1|refseq:XP_006514058.1|refseq:XP_006514059.1|refseq:XP_006514060.1|refseq:XP_011241839.1|ensembl:ENSMUSG00000020074(gene)|ensembl:ENSMUST00000020268(transcript)|ensembl:ENSMUST00000219527(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8CH18|reactome:R-MMU-72163	-	-	-	figure legend:F5D|comment:this interaction occurs in soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:fipMhp0uguP4AXVte036ScUyq5g10090	rigid:BGWLjr3kXlcaXq6epKSvfZKRBjI	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14B62	uniprotkb:Q9EQH3	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-775825|uniprotkb:Q61123|ensembl:ENSMUSP00000034131	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:vps35_mouse(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:Vps35(gene name)|psi-mi:Vps35(display_short)|uniprotkb:Mem3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105812|imex:IM-29291-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	refseq:NP_075373.1|dip:DIP-32210N|ensembl:ENSMUSG00000031696(gene)|ensembl:ENSMUST00000034131(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0097422"(tubular endosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903828"(negative regulation of protein localization)|go:"GO:1905166"(negative regulation of lysosomal protein catabolic process)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|mint:Q9EQH3|rcsb pdb:6VAB|rcsb pdb:6VAC|reactome:R-MMU-3238698	-	-	-	figure legend:F5E F5F|comment:this interaction occurs in membrane and soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:dK5TqSajxrGKjiNwRjeZCV519XE10090	rigid:F/Ywzphd9HdATEAc9CUrPr0c4Ek	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14B62	uniprotkb:Q62108	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105812|imex:IM-29291-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	-	-	-	figure legend:F5E F5F|comment:this interaction occurs in membrane and soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:F/Ywzphd9HdATEAc9CUrPr0c4Ek	false	glutathione s tranferase tag:n-n|binding-associated region:847-888|his tag:n-n|mutation:870-870	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q62108	uniprotkb:Q14B62	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	intact:EBI-27105784|ensembl:ENSMUSP00000039443|uniprotkb:B1AZU9|uniprotkb:Q14B63|uniprotkb:Q8BZA5	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:pthd1_mouse(display_long)|uniprotkb:ptchd1(gene name)|psi-mi:ptchd1(display_short)	psi-mi:"MI:0096"(pull down)	Tora et al. (2017)	pubmed:29118110|imex:IM-29291	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-27105848|imex:IM-29291-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	ensembl:ENSMUSG00000041552(gene)|ensembl:ENSMUST00000038665(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021794"(thalamus development)|go:"GO:0035176"(social behavior)|go:"GO:0045202"(synapse)|go:"GO:0050890"(cognition)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098977"(inhibitory chemical synaptic transmission)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|refseq:NP_001087219.1|refseq:XP_006528856.1|refseq:XP_011246114.1	-	-	-	figure legend:F5E F5F|comment:this interaction occurs in membrane and soluble fraction|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/10/12	2021/10/25	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rogid:MishHE6CVudyWtc6ySZfH5l24p410090	rigid:NZ+HezcJm6y8MSZKgSUvKGzBess	false	-	glutathione s tranferase tag:n-n|necessary binding region:885-888|his tag:n-n|mutation:870-870	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)