#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:D3Z7H4 uniprotkb:P19491-2 intact:EBI-27056750|ensembl:ENSMUSP00000073591 intact:EBI-15817825 psi-mi:gsg1l_mouse(display_long)|uniprotkb:Gsg1l(gene name)|psi-mi:Gsg1l(display_short) psi-mi:p19491-2(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Twomey et al. (2017) pubmed:28737760|imex:IM-29171 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-27056746|wwpdb:5WEK|emdb:EMD-8819|emdb:EMD-8820|wwpdb:5WEM|emdb:EMD-8822|emdb:EMD-8821|wwpdb:5WEN|wwpdb:5WEL|imex:IM-29171-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046182(gene)|ensembl:ENSMUST00000073935(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR012478(GSG1-like)|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|refseq:NP_001094958.1 intact:EBI-77718(isoform-parent) - - - figure legend:Figure 1, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293s_gnti)|taxid:9606(HEK293S GnTI -adenovirus 5 transformed, glycosylation deficient) - 2021/07/10 2021/08/10 rogid:VEAE+rBa0SpWz7B6TVPUBLmoB+w10090 rogid:MqLMOWaIntZLxIT2xkIb/59is+w10116 rigid:NhKMpV9qNuieRR7DkNmrZw49MW8 false binding-associated region:2-238|mutation:151-151 mutation:256-256,413-413,397-406|binding-associated region:25-847 2 4 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O88602 uniprotkb:P19491-2 intact:EBI-770326|ensembl:ENSMUSP00000019290 intact:EBI-15817825 psi-mi:ccg2_mouse(display_long)|uniprotkb:Neuronal voltage-gated calcium channel gamma-2 subunit(gene name synonym)|uniprotkb:Stargazin(gene name synonym)|uniprotkb:Cacng2(gene name)|psi-mi:Cacng2(display_short)|uniprotkb:Stg(gene name synonym)|uniprotkb:Transmembrane AMPAR regulatory protein gamma-2(gene name synonym) psi-mi:p19491-2(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym) psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) Twomey et al. (2017) pubmed:28737760|imex:IM-29171 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-27058632|wwpdb:5WEO|emdb:EMD-8823|imex:IM-29171-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031609.1|dip:DIP-32457N|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016247"(channel regulator activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0050877"(nervous system process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060082"(eye blink reflex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904510"(positive regulation of protein localization to basolateral plasma membrane)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR005422(Voltage-dependent calcium channel, gamma-2 subunit)|interpro:IPR008368(Voltage-dependent calcium channel, gamma subunit)|rcsb pdb:3JXT|rcsb pdb:4X3H|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5WEO|reactome:R-MMU-112308|reactome:R-MMU-399719|reactome:R-MMU-5682910|ensembl:ENSMUSG00000019146(gene)|ensembl:ENSMUST00000019290(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane) intact:EBI-77718(isoform-parent) - - - figure legend:Figure 2, Figure 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293s_gnti)|taxid:9606(HEK293S GnTI -adenovirus 5 transformed, glycosylation deficient) - 2021/07/10 2021/08/10 rogid:horuxO013U9eKJYCTV7fS8OC0BY10090 rogid:MqLMOWaIntZLxIT2xkIb/59is+w10116 rigid:tr5p/JN5d0ZWwOL8nD4c2U0AC08 false mutation:48-48 mutation:256-256,413-413,397-406|binding-associated region:25-847 4 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:2287"(identification by structure determination)