#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86SX6-PRO_0000141650 uniprotkb:Q9Y3E2 intact:EBI-27823755 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036328|imex:IM-29094-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049910(chain-parent) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - chain-seq-start:32|chain-seq-end:157 - figure legend:Fig 6 Supp. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rigid:qA04pve5XOlnlK+k7cDANO/wcKM false - sufficient binding region:21-137|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q9Y3E2 intact:EBI-25647592 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036338|imex:IM-29094-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig 6 Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 - false - sufficient binding region:21-137|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3E2 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 intact:EBI-27823755 psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036338|imex:IM-29094-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 6 Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:21-137|15n label:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86SX6-PRO_0000141650 uniprotkb:Q53S33 intact:EBI-27823755 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036349|imex:IM-29094-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049910(chain-parent) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - chain-seq-start:32|chain-seq-end:157 - figure legend:Fig 6 Supp. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rigid:PFvqwLHe4BBtEkXU1ecniu27EXM false - sufficient binding region:27-107|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q53S33 intact:EBI-25647592 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036359|imex:IM-29094-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - - - figure legend:Fig 6 Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 - false - sufficient binding region:27-107|15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53S33 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 intact:EBI-27823755 psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036359|imex:IM-29094-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 6 Supp. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:27-107|15n label:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86SX6-PRO_0000141650 uniprotkb:Q9Y3E2 intact:EBI-27823755 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036370|imex:IM-29094-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049910(chain-parent) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - chain-seq-start:32|chain-seq-end:157 - figure legend:Fig 6 Supp. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rigid:qA04pve5XOlnlK+k7cDANO/wcKM false 15n label:?-? sufficient binding region:21-137 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q9Y3E2 intact:EBI-25647592 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036382|imex:IM-29094-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig 6 Supp. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 - false - sufficient binding region:21-137 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3E2 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 intact:EBI-27823755 psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036382|imex:IM-29094-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 6 Supp. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:21-137 15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86SX6-PRO_0000141650 uniprotkb:Q53S33 intact:EBI-27823755 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036395|imex:IM-29094-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1049910(chain-parent) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - chain-seq-start:32|chain-seq-end:157 - figure legend:Fig 6 Supp. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rigid:PFvqwLHe4BBtEkXU1ecniu27EXM false 15n label:?-? sufficient binding region:27-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q53S33 intact:EBI-25647592 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036407|imex:IM-29094-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - - - figure legend:Fig 6 Supp. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 - false - sufficient binding region:27-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53S33 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 intact:EBI-27823755 psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036407|imex:IM-29094-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 6 Supp. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:27-107 15n label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q9Y3E2 intact:EBI-25647592 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036426|imex:IM-29094-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig 7A, Fig.7 Supp. 1A, 1B|comment:"The cluster coordinated by the GLRX5-BOLA1 hetero-dimer was stable against reduction by dithionite (CHEBI:33487)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 - false - sufficient binding region:30-137 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3E2 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 intact:EBI-27823755 psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036426|imex:IM-29094-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 7A, Fig.7 Supp. 1A, 1B|comment:"The cluster coordinated by the GLRX5-BOLA1 hetero-dimer was stable against reduction by dithionite (CHEBI:33487)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:30-137 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q53S33 intact:EBI-25647592 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:0016"(circular dichroism) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036502|imex:IM-29094-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - - - figure legend:Fig 7B-D Fig.7 Supp. 1C,1D|antagonist:"Dithionite (CHEBI:33487)"|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 - false - sufficient binding region:25-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53S33 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 intact:EBI-27823755 psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036502|imex:IM-29094-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig 7B-D Fig.7 Supp. 1C,1D|antagonist:"Dithionite (CHEBI:33487)"|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:25-107 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q9Y3E2 intact:EBI-25647592 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036818|imex:IM-29094-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig.7 Supp. 2A,|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 - false - sufficient binding region:30-137 - 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3E2 uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 intact:EBI-27823755 psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27036818|imex:IM-29094-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig.7 Supp. 2A,|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false sufficient binding region:30-137 - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:33737" uniprotkb:Q86SX6-PRO_0000141650 intact:EBI-25647592 intact:EBI-27823755 psi-mi:"di-mu-sulfido-diiron(2+)"(display_short)|psi-mi:"CHEBI:33737"(display_long)|intact:"[2Fe-2S](2+)"(synonym)|intact:"[Fe2(mu-S)2](2+)"(synonym)|intact:"[Fe2S2](2+)"(synonym)|intact:"di-mu-sulfido-diiron(2+)"(iupac name)|intact:"di-mu-sulfido-diiron(III)"(iupac name) psi-mi:q86sx6-pro_0000141650(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037335|imex:IM-29094-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1049910(chain-parent) - - chain-seq-start:32|chain-seq-end:157 figure legend:Fig.7 Supp. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/16 2021/11/30 - rogid:bJhT72wWd7VfsAaRTwQjVTM+3cQ9606 - false - - - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:64607" uniprotkb:Q53S33 intact:EBI-9028779 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:fe4s4 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:64607"(display_long)|intact:4 iron, 4 sulfur cluster(synonym) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037463|imex:IM-29094-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - - - figure legend:Fig.7 Supp. 3A, 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:8.4x10^-7(molar) 2021/07/16 2021/07/29 - rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 - false - fluorescent dye label:?-?|sufficient binding region:25-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q53S33 uniprotkb:Q9UMS0 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 intact:EBI-725252|uniprotkb:Q53QE5|uniprotkb:Q6VNZ8|uniprotkb:Q7Z5B1|uniprotkb:Q7Z5B2|uniprotkb:Q9Y322|uniprotkb:B4DUL9|ensembl:ENSP00000387219 psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:nfu1_human(display_long)|uniprotkb:HIRA-interacting protein 5(gene name synonym)|uniprotkb:NFU1(gene name)|psi-mi:NFU1(display_short)|uniprotkb:CGI-33(orf name)|uniprotkb:HIRIP5(gene name synonym) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037463|imex:IM-29094-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 refseq:NP_001002755.1|refseq:NP_056515.2|refseq:NP_001002756.1|ensembl:ENSG00000169599(gene)|ensembl:ENST00000410022(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:2LTM|rcsb pdb:2M5O|refseq:XP_016859297.1 - - - figure legend:Fig.7 Supp. 3A, 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:8.4x10^-7(molar) 2021/07/16 2021/07/29 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rogid:ilyUYSw8tpfn8DDWGsj96O6f7jk9606 - false fluorescent dye label:?-?|sufficient binding region:25-107 sufficient binding region:57-254 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:64607" uniprotkb:Q9Y3E2 intact:EBI-9028779 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:fe4s4 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:64607"(display_long)|intact:4 iron, 4 sulfur cluster(synonym) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037473|imex:IM-29094-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig.7 Supp. 3A, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.14x10^-6(molar) 2021/07/16 2021/07/29 - rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 - false - sufficient binding region:30-137|fluorescent dye label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y3E2 uniprotkb:Q9UMS0 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 intact:EBI-725252|uniprotkb:Q53QE5|uniprotkb:Q6VNZ8|uniprotkb:Q7Z5B1|uniprotkb:Q7Z5B2|uniprotkb:Q9Y322|uniprotkb:B4DUL9|ensembl:ENSP00000387219 psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:nfu1_human(display_long)|uniprotkb:HIRA-interacting protein 5(gene name synonym)|uniprotkb:NFU1(gene name)|psi-mi:NFU1(display_short)|uniprotkb:CGI-33(orf name)|uniprotkb:HIRIP5(gene name synonym) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037473|imex:IM-29094-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 refseq:NP_001002755.1|refseq:NP_056515.2|refseq:NP_001002756.1|ensembl:ENSG00000169599(gene)|ensembl:ENST00000410022(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:2LTM|rcsb pdb:2M5O|refseq:XP_016859297.1 - - - figure legend:Fig.7 Supp. 3A, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.14x10^-6(molar) 2021/07/16 2021/07/29 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rogid:ilyUYSw8tpfn8DDWGsj96O6f7jk9606 - false sufficient binding region:30-137|fluorescent dye label:?-? sufficient binding region:32-157 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UMS0 uniprotkb:Q53S33 intact:EBI-725252|uniprotkb:Q53QE5|uniprotkb:Q6VNZ8|uniprotkb:Q7Z5B1|uniprotkb:Q7Z5B2|uniprotkb:Q9Y322|uniprotkb:B4DUL9|ensembl:ENSP00000387219 intact:EBI-12086950|ensembl:ENSP00000331369|uniprotkb:G3XAB0 psi-mi:nfu1_human(display_long)|uniprotkb:HIRA-interacting protein 5(gene name synonym)|uniprotkb:NFU1(gene name)|psi-mi:NFU1(display_short)|uniprotkb:CGI-33(orf name)|uniprotkb:HIRIP5(gene name synonym) psi-mi:bola3_human(display_long)|uniprotkb:BOLA3(gene name)|psi-mi:BOLA3(display_short) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037487|imex:IM-29094-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002755.1|refseq:NP_056515.2|refseq:NP_001002756.1|ensembl:ENSG00000169599(gene)|ensembl:ENST00000410022(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:2LTM|rcsb pdb:2M5O|refseq:XP_016859297.1 ensembl:ENSG00000163170(gene)|ensembl:ENST00000327428(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|rcsb pdb:2NCL|refseq:NP_997717.2|refseq:NP_001030582.1 - - - figure legend:Fig.7 Supp. 3A, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.57x10^-6(molar) 2021/07/16 2021/07/16 rogid:ilyUYSw8tpfn8DDWGsj96O6f7jk9606 rogid:/Zkky+uKh+obgxxQRUoDTPiaacA9606 rigid:JK4NJK8n4wtHhvJ9gxvD6H6mAYE false sufficient binding region:57-254 fluorescent dye label:?-?|sufficient binding region:25-107 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UMS0 uniprotkb:Q9Y3E2 intact:EBI-725252|uniprotkb:Q53QE5|uniprotkb:Q6VNZ8|uniprotkb:Q7Z5B1|uniprotkb:Q7Z5B2|uniprotkb:Q9Y322|uniprotkb:B4DUL9|ensembl:ENSP00000387219 intact:EBI-1049556|uniprotkb:Q5QNY0|uniprotkb:B2R7K2|uniprotkb:D3DUZ4|ensembl:ENSP00000358146|ensembl:ENSP00000358148|ensembl:ENSP00000358149 psi-mi:nfu1_human(display_long)|uniprotkb:HIRA-interacting protein 5(gene name synonym)|uniprotkb:NFU1(gene name)|psi-mi:NFU1(display_short)|uniprotkb:CGI-33(orf name)|uniprotkb:HIRIP5(gene name synonym) psi-mi:bola1_human(display_long)|uniprotkb:BOLA1(gene name)|psi-mi:BOLA1(display_short)|uniprotkb:CGI-143(orf name)|uniprotkb:hBolA(gene name synonym) psi-mi:"MI:1247"(microscale thermophoresis) Uzarska et al. (2016) imex:IM-29094|pubmed:27532772 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-27037498|imex:IM-29094-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002755.1|refseq:NP_056515.2|refseq:NP_001002756.1|ensembl:ENSG00000169599(gene)|ensembl:ENST00000410022(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:2LTM|rcsb pdb:2M5O|refseq:XP_016859297.1 refseq:NP_057158.1|ensembl:ENSG00000178096(gene)|ensembl:ENST00000369150(transcript)|ensembl:ENST00000369152(transcript)|ensembl:ENST00000369153(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9Y3E2|rcsb pdb:5LCI|refseq:NP_001307954.1|refseq:NP_001307955.1|refseq:XP_006711411.1 - - - figure legend:Fig.7 Supp. 3A, 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.59x10^-6(molar) 2021/07/16 2021/07/16 rogid:ilyUYSw8tpfn8DDWGsj96O6f7jk9606 rogid:zwuatrT4uNhiEo9giPSvjsyUu0w9606 rigid:S2ziy20ZsUI5z4k2hBELWELEFSE false sufficient binding region:32-157 sufficient binding region:30-137|fluorescent dye label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)