#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16056 uniprotkb:Q9R0M0 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8294754|uniprotkb:A2AEE7|intact:MINT-5202369|uniprotkb:Q9Z2R4|uniprotkb:Q99K26|ensembl:ENSMUSP00000088046 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:celr2_mouse(display_long)|uniprotkb:Celsr2(gene name)|psi-mi:Celsr2(display_short)|uniprotkb:Flamingo homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_059088.2|ensembl:ENSMUST00000090558(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003341"(cilium movement)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|ensembl:ENSMUSG00000068740(gene)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021591"(ventricular system development)|go:"GO:0021999"(neural plate anterior/posterior regionalization)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001791(Laminin G)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR017981|interpro:IPR020894|interpro:IPR032471|interpro:IPR036445 - - comment:mint|function:Receptor that may have an important role in cell/cell signaling during nervous system formation figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wPmtsYNVGZrtMfXD5UyeAIjTm7Y10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q921M7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8321269|intact:MINT-4094888|ensembl:ENSMUSP00000066359|ensembl:ENSMUSP00000132486|ensembl:ENSMUSP00000154320 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cyrib_mouse(display_long)|uniprotkb:Cyrib(gene name)|psi-mi:Cyrib(display_short)|uniprotkb:Cyri(gene name synonym)|uniprotkb:Fam49b(gene name synonym)|uniprotkb:Protein FAM49B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:XP_011243867.1|refseq:XP_011243865.1|refseq:NP_659095.1|refseq:XP_006520824.1|refseq:XP_006520826.1|refseq:XP_006520827.1|ensembl:ENSMUSG00000022378(gene)|ensembl:ENSMUST00000063838(transcript)|ensembl:ENSMUST00000164532(transcript)|ensembl:ENSMUST00000228226(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0023030"(MHC class Ib protein binding, via antigen binding groove)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000568"(positive regulation of memory T cell activation)|interpro:IPR009828(Protein of unknown function DUF1394)|interpro:IPR039789|mint:Q921M7|rcsb pdb:7AJL|reactome:R-MMU-114608 - - comment:mint figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:TKMOyqWPIodr3CdX53oO2MiyXHY10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P35822 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8400014|intact:MINT-4109163|ensembl:ENSMUSP00000126279 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ptprk_mouse(display_long)|uniprotkb:Ptprk(gene name)|psi-mi:Ptprk(display_short)|uniprotkb:Ptpk(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_033009.1|ensembl:ENSMUSG00000019889(gene)|ensembl:ENSMUST00000166468(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0031256"(leading edge membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048041"(focal adhesion assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|mint:P35822|reactome:R-MMU-182971 - - comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTP-kappa figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:UNbFiSC1wMQ/Cb9a+q/4FKfy3+k10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2AHC3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8315846|ensembl:ENSMUSP00000088812|ensembl:ENSMUSP00000139028|uniprotkb:Q7TQF8|intact:MINT-4115002|uniprotkb:Q8CBV3 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:camp1_mouse(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000026933(gene)|ensembl:ENSMUST00000091268(transcript)|ensembl:ENSMUST00000183461(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR038209|mint:A2AHC3|interpro:IPR036872|refseq:NP_001263288.1|refseq:NP_001263290.1|refseq:NP_001263289.1 - - comment:mint figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:+1co+J8WhfPuX8PMFq2C2m1Wm7o10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P97772 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-396863|uniprotkb:Q6AXG4|uniprotkb:Q9EPV6|ensembl:ENSMUSP00000037255 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:grm1_mouse(display_long)|uniprotkb:Grm1(gene name)|psi-mi:Grm1(display_short)|uniprotkb:Gprc1a(gene name synonym)|uniprotkb:Mglur1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001107805.1|refseq:NP_058672.1|refseq:XP_006512612.1|ensembl:ENSMUSG00000019828(gene)|ensembl:ENSMUST00000044306(transcript)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0038037"(G protein-coupled receptor dimeric complex)|go:"GO:0038038"(G protein-coupled receptor homodimeric complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098872"(G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001256(GPCR, family 3, metabotropic glutamate receptor 1)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|mint:P97772|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:WJAWpEEcB6PLmPlnp8R9/mV+rW410090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P97379-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112526|ensembl:ENSMUSP00000108752|ensembl:ENSMUSP00000132469 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:p97379-2(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3bp2(gene name)|psi-mi:G3bp2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-8319813(isoform-parent)|ensembl:ENSMUSG00000029405(gene)|ensembl:ENSMUST00000113127(transcript)|ensembl:ENSMUST00000167918(transcript) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:jZpRKq3FiEY9BGA9e2XZ79QjXiE10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80Y17 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112631|ensembl:ENSMUSP00000104359|uniprotkb:Q61856|uniprotkb:Q7TNV3|uniprotkb:Q8BN92 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:l2gl1_mouse(display_long)|uniprotkb:Mgl-1(gene name synonym)|uniprotkb:Mlgl(gene name synonym)|uniprotkb:Llgl1(gene name)|psi-mi:Llgl1(display_short)|uniprotkb:Llglh(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000020536(gene)|ensembl:ENSMUST00000108719(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|refseq:NP_001152876.1|refseq:NP_001152877.1|refseq:NP_032528.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Ctu5jp4t+tQPRbAYPhuBdR7Mr6Y10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9D2Y5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112612|uniprotkb:Q3U0B6|uniprotkb:Q544B6|uniprotkb:Q8CHQ3 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:snx20_mouse(display_long)|uniprotkb:Snx20(gene name)|psi-mi:Snx20(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|refseq:NP_082116.1|refseq:XP_006531434.1|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937|interpro:IPR011990(Tetratricopeptide-like helical) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:HWIhkjQ+Oz7w1RQ0hJk3TuYRmRM10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9CR57 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-773925|uniprotkb:Q9D8Q1|ensembl:ENSMUSP00000131489 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:rl14_mouse(display_long)|uniprotkb:Rpl14(gene name)|psi-mi:Rpl14(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_080250.1|ensembl:ENSMUSG00000025794(gene)|ensembl:ENSMUST00000165532(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR039660|interpro:IPR041985|mint:Q9CR57|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Z9bOUoDfmZzjfVXr5d6nHXMv6qA10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A0JP53 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112586|ensembl:ENSMUSP00000154554 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a0jp53_mouse(display_long)|uniprotkb:Dgkh(gene name)|psi-mi:Dgkh(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000034731(gene)|ensembl:ENSMUST00000228362(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046486"(glycerolipid metabolic process)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR037607|refseq:NP_001240695.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:7suyMIZplZXRJiUGjAEloj+QLzg10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q14BI2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-5281533|ensembl:ENSMUSP00000023959 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:grm2_mouse(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001153825.1|ensembl:ENSMUSG00000023192(gene)|ensembl:ENSMUST00000023959(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:Q14BI2|reactome:R-MMU-418594|reactome:R-MMU-420499 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:51Vq4ZsTylhat6thFK/8MBMIKUI10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P21279 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q69ZH9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-26472113|uniprotkb:Q8BNY7|uniprotkb:Q9JJD6 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:rhg23_mouse(display_long)|uniprotkb:Arhgap23(gene name)|psi-mi:Arhgap23(display_short)|uniprotkb:Kiaa1501(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 23(gene name synonym)|uniprotkb:MNCb-1301(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|reactome:R-MMU-8980692|reactome:R-MMU-9013149|mint:Q69ZH9|refseq:NP_067468.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR041489|interpro:IPR036034|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR041681|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:KTCeDuLV+qHtInBwC3PzUFi0VO810090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9D486 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112567|ensembl:ENSMUSP00000130264|uniprotkb:Q69ZD2|uniprotkb:Q8C3N2|uniprotkb:Q8K148 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cmip_mouse(display_long)|uniprotkb:Cmip(gene name)|psi-mi:Cmip(display_short)|uniprotkb:Kiaa1694(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000034390(gene)|ensembl:ENSMUST00000166750(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR032675|refseq:NP_001156734.1|refseq:NP_083217.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:f0OKUNN46c0byImGIvTpemu3ND810090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6VNS1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16744951|ensembl:ENSMUSP00000037909|uniprotkb:A4QPD0|uniprotkb:Q9Z2P9|uniprotkb:Q9Z2Q0 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ntrk3_mouse(display_long)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039431(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020446|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|reactome:R-MMU-388844|reactome:R-MMU-9034013|reactome:R-MMU-9034793|reactome:R-MMU-9603381|refseq:NP_032772.3|refseq:NP_877961.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:awHq4B+I8bd3A6XndEgDYNbRS5Y10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3U0M1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6160720|uniprotkb:Q3UU81|uniprotkb:Q69Z79|uniprotkb:Q6NS50|uniprotkb:Q8CD01|uniprotkb:Q8CFV8|uniprotkb:Q9D8R6 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:tppc9_mouse(display_long)|uniprotkb:Trappc9(gene name)|psi-mi:Trappc9(display_short)|uniprotkb:Kiaa1882(gene name synonym)|uniprotkb:Nibp(gene name synonym)|uniprotkb:NIK- and IKBKB-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) mint:Q3U0M1|refseq:NP_001158113.1|refseq:NP_001158114.1|refseq:NP_001158115.1|refseq:NP_083916.1|refseq:NP_850993.2|interpro:IPR013935(Transport protein Trs120)|refseq:XP_006521590.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030008"(TRAPP complex)|go:"GO:0030182"(neuron differentiation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|reactome:R-MMU-204005|reactome:R-MMU-8876198 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:4o6Vzu9Mu9hWN7CZ+ifMfOffaGk10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q62108 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UH66 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16718850|uniprotkb:Q3V387|uniprotkb:Q6PAN9|uniprotkb:Q6ZPI6|uniprotkb:Q7TNS1|uniprotkb:Q811F2 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:wnk2_mouse(display_long)|uniprotkb:Protein kinase lysine-deficient 2(gene name synonym)|uniprotkb:Protein kinase with no lysine 2(gene name synonym)|uniprotkb:Wnk2(gene name)|psi-mi:Wnk2(display_short)|uniprotkb:Kiaa1760(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) reactome:R-MMU-2672351|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|refseq:NP_001277240.1|refseq:NP_001277242.1|refseq:NP_083637.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:XZP3MNd8Qw5pnZbyCSN4bKg5GBA10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UU96 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-10729569|uniprotkb:B2RY49|uniprotkb:Q4V9U7|uniprotkb:Q6ZQA9|uniprotkb:Q8R495|ensembl:ENSMUSP00000095059 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:mrcka_mouse(display_long)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Kiaa0451(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001333733.1|ensembl:ENSMUSG00000026490(gene)|ensembl:ENSMUST00000097450(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Gwxi5/9sLhSU4uqjoMrwxzv0yoU10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q03141 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6271614|ensembl:ENSMUSP00000152483|uniprotkb:Q3TM40|uniprotkb:Q3V1U3|uniprotkb:Q8C6G9|uniprotkb:Q8R375|uniprotkb:Q9JKE4 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:mark3_mouse(display_long)|uniprotkb:Mark3(gene name)|psi-mi:Mark3(display_short)|uniprotkb:Emk2(gene name synonym)|uniprotkb:Mpk10(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)|uniprotkb:MPK-10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000007411(gene)|ensembl:ENSMUST00000221459(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|rcsb pdb:1UL7|rcsb pdb:1V5S|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|refseq:XP_006515578.1|refseq:NP_067491.2|refseq:NP_073712.2 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:HW82JxS22iNaXpgoeug0FOrMRmM10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q06890 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-774758|ensembl:ENSMUSP00000022616 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:clus_mouse(display_long)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:Clustrin(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Clu(gene name)|psi-mi:Clu(display_short)|uniprotkb:Apoj(gene name synonym)|uniprotkb:Msgp-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_038520.2|refseq:XP_006518567.1|ensembl:ENSMUSG00000022037(gene)|ensembl:ENSMUST00000022616(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0017038"(protein import)|go:"GO:0030426"(growth cone)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0071944"(cell periphery)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:Q06890|reactome:R-MMU-114608|reactome:R-MMU-166665|reactome:R-MMU-6803157|reactome:R-MMU-977606|go:"GO:0042583"(chromaffin granule) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wP6AESslzICF3ojv9a+vJUn61VA10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q8I9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16732044|ensembl:ENSMUSP00000084454|uniprotkb:Q4VA57|uniprotkb:Q5DTL4|uniprotkb:Q8BIW6|uniprotkb:Q8BUA0|uniprotkb:Q8CG91 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:fry_mouse(display_long)|uniprotkb:Fry(gene name)|psi-mi:Fry(display_short)|uniprotkb:Kiaa4143(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000056602(gene)|ensembl:ENSMUST00000087204(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005938"(cell cortex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031175"(neuron projection development)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|mint:E9Q8I9|refseq:NP_766475.2|refseq:XP_006504993.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:fvduzhqkwcM9qmnWvPWAA1W8HqI10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6ZPQ6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16744915|ensembl:ENSMUSP00000124111|uniprotkb:Q9R1P5 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pitm2_mouse(display_long)|uniprotkb:Pitpnm2(gene name)|psi-mi:Pitpnm2(display_short)|uniprotkb:Drosophila retinal degeneration B homolog 2(gene name synonym)|uniprotkb:Kiaa1457(gene name synonym)|uniprotkb:Nir3(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 2(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000029406(gene)|ensembl:ENSMUST00000161938(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0044297"(cell body)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR023214|interpro:IPR023393|interpro:IPR031315|interpro:IPR036412|mint:Q6ZPQ6|reactome:R-MMU-1483226|interpro:IPR004177(DDHD)|refseq:NP_001276401.1|refseq:NP_035386.1|refseq:XP_017176233.1 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:4zrvxwjon6qsbpA3n5INhmMp/KQ10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q5XJV6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16726286|uniprotkb:A6BLZ0|uniprotkb:Q52KF1 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:lmtk3_mouse(display_long)|uniprotkb:Apoptosis-associated tyrosine kinase 3(gene name synonym)|uniprotkb:Lemur tyrosine kinase 3(gene name synonym)|uniprotkb:Lmtk3(gene name)|psi-mi:Lmtk3(display_short)|uniprotkb:Aatyk3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|mint:Q5XJV6|refseq:NP_001005511.2|refseq:NP_001277919.1|refseq:XP_006541027.1|refseq:XP_017177816.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:FJgk1CZB0wgIbl5dhC81Wy7TRJE10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61290 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-770918 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cac1e_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.3(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 6(gene name synonym)|uniprotkb:Brain calcium channel II(gene name synonym)|uniprotkb:Cacna1e(gene name)|psi-mi:Cacna1e(display_short)|uniprotkb:Cach6(gene name synonym)|uniprotkb:Cacnl1a6(gene name synonym)|uniprotkb:Cchra1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR005449(Voltage-dependent calcium channel, R-type, alpha-1 subunit)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR027359|interpro:IPR031649|go:"GO:0001662"(behavioral fear response)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0042596"(fear response)|go:"GO:0043204"(perikaryon)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050877"(nervous system process)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090273"(regulation of somatostatin secretion)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|reactome:R-MMU-112308|reactome:R-MMU-422356|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042593"(glucose homeostasis)|mint:Q61290 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:EaL/xQzdjloSLb88yMW1gqddCjM10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8BNA6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-9249482|uniprotkb:Q08ED4|ensembl:ENSMUSP00000148968 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:fat3_mouse(display_long)|uniprotkb:Fat3(gene name)|psi-mi:Fat3(display_short)|uniprotkb:Gm1132(gene name synonym)|uniprotkb:Gm510(gene name synonym)|uniprotkb:FAT tumor suppressor homolog 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000074505(gene)|ensembl:ENSMUST00000217308(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001764"(neuron migration)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:6qYzKNfptfMq3+tixy7T601dT/U10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3V1U8 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112556|ensembl:ENSMUSP00000046191 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:elmd1_mouse(display_long)|uniprotkb:Elmod1(gene name)|psi-mi:Elmod1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000041986(gene)|ensembl:ENSMUST00000048409(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR030722|refseq:NP_808437.2 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:UV8Y2XLxUuYVJGo83ou5ZF1zMPQ10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q4KUS2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-775397|uniprotkb:E9QKH9|uniprotkb:Q3UHG2|ensembl:ENSMUSP00000030170 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:un13a_mouse(display_long)|uniprotkb:Munc13-1(gene name synonym)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001025044.2|ensembl:ENSMUSG00000034799(gene)|ensembl:ENSMUST00000030170(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030507"(spectrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:B5Qv8BCg48XDED/99G5RS7g5Fn410090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q922P8 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112532|ensembl:ENSMUSP00000025645|uniprotkb:Q69ZF9|uniprotkb:Q8BX93 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:t132a_mouse(display_long)|uniprotkb:HSPA5-binding protein 1(gene name synonym)|uniprotkb:Tmem132a(gene name)|psi-mi:Tmem132a(display_short)|uniprotkb:Kiaa1583(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000024736(gene)|ensembl:ENSMUST00000025645(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043069"(negative regulation of programmed cell death)|interpro:IPR026307|interpro:IPR031435|interpro:IPR031436|interpro:IPR031437|reactome:R-MMU-381426|reactome:R-MMU-8957275|refseq:NP_598565.2 - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:1M8S011dRWOsRNTTEBzMRS1tDQE10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9WTS5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16734841|uniprotkb:Q5NBW7|uniprotkb:Q5NBW8|uniprotkb:Q80TJ0|uniprotkb:Q9JLC0|uniprotkb:Q9QYZ1 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ten2_mouse(display_long)|uniprotkb:Protein Odd Oz/ten-m homolog 2(gene name synonym)|uniprotkb:Tenascin-M2(gene name synonym)|uniprotkb:Teneurin transmembrane protein 2(gene name synonym)|uniprotkb:Tenm2(gene name)|psi-mi:Tenm2(display_short)|uniprotkb:Kiaa1127(gene name synonym)|uniprotkb:Odz2(gene name synonym)|uniprotkb:Tnm2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27112678|imex:IM-29320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016605"(PML body)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR022385|interpro:IPR027689|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR028916|interpro:IPR006530(YD repeat) - - - figure legend:ST1|comment:Co-IP/MS with HGF stimulation|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/27 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wQ0xOO0bqzQ0E++dsnlaGkXJyis10090 rigid:CyIgXo/A2J21or6PdwLja+zSvWM false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:O35954 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8327777|intact:MINT-4104925|ensembl:ENSMUSP00000054309|ensembl:ENSMUSP00000097599 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pitm1_mouse(display_long)|uniprotkb:Pitpnm1(gene name)|psi-mi:Pitpnm1(display_short)|uniprotkb:Dres9(gene name synonym)|uniprotkb:Mpt1(gene name synonym)|uniprotkb:Nir2(gene name synonym)|uniprotkb:Pitpnm(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 1(gene name synonym)|uniprotkb:Mpt-1(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 2(gene name synonym)|uniprotkb:Drosophila retinal degeneration B homolog 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032877.1|ensembl:ENSMUSG00000024851(gene)|ensembl:ENSMUST00000049658(transcript)|ensembl:ENSMUST00000100022(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015031"(protein transport)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044297"(cell body)|go:"GO:0070300"(phosphatidic acid binding)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR023393|interpro:IPR031315|interpro:IPR036412|mint:O35954|reactome:R-MMU-1483226 - - comment:mint|function:"Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions" figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:FOv7BJbaEF2IBuGzhURvp2lPVRs10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61271 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8571317|ensembl:ENSMUSP00000000544|intact:MINT-2842316 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:acv1b_mouse(display_long)|uniprotkb:Acvr1b(gene name)|psi-mi:Acvr1b(display_short)|uniprotkb:Alk4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase receptor R2(gene name synonym)|uniprotkb:Activin receptor-like kinase 4(gene name synonym)|uniprotkb:Activin receptor type IB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046545"(development of primary female sexual characteristics)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048179"(activin receptor complex)|go:"GO:0048185"(activin binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003605(TGF beta receptor, GS motif)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q61271|reactome:R-MMU-1502540|go:"GO:0034711"(inhibin binding)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0043235"(receptor complex)|ensembl:ENSMUSG00000000532(gene)|ensembl:ENSMUST00000000544(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001942"(hair follicle development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004675"(transmembrane receptor protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007498"(mesoderm development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016361"(activin receptor activity, type I)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|refseq:NP_031421.1 - - function:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators|comment:mint figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:jKop1TxDKPoQZkHgo0iEXfFCrmM10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UTJ2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8345744|uniprotkb:Q80TS1|intact:MINT-1853612|uniprotkb:Q3USC6|uniprotkb:Q8BX47|uniprotkb:Q8CHU0|uniprotkb:Q8BLW9|intact:MINT-4116161|uniprotkb:Q8BJL6|uniprotkb:Q8BJU3 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:srbs2_mouse(display_long)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Kiaa0777(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001297636.1|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:Q3UTJ2|refseq:XP_006509449.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR001452(Src homology-3) - - comment:"fragmentation type: fragment" figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:2sKDQux/2IV7mW8l6LK36D3qlqw10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P35822 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8400014|intact:MINT-4109163|ensembl:ENSMUSP00000126279 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ptprk_mouse(display_long)|uniprotkb:Ptprk(gene name)|psi-mi:Ptprk(display_short)|uniprotkb:Ptpk(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_033009.1|ensembl:ENSMUSG00000019889(gene)|ensembl:ENSMUST00000166468(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0031256"(leading edge membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048041"(focal adhesion assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|mint:P35822|reactome:R-MMU-182971 - - comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTP-kappa figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:UNbFiSC1wMQ/Cb9a+q/4FKfy3+k10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80UG2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8057809|intact:MINT-7996686|uniprotkb:E9QN64|uniprotkb:Q8BKK9|uniprotkb:Q5DTW8|ensembl:ENSMUSP00000110748 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:plxa4_mouse(display_long)|uniprotkb:Plxna4(gene name)|psi-mi:Plxna4(display_short)|uniprotkb:Kiaa1550(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_786926.2|ensembl:ENSMUSG00000029765(gene)|ensembl:ENSMUST00000115096(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0021636"(trigeminal nerve morphogenesis)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0021784"(postganglionic parasympathetic fiber development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021793"(chemorepulsion of branchiomotor axon)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050923"(regulation of negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|rcsb pdb:5L5K|rcsb pdb:5L5L|rcsb pdb:5L5M|rcsb pdb:5L5N|rcsb pdb:7M0R|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956 - - comment:mint figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:VQbA7Dwc5J/HFFzXl4mVEbBNkNY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9R0M0 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-8294754|uniprotkb:A2AEE7|intact:MINT-5202369|uniprotkb:Q9Z2R4|uniprotkb:Q99K26|ensembl:ENSMUSP00000088046 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:celr2_mouse(display_long)|uniprotkb:Celsr2(gene name)|psi-mi:Celsr2(display_short)|uniprotkb:Flamingo homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_059088.2|ensembl:ENSMUST00000090558(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003341"(cilium movement)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|ensembl:ENSMUSG00000068740(gene)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021591"(ventricular system development)|go:"GO:0021999"(neural plate anterior/posterior regionalization)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033326"(cerebrospinal fluid secretion)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001791(Laminin G)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR017981|interpro:IPR020894|interpro:IPR032471|interpro:IPR036445 - - comment:mint|function:Receptor that may have an important role in cell/cell signaling during nervous system formation figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wPmtsYNVGZrtMfXD5UyeAIjTm7Y10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8VDD5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N - - caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P08553 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-445188|uniprotkb:A2VCT5|uniprotkb:Q0VDM8|uniprotkb:Q3HRJ6|uniprotkb:Q3TNS4|uniprotkb:Q3TPK2|uniprotkb:Q61961|uniprotkb:Q8BQ20 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:nfm_mouse(display_long)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032717.2|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|interpro:IPR027697|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|mint:P08553 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:2HBUZIEhbbrfamAhbq7gyuRUaTk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80Z38-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16737571|ensembl:ENSMUSP00000146440 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q80z38-3(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)|uniprotkb:Kiaa1022(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-770338(isoform-parent)|ensembl:ENSMUSG00000037541(gene)|ensembl:ENSMUST00000146006(transcript) - - isoform-comment:Contains a phosphoserine at position 162. figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:nSuK3V81EK4IT07tk6V8ZgrwB2U10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q922P8 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112532|ensembl:ENSMUSP00000025645|uniprotkb:Q69ZF9|uniprotkb:Q8BX93 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:t132a_mouse(display_long)|uniprotkb:HSPA5-binding protein 1(gene name synonym)|uniprotkb:Tmem132a(gene name)|psi-mi:Tmem132a(display_short)|uniprotkb:Kiaa1583(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000024736(gene)|ensembl:ENSMUST00000025645(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043069"(negative regulation of programmed cell death)|interpro:IPR026307|interpro:IPR031435|interpro:IPR031436|interpro:IPR031437|reactome:R-MMU-381426|reactome:R-MMU-8957275|refseq:NP_598565.2 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:1M8S011dRWOsRNTTEBzMRS1tDQE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q923T9-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16736709|ensembl:ENSMUSP00000098398 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q923t9-3(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-771638(isoform-parent)|ensembl:ENSMUSG00000021820(gene)|ensembl:ENSMUST00000100837(transcript) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:XK4XzLpRHb5Pxofk3qXJaodZkMQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2CG49 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80Y17 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27112631|ensembl:ENSMUSP00000104359|uniprotkb:Q61856|uniprotkb:Q7TNV3|uniprotkb:Q8BN92 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:l2gl1_mouse(display_long)|uniprotkb:Mgl-1(gene name synonym)|uniprotkb:Mlgl(gene name synonym)|uniprotkb:Llgl1(gene name)|psi-mi:Llgl1(display_short)|uniprotkb:Llglh(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000020536(gene)|ensembl:ENSMUST00000108719(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035090"(maintenance of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR013905("Lethal giant larvae (Lgl) like, C-terminal")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|refseq:NP_001152876.1|refseq:NP_001152877.1|refseq:NP_032528.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Ctu5jp4t+tQPRbAYPhuBdR7Mr6Y10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9ESN9-5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117483|ensembl:ENSMUSP00000110883 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q9esn9-5(display_long)|uniprotkb:JNK MAP kinase scaffold protein 3(gene name synonym)|uniprotkb:JNK/SAPK-associated protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 3(gene name synonym)|uniprotkb:Sunday driver 2(gene name synonym)|uniprotkb:Mapk8ip3(gene name)|psi-mi:Mapk8ip3(display_short)|uniprotkb:Jip3(gene name synonym)|uniprotkb:Jsap1(gene name synonym)|uniprotkb:Syd2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000024163(gene)|ensembl:ENSMUST00000115228(transcript)|intact:EBI-301496(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:/9DrGauUhTGTsrFFXw2aglOuT8Y10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6VNS1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16744951|ensembl:ENSMUSP00000037909|uniprotkb:A4QPD0|uniprotkb:Q9Z2P9|uniprotkb:Q9Z2Q0 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ntrk3_mouse(display_long)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039431(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020446|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|reactome:R-MMU-388844|reactome:R-MMU-9034013|reactome:R-MMU-9034793|reactome:R-MMU-9603381|refseq:NP_032772.3|refseq:NP_877961.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:awHq4B+I8bd3A6XndEgDYNbRS5Y10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2AHC4 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118150|ensembl:ENSMUSP00000117203 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a2ahc4_mouse(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000026933(gene)|ensembl:ENSMUST00000134882(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031175"(neuron projection development)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:yv6B3Szp9QZx71rkdWpRg/KJB5410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6ZPQ6-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16737449|ensembl:ENSMUSP00000083292|ensembl:ENSMUSP00000124740 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q6zpq6-2(display_long)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 2(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 3(gene name synonym)|uniprotkb:Drosophila retinal degeneration B homolog 2(gene name synonym)|uniprotkb:Pitpnm2(gene name)|psi-mi:Pitpnm2(display_short)|uniprotkb:Kiaa1457(gene name synonym)|uniprotkb:Nir3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000029406(gene)|ensembl:ENSMUST00000086123(transcript)|ensembl:ENSMUST00000162812(transcript)|intact:EBI-16744915(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:/Rb6E3SlDclAVBHFb6FRT6Wd1bw10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61290 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-770918 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cac1e_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.3(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 6(gene name synonym)|uniprotkb:Brain calcium channel II(gene name synonym)|uniprotkb:Cacna1e(gene name)|psi-mi:Cacna1e(display_short)|uniprotkb:Cach6(gene name synonym)|uniprotkb:Cacnl1a6(gene name synonym)|uniprotkb:Cchra1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR005449(Voltage-dependent calcium channel, R-type, alpha-1 subunit)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR027359|interpro:IPR031649|go:"GO:0001662"(behavioral fear response)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0042596"(fear response)|go:"GO:0043204"(perikaryon)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050877"(nervous system process)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090273"(regulation of somatostatin secretion)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|reactome:R-MMU-112308|reactome:R-MMU-422356|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042593"(glucose homeostasis)|mint:Q61290 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:EaL/xQzdjloSLb88yMW1gqddCjM10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q5XJV6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16726286|uniprotkb:A6BLZ0|uniprotkb:Q52KF1 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:lmtk3_mouse(display_long)|uniprotkb:Apoptosis-associated tyrosine kinase 3(gene name synonym)|uniprotkb:Lemur tyrosine kinase 3(gene name synonym)|uniprotkb:Lmtk3(gene name)|psi-mi:Lmtk3(display_short)|uniprotkb:Aatyk3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|mint:Q5XJV6|refseq:NP_001005511.2|refseq:NP_001277919.1|refseq:XP_006541027.1|refseq:XP_017177816.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:FJgk1CZB0wgIbl5dhC81Wy7TRJE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UH93 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118098|uniprotkb:Q68HV1|ensembl:ENSMUSP00000015511 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:plxd1_mouse(display_long)|uniprotkb:Plxnd1(gene name)|psi-mi:Plxnd1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_080652.2|ensembl:ENSMUSG00000030123(gene)|ensembl:ENSMUST00000015511(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR042719|go:"GO:0035904"(aorta development)|rcsb pdb:5V6R|rcsb pdb:5V6T|reactome:R-MMU-416700|reactome:R-MMU-9696270 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:pig7rzQJrektsDoVZ7XW79JvI5o10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q852 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118080|ensembl:ENSMUSP00000128891 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q852_mouse(display_long)|uniprotkb:Afdn(gene name)|psi-mi:Afdn(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000068036(gene)|ensembl:ENSMUST00000170827(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:JlSOwLdrsmLdoOPaaVDcNT3aDaE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8JZP2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-3869486|uniprotkb:E9QNQ6|ensembl:ENSMUSP00000113720 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:syn3_mouse(display_long)|uniprotkb:Syn3(gene name)|psi-mi:Syn3(display_short)|uniprotkb:Synapsin III(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_038750.2|refseq:XP_006513761.1|refseq:XP_006513762.1|refseq:XP_006513763.1|ensembl:ENSMUSG00000059602(gene)|ensembl:ENSMUST00000120638(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0045202"(synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|mint:Q8JZP2|reactome:R-MMU-181429|reactome:R-MMU-212676 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:HJPX+DeRZpwPqgIJXn7opVNHf3410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:G3X922 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118056|ensembl:ENSMUSP00000035170 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:g3x922_mouse(display_long)|uniprotkb:Dnajc13(gene name)|psi-mi:Dnajc13(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001156498.1|go:"GO:0007032"(endosome organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1902954"(regulation of early endosome to recycling endosome transport)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025640|interpro:IPR035445|interpro:IPR036869|ensembl:ENSMUSG00000032560(gene)|ensembl:ENSMUST00000035170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:GDEiBN7lIyrykPY1J25ghtZ1aDc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:F6Z0Z5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118043|ensembl:ENSMUSP00000131989 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:f6z0z5_mouse(display_long)|uniprotkb:Rem2(gene name)|psi-mi:Rem2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000022176(gene)|ensembl:ENSMUST00000168930(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR025662|interpro:IPR027417 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:ojHtUYdkjxfF8YRTMhZv+7XjzAU10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2AN08-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118031 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a2an08-3(display_long)|uniprotkb:Ubr4(gene name)|psi-mi:Ubr4(display_short)|uniprotkb:Kiaa0462(gene name synonym)|uniprotkb:Zubr1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:A2AN08-3(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:YIiuu5YhXkBWOoRnsm8wMMdeJw410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8C0T5-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16737000|ensembl:ENSMUSP00000152356 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q8c0t5-2(display_long)|uniprotkb:Sipa1l1(gene name)|psi-mi:Sipa1l1(display_short)|uniprotkb:Kiaa0440(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-8334367(isoform-parent)|ensembl:ENSMUSG00000042700(gene)|ensembl:ENSMUST00000222298(transcript) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:rKZAc8eQTL+l1kbvtX79UARkGUY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q5SVG5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16735551|ensembl:ENSMUSP00000105523 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q5svg5_mouse(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000009090(gene)|ensembl:ENSMUST00000109897(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|interpro:IPR032682 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:ax1zFnM+xtWV5UbOgb99OBzZSGI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8K4P8-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118023 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q8k4p8-2(display_long)|uniprotkb:Hecw1(gene name)|psi-mi:Hecw1(display_short)|uniprotkb:Kiaa0322(gene name synonym)|uniprotkb:Nedl1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q8K4P8-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:eX90uao1wjmUc7I0lFYstlaFD1M10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P39688 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-524514|uniprotkb:Q3TAT3|uniprotkb:Q3U0T5|uniprotkb:Q8K2A3|ensembl:ENSMUSP00000097547 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:fyn_mouse(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Fyn(gene name)|psi-mi:Fyn(display_short)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000019843(gene)|ensembl:ENSMUST00000099967(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001764"(neuron migration)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003015"(heart process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042552"(myelination)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0015631"(tubulin binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0014069"(postsynaptic density)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR036028|mint:P39688|rcsb pdb:3UF4|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1227986|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202733|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-373753|reactome:R-MMU-375165|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-5621480|reactome:R-MMU-5621575|reactome:R-MMU-5673001|reactome:R-MMU-6811558|reactome:R-MMU-75892|reactome:R-MMU-8866376|reactome:R-MMU-9032759|reactome:R-MMU-912631|refseq:NP_001116364.1|refseq:NP_001116365.1|refseq:NP_032080.2|refseq:XP_006512602.1|refseq:XP_006512603.1|refseq:XP_011241419.1|dip:DIP-198N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:QVU98HrNOdxdJIzSvFWdhZ914MQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q030 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27118008|ensembl:ENSMUSP00000127818 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q030_mouse(display_long)|uniprotkb:Ablim1(gene name)|psi-mi:Ablim1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001096648.1|ensembl:ENSMUSG00000025085(gene)|ensembl:ENSMUST00000104902(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:/POfyKGIExsP8kBN/rwYYXrflMQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8CIQ7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-2112210 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:dock3_mouse(display_long)|uniprotkb:Dock3(gene name)|psi-mi:Dock3(display_short)|uniprotkb:Moca(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR027357|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|interpro:IPR043161|interpro:IPR043162|interpro:IPR032376|interpro:IPR027007|interpro:IPR026800|interpro:IPR026791|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|interpro:IPR035892|interpro:IPR037811|interpro:IPR035767|interpro:IPR036028|reactome:R-MMU-9032759|reactome:R-MMU-983231|interpro:IPR042455|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Y4Ja4mtQBITd7KP0b5Q+y1L/cME10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:F8VPU2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16725343|ensembl:ENSMUSP00000026635|uniprotkb:C4IXU2 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:farp1_mouse(display_long)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym)|uniprotkb:Farp1(gene name)|psi-mi:Farp1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000025555(gene)|ensembl:ENSMUST00000026635(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9035034|refseq:NP_598843.3|refseq:XP_006518977.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:FF1E2m+C2jrf4rDejtDV2rn93GA10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q0K9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117997|ensembl:ENSMUSP00000129082 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q0k9_mouse(display_long)|uniprotkb:Elmod1(gene name)|psi-mi:Elmod1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000041986(gene)|ensembl:ENSMUST00000166580(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR030722 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:1GA0vq1ozYUNAJad3WcPOFVGQ5010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UU96-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117990 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q3uu96-2(display_long)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Kiaa0451(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q3UU96-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Yi85TSrSomQZttBguKNuXlarRpo10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61753 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-1633989|uniprotkb:Q3TEE5|uniprotkb:Q75SV9|uniprotkb:Q8C603|ensembl:ENSMUSP00000064755 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:sera_mouse(display_long)|uniprotkb:Phgdh(gene name)|psi-mi:Phgdh(display_short)|uniprotkb:A10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_058662.2|ensembl:ENSMUSG00000053398(gene)|ensembl:ENSMUST00000065793(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031175"(neuron projection development)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:Q61753|reactome:R-MMU-977347 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:66i2iIx5qSIN6BkqSPF14+UqDIA10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P62137 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-357187|ensembl:ENSMUSP00000039109|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:Q3U7G7|uniprotkb:Q9Z1G2 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pp1a_mouse(display_long)|uniprotkb:Ppp1ca(gene name)|psi-mi:Ppp1ca(display_short)|uniprotkb:Ppp1a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009987"(cellular process)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62137|rcsb pdb:5ZQV|rcsb pdb:5ZT0|reactome:R-MMU-180024|ensembl:ENSMUSG00000040385(gene)|ensembl:ENSMUST00000046094(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|refseq:NP_114074.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:kr38FkfqhN5ex5rxh4ZJbSdd8IM10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61553 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-2308857|uniprotkb:O09099|uniprotkb:O09156|uniprotkb:Q05DK3|uniprotkb:Q7TN32|uniprotkb:Q80V75|ensembl:ENSMUSP00000031565 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:fscn1_mouse(display_long)|uniprotkb:Fscn1(gene name)|psi-mi:Fscn1(display_short)|uniprotkb:Fan1(gene name synonym)|uniprotkb:Snl(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032010.2|dip:DIP-54657N|ensembl:ENSMUSG00000029581(gene)|ensembl:ENSMUST00000031565(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044393"(microspike)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q61553 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:D+qdiRYJCXobCuZmdebrhb32jSI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9QYR6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-774021|uniprotkb:A2ARN9|uniprotkb:Q3TQM8|uniprotkb:Q3TUV8|uniprotkb:Q3UHB7|uniprotkb:Q9QZH9|uniprotkb:Q9QZI0|uniprotkb:Q9QZI1|ensembl:ENSMUSP00000106269 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:map1a_mouse(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1(gene name synonym)|uniprotkb:Mtap1a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001166977.1|refseq:NP_115769.1|ensembl:ENSMUSG00000027254(gene)|ensembl:ENSMUST00000110639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|mint:Q9QYR6|rcsb pdb:5GNV - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:YFVfrv4h8ioQ9vL1A9LYsA5xriQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61301-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117541|ensembl:ENSMUSP00000074809 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q61301-2(display_long)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)|uniprotkb:Catna2(gene name synonym)|uniprotkb:alpha N-catenin I(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-774089(isoform-parent)|ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000075340(transcript) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:9aQcqCFRuTb8VINT4AAWYzztx9w10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9QA63 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117503|ensembl:ENSMUSP00000081324 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9qa63_mouse(display_long)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000028649(gene)|ensembl:ENSMUST00000084301(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0042995"(cell projection)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041615|interpro:IPR043197|interpro:IPR041573 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:61SHkkaTH2fhG/KYeQ0ZvSaSTF810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9QXS1-15 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117493 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q9qxs1-15(display_long)|uniprotkb:Plectin-1(gene name synonym)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-774583(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:kfZ8kQX7no2IHB2MQHH0LChXxa010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9JIS5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-911297|uniprotkb:Q80TT0|uniprotkb:Q8R0R5|ensembl:ENSMUSP00000037576 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:sv2a_mouse(display_long)|uniprotkb:Calcium regulator SV2A(gene name synonym)|uniprotkb:Sv2a(gene name)|psi-mi:Sv2a(display_short)|uniprotkb:Kiaa0736(gene name synonym)|uniprotkb:Sv2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_071313.1|ensembl:ENSMUSG00000038486(gene)|ensembl:ENSMUST00000035371(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014052"(regulation of gamma-aminobutyric acid secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|mint:Q9JIS5 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:bIEjg35nYkj/s0a7BvwB8Q8gbbk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9DC53 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-2013366|uniprotkb:Q9CUZ8|uniprotkb:B2RS65|ensembl:ENSMUSP00000067774 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cpne8_mouse(display_long)|uniprotkb:Cpne8(gene name)|psi-mi:Cpne8(display_short)|uniprotkb:Copine VIII(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_080091.1|ensembl:ENSMUSG00000052560(gene)|ensembl:ENSMUST00000064391(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|reactome:R-MMU-9013148|reactome:R-MMU-9013405|reactome:R-MMU-9013406 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:7J+kZzV7BylBYYuusvUdt4eJPxE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61699-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117982|ensembl:ENSMUSP00000074392 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q61699-2(display_long)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000074846(transcript)|intact:EBI-772450(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:f+G0HlyMoB70OgKWPbOLbwTAQq410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P97798-5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117975 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:p97798-5(display_long)|uniprotkb:Neo1(gene name)|psi-mi:Neo1(display_short)|uniprotkb:Ngn(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:P97798-5(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:JlG73jEpoQ/uLHPlWtfIkifVlFw10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q8I9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16732044|ensembl:ENSMUSP00000084454|uniprotkb:Q4VA57|uniprotkb:Q5DTL4|uniprotkb:Q8BIW6|uniprotkb:Q8BUA0|uniprotkb:Q8CG91 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:fry_mouse(display_long)|uniprotkb:Fry(gene name)|psi-mi:Fry(display_short)|uniprotkb:Kiaa4143(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000056602(gene)|ensembl:ENSMUST00000087204(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005938"(cell cortex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031175"(neuron projection development)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025481|interpro:IPR025614|interpro:IPR029473|interpro:IPR039867|mint:E9Q8I9|refseq:NP_766475.2|refseq:XP_006504993.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:fvduzhqkwcM9qmnWvPWAA1W8HqI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P68040 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P59281-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16735577|ensembl:ENSMUSP00000158984 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:p59281-2(display_long)|uniprotkb:Arhgap39(gene name)|psi-mi:Arhgap39(display_short)|uniprotkb:D15Wsu169e(gene name synonym)|uniprotkb:Kiaa1688(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-772284(isoform-parent)|ensembl:ENSMUSG00000033697(gene)|ensembl:ENSMUST00000239134(transcript) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:xxFSkacr9YHzYICJc/WOPs3s7Zk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:H3BLF7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-26472753|ensembl:ENSMUSP00000135769 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:h3blf7_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000176411(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR036322|mint:H3BLF7 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:/51pnfRbvLuDkt4x6WTJwTQLBCI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:B1AWN6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27101130|ensembl:ENSMUSP00000028377|ensembl:ENSMUSP00000097645|uniprotkb:A0A0J9YTW6 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:scn2a_mouse(display_long)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.2(gene name synonym)|uniprotkb:Scn2a(gene name)|psi-mi:Scn2a(display_short)|uniprotkb:Scn2a1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000075318(gene)|ensembl:ENSMUST00000028377(transcript)|ensembl:ENSMUST00000100067(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007399"(nervous system development)|go:"GO:0007613"(memory)|go:"GO:0008627"(intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034706"(sodium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043194"(axon initial segment)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099508"(voltage-gated ion channel activity involved in regulation of presynaptic membrane potential)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|refseq:NP_001092768.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:MDShbnlkaUAzrOt/jVBSBso7wK010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80U28-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117968 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q80u28-3(display_long)|uniprotkb:Madd(gene name)|psi-mi:Madd(display_short)|uniprotkb:Kiaa0358(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q80U28-3(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:fkELe7w/gTsKaYWN04qtEkQKf7M10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8BX70-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117959 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q8bx70-2(display_long)|uniprotkb:Vps13c(gene name)|psi-mi:Vps13c(display_short)|uniprotkb:Kiaa3021(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q8BX70-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:EcLNYYQbSO8pTv94r22meUXxvx410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P63328 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-397208|uniprotkb:P12816|uniprotkb:P20652|uniprotkb:Q3UCU1|uniprotkb:Q64135|ensembl:ENSMUSP00000053101 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pp2ba_mouse(display_long)|uniprotkb:Ppp3ca(gene name)|psi-mi:Ppp3ca(display_short)|uniprotkb:Calna(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032939.1|refseq:NP_001280551.1|ensembl:ENSMUSG00000028161(gene)|ensembl:ENSMUST00000056758(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042383"(sarcolemma)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P63328|rcsb pdb:4ORB|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|dip:DIP-31543N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:98yAyDGZZxKYOv22ejceyfJbvao10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P49025-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16736749 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:p49025-3(display_long)|uniprotkb:Rho-interacting, serine/threonine-protein kinase 21(gene name synonym)|uniprotkb:Citron(isoform synonym)|uniprotkb:Cit(gene name)|psi-mi:Cit(display_short)|uniprotkb:Crik(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-397301(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:LsDrbX4GwS3kSPuSp0J1NOwrQfU10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P11881-8 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117948 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:p11881-8(display_long)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)|uniprotkb:SI-SII(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:P11881-8(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:iYNeP6n3KzoUFCkJ2HFtDZB1ff010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8R0S2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-772277|uniprotkb:Q3TZC3|uniprotkb:Q5DU15|ensembl:ENSMUSP00000098712 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:iqec1_mouse(display_long)|uniprotkb:Iqsec1(gene name)|psi-mi:Iqsec1(display_short)|uniprotkb:Kiaa0763(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001127855.1|ensembl:ENSMUSG00000034312(gene)|ensembl:ENSMUST00000101153(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR030737|interpro:IPR033742|interpro:IPR035999 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:BZg7CaLndE4ak8KXs34YFf9iBRQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:O88343-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117939 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:o88343-2(display_long)|uniprotkb:Slc4a4(gene name)|psi-mi:Slc4a4(display_short)|uniprotkb:Nbc1(gene name synonym)|uniprotkb:Nbce1(gene name synonym)|uniprotkb:kNBC(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:O88343-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:a2q/PI1yKqH8DqQVoCrqlzbCq6E10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q4VA93 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-911551|ensembl:ENSMUSP00000062392 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q4va93_mouse(display_long)|uniprotkb:Prkca(gene name)|psi-mi:Prkca(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000050965(gene)|ensembl:ENSMUST00000059595(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002159"(desmosome assembly)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_035231.2|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034663|interpro:IPR035892|rcsb pdb:6UWA - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Y3paSSKWHeZcmEXDHpDFBuvsbYA10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8JZZ7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27100346|ensembl:ENSMUSP00000101734|uniprotkb:E9Q6C7|uniprotkb:Q8BM90 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:agrl2_mouse(display_long)|uniprotkb:Adgrl2(gene name)|psi-mi:Adgrl2(display_short)|uniprotkb:Kiaa0786(gene name synonym)|uniprotkb:Lphn2(gene name synonym)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000028184(gene)|ensembl:ENSMUST00000106128(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0043005"(neuron projection)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031240|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159|rcsb pdb:6SKE - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:U64jL9NHd9blq0nFGzRjbeXYyjU10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:O54774 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-775247|ensembl:ENSMUSP00000020420 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ap3d1_mouse(display_long)|uniprotkb:AP-3 complex subunit delta(gene name synonym)|uniprotkb:Delta-adaptin(gene name synonym)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:Ap3d(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit delta-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_031486.1|dip:DIP-32163N|ensembl:ENSMUSG00000020198(gene)|ensembl:ENSMUST00000020420(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:O54774 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:q83u6ORB4zYNuQihE4PI1rhvSkY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:J3QP81 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117918|ensembl:ENSMUSP00000137137 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:j3qp81_mouse(display_long)|uniprotkb:Clasp1(gene name)|psi-mi:Clasp1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000064302(gene)|ensembl:ENSMUST00000178710(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:kU1NQBzsJGDikT1EJD8PFX9pWp810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q5E1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117899|ensembl:ENSMUSP00000128313 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q5e1_mouse(display_long)|uniprotkb:Pcdh19(gene name)|psi-mi:Pcdh19(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001098716.1|go:"GO:0007420"(brain development)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030716|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|ensembl:ENSMUSG00000051323(gene)|ensembl:ENSMUST00000167944(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:WfhMIDCpZDywBRII/mjd1NGNK+U10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q06890 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-774758|ensembl:ENSMUSP00000022616 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:clus_mouse(display_long)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:Clustrin(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Clu(gene name)|psi-mi:Clu(display_short)|uniprotkb:Apoj(gene name synonym)|uniprotkb:Msgp-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_038520.2|refseq:XP_006518567.1|ensembl:ENSMUSG00000022037(gene)|ensembl:ENSMUST00000022616(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0017038"(protein import)|go:"GO:0030426"(growth cone)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0071944"(cell periphery)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:Q06890|reactome:R-MMU-114608|reactome:R-MMU-166665|reactome:R-MMU-6803157|reactome:R-MMU-977606|go:"GO:0042583"(chromaffin granule) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wP6AESslzICF3ojv9a+vJUn61VA10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:O70443 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771994|uniprotkb:O70442|uniprotkb:Q61637|uniprotkb:Q91WM4|ensembl:ENSMUSP00000036087|ensembl:ENSMUSP00000124639 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:gnaz_mouse(display_long)|uniprotkb:"G(x) alpha chain"(gene name synonym)|uniprotkb:Gz-alpha(gene name synonym)|uniprotkb:Gnaz(gene name)|psi-mi:Gnaz(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_034441.1|refseq:XP_006513299.1|refseq:XP_006513300.1|refseq:XP_006513298.1|ensembl:ENSMUSG00000040009(gene)|ensembl:ENSMUST00000037813(transcript)|ensembl:ENSMUST00000159991(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:O70443|reactome:R-MMU-418597 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:tIlKib9CoNSvCkb2TvLU/QwdCYk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:F7ADT6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117889|ensembl:ENSMUSP00000108725 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:f7adt6_mouse(display_long)|uniprotkb:Gapvd1(gene name)|psi-mi:Gapvd1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000026867(gene)|ensembl:ENSMUST00000113101(transcript)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:hT28Oy3kOWo1e98lrrZ20BHcxmc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9Z0H8-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117881 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q9z0h8-2(display_long)|uniprotkb:Clip2(gene name)|psi-mi:Clip2(display_short)|uniprotkb:Cyln2(gene name synonym)|uniprotkb:Kiaa0291(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q9Z0H8-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:RYrRUC5RHWBLkl5LIJ42v/7HDn010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2AG41 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117870|ensembl:ENSMUSP00000118465 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a2ag41_mouse(display_long)|uniprotkb:Stoml2(gene name)|psi-mi:Stoml2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000028455(gene)|ensembl:ENSMUST00000138030(transcript)|go:"GO:0016020"(membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR036013 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:aPZy7FBpM6fhtq2R3ZSqKgmADq010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9WU60 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117827|uniprotkb:A2AP43|uniprotkb:Q9R263|uniprotkb:Q9WU77|ensembl:ENSMUSP00000028781 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:atrn_mouse(display_long)|uniprotkb:Protein mahogany(gene name synonym)|uniprotkb:Atrn(gene name)|psi-mi:Atrn(display_short)|uniprotkb:Mg(gene name synonym)|uniprotkb:Mgca(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_033860.2|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042552"(myelination)|go:"GO:0043473"(pigmentation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001304(C-type lectin)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002165(Plexin)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR016201(Plexin-like fold)|go:"GO:0009888"(tissue development)|interpro:IPR035914|ensembl:ENSMUSG00000027312(gene)|ensembl:ENSMUST00000028781(transcript)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009887"(animal organ morphogenesis) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:3bcN2vNIzanHmUES2YYVKJaIRrs10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q0I8 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117820|ensembl:ENSMUSP00000105123 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q0i8_mouse(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000007617(gene)|ensembl:ENSMUST00000109497(transcript) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:7LJqkgS2l+gXU/yeJj4d/rVaCJI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9WTS5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16734841|uniprotkb:Q5NBW7|uniprotkb:Q5NBW8|uniprotkb:Q80TJ0|uniprotkb:Q9JLC0|uniprotkb:Q9QYZ1 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ten2_mouse(display_long)|uniprotkb:Protein Odd Oz/ten-m homolog 2(gene name synonym)|uniprotkb:Tenascin-M2(gene name synonym)|uniprotkb:Teneurin transmembrane protein 2(gene name synonym)|uniprotkb:Tenm2(gene name)|psi-mi:Tenm2(display_short)|uniprotkb:Kiaa1127(gene name synonym)|uniprotkb:Odz2(gene name synonym)|uniprotkb:Tnm2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0016605"(PML body)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR022385|interpro:IPR027689|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR028916|interpro:IPR006530(YD repeat) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:wQ0xOO0bqzQ0E++dsnlaGkXJyis10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9Z1B3-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117812|ensembl:ENSMUSP00000064844|ensembl:ENSMUSP00000118756 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q9z1b3-2(display_long)|uniprotkb:Phosphoinositide phospholipase C-beta-1(gene name synonym)|uniprotkb:PLC-154(gene name synonym)|uniprotkb:Phospholipase C-beta-1(gene name synonym)|uniprotkb:Plcb1(gene name)|psi-mi:Plcb1(display_short)|uniprotkb:Plcb(gene name synonym)|uniprotkb:C-beta-1b(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000051177(gene)|ensembl:ENSMUST00000070724(transcript)|ensembl:ENSMUST00000131552(transcript)|intact:EBI-397636(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:sh19QbAiv4gIpNNvexb7kChd8ys10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P16054 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P63101 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:F6U8U1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117799|ensembl:ENSMUSP00000115985 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:f6u8u1_mouse(display_long)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000022957(gene)|ensembl:ENSMUST00000125052(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035892|interpro:IPR035899 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:7DJbwyIkMfs5hnyWMJFxD0+ewFE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9R0N3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-647443|uniprotkb:Q7TQG8|ensembl:ENSMUSP00000088464|ensembl:ENSMUSP00000103129 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:syt11_mouse(display_long)|uniprotkb:Synaptotagmin XI(gene name synonym)|uniprotkb:Syt11(gene name)|psi-mi:Syt11(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_061274.2|refseq:XP_006501411.1|ensembl:ENSMUSG00000068923(gene)|ensembl:ENSMUST00000090945(transcript)|ensembl:ENSMUST00000107505(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0009611"(response to wounding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1900243"(negative regulation of synaptic vesicle endocytosis)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905154"(negative regulation of membrane invagination)|go:"GO:1905162"(regulation of phagosome maturation)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|go:"GO:1905469"(negative regulation of clathrin-coated pit assembly)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028699|interpro:IPR035892|mint:Q9R0N3|reactome:R-MMU-8856825|reactome:R-MMU-8856828 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:hmxn6TCXurR8053TJ6OB1+IMiJ410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q69ZH9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-26472113|uniprotkb:Q8BNY7|uniprotkb:Q9JJD6 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:rhg23_mouse(display_long)|uniprotkb:Arhgap23(gene name)|psi-mi:Arhgap23(display_short)|uniprotkb:Kiaa1501(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 23(gene name synonym)|uniprotkb:MNCb-1301(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|reactome:R-MMU-8980692|reactome:R-MMU-9013149|mint:Q69ZH9|refseq:NP_067468.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR041489|interpro:IPR036034|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR041681|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:KTCeDuLV+qHtInBwC3PzUFi0VO810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q04690-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16735896|ensembl:ENSMUSP00000103886 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q04690-2(display_long)|uniprotkb:Neurofibromatosis-related protein NF-1(gene name synonym)|uniprotkb:Nf1(gene name)|psi-mi:Nf1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000020716(gene)|ensembl:ENSMUST00000108251(transcript)|intact:EBI-397326(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:fuDOIDn4zUo2i8/UjdAQZessAyc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2A8L5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771868|uniprotkb:Q6PG86|uniprotkb:Q9EQ17|ensembl:ENSMUSP00000039368 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ptprf_mouse(display_long)|uniprotkb:Ptprf(gene name)|psi-mi:Ptprf(display_short)|uniprotkb:Lar(gene name synonym)|uniprotkb:Leukocyte common antigen related(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_035343.2|ensembl:ENSMUSG00000033295(gene)|ensembl:ENSMUST00000049074(transcript)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035373"(chondroitin sulfate proteoglycan binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060076"(excitatory synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900121"(negative regulation of receptor binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:3PXH|rcsb pdb:6X39|reactome:R-MMU-388844|reactome:R-MMU-8849932 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:+BPaDKLeYgJ+Yz6UKakFSmlXPxg10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q91V14-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117790 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q91v14-2(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Kiaa1176(gene name synonym)|uniprotkb:KCC2b(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q91V14-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:A41Evd0ggNpw32R3e6/sAPCI2N810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q5F6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-13953952|ensembl:ENSMUSP00000104347 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q5f6_mouse(display_long)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000008348(gene)|ensembl:ENSMUST00000108707(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:h8AGghFIavBEikpHCCtiCIA1NJM10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P49615 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6510052|ensembl:ENSMUSP00000030814 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cdk5_mouse(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:Cdkn5(gene name synonym)|uniprotkb:Crk6(gene name synonym)|uniprotkb:CR6 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000028969(gene)|ensembl:ENSMUST00000030814(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099533"(positive regulation of presynaptic cytosolic calcium concentration)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49615|reactome:R-MMU-180024|reactome:R-MMU-399956|reactome:R-MMU-6804756|refseq:NP_031694.1|dip:DIP-29353N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:mFzCd7zhLyXpxPDQwc1xXCraDQI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:B8QI36 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6271767|ensembl:ENSMUSP00000128314 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:b8qi36_mouse(display_long)|uniprotkb:Ppfia4(gene name)|psi-mi:Ppfia4(display_short)|uniprotkb:ppfia4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000026458(gene)|ensembl:ENSMUST00000168515(transcript)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030439|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-388844|refseq:NP_001138327.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Fj3ZFm3zkJLsJ93fkkirRbUnjl810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9JIA1 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-445256|ensembl:ENSMUSP00000143128 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:lgi1_mouse(display_long)|uniprotkb:Lgi1(gene name)|psi-mi:Lgi1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_064674.1|ensembl:ENSMUSG00000067242(gene)|ensembl:ENSMUST00000198518(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007411"(axon guidance)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031175"(neuron projection development)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005492(EPTP)|interpro:IPR009039(EAR)|interpro:IPR032675|mint:Q9JIA1|reactome:R-MMU-5682910 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:PEM1comV+IMxsMdEb0dRsl2+pqg10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q80U49 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16728053|ensembl:ENSMUSP00000098580|ensembl:ENSMUSP00000137331|ensembl:ENSMUSP00000152451|uniprotkb:Q3UH33|uniprotkb:Q3UHG1|uniprotkb:Q80UM2 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:c170b_mouse(display_long)|uniprotkb:Centrosomal protein 170B(gene name synonym)|uniprotkb:Cep170b(gene name)|psi-mi:Cep170b(display_short)|uniprotkb:Kiaa0284(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000072825(gene)|ensembl:ENSMUST00000101018(transcript)|ensembl:ENSMUST00000179041(transcript)|ensembl:ENSMUST00000222711(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029300|refseq:NP_001019773.2|refseq:XP_006515829.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:vmI/x564L8rTcob6vkmQLu2+JCQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P18052 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6ZPE2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771895|uniprotkb:Q4QQM2|uniprotkb:Q8BK68|uniprotkb:Q8K2Z0|uniprotkb:B2RXQ1|uniprotkb:B2RXX4|uniprotkb:B7ZWK2|ensembl:ENSMUSP00000120725 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:mtmr5_mouse(display_long)|uniprotkb:SET-binding factor 1(gene name synonym)|uniprotkb:Sbf1(gene name)|psi-mi:Sbf1(display_short)|uniprotkb:Kiaa3020(gene name synonym)|uniprotkb:Mtmr5(gene name synonym)|uniprotkb:Inactive phosphatidylinositol 3-phosphatase 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001074499.2|refseq:NP_001164032.1|ensembl:ENSMUSG00000036529(gene)|ensembl:ENSMUST00000123791(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001691"(pseudophosphatase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0016604"(nuclear body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001194(DENN)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR004182(GRAM)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022096|interpro:IPR029021|interpro:IPR030564|interpro:IPR030574|interpro:IPR037516|interpro:IPR043153|rcsb pdb:1V5U|reactome:R-MMU-1483248|reactome:R-MMU-8876198 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:EXetiIj59Q3tqiAmw422ux9X6NY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3TWV4 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117769|ensembl:ENSMUSP00000087477 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q3twv4_mouse(display_long)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001289899.1|ensembl:ENSMUSG00000022841(gene)|ensembl:ENSMUST00000090023(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0030131"(clathrin adaptor complex)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:zq5vvE0JV87QlpnLDuNVcxK6tNQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q175 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117737|ensembl:ENSMUSP00000108891 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q175_mouse(display_long)|uniprotkb:Unconventional myosin-VI(gene name synonym)|uniprotkb:Myo6(gene name)|psi-mi:Myo6(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:XP_006510901.1|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015031"(protein transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|ensembl:ENSMUST00000113266(transcript)|ensembl:ENSMUSG00000033577(gene) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:0P28+cYx88ZXhFJc0MoJPXiFp8k10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P70206 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771260|uniprotkb:Q5DTR0|uniprotkb:B2RQP7|ensembl:ENSMUSP00000063066|ensembl:ENSMUSP00000131840 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:plxa1_mouse(display_long)|uniprotkb:Plxna1(gene name)|psi-mi:Plxna1(display_short)|uniprotkb:Kiaa4053(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_032907.1|dip:DIP-29745N|go:"GO:0016020"(membrane)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0097485"(neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1990138"(neuron projection extension)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|interpro:IPR042744|mint:P70206|rcsb pdb:3RYT|rcsb pdb:5L56|rcsb pdb:5L59|rcsb pdb:5L5C|rcsb pdb:5L7N|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|reactome:R-MMU-416700|reactome:R-MMU-9696273|ensembl:ENSMUSG00000030084(gene)|ensembl:ENSMUST00000049845(transcript)|ensembl:ENSMUST00000163139(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014910"(regulation of smooth muscle cell migration) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:AgCACazq+fYBgTGYIAKk2hRbPEw10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q91ZX7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-300955|uniprotkb:Q61291|uniprotkb:Q920Y4 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:lrp1_mouse(display_long)|uniprotkb:Lrp1(gene name)|psi-mi:Lrp1(display_short)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:A2mr(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) mint:Q91ZX7|go:"GO:0002020"(protease binding)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016964"(alpha-2 macroglobulin receptor activity)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032370"(positive regulation of lipid transport)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904300"(positive regulation of transcytosis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|reactome:R-MMU-2168880|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048694"(positive regulation of collateral sprouting of injured axon)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0045807"(positive regulation of endocytosis)|reactome:R-MMU-975634|refseq:NP_032538.2|dip:DIP-47785N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:lX7IFHEMgDZnvC069QGK9D4BL1Y10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q0KL02-3 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16736247 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q0kl02-3(display_long)|uniprotkb:Trio(gene name)|psi-mi:Trio(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-16725543(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:qbxBZT0BUNqZOG52EvFv7I4bxGw10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:H3BJU7 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-26888274|ensembl:ENSMUSP00000135131 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:h3bju7_mouse(display_long)|uniprotkb:Rho guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000177303(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0051301"(cell division)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:RLLGJiIxCak7aSxkAzC1eS2eshI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q3L2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-773641|uniprotkb:Q3UVT5|uniprotkb:Q6DIC7|uniprotkb:Q7TNG2|uniprotkb:Q80Y45 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pi4ka_mouse(display_long)|uniprotkb:Pik4(gene name synonym)|uniprotkb:Pik4ca(gene name synonym)|uniprotkb:Pi4ka(gene name)|psi-mi:Pi4ka(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001001983.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR042236|refseq:XP_006522097.1|interpro:IPR036940|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0046786"(viral replication complex formation and maintenance)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|reactome:R-MMU-1483248|reactome:R-MMU-1660514|mint:E9Q3L2 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:IndUgD7njY39mo58MVLNKGSeD4c10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2AI78 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117718|ensembl:ENSMUSP00000108132 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a2ai78_mouse(display_long)|uniprotkb:Cnksr2(gene name)|psi-mi:Cnksr2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:XP_011246128.1|ensembl:ENSMUSG00000025658(gene)|ensembl:ENSMUST00000112513(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:k0G/4R4ac9DV3bWJwxX4TbCqZh810090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P61982 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q9QXS6-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117712 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q9qxs6-2(display_long)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short)|uniprotkb:Drba(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q9QXS6-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:LMFbr2+DSIvjOJqJeq8mPFNHGiU10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q4FE56 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117682|ensembl:ENSMUSP00000086716 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q4fe56_mouse(display_long)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_033507.2|refseq:XP_011245759.1|ensembl:ENSMUSG00000031010(gene)|ensembl:ENSMUST00000089302(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:M9hsX76KLD0jeDoBG/w6KIOZUv410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q91Y20 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117664|ensembl:ENSMUSP00000111322 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pcdaa_mouse(display_long)|uniprotkb:Pcdha10(gene name)|psi-mi:Pcdha10(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_034091.1|ensembl:ENSMUSG00000007440(gene)|ensembl:ENSMUST00000115658(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR031904 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:dJ5gemx5ucIT7RheaBEsDKWtB4s10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6R891 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-774681|uniprotkb:Q8K0X7|ensembl:ENSMUSP00000041732 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:neb2_mouse(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:Ppp1r9b(gene name)|psi-mi:Ppp1r9b(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_758465.2|ensembl:ENSMUSG00000038976(gene)|ensembl:ENSMUST00000038696(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q6R891 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:UKGG1FQWWvX56wsI2kQB1jU5uOc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:O35098 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-773225|uniprotkb:O08886|uniprotkb:Q3UL94 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:dpyl4_mouse(display_long)|uniprotkb:Collapsin response mediator protein 3(gene name synonym)|uniprotkb:UNC33-like phosphoprotein 4(gene name synonym)|uniprotkb:Dpysl4(gene name)|psi-mi:Dpysl4(display_short)|uniprotkb:Crmp3(gene name synonym)|uniprotkb:Ulip4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR030612|interpro:IPR032466|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011778(D-hydantoinase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|mint:O35098|go:"GO:0005737"(cytoplasm)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0031005"(filamin binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070997"(neuron death)|go:"GO:0097485"(neuron projection guidance)|reactome:R-MMU-399956 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:OUbDfG6PnA7vEdKa4RKXK2cprCk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q4ACU6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:D3YZU5 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16737529|ensembl:ENSMUSP00000103567 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:d3yzu5_mouse(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000038738(gene)|ensembl:ENSMUST00000107934(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|refseq:XP_006540929.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:krLJHujObgducGteePyU78Ab/SI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9QK16 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117640|ensembl:ENSMUSP00000080808 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9qk16_mouse(display_long)|uniprotkb:Fat3(gene name)|psi-mi:Fat3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001074283.1|ensembl:ENSMUSG00000074505(gene)|ensembl:ENSMUST00000082170(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:y+MhGaBVTPhIyaOnsnL+W5irbq410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9Q6A9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117626|ensembl:ENSMUSP00000125763 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9q6a9_mouse(display_long)|uniprotkb:Ctnnb1(gene name)|psi-mi:Ctnnb1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000006932(gene)|ensembl:ENSMUST00000154356(transcript)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0045296"(cadherin binding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:VHMLY2AjfwCpAw5md140XXqlFKQ10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6PHZ2-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16736701|ensembl:ENSMUSP00000102008 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q6phz2-2(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)|uniprotkb:Delta 6(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-2308458(isoform-parent)|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000106400(transcript) - - isoform-comment:"Ref.1 (BAE25062) sequence is in conflict in position: 478:N->K." figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:K4WFjBG9XZekthJR/1BHwRR4Vh410090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2ANL9 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117607|ensembl:ENSMUSP00000110710 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:a2anl9_mouse(display_long)|uniprotkb:Tenm1(gene name)|psi-mi:Tenm1(display_short)|uniprotkb:Odz1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:XP_006541555.1|ensembl:ENSMUSG00000016150(gene)|ensembl:ENSMUST00000115058(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR006530(YD repeat)|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR028916 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:tZ6aP4XpP4cM2zhO/c37mm5ujm010090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:G5E8K5-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117601|ensembl:ENSMUSP00000138347 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:g5e8k5-2(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000069601(gene)|ensembl:ENSMUST00000182155(transcript)|intact:EBI-457262(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:Cu1VTqQRo2HHAVuSfJ4eTMw/gbk10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q3UHK6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-773013|uniprotkb:O70465|uniprotkb:Q3TSI0|uniprotkb:Q3UH52|uniprotkb:Q80TF5|uniprotkb:Q9WTS7 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ten4_mouse(display_long)|uniprotkb:Tenm4(gene name)|psi-mi:Tenm4(display_short)|uniprotkb:Doc4(gene name synonym)|uniprotkb:Downstream of CHOP4(gene name synonym)|uniprotkb:Kiaa1302(gene name synonym)|uniprotkb:Odz4(gene name synonym)|uniprotkb:Protein Odd Oz/ten-m homolog 4(gene name synonym)|uniprotkb:Tenascin-M4(gene name synonym)|uniprotkb:Teneurin transmembrane protein 4(gene name synonym)|uniprotkb:Tnm4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR031325|refseq:NP_001297689.1|refseq:NP_001297691.1|refseq:NP_035988.2|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR013111(EGF, extracellular)|interpro:IPR022385|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR006530(YD repeat)|interpro:IPR028916|refseq:XP_017177717.1|interpro:IPR027691|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060912"(cardiac cell fate specification)|go:"GO:2000543"(positive regulation of gastrulation)|mint:Q3UHK6 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:0oVMre4l1F1JwL4Gu0Uz8P2bDew10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q61137-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-21979018|ensembl:ENSMUSP00000039711 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q61137-2(display_long)|uniprotkb:Neuronal migration protein GC14(gene name synonym)|uniprotkb:Astn1(gene name)|psi-mi:Astn1(display_short)|uniprotkb:Astn(gene name synonym)|uniprotkb:Kiaa0289(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) intact:EBI-774766(isoform-parent)|ensembl:ENSMUSG00000026587(gene)|ensembl:ENSMUST00000046110(transcript) - - isoform-comment:No experimental confirmation available. figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:9b88Z+b4Kd47RHG1/ugse2BD+ag10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:F8VQE2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-11093601|ensembl:ENSMUSP00000074661 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:f8vqe2_mouse(display_long)|uniprotkb:Kif21b(gene name)|psi-mi:Kif21b(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001034561.1|ensembl:ENSMUSG00000041642(gene)|ensembl:ENSMUST00000075164(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:1990939"|interpro:IPR001680(WD40 repeat)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036322|interpro:IPR036961 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:astNEAnKFD7VDZP/PPuBM/bdDRY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q03137 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-1539152|uniprotkb:Q80VZ2|ensembl:ENSMUSP00000027451|ensembl:ENSMUSP00000139640|ensembl:ENSMUSP00000140954 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:epha4_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor SEK-1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor MPK-3(gene name synonym)|uniprotkb:Epha4(gene name)|psi-mi:Epha4(display_short)|uniprotkb:Sek(gene name synonym)|uniprotkb:Sek1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_031962.2|dip:DIP-1019N|ensembl:ENSMUST00000027451(transcript)|ensembl:ENSMUST00000188797(transcript)|ensembl:ENSMUST00000188952(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016301"(kinase activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048710"(regulation of astrocyte differentiation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097155"(fasciculation of sensory neuron axon)|go:"GO:0097156"(fasciculation of motor neuron axon)|go:"GO:0097161"(DH domain binding)|go:"GO:0097485"(neuron projection guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|ensembl:ENSMUSG00000026235(gene)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR030602|interpro:IPR034270|interpro:IPR036116|mint:Q03137|rcsb pdb:1B0X|rcsb pdb:2HEL|rcsb pdb:2I8J|rcsb pdb:2XYU|rcsb pdb:2Y6M|rcsb pdb:2Y6O|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:cDRUcRD/LB5owMEI7vdfcaD90uE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q8CH77-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117593 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q8ch77-2(display_long)|uniprotkb:Nav1(gene name)|psi-mi:Nav1(display_short)|uniprotkb:Kiaa1151(gene name synonym)|uniprotkb:Pomfil3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q8CH77-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:z0kWzgsxfTPR0nOc8aNiGn9yXkg10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P46660 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-400482|uniprotkb:Q61958|uniprotkb:Q8VCW5|ensembl:ENSMUSP00000041347 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ainx_mouse(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_666212.3|ensembl:ENSMUSG00000034336(gene)|ensembl:ENSMUST00000037636(transcript)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:P46660 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:amjP0AajB8s2oXmV96wzyfz6evE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P18760 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-1183994|ensembl:ENSMUSP00000147514 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:D3YZY0 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117582|ensembl:ENSMUSP00000120936 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:d3yzy0_mouse(display_long)|uniprotkb:Actg2(gene name)|psi-mi:Actg2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensembl:ENSMUST00000141904(transcript)|ensembl:ENSMUSG00000059430(gene) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:ZT8ux1n9shyblwCnwHPqm7dAhjc10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:A2A690 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16733043|ensembl:ENSMUSP00000097904|uniprotkb:A2A683|uniprotkb:Q3TRZ3|uniprotkb:Q5EBP6|uniprotkb:Q69ZQ7 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:tanc2_mouse(display_long)|uniprotkb:Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2(gene name synonym)|uniprotkb:Tanc2(gene name)|psi-mi:Tanc2(display_short)|uniprotkb:Kiaa1148(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000053580(gene)|ensembl:ENSMUST00000100330(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099519"(dense core granule cytoskeletal transport)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:A2A690|refseq:NP_851416.2 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:pr3yhn1QUhZm0o9/xXGd9g+QFoo10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q2NKI4 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117555|ensembl:ENSMUSP00000131351 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q2nki4_mouse(display_long)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)|uniprotkb:Prkcc(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001278363.1|ensembl:ENSMUST00000172109(transcript)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|ensembl:ENSMUSG00000078816(gene) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:fY69J5qyWnXM5SonVqqVtC6fP2M10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6URW6-2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-27117548 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:q6urw6-2(display_long)|uniprotkb:Myh14(gene name)|psi-mi:Myh14(display_short)|uniprotkb:NM II-C0(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) uniprotkb:Q6URW6-2(isoform-parent) - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:empqJCxis7t9kCzgT5oh2zwDBqI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:E9QMC2 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-16735783|ensembl:ENSMUSP00000102884|ensembl:ENSMUSP00000118393|uniprotkb:F6WSV0 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:e9qmc2_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000107263(transcript)|ensembl:ENSMUST00000125009(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|refseq:NP_001074883.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:j/j52EhyJy0J9a9bTS5JNjb3sbE10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:B2RQC6 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:P54763 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-537711|uniprotkb:Q9QVY4|uniprotkb:Q62213|uniprotkb:A3KG00|uniprotkb:A3KG01|uniprotkb:A3KG02|uniprotkb:A3KG89|uniprotkb:A3KG90|uniprotkb:Q6GTQ7|uniprotkb:Q6P5F1|ensembl:ENSMUSP00000101471 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:ephb2_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor EPH-3(gene name synonym)|uniprotkb:Neural kinase(gene name synonym)|uniprotkb:Nuk receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor SEK-3(gene name synonym)|uniprotkb:Ephb2(gene name)|psi-mi:Ephb2(display_short)|uniprotkb:Epth3(gene name synonym)|uniprotkb:Nuk(gene name synonym)|uniprotkb:Sek3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) refseq:NP_001277682.1|refseq:NP_034272.1|refseq:XP_006538594.1|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0001655"(urogenital system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016310"(phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042113"(B cell activation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0050878"(regulation of body fluid levels)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0005003"(ephrin receptor activity)|interpro:IPR011009(Protein kinase-like)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR011641(GCC2 and GCC3)|go:"GO:0106028"(neuron projection retraction)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|go:"GO:1904782"(negative regulation of NMDA glutamate receptor activity)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034238|interpro:IPR036116|mint:P54763|rcsb pdb:1JPA|rcsb pdb:1KGY|rcsb pdb:1NUK|interpro:IPR000719(Protein kinase, core)|rcsb pdb:1SHW|rcsb pdb:2HEN|rcsb pdb:3ETP|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|reactome:R-MMU-2682334|interpro:IPR003961(Fibronectin, type III)|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|ensembl:ENSMUSG00000028664(gene)|ensembl:ENSMUST00000105845(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001525"(angiogenesis)|dip:DIP-34917N - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:QgDJW2yhMS13Eb5l3DR03T814gI10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16056 uniprotkb:Q6ZQ58 intact:EBI-1798780|uniprotkb:Q62125 intact:EBI-6908968|ensembl:ENSMUSP00000136673|intact:EBI-9030511|uniprotkb:A2AFQ8|uniprotkb:J3QNB1|uniprotkb:Q7TSF7 psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:larp1_mouse(display_long)|uniprotkb:Larp1(gene name)|psi-mi:Larp1(display_short)|uniprotkb:Kiaa0731(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:Larp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27118288|imex:IM-29320-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) ensembl:ENSMUSG00000037331(gene)|ensembl:ENSMUST00000178636(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|refseq:NP_082727.1 - - - figure legend:ST10|comment:Co-IP/MS without HGF stimulation|comment:Protein MIA3 was not added because the Uniprot ID provided by author is obsolete.|comment:"There is inconsistency in the numbering of the tables between the file \"Appendix A. Supplementary material\" available in the Biological Psychiatry journal page (https://www.sciencedirect.com/science/article/pii/S0006322316001347?via%3Dihub) and the files available in PMC and EuropePMC. Here are reported the interactions of the Supplementary Table 10 of the \"Appendix A. Supplementary material\"."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rogid:DgxWWF7aiKBOUyGXmibtu8Wh+DU10090 rigid:fgfHDv6Re58UdlTN2drWT+GWMmA false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6VNS1 uniprotkb:P16056 intact:EBI-16744951|ensembl:ENSMUSP00000037909|uniprotkb:A4QPD0|uniprotkb:Q9Z2P9|uniprotkb:Q9Z2Q0 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:ntrk3_mouse(display_long)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27118418|imex:IM-29320-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039431(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020446|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|reactome:R-MMU-388844|reactome:R-MMU-9034013|reactome:R-MMU-9034793|reactome:R-MMU-9603381|refseq:NP_032772.3|refseq:NP_877961.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F4|comment:"MET interacts with NTRK3, SYNGAP1 and GRM5 (Fig. 4). HGF-stimulation for 5 minutes resulted in no statistically significant change in NTRK3-MET binding ."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:awHq4B+I8bd3A6XndEgDYNbRS5Y10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:TPMOdeN0O8TSjGKDbiw2hbZFx+U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F6SEU4 uniprotkb:P16056 intact:EBI-5797569|ensembl:ENSMUSP00000141686 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27118445|imex:IM-29320-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F4|comment:HGF-stimulation for 5 minutes resulted in a significant decrease in SYNGAP1-MET binding.|antagonist:HGF-hepatocyte growth factor|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:qtT1jKjnL7zOqrebOoKtBsn56K0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3UVX5 uniprotkb:P16056 intact:EBI-8795045|ensembl:ENSMUSP00000114927 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:grm5_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27118450|imex:IM-29320-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000155358(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|refseq:XP_011239945.1|refseq:NP_001137306.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F4|comment:HGF-stimulation for 5 minutes resulted in a significant increase in GRM5-MET binding.|agonist:HGF -hepatocyte growth factor|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:pA3IUBq9r3mGn7M8R2qnAaYqaT810090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:mg51SvYIDnUWETjK002KMnTyJDw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6VNS1 uniprotkb:P16056 intact:EBI-16744951|ensembl:ENSMUSP00000037909|uniprotkb:A4QPD0|uniprotkb:Q9Z2P9|uniprotkb:Q9Z2Q0 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:ntrk3_mouse(display_long)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27118463|imex:IM-29320-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039431(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020446|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|reactome:R-MMU-388844|reactome:R-MMU-9034013|reactome:R-MMU-9034793|reactome:R-MMU-9603381|refseq:NP_032772.3|refseq:NP_877961.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F3A|comment:"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H) 3H); 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G) and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J)."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:awHq4B+I8bd3A6XndEgDYNbRS5Y10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:TPMOdeN0O8TSjGKDbiw2hbZFx+U false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:F6SEU4 uniprotkb:P16056 intact:EBI-5797569|ensembl:ENSMUSP00000141686 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27118468|imex:IM-29320-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F3B|comment:"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H) 3H) 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G) and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J)."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:qtT1jKjnL7zOqrebOoKtBsn56K0 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q4ACU6 uniprotkb:P16056 intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27118473|imex:IM-29320-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F3C|comment:"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H),3H), 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G), and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J)."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/01 rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:E48Z5qNtq9zbnNKXUUCYA/Z18Hs false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q01097 uniprotkb:P16056 intact:EBI-400125|uniprotkb:Q9DCB2 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:nmde2_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27118478|imex:IM-29320-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032197.3|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-3928662|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|mint:Q01097|dip:DIP-31568N interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F3D|comment:"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H),3H), 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G), and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J)."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:SvjoNuuHCFT+Yj1woYrEvU6n8B010090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:hUeJUTsN++SWJ6Sdy+fzk2Fti4U false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q3UVX5 uniprotkb:P16056 intact:EBI-8795045|ensembl:ENSMUSP00000114927 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:grm5_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27118483|imex:IM-29320-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000155358(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|refseq:XP_011239945.1|refseq:NP_001137306.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:F3E|comment:"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H),3H), 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G), and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J)."|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/10/29 rogid:pA3IUBq9r3mGn7M8R2qnAaYqaT810090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:mg51SvYIDnUWETjK002KMnTyJDw false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q3UVX5 uniprotkb:P16056 intact:EBI-8795045|ensembl:ENSMUSP00000114927 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:grm5_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27120304|imex:IM-29320-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000155358(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|refseq:XP_011239945.1|refseq:NP_001137306.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:SF3|comment:There was modest co-labeling of Met with Ntrk3 and with Grm5 in deep neocortical layers, with far more coexpression in superficial layers.|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:pA3IUBq9r3mGn7M8R2qnAaYqaT810090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:mg51SvYIDnUWETjK002KMnTyJDw false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry) uniprotkb:Q6VNS1 uniprotkb:P16056 intact:EBI-16744951|ensembl:ENSMUSP00000037909|uniprotkb:A4QPD0|uniprotkb:Q9Z2P9|uniprotkb:Q9Z2Q0 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:ntrk3_mouse(display_long)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27120322|imex:IM-29320-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039431(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001764"(neuron migration)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005030"(neurotrophin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020446|interpro:IPR020635|interpro:IPR020777|interpro:IPR031635|interpro:IPR032675|interpro:IPR036179|reactome:R-MMU-388844|reactome:R-MMU-9034013|reactome:R-MMU-9034793|reactome:R-MMU-9603381|refseq:NP_032772.3|refseq:NP_877961.1 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:SF3|comment:There was modest co-labeling of Met with Ntrk3 and with Grm5 in deep neocortical layers, with far more coexpression in superficial layers.|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:awHq4B+I8bd3A6XndEgDYNbRS5Y10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:TPMOdeN0O8TSjGKDbiw2hbZFx+U false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry) uniprotkb:F6SEU4 uniprotkb:P16056 intact:EBI-5797569|ensembl:ENSMUSP00000141686 intact:EBI-1798780|uniprotkb:Q62125 psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym) psi-mi:met_mouse(display_long)|uniprotkb:Met(gene name)|psi-mi:Met(display_short)|uniprotkb:Scatter factor receptor(gene name synonym)|uniprotkb:HGF/SF receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase Met(gene name synonym)|uniprotkb:Proto-oncogene c-Met(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Xie et al. (2016) imex:IM-29320|pubmed:27086544 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27120327|imex:IM-29320-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442 interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR002165(Plexin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016244(Tyrosine-protein kinase, HGF/MSP receptor)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036352|interpro:IPR031148|reactome:R-MMU-1257604|reactome:R-MMU-416550|reactome:R-MMU-5673001|reactome:R-MMU-6806942|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8865999|reactome:R-MMU-8874081|reactome:R-MMU-8875513|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8875791|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005008"(hepatocyte growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014812"(muscle cell migration)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031016"(pancreas development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential) - - - figure legend:SF3|comment:In contrast, there was dense bilaminar colocalization of Met and Syngap1 in deep and superficial layers|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex) - 2021/10/27 2021/11/04 rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090 rogid:3bpWjMJYCVmJ5Wu4i/5Z8p6OOtU10090 rigid:qtT1jKjnL7zOqrebOoKtBsn56K0 false - - - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry)