#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NXL9	uniprotkb:Q16649	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-3951858|uniprotkb:B2R9Y8|uniprotkb:Q14211|uniprotkb:Q6FGQ8|uniprotkb:Q96HS0|ensembl:ENSP00000297689	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:nfil3_human(display_long)|uniprotkb:NFIL3(gene name)|psi-mi:NFIL3(display_short)|uniprotkb:E4BP4(gene name synonym)|uniprotkb:IL3BP1(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Interleukin-3 promoter transcriptional activator(gene name synonym)|uniprotkb:Interleukin-3-binding protein 1(gene name synonym)|uniprotkb:Transcriptional activator NF-IL3A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_005375.2|ensembl:ENSG00000165030(gene)|ensembl:ENST00000297689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:Q16649|reactome:R-HSA-400253|go:"GO:0000785"(chromatin)|refseq:NP_001276928.1|refseq:NP_001276929.1|refseq:XP_016870232.1|refseq:XP_016870233.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:Ra9G92z80ogAKLGyDNnUudk8n8I9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P35250	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P35249	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:O00567	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9BZZ5	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:WYNbM5GNolgFNszccnMEanszDgU9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9Y2X3	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q86X24	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-12165207|ensembl:ENSP00000355167|uniprotkb:A6NMK2|uniprotkb:B3KUK1|uniprotkb:Q4G114|uniprotkb:Q5T5I3|uniprotkb:Q5T5I4|uniprotkb:Q5T5I5|uniprotkb:Q6FIC1|uniprotkb:Q9H0K8	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:horm1_human(display_long)|uniprotkb:HORMAD1(gene name)|psi-mi:HORMAD1(display_short)|uniprotkb:Cancer/testis antigen 46(gene name synonym)|uniprotkb:NOHMA(gene name synonym)|uniprotkb:Newborn ovary HORMA protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000143452(gene)|ensembl:ENST00000361824(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR003511(DNA-binding HORMA)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR036570|refseq:NP_001186758.1|refseq:NP_115508.2|refseq:XP_006711633.1|refseq:XP_006711634.1|refseq:XP_011508355.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:f8V6NzN1+8eIpyrZVRhJ+aiC99Q9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q96S55	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9Y265	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40937	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40938	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1055010|intact:EBI-2512011|uniprotkb:O15252|intact:EBI-1169853|uniprotkb:Q5W0E8|uniprotkb:C9JU95|ensembl:ENSP00000369411	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc3_human(display_long)|uniprotkb:RFC3(gene name)|psi-mi:RFC3(display_short)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002906.1|refseq:NP_853536.2|ensembl:ENSG00000133119(gene)|ensembl:ENST00000380071(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0046683"(response to organophosphorus)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|mint:P40938|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-6804756|dip:DIP-36432N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:XaK3OCno6yS3ubSiJhdBrW52VAw9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P54277	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40692	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P43246	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9UJA3	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27097938|imex:IM-29269-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606	rigid:vpE5FskYlYWppYkL1eGA4/I6KjI	false	ha tag:n-n|flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P35250	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P35249	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P52701	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P42285	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P20585	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1164205|uniprotkb:Q6PJT5|uniprotkb:Q86UQ6|uniprotkb:Q92867|uniprotkb:A6NMM6|uniprotkb:A1L482|uniprotkb:A1L480|ensembl:ENSP00000265081	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh3_human(display_long)|uniprotkb:Divergent upstream protein(gene name synonym)|uniprotkb:Mismatch repair protein 1(gene name synonym)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:DUC1(gene name synonym)|uniprotkb:DUG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002430.3|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P20585|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|go:"GO:0032300"(mismatch repair complex)|ensembl:ENSG00000113318(gene)|ensembl:ENST00000265081(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016020"(membrane)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0032135"(DNA insertion or deletion binding)|dip:DIP-35127N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:6nxGZyJMsk7NfSFhDftKiT/omSE9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:O00487	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q01813	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:O00567	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9Y3B4	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q86X24	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-12165207|ensembl:ENSP00000355167|uniprotkb:A6NMK2|uniprotkb:B3KUK1|uniprotkb:Q4G114|uniprotkb:Q5T5I3|uniprotkb:Q5T5I4|uniprotkb:Q5T5I5|uniprotkb:Q6FIC1|uniprotkb:Q9H0K8	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:horm1_human(display_long)|uniprotkb:HORMAD1(gene name)|psi-mi:HORMAD1(display_short)|uniprotkb:Cancer/testis antigen 46(gene name synonym)|uniprotkb:NOHMA(gene name synonym)|uniprotkb:Newborn ovary HORMA protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000143452(gene)|ensembl:ENST00000361824(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR003511(DNA-binding HORMA)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR036570|refseq:NP_001186758.1|refseq:NP_115508.2|refseq:XP_006711633.1|refseq:XP_006711634.1|refseq:XP_011508355.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:f8V6NzN1+8eIpyrZVRhJ+aiC99Q9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q96S55	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9Y265	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40937	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40938	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1055010|intact:EBI-2512011|uniprotkb:O15252|intact:EBI-1169853|uniprotkb:Q5W0E8|uniprotkb:C9JU95|ensembl:ENSP00000369411	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:rfc3_human(display_long)|uniprotkb:RFC3(gene name)|psi-mi:RFC3(display_short)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002906.1|refseq:NP_853536.2|ensembl:ENSG00000133119(gene)|ensembl:ENST00000380071(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0046683"(response to organophosphorus)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|mint:P40938|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-6804756|dip:DIP-36432N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:XaK3OCno6yS3ubSiJhdBrW52VAw9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P54277	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P40692	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:P43246	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9UJA3	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NXL9	uniprotkb:Q9H0S4	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2515241|ensembl:ENSP00000350698|uniprotkb:Q96NV8|uniprotkb:B3KXP4|uniprotkb:Q96GM0|uniprotkb:G5E955|uniprotkb:Q9UI98	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:ddx47_human(display_long)|uniprotkb:DDX47(gene name)|psi-mi:DDX47(display_short)|uniprotkb:DEAD box protein 47(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098047|imex:IM-29269-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	ensembl:ENSG00000213782(gene)|ensembl:ENST00000358007(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044765|mint:Q9H0S4|rcsb pdb:3BER|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_057439.2|refseq:NP_957518.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1A, 1B, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2022/01/04	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:AhH5kg/8cw6L5385wUw4PR243rY9606	rigid:I3chnKDuMpvny0p28hdDJSMGkGo	false	ha tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UJA3	uniprotkb:Q9NXL9	intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym)	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098094|imex:IM-29269-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rigid:CH4SNBOeqAlBuP2m6UqcVaOR9yw	false	-	ha tag:c-c|flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NXL9	uniprotkb:P20585	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-1164205|uniprotkb:Q6PJT5|uniprotkb:Q86UQ6|uniprotkb:Q92867|uniprotkb:A6NMM6|uniprotkb:A1L482|uniprotkb:A1L480|ensembl:ENSP00000265081	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh3_human(display_long)|uniprotkb:Divergent upstream protein(gene name synonym)|uniprotkb:Mismatch repair protein 1(gene name synonym)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:DUC1(gene name synonym)|uniprotkb:DUG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098115|imex:IM-29269-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_002430.3|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P20585|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|go:"GO:0032300"(mismatch repair complex)|ensembl:ENSG00000113318(gene)|ensembl:ENST00000265081(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016020"(membrane)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0032135"(DNA insertion or deletion binding)|dip:DIP-35127N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:6nxGZyJMsk7NfSFhDftKiT/omSE9606	rigid:D6V1OTyqbZ117CO8FWbpMgYnHfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NXL9	uniprotkb:P54277	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-2893308|ensembl:ENSP00000406490|uniprotkb:D3DPI1|uniprotkb:Q4VAL4|uniprotkb:Q5FBZ8|uniprotkb:Q5FBZ3|uniprotkb:Q5FBZ6	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:pms1_human(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:PMSL1(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098115|imex:IM-29269-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000525.1|ensembl:ENSG00000064933(gene)|ensembl:ENST00000441310(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR036890|interpro:IPR036910|interpro:IPR038973|mint:P54277|rcsb pdb:2CS1|refseq:NP_001276337.1|refseq:XP_016859833.1|refseq:XP_016859837.1|refseq:NP_001121616.1|refseq:NP_001121615.1|refseq:NP_001307974.1|refseq:NP_001307975.1|refseq:NP_001307976.1|refseq:NP_001307977.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:URnCj+2/Inh5Wsc1UFHYh1gowFQ9606	rigid:D6V1OTyqbZ117CO8FWbpMgYnHfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NXL9	uniprotkb:P40692	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098115|imex:IM-29269-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rigid:D6V1OTyqbZ117CO8FWbpMgYnHfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NXL9	uniprotkb:P43246	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098115|imex:IM-29269-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rigid:D6V1OTyqbZ117CO8FWbpMgYnHfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43246	uniprotkb:Q9NXL9	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098141|imex:IM-29269-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1D, 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rigid:12qWaxL/PZdGJmDzAKXBfaFZZSM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43246	uniprotkb:Q9UJA3	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098141|imex:IM-29269-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962	go:"GO:0005634"(nucleus)	-	-	figure legend:Figs. 1D, 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606	rigid:12qWaxL/PZdGJmDzAKXBfaFZZSM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52701	uniprotkb:Q9NXL9	intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098147|imex:IM-29269-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rigid:jQLMWlE+NsWNpBPvy124snoBEOw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40692	uniprotkb:Q9NXL9	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-2804985|uniprotkb:Q8N5S5|uniprotkb:Q2KHJ0|uniprotkb:Q9HCV5|intact:EBI-28972951|uniprotkb:B4DR30|uniprotkb:B9DI77|ensembl:ENSP00000314505|ensembl:ENSP00000480469	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:mcm9_human(display_long)|uniprotkb:C6orf61(gene name synonym)|uniprotkb:MCMDC1(gene name synonym)|uniprotkb:Mini-chromosome maintenance deficient domain-containing protein 1(gene name synonym)|uniprotkb:MCM9(gene name)|psi-mi:MCM9(display_short)|uniprotkb:Minichromosome maintenance 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098152|imex:IM-29269-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	ensembl:ENST00000316068|ensembl:ENSP00000312870|ensembl:ENSP00000314505|ensembl:ENSP00000480469|refseq:NP_060166.2|refseq:NP_694987.1|ensembl:ENSG00000111877(gene)|ensembl:ENST00000316316(transcript)|ensembl:ENST00000619706(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:7DPD|go:"GO:0005524"(ATP binding)	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:CZnc4GbTnlURdHlzMN+0T+VBljQ9606	rigid:pL6/BE18oCFVqSAQp1D9Tb9UNPk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40692	uniprotkb:Q9UJA3	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098157|imex:IM-29269-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2021/09/27	2021/09/30	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606	rigid:Wq/hCTa5AhYHz7Tc764a0KCz+TU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intenz:3.6.4.12	intact:EBI-1203195	intact:EBI-27098640|rhea:"RHEA:13065"	-	psi-mi:mcm8-mcm9_human(display_short)|psi-mi:3.6.4.12(display_long)|intact:MCM8-MCM9 DNA helicase complex(complex recommended name)|intact:"MCM8:MCM9"(complex systematic name)	psi-mi:m13(display_short)|psi-mi:EBI-1203195(display_long)	psi-mi:"MI:0415"(enzymatic study)	Traver et al. (2015)	imex:IM-29269|pubmed:26300262	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10870(bpm13)|taxid:10870(Enterobacteria phage M13)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27098634|imex:IM-29269-17	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:1302"(stable complex)	psi-mi:"MI:0319"(deoxyribonucleic acid)	intact:EBI-27098094(exp-evidence)|complex portal:CPX-7113(complex-primary)|evidence ontology:"ECO:0000353"|go:"GO:0005634"(nucleus)|pubmed:30743181(see-also)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0070716"(mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication)|pubmed:26300262(see-also)	ddbj/embl/genbank:V00604(primary-reference)	go:"O:0003678"	curated-complex:DNA helicase which binds single-stranded DNA and functions in both homologous recombination repair of DNA interstrand crosslinks and DNA mismatch repair.|complex-properties:May be active as a heterohexamer which encircles the DNA strand.	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/09/27	2021/10/06	-	-	-	false	mutation disrupting interaction rate:482-482,358-358	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)